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TTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVS RAAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGL NSGQVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQTVRIKGAEDAV PARRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKG LEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADPAV ELPRLDPDARRRRLTALINVAQLALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYH GALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITRELAERGVLTGE RGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGSDLLASLGIDLSVDELIDANL VDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVDQHAVLIAEHLEAAGDLHA AYGWHMRAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNSSSGFDEV RQLCNATGDKAPLAVATVGPAIDHVYQDRLH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02341 | - | - | 100% (732) | putative regulatory protein |
| M. leprae Br4923 | MLBr_00201 | - | 1e-13 | 28.71% (202) | hypothetical protein MLBr_00201 |
| M. leprae Br4923 | MLBr_01399 | - | 1e-08 | 29.03% (155) | hypothetical protein MLBr_01399 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1651c | cya | 1e-14 | 29.24% (171) | membrane-anchored adenylyl cyclase Cya (ATP |
| M. gilvum PYR-GCK | Mflv_4653 | - | 1e-20 | 25.55% (634) | transcriptional regulator |
| M. tuberculosis H37Rv | Rv1625c | cya | 1e-14 | 29.24% (171) | membrane-anchored adenylyl cyclase Cya (ATP |
| M. abscessus ATCC 19977 | MAB_0490c | - | 2e-15 | 31.11% (180) | putative adenylate cyclase |
| M. marinum M | MMAR_5257 | - | 0.0 | 68.76% (733) | membrane-anchored adenylyl cyclase |
| M. avium 104 | MAV_3162 | - | 9e-14 | 29.24% (171) | adenylate cyclase |
| M. smegmatis MC2 155 | MSMEG_0228 | - | 0.0 | 60.95% (717) | adenylate and guanylate cyclase catalytic domain-containing |
| M. thermoresistible (build 8) | TH_3225 | - | 3e-16 | 25.89% (479) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_3594 | - | 7e-20 | 27.40% (292) | adenylylate/guanylate cyclase |
| M. vanbaalenii PYR-1 | Mvan_1904 | - | 1e-159 | 46.97% (692) | adenylyl cyclase class-3/4/guanylyl cyclase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02341|M.leprae_Br4923 -----MTTALVCVACGAELRSIAKFCDECGSPVVEAETP-AEYKQVTVLF
MMAR_5257|M.marinum_M -----MTPVLACRSCGTQPLENARFCHGCGAPVAAAADAHAEYKQVTVLF
MSMEG_0228|M.smegmatis_MC2_155 --------MVACGTCGTELRQGARFCDSCGTAIVDGSKH-AEYKQVTVLF
Mvan_1904|M.vanbaalenii_PYR-1 ---------------------------------------------MTVLF
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv -------------------------------------------------M
MAV_3162|M.avium_104 -------------------------------------------------M
Mflv_4653|M.gilvum_PYR-GCK MRYRLLGPLQVVHGEAAVDIGPRKQRSVLAALLLAQGRVVSTDRLVDVVW
MAB_0490c|M.abscessus_ATCC_199 ----------------------MTGAEGRPDRRPLARAARYSRWVMRTPW
MUL_3594|M.ulcerans_Agy99 ------------------------------------------------MH
TH_3225|M.thermoresistible__bu -------------------------MSSRDGDVVLHGRAAEIATLRDVMS
MLBr_02341|M.leprae_Br4923 ADVVGS--------------MDIAAAVGLERLREIMTELVSR--------
MMAR_5257|M.marinum_M ADVVHS--------------MDIAAALGAERLREIMTELVNR--------
MSMEG_0228|M.smegmatis_MC2_155 ADVVDS--------------MRLAAAVGAERLREILSALVSR--------
Mvan_1904|M.vanbaalenii_PYR-1 ADVVGS--------------MRLAAELDPERLREIMNDLFNR--------
Mb1651c|M.bovis_AF2122/97 --------------------------------------MRTQ--------
Rv1625c|M.tuberculosis_H37Rv AARKCG--------------APPIAADGSTRRPDCVTAVRTQ--------
MAV_3162|M.avium_104 AAKSCG--------------AAPLWPTGSSKRPDCVAAARAQ--------
Mflv_4653|M.gilvum_PYR-GCK GDDVPASATASLQVYISNLRRALRSGAGDRTVSSVAQPIVRQPPGYFLDA
MAB_0490c|M.abscessus_ATCC_199 PLFIMG--------------IAQSNLVGALFVLGFLRFGLPPS-------
MUL_3594|M.ulcerans_Agy99 VNGFGG--------------LAAQQVAASPICCAPLDERSAIPG------
TH_3225|M.thermoresistible__bu TARAGSS------------RVLVLHGEAGVGKTALLGQLLGDAAG-----
MLBr_02341|M.leprae_Br4923 --AAGVIERYGGTVDKFTGDGIMAIFGAPTALEDHALRACLAALGVQE-K
MMAR_5257|M.marinum_M --AAVVVQRYGGTVDKFTGDGIMAVFGAPAALEDHALRACLAALGVQD-E
MSMEG_0228|M.smegmatis_MC2_155 --CSGVVGHYGGTVDKFTGDGIMALFGAPLALEDHALRACLAALDLQY-E
Mvan_1904|M.vanbaalenii_PYR-1 --SATVVQRYHGTMDKFTGDGLMALFGAPMALEDHALRACIAALEIQA-V
Mb1651c|M.bovis_AF2122/97 --ARAPTQHYAESVARRQRVLTITAWLAVVVTGSFALMQLATG------A
Rv1625c|M.tuberculosis_H37Rv --ARAPTQHYAESVARRQRVLTITAWLAVVVTGSFALMQLATG------A
MAV_3162|M.avium_104 --SRARNQHYADSAARQSRVLAIAAWLAVLVCADFILLQVVTG------A
Mflv_4653|M.gilvum_PYR-GCK GPDESDIAVFTAACARAAAAIDGERWDEALAEADTALSLVRGELLEDIGD
MAB_0490c|M.abscessus_ATCC_199 --DRVELTELGPTRLIILGFSLFILFVVGAIVSTYLLLPVLRWQYRSPDF
MUL_3594|M.ulcerans_Agy99 --PQPPVRLLVVDDADGVETLFGARFRTELRCDEYDLSFSNDPVQALKMV
TH_3225|M.thermoresistible__bu --MRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSPQRDVLNVAFGR
MLBr_02341|M.leprae_Br4923 ARRLAAEVGDRDGVDLQLRVGLNSGQVIVGEIGSSALGYTAVGVQVGMAQ
MMAR_5257|M.marinum_M AKRLAGEVDRRDGVVLQLRVGLNSGQVVAGEIGTGALGYTAVGEQVGLAQ
MSMEG_0228|M.smegmatis_MC2_155 SHRLADELDLPAGVGLQIRVGLNSGQVIAGEMSAGGFGYTAIGEQVGMAQ
Mvan_1904|M.vanbaalenii_PYR-1 VGELADEVEQRDGVRLQLRVGLNSGDVVVGDIGSGPGRYTAIGHAVGMAQ
Mb1651c|M.bovis_AF2122/97 GGWYIALINVFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIG----
Rv1625c|M.tuberculosis_H37Rv GGWYIALINVFTAVTFAIVPLLHRFGGLVAPLTFIGTAYVAIFAIG----
MAV_3162|M.avium_104 WTWQIVSLNVVAALIFAIVPWLHRFGDLVAPLTFLGAAYVTVFVSC----
Mflv_4653|M.gilvum_PYR-GCK ADWIREDAARFAEMRTECLAGKVMSLLALGKIPAALTAASQLGALDPLAD
MAB_0490c|M.abscessus_ATCC_199 ESEGSEAVRVRALQMPFYRTVISVATWLVGGAIFVAVTWSST--------
MUL_3594|M.ulcerans_Agy99 GDSPDIEVLVTNLNMPQMNGLDLLTEVAKLGRPLKTIVLTACNDLAN---
TH_3225|M.thermoresistible__bu GAGPAPGRFLVGLAVLNLLAAAGADQPLLCVIDDAQWLDRVSLQTLGFVA
MLBr_02341|M.leprae_Br4923 R------------------------------MESVAPPGVVMLSESTARL
MMAR_5257|M.marinum_M R------------------------------MEAVAAPETVMLGESTARL
MSMEG_0228|M.smegmatis_MC2_155 R------------------------------MESVAPHGGIMCSDTTARL
Mvan_1904|M.vanbaalenii_PYR-1 R------------------------------MEAAASAGAVVCSLSTADL
Mb1651c|M.bovis_AF2122/97 ------------------------------------------WDVGTDAG
Rv1625c|M.tuberculosis_H37Rv ------------------------------------------WDVGTDAG
MAV_3162|M.avium_104 ------------------------------------------WDVGTASG
Mflv_4653|M.gilvum_PYR-GCK RGCRLQMLALYRAGRTADALEVYTRYARRLDAELGLEPGPELRDLQTAVL
MAB_0490c|M.abscessus_ATCC_199 ---------------------------------------------HSSVL
MUL_3594|M.ulcerans_Agy99 --------------------------------------------IRAAMM
TH_3225|M.thermoresistible__bu R-----------------------------------RLMAEPVAMVFALR
MLBr_02341|M.leprae_Br4923 VEQTAVLGAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWE
MMAR_5257|M.marinum_M VEGAAVLGEPQLVHIKGVEAAVPAWQLLGVVDQYWQSGPAPATLVGREWE
MSMEG_0228|M.smegmatis_MC2_155 VEDSVLLGAPEMLRVKGCDRPVAARRLLAATNAAHG-GRSDPTLVGRSWE
Mvan_1904|M.vanbaalenii_PYR-1 VEHATRLGAVQTVRIKGSDEPAPARRLVAVEAARMVVGRNEGLMLGRDGE
Mb1651c|M.bovis_AF2122/97 AQFFFLVAAALVVLLVGIEHTALAVGLAAVA---------AGLVIALEFL
Rv1625c|M.tuberculosis_H37Rv AQFFFLVAAALVVLLVGIEHTALAVGLAAVA---------AGLVIALEFL
MAV_3162|M.avium_104 GQYFFLVGACLVLLVMGIEHTVLAAVLAAIG---------AGLVIAVEFA
Mflv_4653|M.gilvum_PYR-GCK RQAPELSGWPRSPGWTG-AAAVTATEAVPVRLDTVESASHRAPLVGRRRE
MAB_0490c|M.abscessus_ATCC_199 VAAFATVLGATTTSIIGYLQSERVLRPVAIQALR------RGVPENVTAP
MUL_3594|M.ulcerans_Agy99 RGAFDFQLTPLDLEDLRVTISKAVTIVRELQAG----EAARQRALELADQ
TH_3225|M.thermoresistible__bu DDIHEALVGVPALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRGN
.
MLBr_02341|M.leprae_Br4923 LATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSV
MMAR_5257|M.marinum_M LDTLTTMLDRSIAGRGSVVTLVGRAGIGKTRLAREAAQVAKNLGVTVFST
MSMEG_0228|M.smegmatis_MC2_155 LNTIAGLLDEAVEGRGGIVSVVGPPGIGKSRMVRESIELARRRGVAVFYT
Mvan_1904|M.vanbaalenii_PYR-1 LHQLCDSLDRRR--RRHLVSVVGAPGVGKSRLVEEFCRRLRGAGTEVVLA
Mb1651c|M.bovis_AF2122/97 VPPDTGLQPPWAMSVSFVLTTVSACGVAVATVWFALRDTAR---------
Rv1625c|M.tuberculosis_H37Rv VPPDTGLQPPWAMSVSFVLTTVSACGVAVATVWFALRDTAR---------
MAV_3162|M.avium_104 FPRDTGLQPAWAQSMSFVVTIVSACIMVFVAVWFALRDTQR---------
Mflv_4653|M.gilvum_PYR-GCK LAAAADVLDRVTAGAARWLVLSGPPGIGKTRLAEEIAGLVAAGDGDVVWV
MAB_0490c|M.abscessus_ATCC_199 GVIVRQILTWALSTGVPILAIVLTVVGQRAGYLKSNADNLTG--------
MUL_3594|M.ulcerans_Agy99 NRRVENIFGRYVSEEVKTHLLACPEGHQNSERRTLTMLMADIRG------
TH_3225|M.thermoresistible__bu PLALLEVPRTYAVGELAGGFVSPGAGSAPSRIEENYVHRIRALP------
MLBr_02341|M.leprae_Br4923 FCESHATDVAFDVVAQLVRAVAQIS--------GLDDRSARARVREQIPD
MMAR_5257|M.marinum_M FCESHATDIPFRAVTRLLRAAAQVS--------RLDDATARVRVRAIVPD
MSMEG_0228|M.smegmatis_MC2_155 YCESHASDVPFHVVVPLLREGFGVA--------GLDPAAARVRVRSLVPD
Mvan_1904|M.vanbaalenii_PYR-1 GCDAHAMPIAFRALSRLLRAMFSAD--------DLGDDDARELVLSQVPM
Mb1651c|M.bovis_AF2122/97 --AEAVMEAEHDRSEALLANMLPAS--------IAER--LKEPERNIIAD
Rv1625c|M.tuberculosis_H37Rv --AEAVMEAEHDRSEALLANMLPAS--------IAER--LKEPERNIIAD
MAV_3162|M.avium_104 --AEAVMESEYQRSEALLANMLPGS--------IAER--LKHSDGDIIAD
Mflv_4653|M.gilvum_PYR-GCK NCPDERGTPPWWPMRQLVRALGADADEVLEIPPHADPDTARFLVYERIQR
MAB_0490c|M.abscessus_ATCC_199 ---SILILAIIALAIGLMGTLLVATS-------IADPLRQLRWALSEVQR
MUL_3594|M.ulcerans_Agy99 -FTRLSEILSPERALQVLNAYLERAT------------DVVIRWNGTINE
TH_3225|M.thermoresistible__bu --AQTRRLLLIAAAEPIGDSALFLR-----------AAALMGIAVDALAP
: :
MLBr_02341|M.leprae_Br4923 ADTQDLLLLDDLLGIADPAVELPRLDPDARR--RRLTALINVAQLALSRP
MMAR_5257|M.marinum_M GDPQDLLLLYDLLGIADPQVELPKIAPEARR--RRLTALINAVQLARAQP
MSMEG_0228|M.smegmatis_MC2_155 ADPEDLLLLDDVLGIADPDVPMPDLDADARR--RRVAALVNAASLARREP
Mvan_1904|M.vanbaalenii_PYR-1 G-STDAQIIFEAMGIADGAAPPLHVGADGRR--HRLVETMAQFVRLRSTP
Mb1651c|M.bovis_AF2122/97 KYDEASVLFADIVGFTERASSTAPADLVRFL--DRLYSAFDELVDQHGLE
Rv1625c|M.tuberculosis_H37Rv KYDEASVLFADIVGFTERASSTAPADLVRFL--DRLYSAFDELVDQHGLE
MAV_3162|M.avium_104 KYDDASVLFADIVGFTERASGTAPADLVRFL--NRLYIAFDELVDKHGLE
Mflv_4653|M.gilvum_PYR-GCK LLESAPRLLAVVVDDVQWADTTSAACLAYIAGTLRDRPVLVVVTVRDGEH
MAB_0490c|M.abscessus_ATCC_199 GNYNAHVPIYDASELGLLQAGFNDMVRDLGE-RQRLRDLFGRYVGEDVAR
MUL_3594|M.ulcerans_Agy99 ILGDGLLVFFGVPNTDGEAAEHAVAAALELQ------LAMGELNVSHREQ
TH_3225|M.thermoresistible__bu AEAARVIQFGPRMRFFHPLMRSAAYRAADPRDRRAVHRALAEATDPGADP
: .
MLBr_02341|M.leprae_Br4923 AVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVG
MMAR_5257|M.marinum_M AVYVIEDAHWMDEASESMVAEFLTVIPQTHSMVLVTYRPDYRGALRGVRG
MSMEG_0228|M.smegmatis_MC2_155 GLYVLEDAHWIDEVSESMLAEFLTVVTHTHSVMLITYRPEYTGVLARVSG
Mvan_1904|M.vanbaalenii_PYR-1 MVLVLEDAHWIDAASEAVLCEFATVLERTSTVLVTTCRPEYRGGLRKRS-
Mb1651c|M.bovis_AF2122/97 KIKVSGDSYMVVSG-------------------VPRPRPDHTQALADFAL
Rv1625c|M.tuberculosis_H37Rv KIKVSGDSYMVVSG-------------------VPRPRPDHTQALADFAL
MAV_3162|M.avium_104 KIKVSGDSYMVVSG-------------------VPRVRPDHATALADFAL
Mflv_4653|M.gilvum_PYR-GCK PAEVSRLLSTVARGEANRLIEVPALSSEDVATLANEVAEEVVTAAEAAEL
MAB_0490c|M.abscessus_ATCC_199 RALEYGTELGGQERS------------------VAVLFVDLVGSTQLAST
MUL_3594|M.ulcerans_Agy99 GLPELGIGIGVHTG----------------EAVVGTIGSPRRQKYTAIGK
TH_3225|M.thermoresistible__bu DRRAWHAANGVTGTD-------------------DAVAAELEKSAARAQQ
MLBr_02341|M.leprae_Br4923 AQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEIT
MMAR_5257|M.marinum_M AQSIALGPLSDAETSALIAELLGPAPSVAQIAEIIATRAAGNPFFAEEII
MSMEG_0228|M.smegmatis_MC2_155 AQTIALRPLTDGQTSTLLTELLGPDAAAHQLAGLIADRAAGNPFFTQEIV
Mvan_1904|M.vanbaalenii_PYR-1 AHTVTVAPLNDSLTMDLVLNLLGGDGAMGGLASRIVGVAAGNPYFVEEIV
Mb1651c|M.bovis_AF2122/97 DMTNVAAQLKDPRGNPVPLRVG----------------------------
Rv1625c|M.tuberculosis_H37Rv DMTNVAAQLKDPRGNPVPLRVG----------------------------
MAV_3162|M.avium_104 DMVKVAAALKDPYGRPVPLRVG----------------------------
Mflv_4653|M.gilvum_PYR-GCK ADRTGGNPFFVSEYARLPREERAGNEIPRAVRSVLDRR---LAALDPAVM
MAB_0490c|M.abscessus_ATCC_199 RGPAVVVRVLNEFFRVIVDTVN----------------------------
MUL_3594|M.ulcerans_Agy99 NVNLVARIESNTVGGQVLVSES----------------------------
TH_3225|M.thermoresistible__bu RGGIAATATFLERAVVLTADPG----------------------------
:
MLBr_02341|M.leprae_Br4923 RELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQLL
MMAR_5257|M.marinum_M RELAERRVLVGERGRYTCTAEADDAIVPATLQATIGARIDRLSPAAKQTL
MSMEG_0228|M.smegmatis_MC2_155 RDLAERGVLRGERGAYRFHGADVEIGVPATLQATIAARIDRLEVEAKRTL
Mvan_1904|M.vanbaalenii_PYR-1 RDLVGRGVLAGSRGDYRLIRDVDDIGVPVTVQAVLAARIDRLAPATKAVL
Mb1651c|M.bovis_AF2122/97 --LATGPVVAGVVGSRRFFYDVWGDAVNVAS-------------------
Rv1625c|M.tuberculosis_H37Rv --LATGPVVAGVVGSRRFFYDVWGDAVNVAS-------------------
MAV_3162|M.avium_104 --MACGPVVAGVVGSRRFFYDVWGDAVNVAS-------------------
Mflv_4653|M.gilvum_PYR-GCK QVLRAAAVIADVLDSVTVPLLARTTALDLDTLADYLDEAADERIIVNSHT
MAB_0490c|M.abscessus_ATCC_199 ---KHGGFVNKFQGDAALAIFGAPIDHPDGAAAALAAARELSG-------
MUL_3594|M.ulcerans_Agy99 -TYHEICAIADTSGSTQVRVKGLTEPITVHDITGLAGRYNLR--------
TH_3225|M.thermoresistible__bu --LRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWAR-------
:
MLBr_02341|M.leprae_Br4923 VAAAVIGFRFGSDLLASLGIDLS---VDELIDANLVDQVRFTAPVEYAFR
MMAR_5257|M.marinum_M SAAAVIGSRFSTELLIGLGIDPP---IEELISAELVDQVRFTEPAEYVFR
MSMEG_0228|M.smegmatis_MC2_155 SAAAVIGLRFGPDMLAALGADVS---MQALIDAELVDQVMFAPRPEYAFR
Mvan_1904|M.vanbaalenii_PYR-1 NAAAVIGNRFDAETLQVLTPNARSGELAELVATELIDQMEFAPRQRYCFR
Mb1651c|M.bovis_AF2122/97 ----------------------------RMESTDSVGQIQVPDEVYERLK
Rv1625c|M.tuberculosis_H37Rv ----------------------------RMESTDSVGQIQVPDEVYERLK
MAV_3162|M.avium_104 ----------------------------RMESTDSVGRIQVPETMYERLA
Mflv_4653|M.gilvum_PYR-GCK GDGYVFAHGLLREQLLTGMPALRR-QRVHAKVADVLADSALPDAPTWRAQ
MAB_0490c|M.abscessus_ATCC_199 ----------------------------ELTNVLGSNDFGIGVSAGRAIA
MUL_3594|M.ulcerans_Agy99 ----------------------------LPSIDRKVIPLVVPRPTGIAVI
TH_3225|M.thermoresistible__bu ------------------AVHLRAQLEFARSRAGDAGGPPVGQTAAALLT
.
MLBr_02341|M.leprae_Br4923 HPLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVDQHAVLIAEHLEAA
MMAR_5257|M.marinum_M HPLIHTVAYESQLKSARAQMHRRLAAVIEARVPESADQYAALIAEHLEAA
MSMEG_0228|M.smegmatis_MC2_155 HPLIRMVALESQLKSDRAELHRRLAVDIERRAPHAADEHAALIADHYEEA
Mvan_1904|M.vanbaalenii_PYR-1 HPLVRAVAYDSQISANRARAHRLLAGAIETRDPAAKDENAALIATHLEGA
Mb1651c|M.bovis_AF2122/97 DDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGEVRGAEPRTAGV----
Rv1625c|M.tuberculosis_H37Rv DDFVLRERGHINVKGKGVMRTWYLIGRKVAADPGEVRGAEPRTAGV----
MAV_3162|M.avium_104 SEFVLQERGRIEVKGKGVMRTWYLIGRKPAEAPTDLVAEQPHTAHV----
Mflv_4653|M.gilvum_PYR-GCK HLVAAQPLVEPTVVVPACRLAAEQATQQWSSDIAAGWWQAALDAYDRLPA
MAB_0490c|M.abscessus_ATCC_199 GHIGAQARFEYTVIGDPVNEAARLTELAKNEPGNVLASASAVMEARDEEA
MUL_3594|M.ulcerans_Agy99 ENKIIGAAHPAEVVGSGDGAVRVRTGLQVAPFCDLVLDVAGAQVFAKVVD
TH_3225|M.thermoresistible__bu AAQLLQDVDAPAARESYLEAFAALMYAGRLAPSGALLEAADAVQAAFARA
MLBr_02341|M.leprae_Br4923 GDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMC
MMAR_5257|M.marinum_M GESHAAYGWQVRAAAWATNRDIAAAHLSWERARKIADALPVDDPNRAAMR
MSMEG_0228|M.smegmatis_MC2_155 GDLRAAFTWHMRAGTWLTNRDIDAARLSWQRARHVADQLPHDAEDRAAMT
Mvan_1904|M.vanbaalenii_PYR-1 GDFETACRWHLRAADWLRMRDLLAARNQWEIAMRVADGLPGADDAVTALR
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK SERDDADRDALTVELLEAHSRAGRGQLVLDSVTRYLGEALRTGRAASAGR
MAB_0490c|M.abscessus_ATCC_199 LRWDVGETVELRGRTVSTQVARPRHG------------------------
MUL_3594|M.ulcerans_Agy99 CGVDGGICELMAVFTSVSDDVRRALAAPSTANSLS---------------
TH_3225|M.thermoresistible__bu PEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEVVHW
MLBr_02341|M.leprae_Br4923 IAPRTRLCGIAWRGRFNSS--SGFDEVRQLCNATGDKAPLAVATVGPAID
MMAR_5257|M.marinum_M IAPRTMLCGIAFRIHIDVAG-ARFEELRELCAAAGDKASLSIGMAGLVID
MSMEG_0228|M.smegmatis_MC2_155 IAPRTLLCLSTWRAGGHLSD-TGFDELCALAAAADDKVSLATAMAGQVSA
Mvan_1904|M.vanbaalenii_PYR-1 IAPRTMLVSTELFVGADPDNDQRLVELRELTARVDDSHSLALALAGRIVT
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK VASALLRASGGWPWLAPGNDPGELLTLLSRAATLSEGEPASAARVLPALA
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu LVPAFPVLQESAG---HELWDENLVDALSEAVVRQARDAGALAGLPQALV
MLBr_02341|M.leprae_Br4923 HVYQD-RLH-----------------------------------------
MMAR_5257|M.marinum_M HLQHA-RMREASQLATEAMTLIESVGDP--ALTVALSIALIYAKSECAEW
MSMEG_0228|M.smegmatis_MC2_155 LLVHA-HYRESSSLASELTSLLESVGDR--RLTVALLFAALGAKFQTGEA
Mvan_1904|M.vanbaalenii_PYR-1 FIVNSNRVPEALPLAAELAELVDTLGPTPAAELEIIYTAMSFAHLASCEF
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK VGHCYHPDPTIAPELLDRAERLAEATGDPDVIADVLIGRLITFSGVATLS
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu YRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHRLIIAAWRGDAV
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
MMAR_5257|M.marinum_M SDALRWSQRVIALADGDPTMGALIIGCPLAVAFATRANARYCLGRPGWAE
MSMEG_0228|M.smegmatis_MC2_155 NEVVRLADRLIELADGDANMGNLIIGSPLVTAWTVGGMARACLGDPDWRT
Mvan_1904|M.vanbaalenii_PYR-1 DAALEVIGRSIALEPEYP-------STDRALAYAIGGLCEVCLGSRERGI
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK AQSLEWVQRLNALRHSRSREDAVIAHSVATMAAMNLGDVDGARRHVQAGI
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu EAARLIEAAAADGEARGEGRLMGLTGYAAALLYNGIGRYREALAAARTTC
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
MMAR_5257|M.marinum_M D-LQHGLAMARSADPMSYATVVAYVYSAGISTGVLASDDCALGEIEDALQ
MSMEG_0228|M.smegmatis_MC2_155 G-LDRATPLVRDFGITTRALMLTYKCIG-LPTGLLLPSPELLEESCEVLE
Mvan_1904|M.vanbaalenii_PYR-1 GHIRLATELARAMSPVSFSAVS--LYWGILAAMGMHVAEDLVDDMREWLA
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK AGSEELQLPVLRAQLRWMEAVLAVWHGDFAEAGRHHAIAAHVHEQTELYE
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu EYEDLG-----------------------FYSWCLHELVEAAARVGETDT
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
MMAR_5257|M.marinum_M IAERSGDDVALAIAR---MTLGIALVHRREDPMRDRGQAALADVSDMFQR
MSMEG_0228|M.smegmatis_MC2_155 VAQRSADDLALAGAQ---VSRGLLLLWQG-GPYRDEALELLSLGREASVR
Mvan_1904|M.vanbaalenii_PYR-1 RAESFGDRFGIIAAQ---WTYATLLLQAG-SPRRDEAFVLLRRAEVGITT
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK AGSGLLARATLLRERGGPVDPSWTDLNAQQAGGLGMVGVVRTGVLTLLSG
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu AHRALGDIEERAGASGTPWGLGALAGARALLADGDEADRLFREALDHLSR
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
MMAR_5257|M.marinum_M RVYFLADLPFVEVYLAREWARCGDLDGAIAHMRAAVEHLFREGRLLGWST
MSMEG_0228|M.smegmatis_MC2_155 EQFTMAAVPAVDTELARDMAARGDLDGAIELARDVVDTSIDSGEAINMSA
Mvan_1904|M.vanbaalenii_PYR-1 HNLQSFALAITGMQLAREAARNGHRDEAIDSIRHLVTLHTRDAPLLHLG-
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK PKARAEALATLRHWAQHTDRAHIWTTLGHHTLLAHLAVDHDLPDFAEPLL
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu SRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAERS
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
MMAR_5257|M.marinum_M PATGVLVQTLLDRGTEGDLVEAAAAIERLAAAPADDGLAVREILLLR---
MSMEG_0228|M.smegmatis_MC2_155 SVT-VLVQSLIARGDRDDLDHAQRVIDRFAALPTDPGFVLYDVQLMR---
Mvan_1904|M.vanbaalenii_PYR-1 CPAESLCEMLIDRGGTRDLLEVEEVLEQWCSR--SPGTAPMDLWTIR---
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK AQLDPYRDRIAVIGQVGMAGPVALATARLHALRGDKAAALADLALARSIA
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu RRELIAVGEKVRRQPLTSGDELTAQEAQIAGLAADGLTNQEIG-------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
MMAR_5257|M.marinum_M -----LRALLARAHGDDTTYARLRDRYRDTASAMGFAGHIAQAESMP---
MSMEG_0228|M.smegmatis_MC2_155 -----LRALLARARGDEERYRECSDRYRELATAYRYEGHMALAARMA---
Mvan_1904|M.vanbaalenii_PYR-1 -----IRALLASARGERQRYAQLADEYAAACEFTGYRHHWGGPYPVLSDR
Mb1651c|M.bovis_AF2122/97 --------------------------------------------------
Rv1625c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3162|M.avium_104 --------------------------------------------------
Mflv_4653|M.gilvum_PYR-GCK ERSAGVPTLLRCRLLECELTEESPGRSTAASTLAAEAADLGMAAVAEAAS
MAB_0490c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3594|M.ulcerans_Agy99 --------------------------------------------------
TH_3225|M.thermoresistible__bu -----AQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW------
MLBr_02341|M.leprae_Br4923 ---
MMAR_5257|M.marinum_M ---
MSMEG_0228|M.smegmatis_MC2_155 ---
Mvan_1904|M.vanbaalenii_PYR-1 RG-
Mb1651c|M.bovis_AF2122/97 ---
Rv1625c|M.tuberculosis_H37Rv ---
MAV_3162|M.avium_104 ---
Mflv_4653|M.gilvum_PYR-GCK RLL
MAB_0490c|M.abscessus_ATCC_199 ---
MUL_3594|M.ulcerans_Agy99 ---
TH_3225|M.thermoresistible__bu ---