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MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDAGIGKTTLLTDLVDNAPDLRVLRVRGAEMEMELT YSGVQQLCGPLMSLIGQLPEPQLDALEIALGRKRGRAPDRLLLGLAVLTLVGEASRASPILCVVDDAQWV DSASVQALAFVARRIHVDPVAMVFATRDRGPDALTGHCELSLQGLEDHDARLVLSTAIPGRLNDSVAETV LAEANGNPLALLELHNALIRGELAGGYGLANATRTETQIERTFVSRLRALPSETKTFLLVAAAESTARPE WLWAAAHRLGIGPEAAAPAEAAGLIAAQGSVRFRHPLIRAAVYHSSSAAERRRVHAALAASIAGPDDDDH RVWHRAHAAEAPDAQTADDLERSAERARARGGLSAAASFLEHATKLTPDPFVRASRALDAAMTSLEAGMP DSATRLVASAAAAADDELIAARCELIRAKIAFAASRGSDAPPLLLAAAQRMQRLDPSESRKAYLGAVLAS ILVGRMATDQHNSSPSVAKAASNAPAAPHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERDIG VAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAAGALTMLPVALVTFAGVCVSAGNFGQADALLDES AAIIAATGAPPRPAIKTYLAAYRGQEQICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAF NAAASGARYDDVGMCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALGIGASATALVSDGSI ADAAYREAITHLRRSPVAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAERARRELSA TGEAVYVQPTGITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRELRAIL MESP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0085 | - | - | 100% (914) | transcriptional regulatory protein |
M. marinum M | MMAR_1324 | - | 4e-73 | 31.04% (915) | hypothetical protein MMAR_1324 |
M. marinum M | MMAR_5254 | - | 5e-16 | 25.76% (625) | membrane-anchored adenylyl cyclase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0914c | - | 1e-10 | 24.72% (623) | LuxR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_1156 | - | 3e-54 | 27.38% (935) | regulatory protein, LuxR |
M. tuberculosis H37Rv | Rv0890c | - | 2e-10 | 24.72% (623) | LuxR family transcriptional regulator |
M. leprae Br4923 | MLBr_02341 | - | 3e-17 | 27.59% (435) | putative regulatory protein |
M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 45.06% (890) | LuxR family transcriptional regulator |
M. avium 104 | MAV_2362 | - | 2e-14 | 23.44% (964) | TPR repeat-containing protein |
M. smegmatis MC2 155 | MSMEG_3290 | - | 0.0 | 44.99% (918) | regulatory protein |
M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 45.22% (920) | PUTATIVE regulatory protein, LuxR |
M. ulcerans Agy99 | MUL_2555 | - | 3e-30 | 28.57% (567) | hypothetical protein MUL_2555 |
M. vanbaalenii PYR-1 | Mvan_5002 | - | 0.0 | 46.20% (920) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment Mb0914c|M.bovis_AF2122/97 ---------------------------------MRALLAQNRLVTLCGTG Rv0890c|M.tuberculosis_H37Rv ---------------------------------MRALLAQNRLVTLCGTG TH_3225|M.thermoresistible__bu ----MSSRD-----GDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEA Mvan_5002|M.vanbaalenii_PYR-1 MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRTGASRSLVLRGEA MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------MLRGQA MSMEG_3290|M.smegmatis_MC2_155 --MVQVSGVSRDDGPVAGLIGRRDECAVLDQLVDAVAGGASRALMIRGEA MMAR_0085|M.marinum_M -------------MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDA Mflv_1156|M.gilvum_PYR-GCK -------------------------MKAVDDFLAGLQQLQPAGLLIEGEA MUL_2555|M.ulcerans_Agy99 -------------------------------------------------- MAV_2362|M.avium_104 ----------------------MGREAELRRSLAALSNAEFHGVALVGDA MLBr_02341|M.leprae_Br4923 -------------------------------------------------- Mb0914c|M.bovis_AF2122/97 GVGKTRLAIQIAS--------ASELRDGLCFVDLAPITESGIVA-ATAAR Rv0890c|M.tuberculosis_H37Rv GVGKTRLAIQIAS--------ASELRDGLCFVDLAPITESGIVA-ATAAR TH_3225|M.thermoresistible__bu GVGKTALLGQLLGDA--AGMRCVQVAGVESDMELAYAGLHQLCA-PLLDR Mvan_5002|M.vanbaalenii_PYR-1 GIGKTALLDHVVAQA--EGFRTTYVAGVESDMELAFAGLHQLCA-PLLTH MAB_3361|M.abscessus_ATCC_1997 GVGKTALLRYVLGKA--SGQLIAQASGIQSEMELAFAGLQQFCA-PLTKY MSMEG_3290|M.smegmatis_MC2_155 GVGKTALLDYAAARA--AELQIARIVGIQSEMELAFAGIHQLCL-PLLPR MMAR_0085|M.marinum_M GIGKTTLLTDLVDNA--PDLRVLRVRGAEMEMELTYSGVQQLCG-PLMSL Mflv_1156|M.gilvum_PYR-GCK GIGKTTMLAGVVDAARQAGFRVLSAHGDQSGSGLAHAAIADLFAGVQTDI MUL_2555|M.ulcerans_Agy99 -------------------------------------------------- MAV_2362|M.avium_104 GVGKSTLARMLAKTVESAGRTVRFALGTQTGSAVPLGAFSHAVSLMAVNE MLBr_02341|M.leprae_Br4923 ----------------------MTTALVCVACGAELRSIAKFCDECGSPV Mb0914c|M.bovis_AF2122/97 AVGLPDQPGRSTMDSLRRFIGN--RRMLMVLDNCEHLLDACAALVVELLG Rv0890c|M.tuberculosis_H37Rv AVGLPDQPGRSTMDSLRRFIGN--RRMLMVLDNCEHLLDACAALVVELLG TH_3225|M.thermoresistible__bu LDDLPSPQRDVLNVAFGRGAGP--APGRFLVGLAVLNLLAAAGADQPLLC Mvan_5002|M.vanbaalenii_PYR-1 LDELPDPQRDALTVAFGQGAGA--TPDRFLVGLAVLSLMAAASTGGPLLC MAB_3361|M.abscessus_ATCC_1997 SGAIPDPQREALTIAFGTRSGP--PPDRFLIGLAVLSLLAAAAEHQPVLC MSMEG_3290|M.smegmatis_MC2_155 LGHLPVPQRDALEVALGMATGS--SPDRFLVGLAVLNLLADAAADRPLLC MMAR_0085|M.marinum_M IGQLPEPQLDALEIALGRKRGR--APDRLLLGLAVLTLVGEASRASPILC Mflv_1156|M.gilvum_PYR-GCK LDGLPELQRRAADGVLRRGDGTGGPTDERVIAAALLGAVHGSATRTPVLV MUL_2555|M.ulcerans_Agy99 -------------------------------------------------- MAV_2362|M.avium_104 PAVMLAAAHNTLSQDKNLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVT MLBr_02341|M.leprae_Br4923 VEAETPAEYKQVTVLFADVVGS---------------------------M Mb0914c|M.bovis_AF2122/97 ACPELTILAT-SREPIGMAGEITW---------RVPS---MSITDEAVEL Rv0890c|M.tuberculosis_H37Rv ACPELTILAT-SREPIGMAGEITW---------RVPS---MSITDEAVEL TH_3225|M.thermoresistible__bu VIDDAQWLDRVSLQTLGFVARRLM---------AEPVAMVFALRDDIHEA Mvan_5002|M.vanbaalenii_PYR-1 VIDDAQWLDQVSVQTLAFVARRLL---------AEPIAMVFAARDTGAEA MAB_3361|M.abscessus_ATCC_1997 VIDDAQWLDRVSLQTLAFVTRRLG---------SEPVAMLFAVRDGTDSE MSMEG_3290|M.smegmatis_MC2_155 LVDDEQWLDRSSAQVLAFVARRLG---------SESVGMIFAARE-PSDA MMAR_0085|M.marinum_M VVDDAQWVDSASVQALAFVARRIH---------VDPVAMVFATRDRGPDA Mflv_1156|M.gilvum_PYR-GCK AVDDVQWLDPSSVAVLAFVARRVKGRVGFVVAERPGVGPGLPAATWLQVG MUL_2555|M.ulcerans_Agy99 -------------------------------------------------- MAV_2362|M.avium_104 IRSGEPVLDAVTALLKERLLLTVH-------------------------- MLBr_02341|M.leprae_Br4923 DIAAAVGLERLREIMTELVSRAAG---------------VIERYGGTVDK Mb0914c|M.bovis_AF2122/97 FADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLE Rv0890c|M.tuberculosis_H37Rv FADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLE TH_3225|M.thermoresistible__bu LVGVPALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLE Mvan_5002|M.vanbaalenii_PYR-1 LSGLPELAVPGLSDGEARDLLDSVVVGRLDDRVRDRIIAETRGNPLALLD MAB_3361|M.abscessus_ATCC_1997 LAGLPELTVHGLRAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLE MSMEG_3290|M.smegmatis_MC2_155 AAGVPALVVRGLRGADARALLDSALSAPLDPRVRDQILAETDGNPLALLE MMAR_0085|M.marinum_M LTGHCELSLQGLEDHDARLVLSTAIPGRLNDSVAETVLAEANGNPLALLE Mflv_1156|M.gilvum_PYR-GCK TGALTRLPVAPMSLGALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALE MUL_2555|M.ulcerans_Agy99 -----------------MPALSANLVASIDRHPERITLR----------- MAV_2362|M.avium_104 --------VDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSGNPLLLRG MLBr_02341|M.leprae_Br4923 FTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQ . Mb0914c|M.bovis_AF2122/97 IADGLDDC----FRLLAGGVRG-AVQRQQTLRASIDWSHALLTETEQILF Rv0890c|M.tuberculosis_H37Rv IADGLDDC----FRLLAGGVRG-AVQRQQTLRASIDWSHALLTETEQILF TH_3225|M.thermoresistible__bu VPRTYAVG----ELAGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLL Mvan_5002|M.vanbaalenii_PYR-1 LPHNHVGT----ELPGSAATPGSRPLARRLEQSYARRIKALPPQTQLLLL MAB_3361|M.abscessus_ATCC_1997 LPRDMTAE----ELAGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLL MSMEG_3290|M.smegmatis_MC2_155 LPRTLTRD----ALAGVFGLPGGSGVAADIEHAFGVRIGELPEPTRDLLL MMAR_0085|M.marinum_M LHNALIRG----ELAGGYGLANATRTETQIERTFVSRLRALPSETKTFLL Mflv_1156|M.gilvum_PYR-GCK LAR----------VADGAGSRPGQRLPESLSELVRLRVDGLAEDVRDVLL MUL_2555|M.ulcerans_Agy99 -------------------CDDLQSVFAELGAGPGDRVAALPGDRTRRRV MAV_2362|M.avium_104 FLTAGRDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLSSEEREVVE MLBr_02341|M.leprae_Br4923 LRVGLNSGQ---VIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLS : Mb0914c|M.bovis_AF2122/97 RRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLT--LLVDKSLVVADDCQ Rv0890c|M.tuberculosis_H37Rv RRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLT--LLVDKSLVVADDCQ TH_3225|M.thermoresistible__bu IAAAEPIGDSALFLRAAALMGIAVDALAPAEAAR--VIQFGPRMRFFHPL Mvan_5002|M.vanbaalenii_PYR-1 AAAAEPVGDAAVLIRAAAQLGIAVDMLTPAEAAG--VIELGTRVRFRHPL MAB_3361|M.abscessus_ATCC_1997 AAATDPLGDVTLLARAAQQLGIPMHAIAPAEAAD--LVELSTRVRFRHPL MSMEG_3290|M.smegmatis_MC2_155 IAAAEPTGDAPLVWRAAARLGIGSDAAAPAVEAE--LASFDTRVTFQHPL MMAR_0085|M.marinum_M VAAAESTARPEWLWAAAHRLGIGPEAAAPAEAAG--LIAAQGSVRFRHPL Mflv_1156|M.gilvum_PYR-GCK VAASATSPTVDLLAKAVGVTPAAVTGLVEAAEVEGIVVIDGNRIRFTHPV MUL_2555|M.ulcerans_Agy99 CGPACELSGGRFRPSARPQSCPGLTEAASPGRSR---------------- MAV_2362|M.avium_104 ILATAGLLNWDILRDICDAEAVAALERRGLIRLVT--DGSHAVAQLTHPM MLBr_02341|M.leprae_Br4923 ESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLR--------------- : Mb0914c|M.bovis_AF2122/97 GRTRYRLLET--VRRYALEKLGDSGEADVHARHRDY---YTALAASLNTP Rv0890c|M.tuberculosis_H37Rv GRTRYRLLET--VRRYALEKLGDSGEADVHARHRDY---YTALAASLNTP TH_3225|M.thermoresistible__bu MRSAAYRAADPRDRRAVHRALAEATDPGADPDRRAW---HAANGVTGTDD Mvan_5002|M.vanbaalenii_PYR-1 VRSAAYQAADLADRRTVHRALAEATDSATDPDRRAW---HAANAATGPDD MAB_3361|M.abscessus_ATCC_1997 VRSAVYISANPLERRRIHGVLAGATDPGADPDRRAW---HRAHAAAGTDE MSMEG_3290|M.smegmatis_MC2_155 VRSVVYRAAALDDRRRAHRALAAATDAEVDPDRRAW---HLAHAAAGPDA MMAR_0085|M.marinum_M IRAAVYHSSSAAERRRVHAALAASIAGPDDDDHRVW---HRAHAAEAPDA Mflv_1156|M.gilvum_PYR-GCK LANGIYAGADPQRRREVHRRLADLKT---DPELRAR---HLALASTVADE MUL_2555|M.ulcerans_Agy99 -------------------------------------------------- MAV_2362|M.avium_104 LGEAATRHAGMVRTRQLNGKLARALQKHERTGSRHLRLPHLQSRIRLAEF MLBr_02341|M.leprae_Br4923 ----------------------------------------------VAEP Mb0914c|M.bovis_AF2122/97 ADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLAS---SLQPIWF Rv0890c|M.tuberculosis_H37Rv ADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLAS---SLQPIWF TH_3225|M.thermoresistible__bu AVAAELEKSAARAQQRGGIAATATFLERAVVLTADPGLRG---RRALAAA Mvan_5002|M.vanbaalenii_PYR-1 AVAAELEASAARAQARGGVAAAAAFLERAAALTSDPALRG---ARALAAA MAB_3361|M.abscessus_ATCC_1997 AIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPAARG---RRALAAA MSMEG_3290|M.smegmatis_MC2_155 AAAAELESSAARARSRGGACAAAAFLERATALTVDPVLRN---DRALAAA MMAR_0085|M.marinum_M QTADDLERSAERARARGGLSAAASFLEHATKLTPDPFVRA---SRALDAA Mflv_1156|M.gilvum_PYR-GCK TTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVSR------RIRAA MUL_2555|M.ulcerans_Agy99 GPLHLARCAAELTIRRGDACQAIELLRRAGELSDRPRRRE---QLLASAA MAV_2362|M.avium_104 MLHSDMEPDLDVITEAARDALAMSNVQLGEELARFALDRGGGLPAALVLA MLBr_02341|M.leprae_Br4923 RQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLV : . Mb0914c|M.bovis_AF2122/97 GRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSP- Rv0890c|M.tuberculosis_H37Rv GRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSP- TH_3225|M.thermoresistible__bu QAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLRAQLEFARSRAGDAG Mvan_5002|M.vanbaalenii_PYR-1 QAKRDAAAPAEAQELLSTAELGRLSELQQAQAARLRAQMEFTRRRGGDTG MAB_3361|M.abscessus_ATCC_1997 QSKYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAESRVGAFG MSMEG_3290|M.smegmatis_MC2_155 AAKAEAGAFESAQDLLAMVEATSLSDLQQAQVDVLRARLAFVTSHG---- MMAR_0085|M.marinum_M MTSLEAGMPDSATRLVASAAAAADDELIAARCELIRAKIAFAASRG---- Mflv_1156|M.gilvum_PYR-GCK EHHVVAGDMRRAATLLEQALVDLRPGVLCAIALNLLAGVRMV-------- MUL_2555|M.ulcerans_Agy99 FVALQAAQLDEAERLLADAGLGGGASASALLISSFISLYRYG-------- MAV_2362|M.avium_104 EAVSWQGRGEEAGFVLAHAEPDGDDDWLIARWGCLRAANLFWG------- MLBr_02341|M.leprae_Br4923 AEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISG------- . . Mb0914c|M.bovis_AF2122/97 ----VGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAA-- Rv0890c|M.tuberculosis_H37Rv ----VGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAA-- TH_3225|M.thermoresistible__bu GPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAPSGA-- Mvan_5002|M.vanbaalenii_PYR-1 ARPLDETASQLLTAAASFEQLDGYVSREAYLEALAAAMFAGRLGDPGA-- MAB_3361|M.abscessus_ATCC_1997 SVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRGG-- MSMEG_3290|M.smegmatis_MC2_155 ----SDAPPLLLKAARRLGGIDPDRARAVYLDAMLAAMFAGRLATGAN-- MMAR_0085|M.marinum_M ----SDAPPLLLAAAQRMQRLDPSESRKAYLGAVLASILVGRMATDQHNS Mflv_1156|M.gilvum_PYR-GCK -------EDDYIRAVELLERARADADNDAVLVTTLLSLGFCLGMTGSFTA MUL_2555|M.ulcerans_Agy99 --------DVTATHRRLVERLQSADDLDGETLTRMVNLLLAVSMFAAD-- MAV_2362|M.avium_104 ----CGDAEAARREADTVKKRVSSEAGLHLIDALELSMAFFRGDVETTT- MLBr_02341|M.leprae_Br4923 -----------LDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELP Mb0914c|M.bovis_AF2122/97 APYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDL Rv0890c|M.tuberculosis_H37Rv APYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDL TH_3225|M.thermoresistible__bu LLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTA Mvan_5002|M.vanbaalenii_PYR-1 VPRIAAAASAALDRLPESARPVDALLRGIVARITGGVSAGAAPLRLAMDL MAB_3361|M.abscessus_ATCC_1997 AVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTL MSMEG_3290|M.smegmatis_MC2_155 LVEVAAAARSAPERSGA-AEVSDLLLDWLTAHYGRGYVAARSALGDVLSA MMAR_0085|M.marinum_M SPSVAKAASNAPAAPHP-PRALDVLLDGLVIRLTEGYVAAAPRLRSAIRE Mflv_1156|M.gilvum_PYR-GCK QLATVREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLRAVDL MUL_2555|M.ulcerans_Agy99 -PALWQITDGLVDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDR MAV_2362|M.avium_104 ELGPGLCESDAVPMATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSC MLBr_02341|M.leprae_Br4923 RLDPDARRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAV Mb0914c|M.bovis_AF2122/97 ADTIGDRFVSR-------HCSLWLSLAQMWAGNLTEALELSREITAEAEA Rv0890c|M.tuberculosis_H37Rv ADTIGDRFVSR-------HCSLWLSLAQMWAGNLTEALELSREITAEAEA TH_3225|M.thermoresistible__bu MCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARD Mvan_5002|M.vanbaalenii_PYR-1 MQEQARNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRARD MAB_3361|M.abscessus_ATCC_1997 IRCEADRPAN--TSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIARE MSMEG_3290|M.smegmatis_MC2_155 FDGEADDLPLN--------RMLLASTAAHYAWDDVRLDVFTAHHVERARA MMAR_0085|M.marinum_M YLRERDIGVAE------PGWHDLTARVCLDLFDQDAYNFLAARQVEDLRA Mflv_1156|M.gilvum_PYR-GCK EDPEDNTPIPFR-------ASAARGLSLALTGRLAEADGQLAAVAQRSAQ MUL_2555|M.ulcerans_Agy99 LAELEPWDVMR------------VALAGYYVDLIDDFRSVLVPLADREIE MAV_2362|M.avium_104 GMGLHRFNIGIS-----------EIIAATDAGDDRAAERIYKRYAAMAEG MLBr_02341|M.leprae_Br4923 IPQTRSMALVT-----------YRPEYHGALRHVVGAQIIAVAPLSDVET Mb0914c|M.bovis_AF2122/97 SNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYA Rv0890c|M.tuberculosis_H37Rv SNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYA TH_3225|M.thermoresistible__bu AGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYH Mvan_5002|M.vanbaalenii_PYR-1 AGALEALPQVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYTPVRYQ MAB_3361|M.abscessus_ATCC_1997 VGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATG-HAPIRYH MSMEG_3290|M.smegmatis_MC2_155 TGALSEVPIALNSRAIALLFFGDLDGAADAVDEIQAADDATG-ALLAPYA MMAR_0085|M.marinum_M AGALTMLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATG-APPRPAI Mflv_1156|M.gilvum_PYR-GCK RGAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMVIAFS MUL_2555|M.ulcerans_Agy99 GGAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQL MAV_2362|M.avium_104 LPGAEAMVDAMLG--VVRLARGEFPAACAAFTRSISLFAKGFPSPWLVVV MLBr_02341|M.leprae_Br4923 STLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGERG Mb0914c|M.bovis_AF2122/97 AMTYAALAAG--DVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGG Rv0890c|M.tuberculosis_H37Rv AMTYAALAAG--DVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGG TH_3225|M.thermoresistible__bu RLIIAAWRG---DAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNG Mvan_5002|M.vanbaalenii_PYR-1 TLTLAAWRG---EPADAEAVIEAAIADANARGEGRVLGAADYAFAVLYNG MAB_3361|M.abscessus_ATCC_1997 SLILAAWRG---SEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNS MSMEG_3290|M.smegmatis_MC2_155 EVGLAAMRG---DLARTASLVDATVAAVTARGEGNGLTVAWWAEAVLHNG MMAR_0085|M.marinum_M KTYLAAYRG---QEQICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNG Mflv_1156|M.gilvum_PYR-GCK ICAAVAAYRG--REDQARDQAAGALAQGGDYVALTVWASATLAFLEVSR- MUL_2555|M.ulcerans_Agy99 RGYLGVISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFA MAV_2362|M.avium_104 GAFQAQAEGAR-GDSTAAAAALWRADRAYGPHAAVFLPELELARAWERAA MLBr_02341|M.leprae_Br4923 RYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDL Mb0914c|M.bovis_AF2122/97 DAIAARQFANDAVDATN-----------GWHRMVALTIRARVATARGEPE Rv0890c|M.tuberculosis_H37Rv DAIAARQFANDAVDATN-----------GWHRMVALTIRARVATARGEPE TH_3225|M.thermoresistible__bu IGRYREALAAARTTCEY-EDLG----FYSWCLHELVEAAARVGETDTAHR Mvan_5002|M.vanbaalenii_PYR-1 LGRYQEACSAARRACEY-EDLG----VHSWVLAELVEAADHCGDTALAVS MAB_3361|M.abscessus_ATCC_1997 LGRYELAFMAARRACEH-EDLG----LYSWCLIELIEAAVRCGEHDTAVK MSMEG_3290|M.smegmatis_MC2_155 FGSARKALEAASRAAAFPPELA----SANWALIELVEAATRCGAVETAAE MMAR_0085|M.marinum_M LGQYQEAFNAAASGARY-DDVG----MCGYLLGELIEAAVRCKEHNAATE Mflv_1156|M.gilvum_PYR-GCK -GNYEQALEAAEPLVDLYRDFPGTELMSACFMPDAIESLIAVGRLDEAEP MUL_2555|M.ulcerans_Agy99 EGDYESAYLQATAITAP-GEFPPLALHATRTLFDLVEAAVHTDRLNEARR MAV_2362|M.avium_104 AGDTQAATTHATQAAEIARAAG---------MHAAEMRTRHAAVRFGDRS MLBr_02341|M.leprae_Br4923 LASLGIDLSVDELIDAN--------------LVDQVRFTAPVEYAFRHPL . Mb0914c|M.bovis_AF2122/97 LARDDAHAALACGAELHIYQGMPDAMELLAGL----AGEVGSHSEGVRLL Rv0890c|M.tuberculosis_H37Rv LARDDAHAALACGAELHIYQGMPDAMELLAGL----AGEVGSHSEGVRLL TH_3225|M.thermoresistible__bu ALGDIEERAGASGTPWGLGALAGARALLADGD----EADRLFREALDHLS Mvan_5002|M.vanbaalenii_PYR-1 ALERLQERTADTGTDWGLGTLAGAQALVADDD----HAEALFEESIDRLA MAB_3361|M.abscessus_ATCC_1997 AFGQLEERALAAQSDWSQGMVARSRALITVGH----DAEPHYREAIQRLT MSMEG_3290|M.smegmatis_MC2_155 AAADLAELTTSSGTDWALGLAARARALVSGPA----ESERWYLESIERLE MMAR_0085|M.marinum_M ALGRLLKRTKASGTPTALGIGASATALVSDGS----IADAAYREAITHLR Mflv_1156|M.gilvum_PYR-GCK LIAAFERNGAELDRPWQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHA MUL_2555|M.ulcerans_Agy99 HVRAAKRLQFADAPPRLAIATGAAEALCASDE----RAPALFEKVLGHPA MAV_2362|M.avium_104 QTARLERLARILDTPLAEAAADHARGLTQRDG-------DLLDAAAQQFA MLBr_02341|M.leprae_Br4923 IRTVAYESQLKSDRARLHRRLAAAIEARAPHS-----VDQHAVLIAEHLE . . Mb0914c|M.bovis_AF2122/97 GAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALST Rv0890c|M.tuberculosis_H37Rv GAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALST TH_3225|M.thermoresistible__bu RSRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAER Mvan_5002|M.vanbaalenii_PYR-1 RTRVAVHLARAHLRYGEWLRRALRRNDAREQLTLASGMFTRFGAAAFAER MAB_3361|M.abscessus_ATCC_1997 NTRISAHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAER MSMEG_3290|M.smegmatis_MC2_155 NTRARAELARSRLVYGEWLRRERRRTAARSELRTAHEMFSAMGMSAFAAR MMAR_0085|M.marinum_M RSPVAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAER Mflv_1156|M.gilvum_PYR-GCK RLPMPFERARSALTLGEVLRRLRRR-DAAAAVRDALAQFEELGVPLWVAR MUL_2555|M.ulcerans_Agy99 VASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQR MAV_2362|M.avium_104 DLGALACAADAAAQAAGEHARRGDRGKKFESSAWAHALASRYELHTPAVE MLBr_02341|M.leprae_Br4923 AAGDLHAAYGWHMRAAAWATN-----QDVRAARVSWEHATKIADALTAED Mb0914c|M.bovis_AF2122/97 DEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFV Rv0890c|M.tuberculosis_H37Rv DEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFV TH_3225|M.thermoresistible__bu SRRELIAVGEKVRRQPLTSGDE-LTAQEAQIAGLAADGLTNQEIGAQLFL Mvan_5002|M.vanbaalenii_PYR-1 TRRELIATGEKARRQPVTSGAQ-LTAQESQIARLAGDGLTNQEIGAQLFI MAB_3361|M.abscessus_ATCC_1997 AERELRATGAKVRKRSASSEKA-LTAQEAQIARMAGQGLTNQEIAAQLFI MSMEG_3290|M.smegmatis_MC2_155 AQRELAAAGDRIRETVIAAVDHRLTAQEAHIARLARDGLSNPEIGARLFI MMAR_0085|M.marinum_M ARRELSATGEAVYVQPTGITVD-LTTQESHIARLARDGYTNAEIAGLLFI Mflv_1156|M.gilvum_PYR-GCK ARIALSGLAVSG-----SAVGSELTDSERRIAELAASGMSNRDVAETLFV MUL_2555|M.ulcerans_Agy99 ARNELRAAGTAVRHSAAVGPAP-LTAQERLVAELAAKGLSNKEIAARLCL MAV_2362|M.avium_104 AAARPLP----------------FSGRERQIVNLVAAGLSNREIADRLVI MLBr_02341|M.leprae_Br4923 PHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATV : . . : : Mb0914c|M.bovis_AF2122/97 SPRTVQTHLTHVYAKLGLASRVQLVDEAARRGSPS--------------- Rv0890c|M.tuberculosis_H37Rv SPRTVQTHLTHVYAKLGLPSRVQLVDEAARRGSPS--------------- TH_3225|M.thermoresistible__bu SVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW---------------- Mvan_5002|M.vanbaalenii_PYR-1 STHTVDWHLRKVFVKLGITSRRQLRSASWAS------------------- MAB_3361|M.abscessus_ATCC_1997 SSHTVEWHLRKVFAKRGITSRRQLRSGR---------------------- MSMEG_3290|M.smegmatis_MC2_155 SARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR---------------- MMAR_0085|M.marinum_M SARTVEWHLSKIFAKLGVTSRRELRAILMESP------------------ Mflv_1156|M.gilvum_PYR-GCK SVKTIETNLSRVYRKLGIRSRAQLGRMLR--------------------- MUL_2555|M.ulcerans_Agy99 SPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI------------ MAV_2362|M.avium_104 SVRTVEGHLYRLFTKLGINSREQLTLLVAREPRGRRELLGHSNPSLGDQD MLBr_02341|M.leprae_Br4923 GPAIDHVYQDRLH------------------------------------- . ::. Mb0914c|M.bovis_AF2122/97 ------- Rv0890c|M.tuberculosis_H37Rv ------- TH_3225|M.thermoresistible__bu ------- Mvan_5002|M.vanbaalenii_PYR-1 ------- MAB_3361|M.abscessus_ATCC_1997 ------- MSMEG_3290|M.smegmatis_MC2_155 ------- MMAR_0085|M.marinum_M ------- Mflv_1156|M.gilvum_PYR-GCK ------- MUL_2555|M.ulcerans_Agy99 ------- MAV_2362|M.avium_104 DVHPHAG MLBr_02341|M.leprae_Br4923 -------