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MFLSAPAFRVEPTRSRHSALRWARHRRFADGPRWQMLRSLQIADQIARTGHMPVRRLDLIWISARNAARR ELDLGVAALVEAVTLLTADVEGSTRLSQTRLNELAADYPTLDQNISEAVAAHGGVTRPVDQEVGSGLVVA FLRAGDAIACALELQLSTLAPMRPRVGVHTGDVRLRGDGTITGSAINESACLRDLAHEGQTLLSAATGDL VIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRDLRNEFPPLRMSVGNRSSLPAQFTTFVGRDAQINEV QEVLTNYRLVTLRGEGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHALGLIDRPGSSTF DTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPELSILATSRESIGVTGEVTWVVPSLSPANEAI QLFTERARLVQPNFEIVADNFDAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGARS TVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAGGDDFVERYSVLDQLTLLVDKS LVVAEESRGSTRYRLLETVRQYALEKLNESEEIDGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEI DNLRAAFTWSRGNGDIAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLVPAGVWARALAEKVIL KAWPATSPMGAPDIVAQAHHALALARDAGDCAVLARALVACGCGSGCDTEAAQPYFAEAIELARAINDEW TLSQIDYWQVVGIFISGQPIPLRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANGALALSRDVT AEAEVANDVVTKVLGLYVEAMALSYIGDSAARTIAGAALEAATELGGIYQDLGYGAITRAALAAGDVAAI EASEASWDLRNQHNVVTAHHELMAQAALVRGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELG KARDDAHAAVACGVGVQTYLAMPDALELLAGLAGEAGNHGQAVRLFGAAAAQRQRTGEVRHKIWDAGYEA ATAALRDAMGDEDFTAAWAEGAAAPLDEAIAYAQRGRGERKRPSNGWDALTPAEHKIVKLVTEGLVTKDI AARLFVSPRTVQTHLTHIYTKLDVTSRVQLVQEAAQHST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1358 | - | - | 100% (1159) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. tuberculosis H37Rv | Rv0890c | - | 0.0 | 65.50% (884) | LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0386 | - | 0.0 | 53.45% (1087) | LuxR/UHPA family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1393 | - | 0.0 | 99.83% (1159) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4504 | - | 7e-14 | 25.54% (603) | regulatory protein, LuxR |
| M. leprae Br4923 | MLBr_01753 | - | 0.0 | 58.12% (1084) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3361 | - | 1e-08 | 39.53% (86) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0123 | - | 0.0 | 51.85% (1107) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_2362 | - | 8e-12 | 23.81% (945) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0545 | - | 3e-18 | 38.92% (167) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3225 | - | 8e-13 | 27.95% (508) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2743 | - | 2e-98 | 33.81% (846) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 0.0 | 53.13% (1086) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1358|M.tuberculosis_H37Rv MFLSAPAFRVEPTRSRHSALRWARHRRFADGPRWQMLRSLQIADQIARTG
Mb1393|M.bovis_AF2122/97 MFLSAPAFRVEPTRSRHSALRWARHRRFADVPRWQMLRSLQIADQIARTG
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVAR-----------LRSTDVPTDLHRG-
MMAR_0123|M.marinum_M --MLASMSEIDPRAEAPLVD----------------WSDVDMGELLPTG-
Mvan_5928|M.vanbaalenii_PYR-1 -----------------------------------------MSELVPTG-
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 -----------------------------------------MTEKLSTG-
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --MSSRDGDVVLHG------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --MRAALPAAMMNAMSDASP------------------------------
MAV_2362|M.avium_104 --------------------------------------------------
Rv1358|M.tuberculosis_H37Rv HMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGSTRLSQTR
Mb1393|M.bovis_AF2122/97 HMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGSTRLSQTR
MLBr_01753|M.leprae_Br4923 ------------------------------CTVTLFLGDVEGLAELSETQ
MMAR_0123|M.marinum_M -------------------------------TVTLLLADVEGSTRLWQNQ
Mvan_5928|M.vanbaalenii_PYR-1 -------------------------------TVTLLLADVQGSTQLWETQ
MUL_2743|M.ulcerans_Agy99 --------------------------------MTFLFTDVEGSTRLWESD
MSMEG_0545|M.smegmatis_MC2_155 -------------------------------TKTLLMARVDRAEELWQTE
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu ----------------------------RAAEIATLRDVMSTARAGSSRV
Mflv_4504|M.gilvum_PYR-GCK -----------------------------QAADDPQVAGFLCTATSAPTG
MAV_2362|M.avium_104 -----------------------------MGREAELRRSLAALSNAEFHG
Rv1358|M.tuberculosis_H37Rv LNELAADYPTLDQNISEAVAAH--GGVTRPVDQEVGSGLVVAFLRAGDAI
Mb1393|M.bovis_AF2122/97 LNELAADYPTLDQNISEAVAAH--GGVTRPVDQEVGSGLVVAFLRAGDAI
MLBr_01753|M.leprae_Br4923 PDEAADAIARLDCVVSEAVAAH--GGVQQVVQGVRGN-FLATFARASDAT
MMAR_0123|M.marinum_M PEPMTAAVAHLDSVLATTVATH--HGVR-PVEQGEGDSFVVAFASAREAI
Mvan_5928|M.vanbaalenii_PYR-1 PETMTAAVAQLDRTLTDLVSDH--DGVR-PVEQGEGDSFVVAFTRASDAV
MUL_2743|M.ulcerans_Agy99 PDRMRAALAAHDAVLTRTIQTH--RGWLFKHTG---DGVCAAFASPRSAV
MSMEG_0545|M.smegmatis_MC2_155 LDQTIAAIPWLRASMAHLIALN--DGTLQRDAS---DSFVAAFDRASDAV
MAB_3361|M.abscessus_ATCC_1997 -MLRGQAGVGKTALLRYVLGKA--SGQLIAQASGIQSEMELAFAGLQQFC
TH_3225|M.thermoresistible__bu LVLHGEAGVGKTALLGQLLGDA--AGMRCVQVAGVESDMELAYAGLHQLC
Mflv_4504|M.gilvum_PYR-GCK LIIEGDAGIGKTTLWLSLLQTARMRGFQVLTARVGQAESVMAFAALADLL
MAV_2362|M.avium_104 VALVGDAGVGKSTLARMLAKTVESAGRTVRFALGTQTGSAVPLGAFSHAV
* .
Rv1358|M.tuberculosis_H37Rv ACALELQLSTLAPMRPRVGVHTGDVRLRGDGT---ITGSAINESACLRDL
Mb1393|M.bovis_AF2122/97 ACALELQLSTLAPMRPRVGVHTGDVRLRGDGT---ITGSAINESACLRDL
MLBr_01753|M.leprae_Br4923 ACALDLQLAPIVPVRFRIALHTGEVQISNDDVN--NVVFMMVQAAGLLDL
MMAR_0123|M.marinum_M ACALDLQRSPLGPIRLRIGVHTGDIQLRDPNDPTNYIGPTINRTARIREL
Mvan_5928|M.vanbaalenii_PYR-1 ACALALQRAPLAPIRLRIGVHTGEVRLRDEG---NYVGPTINRTARLREL
MUL_2743|M.ulcerans_Agy99 DAAVDAQRALELPVR--MGLATGEAEPHDAD----YFGAVLNRAARVMAT
MSMEG_0545|M.smegmatis_MC2_155 MCALDLQLAPLEPFALCIGVHAVEHTDSADS----------DGAARLRDI
MAB_3361|M.abscessus_ATCC_1997 APLTKYSGAIPDPQREALTIAFGTRSGPPPDR-----FLIGLAVLSLLAA
TH_3225|M.thermoresistible__bu APLLDRLDDLPSPQRDVLNVAFGRGAGPAPGR-----FLVGLAVLNLLAA
Mflv_4504|M.gilvum_PYR-GCK GAVSDEHFAALPPLQRLALDRVLLRAGADGPAT--DQRVVAAGFVSLLHI
MAV_2362|M.avium_104 SLMAVNEPAVMLAAAHNTLSQDKN------------LVVVVDDAQLLDPL
. :
Rv1358|M.tuberculosis_H37Rv AHEGQTLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRD
Mb1393|M.bovis_AF2122/97 AHEGQTLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCHRD
MLBr_01753|M.leprae_Br4923 ACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLCHRN
MMAR_0123|M.marinum_M AHGGQTVISGATQLLVVDQLPDGAWLADLGLHPLRDLPRPERVMQLCHSG
Mvan_5928|M.vanbaalenii_PYR-1 AHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQLCHAD
MUL_2743|M.ulcerans_Agy99 GHGGQILLTDSTANLIS-----GVDLLDLGSRRLRDLPAPVRVFQVRAPG
MSMEG_0545|M.smegmatis_MC2_155 ARGGQTLISAAAAALVSARMPAHAALT-----PLRDRVRHEPVYQLNHPG
MAB_3361|M.abscessus_ATCC_1997 AAEHQPVLCVIDDAQWLDR----VSLQTLAFVTRRLGSEPVAMLFAVRDG
TH_3225|M.thermoresistible__bu AGADQPLLCVIDDAQWLDR----VSLQTLGFVARRLMAEPVAMVFALRDD
Mflv_4504|M.gilvum_PYR-GCK LAADAPVLIAIDDVQWLDAS--SRTAIEFAVRRLKGAFGVVVTERCVPGD
MAV_2362|M.avium_104 SATLVNQLAAWRSARLIVTIRSGEPVLDAVTALLKERLLLTVHVDPFTRE
: :
Rv1358|M.tuberculosis_H37Rv LRNEFPPLRMS-VGNRSSLPAQFTTFVGRDAQINEVQEVLTNYRLVTLRG
Mb1393|M.bovis_AF2122/97 LRNEFPPLRMS-VGNRSSLPAQFTTFVGRDAQINEVQEVLTNYRLVTLRG
MLBr_01753|M.leprae_Br4923 LRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLTLVG
MMAR_0123|M.marinum_M LQNDFPPLRTTKSIAVHRMPARLTRFVGRIAQMADVRSLLADNRLVTLTG
Mvan_5928|M.vanbaalenii_PYR-1 LSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANRLVTLTG
MUL_2743|M.ulcerans_Agy99 LRTDFPALRAPDTSPG-NLRPALTSFVARAAEIGQVQTALQVHRLVTLTG
MSMEG_0545|M.smegmatis_MC2_155 LR----------------------------TEADEVPHLPYG-RVVR---
MAB_3361|M.abscessus_ATCC_1997 TDSELAGLPELTVHG-------LRAADAGTLLDSVIPGLLDERVRDRIVA
TH_3225|M.thermoresistible__bu IHEALVGVPALAVPG-------LADADARTLLEHMFPGAIDANVRDRLVA
Mflv_4504|M.gilvum_PYR-GCK GTTAGWLTLERPDGLIRVSVPPMDAGRLHALISHRLGRTLTRPVVLRIAE
MAV_2362|M.avium_104 QTELLAGTVLGGPVDPWVVDELLQRSSGNPLLLRGFLTAGRDTGALFRTA
.
Rv1358|M.tuberculosis_H37Rv EGGVGKTRLAIQIAA--ASEFRDGLCFVDLAPIADPGMVSTTAAHALGLI
Mb1393|M.bovis_AF2122/97 EGGVGKTRLAIQIAA--ASEFRDGLCFVDLAPIADPGMVSTTAAHALGLI
MLBr_01753|M.leprae_Br4923 PGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT--------
MMAR_0123|M.marinum_M AGGAGKTRLAVEIAASAVDEFGDGLWYVDLAPVSHAEAVPVTVARALGLS
Mvan_5928|M.vanbaalenii_PYR-1 AGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAITVARALGLP
MUL_2743|M.ulcerans_Agy99 VGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDAVAAVLGIT
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ETQGNPLALLELPRDMTAEELAGGFGWPDGGRLAG---------------
TH_3225|M.thermoresistible__bu ESRGNPLALLEVPRTYAVGELAGGFVSPGAGSAPS---------------
Mflv_4504|M.gilvum_PYR-GCK MSGGNPFYALELAHTHVNSGDSPPAAEPPLPATLADVVR-----------
MAV_2362|M.avium_104 EGWQLRGPLRGDRELHDALEYRLQSLSSEER-------------------
Rv1358|M.tuberculosis_H37Rv DRPGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAEL-VVELLGACPELS
Mb1393|M.bovis_AF2122/97 DRPGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAEL-VVELLGACPELS
MLBr_01753|M.leprae_Br4923 ------VLDNLRRCIGDRRMLMVLDNCEYLLDVCANV-MTTLLGACPSLT
MMAR_0123|M.marinum_M DQPGRSTVDALARFIGEHQVLVVLDNCEHLLDATAAL-LLELTGRCPAVR
Mvan_5928|M.vanbaalenii_PYR-1 DQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATL-IDALLGACPALA
MUL_2743|M.ulcerans_Agy99 QQAGKTVTQSVATALERRVRLLVFDNCEHVRDAAADL-IEAILAGSTTVR
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -QIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTLLARAAQQLGIPMHAI
TH_3225|M.thermoresistible__bu -RIEENYVHRIRALPAQTRRLLLIAAAEPIGDSALFLRAAALMGIAVDAL
Mflv_4504|M.gilvum_PYR-GCK ------RRVGLLDDATRTLLLGVACVADPTVELLARAHGASTDEITAGLE
MAV_2362|M.avium_104 ------EVVEILATAGLLNWDILRDICDAEAVAALERRGLIRLVTDGSHA
Rv1358|M.tuberculosis_H37Rv ILATSRESIGVTGEVTWVVPSLSPAN----EAIQLFTERARLVQPNFEIV
Mb1393|M.bovis_AF2122/97 ILATSRESIGVTGEVTWVVPSLSPAN----EAIQLFTERARLVQPNFEIV
MLBr_01753|M.leprae_Br4923 ILATSREPIGVAGEVIWRVSMLSPAD----EAVELFTERAALVQPGFSVT
MMAR_0123|M.marinum_M LLATSREPLGVPGEVTFLVPSLSVT-----EATELFTDRARRVRPDFAVT
Mvan_5928|M.vanbaalenii_PYR-1 MLATSREPIAVAGEQTWRVPPLALDD----DAIELFTDRARRARPDFIIS
MUL_2743|M.ulcerans_Agy99 ILATSRERLEVPDEQLWSVPSLDVGGGVVSAAGTLFVERAQSVAPGFAPT
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 APAEAADLVELSTRVRFRHPLVRSAVYISANPLERRRIHGVLAGATDPGA
TH_3225|M.thermoresistible__bu APAEAARVIQFGPRMRFFHPLMRSAAYRAADPRDRRAVHRALAEATDPGA
Mflv_4504|M.gilvum_PYR-GCK RAEAAGIVVLEGNRVRFTHPLLAGGVYTDAGPTARRAMHRAIAS---VES
MAV_2362|M.avium_104 VAQLTHPMLG---EAATRHAGMVRTRQLNGKLARALQKHERTGSRHLRLP
Rv1358|M.tuberculosis_H37Rv AD-NFDAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTG
Mb1393|M.bovis_AF2122/97 AD-NFAAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTG
MLBr_01753|M.leprae_Br4923 DG-NRQIVTEICQRLDGMPLAIELAAARIRTLSLTEIADGLDDRFRLLTG
MMAR_0123|M.marinum_M DD-NTTAVTEICNRLDCMPLAIELAAARVRALSIDEIRTGLHDRFRLLTG
Mvan_5928|M.vanbaalenii_PYR-1 AD-DAAAVSEICHRLDGMPLAIELAAARVRALSLTEIVDGLHDRFRLLTG
MUL_2743|M.ulcerans_Agy99 DAQDAAAIGEICRRLDGIPLAIELAASRMASMTPIEVRDRLDHRFRLLVG
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 DPDRRAWHRAHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATEL
TH_3225|M.thermoresistible__bu DPDRRAWHAANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVL
Mflv_4504|M.gilvum_PYR-GCK HPELRARHLALAASSGDDEIFAALDQAADSARARGAPAAAAELMDLALGL
MAV_2362|M.avium_104 HLQSRIRLAEFMLHSDMEPDLDVITEAARDALAMSNVQLGEELAR--FAL
Rv1358|M.tuberculosis_H37Rv GARSTVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVA
Mb1393|M.bovis_AF2122/97 GARSTVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVA
MLBr_01753|M.leprae_Br4923 GARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTFDLKVA---Y
MMAR_0123|M.marinum_M GARTVVRRQQTLRASVDWSHALLTEPERVLFRRIAVFLGGFDLDAA---Q
Mvan_5928|M.vanbaalenii_PYR-1 GSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAVFAGGFDLDGA---Q
MUL_2743|M.ulcerans_Agy99 -SRRGLGRHQTLRHAVAWSYDHLSDAEKVLLERCSVFAGGFDLQSAC--A
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 TADPAARGRRALAAAQSKYDAAAFDAARELLGVADMTP----------LD
TH_3225|M.thermoresistible__bu TADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERAP----------LS
Mflv_4504|M.gilvum_PYR-GCK GAHDPMRR---LKAAENHFLAGDTAKAAAALG------------------
MAV_2362|M.avium_104 DRGGGLPAALVLAEAVSWQGRGEEAG------------------------
Rv1358|M.tuberculosis_H37Rv AAGGDDFVERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEK
Mb1393|M.bovis_AF2122/97 AAGGDDFVERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEK
MLBr_01753|M.leprae_Br4923 AVGHDDLEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKK
MMAR_0123|M.marinum_M AVAGDSQVQRYQVVDELALLVDKSLVIAESGGGPTRYRLLETVRQYAQEK
Mvan_5928|M.vanbaalenii_PYR-1 AITVDGEVHRYEVVDLLTLLVDKSLLIAENTAGRTRYRLLETVRQYAQEK
MUL_2743|M.ulcerans_Agy99 VAGSADTHDDYEVLDLLDALVGKSLLIVDRLSGRSRFSMLETIREFAEEQ
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 PLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNL
TH_3225|M.thermoresistible__bu ALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPA
Mflv_4504|M.gilvum_PYR-GCK ---------EVGSIEPPILRAMATSLLATVRMYDNEHRQAVDLLRSALDD
MAV_2362|M.avium_104 -----------FVLAHAEPDGDDDWLIARWGCLRAANLFWGCGDAEAARR
Rv1358|M.tuberculosis_H37Rv LNESEEIDGVRARHRTHYATMAAGLNVPASTD-YEQRLLQAEAEIDNLRA
Mb1393|M.bovis_AF2122/97 LNESEEIDGVRARHRTHYATMAAGLNVPASTD-YEQRLLQAEAEIDNLRA
MLBr_01753|M.leprae_Br4923 LEESNEVDLVLARHRDHYMALGALLDTPGDID-HEQLVEQVETELDNLRS
MMAR_0123|M.marinum_M LAESGEVEAVRSRHVTYYKSVAKLLDAPTGTD-HERRLAQAEDELDNLRS
Mvan_5928|M.vanbaalenii_PYR-1 LGESGEADTLRARHRDHYTARAAELDAPSVAG-HERRLNQTDIEMDNLRA
MUL_2743|M.ulcerans_Agy99 LVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEAYTWLTAELANLRL
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ARETYLDAVGAAMYGGRLCPRGGAVEVAEPARLAPAGAQP-ARPSDLLLD
TH_3225|M.thermoresistible__bu ARESYLEAFAALMYAGRLAPSGALLEAADAVQAAFARAPEGSRAVDAFCQ
Mflv_4504|M.gilvum_PYR-GCK AADNVPVQVQVLLRLSFALNSIGELDDARRYARDAVKLAEELGFPGATSA
MAV_2362|M.avium_104 EADTVKKRVSSEAGLHLIDALELSMAFFRGDVETTTELGPGLCESDAVPM
Rv1358|M.tuberculosis_H37Rv AFTWSRGNGDIAAALQLASALQP-LWS-QGRMREGLAWLESILE------
Mb1393|M.bovis_AF2122/97 AFTWSRGNGDIAAALQLASALQP-LWS-QGRMREGLAWLESILE------
MLBr_01753|M.leprae_Br4923 AFAWSRETGDIAGALQLASSLQP-IWFGRGHMYEGLAWFDSIFE------
MMAR_0123|M.marinum_M AFGWSLETRDFDSALELATSLHP-VWMTRGQGREGLAWLEAGLGNEAGLG
Mvan_5928|M.vanbaalenii_PYR-1 AFAWSRENANTDHSLLLASSLHP-LWRARGRLQEGQAWFDAALT-----D
MUL_2743|M.ulcerans_Agy99 AFRWTADNNDLDDAASIATWVGF-LGFLVNRFEP-LTWVEEAIE------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GLARRITHGAAASAQTLGEALTLIRCEAD-RPANTS-WMEQAFP------
TH_3225|M.thermoresistible__bu GMTQRIVGGISAAAAPLRVALTAMCELARSRPAEVVHWLVPAFP------
Mflv_4504|M.gilvum_PYR-GCK ALAWAVHVDFQCGRGLDETALARAMKLYDSTFDVPIIFRAPFVH------
MAV_2362|M.avium_104 ATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSCGMGLHRFN------
Rv1358|M.tuberculosis_H37Rv ---REGDNHLVP-AGVWARALAEKVILKAWPATSPMGAPDIVAQAHHALA
Mb1393|M.bovis_AF2122/97 ---REGDNHLVP-AGVWARALAEKVILKAWPATSPMGAPDIVAQAHHALA
MLBr_01753|M.leprae_Br4923 ---HKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALT
MMAR_0123|M.marinum_M NEAGLGNEDVQVSPSTLARALADKVTLLAWTGSMAG-----FDDAERALT
Mvan_5928|M.vanbaalenii_PYR-1 YEARPG----EADPAVYARALADRAFMDGHVGITDR-----LDQAQKALA
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2362|M.avium_104 --------------------------------------------------
Rv1358|M.tuberculosis_H37Rv LARDAGDCAVLARALVACGCGSGCDTEAAQPYFAEAIELARAINDEWTLS
Mb1393|M.bovis_AF2122/97 LARDAGDCAVLARALVACGCGSGCDTEAAQPYFAEAIELARAINDEWTLS
MLBr_01753|M.leprae_Br4923 MAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELARTQGDKWTLS
MMAR_0123|M.marinum_M IARELADPALLIRALVARGVITAYDADVARPYFDEAAQLARELGDSWRLS
Mvan_5928|M.vanbaalenii_PYR-1 MARDIDDPALLVRALTACGGLAAYNADVARPLLAEAVDLARSMGDKWMLA
MUL_2743|M.ulcerans_Agy99 --RAVDHPKLAFLHVLASQCYTTGRVQEAIRYADEAARLLATDRYEVPFG
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -------------IALESATHEVWDDDMWHHLATRAVHIAREVGALSLLP
TH_3225|M.thermoresistible__bu -------------VLQESAGHELWDENLVDALSEAVVRQARDAGALAGLP
Mflv_4504|M.gilvum_PYR-GCK ----------------ALAMSWTGRLEQAHQELTAVRGVCLERGAESDMM
MAV_2362|M.avium_104 -----------IGISEIIAATDAGDDRAAERIYKRYAAMAEGLPG--AEA
Rv1358|M.tuberculosis_H37Rv QIDYWQVVGIFISG-QPIPLRAAAEQARELADSIGNRFVSRQCRLFACLA
Mb1393|M.bovis_AF2122/97 QIDYWQVVGIFISG-QPIPLRAAAEQARELADSIGNRFVSRQCRLFACLA
MLBr_01753|M.leprae_Br4923 QIRLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIA
MMAR_0123|M.marinum_M QILSLQTRAAMAAG-DPIALEAAGEEGLRIAEAIGDRTTSRECRGALGWV
Mvan_5928|M.vanbaalenii_PYR-1 ETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRICGWLLGIA
MUL_2743|M.ulcerans_Agy99 -IEGWPSGACTSSG---HPEQSVELCRTQLALGHDTHTLTLGC---LVLA
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AALIYRAGMHVHAG----ELDAAAELVQEADAISAATGH-APIRYHSLIL
TH_3225|M.thermoresistible__bu QALVYRAGVHLLFG----EFGLADTLLTEAESITAATDHRGPVRYHRLII
Mflv_4504|M.gilvum_PYR-GCK AIAGFLAINHLWRG-QITDAEAEAAEAVERAEQLGGDDVLIIPMTVRGAI
MAV_2362|M.avium_104 MVDAMLGVVRLARG----EFPAACAAFTRSISLFAKGFPSPWLVVVGAFQ
Rv1358|M.tuberculosis_H37Rv QIWEGDANGALALSRDVTAEAEVANDVVTKVLGLYVEAMALSYIG-DSAA
Mb1393|M.bovis_AF2122/97 QIWEGDANGALALSRDVTAEAEVANDVVTKVLGLYVEAMALSYIG-DSAA
MLBr_01753|M.leprae_Br4923 QLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHRD-VSAA
MMAR_0123|M.marinum_M RAWRGDPIGALHQLGEAIAEASAAHDLLLLMISQVVQGFTYAYVGDADGA
Mvan_5928|M.vanbaalenii_PYR-1 HHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLAQRGDTDAA
MUL_2743|M.ulcerans_Agy99 LTIKGQCDEAEQLADALIESAEATRNPAALCYALLAYGFTFRDTN-----
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLG-----
TH_3225|M.thermoresistible__bu AAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNGIG-----
Mflv_4504|M.gilvum_PYR-GCK AAYAGRVDDARADARWVLAAVRNRKASHIADWPGMTLCFLEESLG-----
MAV_2362|M.avium_104 AQAEGARGDSTAAAAALWRADRAYGPHAAVFLPELELARAWERAA-----
Rv1358|M.tuberculosis_H37Rv RTIAGAALEAATELGGIYQDLGYGAITRAALAAGDVAA-IEASEAS-WDL
Mb1393|M.bovis_AF2122/97 RTIAGAALEAATELGGIYQDLGYGAITRAALAAGDVAA-IEASEAS-WDL
MLBr_01753|M.leprae_Br4923 LVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHL
MMAR_0123|M.marinum_M CACADAVFTSSAELVGANEGLGYATAAIACQAAGDATAAWKAYQKARELV
Mvan_5928|M.vanbaalenii_PYR-1 RAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAASDSATRSF
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2362|M.avium_104 --------------------------------------------------
Rv1358|M.tuberculosis_H37Rv RNQHNVVTAH-HELMAQAALVRGDVTTARRFADEAVLASTGWHLMMALIA
Mb1393|M.bovis_AF2122/97 RNQHNVVTAH-HELMAQAALVRGDVTTARRFADEAVLASTGWHLMMALIA
MLBr_01753|M.leprae_Br4923 GADHGLVAIH-LELMAAVALARGDVIVARRLADNSVSATTGWHQMAALTT
MMAR_0123|M.marinum_M GMDPQMAGVFPFGALAPLVS--GDLSAARRWADDVVSTSYGCYLSVALTA
Mvan_5928|M.vanbaalenii_PYR-1 GPS-EVAGIQDPNVAAQIACTRGDLDTARSLVDGAVSITRGVHRASALTT
MUL_2743|M.ulcerans_Agy99 -----------------PASALAAMRRGLRIAQDTGNRNSETHLAAVLCR
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------RYELAFMAARRACEHEDLGLYSWCLIELIE
TH_3225|M.thermoresistible__bu --------------------RYREALAAARTTCEYEDLGFYSWCLHELVE
Mflv_4504|M.gilvum_PYR-GCK ----------------NHREALAALDDSFIAAGPPTTELMYAWHLPDAIE
MAV_2362|M.avium_104 -------------------------------AGDTQAATTHATQAAEIAR
Rv1358|M.tuberculosis_H37Rv RARVAIAQDELGKARDDAHAAVACGVGVQTYLAMPDALELLAGLA----G
Mb1393|M.bovis_AF2122/97 RARVAIAQDELGKARDDAHAAVACGVGVQTYLAMPDALELLAGLA----G
MLBr_01753|M.leprae_Br4923 RARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAELI----S
MMAR_0123|M.marinum_M RARVALAQGELGQADRDSHAALSCSAANGTTLGVADTLECLAELA----A
Mvan_5928|M.vanbaalenii_PYR-1 RARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLECLARVV----G
MUL_2743|M.ulcerans_Agy99 ---VEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLAVLAAFF----D
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVARSRALITVGH----D
TH_3225|M.thermoresistible__bu AAARVGETDTAHRALGDIEERAGASGTPWGLGALAGARALLADGD----E
Mflv_4504|M.gilvum_PYR-GCK AMVGVGRLDDAEILTAALERNGVEHDRRWMRAVGARCRAMLLAAHGDVAA
MAV_2362|M.avium_104 AAGMHAAEMRTRHAAVRFGDRSQTARLERLARILDTPLAEAAADH-----
Rv1358|M.tuberculosis_H37Rv EAGNHGQAVRLFGAAAAQRQRTGEVRHKIWDAGYEAATAALRDAMGDEDF
Mb1393|M.bovis_AF2122/97 EAGNHGQAVRLFGAAAAQRQRTGEVRHKIWDAGYEAATAALRDAMGDEDF
MLBr_01753|M.leprae_Br4923 QGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCKDF
MMAR_0123|M.marinum_M TEGDRREAARLLASAEAIRHRTGEVRLKILDAHCEVVLAELRNELGEQDF
Mvan_5928|M.vanbaalenii_PYR-1 DGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRDALGDKAF
MUL_2743|M.ulcerans_Agy99 RLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGDHAY
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCNRRSDARTELTAAHG
TH_3225|M.thermoresistible__bu ADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHG
Mflv_4504|M.gilvum_PYR-GCK AEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLRQKATAAKNLTDALH
MAV_2362|M.avium_104 ARGLTQRDGDLLDAAAQQFADLGALACAADAAAQAAGEHARRGDRGKKFE
Rv1358|M.tuberculosis_H37Rv TAAWAEGAAAPLDEAIAYAQRGRGERKRPSNGWDALTPAEHKIVKLVTEG
Mb1393|M.bovis_AF2122/97 TAAWAEGAAAPLDEAIAYAQRGRGERKRPSNGWDALTPAEHKIVKLVTEG
MLBr_01753|M.leprae_Br4923 DSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVSEG
MMAR_0123|M.marinum_M AAVWGQGAVISTDEVISYVRRGRGTRRRPSSGWGSLTPTEHDVVRLVQEG
Mvan_5928|M.vanbaalenii_PYR-1 EAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGLVSEG
MUL_2743|M.ulcerans_Agy99 ESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR-----------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 SFVNMGTAAFAERAERELRATGAKVRKRSASSEKALTAQEAQIARMAGQG
TH_3225|M.thermoresistible__bu MFTRMGAQGFAERSRRELIAVGEKVRRQPLTSGDELTAQEAQIAGLAADG
Mflv_4504|M.gilvum_PYR-GCK TFEQLGTPLWAQRARSELAR-------AVVAPAEGLTPSEQKVAEMAAAG
MAV_2362|M.avium_104 SSAWAHALASRYELHT--------PAVEAAARPLPFSGRERQIVNLVAAG
Rv1358|M.tuberculosis_H37Rv LVTKDIAARLFVSPRTVQTHLTHIYTKLDVTSRVQLVQEAAQHST-----
Mb1393|M.bovis_AF2122/97 LVTKDIAARLFVSPRTVQTHLTHIYTKLDVTSRVQLVQEAAQHST-----
MLBr_01753|M.leprae_Br4923 LDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN------
MMAR_0123|M.marinum_M LSNKDIAARMFISPRTVQTHLTHVYTKLGLTSRIQLVHEVARHA------
Mvan_5928|M.vanbaalenii_PYR-1 LSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT------
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR----------
TH_3225|M.thermoresistible__bu LTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW----
Mflv_4504|M.gilvum_PYR-GCK ATNKDIAAAMFISSKTVEHNLTRIYRKLGISSRAELGRRMDQPGL-----
MAV_2362|M.avium_104 LSNREIADRLVISVRTVEGHLYRLFTKLGINSREQLTLLVAREPRGRREL
Rv1358|M.tuberculosis_H37Rv -------------------
Mb1393|M.bovis_AF2122/97 -------------------
MLBr_01753|M.leprae_Br4923 -------------------
MMAR_0123|M.marinum_M -------------------
Mvan_5928|M.vanbaalenii_PYR-1 -------------------
MUL_2743|M.ulcerans_Agy99 -------------------
MSMEG_0545|M.smegmatis_MC2_155 -------------------
MAB_3361|M.abscessus_ATCC_1997 -------------------
TH_3225|M.thermoresistible__bu -------------------
Mflv_4504|M.gilvum_PYR-GCK -------------------
MAV_2362|M.avium_104 LGHSNPSLGDQDDVHPHAG