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VLRGQAGVGKTALLRYVLGKASGQLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDPQREALTIAFG TRSGPPPDRFLIGLAVLSLLAAAAEHQPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRDGTD SELAGLPELTVHGLRAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEELAGGFGWPD GGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTLLARAAQQLGIPMHAIAPAEAADLVELSTRV RFRHPLVRSAVYISANPLERRRIHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAWELEQSAGRAQAKG GVLAAAAFLQRATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIA FAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRGGAVEVAEPARLAP AGAQPARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEADRPANTSWMEQAFPIALESATHEVWDDD MWHHLATRAVHIAREVGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGHAPIRYHSLILAA WRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACEHEDLGLYSWCLIE LIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVARSRALITVGHDAEPHYREAIQRLTNTRISAHL ARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRKRSASSEKALTAQEA QIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3361 | - | - | 100% (889) | LuxR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3891c | - | 7e-05 | 29.63% (81) | LuxR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1522 | - | 9e-05 | 38.18% (55) | putative two-component system response regulator LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 1e-12 | 27.11% (509) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4504 | - | 3e-56 | 28.31% (929) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0386 | - | 2e-12 | 27.11% (509) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 5e-11 | 24.32% (444) | putative regulatory protein |
| M. marinum M | MMAR_0085 | - | 0.0 | 45.06% (890) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 6e-18 | 25.88% (935) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 0.0 | 54.10% (891) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 55.16% (892) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 1e-26 | 27.17% (611) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 0.0 | 55.78% (891) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
TH_3225|M.thermoresistible__bu ----------------MSSRD-----GDVVLHGRAAEIATLRDVMSTARA
Mvan_5002|M.vanbaalenii_PYR-1 ------------MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRT
MSMEG_0321|M.smegmatis_MC2_155 ----------------METGG-----RGQPLHGRAAECDALRRSIADVQS
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M -------------------------MPTVTLVGRHREQQQLQQLLDAARR
Mflv_4504|M.gilvum_PYR-GCK ----------------MRAALPAAMMNAMSDASPQAADDPQVAGFLCTAT
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ------------------------MIGGELLIGRDSELAAIRRALNGADH
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 GVRPVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGE
Rv0386|M.tuberculosis_H37Rv GVRPVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGE
TH_3225|M.thermoresistible__bu GSSRVLVLHGEAGVGKTALLGQLLGDA--AGMRCVQVAGVESDM-----E
Mvan_5002|M.vanbaalenii_PYR-1 GASRSLVLRGEAGIGKTALLDHVVAQA--EGFRTTYVAGVESDM-----E
MSMEG_0321|M.smegmatis_MC2_155 AQSRVLVLRGEAGVGKTALLDFAAQHA--KGFRITQVAGVESDM-----E
MAB_3361|M.abscessus_ATCC_1997 ------MLRGQAGVGKTALLRYVLGKA--SGQLIAQASGIQSEM-----E
MMAR_0085|M.marinum_M GESGVLVLRGDAGIGKTTLLTDLVDNA--PDLRVLRVRGAEMEM-----E
Mflv_4504|M.gilvum_PYR-GCK SAPTGLIIEGDAGIGKTTLWLSLLQTARMRGFQVLTARVGQAES-----V
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 HRG--VVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQ-----A
MLBr_02341|M.leprae_Br4923 MTTALVCVACGAELRSIAKFCDECGSP---------VVEAETPAEYKQVT
Mb0393|M.bovis_AF2122/97 VALRDEGNYAGPTINR-TARLRDLAHGGQTVLSGVT--ESLVIDRLPDKA
Rv0386|M.tuberculosis_H37Rv VALRDEGNYAGPTINR-TARLRDLAHGGQTVLSGVT--ESLVIDRLPDKA
TH_3225|M.thermoresistible__bu LAYAGLHQLCAPLLDR-LDDLPSPQRDVLNVAFGRG--AGPAPGRFLVGL
Mvan_5002|M.vanbaalenii_PYR-1 LAFAGLHQLCAPLLTH-LDELPDPQRDALTVAFGQG--AGATPDRFLVGL
MSMEG_0321|M.smegmatis_MC2_155 LAYAGLQQLCAPLMNN-LDDLPEPQRDALAVAFGLG--VGQTPDRFLVGL
MAB_3361|M.abscessus_ATCC_1997 LAFAGLQQFCAPLTKY-SGAIPDPQREALTIAFGTR--SGPPPDRFLIGL
MMAR_0085|M.marinum_M LTYSGVQQLCGPLMSL-IGQLPEPQLDALEIALGRK--RGRAPDRLLLGL
Mflv_4504|M.gilvum_PYR-GCK MAFAALADLLGAVSDEHFAALPPLQRLALDRVLLRAGADGPATDQRVVAA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LPLGAFIGLLGDAMSEPLTSVRRVIETFVARQRRGRVVVGVDDAHLLDGL
MLBr_02341|M.leprae_Br4923 VLFADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDG
Mb0393|M.bovis_AF2122/97 WLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLT
Rv0386|M.tuberculosis_H37Rv WLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLT
TH_3225|M.thermoresistible__bu AVLNLLAAAGADQP-----------------LLCVIDDAQWLDRVSLQTL
Mvan_5002|M.vanbaalenii_PYR-1 AVLSLMAAASTGGP-----------------LLCVIDDAQWLDQVSVQTL
MSMEG_0321|M.smegmatis_MC2_155 AVLSLMAAAADEKP-----------------LLCIVDDAQWLDSVSVQTL
MAB_3361|M.abscessus_ATCC_1997 AVLSLLAAAAEHQP-----------------VLCVIDDAQWLDRVSLQTL
MMAR_0085|M.marinum_M AVLTLVGEASRASP-----------------ILCVVDDAQWVDSASVQAL
Mflv_4504|M.gilvum_PYR-GCK GFVSLLHILAADAP-----------------VLIAIDDVQWLDASSRTAI
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 SALVVHQLAQ------------------------------------SGGV
MLBr_02341|M.leprae_Br4923 IMAIFG--------------------------------------------
Mb0393|M.bovis_AF2122/97 RFVGRGAQITEVHRLVTDNRLV----------TLTGAGGVGKTRLAAQLA
Rv0386|M.tuberculosis_H37Rv RFVGRGAQITEVHRLVTDNRLV----------TLTGAGGVGKTRLAAQLA
TH_3225|M.thermoresistible__bu GFVAR-RLMAEPVAMVFALRDD----------IHEALVGVPALAVPGLAD
Mvan_5002|M.vanbaalenii_PYR-1 AFVAR-RLLAEPIAMVFAARDT----------GAEALSGLPELAVPGLSD
MSMEG_0321|M.smegmatis_MC2_155 AFVAR-RLLAEPVGLIFAVRDH----------GAPALAGLPELLVDGLSD
MAB_3361|M.abscessus_ATCC_1997 AFVTR-RLGSEPVAMLFAVRDG----------TDSELAGLPELTVHGLRA
MMAR_0085|M.marinum_M AFVAR-RIHVDPVAMVFATRDR----------GPDALTGHCELSLQGLED
Mflv_4504|M.gilvum_PYR-GCK EFAVR--RLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPPMDA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 RLVVTVRTGSHQPDAVTALWKD---------------DLLTRLDLEPLSA
MLBr_02341|M.leprae_Br4923 -------------------------------------------APTALED
Mb0393|M.bovis_AF2122/97 AQIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFL
Rv0386|M.tuberculosis_H37Rv AQIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFL
TH_3225|M.thermoresistible__bu ADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPR-----------
Mvan_5002|M.vanbaalenii_PYR-1 GEARDLLDSVVVGRLDDRVRDRIIAETRGNPLALLDLPH-----------
MSMEG_0321|M.smegmatis_MC2_155 TDARELLDSVILGRLDERVRDRVVAETRGIPLALLEVPR-----------
MAB_3361|M.abscessus_ATCC_1997 ADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPR-----------
MMAR_0085|M.marinum_M HDARLVLSTAIPGRLNDSVAETVLAEANGNPLALLELHN-----------
Mflv_4504|M.gilvum_PYR-GCK GRLHALISHRLGRTLTRPVVLRIAEMSGGNPFYALELAH-----------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 AATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLS-----------
MLBr_02341|M.leprae_Br4923 HALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNS-----------
Mb0393|M.bovis_AF2122/97 GGRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVS
Rv0386|M.tuberculosis_H37Rv GGRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVS
TH_3225|M.thermoresistible__bu ----------------------TYAVGELAGGFVSPGAGSAPSRIEENYV
Mvan_5002|M.vanbaalenii_PYR-1 ----------------------NHVGTELPGSAATPGSRPLARRLEQSYA
MSMEG_0321|M.smegmatis_MC2_155 ----------------------TIPAAELAGGFSTIAGRRSAGRVEDSFT
MAB_3361|M.abscessus_ATCC_1997 ----------------------DMTAEELAGGFGWPDGGRLAGQIEQTFL
MMAR_0085|M.marinum_M ----------------------ALIRGELAGGYGLANATRTETQIERTFV
Mflv_4504|M.gilvum_PYR-GCK -------------------------THVNSGDSPPAAEPPLPATLADVVR
MUL_2555|M.ulcerans_Agy99 --------------------------------------------MPALSA
MAV_0578|M.avium_104 ------------------DQMAAGRMRRVAGVWMWDGDVAVSASLSDTVG
MLBr_02341|M.leprae_Br4923 -------------------------GQVIVGEIGSSALGYTAVGVQVGMA
:
Mb0393|M.bovis_AF2122/97 YRVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLA
Rv0386|M.tuberculosis_H37Rv YRVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLA
TH_3225|M.thermoresistible__bu HRIRALPAQTRRLLLIAAAEPIGDSALFLR----------AAALMGIAVD
Mvan_5002|M.vanbaalenii_PYR-1 RRIKALPPQTQLLLLAAAAEPVGDAAVLIR----------AAAQLGIAVD
MSMEG_0321|M.smegmatis_MC2_155 SRVRSLPDEARQLLLLAAAEPIGDAALFVR----------AAAHLGVAVP
MAB_3361|M.abscessus_ATCC_1997 RRVQQLPAHTQTLLLAAATDPLGDVTLLAR----------AAQQLGIPMH
MMAR_0085|M.marinum_M SRLRALPSETKTFLLVAAAESTARPEWLWA----------AAHRLGIGPE
Mflv_4504|M.gilvum_PYR-GCK RRVGLLDDATRTLLLGVACVADPTVELLAR---------AHGASTDEITA
MUL_2555|M.ulcerans_Agy99 NLVASIDRHPERITLRCDDLQSVFAELGAG--------------------
MAV_0578|M.avium_104 RQLGRLTPPLALVVDTLSQCEPLPVDLLCD-----------LASREDLVA
MLBr_02341|M.leprae_Br4923 QRMESVAPPGVVMLSESTARLVEQTAVLGAP---------QTVRIKGAED
: : .
Mb0393|M.bovis_AF2122/97 IELAAARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYT
Rv0386|M.tuberculosis_H37Rv IELAAARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYT
TH_3225|M.thermoresistible__bu ALAPAEAARVIQFGPRMR-FFHPLMRSAAYRAADPRDRRAVHRALAEATD
Mvan_5002|M.vanbaalenii_PYR-1 MLTPAEAAGVIELGTRVR-FRHPLVRSAAYQAADLADRRTVHRALAEATD
MSMEG_0321|M.smegmatis_MC2_155 ALAPAESAGLIEFGTRIR-FHHPLVRSAAYRAASVEDRRAAHHALAEATD
MAB_3361|M.abscessus_ATCC_1997 AIAPAEAADLVELSTRVR-FRHPLVRSAVYISANPLERRRIHGVLAGATD
MMAR_0085|M.marinum_M AAAPAEAAGLIAAQGSVR-FRHPLIRAAVYHSSSAAERRRVHAALAASIA
Mflv_4504|M.gilvum_PYR-GCK GLERAEAAGIVVLEGNRVRFTHPLLAGGVYTDAGPTARRAMHRAIASVES
MUL_2555|M.ulcerans_Agy99 ---PGDRVAALPGDRTRRRVCGPACELSGGRFRPSAR-------------
MAV_0578|M.avium_104 AEAMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLATRLA
MLBr_02341|M.leprae_Br4923 AVPARRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVG
Mb0393|M.bovis_AF2122/97 LLTEPERTLFRR-LAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDK
Rv0386|M.tuberculosis_H37Rv LLTEPERTLFRR-LAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDK
TH_3225|M.thermoresistible__bu PGADPDRRAWHA-ANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLER
Mvan_5002|M.vanbaalenii_PYR-1 SATDPDRRAWHA-ANAATGPDDAVAAELEASAARAQARGGVAAAAAFLER
MSMEG_0321|M.smegmatis_MC2_155 AVTDPDRRAWHA-ANAAAGPSDAVATELEASAGRAQTRGGIAAAATFLER
MAB_3361|M.abscessus_ATCC_1997 PGADPDRRAWHR-AHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQR
MMAR_0085|M.marinum_M GPDDDDHRVWHR-AHAAEAPDAQTADDLERSAERARARGGLSAAASFLEH
Mflv_4504|M.gilvum_PYR-GCK ---HPELRARHL-ALAASSGDDEIFAALDQAADSARARGAPAAAAELMDL
MUL_2555|M.ulcerans_Agy99 ----PQSCPGLT-EAASPGRSRGPLHLARCAAELTIRRGDACQAIELLRR
MAV_0578|M.avium_104 QDQDADMQATVRRALLTLESDLDPQPELYLESARHAMTLLDLDLADRLAN
MLBr_02341|M.leprae_Br4923 LVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRA
. :
Mb0393|M.bovis_AF2122/97 SLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAA
Rv0386|M.tuberculosis_H37Rv SLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAA
TH_3225|M.thermoresistible__bu AVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERA---------
Mvan_5002|M.vanbaalenii_PYR-1 AAALTSDPALRGARALAAAQAKRDAAAPAEAQELLSTAELG---------
MSMEG_0321|M.smegmatis_MC2_155 AAVLSADLHLRGARAVAAAQAKRDAADLQAAYELLAIAELS---------
MAB_3361|M.abscessus_ATCC_1997 ATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMT---------
MMAR_0085|M.marinum_M ATKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAA---------
Mflv_4504|M.gilvum_PYR-GCK ALGLGAHDPMRRLKAAENHFLAGDTAKAAAALGEVGSIEPP---------
MUL_2555|M.ulcerans_Agy99 AGELSDRPRRREQLLASAAFVALQAAQLDEAERLLADAGLG---------
MAV_0578|M.avium_104 AAARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGD---------
MLBr_02341|M.leprae_Br4923 VAQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADP----------
Mb0393|M.bovis_AF2122/97 RVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRV
Rv0386|M.tuberculosis_H37Rv RVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRV
TH_3225|M.thermoresistible__bu -----------PLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAAL
Mvan_5002|M.vanbaalenii_PYR-1 -----------RLSELQQAQAARLRAQMEFTRRRGGDTGARPLDETASQL
MSMEG_0321|M.smegmatis_MC2_155 -----------PLSDLQRAQIARLRAQMEFSHSRREDSGPAQLRDAAAML
MAB_3361|M.abscessus_ATCC_1997 -----------PLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGL
MMAR_0085|M.marinum_M -----------ADDELIAARCELIRAKIAFAASRGSD--------APPLL
Mflv_4504|M.gilvum_PYR-GCK ---------------ILRAMATSLLATVRMYDN---------------EH
MUL_2555|M.ulcerans_Agy99 --------------GGASASALLISSFISLYRYG----------DVTATH
MAV_0578|M.avium_104 -------------ASDRHYWATVRAANLVWMLGRP--------ADAALVL
MLBr_02341|M.leprae_Br4923 ----------------------------------------------AVEL
Mb0393|M.bovis_AF2122/97 WMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAA
Rv0386|M.tuberculosis_H37Rv WMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAA
TH_3225|M.thermoresistible__bu LTAAQLLQD----VDAPAARE--SYLEAFAALMYAGRLA--PSGALLEAA
Mvan_5002|M.vanbaalenii_PYR-1 LTAAASFEQ----LDGYVSRE--AYLEALAAAMFAGRLG--DPGAVPRIA
MSMEG_0321|M.smegmatis_MC2_155 LDAARRLES----LDDELALQ--THLEAIAAAMYAGHLG--APDALLTTA
MAB_3361|M.abscessus_ATCC_1997 VEAARCLEN----LDDNLARE--TYLDAVGAAMYGGRLC--PRGGAVEVA
MMAR_0085|M.marinum_M LAAAQRMQR----LDPSESRK--AYLGAVLASILVGRMATDQHNSSPSVA
Mflv_4504|M.gilvum_PYR-GCK RQAVDLLRS---ALDDAADNVPVQVQVLLRLSFALNSIG--ELDDARRYA
MUL_2555|M.ulcerans_Agy99 RRLVERLQS----ADDLDGETLTRMVNLLLAVSMFAADP--------ALW
MAV_0578|M.avium_104 DGLAARPETP---AQAAARCAVQACLDAVAARCQLAAER-------ARAA
MLBr_02341|M.leprae_Br4923 PRLDPDARR--------------RRLTALINVAQLALSR-----------
.
Mb0393|M.bovis_AF2122/97 AGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAI
Rv0386|M.tuberculosis_H37Rv AGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAI
TH_3225|M.thermoresistible__bu DAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELA
Mvan_5002|M.vanbaalenii_PYR-1 AAASAALDRLPESARPVDALLRGIVARITGGVSAGAAPLRLAMDLMQEQA
MSMEG_0321|M.smegmatis_MC2_155 AAAQAAVDRLASRDDPIALLLDGVAKCLTGDVGDAAVPLRKALTAWCSAA
MAB_3361|M.abscessus_ATCC_1997 EPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEA
MMAR_0085|M.marinum_M KAASNAPA-APHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRER
Mflv_4504|M.gilvum_PYR-GCK RDAVKLAEELGFPGATSAALAWAVHVDFQCGRGLDETALARAMKLYDSTF
MUL_2555|M.ulcerans_Agy99 QITDGLVDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDRLAE--
MAV_0578|M.avium_104 LDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEAS-
MLBr_02341|M.leprae_Br4923 -PAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEY-------
Mb0393|M.bovis_AF2122/97 DLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHS
Rv0386|M.tuberculosis_H37Rv DLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHS
TH_3225|M.thermoresistible__bu RSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDAGALA
Mvan_5002|M.vanbaalenii_PYR-1 RNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRARDAGALE
MSMEG_0321|M.smegmatis_MC2_155 QHGDGAVLPWIFVGYPIVQESAVDELWDDTLMERLADAMVRYTRDAGALA
MAB_3361|M.abscessus_ATCC_1997 DR--PANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVGALS
MMAR_0085|M.marinum_M DIG------VAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAAGALT
Mflv_4504|M.gilvum_PYR-GCK DVP-------IIFRAPFVHALAMSWTGRLEQAHQELTAVRGVCLERGAES
MUL_2555|M.ulcerans_Agy99 ----------LEPWDVMRVALAGYYVDLIDDFRSVLVPLADREIEGGAAT
MAV_0578|M.avium_104 ---------HMRFWFGAVYGRACRLTGRIDEFVSTARRLADSARDVPGLA
MLBr_02341|M.leprae_Br4923 -----------HGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQ
Mb0393|M.bovis_AF2122/97 NALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLA
Rv0386|M.tuberculosis_H37Rv NALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLA
TH_3225|M.thermoresistible__bu GLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHRL---
Mvan_5002|M.vanbaalenii_PYR-1 ALPQVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYTPVRYQTL---
MSMEG_0321|M.smegmatis_MC2_155 ILPAALSCRAGAHLLSGEFGTAGNLLDEANAIAVAIADQ-PLRYHRL---
MAB_3361|M.abscessus_ATCC_1997 LLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGHA-PIRYHSL---
MMAR_0085|M.marinum_M MLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATGAP-PRPAIKT---
Mflv_4504|M.gilvum_PYR-GCK DMMAIAGFLAINHLWRGQITDAEAEAAEAVERAEQLGGDDVLIIPMTVRG
MUL_2555|M.ulcerans_Agy99 IALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRGYLG
MAV_0578|M.avium_104 YANLALLLGN-AELARGAAAEAARLVQEALAGAQIHEVTSGLRPASY--F
MLBr_02341|M.leprae_Br4923 IGELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPAT
.
Mb0393|M.bovis_AF2122/97 FALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTA
Rv0386|M.tuberculosis_H37Rv FALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTA
TH_3225|M.thermoresistible__bu IIAAWRGDAVEAARLIEAAAADGEA-------------------------
Mvan_5002|M.vanbaalenii_PYR-1 TLAAWRGEPADAEAVIEAAIADANA-------------------------
MSMEG_0321|M.smegmatis_MC2_155 HLAAWRGSTAETIAMIDSATAMAHR-------------------------
MAB_3361|M.abscessus_ATCC_1997 ILAAWRGSEPTAIRLIDEAMRDGAA-------------------------
MMAR_0085|M.marinum_M YLAAYRGQEQICREGVQQTVDSAAS-------------------------
Mflv_4504|M.gilvum_PYR-GCK AIAAYAGRVDDARADARWVLAAVRN-------------------------
MUL_2555|M.ulcerans_Agy99 VISACRGDVVRARELAAQVRVWAEP-------------------------
MAV_0578|M.avium_104 ALAEAHGRLGHPAQANEAIAGARSCVP-----------------------
MLBr_02341|M.leprae_Br4923 LQATIAARIDRLSPPAKQLLVAAAV-------------------------
.
Mb0393|M.bovis_AF2122/97 QHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQS-
Rv0386|M.tuberculosis_H37Rv QHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQS-
TH_3225|M.thermoresistible__bu --------RGEGRLMGLTGYAAALLYNGIGRYREALAAARTTCEYEDLG-
Mvan_5002|M.vanbaalenii_PYR-1 --------RGEGRVLGAADYAFAVLYNGLGRYQEACSAARRACEYEDLG-
MSMEG_0321|M.smegmatis_MC2_155 --------NGEGRLLAVLGYFAALLYNGAGRYEEAYAAIRPACSTKNLG-
MAB_3361|M.abscessus_ATCC_1997 --------RGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACEHEDLG-
MMAR_0085|M.marinum_M --------RGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGARYDDVG-
Mflv_4504|M.gilvum_PYR-GCK --------RKASHIADWPGMTLCFLEESLGNHREALAALDDSFIAAGPPT
MUL_2555|M.ulcerans_Agy99 --------RRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITAPGEFPP
MAV_0578|M.avium_104 --------PDFLFMHTGLALATGWALAAGGQLREAVATAQAAARLARDR-
MLBr_02341|M.leprae_Br4923 ----------IGFRFGSDLLASLGIDLSVDELIDANLVDQVRFTAPVEY-
Mb0393|M.bovis_AF2122/97 ---MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLP
Rv0386|M.tuberculosis_H37Rv ---MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLP
TH_3225|M.thermoresistible__bu ---FYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWGLGALAG
Mvan_5002|M.vanbaalenii_PYR-1 ---VHSWVLAELVEAADHCGDTALAVSALERLQERTADTGTDWGLGTLAG
MSMEG_0321|M.smegmatis_MC2_155 ---FGGWSLVELIEAAVHTGRREAAEEAADRLAAQAGASGTDWGLGALAG
MAB_3361|M.abscessus_ATCC_1997 ---LYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVAR
MMAR_0085|M.marinum_M ---MCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALGIGAS
Mflv_4504|M.gilvum_PYR-GCK TELMYAWHLPDAIEAMVGVGRLDDAEILTAALERNGVEHDRRWMRAVGAR
MUL_2555|M.ulcerans_Agy99 LALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRLAIATGA
MAV_0578|M.avium_104 ---------GQPTHELACIQAAAQWGDAAGAVRARALADALSLPLADAIA
MLBr_02341|M.leprae_Br4923 ----------AFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVD
Mb0393|M.bovis_AF2122/97 DVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYV
Rv0386|M.tuberculosis_H37Rv DVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYV
TH_3225|M.thermoresistible__bu ARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREH
Mvan_5002|M.vanbaalenii_PYR-1 AQALVADDD----HAEALFEESIDRLARTRVAVHLARAHLRYGEWLRRAL
MSMEG_0321|M.smegmatis_MC2_155 ARAMLADHD----TADALFTEAIERLQRTRIAVELARTHLRYGEWLRRVN
MAB_3361|M.abscessus_ATCC_1997 SRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCN
MMAR_0085|M.marinum_M ATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLTYGEWLRRER
Mflv_4504|M.gilvum_PYR-GCK CRAMLLAAHGDVAAAEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLR
MUL_2555|M.ulcerans_Agy99 AEALCASDE----RAPALFEKVLGHPAVASFPFEHARIRLAYGMRLRRLR
MAV_0578|M.avium_104 CHAEALRAG----NGEALLTVAAAYRAIGDAAAAADAAAQASAAFVEG-Q
MLBr_02341|M.leprae_Br4923 QHAVLIAEH-----------LEAAGDLHAAYGWHMRAAAWATNQDVRAAR
Mb0393|M.bovis_AF2122/97 QSVTALRDAMGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWES
Rv0386|M.tuberculosis_H37Rv QSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWES
TH_3225|M.thermoresistible__bu RRGEARRELNEAHGMFTRMGA-QGFAERSRRELIAVGEKVRRQPLTSGDE
Mvan_5002|M.vanbaalenii_PYR-1 RRNDAREQLTLASGMFTRFGA-AAFAERTRRELIATGEKARRQPVTSGAQ
MSMEG_0321|M.smegmatis_MC2_155 RRPDARRHLGVAFDMFTRMGA-AGFAERARRELTATGEKVRKQPVSSGDE
MAB_3361|M.abscessus_ATCC_1997 RRSDARTELTAAHGSFVNMGT-AAFAERAERELRATGAKVRKRSASSEKA
MMAR_0085|M.marinum_M RRSEARSQLRIAYDMFAQMGA-AGFAERARRELSATGEAVYVQPTGITVD
Mflv_4504|M.gilvum_PYR-GCK QKATAAKNLTDALHTFEQLGT-PLWAQRARSELAR-------AVVAPAEG
MUL_2555|M.ulcerans_Agy99 RYRNARVVLRAAAEIFAGLGA-EPWTQRARNELRAAGTAVRHSAAVGPAP
MAV_0578|M.avium_104 QHQRGRYAAALAGELAEECGGLCTPALR----------------TPAGLK
MLBr_02341|M.leprae_Br4923 VSWEHATKIADALTAEDPHRAAMCIAPRTR---------------LCGIA
: :
Mb0393|M.bovis_AF2122/97 LTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQ
Rv0386|M.tuberculosis_H37Rv LTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQ
TH_3225|M.thermoresistible__bu LTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQ
Mvan_5002|M.vanbaalenii_PYR-1 LTAQESQIARLAGDGLTNQEIGAQLFISTHTVDWHLRKVFVKLGITSRRQ
MSMEG_0321|M.smegmatis_MC2_155 LTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWHLRKVFVKLGIGSRRQ
MAB_3361|M.abscessus_ATCC_1997 LTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQ
MMAR_0085|M.marinum_M LTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRE
Mflv_4504|M.gilvum_PYR-GCK LTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTRIYRKLGISSRAE
MUL_2555|M.ulcerans_Agy99 LTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAG
MAV_0578|M.avium_104 LSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDE
MLBr_02341|M.leprae_Br4923 WRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDRLH-----
: . :: ** : :
Mb0393|M.bovis_AF2122/97 LAQAAARRT------
Rv0386|M.tuberculosis_H37Rv LAQAAARRT------
TH_3225|M.thermoresistible__bu LRAAPRVTATW----
Mvan_5002|M.vanbaalenii_PYR-1 LRSASWAS-------
MSMEG_0321|M.smegmatis_MC2_155 LRTIEWAG-------
MAB_3361|M.abscessus_ATCC_1997 LRSGR----------
MMAR_0085|M.marinum_M LRAILMESP------
Mflv_4504|M.gilvum_PYR-GCK LGRRMDQPGL-----
MUL_2555|M.ulcerans_Agy99 LHDALDAIHAAPDQI
MAV_0578|M.avium_104 LATIIRSRPAGRES-
MLBr_02341|M.leprae_Br4923 ---------------