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M. marinum M MMAR_0085 (-)

annotation: transcriptional regulatory protein
coordinates: 84893 - 87637
length: 914

MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDAGIGKTTLLTDLVDNAPDLRVLRVRGAEMEMELT
YSGVQQLCGPLMSLIGQLPEPQLDALEIALGRKRGRAPDRLLLGLAVLTLVGEASRASPILCVVDDAQWV
DSASVQALAFVARRIHVDPVAMVFATRDRGPDALTGHCELSLQGLEDHDARLVLSTAIPGRLNDSVAETV
LAEANGNPLALLELHNALIRGELAGGYGLANATRTETQIERTFVSRLRALPSETKTFLLVAAAESTARPE
WLWAAAHRLGIGPEAAAPAEAAGLIAAQGSVRFRHPLIRAAVYHSSSAAERRRVHAALAASIAGPDDDDH
RVWHRAHAAEAPDAQTADDLERSAERARARGGLSAAASFLEHATKLTPDPFVRASRALDAAMTSLEAGMP
DSATRLVASAAAAADDELIAARCELIRAKIAFAASRGSDAPPLLLAAAQRMQRLDPSESRKAYLGAVLAS
ILVGRMATDQHNSSPSVAKAASNAPAAPHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERDIG
VAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAAGALTMLPVALVTFAGVCVSAGNFGQADALLDES
AAIIAATGAPPRPAIKTYLAAYRGQEQICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAF
NAAASGARYDDVGMCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALGIGASATALVSDGSI
ADAAYREAITHLRRSPVAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAERARRELSA
TGEAVYVQPTGITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRELRAIL
MESP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_0085--100% (914)transcriptional regulatory protein
M. marinum MMMAR_1324-4e-7331.04% (915) hypothetical protein MMAR_1324
M. marinum MMMAR_5254-5e-1625.76% (625) membrane-anchored adenylyl cyclase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0914c-1e-1024.72% (623) LuxR family transcriptional regulator
M. gilvum PYR-GCKMflv_1156-3e-5427.38% (935) regulatory protein, LuxR
M. tuberculosis H37RvRv0890c-2e-1024.72% (623) LuxR family transcriptional regulator
M. leprae Br4923MLBr_02341-3e-1727.59% (435) putative regulatory protein
M. abscessus ATCC 19977MAB_3361-0.045.06% (890) LuxR family transcriptional regulator
M. avium 104MAV_2362-2e-1423.44% (964) TPR repeat-containing protein
M. smegmatis MC2 155MSMEG_3290-0.044.99% (918) regulatory protein
M. thermoresistible (build 8)TH_3225-0.045.22% (920) PUTATIVE regulatory protein, LuxR
M. ulcerans Agy99MUL_2555-3e-3028.57% (567) hypothetical protein MUL_2555
M. vanbaalenii PYR-1Mvan_5002-0.046.20% (920) regulatory protein, LuxR

CLUSTAL 2.0.9 multiple sequence alignment


Mb0914c|M.bovis_AF2122/97           ---------------------------------MRALLAQNRLVTLCGTG
Rv0890c|M.tuberculosis_H37Rv        ---------------------------------MRALLAQNRLVTLCGTG
TH_3225|M.thermoresistible__bu      ----MSSRD-----GDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEA
Mvan_5002|M.vanbaalenii_PYR-1       MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRTGASRSLVLRGEA
MAB_3361|M.abscessus_ATCC_1997      --------------------------------------------MLRGQA
MSMEG_3290|M.smegmatis_MC2_155      --MVQVSGVSRDDGPVAGLIGRRDECAVLDQLVDAVAGGASRALMIRGEA
MMAR_0085|M.marinum_M               -------------MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDA
Mflv_1156|M.gilvum_PYR-GCK          -------------------------MKAVDDFLAGLQQLQPAGLLIEGEA
MUL_2555|M.ulcerans_Agy99           --------------------------------------------------
MAV_2362|M.avium_104                ----------------------MGREAELRRSLAALSNAEFHGVALVGDA
MLBr_02341|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0914c|M.bovis_AF2122/97           GVGKTRLAIQIAS--------ASELRDGLCFVDLAPITESGIVA-ATAAR
Rv0890c|M.tuberculosis_H37Rv        GVGKTRLAIQIAS--------ASELRDGLCFVDLAPITESGIVA-ATAAR
TH_3225|M.thermoresistible__bu      GVGKTALLGQLLGDA--AGMRCVQVAGVESDMELAYAGLHQLCA-PLLDR
Mvan_5002|M.vanbaalenii_PYR-1       GIGKTALLDHVVAQA--EGFRTTYVAGVESDMELAFAGLHQLCA-PLLTH
MAB_3361|M.abscessus_ATCC_1997      GVGKTALLRYVLGKA--SGQLIAQASGIQSEMELAFAGLQQFCA-PLTKY
MSMEG_3290|M.smegmatis_MC2_155      GVGKTALLDYAAARA--AELQIARIVGIQSEMELAFAGIHQLCL-PLLPR
MMAR_0085|M.marinum_M               GIGKTTLLTDLVDNA--PDLRVLRVRGAEMEMELTYSGVQQLCG-PLMSL
Mflv_1156|M.gilvum_PYR-GCK          GIGKTTMLAGVVDAARQAGFRVLSAHGDQSGSGLAHAAIADLFAGVQTDI
MUL_2555|M.ulcerans_Agy99           --------------------------------------------------
MAV_2362|M.avium_104                GVGKSTLARMLAKTVESAGRTVRFALGTQTGSAVPLGAFSHAVSLMAVNE
MLBr_02341|M.leprae_Br4923          ----------------------MTTALVCVACGAELRSIAKFCDECGSPV
                                                                                      

Mb0914c|M.bovis_AF2122/97           AVGLPDQPGRSTMDSLRRFIGN--RRMLMVLDNCEHLLDACAALVVELLG
Rv0890c|M.tuberculosis_H37Rv        AVGLPDQPGRSTMDSLRRFIGN--RRMLMVLDNCEHLLDACAALVVELLG
TH_3225|M.thermoresistible__bu      LDDLPSPQRDVLNVAFGRGAGP--APGRFLVGLAVLNLLAAAGADQPLLC
Mvan_5002|M.vanbaalenii_PYR-1       LDELPDPQRDALTVAFGQGAGA--TPDRFLVGLAVLSLMAAASTGGPLLC
MAB_3361|M.abscessus_ATCC_1997      SGAIPDPQREALTIAFGTRSGP--PPDRFLIGLAVLSLLAAAAEHQPVLC
MSMEG_3290|M.smegmatis_MC2_155      LGHLPVPQRDALEVALGMATGS--SPDRFLVGLAVLNLLADAAADRPLLC
MMAR_0085|M.marinum_M               IGQLPEPQLDALEIALGRKRGR--APDRLLLGLAVLTLVGEASRASPILC
Mflv_1156|M.gilvum_PYR-GCK          LDGLPELQRRAADGVLRRGDGTGGPTDERVIAAALLGAVHGSATRTPVLV
MUL_2555|M.ulcerans_Agy99           --------------------------------------------------
MAV_2362|M.avium_104                PAVMLAAAHNTLSQDKNLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVT
MLBr_02341|M.leprae_Br4923          VEAETPAEYKQVTVLFADVVGS---------------------------M
                                                                                      

Mb0914c|M.bovis_AF2122/97           ACPELTILAT-SREPIGMAGEITW---------RVPS---MSITDEAVEL
Rv0890c|M.tuberculosis_H37Rv        ACPELTILAT-SREPIGMAGEITW---------RVPS---MSITDEAVEL
TH_3225|M.thermoresistible__bu      VIDDAQWLDRVSLQTLGFVARRLM---------AEPVAMVFALRDDIHEA
Mvan_5002|M.vanbaalenii_PYR-1       VIDDAQWLDQVSVQTLAFVARRLL---------AEPIAMVFAARDTGAEA
MAB_3361|M.abscessus_ATCC_1997      VIDDAQWLDRVSLQTLAFVTRRLG---------SEPVAMLFAVRDGTDSE
MSMEG_3290|M.smegmatis_MC2_155      LVDDEQWLDRSSAQVLAFVARRLG---------SESVGMIFAARE-PSDA
MMAR_0085|M.marinum_M               VVDDAQWVDSASVQALAFVARRIH---------VDPVAMVFATRDRGPDA
Mflv_1156|M.gilvum_PYR-GCK          AVDDVQWLDPSSVAVLAFVARRVKGRVGFVVAERPGVGPGLPAATWLQVG
MUL_2555|M.ulcerans_Agy99           --------------------------------------------------
MAV_2362|M.avium_104                IRSGEPVLDAVTALLKERLLLTVH--------------------------
MLBr_02341|M.leprae_Br4923          DIAAAVGLERLREIMTELVSRAAG---------------VIERYGGTVDK
                                                                                      

Mb0914c|M.bovis_AF2122/97           FADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLE
Rv0890c|M.tuberculosis_H37Rv        FADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLE
TH_3225|M.thermoresistible__bu      LVGVPALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLE
Mvan_5002|M.vanbaalenii_PYR-1       LSGLPELAVPGLSDGEARDLLDSVVVGRLDDRVRDRIIAETRGNPLALLD
MAB_3361|M.abscessus_ATCC_1997      LAGLPELTVHGLRAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLE
MSMEG_3290|M.smegmatis_MC2_155      AAGVPALVVRGLRGADARALLDSALSAPLDPRVRDQILAETDGNPLALLE
MMAR_0085|M.marinum_M               LTGHCELSLQGLEDHDARLVLSTAIPGRLNDSVAETVLAEANGNPLALLE
Mflv_1156|M.gilvum_PYR-GCK          TGALTRLPVAPMSLGALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALE
MUL_2555|M.ulcerans_Agy99           -----------------MPALSANLVASIDRHPERITLR-----------
MAV_2362|M.avium_104                --------VDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSGNPLLLRG
MLBr_02341|M.leprae_Br4923          FTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQ
                                                            .                         

Mb0914c|M.bovis_AF2122/97           IADGLDDC----FRLLAGGVRG-AVQRQQTLRASIDWSHALLTETEQILF
Rv0890c|M.tuberculosis_H37Rv        IADGLDDC----FRLLAGGVRG-AVQRQQTLRASIDWSHALLTETEQILF
TH_3225|M.thermoresistible__bu      VPRTYAVG----ELAGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLL
Mvan_5002|M.vanbaalenii_PYR-1       LPHNHVGT----ELPGSAATPGSRPLARRLEQSYARRIKALPPQTQLLLL
MAB_3361|M.abscessus_ATCC_1997      LPRDMTAE----ELAGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLL
MSMEG_3290|M.smegmatis_MC2_155      LPRTLTRD----ALAGVFGLPGGSGVAADIEHAFGVRIGELPEPTRDLLL
MMAR_0085|M.marinum_M               LHNALIRG----ELAGGYGLANATRTETQIERTFVSRLRALPSETKTFLL
Mflv_1156|M.gilvum_PYR-GCK          LAR----------VADGAGSRPGQRLPESLSELVRLRVDGLAEDVRDVLL
MUL_2555|M.ulcerans_Agy99           -------------------CDDLQSVFAELGAGPGDRVAALPGDRTRRRV
MAV_2362|M.avium_104                FLTAGRDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLSSEEREVVE
MLBr_02341|M.leprae_Br4923          LRVGLNSGQ---VIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLS
                                                                            :         

Mb0914c|M.bovis_AF2122/97           RRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLT--LLVDKSLVVADDCQ
Rv0890c|M.tuberculosis_H37Rv        RRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLT--LLVDKSLVVADDCQ
TH_3225|M.thermoresistible__bu      IAAAEPIGDSALFLRAAALMGIAVDALAPAEAAR--VIQFGPRMRFFHPL
Mvan_5002|M.vanbaalenii_PYR-1       AAAAEPVGDAAVLIRAAAQLGIAVDMLTPAEAAG--VIELGTRVRFRHPL
MAB_3361|M.abscessus_ATCC_1997      AAATDPLGDVTLLARAAQQLGIPMHAIAPAEAAD--LVELSTRVRFRHPL
MSMEG_3290|M.smegmatis_MC2_155      IAAAEPTGDAPLVWRAAARLGIGSDAAAPAVEAE--LASFDTRVTFQHPL
MMAR_0085|M.marinum_M               VAAAESTARPEWLWAAAHRLGIGPEAAAPAEAAG--LIAAQGSVRFRHPL
Mflv_1156|M.gilvum_PYR-GCK          VAASATSPTVDLLAKAVGVTPAAVTGLVEAAEVEGIVVIDGNRIRFTHPV
MUL_2555|M.ulcerans_Agy99           CGPACELSGGRFRPSARPQSCPGLTEAASPGRSR----------------
MAV_2362|M.avium_104                ILATAGLLNWDILRDICDAEAVAALERRGLIRLVT--DGSHAVAQLTHPM
MLBr_02341|M.leprae_Br4923          ESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLR---------------
                                       :                                              

Mb0914c|M.bovis_AF2122/97           GRTRYRLLET--VRRYALEKLGDSGEADVHARHRDY---YTALAASLNTP
Rv0890c|M.tuberculosis_H37Rv        GRTRYRLLET--VRRYALEKLGDSGEADVHARHRDY---YTALAASLNTP
TH_3225|M.thermoresistible__bu      MRSAAYRAADPRDRRAVHRALAEATDPGADPDRRAW---HAANGVTGTDD
Mvan_5002|M.vanbaalenii_PYR-1       VRSAAYQAADLADRRTVHRALAEATDSATDPDRRAW---HAANAATGPDD
MAB_3361|M.abscessus_ATCC_1997      VRSAVYISANPLERRRIHGVLAGATDPGADPDRRAW---HRAHAAAGTDE
MSMEG_3290|M.smegmatis_MC2_155      VRSVVYRAAALDDRRRAHRALAAATDAEVDPDRRAW---HLAHAAAGPDA
MMAR_0085|M.marinum_M               IRAAVYHSSSAAERRRVHAALAASIAGPDDDDHRVW---HRAHAAEAPDA
Mflv_1156|M.gilvum_PYR-GCK          LANGIYAGADPQRRREVHRRLADLKT---DPELRAR---HLALASTVADE
MUL_2555|M.ulcerans_Agy99           --------------------------------------------------
MAV_2362|M.avium_104                LGEAATRHAGMVRTRQLNGKLARALQKHERTGSRHLRLPHLQSRIRLAEF
MLBr_02341|M.leprae_Br4923          ----------------------------------------------VAEP
                                                                                      

Mb0914c|M.bovis_AF2122/97           ADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLAS---SLQPIWF
Rv0890c|M.tuberculosis_H37Rv        ADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLAS---SLQPIWF
TH_3225|M.thermoresistible__bu      AVAAELEKSAARAQQRGGIAATATFLERAVVLTADPGLRG---RRALAAA
Mvan_5002|M.vanbaalenii_PYR-1       AVAAELEASAARAQARGGVAAAAAFLERAAALTSDPALRG---ARALAAA
MAB_3361|M.abscessus_ATCC_1997      AIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPAARG---RRALAAA
MSMEG_3290|M.smegmatis_MC2_155      AAAAELESSAARARSRGGACAAAAFLERATALTVDPVLRN---DRALAAA
MMAR_0085|M.marinum_M               QTADDLERSAERARARGGLSAAASFLEHATKLTPDPFVRA---SRALDAA
Mflv_1156|M.gilvum_PYR-GCK          TTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVSR------RIRAA
MUL_2555|M.ulcerans_Agy99           GPLHLARCAAELTIRRGDACQAIELLRRAGELSDRPRRRE---QLLASAA
MAV_2362|M.avium_104                MLHSDMEPDLDVITEAARDALAMSNVQLGEELARFALDRGGGLPAALVLA
MLBr_02341|M.leprae_Br4923          RQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLV
                                                         :    .                       

Mb0914c|M.bovis_AF2122/97           GRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSP-
Rv0890c|M.tuberculosis_H37Rv        GRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSP-
TH_3225|M.thermoresistible__bu      QAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLRAQLEFARSRAGDAG
Mvan_5002|M.vanbaalenii_PYR-1       QAKRDAAAPAEAQELLSTAELGRLSELQQAQAARLRAQMEFTRRRGGDTG
MAB_3361|M.abscessus_ATCC_1997      QSKYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAESRVGAFG
MSMEG_3290|M.smegmatis_MC2_155      AAKAEAGAFESAQDLLAMVEATSLSDLQQAQVDVLRARLAFVTSHG----
MMAR_0085|M.marinum_M               MTSLEAGMPDSATRLVASAAAAADDELIAARCELIRAKIAFAASRG----
Mflv_1156|M.gilvum_PYR-GCK          EHHVVAGDMRRAATLLEQALVDLRPGVLCAIALNLLAGVRMV--------
MUL_2555|M.ulcerans_Agy99           FVALQAAQLDEAERLLADAGLGGGASASALLISSFISLYRYG--------
MAV_2362|M.avium_104                EAVSWQGRGEEAGFVLAHAEPDGDDDWLIARWGCLRAANLFWG-------
MLBr_02341|M.leprae_Br4923          AEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISG-------
                                                  .                   .               

Mb0914c|M.bovis_AF2122/97           ----VGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAA--
Rv0890c|M.tuberculosis_H37Rv        ----VGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAA--
TH_3225|M.thermoresistible__bu      GPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAPSGA--
Mvan_5002|M.vanbaalenii_PYR-1       ARPLDETASQLLTAAASFEQLDGYVSREAYLEALAAAMFAGRLGDPGA--
MAB_3361|M.abscessus_ATCC_1997      SVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRGG--
MSMEG_3290|M.smegmatis_MC2_155      ----SDAPPLLLKAARRLGGIDPDRARAVYLDAMLAAMFAGRLATGAN--
MMAR_0085|M.marinum_M               ----SDAPPLLLAAAQRMQRLDPSESRKAYLGAVLASILVGRMATDQHNS
Mflv_1156|M.gilvum_PYR-GCK          -------EDDYIRAVELLERARADADNDAVLVTTLLSLGFCLGMTGSFTA
MUL_2555|M.ulcerans_Agy99           --------DVTATHRRLVERLQSADDLDGETLTRMVNLLLAVSMFAAD--
MAV_2362|M.avium_104                ----CGDAEAARREADTVKKRVSSEAGLHLIDALELSMAFFRGDVETTT-
MLBr_02341|M.leprae_Br4923          -----------LDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELP
                                                                                      

Mb0914c|M.bovis_AF2122/97           APYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDL
Rv0890c|M.tuberculosis_H37Rv        APYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDL
TH_3225|M.thermoresistible__bu      LLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTA
Mvan_5002|M.vanbaalenii_PYR-1       VPRIAAAASAALDRLPESARPVDALLRGIVARITGGVSAGAAPLRLAMDL
MAB_3361|M.abscessus_ATCC_1997      AVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTL
MSMEG_3290|M.smegmatis_MC2_155      LVEVAAAARSAPERSGA-AEVSDLLLDWLTAHYGRGYVAARSALGDVLSA
MMAR_0085|M.marinum_M               SPSVAKAASNAPAAPHP-PRALDVLLDGLVIRLTEGYVAAAPRLRSAIRE
Mflv_1156|M.gilvum_PYR-GCK          QLATVREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLRAVDL
MUL_2555|M.ulcerans_Agy99           -PALWQITDGLVDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDR
MAV_2362|M.avium_104                ELGPGLCESDAVPMATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSC
MLBr_02341|M.leprae_Br4923          RLDPDARRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAV
                                                                                      

Mb0914c|M.bovis_AF2122/97           ADTIGDRFVSR-------HCSLWLSLAQMWAGNLTEALELSREITAEAEA
Rv0890c|M.tuberculosis_H37Rv        ADTIGDRFVSR-------HCSLWLSLAQMWAGNLTEALELSREITAEAEA
TH_3225|M.thermoresistible__bu      MCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARD
Mvan_5002|M.vanbaalenii_PYR-1       MQEQARNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRARD
MAB_3361|M.abscessus_ATCC_1997      IRCEADRPAN--TSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIARE
MSMEG_3290|M.smegmatis_MC2_155      FDGEADDLPLN--------RMLLASTAAHYAWDDVRLDVFTAHHVERARA
MMAR_0085|M.marinum_M               YLRERDIGVAE------PGWHDLTARVCLDLFDQDAYNFLAARQVEDLRA
Mflv_1156|M.gilvum_PYR-GCK          EDPEDNTPIPFR-------ASAARGLSLALTGRLAEADGQLAAVAQRSAQ
MUL_2555|M.ulcerans_Agy99           LAELEPWDVMR------------VALAGYYVDLIDDFRSVLVPLADREIE
MAV_2362|M.avium_104                GMGLHRFNIGIS-----------EIIAATDAGDDRAAERIYKRYAAMAEG
MLBr_02341|M.leprae_Br4923          IPQTRSMALVT-----------YRPEYHGALRHVVGAQIIAVAPLSDVET
                                                                                      

Mb0914c|M.bovis_AF2122/97           SNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYA
Rv0890c|M.tuberculosis_H37Rv        SNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYA
TH_3225|M.thermoresistible__bu      AGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYH
Mvan_5002|M.vanbaalenii_PYR-1       AGALEALPQVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYTPVRYQ
MAB_3361|M.abscessus_ATCC_1997      VGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATG-HAPIRYH
MSMEG_3290|M.smegmatis_MC2_155      TGALSEVPIALNSRAIALLFFGDLDGAADAVDEIQAADDATG-ALLAPYA
MMAR_0085|M.marinum_M               AGALTMLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATG-APPRPAI
Mflv_1156|M.gilvum_PYR-GCK          RGAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMVIAFS
MUL_2555|M.ulcerans_Agy99           GGAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQL
MAV_2362|M.avium_104                LPGAEAMVDAMLG--VVRLARGEFPAACAAFTRSISLFAKGFPSPWLVVV
MLBr_02341|M.leprae_Br4923          STLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERG
                                                                                      

Mb0914c|M.bovis_AF2122/97           AMTYAALAAG--DVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGG
Rv0890c|M.tuberculosis_H37Rv        AMTYAALAAG--DVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGG
TH_3225|M.thermoresistible__bu      RLIIAAWRG---DAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNG
Mvan_5002|M.vanbaalenii_PYR-1       TLTLAAWRG---EPADAEAVIEAAIADANARGEGRVLGAADYAFAVLYNG
MAB_3361|M.abscessus_ATCC_1997      SLILAAWRG---SEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNS
MSMEG_3290|M.smegmatis_MC2_155      EVGLAAMRG---DLARTASLVDATVAAVTARGEGNGLTVAWWAEAVLHNG
MMAR_0085|M.marinum_M               KTYLAAYRG---QEQICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNG
Mflv_1156|M.gilvum_PYR-GCK          ICAAVAAYRG--REDQARDQAAGALAQGGDYVALTVWASATLAFLEVSR-
MUL_2555|M.ulcerans_Agy99           RGYLGVISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFA
MAV_2362|M.avium_104                GAFQAQAEGAR-GDSTAAAAALWRADRAYGPHAAVFLPELELARAWERAA
MLBr_02341|M.leprae_Br4923          RYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDL
                                                                                      

Mb0914c|M.bovis_AF2122/97           DAIAARQFANDAVDATN-----------GWHRMVALTIRARVATARGEPE
Rv0890c|M.tuberculosis_H37Rv        DAIAARQFANDAVDATN-----------GWHRMVALTIRARVATARGEPE
TH_3225|M.thermoresistible__bu      IGRYREALAAARTTCEY-EDLG----FYSWCLHELVEAAARVGETDTAHR
Mvan_5002|M.vanbaalenii_PYR-1       LGRYQEACSAARRACEY-EDLG----VHSWVLAELVEAADHCGDTALAVS
MAB_3361|M.abscessus_ATCC_1997      LGRYELAFMAARRACEH-EDLG----LYSWCLIELIEAAVRCGEHDTAVK
MSMEG_3290|M.smegmatis_MC2_155      FGSARKALEAASRAAAFPPELA----SANWALIELVEAATRCGAVETAAE
MMAR_0085|M.marinum_M               LGQYQEAFNAAASGARY-DDVG----MCGYLLGELIEAAVRCKEHNAATE
Mflv_1156|M.gilvum_PYR-GCK          -GNYEQALEAAEPLVDLYRDFPGTELMSACFMPDAIESLIAVGRLDEAEP
MUL_2555|M.ulcerans_Agy99           EGDYESAYLQATAITAP-GEFPPLALHATRTLFDLVEAAVHTDRLNEARR
MAV_2362|M.avium_104                AGDTQAATTHATQAAEIARAAG---------MHAAEMRTRHAAVRFGDRS
MLBr_02341|M.leprae_Br4923          LASLGIDLSVDELIDAN--------------LVDQVRFTAPVEYAFRHPL
                                     .                                                

Mb0914c|M.bovis_AF2122/97           LARDDAHAALACGAELHIYQGMPDAMELLAGL----AGEVGSHSEGVRLL
Rv0890c|M.tuberculosis_H37Rv        LARDDAHAALACGAELHIYQGMPDAMELLAGL----AGEVGSHSEGVRLL
TH_3225|M.thermoresistible__bu      ALGDIEERAGASGTPWGLGALAGARALLADGD----EADRLFREALDHLS
Mvan_5002|M.vanbaalenii_PYR-1       ALERLQERTADTGTDWGLGTLAGAQALVADDD----HAEALFEESIDRLA
MAB_3361|M.abscessus_ATCC_1997      AFGQLEERALAAQSDWSQGMVARSRALITVGH----DAEPHYREAIQRLT
MSMEG_3290|M.smegmatis_MC2_155      AAADLAELTTSSGTDWALGLAARARALVSGPA----ESERWYLESIERLE
MMAR_0085|M.marinum_M               ALGRLLKRTKASGTPTALGIGASATALVSDGS----IADAAYREAITHLR
Mflv_1156|M.gilvum_PYR-GCK          LIAAFERNGAELDRPWQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHA
MUL_2555|M.ulcerans_Agy99           HVRAAKRLQFADAPPRLAIATGAAEALCASDE----RAPALFEKVLGHPA
MAV_2362|M.avium_104                QTARLERLARILDTPLAEAAADHARGLTQRDG-------DLLDAAAQQFA
MLBr_02341|M.leprae_Br4923          IRTVAYESQLKSDRARLHRRLAAAIEARAPHS-----VDQHAVLIAEHLE
                                          .                                        .  

Mb0914c|M.bovis_AF2122/97           GAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALST
Rv0890c|M.tuberculosis_H37Rv        GAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALST
TH_3225|M.thermoresistible__bu      RSRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAER
Mvan_5002|M.vanbaalenii_PYR-1       RTRVAVHLARAHLRYGEWLRRALRRNDAREQLTLASGMFTRFGAAAFAER
MAB_3361|M.abscessus_ATCC_1997      NTRISAHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAER
MSMEG_3290|M.smegmatis_MC2_155      NTRARAELARSRLVYGEWLRRERRRTAARSELRTAHEMFSAMGMSAFAAR
MMAR_0085|M.marinum_M               RSPVAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAER
Mflv_1156|M.gilvum_PYR-GCK          RLPMPFERARSALTLGEVLRRLRRR-DAAAAVRDALAQFEELGVPLWVAR
MUL_2555|M.ulcerans_Agy99           VASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQR
MAV_2362|M.avium_104                DLGALACAADAAAQAAGEHARRGDRGKKFESSAWAHALASRYELHTPAVE
MLBr_02341|M.leprae_Br4923          AAGDLHAAYGWHMRAAAWATN-----QDVRAARVSWEHATKIADALTAED
                                                                                      

Mb0914c|M.bovis_AF2122/97           DEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFV
Rv0890c|M.tuberculosis_H37Rv        DEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFV
TH_3225|M.thermoresistible__bu      SRRELIAVGEKVRRQPLTSGDE-LTAQEAQIAGLAADGLTNQEIGAQLFL
Mvan_5002|M.vanbaalenii_PYR-1       TRRELIATGEKARRQPVTSGAQ-LTAQESQIARLAGDGLTNQEIGAQLFI
MAB_3361|M.abscessus_ATCC_1997      AERELRATGAKVRKRSASSEKA-LTAQEAQIARMAGQGLTNQEIAAQLFI
MSMEG_3290|M.smegmatis_MC2_155      AQRELAAAGDRIRETVIAAVDHRLTAQEAHIARLARDGLSNPEIGARLFI
MMAR_0085|M.marinum_M               ARRELSATGEAVYVQPTGITVD-LTTQESHIARLARDGYTNAEIAGLLFI
Mflv_1156|M.gilvum_PYR-GCK          ARIALSGLAVSG-----SAVGSELTDSERRIAELAASGMSNRDVAETLFV
MUL_2555|M.ulcerans_Agy99           ARNELRAAGTAVRHSAAVGPAP-LTAQERLVAELAAKGLSNKEIAARLCL
MAV_2362|M.avium_104                AAARPLP----------------FSGRERQIVNLVAAGLSNREIADRLVI
MLBr_02341|M.leprae_Br4923          PHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATV
                                                            :      .     .  :        :

Mb0914c|M.bovis_AF2122/97           SPRTVQTHLTHVYAKLGLASRVQLVDEAARRGSPS---------------
Rv0890c|M.tuberculosis_H37Rv        SPRTVQTHLTHVYAKLGLPSRVQLVDEAARRGSPS---------------
TH_3225|M.thermoresistible__bu      SVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW----------------
Mvan_5002|M.vanbaalenii_PYR-1       STHTVDWHLRKVFVKLGITSRRQLRSASWAS-------------------
MAB_3361|M.abscessus_ATCC_1997      SSHTVEWHLRKVFAKRGITSRRQLRSGR----------------------
MSMEG_3290|M.smegmatis_MC2_155      SARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR----------------
MMAR_0085|M.marinum_M               SARTVEWHLSKIFAKLGVTSRRELRAILMESP------------------
Mflv_1156|M.gilvum_PYR-GCK          SVKTIETNLSRVYRKLGIRSRAQLGRMLR---------------------
MUL_2555|M.ulcerans_Agy99           SPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI------------
MAV_2362|M.avium_104                SVRTVEGHLYRLFTKLGINSREQLTLLVAREPRGRRELLGHSNPSLGDQD
MLBr_02341|M.leprae_Br4923          GPAIDHVYQDRLH-------------------------------------
                                    .         ::.                                     

Mb0914c|M.bovis_AF2122/97           -------
Rv0890c|M.tuberculosis_H37Rv        -------
TH_3225|M.thermoresistible__bu      -------
Mvan_5002|M.vanbaalenii_PYR-1       -------
MAB_3361|M.abscessus_ATCC_1997      -------
MSMEG_3290|M.smegmatis_MC2_155      -------
MMAR_0085|M.marinum_M               -------
Mflv_1156|M.gilvum_PYR-GCK          -------
MUL_2555|M.ulcerans_Agy99           -------
MAV_2362|M.avium_104                DVHPHAG
MLBr_02341|M.leprae_Br4923          -------