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ANQGRGVRLRGRREECATLRALVGAADPDSGRVLVIRGEAGVGKTALLDYVHRQATDFQCARVAGVESDM ELAFAGLHQLCAPLLTHLDELPSPQRDALSVAFGRGVGPAPDRFLVGLAVLSLMSAAARSTPLLCVVDDA QWLDQVSVQTLGFVARRLLAEPVVMVFAVRDNADVLSGLPEMFVTGLPDGDARKLLESVVLGRIDDRVRD RILAETRGNPLALLQVPRNVSAAELAGGFGYTIARPSAGHIEEGFVRRIRSLPVKTRRLLLVAAAEPVGD PSLFLRAAEKLGIAVDELAPAEAAEVIEFGSRMRFHHPLARSATYRTADLTERREVHRVLADATDPELDP DRRAWHAAIAATGPDDAVADDLEASAWRAERRGGIAAAATFLEHAAILTSEPVKRGSRAIAAAQAKRDAA APDSASELLAIADLQPLSDLQRAQVARLRAQMEFSRSRGDEPGASQISQAAAQLRSAAERLETLDGELSR ETYLEALAAAMYASARCGDPGLLMSTAEGARRAVSRLDTLDHPADHLLSGLATLLVGGRREGADHLRTAL RMWCARAGERDGQDLRWLSLAFPIVHECCAAELYDDGLTHELADVMVRYARDVGALAVLPAALSYRAGIH VIAGEFNTAATLLDESDAISAAINYRPVKYHRLHLAAWRGVPADALALIEPATKEATAKGEGRLLGLAGY ASALLYNGLGRYQEAFQAARRTCEEVDLGFHGWCLVELIESAARIDELDEAASALHRLEERAADTGTEWG LGALAGAKALLADDEYADALFTEAIARLDQTRVAVHAARTRLCYGEWLRRRNRRPDARTQLGDAHEMFTR FGAQAYAERARRELTAAGEKVRTQPDGTGGELTAQETQIARLAAEGFTNQEIGAQLFISAHTAEWHLRKV FVKLGITSRRQLRSISWAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1214 | - | - | 100% (930) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 0.0 | 64.25% (923) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5449 | - | 0.0 | 46.24% (930) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 9e-12 | 29.39% (262) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 3e-60 | 30.78% (939) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0386 | - | 3e-11 | 25.58% (258) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 3e-11 | 24.67% (450) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 54.43% (891) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 0.0 | 45.57% (926) | transcriptional regulatory protein |
| M. avium 104 | MAV_2364 | - | 6e-15 | 23.45% (870) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 0.0 | 63.71% (926) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 60.09% (927) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 2e-32 | 29.72% (562) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Mvan_1214|M.vanbaalenii_PYR-1 ---MANQGRGVRLRGRRE--------ECATLRALVGAADPDSGRVLVIRG
MSMEG_0321|M.smegmatis_MC2_155 ---METGGRGQPLHGRAA--------ECDALRRSIADVQSAQSRVLVLRG
TH_3225|M.thermoresistible__bu ---MSSRDGDVVLHGRAA--------EIATLRDVMSTARAGSSRVLVLHG
MAB_3361|M.abscessus_ATCC_1997 ----------------------------------------------MLRG
MMAR_0085|M.marinum_M -------MPTVTLVGRHR--------EQQQLQQLLDAARRGESGVLVLRG
Mflv_1156|M.gilvum_PYR-GCK ---------------------------MKAVDDFLAGLQQLQPAGLLIEG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 ----------------------------MEFRRSLAALNNGEFHGVALVG
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
Rv0386|M.tuberculosis_H37Rv GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
Mvan_1214|M.vanbaalenii_PYR-1 -----EAGVGKTALLDYVHR-----QATDFQCARVAGVESDM-----ELA
MSMEG_0321|M.smegmatis_MC2_155 -----EAGVGKTALLDFAAQ-----HAKGFRITQVAGVESDM-----ELA
TH_3225|M.thermoresistible__bu -----EAGVGKTALLGQLLG-----DAAGMRCVQVAGVESDM-----ELA
MAB_3361|M.abscessus_ATCC_1997 -----QAGVGKTALLRYVLG-----KASGQLIAQASGIQSEM-----ELA
MMAR_0085|M.marinum_M -----DAGIGKTTLLTDLVD-----NAPDLRVLRVRGAEMEM-----ELT
Mflv_1156|M.gilvum_PYR-GCK -----EAGIGKTTMLAGVVD---AARQAGFRVLSAHGDQSGS-----GLA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 -----DGGVGKSTLARMLAKT---VESAGRTVRFALGTQTGW--------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 LRDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKAWL
Rv0386|M.tuberculosis_H37Rv LRDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKAWL
Mvan_1214|M.vanbaalenii_PYR-1 FAGLHQLCA-PLLTHLDELPSPQRDALS--VAFGRGVGPAPDRFLVGLAV
MSMEG_0321|M.smegmatis_MC2_155 YAGLQQLCA-PLMNNLDDLPEPQRDALA--VAFGLGVGQTPDRFLVGLAV
TH_3225|M.thermoresistible__bu YAGLHQLCA-PLLDRLDDLPSPQRDVLN--VAFGRGAGPAPGRFLVGLAV
MAB_3361|M.abscessus_ATCC_1997 FAGLQQFCA-PLTKYSGAIPDPQREALT--IAFGTRSGPPPDRFLIGLAV
MMAR_0085|M.marinum_M YSGVQQLCG-PLMSLIGQLPEPQLDALE--IALGRKRGRAPDRLLLGLAV
Mflv_1156|M.gilvum_PYR-GCK HAAIADLFAGVQTDILDGLPELQRRAADGVLRRGDGTGGPTDERVIAAAL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 --------------------AVPLGAFSRAVSLGVGHEP-------AIML
MLBr_02341|M.leprae_Br4923 ---------------------------------------------MTTAL
Mb0393|M.bovis_AF2122/97 VDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRF
Rv0386|M.tuberculosis_H37Rv VDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRF
Mvan_1214|M.vanbaalenii_PYR-1 LSLMSAAARSTP-----------------LLCVVDDAQWLDQVSVQTLGF
MSMEG_0321|M.smegmatis_MC2_155 LSLMAAAADEKP-----------------LLCIVDDAQWLDSVSVQTLAF
TH_3225|M.thermoresistible__bu LNLLAAAGADQP-----------------LLCVIDDAQWLDRVSLQTLGF
MAB_3361|M.abscessus_ATCC_1997 LSLLAAAAEHQP-----------------VLCVIDDAQWLDRVSLQTLAF
MMAR_0085|M.marinum_M LTLVGEASRASP-----------------ILCVVDDAQWVDSASVQALAF
Mflv_1156|M.gilvum_PYR-GCK LGAVHGSATRTP-----------------VLVAVDDVQWLDPSSVAVLAF
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 AAAHNTLGQDKN-----------------LVVVVDEAQLLDPLSATLVNQ
MLBr_02341|M.leprae_Br4923 VCVACGAELR------------------------SIAKFCDECGSPVVEA
Mb0393|M.bovis_AF2122/97 VGRGAQITEVHRLVTDNRLVTLTGAGG----------VGKTRLAAQLAAQ
Rv0386|M.tuberculosis_H37Rv VGRGAQITEVHRLVTDNRLVTLTGAGG----------VGKTRLAAQLAAQ
Mvan_1214|M.vanbaalenii_PYR-1 VAR-RLLAEPVVMVFAVRDN-ADVLSG----------LPEMFVTGLPDGD
MSMEG_0321|M.smegmatis_MC2_155 VAR-RLLAEPVGLIFAVRDHGAPALAG----------LPELLVDGLSDTD
TH_3225|M.thermoresistible__bu VAR-RLMAEPVAMVFALRDDIHEALVG----------VPALAVPGLADAD
MAB_3361|M.abscessus_ATCC_1997 VTR-RLGSEPVAMLFAVRDGTDSELAG----------LPELTVHGLRAAD
MMAR_0085|M.marinum_M VAR-RIHVDPVAMVFATRDRGPDALTG----------HCELSLQGLEDHD
Mflv_1156|M.gilvum_PYR-GCK VAR--RVKGRVGFVVAERPGVGPGLPAATWLQVGTGALTRLPVAPMSLGA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 LAAGRSARLIVTIRSGEPVLDAVTALLKER------LLLTVHVDPFTREQ
MLBr_02341|M.leprae_Br4923 ETPAEYKQVTVLFADVVGSMDIAAAVG----------LERLREIMTELVS
Mb0393|M.bovis_AF2122/97 IAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGG
Rv0386|M.tuberculosis_H37Rv IAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGG
Mvan_1214|M.vanbaalenii_PYR-1 ARKLLESVVLGRIDDRVRDRILAETRGNPLALLQVPR-------------
MSMEG_0321|M.smegmatis_MC2_155 ARELLDSVILGRLDERVRDRVVAETRGIPLALLEVPR-------------
TH_3225|M.thermoresistible__bu ARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPR-------------
MAB_3361|M.abscessus_ATCC_1997 AGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPR-------------
MMAR_0085|M.marinum_M ARLVLSTAIPGRLNDSVAETVLAEANGNPLALLELHN-------------
Mflv_1156|M.gilvum_PYR-GCK LHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALELAR-------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_2364|M.avium_104 TELLAGAVLGGPVDTRLVDELFERSAGNLLLLRGFLTAG-----------
MLBr_02341|M.leprae_Br4923 RAAGVIERYGGTVDKFTGDGIMAIFG------------------------
Mb0393|M.bovis_AF2122/97 RPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYR
Rv0386|M.tuberculosis_H37Rv RPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYR
Mvan_1214|M.vanbaalenii_PYR-1 --------------------NVSAAELAGGFGYTIARPSAGHIEEGFVRR
MSMEG_0321|M.smegmatis_MC2_155 --------------------TIPAAELAGGFSTIAGRRSAGRVEDSFTSR
TH_3225|M.thermoresistible__bu --------------------TYAVGELAGGFVSPGAGSAPSRIEENYVHR
MAB_3361|M.abscessus_ATCC_1997 --------------------DMTAEELAGGFGWPDGGRLAGQIEQTFLRR
MMAR_0085|M.marinum_M --------------------ALIRGELAGGYGLANATRTETQIERTFVSR
Mflv_1156|M.gilvum_PYR-GCK --------------------------VADGAGSRPGQRLPESLSELVRLR
MUL_2555|M.ulcerans_Agy99 ------------------------------------------MPALSANL
MAV_2364|M.avium_104 ------------------VESGALVHTEQGWQLQGPLRGDRELHDALEYR
MLBr_02341|M.leprae_Br4923 -------------------------------------APTALEDHALRAC
Mb0393|M.bovis_AF2122/97 VPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIE
Rv0386|M.tuberculosis_H37Rv VPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIE
Mvan_1214|M.vanbaalenii_PYR-1 IRSLPVKTRRLLLVAAAEPVGDPSLFLR----------AAEKLGIAVDEL
MSMEG_0321|M.smegmatis_MC2_155 VRSLPDEARQLLLLAAAEPIGDAALFVR----------AAAHLGVAVPAL
TH_3225|M.thermoresistible__bu IRALPAQTRRLLLIAAAEPIGDSALFLR----------AAALMGIAVDAL
MAB_3361|M.abscessus_ATCC_1997 VQQLPAHTQTLLLAAATDPLGDVTLLAR----------AAQQLGIPMHAI
MMAR_0085|M.marinum_M LRALPSETKTFLLVAAAESTARPEWLWA----------AAHRLGIGPEAA
Mflv_1156|M.gilvum_PYR-GCK VDGLAEDVRDVLLVAASATSPTVDLLAK---------AVGVTPAAVTGLV
MUL_2555|M.ulcerans_Agy99 VASIDRHPERITLRCDDLQSVFAELGAG----------------------
MAV_2364|M.avium_104 LQSLSSEEREVVEVLATAELLEWEILRD-----------ICDADAMASLE
MLBr_02341|M.leprae_Br4923 LAALGVQEKARRLAAEVGDRDGVDLQLR----------------------
: : .
Mb0393|M.bovis_AF2122/97 LAAARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLL
Rv0386|M.tuberculosis_H37Rv LAAARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLL
Mvan_1214|M.vanbaalenii_PYR-1 APAEAAEVIEFGSRMR-FHHPLARSATYRTADLTERREVHRVLADATDPE
MSMEG_0321|M.smegmatis_MC2_155 APAESAGLIEFGTRIR-FHHPLVRSAAYRAASVEDRRAAHHALAEATDAV
TH_3225|M.thermoresistible__bu APAEAARVIQFGPRMR-FFHPLMRSAAYRAADPRDRRAVHRALAEATDPG
MAB_3361|M.abscessus_ATCC_1997 APAEAADLVELSTRVR-FRHPLVRSAVYISANPLERRRIHGVLAGATDPG
MMAR_0085|M.marinum_M APAEAAGLIAAQGSVR-FRHPLIRAAVYHSSSAAERRRVHAALAASIAGP
Mflv_1156|M.gilvum_PYR-GCK EAAEVEGIVVIDGNRIRFTHPVLANGIYAGADPQRRREVHRRLADLKT--
MUL_2555|M.ulcerans_Agy99 -PGDRVAALPGDRTRRRVCGPACELSGGRFRPSAR---------------
MAV_2364|M.avium_104 RRGLIQLVTDGSHTLVQLNHPMLGEAATRHAGVVRSRQLNGILAKTLRKH
MLBr_02341|M.leprae_Br4923 -----VGLNSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLS
.
Mb0393|M.bovis_AF2122/97 TEPERTLFRRLAVF---VGCFFVDDAQAVACSGDVQRYQVLDEITLLVDK
Rv0386|M.tuberculosis_H37Rv TEPERTLFRRLAVF---VGCFFVDDAQAVACSGDVQRYQVLDEITLLVDK
Mvan_1214|M.vanbaalenii_PYR-1 LDPDRRAWHAAIAA---TGPDDAVADDLEASAWRAERRGGIAAAATFLEH
MSMEG_0321|M.smegmatis_MC2_155 TDPDRRAWHAANAA---AGPSDAVATELEASAGRAQTRGGIAAAATFLER
TH_3225|M.thermoresistible__bu ADPDRRAWHAANGV---TGTDDAVAAELEKSAARAQQRGGIAATATFLER
MAB_3361|M.abscessus_ATCC_1997 ADPDRRAWHRAHAA---AGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQR
MMAR_0085|M.marinum_M DDDDHRVWHRAHAA---EAPDAQTADDLERSAERARARGGLSAAASFLEH
Mflv_1156|M.gilvum_PYR-GCK -DPELRARHLALAS---TVADETTLTTLDAAADAARARGAPAAAAELLEW
MUL_2555|M.ulcerans_Agy99 --PQSCPGLTEAAS---PGRSRGPLHLARCAAELTIRRGDACQAIELLRR
MAV_2364|M.avium_104 LRAAGRRSQISDPRGRIQLAQFIMRSDLEPDLDVVIKAAADAMAMSNVVL
MLBr_02341|M.leprae_Br4923 ESTARLVEQTAVLG-------APQTVRIKGAEDAVPARRLLRVAEPRQPT
.
Mb0393|M.bovis_AF2122/97 SLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAA
Rv0386|M.tuberculosis_H37Rv SLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAA
Mvan_1214|M.vanbaalenii_PYR-1 AAILTSEPVKRGSRAIAAAQAKRDAAAPDSASELLAIADLQ---------
MSMEG_0321|M.smegmatis_MC2_155 AAVLSADLHLRGARAVAAAQAKRDAADLQAAYELLAIAELS---------
TH_3225|M.thermoresistible__bu AVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERA---------
MAB_3361|M.abscessus_ATCC_1997 ATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMT---------
MMAR_0085|M.marinum_M ATKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAA---------
Mflv_1156|M.gilvum_PYR-GCK AMQLGGDSVSR---RIRAAEHHVVAGDMRRAATLLEQALVD---------
MUL_2555|M.ulcerans_Agy99 AGELSDRPRRREQLLASAAFVALQAAQLDEAERLLADAGLG---------
MAV_2364|M.avium_104 GEQLATFAVDRGGGLAAALVLAEAVSWQGRGEEADSILLG----------
MLBr_02341|M.leprae_Br4923 WFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIG---------
.
Mb0393|M.bovis_AF2122/97 RVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRV
Rv0386|M.tuberculosis_H37Rv RVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRV
Mvan_1214|M.vanbaalenii_PYR-1 -----------PLSDLQRAQVARLRAQMEFSRSRGDEPGASQISQAAAQL
MSMEG_0321|M.smegmatis_MC2_155 -----------PLSDLQRAQIARLRAQMEFSHSRREDSGPAQLRDAAAML
TH_3225|M.thermoresistible__bu -----------PLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAAL
MAB_3361|M.abscessus_ATCC_1997 -----------PLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGL
MMAR_0085|M.marinum_M -----------ADDELIAARCELIRAKIAFAASRG--------SDAPPLL
Mflv_1156|M.gilvum_PYR-GCK ---------------LRPGVLCAIALNLLAG-----------VRMVEDDY
MUL_2555|M.ulcerans_Agy99 --------------GGASASALLISSFISLYR----------YGDVTATH
MAV_2364|M.avium_104 --------------ADVDDADEWLIARWGCLRAANLAWGCGDAEGATRVL
MLBr_02341|M.leprae_Br4923 -----------KTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQL
Mb0393|M.bovis_AF2122/97 WMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAA
Rv0386|M.tuberculosis_H37Rv WMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAA
Mvan_1214|M.vanbaalenii_PYR-1 RSAAERLET--------------LDGELSRETYLEALAAAMYASARCGDP
MSMEG_0321|M.smegmatis_MC2_155 LDAARRLES--------------LDDELALQTHLEAIAAAMYAG-HLGAP
TH_3225|M.thermoresistible__bu LTAAQLLQD--------------VDAPAARESYLEAFAALMYAG-RLAPS
MAB_3361|M.abscessus_ATCC_1997 VEAARCLEN--------------LDDNLARETYLDAVGAAMYGG-RLCPR
MMAR_0085|M.marinum_M LAAAQRMQR--------------LDPSESRKAYLGAVLASILVGRMATDQ
Mflv_1156|M.gilvum_PYR-GCK IRAVELLER----------------ARADADNDAVLVTTLLSLGFCLGMT
MUL_2555|M.ulcerans_Agy99 RRLVERLQS-----------------------------ADDLDGETLTRM
MAV_2364|M.avium_104 AEVKQRLAT--------------------------EGSLQLIDALDVSIG
MLBr_02341|M.leprae_Br4923 VRAVAQISG----------------------LDDRSARARVREQIPDADT
:
Mb0393|M.bovis_AF2122/97 AGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAI
Rv0386|M.tuberculosis_H37Rv AGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAI
Mvan_1214|M.vanbaalenii_PYR-1 GLLMSTAEGARRAVSRLDTLDHPADHLLSGLATLLVGGRREGADHLRTAL
MSMEG_0321|M.smegmatis_MC2_155 DALLTTAAAAQAAVDRLASRDDPIALLLDGVAKCLTGDVGDAAVPLRKAL
TH_3225|M.thermoresistible__bu GALLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVAL
MAB_3361|M.abscessus_ATCC_1997 GGAVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEAL
MMAR_0085|M.marinum_M HNSSPSVAKAASNAPAAPHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAI
Mflv_1156|M.gilvum_PYR-GCK GSFTAQLATVREAVAVAERAGVPA-LTSRALAMWVHVSFQAGNGLDSAAL
MUL_2555|M.ulcerans_Agy99 VNLLLAVSMFAADPALWQITDGLVDSLADRLGELSVIYRDAWADAARRGR
MAV_2364|M.avium_104 FFRGDIARTIELGPRLCEPDVVPMATVWAAVATCGALTAVGRFSEVGRIA
MLBr_02341|M.leprae_Br4923 QDLLLLDDLLGIADPAVELPRLDPDARRRRLTALINVAQLALSRPAVFVV
:
Mb0393|M.bovis_AF2122/97 DLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHS
Rv0386|M.tuberculosis_H37Rv DLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHS
Mvan_1214|M.vanbaalenii_PYR-1 RMWCARAGERDGQDLRWLSLAFPIVHECCAAELYDDGLTHELADVMVRYA
MSMEG_0321|M.smegmatis_MC2_155 TAWCSAAQHGDGAVLPWIFVGYPIVQESAVDELWDDTLMERLADAMVRYT
TH_3225|M.thermoresistible__bu TAMCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQA
MAB_3361|M.abscessus_ATCC_1997 TLIRCEADR--PANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIA
MMAR_0085|M.marinum_M REYLR------ERDIGVAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDL
Mflv_1156|M.gilvum_PYR-GCK LRAVDLEDPEDNTPIPFRASAARGLSLALTGRLAEADG---QLAAVAQRS
MUL_2555|M.ulcerans_Agy99 TVTQRLKEQLDRLAELEPWDVMRVALAGYYVDLIDDFR--SVLVPLADRE
MAV_2364|M.avium_104 AAGVRATAQCRAGAQRFAIGLAEVMAATAAGDYPAAERIHKRYAALAT--
MLBr_02341|M.leprae_Br4923 EDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIA
Mb0393|M.bovis_AF2122/97 NALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLA
Rv0386|M.tuberculosis_H37Rv NALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLA
Mvan_1214|M.vanbaalenii_PYR-1 RDVGALAVLPAALSYRAGIHVIAGEFNTAATLLDESDAISAAINYR-PVK
MSMEG_0321|M.smegmatis_MC2_155 RDAGALAILPAALSCRAGAHLLSGEFGTAGNLLDEANAIAVAIADQ-PLR
TH_3225|M.thermoresistible__bu RDAGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVR
MAB_3361|M.abscessus_ATCC_1997 REVGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGHA-PIR
MMAR_0085|M.marinum_M RAAGALTMLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATGAP-PRP
Mflv_1156|M.gilvum_PYR-GCK AQRGAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMVIA
MUL_2555|M.ulcerans_Agy99 IEGGAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGY
MAV_2364|M.avium_104 ---GLPAAEAMVDAMLGVLQLTRGELQEACATLDRSISQLSQGFPLPWQL
MLBr_02341|M.leprae_Br4923 VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR--EL
.
Mb0393|M.bovis_AF2122/97 FAL---AYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDV
Rv0386|M.tuberculosis_H37Rv FAL---AYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDV
Mvan_1214|M.vanbaalenii_PYR-1 YHR---LHLAAWRGVPADALALIEPATKEATAKGEGR-------------
MSMEG_0321|M.smegmatis_MC2_155 YHR---LHLAAWRGSTAETIAMIDSATAMAHRNGEGR-------------
TH_3225|M.thermoresistible__bu YHR---LIIAAWRGDAVEAARLIEAAAADGEARGEGR-------------
MAB_3361|M.abscessus_ATCC_1997 YHS---LILAAWRGSEPTAIRLIDEAMRDGAARGEGR-------------
MMAR_0085|M.marinum_M AIK---TYLAAYRGQEQICREGVQQTVDSAASRGEGY-------------
Mflv_1156|M.gilvum_PYR-GCK FSIC--AAVAAYRGREDQARDQAAGALAQGGDYVALT-------------
MUL_2555|M.ulcerans_Agy99 QLRGYLGVISACRGDVVRARELAAQVRVWAEPRRVGF-------------
MAV_2364|M.avium_104 VVGALQAQAEGARGDSAAAAVALRRVEEAYGPHVAVF-------------
MLBr_02341|M.leprae_Br4923 AER---GVLTGERGRYACSTDVAEVCVPATLQATIAAR------------
.
Mb0393|M.bovis_AF2122/97 QTAQHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAV
Rv0386|M.tuberculosis_H37Rv QTAQHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAV
Mvan_1214|M.vanbaalenii_PYR-1 ----------------LLGLAGYASALLYNGLGRYQEAFQAARRTCEEVD
MSMEG_0321|M.smegmatis_MC2_155 ----------------LLAVLGYFAALLYNGAGRYEEAYAAIRPACSTKN
TH_3225|M.thermoresistible__bu ----------------LMGLTGYAAALLYNGIGRYREALAAARTTCEYED
MAB_3361|M.abscessus_ATCC_1997 ----------------LLGAMGYAAGVLNNSLGRYELAFMAARRACEHED
MMAR_0085|M.marinum_M ----------------DVSVAMYAAAILHNGLGQYQEAFNAAASGARYDD
Mflv_1156|M.gilvum_PYR-GCK ------------------VWASATLAFLEVSRGNYEQALEAAEPLVDLYR
MUL_2555|M.ulcerans_Agy99 ----------------LTGAVAQIAILCSFAEGDYESAYLQATAITAPGE
MAV_2364|M.avium_104 -----------------LPELELARAWERAAAGDTAGAQTQAMQAAQTAR
MLBr_02341|M.leprae_Br4923 -----------------IDRLSPPAKQLLVAAAVIGFRFGSDLLASLGID
.
Mb0393|M.bovis_AF2122/97 QS-----MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAH
Rv0386|M.tuberculosis_H37Rv QS-----MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAH
Mvan_1214|M.vanbaalenii_PYR-1 LG-----FHGWCLVELIESAARIDELDEAASALHRLEERAADTGTEWGLG
MSMEG_0321|M.smegmatis_MC2_155 LG-----FGGWSLVELIEAAVHTGRREAAEEAADRLAAQAGASGTDWGLG
TH_3225|M.thermoresistible__bu LG-----FYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWGLG
MAB_3361|M.abscessus_ATCC_1997 LG-----LYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQG
MMAR_0085|M.marinum_M VG-----MCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALG
Mflv_1156|M.gilvum_PYR-GCK DFPGTELMSACFMPDAIESLIAVGRLDEAEPLIAAFERNGAELDRPWQLA
MUL_2555|M.ulcerans_Agy99 FPP-LALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRLAI
MAV_2364|M.avium_104 KAG---------MHLVEMRARHAALRFGDRAQAARVDELASILNSPSAQA
MLBr_02341|M.leprae_Br4923 LS------VDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRA
:
Mb0393|M.bovis_AF2122/97 LDLPDVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYR
Rv0386|M.tuberculosis_H37Rv LDLPDVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYR
Mvan_1214|M.vanbaalenii_PYR-1 ALAGAKALLADDE----YADALFTEAIARLDQTRVAVHAARTRLCYGEWL
MSMEG_0321|M.smegmatis_MC2_155 ALAGARAMLADHD----TADALFTEAIERLQRTRIAVELARTHLRYGEWL
TH_3225|M.thermoresistible__bu ALAGARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLTYGEWL
MAB_3361|M.abscessus_ATCC_1997 MVARSRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGEWL
MMAR_0085|M.marinum_M IGASATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLTYGEWL
Mflv_1156|M.gilvum_PYR-GCK IGNRCRAMLLSATGDLDGALAAAERAMAEHARLPMPFERARSALTLGEVL
MUL_2555|M.ulcerans_Agy99 ATGAAEALCASDE----RAPALFEKVLGHPAVASFPFEHARIRLAYGMRL
MAV_2364|M.avium_104 VAGHARGLAQHDG------DLLDAAAHRFADLGALAFAADAAAQAASEHA
MLBr_02341|M.leprae_Br4923 RLHRRLAAAIEAR-------APHSVDQHAVLIAEHLEAAGDLHAAYGWHM
.
Mb0393|M.bovis_AF2122/97 SDYVQSVTALRDAMGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRPAT
Rv0386|M.tuberculosis_H37Rv SDYVQSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPAT
Mvan_1214|M.vanbaalenii_PYR-1 RRRNR-RPDARTQLGDAHEMFTRFGAQAYAERARRELTAAGEKVRTQPDG
MSMEG_0321|M.smegmatis_MC2_155 RRVNR-RPDARRHLGVAFDMFTRMGAAGFAERARRELTATGEKVRKQPVS
TH_3225|M.thermoresistible__bu RREHR-RGEARRELNEAHGMFTRMGAQGFAERSRRELIAVGEKVRRQPLT
MAB_3361|M.abscessus_ATCC_1997 RRCNR-RSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRKRSAS
MMAR_0085|M.marinum_M RRERR-RSEARSQLRIAYDMFAQMGAAGFAERARRELSATGEAVYVQPTG
Mflv_1156|M.gilvum_PYR-GCK RRLRR--RDAAAAVRDALAQFEELGVPLWVARARIALSGLAVSG----SA
MUL_2555|M.ulcerans_Agy99 RRLRR-YRNARVVLRAAAEIFAGLGAEPWTQRARNELRAAGTAVRHSAAV
MAV_2364|M.avium_104 RRGDRRKEVESSTWAHALAGQCGSRTPALDAAAR----------------
MLBr_02341|M.leprae_Br4923 RAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCIAPRTRLCGIA
Mb0393|M.bovis_AF2122/97 GWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFT
Rv0386|M.tuberculosis_H37Rv GWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFT
Mvan_1214|M.vanbaalenii_PYR-1 TGGELTAQETQIARLAAEGFTNQEIGAQLFISAHTAEWHLRKVFVKLGIT
MSMEG_0321|M.smegmatis_MC2_155 SGDELTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWHLRKVFVKLGIG
TH_3225|M.thermoresistible__bu SGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGIT
MAB_3361|M.abscessus_ATCC_1997 SEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGIT
MMAR_0085|M.marinum_M ITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVT
Mflv_1156|M.gilvum_PYR-GCK VGSELTDSERRIAELAASGMSNRDVAETLFVSVKTIETNLSRVYRKLGIR
MUL_2555|M.ulcerans_Agy99 GPAPLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLGVT
MAV_2364|M.avium_104 -PLPFSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTKLGIN
MLBr_02341|M.leprae_Br4923 WRGRFNSS----SGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDRLH-
:. : . :: * : ::: .
Mb0393|M.bovis_AF2122/97 SRLQLAQAAARRT------
Rv0386|M.tuberculosis_H37Rv SRLQLAQAAARRT------
Mvan_1214|M.vanbaalenii_PYR-1 SRRQLRSISWAS-------
MSMEG_0321|M.smegmatis_MC2_155 SRRQLRTIEWAG-------
TH_3225|M.thermoresistible__bu SRRQLRAAPRVTATW----
MAB_3361|M.abscessus_ATCC_1997 SRRQLRSGR----------
MMAR_0085|M.marinum_M SRRELRAILMESP------
Mflv_1156|M.gilvum_PYR-GCK SRAQLGRMLR---------
MUL_2555|M.ulcerans_Agy99 NRAGLHDALDAIHAAPDQI
MAV_2364|M.avium_104 NRDQLIQLIRRDAS-----
MLBr_02341|M.leprae_Br4923 -------------------