For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3225 | - | - | 100% (935) | regulatory protein, LuxR |
| M. thermoresistible (build 8) | TH_3931 | - | 2e-21 | 27.73% (649) | PUTATIVE putative regulatory protein, LuxR |
| M. thermoresistible (build 8) | TH_4413 | - | 4e-06 | 24.75% (691) | PUTATIVE putative response regulator receiver protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 1e-13 | 25.78% (547) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 8e-59 | 29.84% (955) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv2488c | - | 1e-13 | 26.01% (546) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 2e-16 | 25.89% (479) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 55.16% (892) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 0.0 | 45.22% (920) | transcriptional regulatory protein |
| M. avium 104 | MAV_2364 | - | 2e-09 | 24.83% (866) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 0.0 | 60.70% (916) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_2555 | - | 1e-29 | 33.02% (324) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 0.0 | 63.07% (918) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 -----------------------------------------------MSK
Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mvan_5002|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0321|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 LLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHDGVR
Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLDTT--AIAKLDRTLTELVREHRGVC
TH_3225|M.thermoresistible__bu ----------MSSRD-----GDVVLHGRAAEIATLRDVMSTARAGSSRVL
Mvan_5002|M.vanbaalenii_PYR-1 ------MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRTGASRSL
MSMEG_0321|M.smegmatis_MC2_155 ----------METGG-----RGQPLHGRAAECDALRRSIADVQSAQSRVL
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M -------------------MPTVTLVGRHREQQQLQQLLDAARRGESGVL
Mflv_1156|M.gilvum_PYR-GCK -------------------------------MKAVDDFLAGLQQLQPAGL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------MEFRRSLAALNNGEFHGV
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 PVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGEVAL
Rv2488c|M.tuberculosis_H37Rv PVEQGEGDSFLVAFARASDAVACA--LGLQRAPLAPIRLRIGMHTGEVSS
TH_3225|M.thermoresistible__bu VLHGEAG---VGKTALLGQLLGDA--AGMRCVQVAGVESDM-----ELAY
Mvan_5002|M.vanbaalenii_PYR-1 VLRGEAG---IGKTALLDHVVAQA--EGFRTTYVAGVESDM-----ELAF
MSMEG_0321|M.smegmatis_MC2_155 VLRGEAG---VGKTALLDFAAQHA--KGFRITQVAGVESDM-----ELAY
MAB_3361|M.abscessus_ATCC_1997 MLRGQAG---VGKTALLRYVLGKA--SGQLIAQASGIQSEM-----ELAF
MMAR_0085|M.marinum_M VLRGDAG---IGKTTLLTDLVDNA--PDLRVLRVRGAEMEM-----ELTY
Mflv_1156|M.gilvum_PYR-GCK LIEGEAG---IGKTTMLAGVVDAARQAGFRVLSAHGDQSGS-----GLAH
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 ALVGDGG---VGKSTLARMLAKTVESAGRTVRFALGTQTGW---------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 RDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKAWLV
Rv2488c|M.tuberculosis_H37Rv PDEGNCVG-PTIDRTARLRELAHGGQT--VLSGTTSDLVADLLPKDAWLN
TH_3225|M.thermoresistible__bu AGLHQLCA-PLLDRLDDLPSPQRDVLN--VAFGRGAGPAPGRFLVGLAVL
Mvan_5002|M.vanbaalenii_PYR-1 AGLHQLCA-PLLTHLDELPDPQRDALT--VAFGQGAGATPDRFLVGLAVL
MSMEG_0321|M.smegmatis_MC2_155 AGLQQLCA-PLMNNLDDLPEPQRDALA--VAFGLGVGQTPDRFLVGLAVL
MAB_3361|M.abscessus_ATCC_1997 AGLQQFCA-PLTKYSGAIPDPQREALT--IAFGTRSGPPPDRFLIGLAVL
MMAR_0085|M.marinum_M SGVQQLCG-PLMSLIGQLPEPQLDALE--IALGRKRGRAPDRLLLGLAVL
Mflv_1156|M.gilvum_PYR-GCK AAIADLFAGVQTDILDGLPELQRRAADGVLRRGDGTGGPTDERVIAAALL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 -------------------AVPLGAFSRAVSLGVGHEP-------AIMLA
MLBr_02341|M.leprae_Br4923 -------------------------------------------MTTALVC
Mb0393|M.bovis_AF2122/97 DLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFV
Rv2488c|M.tuberculosis_H37Rv DLGTYRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLV
TH_3225|M.thermoresistible__bu NLLAAAGADQPLLCVIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRD
Mvan_5002|M.vanbaalenii_PYR-1 SLMAAASTGGPLLCVIDDAQWLDQVSVQTLAFVARRLLAEPIAMVFAARD
MSMEG_0321|M.smegmatis_MC2_155 SLMAAAADEKPLLCIVDDAQWLDSVSVQTLAFVARRLLAEPVGLIFAVRD
MAB_3361|M.abscessus_ATCC_1997 SLLAAAAEHQPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRD
MMAR_0085|M.marinum_M TLVGEASRASPILCVVDDAQWVDSASVQALAFVARRIHVDPVAMVFATRD
Mflv_1156|M.gilvum_PYR-GCK GAVHGSATRTPVLVAVDDVQWLDPSSVAVLAFVARRVKG-RVGFVVAERP
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 AAHNTLGQDKNLVVVVDEAQLLDPLSATLVNQLAAGRSARLIVTIRSGEP
MLBr_02341|M.leprae_Br4923 VACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAV
Mb0393|M.bovis_AF2122/97 GRGAQITEVHRLVTDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGR-AWF
Rv2488c|M.tuberculosis_H37Rv GRVDEVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWY
TH_3225|M.thermoresistible__bu DIHEALVGVPALAVP----------GLADADARTLLEHMFPGAIDANVRD
Mvan_5002|M.vanbaalenii_PYR-1 TGAEALSGLPELAVP----------GLSDGEARDLLDSVVVGRLDDRVRD
MSMEG_0321|M.smegmatis_MC2_155 HGAPALAGLPELLVD----------GLSDTDARELLDSVILGRLDERVRD
MAB_3361|M.abscessus_ATCC_1997 GTDSELAGLPELTVH----------GLRAADAGTLLDSVIPGLLDERVRD
MMAR_0085|M.marinum_M RGPDALTGHCELSLQ----------GLEDHDARLVLSTAIPGRLNDSVAE
Mflv_1156|M.gilvum_PYR-GCK GVGPGLPAATWLQVGTGALTRLPVAPMSLGALHTMLSSRLGRRFSRPQIV
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 VLDAVTALLKERLLLT-----VHVDPFTREQTELLAGAVLGGPVDTRLVD
MLBr_02341|M.leprae_Br4923 GLERLREIMTELVSR-----------------AAGVIERYGGTVDKFTGD
Mb0393|M.bovis_AF2122/97 VDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNC
Rv2488c|M.tuberculosis_H37Rv VNLAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNC
TH_3225|M.thermoresistible__bu RLVAESRGNPLALLEVPRTYAVGELAG-----------------------
Mvan_5002|M.vanbaalenii_PYR-1 RIIAETRGNPLALLDLPHNHVGTELPG-----------------------
MSMEG_0321|M.smegmatis_MC2_155 RVVAETRGIPLALLEVPRTIPAAELAG-----------------------
MAB_3361|M.abscessus_ATCC_1997 RIVAETQGNPLALLELPRDMTAEELAG-----------------------
MMAR_0085|M.marinum_M TVLAEANGNPLALLELHNALIRGELAG-----------------------
Mflv_1156|M.gilvum_PYR-GCK RIAEVSGGNPLYALELARVADG----------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 ELFERSAGNLLLLRGFLTAGVESGALVHT---------------------
MLBr_02341|M.leprae_Br4923 GIMAIFGAP-----------------------------------------
Mb0393|M.bovis_AF2122/97 EHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSDEA
Rv2488c|M.tuberculosis_H37Rv EHLLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG-EA
TH_3225|M.thermoresistible__bu -------------------GFVSPGAGSAPSRIEENYVHRIRALPAQTRR
Mvan_5002|M.vanbaalenii_PYR-1 -------------------SAATPGSRPLARRLEQSYARRIKALPPQTQL
MSMEG_0321|M.smegmatis_MC2_155 -------------------GFSTIAGRRSAGRVEDSFTSRVRSLPDEARQ
MAB_3361|M.abscessus_ATCC_1997 -------------------GFGWPDGGRLAGQIEQTFLRRVQQLPAHTQT
MMAR_0085|M.marinum_M -------------------GYGLANATRTETQIERTFVSRLRALPSETKT
Mflv_1156|M.gilvum_PYR-GCK --------------------AGSRPGQRLPESLSELVRLRVDGLAEDVRD
MUL_2555|M.ulcerans_Agy99 --------------------------------MPALSANLVASIDRHPER
MAV_2364|M.avium_104 -----------------EQGWQLQGPLRGDRELHDALEYRLQSLSSEERE
MLBr_02341|M.leprae_Br4923 -----------------------------TALEDHALRACLAALGVQEKA
: : .
Mb0393|M.bovis_AF2122/97 VEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELAAARLRSMT
Rv2488c|M.tuberculosis_H37Rv IELFTDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALA
TH_3225|M.thermoresistible__bu LLLIAAAEPIGDSALFLR----------AAALMGIAVDALAPAEAARVIQ
Mvan_5002|M.vanbaalenii_PYR-1 LLLAAAAEPVGDAAVLIR----------AAAQLGIAVDMLTPAEAAGVIE
MSMEG_0321|M.smegmatis_MC2_155 LLLLAAAEPIGDAALFVR----------AAAHLGVAVPALAPAESAGLIE
MAB_3361|M.abscessus_ATCC_1997 LLLAAATDPLGDVTLLAR----------AAQQLGIPMHAIAPAEAADLVE
MMAR_0085|M.marinum_M FLLVAAAESTARPEWLWA----------AAHRLGIGPEAAAPAEAAGLIA
Mflv_1156|M.gilvum_PYR-GCK VLLVAASATSPTVDLLAK---------AVGVTPAAVTGLVEAAEVEGIVV
MUL_2555|M.ulcerans_Agy99 ITLRCDDLQSVFAELGAG-----------------------PGDRVAALP
MAV_2364|M.avium_104 VVEVLATAELLEWEILRD-----------ICDADAMASLERRGLIQLVTD
MLBr_02341|M.leprae_Br4923 RRLAAEVGDRDGVDLQLR---------------------------VGLNS
Mb0393|M.bovis_AF2122/97 LDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRR
Rv2488c|M.tuberculosis_H37Rv LTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRR
TH_3225|M.thermoresistible__bu FGPRMR-FFHPLMRSAAYRAADPRDRRAVHRALAEATDPGADPDRRAWHA
Mvan_5002|M.vanbaalenii_PYR-1 LGTRVR-FRHPLVRSAAYQAADLADRRTVHRALAEATDSATDPDRRAWHA
MSMEG_0321|M.smegmatis_MC2_155 FGTRIR-FHHPLVRSAAYRAASVEDRRAAHHALAEATDAVTDPDRRAWHA
MAB_3361|M.abscessus_ATCC_1997 LSTRVR-FRHPLVRSAVYISANPLERRRIHGVLAGATDPGADPDRRAWHR
MMAR_0085|M.marinum_M AQGSVR-FRHPLIRAAVYHSSSAAERRRVHAALAASIAGPDDDDHRVWHR
Mflv_1156|M.gilvum_PYR-GCK IDGNRIRFTHPVLANGIYAGADPQRRREVHRRLADLKT---DPELRARHL
MUL_2555|M.ulcerans_Agy99 GDRTRRRVCGPACELSGGRFRPSAR-----------------PQSCPGLT
MAV_2364|M.avium_104 GSHTLVQLNHPMLGEAATRHAGVVRSRQLNGILAKTLRKHLRAAGRRSQI
MLBr_02341|M.leprae_Br4923 GQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQT
.
Mb0393|M.bovis_AF2122/97 LAVF---VGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLVMADDNSG
Rv2488c|M.tuberculosis_H37Rv LAVF---PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDG
TH_3225|M.thermoresistible__bu ANGV---TGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPGL
Mvan_5002|M.vanbaalenii_PYR-1 ANAA---TGPDDAVAAELEASAARAQARGGVAAAAAFLERAAALTSDPAL
MSMEG_0321|M.smegmatis_MC2_155 ANAA---AGPSDAVATELEASAGRAQTRGGIAAAATFLERAAVLSADLHL
MAB_3361|M.abscessus_ATCC_1997 AHAA---AGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPAA
MMAR_0085|M.marinum_M AHAA---EAPDAQTADDLERSAERARARGGLSAAASFLEHATKLTPDPFV
Mflv_1156|M.gilvum_PYR-GCK ALAS---TVADETTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVS
MUL_2555|M.ulcerans_Agy99 EAAS---PGRSRGPLHLARCAAELTIRRGDACQAIELLRRAGELSDRPRR
MAV_2364|M.avium_104 SDPRGRIQLAQFIMRSDLEPDLDVVIKAAADAMAMSNVVLGEQLATFAVD
MLBr_02341|M.leprae_Br4923 AVLG--APQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELA
Mb0393|M.bovis_AF2122/97 RTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPSDY
Rv2488c|M.tuberculosis_H37Rv RTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGH
TH_3225|M.thermoresistible__bu R--------------------GRRALAAAQAKRDAADSAAAHDLLAIAER
Mvan_5002|M.vanbaalenii_PYR-1 R--------------------GARALAAAQAKRDAAAPAEAQELLSTAEL
MSMEG_0321|M.smegmatis_MC2_155 R--------------------GARAVAAAQAKRDAADLQAAYELLAIAEL
MAB_3361|M.abscessus_ATCC_1997 R--------------------GRRALAAAQSKYDAAAFDAARELLGVADM
MMAR_0085|M.marinum_M R--------------------ASRALDAAMTSLEAGMPDSATRLVASAAA
Mflv_1156|M.gilvum_PYR-GCK R-----------------------RIRAAEHHVVAGDMRRAATLLEQALV
MUL_2555|M.ulcerans_Agy99 R--------------------EQLLASAAFVALQAAQLDEAERLLADAGL
MAV_2364|M.avium_104 R-----------------GGGLAAALVLAEAVSWQGRGEEADSILLGADV
MLBr_02341|M.leprae_Br4923 T-------------------------LAAMLDRSIGGRGSVVGLVGPAGI
* :
Mb0393|M.bovis_AF2122/97 SHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRVWMTRGRIQEG
Rv2488c|M.tuberculosis_H37Rv ERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEG
TH_3225|M.thermoresistible__bu APLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQD-
Mvan_5002|M.vanbaalenii_PYR-1 GRLSELQQAQAARLRAQMEFTRRRGGDTGARPLDETASQLLTAAASFEQ-
MSMEG_0321|M.smegmatis_MC2_155 SPLSDLQRAQIARLRAQMEFSHSRREDSGPAQLRDAAAMLLDAARRLES-
MAB_3361|M.abscessus_ATCC_1997 TPLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEAARCLEN-
MMAR_0085|M.marinum_M AADDELIAARCELIRAKIAFAASRGSD--------APPLLLAAAQRMQR-
Mflv_1156|M.gilvum_PYR-GCK DLRPGVLCAIALNLLAGVRMVEDDYIR--------AVELLERARADADN-
MUL_2555|M.ulcerans_Agy99 GGGASASALLISSFISLYRYG-------------DVTATHRRLVERLQS-
MAV_2364|M.avium_104 DDADEWLIARWGCLRAANLAWGCGDAEG-------ATRVLAEVKQRLAT-
MLBr_02341|M.leprae_Br4923 GKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISG-
Mb0393|M.bovis_AF2122/97 RAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAAGMEQAQQAL
Rv2488c|M.tuberculosis_H37Rv LAWFAAALADHDAHPAGADPGLYARALADRALIDAVAGITDRLDDAQKAL
TH_3225|M.thermoresistible__bu ----VDAPAARESYLEAFAALMYAGRLA---PSGALLEAADAVQAAFARA
Mvan_5002|M.vanbaalenii_PYR-1 ----LDGYVSREAYLEALAAAMFAGRLG---DPGAVPRIAAAASAALDRL
MSMEG_0321|M.smegmatis_MC2_155 ----LDDELALQTHLEAIAAAMYAGHLG---APDALLTTAAAAQAAVDRL
MAB_3361|M.abscessus_ATCC_1997 ----LDDNLARETYLDAVGAAMYGGRLC---PRGGAVEVAEPARLAPAGA
MMAR_0085|M.marinum_M ----LDPSESRKAYLGAVLASILVGRMAT-DQHNSSPSVAKAASNAPA-A
Mflv_1156|M.gilvum_PYR-GCK -----DAVLVTTLLSLGFCLGMTG-------SFTAQLATVREAVAVAERA
MUL_2555|M.ulcerans_Agy99 -----ADDLDGETLTRMVNLLLAVS------MFAADPALWQITDGLVDSL
MAV_2364|M.avium_104 ------EGSLQLIDALDVSIGFFRGDIAR----TIELGPRLCEPDVVPMA
MLBr_02341|M.leprae_Br4923 --------LDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELPRLD
.
Mb0393|M.bovis_AF2122/97 VIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRW
Rv2488c|M.tuberculosis_H37Rv AIARDIEDPALLARALTACG--GVAAYNADLARPWLAEAVGLARAVGDKW
TH_3225|M.thermoresistible__bu PEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEVVHW
Mvan_5002|M.vanbaalenii_PYR-1 PESARPVDALLRGIVARITGGVSAGAAPLRLAMDLMQEQARNNDHRVARW
MSMEG_0321|M.smegmatis_MC2_155 ASRDDPIALLLDGVAKCLTGDVGDAAVPLRKALTAWCSAAQHGDGAVLPW
MAB_3361|M.abscessus_ATCC_1997 QP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEADR--PANTSW
MMAR_0085|M.marinum_M PHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERDIG------V
Mflv_1156|M.gilvum_PYR-GCK GVPALTSRALAMWVHVSFQAGNGLDSAALLRAVDLEDPEDNTP-------
MUL_2555|M.ulcerans_Agy99 ADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDRLAE------------
MAV_2364|M.avium_104 TVWAAVATCGALTAVGRFSEVGRIAAAGVRATAQCRAG------------
MLBr_02341|M.leprae_Br4923 PDARRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDS-----------
Mb0393|M.bovis_AF2122/97 RLAQILTFQA-VDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCL
Rv2488c|M.tuberculosis_H37Rv RLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWAL
TH_3225|M.thermoresistible__bu LVPAFPVLQESAGHELWDENLVDALSEAVVRQAR-DAGALAGLPQALVYR
Mvan_5002|M.vanbaalenii_PYR-1 MVPAFPIMQETAALELWDETVVHHLASVVVRRAR-DAGALEALPQVLAYR
MSMEG_0321|M.smegmatis_MC2_155 IFVGYPIVQESAVDELWDDTLMERLADAMVRYTR-DAGALAILPAALSCR
MAB_3361|M.abscessus_ATCC_1997 MEQAFPIALESATHEVWDDDMWHHLATRAVHIAR-EVGALSLLPAALIYR
MMAR_0085|M.marinum_M AEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLR-AAGALTMLPVALVTF
Mflv_1156|M.gilvum_PYR-GCK -IPFRASAARGLSLALTGRLAEADGQLAAVAQRSAQRGAEQDVMAVLGYR
MUL_2555|M.ulcerans_Agy99 -LEPWDVMRVALAGYYVDLIDDFRSVLVPLADREIEGGAATIALATLALV
MAV_2364|M.avium_104 --AQRFAIGLAEVMAATAAGDYPAAERIHKRYAALATGLPAAEAMVDAML
MLBr_02341|M.leprae_Br4923 -----MLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIAVAPLSDV
*
Mb0393|M.bovis_AF2122/97 GYAQLMRGELAAAAAQFGEVVDEAEASQEVL---HKANSLQGLAFALAYQ
Rv2488c|M.tuberculosis_H37Rv AAANLWQGNLEAAVGLSREVIGESDAAHDMV---SSCAGQACLAHALAHR
TH_3225|M.thermoresistible__bu AGVHLLFGEFGLADTLLTEAESITAATDHRG---PVRYHRLIIAAWRGDA
Mvan_5002|M.vanbaalenii_PYR-1 AGAHLLAGELSSAATLLEEAASITAATNNYT---PVRYQTLTLAAWRGEP
MSMEG_0321|M.smegmatis_MC2_155 AGAHLLSGEFGTAGNLLDEANAIAVAIADQ----PLRYHRLHLAAWRGST
MAB_3361|M.abscessus_ATCC_1997 AGMHVHAGELDAAAELVQEADAISAATGHA----PIRYHSLILAAWRGSE
MMAR_0085|M.marinum_M AGVCVSAGNFGQADALLDESAAIIAATGAP----PRPAIKTYLAAYRGQE
Mflv_1156|M.gilvum_PYR-GCK TLVAIWRGRYAEADAYAADTMERAEQLGGSM---VIAFSICAAVAAYRGR
MUL_2555|M.ulcerans_Agy99 AAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRGYLGVISACRGDV
MAV_2364|M.avium_104 GVLQLTRGELQEACATLDRSISQLSQGFPLP-WQLVVGALQAQAEGARGD
MLBr_02341|M.leprae_Br4923 ETSTLVAELLGLDQSVTQIGELITERAAGNP---------FFAQEITREL
:
Mb0393|M.bovis_AF2122/97 GELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEA
Rv2488c|M.tuberculosis_H37Rv GDTEAAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARES
TH_3225|M.thermoresistible__bu VEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNGIGRYREALAAARTT
Mvan_5002|M.vanbaalenii_PYR-1 ADAEAVIEAAIADANARGEGRVLGAADYAFAVLYNGLGRYQEACSAARRA
MSMEG_0321|M.smegmatis_MC2_155 AETIAMIDSATAMAHRNGEGRLLAVLGYFAALLYNGAGRYEEAYAAIRPA
MAB_3361|M.abscessus_ATCC_1997 PTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRA
MMAR_0085|M.marinum_M QICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASG
Mflv_1156|M.gilvum_PYR-GCK -EDQARDQAAGALAQGGDYVALTVWASATLAFLEVSRGNYEQALEAAEPL
MUL_2555|M.ulcerans_Agy99 VRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAI
MAV_2364|M.avium_104 SAAAAVALRRVEEAYGPHVAVFLPELELARAWERAAAGDTAGAQTQAMQA
MLBr_02341|M.leprae_Br4923 AERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAA
:
Mb0393|M.bovis_AF2122/97 AWRN-----LSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMT
Rv2488c|M.tuberculosis_H37Rv ATR------FFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITR
TH_3225|M.thermoresistible__bu CEYE-----DLGFYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGT
Mvan_5002|M.vanbaalenii_PYR-1 CEYE-----DLGVHSWVLAELVEAADHCGDTALAVSALERLQERTADTGT
MSMEG_0321|M.smegmatis_MC2_155 CSTK-----NLGFGGWSLVELIEAAVHTGRREAAEEAADRLAAQAGASGT
MAB_3361|M.abscessus_ATCC_1997 CEHE-----DLGLYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQS
MMAR_0085|M.marinum_M ARYD-----DVGMCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGT
Mflv_1156|M.gilvum_PYR-GCK VDLYRDFPGTELMSACFMPDAIESLIAVGRLDEAEPLIAAFERNGAELDR
MUL_2555|M.ulcerans_Agy99 TAPG-EFPPLALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAP
MAV_2364|M.avium_104 AQTA---------RKAGMHLVEMRARHAALRFGDRAQAARVDELASILNS
MLBr_02341|M.leprae_Br4923 AVIG-------FRFGSDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAF
Mb0393|M.bovis_AF2122/97 GHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLEC
Rv2488c|M.tuberculosis_H37Rv GVHRARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILEC
TH_3225|M.thermoresistible__bu PWGLGALAGARALLADG----DEADRLFREALDHLSRSRVVVHRARVHLT
Mvan_5002|M.vanbaalenii_PYR-1 DWGLGTLAGAQALVADD----DHAEALFEESIDRLARTRVAVHLARAHLR
MSMEG_0321|M.smegmatis_MC2_155 DWGLGALAGARAMLADH----DTADALFTEAIERLQRTRIAVELARTHLR
MAB_3361|M.abscessus_ATCC_1997 DWSQGMVARSRALITVG----HDAEPHYREAIQRLTNTRISAHLARAHLI
MMAR_0085|M.marinum_M PTALGIGASATALVSDG----SIADAAYREAITHLRRSPVAVHLARTHLT
Mflv_1156|M.gilvum_PYR-GCK PWQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHARLPMPFERARSALT
MUL_2555|M.ulcerans_Agy99 PRLAIATGAAEALCASD----ERAPALFEKVLGHPAVASFPFEHARIRLA
MAV_2364|M.avium_104 PSAQAVAGHARGLAQHDG-------DLLDAAAHRFADLGALAFAADAAAQ
MLBr_02341|M.leprae_Br4923 RHPLIRTVAYESQLKSD-------RARLHRRLAAAIEARAPHSVDQHAVL
Mb0393|M.bovis_AF2122/97 LAGLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDA
Rv2488c|M.tuberculosis_H37Rv LASVMADAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKS
TH_3225|M.thermoresistible__bu YGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAE---------------
Mvan_5002|M.vanbaalenii_PYR-1 YGEWLRRALRRNDAREQLTLASGMFTRFGAAAFAE---------------
MSMEG_0321|M.smegmatis_MC2_155 YGEWLRRVNRRPDARRHLGVAFDMFTRMGAAGFAE---------------
MAB_3361|M.abscessus_ATCC_1997 YGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAE---------------
MMAR_0085|M.marinum_M YGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAE---------------
Mflv_1156|M.gilvum_PYR-GCK LGEVLRRLRRR-DAAAAVRDALAQFEELGVPLWVA---------------
MUL_2555|M.ulcerans_Agy99 YGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQ---------------
MAV_2364|M.avium_104 AASEHARRGDRRKEVESSTWAHALAGQCGSR-------------------
MLBr_02341|M.leprae_Br4923 IAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVS--------------
. * .
Mb0393|M.bovis_AF2122/97 MGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVV
Rv2488c|M.tuberculosis_H37Rv MGDSEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVA
TH_3225|M.thermoresistible__bu ------------------RSRRELIAVGEKVRRQPLTSGDELTAQEAQIA
Mvan_5002|M.vanbaalenii_PYR-1 ------------------RTRRELIATGEKARRQPVTSGAQLTAQESQIA
MSMEG_0321|M.smegmatis_MC2_155 ------------------RARRELTATGEKVRKQPVSSGDELTAQEAQIA
MAB_3361|M.abscessus_ATCC_1997 ------------------RAERELRATGAKVRKRSASSEKALTAQEAQIA
MMAR_0085|M.marinum_M ------------------RARRELSATGEAVYVQPTGITVDLTTQESHIA
Mflv_1156|M.gilvum_PYR-GCK ------------------RARIALSG----LAVSGSAVGSELTDSERRIA
MUL_2555|M.ulcerans_Agy99 ------------------RARNELRAAGTAVRHSAAVGPAPLTAQERLVA
MAV_2364|M.avium_104 -----------------------------TPALDAAARPLPFSGRERQIV
MLBr_02341|M.leprae_Br4923 --------------------WEHATKIADALTAEDPHRAAMCIAPRTRLC
. :
Mb0393|M.bovis_AF2122/97 RLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT
Rv2488c|M.tuberculosis_H37Rv LLVGEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRG
TH_3225|M.thermoresistible__bu GLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTA
Mvan_5002|M.vanbaalenii_PYR-1 RLAGDGLTNQEIGAQLFISTHTVDWHLRKVFVKLGITSRRQLRSASWAS-
MSMEG_0321|M.smegmatis_MC2_155 RLAADGLTNQEIGSQLFISTHTVEWHLRKVFVKLGIGSRRQLRTIEWAG-
MAB_3361|M.abscessus_ATCC_1997 RMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR----
MMAR_0085|M.marinum_M RLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRELRAILMESP
Mflv_1156|M.gilvum_PYR-GCK ELAASGMSNRDVAETLFVSVKTIETNLSRVYRKLGIRSRAQLGRMLR---
MUL_2555|M.ulcerans_Agy99 ELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAGLHDALDAIH
MAV_2364|M.avium_104 NLVAAGLSNREIADRLVISVRTVEGHLYRLFTKLGINNRDQLIQLIRRDA
MLBr_02341|M.leprae_Br4923 GIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDRLH--
:. * * . . . . . : :
Mb0393|M.bovis_AF2122/97 ---------
Rv2488c|M.tuberculosis_H37Rv ESERGPSRP
TH_3225|M.thermoresistible__bu TW-------
Mvan_5002|M.vanbaalenii_PYR-1 ---------
MSMEG_0321|M.smegmatis_MC2_155 ---------
MAB_3361|M.abscessus_ATCC_1997 ---------
MMAR_0085|M.marinum_M ---------
Mflv_1156|M.gilvum_PYR-GCK ---------
MUL_2555|M.ulcerans_Agy99 AAPDQI---
MAV_2364|M.avium_104 S--------
MLBr_02341|M.leprae_Br4923 ---------