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MTSSAQPIRPSQESQVELVGRRAERRALDGVLSAVSAGRSGVLVLSGVLVLSGEAGIGKTALLDEVAGQI AEGLLVRVAGVESETEFAYAALHQLCIPLFERIEQIPGPQRAALLTAFGQRRSPTPDPFLVGLAVLSLVS EFVHQCPVFLIIDDQQWLDRASSIAIAFVARRLSAEPVGVVFATRTVGEELRGLPELVVGGLTDDDSREL LALNLDGPLDTSVRDRIIVEARGNPLALLEIPRALGRTGLAGGFGAPGVPLTHSLEGAFRHQLHGLPLPT RRLLALAAAEPAGDASTLWRAAEVLGIETNAAVPAVEAGLAEIGSRVRFRHPLIRSTAYRSVALSDRQLI HSALAAVIDRELDPDRRAWHLGHAAIGPDDEVAAELERCATRVRARGGVAAAAAFLERASALTLDPSNRC DRTIAAASAKAQAGALDVAKDLLKVADAAPMTELQRAQADLVRAQLAFISNHGNDAAPLLLGAARRLESI DPTLARETYLDTLSAAIFAGRLAVDGGVLEVSEAASAATRSLNTPGAADLLLDGMTTQHSAGFEKGLPNV REALRIYGPGMTTEQELRWMFLACVAAAHVWDLDRLMSLAVRHVQLSRDTGAVSELPLALSCLITPLLFT GRFGEAARAIDELTAAIDAMGNNLTPYGALSLAAMSGRRDHLQRLGSTAIHNAEHRGEGIGLTVNAWATA LLENGHGRYHAAAEAAVYATSYPGDCTSAGWALIELVEAGSRTGDDAVASAALERLTEMTTPSGTDWGLG VEARSRALTTEGDAAEALYLEAIERLGRAGMGPDQGRAHLLYGEWLRRRRRRVDARAQLRSAHHLFDSIG MDAFAERARVELLATGETAQKRTNSRVAALTAQEAQIARLARDGLSNPEIGARLFISARTVQYHLSKVFA KLGIRSRSQLEHSLPELAT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5449 | - | - | 100% (929) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 0.0 | 48.86% (923) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_1214 | - | 0.0 | 46.24% (930) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1393 | - | 3e-13 | 25.16% (616) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4504 | - | 9e-57 | 29.41% (918) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv1358 | - | 3e-13 | 25.16% (616) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02341 | - | 4e-18 | 29.43% (401) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 46.28% (886) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 0.0 | 43.15% (920) | transcriptional regulatory protein |
| M. avium 104 | MAV_2362 | - | 5e-12 | 23.87% (951) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_3290 | - | 0.0 | 51.55% (906) | regulatory protein |
| M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 44.90% (931) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 9e-26 | 28.52% (568) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1393|M.bovis_AF2122/97 MFLSAPAFRVEPTRSRHSALRWARHRRFADVPRWQMLRSLQIADQIARTG
Rv1358|M.tuberculosis_H37Rv MFLSAPAFRVEPTRSRHSALRWARHRRFADGPRWQMLRSLQIADQIARTG
Mvan_5449|M.vanbaalenii_PYR-1 ------------MTSSAQPIRPSQESQVELVGRRAERRALDGVLSAVSAG
MSMEG_3290|M.smegmatis_MC2_155 -------------MVQVSGVSRDDGPVAGLIGRRDECAVLDQLVDAVAGG
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------MSSRDGDVVLHGRAAEIATLRDVMSTARAG
MMAR_0085|M.marinum_M ------------------------MPTVTLVGRHREQQQLQQLLDAARRG
Mflv_4504|M.gilvum_PYR-GCK --------------MRAALPAAMMNAMSDASPQAADDPQVAGFLCTATSA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 --------------------------------MGREAELRRSLAALSNAE
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 HMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGSTRLSQTR
Rv1358|M.tuberculosis_H37Rv HMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGSTRLSQTR
Mvan_5449|M.vanbaalenii_PYR-1 RSGVLVLSGVLVLSGEAGIGKTALLDEVAGQIAEGLLVRVAG-------V
MSMEG_3290|M.smegmatis_MC2_155 ASRALMIR------GEAGVGKTALLDYAAARAAELQIARIVG-------I
MAB_3361|M.abscessus_ATCC_1997 -----MLR------GQAGVGKTALLRYVLGKASGQLIAQASG-------I
TH_3225|M.thermoresistible__bu SSRVLVLH------GEAGVGKTALLGQLLGDAAGMRCVQVAG-------V
MMAR_0085|M.marinum_M ESGVLVLR------GDAGIGKTTLLTDLVDNAPDLRVLRVRG-------A
Mflv_4504|M.gilvum_PYR-GCK PTGLIIEG-------DAGIGKTTLWLSLLQTARMRGFQVLTAR-----VG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 FHGVALVG-------DAGVGKSTLARMLAKTVESAG--------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 LNELAADYPTLDQNISEAVAAHGGVTRPVDQEVGSGLVVAFLRAGDAIAC
Rv1358|M.tuberculosis_H37Rv LNELAADYPTLDQNISEAVAAHGGVTRPVDQEVGSGLVVAFLRAGDAIAC
Mvan_5449|M.vanbaalenii_PYR-1 ESETEFAYAALHQLCIPLFERIEQIPGPQ----RAALLTAFGQRRSPTPD
MSMEG_3290|M.smegmatis_MC2_155 QSEMELAFAGIHQLCLPLLPRLGHLPVPQ----RDALEVALGMATGSSPD
MAB_3361|M.abscessus_ATCC_1997 QSEMELAFAGLQQFCAPLTKYSGAIPDPQ----REALTIAFGTRSGPPPD
TH_3225|M.thermoresistible__bu ESDMELAYAGLHQLCAPLLDRLDDLPSPQ----RDVLNVAFGRGAGPAPG
MMAR_0085|M.marinum_M EMEMELTYSGVQQLCGPLMSLIGQLPEPQ----LDALEIALGRKRGRAPD
Mflv_4504|M.gilvum_PYR-GCK QAESVMAFAALADLLGAVSDEHFAALPPLQRLALDRVLLRAG-ADGPATD
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 -RTVRFALGTQTGSAVPLG------------------AFSHAVSLMAVNE
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 ALELQLSTLAPMRPRVGVHTGDVRLRGDGTITGSAINESACLRDLAHEGQ
Rv1358|M.tuberculosis_H37Rv ALELQLSTLAPMRPRVGVHTGDVRLRGDGTITGSAINESACLRDLAHEGQ
Mvan_5449|M.vanbaalenii_PYR-1 PFLVGLAVLS----------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 RFLVGLAVLN----------------------------------------
MAB_3361|M.abscessus_ATCC_1997 RFLIGLAVLS----------------------------------------
TH_3225|M.thermoresistible__bu RFLVGLAVLN----------------------------------------
MMAR_0085|M.marinum_M RLLLGLAVLT----------------------------------------
Mflv_4504|M.gilvum_PYR-GCK QRVVAAGFVS----------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 PAVMLAAAHN----------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 TLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRDLRNEF
Rv1358|M.tuberculosis_H37Rv TLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRDLRNEF
Mvan_5449|M.vanbaalenii_PYR-1 LVSEFVHQCPVFLIIDDQQWLDRA--------------------------
MSMEG_3290|M.smegmatis_MC2_155 LLADAAADRPLLCLVDDEQWLDRS--------------------------
MAB_3361|M.abscessus_ATCC_1997 LLAAAAEHQPVLCVIDDAQWLDRV--------------------------
TH_3225|M.thermoresistible__bu LLAAAGADQPLLCVIDDAQWLDRV--------------------------
MMAR_0085|M.marinum_M LVGEASRASPILCVVDDAQWVDSA--------------------------
Mflv_4504|M.gilvum_PYR-GCK LLHILAADAPVLIAIDDVQWLDAS--------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 ---TLSQDKNLVVVVDDAQLLDPL--------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 PPLRMSVGNRSSLPAQFTTFVGRDAQINEVQEVLTNYRLVTLRG------
Rv1358|M.tuberculosis_H37Rv PPLRMSVGNRSSLPAQFTTFVGRDAQINEVQEVLTNYRLVTLRG------
Mvan_5449|M.vanbaalenii_PYR-1 -------------SSIAIAFVARRLSAEPVGVVFATRT-VGEEL------
MSMEG_3290|M.smegmatis_MC2_155 -------------SAQVLAFVARRLGSESVGMIFAARE-PSDAA------
MAB_3361|M.abscessus_ATCC_1997 -------------SLQTLAFVTRRLGSEPVAMLFAVRDGTDSEL------
TH_3225|M.thermoresistible__bu -------------SLQTLGFVARRLMAEPVAMVFALRDDIHEAL------
MMAR_0085|M.marinum_M -------------SVQALAFVARRIHVDPVAMVFATRDRGPDAL------
Mflv_4504|M.gilvum_PYR-GCK -------------SRTAIEFAVRRLKG-AFGVVVTERCVPGDGTTAGWLT
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 -------------SATLVNQLAAWRSARLIVTIRSGEPVLDAVT-----A
MLBr_02341|M.leprae_Br4923 -------------MTTALVCVACGAELRSIAKFCDECGSPVVEAET----
Mb1393|M.bovis_AF2122/97 ----EGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHALG
Rv1358|M.tuberculosis_H37Rv ----EGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHALG
Mvan_5449|M.vanbaalenii_PYR-1 ----RGLPELVVGGLTDDDSRELLALNLDGPLDTSVRDRIIVEARGNPLA
MSMEG_3290|M.smegmatis_MC2_155 ----AGVPALVVRGLRGADARALLDSALSAPLDPRVRDQILAETDGNPLA
MAB_3361|M.abscessus_ATCC_1997 ----AGLPELTVHGLRAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLA
TH_3225|M.thermoresistible__bu ----VGVPALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRGNPLA
MMAR_0085|M.marinum_M ----TGHCELSLQGLEDHDARLVLSTAIPGRLNDSVAETVLAEANGNPLA
Mflv_4504|M.gilvum_PYR-GCK LERPDGLIRVSVPPMDAGRLHALISHRLGRTLTRPVVLRIAEMSGGNPFY
MUL_2555|M.ulcerans_Agy99 --------------------------------MPALSANLVASIDRHPER
MAV_2362|M.avium_104 LLKERLLLTVHVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSGNPLL
MLBr_02341|M.leprae_Br4923 ----PAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIER
:
Mb1393|M.bovis_AF2122/97 LIDRPGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPEL
Rv1358|M.tuberculosis_H37Rv LIDRPGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPEL
Mvan_5449|M.vanbaalenii_PYR-1 LLEIPRALGRTGLAGGFG-------APG-VPLTHSLEGAFRHQLHGLPLP
MSMEG_3290|M.smegmatis_MC2_155 LLELPRTLTRDALAGVFG-------LPGGSGVAADIEHAFGVRIGELPEP
MAB_3361|M.abscessus_ATCC_1997 LLELPRDMTAEELAGGFG-------WPDGGRLAGQIEQTFLRRVQQLPAH
TH_3225|M.thermoresistible__bu LLEVPRTYAVGELAGGFV-------SPGAGSAPSRIEENYVHRIRALPAQ
MMAR_0085|M.marinum_M LLELHNALIRGELAGGYG-------LANATRTETQIERTFVSRLRALPSE
Mflv_4504|M.gilvum_PYR-GCK ALELAHTHVNSGDS----------PPAAEPPLPATLADVVRRRVGLLDDA
MUL_2555|M.ulcerans_Agy99 ITLRCDDLQS---------------------VFAELGAGPGDRVAALPGD
MAV_2362|M.avium_104 LRGFLTAGRDTGALFRTAEG---WQLRGPLRGDRELHDALEYRLQSLSSE
MLBr_02341|M.leprae_Br4923 YGGTVDKFTGDGIMAIFG------------APTALEDHALRACLAALGVQ
:
Mb1393|M.bovis_AF2122/97 SILATSRESIGVTGEVTWVVPSLSPANEAIQLFTERARLVQPNFEIVADN
Rv1358|M.tuberculosis_H37Rv SILATSRESIGVTGEVTWVVPSLSPANEAIQLFTERARLVQPNFEIVADN
Mvan_5449|M.vanbaalenii_PYR-1 -------------TRRLLALAAAEPAGDASTLWRAAEVLGIETNAAVPAV
MSMEG_3290|M.smegmatis_MC2_155 -------------TRDLLLIAAAEPTGDAPLVWRAAARLGIGSDAAAPAV
MAB_3361|M.abscessus_ATCC_1997 -------------TQTLLLAAATDPLGDVTLLARAAQQLGIPMHAIAPAE
TH_3225|M.thermoresistible__bu -------------TRRLLLIAAAEPIGDSALFLRAAALMGIAVDALAPAE
MMAR_0085|M.marinum_M -------------TKTFLLVAAAESTARPEWLWAAAHRLGIGPEAAAPAE
Mflv_4504|M.gilvum_PYR-GCK TR-----------TLLLGVACVADPTVELLARAHGASTDEITAGLERAEA
MUL_2555|M.ulcerans_Agy99 R------------TRRRVCGPACELSG------------GRFRPSARPQS
MAV_2362|M.avium_104 -------------EREVVEILATAGLLNWDILRDICDAEAVAALERRGLI
MLBr_02341|M.leprae_Br4923 -------------EKARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSS
Mb1393|M.bovis_AF2122/97 FAAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGARS
Rv1358|M.tuberculosis_H37Rv FDAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGARS
Mvan_5449|M.vanbaalenii_PYR-1 EAGLAEIGSRVRFRHPLIRSTAYRSVALS---------------------
MSMEG_3290|M.smegmatis_MC2_155 EAELASFDTRVTFQHPLVRSVVYRAAALD---------------------
MAB_3361|M.abscessus_ATCC_1997 AADLVELSTRVRFRHPLVRSAVYISANPL---------------------
TH_3225|M.thermoresistible__bu AARVIQFGPRMRFFHPLMRSAAYRAADPR---------------------
MMAR_0085|M.marinum_M AAGLIAAQGSVRFRHPLIRAAVYHSSSAA---------------------
Mflv_4504|M.gilvum_PYR-GCK AGIVVLEGNRVRFTHPLLAGGVYTDAGPT---------------------
MUL_2555|M.ulcerans_Agy99 CPGLTEAASPGRSRGPLHLARCAAELTIR---------------------
MAV_2362|M.avium_104 RLVTDGSHAVAQLTHPMLGEAATRHAGMVR--------------------
MLBr_02341|M.leprae_Br4923 ALGYTAVGVQVGMAQRMESVAPPGVVMLS---------------------
Mb1393|M.bovis_AF2122/97 TVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAGG
Rv1358|M.tuberculosis_H37Rv TVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAGG
Mvan_5449|M.vanbaalenii_PYR-1 ---DRQLIHSALAAVIDRELDPDRRAWHLGHAAIGPDDEVAAELERCATR
MSMEG_3290|M.smegmatis_MC2_155 ---DRRRAHRALAAATDAEVDPDRRAWHLAHAAAGPDAAAAAELESSAAR
MAB_3361|M.abscessus_ATCC_1997 ---ERRRIHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAWELEQSAGR
TH_3225|M.thermoresistible__bu ---DRRAVHRALAEATDPGADPDRRAWHAANGVTGTDDAVAAELEKSAAR
MMAR_0085|M.marinum_M ---ERRRVHAALAASIAGPDDDDHRVWHRAHAAEAPDAQTADDLERSAER
Mflv_4504|M.gilvum_PYR-GCK ---ARRAMHRAIASVES---HPELRARHLALAASSGDDEIFAALDQAADS
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2362|M.avium_104 -TRQLNGKLARALQKHERTGSRHLRLPHLQSRIRLAEFMLHSDMEPDLDV
MLBr_02341|M.leprae_Br4923 ------------ESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAE
Mb1393|M.bovis_AF2122/97 DDFVERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEKLNES
Rv1358|M.tuberculosis_H37Rv DDFVERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEKLNES
Mvan_5449|M.vanbaalenii_PYR-1 --VRARGGVAAAAAFLERASALTLDPS-------------------NRCD
MSMEG_3290|M.smegmatis_MC2_155 --ARSRGGACAAAAFLERATALTVDPV-------------------LRND
MAB_3361|M.abscessus_ATCC_1997 --AQAKGGVLAAAAFLQRATELTADPA-------------------ARGR
TH_3225|M.thermoresistible__bu --AQQRGGIAATATFLERAVVLTADPG-------------------LRGR
MMAR_0085|M.marinum_M --ARARGGLSAAASFLEHATKLTPDPF-------------------VRAS
Mflv_4504|M.gilvum_PYR-GCK --ARARGAPAAAAELMDLALGLGAHDP----------------------M
MUL_2555|M.ulcerans_Agy99 -----RGDACQAIELLRRAGELSDRPR-------------------RREQ
MAV_2362|M.avium_104 ITEAARDALAMSNVQLGEELARFALDRG------------------GGLP
MLBr_02341|M.leprae_Br4923 ---PRQPTWFSESTLVGREWELATLAA-------------------MLDR
: :
Mb1393|M.bovis_AF2122/97 EEIDGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEIDNLRAAFTWS
Rv1358|M.tuberculosis_H37Rv EEIDGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEIDNLRAAFTWS
Mvan_5449|M.vanbaalenii_PYR-1 RTIAAASAKAQAGALDVAKDLLKVADAAPMTELQRAQADLVRAQLAFISN
MSMEG_3290|M.smegmatis_MC2_155 RALAAAAAKAEAGAFESAQDLLAMVEATSLSDLQQAQVDVLRARLAFVTS
MAB_3361|M.abscessus_ATCC_1997 RALAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAES
TH_3225|M.thermoresistible__bu RALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLRAQLEFARS
MMAR_0085|M.marinum_M RALDAAMTSLEAGMPDSATRLVASAAAAADDELIAARCELIRAKIAFAAS
Mflv_4504|M.gilvum_PYR-GCK RRLKAAENHFLAGDTAKAAAALGEVGSIEPPILRAMATSLLATVRMYDNE
MUL_2555|M.ulcerans_Agy99 LLASAAFVALQAAQLDEAERLLADAGLGGGASASALLISSFISLYRYGDV
MAV_2362|M.avium_104 AALVLAEAVSWQGRGEEAGFVLAHAEPDGDDDWLIARWGCLRAANLFWGC
MLBr_02341|M.leprae_Br4923 SIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVA
.
Mb1393|M.bovis_AF2122/97 RGNGD-----IAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLV
Rv1358|M.tuberculosis_H37Rv RGNGD-----IAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLV
Mvan_5449|M.vanbaalenii_PYR-1 HG--------NDAAPLLLGAARRLESIDPTLARETYLDTLSAAIFAGRLA
MSMEG_3290|M.smegmatis_MC2_155 HG--------SDAPPLLLKAARRLGGIDPDRARAVYLDAMLAAMFAGRLA
MAB_3361|M.abscessus_ATCC_1997 RVGAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLC
TH_3225|M.thermoresistible__bu RAGDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLA
MMAR_0085|M.marinum_M RG--------SDAPPLLLAAAQRMQRLDPSESRKAYLGAVLASILVGRMA
Mflv_4504|M.gilvum_PYR-GCK HR----------QAVDLLRSALDDAADNVPVQVQVLLRLSFALNSIGELD
MUL_2555|M.ulcerans_Agy99 TA----------THRRLVERLQSADDLDGETLTRMVNLLLAVSMFAADPA
MAV_2362|M.avium_104 GD--------AEAARREADTVKKRVSSEAGLHLIDALELSMAFFRGDVET
MLBr_02341|M.leprae_Br4923 FD----------VVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLL
Mb1393|M.bovis_AF2122/97 PAGVWARALAEKVILKAWPATSP-MGAPDIVAQAHHALALARDAGDCAVL
Rv1358|M.tuberculosis_H37Rv PAGVWARALAEKVILKAWPATSP-MGAPDIVAQAHHALALARDAGDCAVL
Mvan_5449|M.vanbaalenii_PYR-1 VDGG--VLEVSEAASAATRSLNT-PGAADLLLDGMTTQHSAGFEKGLPNV
MSMEG_3290|M.smegmatis_MC2_155 TGAN--LVEVAAAARSAPERSGA-AEVSDLLLDWLTAHYGRGYVAARSAL
MAB_3361|M.abscessus_ATCC_1997 PRGG--AVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTL
TH_3225|M.thermoresistible__bu PSGA--LLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPL
MMAR_0085|M.marinum_M TDQHNSSPSVAKAASNAPAAPHP-PRALDVLLDGLVIRLTEGYVAAAPRL
Mflv_4504|M.gilvum_PYR-GCK DARRYARDAVKLAEELGFPGATS-----AALAWAVHVDFQCGRGLDETAL
MUL_2555|M.ulcerans_Agy99 LWQITDGLVDSLADRLG-------------ELSVIYRDAWADAARRGRTV
MAV_2362|M.avium_104 TTELGPGLCESDAVPMATTWAAV--------PTCAALAATGRYSEVGRIA
MLBr_02341|M.leprae_Br4923 LDDLLGIADPAVELPRLDPDARR------RRLTALINVAQLALSRPAVFV
Mb1393|M.bovis_AF2122/97 ARALVACGCGSGCDTEAAQP---YFAEAIELARAINDEWTLSQIDYWQVV
Rv1358|M.tuberculosis_H37Rv ARALVACGCGSGCDTEAAQP---YFAEAIELARAINDEWTLSQIDYWQVV
Mvan_5449|M.vanbaalenii_PYR-1 REALRIYGPGMTTEQELRWM--------FLACVAAAHVWDLDRLMSLAVR
MSMEG_3290|M.smegmatis_MC2_155 GDVLSAFD-GEADDLPLNRM--------LLASTAAHYAWDDVRLDVFTAH
MAB_3361|M.abscessus_ATCC_1997 GEALTLIR-CEAD-RPANTS-WMEQAFPIALESATHEVWDDDMWHHLATR
TH_3225|M.thermoresistible__bu RVALTAMC-ELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEA
MMAR_0085|M.marinum_M RSAIREYLRERDIGVAEP-G------WHDLTARVCLDLFDQDAYNFLAAR
Mflv_4504|M.gilvum_PYR-GCK ARAMKLYDSTFDVPIIFRAP------FVHALAMSWTGRLEQAHQELTAVR
MUL_2555|M.ulcerans_Agy99 TQRLKEQLDRLAELEPWDVMR-------VALAGYYVDLIDDFRSVLVPLA
MAV_2362|M.avium_104 DIGVRAAMSCGMGLHRFNIG--------ISEIIAATDAGDDRAAERIYKR
MLBr_02341|M.leprae_Br4923 VEDVHWIDEVSDSMLADFLA--------VIPQTRSMALVTYRPEYHGALR
:
Mb1393|M.bovis_AF2122/97 GIFISGQPIPLRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANG
Rv1358|M.tuberculosis_H37Rv GIFISGQPIPLRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANG
Mvan_5449|M.vanbaalenii_PYR-1 -----------------HVQLSRDTGAVSELPLALSCLITPLLFTGRFGE
MSMEG_3290|M.smegmatis_MC2_155 -----------------HVERARATGALSEVPIALNSRAIALLFFGDLDG
MAB_3361|M.abscessus_ATCC_1997 -----------------AVHIAREVGALSLLPAALIYRAGMHVHAGELDA
TH_3225|M.thermoresistible__bu -----------------VVRQARDAGALAGLPQALVYRAGVHLLFGEFGL
MMAR_0085|M.marinum_M -----------------QVEDLRAAGALTMLPVALVTFAGVCVSAGNFGQ
Mflv_4504|M.gilvum_PYR-GCK -------------------GVCLERGAESDMMAIAGFLAINHLWRGQITD
MUL_2555|M.ulcerans_Agy99 -------------------DREIEGGAATIALATLALVAAYQLASGQWAE
MAV_2362|M.avium_104 -------------------YAAMAEGLPGAEAMVDAMLGVVRLARGEFPA
MLBr_02341|M.leprae_Br4923 ----------------------HVVGAQIIAVAPLSDVETSTLVAELLGL
* :
Mb1393|M.bovis_AF2122/97 ALALSRDVTAEAEVANDVVTKVLGLYVEAMALSYIGDSAARTIAGAALEA
Rv1358|M.tuberculosis_H37Rv ALALSRDVTAEAEVANDVVTKVLGLYVEAMALSYIGDSAARTIAGAALEA
Mvan_5449|M.vanbaalenii_PYR-1 AARAIDELTAAIDAMGN----NLTPYGALSLAAMSGRRDHLQRLGSTAIH
MSMEG_3290|M.smegmatis_MC2_155 AADAVDEIQAADDATGA----LLAPYAEVGLAAMRGDLARTASLVDATVA
MAB_3361|M.abscessus_ATCC_1997 AAELVQEADAISAATGH----APIRYHSLILAAWRGSEPTAIRLIDEAMR
TH_3225|M.thermoresistible__bu ADTLLTEAESITAATDHR---GPVRYHRLIIAAWRGDAVEAARLIEAAAA
MMAR_0085|M.marinum_M ADALLDESAAIIAATGA----PPRPAIKTYLAAYRGQEQICREGVQQTVD
Mflv_4504|M.gilvum_PYR-GCK AEAEAAEAVERAEQLGGDDVLIIPMTVRGAIAAYAGRVDDARADARWVLA
MUL_2555|M.ulcerans_Agy99 AVDTSQRGVALCSQHHYELFGYQLRGYLGVISACRGDVVRARELAAQVRV
MAV_2362|M.avium_104 ACAAFTRSISLFAKGFPSPWLVVVGAFQAQAEGARGD-STAAAAALWRAD
MLBr_02341|M.leprae_Br4923 DQSVTQIGELITERAAG------NPFFAQEITRELAERGVLTGERGRYAC
.
Mb1393|M.bovis_AF2122/97 ATELGGIYQDLGYGAITRAALAAGDVAAIEASEASWDLRNQHNVVTAHHE
Rv1358|M.tuberculosis_H37Rv ATELGGIYQDLGYGAITRAALAAGDVAAIEASEASWDLRNQHNVVTAHHE
Mvan_5449|M.vanbaalenii_PYR-1 NAEHRGEGIGLTVNAWATALLENGHGRYHAAAEAAVYATSYP--------
MSMEG_3290|M.smegmatis_MC2_155 AVTARGEGNGLTVAWWAEAVLHNGFGSARKALEAASRAAAFP--------
MAB_3361|M.abscessus_ATCC_1997 DGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACEH---------
TH_3225|M.thermoresistible__bu DGEARGEGRLMGLTGYAAALLYNGIGRYREALAAARTTCEY---------
MMAR_0085|M.marinum_M SAASRGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGARY---------
Mflv_4504|M.gilvum_PYR-GCK AVRNRKASHIADWPGMTLCFLEESLGNHREALAALDDSFIAAG-------
MUL_2555|M.ulcerans_Agy99 WAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITAPG--------
MAV_2362|M.avium_104 RAYGPHAAVFLPELELARAWERAAAGDTQAATTHATQAAEIAR-------
MLBr_02341|M.leprae_Br4923 STDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFR---------
Mb1393|M.bovis_AF2122/97 LMAQAALVRGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELGK
Rv1358|M.tuberculosis_H37Rv LMAQAALVRGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELGK
Mvan_5449|M.vanbaalenii_PYR-1 ---------------------GDCTSAGWALIELVEAGSRTGDDAVASAA
MSMEG_3290|M.smegmatis_MC2_155 ---------------------PELASANWALIELVEAATRCGAVETAAEA
MAB_3361|M.abscessus_ATCC_1997 ---------------------EDLGLYSWCLIELIEAAVRCGEHDTAVKA
TH_3225|M.thermoresistible__bu ---------------------EDLGFYSWCLHELVEAAARVGETDTAHRA
MMAR_0085|M.marinum_M ---------------------DDVGMCGYLLGELIEAAVRCKEHNAATEA
Mflv_4504|M.gilvum_PYR-GCK -------------------PPTTELMYAWHLPDAIEAMVGVGRLDDAEIL
MUL_2555|M.ulcerans_Agy99 ------------------EFPPLALHATRTLFDLVEAAVHTDRLNEARRH
MAV_2362|M.avium_104 ---------------------------AAGMHAAEMRTRHAAVRFGDRSQ
MLBr_02341|M.leprae_Br4923 --------------------------FGSDLLASLGIDLSVDELIDANLV
:
Mb1393|M.bovis_AF2122/97 ARDDAHAAVACGVGVQTYLAMPDALELLAGL----AGEAGNHGQAVRLFG
Rv1358|M.tuberculosis_H37Rv ARDDAHAAVACGVGVQTYLAMPDALELLAGL----AGEAGNHGQAVRLFG
Mvan_5449|M.vanbaalenii_PYR-1 LERLTEMTTPSGTDWGLGVEARSRALTTEGD----AAEALYLEAIERLGR
MSMEG_3290|M.smegmatis_MC2_155 AADLAELTTSSGTDWALGLAARARALVSGPA----ESERWYLESIERLEN
MAB_3361|M.abscessus_ATCC_1997 FGQLEERALAAQSDWSQGMVARSRALITVGH----DAEPHYREAIQRLTN
TH_3225|M.thermoresistible__bu LGDIEERAGASGTPWGLGALAGARALLADGD----EADRLFREALDHLSR
MMAR_0085|M.marinum_M LGRLLKRTKASGTPTALGIGASATALVSDGS----IADAAYREAITHLRR
Mflv_4504|M.gilvum_PYR-GCK TAALERNGVEHDRRWMRAVGARCRAMLLAAHGDVAAAEQMAHRAISEHDH
MUL_2555|M.ulcerans_Agy99 VRAAKRLQFADAPPRLAIATGAAEALCASDE----RAPALFEKVLGHPAV
MAV_2362|M.avium_104 TARLERLARILDTPLAEAAADHARGLTQRDG-------DLLDAAAQQFAD
MLBr_02341|M.leprae_Br4923 DQVRFTAPVEYAFRHPLIRTVAYESQLKSDR-------ARLHRRLAAAIE
Mb1393|M.bovis_AF2122/97 AAAAQRQRTGEVRHKIWDAGYEAATAALRDAMGDEDFTAAWAEGAAAPLD
Rv1358|M.tuberculosis_H37Rv AAAAQRQRTGEVRHKIWDAGYEAATAALRDAMGDEDFTAAWAEGAAAPLD
Mvan_5449|M.vanbaalenii_PYR-1 AGMGPDQGRAHLLYGEWLRRRRRRVDARAQLRSAHHLFDSIGMDAFAERA
MSMEG_3290|M.smegmatis_MC2_155 TRARAELARSRLVYGEWLRRERRRTAARSELRTAHEMFSAMGMSAFAARA
MAB_3361|M.abscessus_ATCC_1997 TRISAHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAERA
TH_3225|M.thermoresistible__bu SRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAERS
MMAR_0085|M.marinum_M SPVAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAERA
Mflv_4504|M.gilvum_PYR-GCK LPMPFERARTRLLLGQLQRRLRQKATAAKNLTDALHTFEQLGTPLWAQRA
MUL_2555|M.ulcerans_Agy99 ASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRA
MAV_2362|M.avium_104 LGALACAADAAAQAAGEHARRGDRGKKFESSAWAHALASRYELHTPAVEA
MLBr_02341|M.leprae_Br4923 ARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVR--AARV
:
Mb1393|M.bovis_AF2122/97 EAIAYAQRGRGERKRPSNGWDALTPAEHKIVKLVTEGLVTKDIAARLFVS
Rv1358|M.tuberculosis_H37Rv EAIAYAQRGRGERKRPSNGWDALTPAEHKIVKLVTEGLVTKDIAARLFVS
Mvan_5449|M.vanbaalenii_PYR-1 RVELLATGETAQKRTNSRVAA-LTAQEAQIARLARDGLSNPEIGARLFIS
MSMEG_3290|M.smegmatis_MC2_155 QRELAAAGDRIRETVIAAVDHRLTAQEAHIARLARDGLSNPEIGARLFIS
MAB_3361|M.abscessus_ATCC_1997 ERELRATGAKVRKRSASSEKA-LTAQEAQIARMAGQGLTNQEIAAQLFIS
TH_3225|M.thermoresistible__bu RRELIAVGEKVRRQPLTSGDE-LTAQEAQIAGLAADGLTNQEIGAQLFLS
MMAR_0085|M.marinum_M RRELSATGEAVYVQPTGITVD-LTTQESHIARLARDGYTNAEIAGLLFIS
Mflv_4504|M.gilvum_PYR-GCK RSELAR--------AVVAPAEGLTPSEQKVAEMAAAGATNKDIAAAMFIS
MUL_2555|M.ulcerans_Agy99 RNELRAAGTAVRHSAAVGPAP-LTAQERLVAELAAKGLSNKEIAARLCLS
MAV_2362|M.avium_104 AARPLP----------------FSGRERQIVNLVAAGLSNREIADRLVIS
MLBr_02341|M.leprae_Br4923 SWEHATKIADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQ
. : :. * . . . .
Mb1393|M.bovis_AF2122/97 PRTVQTHLTHIYTKLDVTSRVQLVQEAAQHST------------------
Rv1358|M.tuberculosis_H37Rv PRTVQTHLTHIYTKLDVTSRVQLVQEAAQHST------------------
Mvan_5449|M.vanbaalenii_PYR-1 ARTVQYHLSKVFAKLGIRSRSQLEHSLPELAT------------------
MSMEG_3290|M.smegmatis_MC2_155 ARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR-----------------
MAB_3361|M.abscessus_ATCC_1997 SHTVEWHLRKVFAKRGITSRRQLRSGR-----------------------
TH_3225|M.thermoresistible__bu VHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW-----------------
MMAR_0085|M.marinum_M ARTVEWHLSKIFAKLGVTSRRELRAILMESP-------------------
Mflv_4504|M.gilvum_PYR-GCK SKTVEHNLTRIYRKLGISSRAELGRRMDQPGL------------------
MUL_2555|M.ulcerans_Agy99 PRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI-------------
MAV_2362|M.avium_104 VRTVEGHLYRLFTKLGINSREQLTLLVAREPRGRRELLGHSNPSLGDQDD
MLBr_02341|M.leprae_Br4923 LCNATGDKAPLAVATVGPAIDHVYQDRLH---------------------
.. . : :
Mb1393|M.bovis_AF2122/97 ------
Rv1358|M.tuberculosis_H37Rv ------
Mvan_5449|M.vanbaalenii_PYR-1 ------
MSMEG_3290|M.smegmatis_MC2_155 ------
MAB_3361|M.abscessus_ATCC_1997 ------
TH_3225|M.thermoresistible__bu ------
MMAR_0085|M.marinum_M ------
Mflv_4504|M.gilvum_PYR-GCK ------
MUL_2555|M.ulcerans_Agy99 ------
MAV_2362|M.avium_104 VHPHAG
MLBr_02341|M.leprae_Br4923 ------