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VDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRTGASRSLVLRGEAGIGKTALLDHVVAQAEGFRT TYVAGVESDMELAFAGLHQLCAPLLTHLDELPDPQRDALTVAFGQGAGATPDRFLVGLAVLSLMAAASTG GPLLCVIDDAQWLDQVSVQTLAFVARRLLAEPIAMVFAARDTGAEALSGLPELAVPGLSDGEARDLLDSV VVGRLDDRVRDRIIAETRGNPLALLDLPHNHVGTELPGSAATPGSRPLARRLEQSYARRIKALPPQTQLL LLAAAAEPVGDAAVLIRAAAQLGIAVDMLTPAEAAGVIELGTRVRFRHPLVRSAAYQAADLADRRTVHRA LAEATDSATDPDRRAWHAANAATGPDDAVAAELEASAARAQARGGVAAAAAFLERAAALTSDPALRGARA LAAAQAKRDAAAPAEAQELLSTAELGRLSELQQAQAARLRAQMEFTRRRGGDTGARPLDETASQLLTAAA SFEQLDGYVSREAYLEALAAAMFAGRLGDPGAVPRIAAAASAALDRLPESARPVDALLRGIVARITGGVS AGAAPLRLAMDLMQEQARNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRARDAGALEALP QVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYTPVRYQTLTLAAWRGEPADAEAVIEAAIADANAR GEGRVLGAADYAFAVLYNGLGRYQEACSAARRACEYEDLGVHSWVLAELVEAADHCGDTALAVSALERLQ ERTADTGTDWGLGTLAGAQALVADDDHAEALFEESIDRLARTRVAVHLARAHLRYGEWLRRALRRNDARE QLTLASGMFTRFGAAAFAERTRRELIATGEKARRQPVTSGAQLTAQESQIARLAGDGLTNQEIGAQLFIS THTVDWHLRKVFVKLGITSRRQLRSASWAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | - | 100% (940) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_1214 | - | 0.0 | 64.25% (923) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5449 | - | 0.0 | 48.86% (923) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 1e-17 | 28.60% (507) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 4e-62 | 28.12% (939) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0386 | - | 6e-17 | 28.40% (507) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 8e-16 | 26.89% (476) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 55.78% (891) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 0.0 | 46.20% (920) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 2e-15 | 24.35% (961) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 0.0 | 61.93% (922) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 63.07% (918) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 6e-33 | 28.67% (558) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Mvan_5002|M.vanbaalenii_PYR-1 ------------MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRT
TH_3225|M.thermoresistible__bu ----------------MSSRD-----GDVVLHGRAAEIATLRDVMSTARA
MSMEG_0321|M.smegmatis_MC2_155 ----------------METGG-----RGQPLHGRAAECDALRRSIADVQS
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M -------------------------MPTVTLVGRHREQQQLQQLLDAARR
Mflv_1156|M.gilvum_PYR-GCK -------------------------------------MKAVDDFLAGLQQ
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ------------------------MIGGELLIGRDSELAAIRRALNGADH
MLBr_02341|M.leprae_Br4923 ----------------------------------------MTTALVCVAC
Mb0393|M.bovis_AF2122/97 GVRPVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGE
Rv0386|M.tuberculosis_H37Rv GVRPVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGE
Mvan_5002|M.vanbaalenii_PYR-1 GASRSLVLRGEAGIGKTALLDHVVAQA--EGFRTTYVAGVESDM-----E
TH_3225|M.thermoresistible__bu GSSRVLVLHGEAGVGKTALLGQLLGDA--AGMRCVQVAGVESDM-----E
MSMEG_0321|M.smegmatis_MC2_155 AQSRVLVLRGEAGVGKTALLDFAAQHA--KGFRITQVAGVESDM-----E
MAB_3361|M.abscessus_ATCC_1997 ------MLRGQAGVGKTALLRYVLGKA--SGQLIAQASGIQSEM-----E
MMAR_0085|M.marinum_M GESGVLVLRGDAGIGKTTLLTDLVDNA--PDLRVLRVRGAEMEM-----E
Mflv_1156|M.gilvum_PYR-GCK LQPAGLLIEGEAGIGKTTMLAGVVDAARQAGFRVLSAHGDQSGS-----G
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 HRG--VVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQ-----A
MLBr_02341|M.leprae_Br4923 GAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVG-----------
Mb0393|M.bovis_AF2122/97 VALRDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKA
Rv0386|M.tuberculosis_H37Rv VALRDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKA
Mvan_5002|M.vanbaalenii_PYR-1 LAFAGLHQLCA-PLLTHLDELPDPQRDALT--VAFGQGAGATPDRFLVGL
TH_3225|M.thermoresistible__bu LAYAGLHQLCA-PLLDRLDDLPSPQRDVLN--VAFGRGAGPAPGRFLVGL
MSMEG_0321|M.smegmatis_MC2_155 LAYAGLQQLCA-PLMNNLDDLPEPQRDALA--VAFGLGVGQTPDRFLVGL
MAB_3361|M.abscessus_ATCC_1997 LAFAGLQQFCA-PLTKYSGAIPDPQREALT--IAFGTRSGPPPDRFLIGL
MMAR_0085|M.marinum_M LTYSGVQQLCG-PLMSLIGQLPEPQLDALE--IALGRKRGRAPDRLLLGL
Mflv_1156|M.gilvum_PYR-GCK LAHAAIADLFAGVQTDILDGLPELQRRAADGVLRRGDGTGGPTDERVIAA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LPLGAFIGLLG-------DAMSEPLTSVRR--------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 WLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLT
Rv0386|M.tuberculosis_H37Rv WLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLT
Mvan_5002|M.vanbaalenii_PYR-1 AVLSLMAAASTGGP-----------------LLCVIDDAQWLDQVSVQTL
TH_3225|M.thermoresistible__bu AVLNLLAAAGADQP-----------------LLCVIDDAQWLDRVSLQTL
MSMEG_0321|M.smegmatis_MC2_155 AVLSLMAAAADEKP-----------------LLCIVDDAQWLDSVSVQTL
MAB_3361|M.abscessus_ATCC_1997 AVLSLLAAAAEHQP-----------------VLCVIDDAQWLDRVSLQTL
MMAR_0085|M.marinum_M AVLTLVGEASRASP-----------------ILCVVDDAQWVDSASVQAL
Mflv_1156|M.gilvum_PYR-GCK ALLGAVHGSATRTP-----------------VLVAVDDVQWLDPSSVAVL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 VIETFVARQR-RGR-----------------VVVGVDDAHLLDGLSALVV
MLBr_02341|M.leprae_Br4923 --------------------------------SMDIAAAVGLERLREIMT
Mb0393|M.bovis_AF2122/97 RFVGRGAQITEVHRLVTDNRLVTLT----------GAGGVGKTRLAAQLA
Rv0386|M.tuberculosis_H37Rv RFVGRGAQITEVHRLVTDNRLVTLT----------GAGGVGKTRLAAQLA
Mvan_5002|M.vanbaalenii_PYR-1 AFVAR-RLLAEPIAMVFAARDTGAE----------ALSGLPELAVPGLSD
TH_3225|M.thermoresistible__bu GFVAR-RLMAEPVAMVFALRDDIHE----------ALVGVPALAVPGLAD
MSMEG_0321|M.smegmatis_MC2_155 AFVAR-RLLAEPVGLIFAVRDHGAP----------ALAGLPELLVDGLSD
MAB_3361|M.abscessus_ATCC_1997 AFVTR-RLGSEPVAMLFAVRDGTDS----------ELAGLPELTVHGLRA
MMAR_0085|M.marinum_M AFVAR-RIHVDPVAMVFATRDRGPD----------ALTGHCELSLQGLED
Mflv_1156|M.gilvum_PYR-GCK AFVAR--RVKGRVGFVVAERPGVGPGLPAATWLQVGTGALTRLPVAPMSL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 HQLAQ----SGGVRLVVTVRTGSHQP--DAVTALWKDDLLTRLDLEPLSA
MLBr_02341|M.leprae_Br4923 ELVSR-------AAGVIERYGGTVD----------KFTGDGIMAIFGAPT
Mb0393|M.bovis_AF2122/97 AQIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFL
Rv0386|M.tuberculosis_H37Rv AQIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFL
Mvan_5002|M.vanbaalenii_PYR-1 GEARDLLDSVVVGRLDDRVRDRIIAETRGNPLALLDLPH-----------
TH_3225|M.thermoresistible__bu ADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPR-----------
MSMEG_0321|M.smegmatis_MC2_155 TDARELLDSVILGRLDERVRDRVVAETRGIPLALLEVPR-----------
MAB_3361|M.abscessus_ATCC_1997 ADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPR-----------
MMAR_0085|M.marinum_M HDARLVLSTAIPGRLNDSVAETVLAEANGNPLALLELHN-----------
Mflv_1156|M.gilvum_PYR-GCK GALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALELAR-----------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 AATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLS-----------
MLBr_02341|M.leprae_Br4923 ALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVG----------
Mb0393|M.bovis_AF2122/97 GGRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVS
Rv0386|M.tuberculosis_H37Rv GGRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVS
Mvan_5002|M.vanbaalenii_PYR-1 ----------------------NHVGTELPGSAATPGSRPLARRLEQSYA
TH_3225|M.thermoresistible__bu ----------------------TYAVGELAGGFVSPGAGSAPSRIEENYV
MSMEG_0321|M.smegmatis_MC2_155 ----------------------TIPAAELAGGFSTIAGRRSAGRVEDSFT
MAB_3361|M.abscessus_ATCC_1997 ----------------------DMTAEELAGGFGWPDGGRLAGQIEQTFL
MMAR_0085|M.marinum_M ----------------------ALIRGELAGGYGLANATRTETQIERTFV
Mflv_1156|M.gilvum_PYR-GCK ----------------------------VADGAGSRPGQRLPESLSELVR
MUL_2555|M.ulcerans_Agy99 --------------------------------------------MPALSA
MAV_0578|M.avium_104 ------------------DQMAAGRMRRVAGVWMWDGDVAVSASLSDTVG
MLBr_02341|M.leprae_Br4923 ----------------------LNSGQVIVGEIGSSALGYTAVGVQVGMA
:
Mb0393|M.bovis_AF2122/97 YRVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLA
Rv0386|M.tuberculosis_H37Rv YRVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLA
Mvan_5002|M.vanbaalenii_PYR-1 RRIKALPPQTQLLLLAAAAEPVGDAAVLIR----------AAAQLGIAVD
TH_3225|M.thermoresistible__bu HRIRALPAQTRRLLLIAAAEPIGDSALFLR----------AAALMGIAVD
MSMEG_0321|M.smegmatis_MC2_155 SRVRSLPDEARQLLLLAAAEPIGDAALFVR----------AAAHLGVAVP
MAB_3361|M.abscessus_ATCC_1997 RRVQQLPAHTQTLLLAAATDPLGDVTLLAR----------AAQQLGIPMH
MMAR_0085|M.marinum_M SRLRALPSETKTFLLVAAAESTARPEWLWA----------AAHRLGIGPE
Mflv_1156|M.gilvum_PYR-GCK LRVDGLAEDVRDVLLVAASATSPTVDLLAK---------AVGVTPAAVTG
MUL_2555|M.ulcerans_Agy99 NLVASIDRHPERITLRCDDLQSVFAELGAG--------------------
MAV_0578|M.avium_104 RQLGRLTPPLALVVDTLSQCEPLPVDLLCD---------------LASRE
MLBr_02341|M.leprae_Br4923 QRMESVAPPGVVMLSESTARLVEQTAVLGAP---------QTVRIKGAED
: : .
Mb0393|M.bovis_AF2122/97 IELAAARLRSMTLD----EIIDGLRDRFALLTGGARTAAHRQQTLWASVD
Rv0386|M.tuberculosis_H37Rv IELAAARLRSMTLD----EIIDGLRDRFALLTGGARTAAHRQQTLWASVD
Mvan_5002|M.vanbaalenii_PYR-1 MLTPAEAAGVIELG----TRVR-FRHPLVRSAAYQAADLADRRTVHRALA
TH_3225|M.thermoresistible__bu ALAPAEAARVIQFG----PRMR-FFHPLMRSAAYRAADPRDRRAVHRALA
MSMEG_0321|M.smegmatis_MC2_155 ALAPAESAGLIEFG----TRIR-FHHPLVRSAAYRAASVEDRRAAHHALA
MAB_3361|M.abscessus_ATCC_1997 AIAPAEAADLVELS----TRVR-FRHPLVRSAVYISANPLERRRIHGVLA
MMAR_0085|M.marinum_M AAAPAEAAGLIAAQ----GSVR-FRHPLIRAAVYHSSSAAERRRVHAALA
Mflv_1156|M.gilvum_PYR-GCK LVEAAEVEGIVVID----GNRIRFTHPVLANGIYAGADPQRRREVHRRLA
MUL_2555|M.ulcerans_Agy99 ---PGDRVAALPGD----RTRRRVCGPACELSGGRFRPSAR---------
MAV_0578|M.avium_104 DLVAAEAMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLA
MLBr_02341|M.leprae_Br4923 AVPARRLLRVAEPR----QPTWFSESTLVGREWELATLAAMLDRSIGGRG
.
Mb0393|M.bovis_AF2122/97 WSYTLLTEPERTLFRRLAVFVGCFFV-DDAQAVACSGDVQRYQVLDEITL
Rv0386|M.tuberculosis_H37Rv WSYTLLTEPERTLFRRLAVFVGCFFV-DDAQAVACSGDVQRYQVLDEITL
Mvan_5002|M.vanbaalenii_PYR-1 EATDSATDPDRRAWHAANAATGPDDA-VAAELEASAARAQARGGVAAAAA
TH_3225|M.thermoresistible__bu EATDPGADPDRRAWHAANGVTGTDDA-VAAELEKSAARAQQRGGIAATAT
MSMEG_0321|M.smegmatis_MC2_155 EATDAVTDPDRRAWHAANAAAGPSDA-VATELEASAGRAQTRGGIAAAAT
MAB_3361|M.abscessus_ATCC_1997 GATDPGADPDRRAWHRAHAAAGTDEA-IAWELEQSAGRAQAKGGVLAAAA
MMAR_0085|M.marinum_M ASIAGPDDDDHRVWHRAHAAEAPDAQ-TADDLERSAERARARGGLSAAAS
Mflv_1156|M.gilvum_PYR-GCK DLKT---DPELRARHLALASTVADET-TLTTLDAAADAARARGAPAAAAE
MUL_2555|M.ulcerans_Agy99 --------PQSCPGLTEAASPGRSRG-PLHLARCAAELTIRRGDACQAIE
MAV_0578|M.avium_104 TRLAQDQDADMQATVRRALLTLESDLDPQPELYLESARHAMTLLDLDLAD
MLBr_02341|M.leprae_Br4923 SVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQ
.
Mb0393|M.bovis_AF2122/97 LVDKSLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYT
Rv0386|M.tuberculosis_H37Rv LVDKSLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYT
Mvan_5002|M.vanbaalenii_PYR-1 FLERAAALTSDPALRGARALAAAQAKRDAAAPAEAQELLSTAELG-----
TH_3225|M.thermoresistible__bu FLERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERA-----
MSMEG_0321|M.smegmatis_MC2_155 FLERAAVLSADLHLRGARAVAAAQAKRDAADLQAAYELLAIAELS-----
MAB_3361|M.abscessus_ATCC_1997 FLQRATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMT-----
MMAR_0085|M.marinum_M FLEHATKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAA-----
Mflv_1156|M.gilvum_PYR-GCK LLEWAMQLGGDSVSR---RIRAAEHHVVAGDMRRAATLLEQALVD-----
MUL_2555|M.ulcerans_Agy99 LLRRAGELSDRPRRREQLLASAAFVALQAAQLDEAERLLADAGLG-----
MAV_0578|M.avium_104 RLANAAARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGD-----
MLBr_02341|M.leprae_Br4923 LVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADPA-----
: :
Mb0393|M.bovis_AF2122/97 ALAARVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASS
Rv0386|M.tuberculosis_H37Rv ALAARVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASS
Mvan_5002|M.vanbaalenii_PYR-1 ---------------RLSELQQAQAARLRAQMEFTRRRGGDTGARPLDET
TH_3225|M.thermoresistible__bu ---------------PLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQT
MSMEG_0321|M.smegmatis_MC2_155 ---------------PLSDLQRAQIARLRAQMEFSHSRREDSGPAQLRDA
MAB_3361|M.abscessus_ATCC_1997 ---------------PLDPLARARATRLRAKIAFAESRVGAFGSVTVSEA
MMAR_0085|M.marinum_M ---------------ADDELIAARCELIRAKIAFAASRG--------SDA
Mflv_1156|M.gilvum_PYR-GCK -------------------LRPGVLCAIALNLLAG-----------VRMV
MUL_2555|M.ulcerans_Agy99 ------------------GGASASALLISSFISLYR----------YGDV
MAV_0578|M.avium_104 -----------------ASDRHYWATVRAANLVWMLGRP--------ADA
MLBr_02341|M.leprae_Br4923 ----------------------VELPRLDPDARRRR-------------L
Mb0393|M.bovis_AF2122/97 LLRVWMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIF
Rv0386|M.tuberculosis_H37Rv LLRVWMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIF
Mvan_5002|M.vanbaalenii_PYR-1 ASQLLTAAASFEQ----LDGYVSRE--AYLEALAAAMFAGRLG--DPGAV
TH_3225|M.thermoresistible__bu AAALLTAAQLLQD----VDAPAARE--SYLEAFAALMYAGRLA--PSGAL
MSMEG_0321|M.smegmatis_MC2_155 AAMLLDAARRLES----LDDELALQ--THLEAIAAAMYAGHLG--APDAL
MAB_3361|M.abscessus_ATCC_1997 AIGLVEAARCLEN----LDDNLARE--TYLDAVGAAMYGGRLC--PRGGA
MMAR_0085|M.marinum_M PPLLLAAAQRMQR----LDPSESRK--AYLGAVLASILVGRMATDQHNSS
Mflv_1156|M.gilvum_PYR-GCK EDDYIRAVELLER----ARADADNDAVLVTTLLSLGFCLGMTG--SFTAQ
MUL_2555|M.ulcerans_Agy99 TATHRRLVERLQS-----ADDLDGETLTRMVNLLLAVS-------MFAAD
MAV_0578|M.avium_104 ALVLDGLAARPETP---AQAAARCAVQACLDAVAARCQLAAER-------
MLBr_02341|M.leprae_Br4923 TALINVAQLALSR-----PAVFVVEDVHWIDEVSDSMLADFLAVIPQTRS
.
Mb0393|M.bovis_AF2122/97 VDAAAGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYF
Rv0386|M.tuberculosis_H37Rv VDAAAGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYF
Mvan_5002|M.vanbaalenii_PYR-1 PRIAAAASAALDRLPESARPVDALLRGIVARITGGVSAGAAPLRLAMDLM
TH_3225|M.thermoresistible__bu LEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAM
MSMEG_0321|M.smegmatis_MC2_155 LTTAAAAQAAVDRLASRDDPIALLLDGVAKCLTGDVGDAAVPLRKALTAW
MAB_3361|M.abscessus_ATCC_1997 VEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLI
MMAR_0085|M.marinum_M PSVAKAASNAPA-APHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREY
Mflv_1156|M.gilvum_PYR-GCK LATVREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLRAVDLE
MUL_2555|M.ulcerans_Agy99 PALWQITDGLVDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDRL
MAV_0578|M.avium_104 ARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSF
MLBr_02341|M.leprae_Br4923 MALVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQI
Mb0393|M.bovis_AF2122/97 AEAIDLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAI
Rv0386|M.tuberculosis_H37Rv AEAIDLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAI
Mvan_5002|M.vanbaalenii_PYR-1 QEQARNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRARDA
TH_3225|M.thermoresistible__bu CELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDA
MSMEG_0321|M.smegmatis_MC2_155 CSAAQHGDGAVLPWIFVGYPIVQESAVDELWDDTLMERLADAMVRYTRDA
MAB_3361|M.abscessus_ATCC_1997 RCEADR--PANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREV
MMAR_0085|M.marinum_M LRERDIG------VAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAA
Mflv_1156|M.gilvum_PYR-GCK DPEDNTP-------IPFRASAARGLSLALTGRLAEADGQLAAVAQRSAQR
MUL_2555|M.ulcerans_Agy99 AELEPWD------------VMRVALAGYYVDLIDDFRSVLVPLADREIEG
MAV_0578|M.avium_104 EASHMR----------FWFGAVYGRACRLTGRIDEFVSTARRLADSARDV
MLBr_02341|M.leprae_Br4923 G------------------ELITERAAGNPFFAQEITRELAERGVLTGER
Mb0393|M.bovis_AF2122/97 GDHSNALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVL-HKANS
Rv0386|M.tuberculosis_H37Rv GDHSNALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVL-HKANS
Mvan_5002|M.vanbaalenii_PYR-1 GALEALPQVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYT-PVRYQ
TH_3225|M.thermoresistible__bu GALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRG-PVRYH
MSMEG_0321|M.smegmatis_MC2_155 GALAILPAALSCRAGAHLLSGEFGTAGNLLDEANAIAVAIADQ--PLRYH
MAB_3361|M.abscessus_ATCC_1997 GALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGHA--PIRYH
MMAR_0085|M.marinum_M GALTMLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATGAP--PRPAI
Mflv_1156|M.gilvum_PYR-GCK GAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSM-VIAFS
MUL_2555|M.ulcerans_Agy99 GAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYEL-FGYQL
MAV_0578|M.avium_104 PGLAYANLALLLGN-AELARGAAAEAARLVQEALAGAQIHEVTSGLRPAS
MLBr_02341|M.leprae_Br4923 GRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIG------
:
Mb0393|M.bovis_AF2122/97 LQGLAFALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAG
Rv0386|M.tuberculosis_H37Rv LQGLAFALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAG
Mvan_5002|M.vanbaalenii_PYR-1 TL---TLAAWRGEPADAEAVIEAAIADANA--------------------
TH_3225|M.thermoresistible__bu RL---IIAAWRGDAVEAARLIEAAAADGEA--------------------
MSMEG_0321|M.smegmatis_MC2_155 RL---HLAAWRGSTAETIAMIDSATAMAHR--------------------
MAB_3361|M.abscessus_ATCC_1997 SL---ILAAWRGSEPTAIRLIDEAMRDGAA--------------------
MMAR_0085|M.marinum_M KT---YLAAYRGQEQICREGVQQTVDSAAS--------------------
Mflv_1156|M.gilvum_PYR-GCK IC--AAVAAYRGREDQARDQAAGALAQGGD--------------------
MUL_2555|M.ulcerans_Agy99 RGYLGVISACRGDVVRARELAAQVRVWAEP--------------------
MAV_0578|M.avium_104 YFALAEAHGRLGHPAQANEAIAGARSCVPP--------------------
MLBr_02341|M.leprae_Br4923 FRFGSDLLASLGIDLSVDELIDANLVDQVR--------------------
. *
Mb0393|M.bovis_AF2122/97 DVQTAQHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDD
Rv0386|M.tuberculosis_H37Rv DVQTAQHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDD
Mvan_5002|M.vanbaalenii_PYR-1 -------------RGEGRVLGAADYAFAVLYNGLGRYQEACSAARRACEY
TH_3225|M.thermoresistible__bu -------------RGEGRLMGLTGYAAALLYNGIGRYREALAAARTTCEY
MSMEG_0321|M.smegmatis_MC2_155 -------------NGEGRLLAVLGYFAALLYNGAGRYEEAYAAIRPACST
MAB_3361|M.abscessus_ATCC_1997 -------------RGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACEH
MMAR_0085|M.marinum_M -------------RGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGARY
Mflv_1156|M.gilvum_PYR-GCK ---------------YVALTVWASATLAFLEVSRGNYEQALEAAEPLVDL
MUL_2555|M.ulcerans_Agy99 -------------RRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITAP
MAV_0578|M.avium_104 --------------DFLFMHTGLALATGWALAAGGQLREAVATAQAAARL
MLBr_02341|M.leprae_Br4923 ------------------FTAPVEYAFRHPLIRTVAYESQLKSDRARLHR
Mb0393|M.bovis_AF2122/97 AVQS-----MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESG
Rv0386|M.tuberculosis_H37Rv AVQS-----MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESG
Mvan_5002|M.vanbaalenii_PYR-1 EDLG-----VHSWVLAELVEAADHCGDTALAVSALERLQERTADTGTDWG
TH_3225|M.thermoresistible__bu EDLG-----FYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWG
MSMEG_0321|M.smegmatis_MC2_155 KNLG-----FGGWSLVELIEAAVHTGRREAAEEAADRLAAQAGASGTDWG
MAB_3361|M.abscessus_ATCC_1997 EDLG-----LYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWS
MMAR_0085|M.marinum_M DDVG-----MCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTA
Mflv_1156|M.gilvum_PYR-GCK YRDFPGTELMSACFMPDAIESLIAVGRLDEAEPLIAAFERNGAELDRPWQ
MUL_2555|M.ulcerans_Agy99 GEFPP-LALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRL
MAV_0578|M.avium_104 ARDR-----------GQPTHELACIQAAAQWGDAAGAVRARALADALSLP
MLBr_02341|M.leprae_Br4923 RLAA--------------AIEARAPHSVDQHAVLIAEHLEAAGDLHAAYG
Mb0393|M.bovis_AF2122/97 AHLDLPDVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAI
Rv0386|M.tuberculosis_H37Rv AHLDLPDVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAI
Mvan_5002|M.vanbaalenii_PYR-1 LGTLAGAQALVADDD----HAEALFEESIDRLARTRVAVHLARAHLRYGE
TH_3225|M.thermoresistible__bu LGALAGARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLTYGE
MSMEG_0321|M.smegmatis_MC2_155 LGALAGARAMLADHD----TADALFTEAIERLQRTRIAVELARTHLRYGE
MAB_3361|M.abscessus_ATCC_1997 QGMVARSRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGE
MMAR_0085|M.marinum_M LGIGASATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLTYGE
Mflv_1156|M.gilvum_PYR-GCK LAIGNRCRAMLLSATGDLDGALAAAERAMAEHARLPMPFERARSALTLGE
MUL_2555|M.ulcerans_Agy99 AIATGAAEALCASDE----RAPALFEKVLGHPAVASFPFEHARIRLAYGM
MAV_0578|M.avium_104 LADAIACHAEALRAG----NGEALLTVAAAYRAIGDAAAAADAAAQASAA
MLBr_02341|M.leprae_Br4923 WHMRAAAWATNQDVR-----AARVSWEHATKIADALTAEDPHRAAMCIAP
. .
Mb0393|M.bovis_AF2122/97 YRSDYVQSVTALRDAMGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRP
Rv0386|M.tuberculosis_H37Rv YRSDYVQSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRP
Mvan_5002|M.vanbaalenii_PYR-1 WLRRALRRNDAREQLTLASGMFTRFGA-AAFAERTRRELIATGEKARRQP
TH_3225|M.thermoresistible__bu WLRREHRRGEARRELNEAHGMFTRMGA-QGFAERSRRELIAVGEKVRRQP
MSMEG_0321|M.smegmatis_MC2_155 WLRRVNRRPDARRHLGVAFDMFTRMGA-AGFAERARRELTATGEKVRKQP
MAB_3361|M.abscessus_ATCC_1997 WLRRCNRRSDARTELTAAHGSFVNMGT-AAFAERAERELRATGAKVRKRS
MMAR_0085|M.marinum_M WLRRERRRSEARSQLRIAYDMFAQMGA-AGFAERARRELSATGEAVYVQP
Mflv_1156|M.gilvum_PYR-GCK VLRRLRRR-DAAAAVRDALAQFEELGV-PLWVARARIALSGLAVSG----
MUL_2555|M.ulcerans_Agy99 RLRRLRRYRNARVVLRAAAEIFAGLGA-EPWTQRARNELRAAGTAVRHSA
MAV_0578|M.avium_104 FVEG-QQHQRGRYAAALAGELAEECGGLCTPALR----------------
MLBr_02341|M.leprae_Br4923 RTRLCGIAWRGRFNSSSGFDEVRQLCN-----------------------
.
Mb0393|M.bovis_AF2122/97 ATGWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLG
Rv0386|M.tuberculosis_H37Rv ATGWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLG
Mvan_5002|M.vanbaalenii_PYR-1 VTSGAQLTAQESQIARLAGDGLTNQEIGAQLFISTHTVDWHLRKVFVKLG
TH_3225|M.thermoresistible__bu LTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLG
MSMEG_0321|M.smegmatis_MC2_155 VSSGDELTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWHLRKVFVKLG
MAB_3361|M.abscessus_ATCC_1997 ASSEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRG
MMAR_0085|M.marinum_M TGITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLG
Mflv_1156|M.gilvum_PYR-GCK SAVGSELTDSERRIAELAASGMSNRDVAETLFVSVKTIETNLSRVYRKLG
MUL_2555|M.ulcerans_Agy99 AVGPAPLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLG
MAV_0578|M.avium_104 TPAGLKLSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVG
MLBr_02341|M.leprae_Br4923 -------------------------ATGDKAPLAVATVGPAIDHVYQDRL
. :: *: : :
Mb0393|M.bovis_AF2122/97 FTSRLQLAQAAARRT------
Rv0386|M.tuberculosis_H37Rv FTSRLQLAQAAARRT------
Mvan_5002|M.vanbaalenii_PYR-1 ITSRRQLRSASWAS-------
TH_3225|M.thermoresistible__bu ITSRRQLRAAPRVTATW----
MSMEG_0321|M.smegmatis_MC2_155 IGSRRQLRTIEWAG-------
MAB_3361|M.abscessus_ATCC_1997 ITSRRQLRSGR----------
MMAR_0085|M.marinum_M VTSRRELRAILMESP------
Mflv_1156|M.gilvum_PYR-GCK IRSRAQLGRMLR---------
MUL_2555|M.ulcerans_Agy99 VTNRAGLHDALDAIHAAPDQI
MAV_0578|M.avium_104 AQSRDELATIIRSRPAGRES-
MLBr_02341|M.leprae_Br4923 H--------------------