For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MRAALPAAMMNAMSDASPQAADDPQVAGFLCTATSAPTGLIIEGDAGIGKTTLWLSLLQTARMRGFQVLT ARVGQAESVMAFAALADLLGAVSDEHFAALPPLQRLALDRVLLRAGADGPATDQRVVAAGFVSLLHILAA DAPVLIAIDDVQWLDASSRTAIEFAVRRLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPPMDA GRLHALISHRLGRTLTRPVVLRIAEMSGGNPFYALELAHTHVNSGDSPPAAEPPLPATLADVVRRRVGLL DDATRTLLLGVACVADPTVELLARAHGASTDEITAGLERAEAAGIVVLEGNRVRFTHPLLAGGVYTDAGP TARRAMHRAIASVESHPELRARHLALAASSGDDEIFAALDQAADSARARGAPAAAAELMDLALGLGAHDP MRRLKAAENHFLAGDTAKAAAALGEVGSIEPPILRAMATSLLATVRMYDNEHRQAVDLLRSALDDAADNV PVQVQVLLRLSFALNSIGELDDARRYARDAVKLAEELGFPGATSAALAWAVHVDFQCGRGLDETALARAM KLYDSTFDVPIIFRAPFVHALAMSWTGRLEQAHQELTAVRGVCLERGAESDMMAIAGFLAINHLWRGQIT DAEAEAAEAVERAEQLGGDDVLIIPMTVRGAIAAYAGRVDDARADARWVLAAVRNRKASHIADWPGMTLC FLEESLGNHREALAALDDSFIAAGPPTTELMYAWHLPDAIEAMVGVGRLDDAEILTAALERNGVEHDRRW MRAVGARCRAMLLAAHGDVAAAEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLRQKATAAKNLTDAL HTFEQLGTPLWAQRARSELARAVVAPAEGLTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTRIYR KLGISSRAELGRRMDQPGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4504 | - | - | 100% (929) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_1156 | - | 0.0 | 48.04% (893) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_4474 | - | 0.0 | 43.50% (938) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1393 | - | 4e-14 | 25.54% (603) | transcriptional regulatory protein |
| M. tuberculosis H37Rv | Rv1358 | - | 4e-14 | 25.54% (603) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02341 | - | 4e-11 | 25.23% (444) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 3e-56 | 28.31% (929) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 4e-46 | 26.66% (949) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 1e-21 | 23.60% (949) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_6828 | - | 1e-64 | 28.86% (946) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3931 | - | 1e-108 | 42.88% (576) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 8e-21 | 27.21% (555) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_1863 | - | 0.0 | 77.50% (920) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1393|M.bovis_AF2122/97 ------MFLSAPAFRVEPTRSRHSALRWARHRRFADVPRWQMLRSLQIAD
Rv1358|M.tuberculosis_H37Rv ------MFLSAPAFRVEPTRSRHSALRWARHRRFADGPRWQMLRSLQIAD
Mflv_4504|M.gilvum_PYR-GCK MRAALPAAMMNAMSDASPQAADDPQVAGFLCTATSAPTGLIIEGDAGIGK
Mvan_1863|M.vanbaalenii_PYR-1 ------------MSGASERSIDDPHVAGFLATARSQPAGLVIEGEAGIGK
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ----------------------------------------MLRGQAGVGK
MMAR_0085|M.marinum_M ---------MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDAGIGK
MSMEG_6828|M.smegmatis_MC2_155 ---------------MVGRSEELAAVTDVLADISTGGAALVIDGDPGIGK
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ----------MIGGELLIGRDSELAAIRRALNGADHHRGVVIAGAAGVGK
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb1393|M.bovis_AF2122/97 QIARTGHMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGST
Rv1358|M.tuberculosis_H37Rv QIARTGHMPVRRLDLIWISARNAARRELDLGVAALVEAVTLLTADVEGST
Mflv_4504|M.gilvum_PYR-GCK TTLWLSLLQTARMRGFQVLTARVGQAESVMAFAALADLLGAVSDEHFAAL
Mvan_1863|M.vanbaalenii_PYR-1 TTLWLTVRQRAGDLGFRVLTARAGQAESVMAFAALADLLDDVGDEVFAQL
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 TALLRYVLGKAS--GQLIAQASGIQSEMELAFAGLQQFCAPL-TKYSGAI
MMAR_0085|M.marinum_M TTLLTDLVDNAP--DLRVLRVRGAEMEMELTYSGVQQLCGPL-MSLIGQL
MSMEG_6828|M.smegmatis_MC2_155 STLLAAASDWAVANGYARLGCSGLQSQMEIGYAGLHELLHPLLAQVD-AL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 TWLARAALRRAGASGEQIKWIVGTQSAQALPLGAFIGLLGDAMSEPLTSV
MLBr_02341|M.leprae_Br4923 ---------------MTTALVCVACGAELRSIAKFCDECGSP--------
Mb1393|M.bovis_AF2122/97 RLSQTRLNELAADYPTLDQNISEAVAAHGGVTRPVDQEVGSGLVVAFLRA
Rv1358|M.tuberculosis_H37Rv RLSQTRLNELAADYPTLDQNISEAVAAHGGVTRPVDQEVGSGLVVAFLRA
Mflv_4504|M.gilvum_PYR-GCK PPLQRLALDRVLLRAGADGPATDQRVVAAGFVSLLHILAADAPVLIAIDD
Mvan_1863|M.vanbaalenii_PYR-1 PGLQRLALDRVLLRAGGDGPPTDQRVVAAAFVSVLQALAGESPVLIAIDD
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 PDPQREALTIAFGTR--SGPPPDRFLIGLAVLSLLAAAAEHQPVLCVIDD
MMAR_0085|M.marinum_M PEPQLDALEIALGRK--RGRAPDRLLLGLAVLTLVGEASRASPILCVVDD
MSMEG_6828|M.smegmatis_MC2_155 PPRQRAALMTAFGLE--DGPPPDRMLIGLSVLGLLEEAAGNRRLFLVIDD
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 RR----------------------------VIETFVARQRRGRVVVGVDD
MLBr_02341|M.leprae_Br4923 ------------------------------VVEAETPAEYKQVTVLFADV
Mb1393|M.bovis_AF2122/97 GDAIACALELQLSTLAP-MRPRVGVHTGDVRLRGDGTITGSAINESACLR
Rv1358|M.tuberculosis_H37Rv GDAIACALELQLSTLAP-MRPRVGVHTGDVRLRGDGTITGSAINESACLR
Mflv_4504|M.gilvum_PYR-GCK VQWLDASSRTAIEFAVRRLKGAFGVVVTERCVPGDGTTAG--WLTLERPD
Mvan_1863|M.vanbaalenii_PYR-1 AQWLDSSSRAAIEFAVRRLRGPFGVLVTERCAPGEGATAG--WLKLDRPD
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRDGTDSELAG--LPELTVHG
MMAR_0085|M.marinum_M AQWVDSASVQALAFVARRIHVDPVAMVFATRDRGPDALTG--HCELSLQG
MSMEG_6828|M.smegmatis_MC2_155 AQWLDPSSVDVLNFVARRLSNAPLMMLCSTRTTLDGFSVQFDGLPRLTMG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 AHLLDGLSALVVHQLAQSGGVRLVVTVRTGSHQPDAVTALWKDDLLTRLD
MLBr_02341|M.leprae_Br4923 VGSMDIAAAVGLERLREIMTELVSRAAGVIERYG----------------
Mb1393|M.bovis_AF2122/97 DLAHEGQTLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCH
Rv1358|M.tuberculosis_H37Rv DLAHEGQTLLSAATGDLVIDQLPANTWLTDVGKYPLRGLHRQERVIQLCH
Mflv_4504|M.gilvum_PYR-GCK GLIRVSVPPMDAGRLHALISHRLG-------------RTLTRPVVLRIAE
Mvan_1863|M.vanbaalenii_PYR-1 ALERVYVRPMTTGQLHSLISERLG-------------RTLARPSILRIAE
TH_3931|M.thermoresistible__bu -----------------VLLARLG-------------RTFPRAVMVQIHH
MAB_3361|M.abscessus_ATCC_1997 ---------LRAADAGTLLDSVIP-------------GLLDERVRDRIVA
MMAR_0085|M.marinum_M ---------LEDHDARLVLSTAIP-------------GRLNDSVAETVLA
MSMEG_6828|M.smegmatis_MC2_155 --------PLEPADAAELLALTLRDP--------ERSDRVDEVARQRILE
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ------LEPLSAAATREVIESTLG-------------GPVDARCAARFRR
MLBr_02341|M.leprae_Br4923 -------------------------------------GTVDKFTGDGIMA
Mb1393|M.bovis_AF2122/97 RDLRNEFPPLRMSVGNRSS----LPAQFTTFVGRDAQINEVQEVLTNYRL
Rv1358|M.tuberculosis_H37Rv RDLRNEFPPLRMSVGNRSS----LPAQFTTFVGRDAQINEVQEVLTNYRL
Mflv_4504|M.gilvum_PYR-GCK MSGGNPFYALELAHTHVNS----GDSP---PAAEPPLPATLADVVRRR--
Mvan_1863|M.vanbaalenii_PYR-1 ISGGNPFFALELALALSDG----QGS------GEPPLPATLADVVRHR--
TH_3931|M.thermoresistible__bu ISGGNPFYALELARAMDDG----SPL--------VRLPSSLTELVRAR--
MAB_3361|M.abscessus_ATCC_1997 ETQGNPLALLELPRDMTAE----ELAGGFGWPDGGRLAGQIEQTFLRR--
MMAR_0085|M.marinum_M EANGNPLALLELHNALIRG----ELAGGYGLANATRTETQIERTFVSR--
MSMEG_6828|M.smegmatis_MC2_155 QANGNPMAVIELTIALIES----GDGAPIFAGEPLPTTRRVERAFLTQ--
MUL_2555|M.ulcerans_Agy99 -------------------------------------MPALSANLVAS--
MAV_0578|M.avium_104 LTGGNTLFLRQLLSDQMAAGRMRRVAGVWMWDGDVAVSASLSDTVGRQ--
MLBr_02341|M.leprae_Br4923 IFGAPTALEDHALRACLAA------------LGVQEKARRLAAEVGDR--
: .
Mb1393|M.bovis_AF2122/97 VTLRGEGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHAL
Rv1358|M.tuberculosis_H37Rv VTLRGEGGVGKTRLAIQIAAASEFRDGLCFVDLAPIADPGMVSTTAAHAL
Mflv_4504|M.gilvum_PYR-GCK ---VGLLDDATRTLLLGVACVADPTVELLARAHGASTDEITAGLERAEAA
Mvan_1863|M.vanbaalenii_PYR-1 ---IGRLDEQTRSVLLSIACVADATVELLARAHDVTAEEVTERLERVEST
TH_3931|M.thermoresistible__bu ---IGRIGADARNVLLAAACSAAPTVESVARAVGVDEPRVVRLLSDAVDR
MAB_3361|M.abscessus_ATCC_1997 ---VQQLPAHTQTLLLAAATDPLGDVTLLARAAQQLG-IPMHAIAPAEAA
MMAR_0085|M.marinum_M ---LRALPSETKTFLLVAAAESTARPEWLWAAAHRLG-IGPEAAAPAEAA
MSMEG_6828|M.smegmatis_MC2_155 ---LGPLSDESRLLLLLIATG-NGLLSEIDWAADHLGFSLTEHLGSLEES
MUL_2555|M.ulcerans_Agy99 ------IDRHPERITLRCDDLQSVFAELGAGPGDRVAALPGDRTRRRVCG
MAV_0578|M.avium_104 ---LGRLTPPLALVVDTLSQCEPLPVDLLCDLASREDLVAAEAMGLVTVE
MLBr_02341|M.leprae_Br4923 -------DGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMES
.
Mb1393|M.bovis_AF2122/97 GLIDRPGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPE
Rv1358|M.tuberculosis_H37Rv GLIDRPGSSTFDTLSHAIGNCHMLMVLDNCEHVLDACAELVVELLGACPE
Mflv_4504|M.gilvum_PYR-GCK GIVVLEGNRVRFTHPLLAGGVYTDAGPTARRAMHRAIASVES-----HPE
Mvan_1863|M.vanbaalenii_PYR-1 GIITVEGNRVRFTHPLLASGVYTDAGPTARRAMHRTMGALES-----QPE
TH_3931|M.thermoresistible__bu DIIRMDGHRICFSHPLLARGVYDDATATRRRAMHRRLAEIVD-----EPE
MAB_3361|M.abscessus_ATCC_1997 DLVELST-RVRFRHPLVRSAVYISANPLERRRIHGVLAGATDPGA--DPD
MMAR_0085|M.marinum_M GLIAAQG-SVRFRHPLIRAAVYHSSSAAERRRVHAALAASIAGPD--DDD
MSMEG_6828|M.smegmatis_MC2_155 GLITVAGGRIQIRHPLIRSTVYGAAALASRAAVHRALAAAAT-----DPA
MUL_2555|M.ulcerans_Agy99 PACELSGGRFRPSARPQSCPGLTEAASPGR-------------------S
MAV_0578|M.avium_104 RTP--RALMARLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQD-ADM
MLBr_02341|M.leprae_Br4923 VAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPR
Mb1393|M.bovis_AF2122/97 LSILATSRESIGVTGEVTWVVPSLSPANEAIQLFTERARLVQPNFEIVAD
Rv1358|M.tuberculosis_H37Rv LSILATSRESIGVTGEVTWVVPSLSPANEAIQLFTERARLVQPNFEIVAD
Mflv_4504|M.gilvum_PYR-GCK LRARHLALAASSGDDEIFAALDQAADSARARGAPAAAAELMDLALGLGAH
Mvan_1863|M.vanbaalenii_PYR-1 LKARHLALASASGDDEIFTALDQAADSARARGAPAAAAELMDLAIGLGAD
TH_3931|M.thermoresistible__bu LQARHLAIAVGWADPQVLACLDRAAEAARLRGAPSTAAELIDMAIGLGGD
MAB_3361|M.abscessus_ATCC_1997 RRAWHRAHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTAD
MMAR_0085|M.marinum_M HRVWHRAHAAEAPDAQTADDLERSAERARARGGLSAAASFLEHATKLTPD
MSMEG_6828|M.smegmatis_MC2_155 RAAWHRAEAAFGPNEEVAADLERVADRARVRGAGAEAAAALRRAAALTDD
MUL_2555|M.ulcerans_Agy99 RGPLHLAR--------------CAAELTIRRGDACQAIELLRRAGELSDR
MAV_0578|M.avium_104 QATVRRALLTLESDLDPQPELYLESARHAMTLLDLDLADRLANAAARAGA
MLBr_02341|M.leprae_Br4923 QPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTR---
Mb1393|M.bovis_AF2122/97 NFAAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGAR
Rv1358|M.tuberculosis_H37Rv NFDAVSEICRRLDGMPLAIELAAARLRSLSPNEIANSLDDRFRLLTGGAR
Mflv_4504|M.gilvum_PYR-GCK DPMR--------------------RLKAAENHFLAGDTAKAAAALGEVGS
Mvan_1863|M.vanbaalenii_PYR-1 DPLR--------------------RMKSAENHFLAGDTAKAAAALGRIDT
TH_3931|M.thermoresistible__bu SPER--------------------RLMSARNHVDAGDGDSARAILKRSSA
MAB_3361|M.abscessus_ATCC_1997 PAARG-----------------RRALAAAQSKYDAAAFDAARELLGVADM
MMAR_0085|M.marinum_M PFVRA-----------------SRALDAAMTSLEAGMPDSATRLVASAAA
MSMEG_6828|M.smegmatis_MC2_155 PQERLR-----------------RMTVAAEVARSSGLIAESVRILREAEP
MUL_2555|M.ulcerans_Agy99 PRRREQ-----------------LLASAAFVALQAAQLDEAERLLADAGL
MAV_0578|M.avium_104 PGAAG------------------VRAMNLVLLGRGEQAEEALRAITDGAD
MLBr_02341|M.leprae_Br4923 -------------------------LVAEAVQLAKGLEVEVFSVFCESHA
.
Mb1393|M.bovis_AF2122/97 STVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAG
Rv1358|M.tuberculosis_H37Rv STVQRQQTLRASMDWSYALLTDTERILFRRLAVFVGGFDLTAASEVAAAG
Mflv_4504|M.gilvum_PYR-GCK IEPPILRAMATSLLATVRMYDNEHR----------------QAVDLLRSA
Mvan_1863|M.vanbaalenii_PYR-1 IEPPVLRALAASLLATVRMYENEHT----------------EAVELLRGA
TH_3931|M.thermoresistible__bu EMTGAPRAQVLRLLGGLEILYGSYL----------------DAADALRRA
MAB_3361|M.abscessus_ATCC_1997 TPLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENL
MMAR_0085|M.marinum_M AADDELIAARCELIRAKIAFAASRG--------SDAPPLLLAAAQRMQRL
MSMEG_6828|M.smegmatis_MC2_155 LIREHESETPLAITRFVLNATAATPG---------------QSADELLAL
MUL_2555|M.ulcerans_Agy99 GGGASASALLISSFISLYRYG--------------------DVTATHRRL
MAV_0578|M.avium_104 GDASDRHYWATVRAANLVWMLGRPA----------------DAALVLDGL
MLBr_02341|M.leprae_Br4923 TDVAFDVVAQLVRAVAQISGLDDRS----------------ARARVREQI
Mb1393|M.bovis_AF2122/97 GDDFVERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEKLNE
Rv1358|M.tuberculosis_H37Rv GDDFVERYSVLDQLTLLVDKSLVVAEESRGSTRYRLLETVRQYALEKLNE
Mflv_4504|M.gilvum_PYR-GCK LDDAADNVPVQVQVLLRLS--FALNSIGELDD------------------
Mvan_1863|M.vanbaalenii_PYR-1 LDDGAGNVPILVQVLLRLS--FALNSIGDLDD------------------
TH_3931|M.thermoresistible__bu LTDATDDAVLRARILTLLA--FVEFNTGRRAA------------------
MAB_3361|M.abscessus_ATCC_1997 DDNLARETYLDAVGAAMYGGRLCP--RGGAVE------------------
MMAR_0085|M.marinum_M DPSESRKAYLGAVLASILVGRMATDQHNSSPS------------------
MSMEG_6828|M.smegmatis_MC2_155 SRKIADDDPGRRQLLWAAAIECRMHGLPEHSR------------------
MUL_2555|M.ulcerans_Agy99 VERLQSADDLDGETLTRMVNLLLAVSMFAADP------------------
MAV_0578|M.avium_104 AARPETPAQAAARCAVQACLDAVAARCQLAAER-----------------
MLBr_02341|M.leprae_Br4923 PDADTQDLLLLDDLLGIADPAVELPRLDPDAR------------------
Mb1393|M.bovis_AF2122/97 SEEIDGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEIDNLRAAFTW
Rv1358|M.tuberculosis_H37Rv SEEIDGVRARHRTHYATMAAGLNVPASTDYEQRLLQAEAEIDNLRAAFTW
Mflv_4504|M.gilvum_PYR-GCK ------------------------------------ARRYARDAVKLAEE
Mvan_1863|M.vanbaalenii_PYR-1 ------------------------------------AARYVRDAVKLAEE
TH_3931|M.thermoresistible__bu ------------------------------------AAADADEAVECATR
MAB_3361|M.abscessus_ATCC_1997 ------------------------------------VAEPARLAPAGAQP
MMAR_0085|M.marinum_M ------------------------------------VAKAASNAPAAPHP
MSMEG_6828|M.smegmatis_MC2_155 ----------------------------------------RDVVAEIGRL
MUL_2555|M.ulcerans_Agy99 -----------------------------------------ALWQITDGL
MAV_0578|M.avium_104 -------------------------------------ARAALDSESLPDF
MLBr_02341|M.leprae_Br4923 -------------------------------------------RRRLTAL
Mb1393|M.bovis_AF2122/97 SRGNGDIAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLVPAGV
Rv1358|M.tuberculosis_H37Rv SRGNGDIAAALQLASALQPLWSQGRMREGLAWLESILEREGDNHLVPAGV
Mflv_4504|M.gilvum_PYR-GCK LGFPGATSAALAWAVHVDFQCGRGLDETALARAMKLYDSTFDVPIIFRAP
Mvan_1863|M.vanbaalenii_PYR-1 LGVPGIISAALAWSVHVNIQCGRGLDEESLRRAMELYDSTLDVPIIFRAP
TH_3931|M.thermoresistible__bu AGDRGVLSQALAMRTLVTCLLGRGFDPAALHRALELEEPGSGDLGITRTS
MAB_3361|M.abscessus_ATCC_1997 ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEADR-PANTSWMEQA
MMAR_0085|M.marinum_M PRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERDIGVAEPGWHDLT
MSMEG_6828|M.smegmatis_MC2_155 DDDPHDPLTAIALALADDTGKGAG-LRARLPQLVDTVGDSPLLMLSLAFA
MUL_2555|M.ulcerans_Agy99 VDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDRLAELEPWDVMR
MAV_0578|M.avium_104 HAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEASHMRFWFGAVY
MLBr_02341|M.leprae_Br4923 INVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRP
Mb1393|M.bovis_AF2122/97 WARALAEKVILKAWPATSPMGAPDIVAQAHHALALARDAGDCAVLARALV
Rv1358|M.tuberculosis_H37Rv WARALAEKVILKAWPATSPMGAPDIVAQAHHALALARDAGDCAVLARALV
Mflv_4504|M.gilvum_PYR-GCK FVHALAM-------SWTGRLEQAHQELTAVRGVCLERGAESDMMAIAGFL
Mvan_1863|M.vanbaalenii_PYR-1 FVHALVM-------SWTGRLEQAHRELTAMRAVCVERGAESDMMAIAGFL
TH_3931|M.thermoresistible__bu GLHAMLL-------AYTGRFDAAVEVMRAVARHCRDRGEGLDLTYIALHR
MAB_3361|M.abscessus_ATCC_1997 FPIALES-------ATHEVWDDDMWHHLATRAVHIAREVG--ALSLLPAA
MMAR_0085|M.marinum_M ARVCLD------------LFDQDAYNFLAARQVEDLRAAG--ALTMLPVA
MSMEG_6828|M.smegmatis_MC2_155 AEAVTDR-------------AGALKCWTHVQNQARNCGSLAEECEGLRGA
MUL_2555|M.ulcerans_Agy99 VALAGYY---------VDLIDDFRSVLVPLADREIEGGAATIALATLALV
MAV_0578|M.avium_104 GRACRLT----------GRIDEFVSTARRLADSAR-DVPGLAYANLALLL
MLBr_02341|M.leprae_Br4923 EYHGALR-----------HVVGAQIIAVAPLSDVETSTLVAELLGLDQSV
Mb1393|M.bovis_AF2122/97 ACGCGSGCDTEAAQPYFAEAIELARAINDEWTLSQIDYWQVVGIFISGQP
Rv1358|M.tuberculosis_H37Rv ACGCGSGCDTEAAQPYFAEAIELARAINDEWTLSQIDYWQVVGIFISGQP
Mflv_4504|M.gilvum_PYR-GCK AINHLWRGQITDAEAEAAEAVERAEQLGGDDVLIIPMTVRGAIAAYAGRV
Mvan_1863|M.vanbaalenii_PYR-1 AINHLWRGQIAEAEAEASEAVERAEQLGGDDVLIIPMTVRGTLAAYAGRV
TH_3931|M.thermoresistible__bu VLVELWRGEVRAAATIAEEAIESAAVLDGDLPRGVVLLLRQALATYAGRV
MAB_3361|M.abscessus_ATCC_1997 LIYRAGMHVHAGELDAAAELVQEADAISAATGHAPIRYHSLILAAWRGSE
MMAR_0085|M.marinum_M LVTFAGVCVSAGNFGQADALLDESAAIIAATGAPPRPAIKTYLAAYRGQE
MSMEG_6828|M.smegmatis_MC2_155 ANILLTEGHVEAAAMSAQTALHMAESMNIAMTAGSAAAILARALVWQGQG
MUL_2555|M.ulcerans_Agy99 AAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRGYLGVISACRGDV
MAV_0578|M.avium_104 GNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASYFALAEAHGRLGH
MLBr_02341|M.leprae_Br4923 TQIGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVP
:
Mb1393|M.bovis_AF2122/97 IPLRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANGALALSRDV
Rv1358|M.tuberculosis_H37Rv IPLRAAAEQARELADSIGNRFVSRQCRLFACLAQIWEGDANGALALSRDV
Mflv_4504|M.gilvum_PYR-GCK DDARADARWVLAAVRNRKASHIADWPGMTLCFLEESLGNHREALAALDDS
Mvan_1863|M.vanbaalenii_PYR-1 EDARADARWVLDAVKNRQTSHIADWPGMTLCFLEESLRNHREALQALDAK
TH_3931|M.thermoresistible__bu DDARGDGARAAAIFARSGSAILTTLTTSLTGFLELSVGDHVAAIATLRPL
MAB_3361|M.abscessus_ATCC_1997 PTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRA
MMAR_0085|M.marinum_M QICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASG
MSMEG_6828|M.smegmatis_MC2_155 ERARHVLDRARHHLSPAPTILWNDDVHWAAGLAALCEADHTQALGHLTQM
MUL_2555|M.ulcerans_Agy99 VRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAI
MAV_0578|M.avium_104 PAQANEAIAGARSCVPPDFLFMHTGLALATGWALAAGGQLREAVATAQAA
MLBr_02341|M.leprae_Br4923 ATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSVDELI
Mb1393|M.bovis_AF2122/97 TAEAEVANDVVTKVLGLYVEAMALSYIGDSAARTIAGAALEAATELGGIY
Rv1358|M.tuberculosis_H37Rv TAEAEVANDVVTKVLGLYVEAMALSYIGDSAARTIAGAALEAATELGGIY
Mflv_4504|M.gilvum_PYR-GCK F-IAAG---------PPTTELMYAWHLPDAIEAMVGVGRLDDAEILTAAL
Mvan_1863|M.vanbaalenii_PYR-1 F-LDPKQ--------MRSTELMYAWHLPDVIEAMVGVGRLDEAESLTGAL
TH_3931|M.thermoresistible__bu LPILGPD--------LEGTEIITAGFLPDLVEAQVLMGLLDDAEPLVQAL
MAB_3361|M.abscessus_ATCC_1997 C--------------EHEDLGLYSWCLIELIEAAVRCGEHDTAVKAFGQL
MMAR_0085|M.marinum_M A--------------RYDDVGMCGYLLGELIEAAVRCKEHNAATEALGRL
MSMEG_6828|M.smegmatis_MC2_155 T----------------LHRTSRRWAIADLAEAAAGAEKADIARPLLAEA
MUL_2555|M.ulcerans_Agy99 TAPGEFP----------PLALHATRTLFDLVEAAVHTDRLNEARRHVRAA
MAV_0578|M.avium_104 A----------------RLARDRGQPTHELACIQAAAQWGDAAGAVRARA
MLBr_02341|M.leprae_Br4923 D-----------------ANLVDQVRFTAPVEYAFRHPLIRTVAYESQLK
.
Mb1393|M.bovis_AF2122/97 QDLGYGAITRAALAAGDVAAIEASEASWDLRNQHNVVTAHHELMAQAALV
Rv1358|M.tuberculosis_H37Rv QDLGYGAITRAALAAGDVAAIEASEASWDLRNQHNVVTAHHELMAQAALV
Mflv_4504|M.gilvum_PYR-GCK ERNGV---------------------------------------------
Mvan_1863|M.vanbaalenii_PYR-1 EQNGI---------------------------------------------
TH_3931|M.thermoresistible__bu TRNGR---------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 EERAL---------------------------------------------
MMAR_0085|M.marinum_M LKRTK---------------------------------------------
MSMEG_6828|M.smegmatis_MC2_155 EEQAER--------------------------------------------
MUL_2555|M.ulcerans_Agy99 KRLQF---------------------------------------------
MAV_0578|M.avium_104 LADALS--------------------------------------------
MLBr_02341|M.leprae_Br4923 SDRAR---------------------------------------------
Mb1393|M.bovis_AF2122/97 RGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELGKARDDAHAA
Rv1358|M.tuberculosis_H37Rv RGDVTTARRFADEAVLASTGWHLMMALIARARVAIAQDELGKARDDAHAA
Mflv_4504|M.gilvum_PYR-GCK ---------------EHDRRWMRAVGARCRAMLLAAHGDVAAAEQMAHRA
Mvan_1863|M.vanbaalenii_PYR-1 ---------------EHDRHWMKAVGMRCRAMLLAARGDVIAAEQTAHRA
TH_3931|M.thermoresistible__bu ---------------RLDRPWMLAVAARCRAMMLAARGDLAGAVAAVX--
MAB_3361|M.abscessus_ATCC_1997 ---------------AAQSDWSQGMVARSRALITVGH----DAEPHYREA
MMAR_0085|M.marinum_M ---------------ASGTPTALGIGASATALVSDGS----IADAAYREA
MSMEG_6828|M.smegmatis_MC2_155 ------------------LGIDSFLVHRAHALLADSVAE---SEDRFRAA
MUL_2555|M.ulcerans_Agy99 ----------------ADAPPRLAIATGAAEALCASDER---APALFEKV
MAV_0578|M.avium_104 ------------------LPLADAIACHAEALRAGNGEALLTVAAAYRAI
MLBr_02341|M.leprae_Br4923 ------------------LHRRLAAAIEARAPHSVDQHAVLIAEHLEAAG
.
Mb1393|M.bovis_AF2122/97 VACGVGVQTYLAMPDALELLAGLAGEAGNHGQAVRLFGAAAAQRQRTGEV
Rv1358|M.tuberculosis_H37Rv VACGVGVQTYLAMPDALELLAGLAGEAGNHGQAVRLFGAAAAQRQRTGEV
Mflv_4504|M.gilvum_PYR-GCK ISEHDHLP---------------------------MPFERARTRLLLGQL
Mvan_1863|M.vanbaalenii_PYR-1 MAEHDRLP---------------------------MPFERARTQLLLGQL
TH_3931|M.thermoresistible__bu -XXGRRRS---------------------------GPGAAARHR---GAV
MAB_3361|M.abscessus_ATCC_1997 IQRLTNTR---------------------------ISAHLARAHLIYGEW
MMAR_0085|M.marinum_M ITHLRRSP---------------------------VAVHLARTHLTYGEW
MSMEG_6828|M.smegmatis_MC2_155 LGAAERTG---------------------------AELESARTHLLYGVW
MUL_2555|M.ulcerans_Agy99 LGHPAVAS---------------------------FPFEHARIRLAYGMR
MAV_0578|M.avium_104 GDAAAAAD----------------------------AAAQASAAFVEGQQ
MLBr_02341|M.leprae_Br4923 DLHAAYG------------------------------WHMRAAAWATNQD
.
Mb1393|M.bovis_AF2122/97 RHKIWDAGYEAATAALRDAMGDEDFTAAWAEGAAAPLDEAIAYAQRGRGE
Rv1358|M.tuberculosis_H37Rv RHKIWDAGYEAATAALRDAMGDEDFTAAWAEGAAAPLDEAIAYAQRGRGE
Mflv_4504|M.gilvum_PYR-GCK QRRLRQKATAAKNLTDALHTFEQLGTPLWAQRARSELARAVVAPAEG---
Mvan_1863|M.vanbaalenii_PYR-1 QRRLRQKNTAATNLNEALRTFEEMGTPLWVRRARAELARAVVAPAEGLS-
TH_3931|M.thermoresistible__bu RRRRRPDRRGAR-----------AGRPAGGTQPVGLLVRTVPR-------
MAB_3361|M.abscessus_ATCC_1997 LRRCNRRSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRKRSAS
MMAR_0085|M.marinum_M LRRERRRSEARSQLRIAYDMFAQMGAAGFAERARRELSATGEAVYVQPTG
MSMEG_6828|M.smegmatis_MC2_155 LRRRRRIVDARVHLSAALTAFDRAGAVPFAERAAAELRAAGVTSAPRPGT
MUL_2555|M.ulcerans_Agy99 LRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRARNELRAAGTAVRHSAAV
MAV_0578|M.avium_104 HQRGRYAAALAGELAEECG-----GLCTPALRTPAGLKLSG---------
MLBr_02341|M.leprae_Br4923 VRAARVSWEHATKIADALTAEDPHRAAMCIAPRTRLCGIAWRG-------
: :
Mb1393|M.bovis_AF2122/97 RKRPSNGWDALTPAEHKIVKLVTEGLVTKDIAARLFVSPRTVQTHLTHIY
Rv1358|M.tuberculosis_H37Rv RKRPSNGWDALTPAEHKIVKLVTEGLVTKDIAARLFVSPRTVQTHLTHIY
Mflv_4504|M.gilvum_PYR-GCK ----------LTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTRIY
Mvan_1863|M.vanbaalenii_PYR-1 ---------QLTPSEQRVAEMAASGATNKDIASAMFISAKTVEHNLTKIY
TH_3931|M.thermoresistible__bu -------------RTARHGRIPAPGRXRGDRADRAPGSQR---------G
MAB_3361|M.abscessus_ATCC_1997 SEK------ALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVF
MMAR_0085|M.marinum_M ITV------DLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIF
MSMEG_6828|M.smegmatis_MC2_155 HSGADAG--ALTPQELQIAQMAAAGMTNREIADRIYLSHRTVAAHLYKVF
MUL_2555|M.ulcerans_Agy99 GPAP------LTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLF
MAV_0578|M.avium_104 -------------RQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRAC
MLBr_02341|M.leprae_Br4923 -------------RFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDHVY
: . :
Mb1393|M.bovis_AF2122/97 TKLDVTSRVQLVQEAAQHST-----
Rv1358|M.tuberculosis_H37Rv TKLDVTSRVQLVQEAAQHST-----
Mflv_4504|M.gilvum_PYR-GCK RKLGISSRAELGRRMDQPGL-----
Mvan_1863|M.vanbaalenii_PYR-1 RKLGISSRAELGRRMDRAGEP----
TH_3931|M.thermoresistible__bu GRAGPADRTR-GAVADAAGR-----
MAB_3361|M.abscessus_ATCC_1997 AKRGITSRRQLRSGR----------
MMAR_0085|M.marinum_M AKLGVTSRRELRAILMESP------
MSMEG_6828|M.smegmatis_MC2_155 PKLGITRRNQLHAALGAPTGIA---
MUL_2555|M.ulcerans_Agy99 PKLGVTNRAGLHDALDAIHAAPDQI
MAV_0578|M.avium_104 QRVGAQSRDELATIIRSRPAGRES-
MLBr_02341|M.leprae_Br4923 QDRLH--------------------