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PALSANLVASIDRHPERITLRCDDLQSVFAELGAGPGDRVAALPGDRTRRRVCGPACELSGGRFRPSARP QSCPGLTEAASPGRSRGPLHLARCAAELTIRRGDACQAIELLRRAGELSDRPRRREQLLASAAFVALQAA QLDEAERLLADAGLGGGASASALLISSFISLYRYGDVTATHRRLVERLQSADDLDGETLTRMVNLLLAVS MFAADPALWQITDGLVDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDRLAELEPWDVMRVALAG YYVDLIDDFRSVLVPLADREIEGGAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGY QLRGYLGVISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITAPG EFPPLALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRLAIATGAAEALCASDERAPALFE KVLGHPAVASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRARNELRAAGTAVR HSAAVGPAPLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAA PDQI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2555 | - | - | 100% (635) | hypothetical protein MUL_2555 |
| M. ulcerans Agy99 | MUL_0351 | narL | 5e-06 | 45.00% (60) | nitrate/nitrite response regulator protein NarL |
| M. ulcerans Agy99 | MUL_2423 | devR | 4e-05 | 36.36% (88) | two component transcriptional regulatory protein DevR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0914c | - | 2e-09 | 28.48% (330) | LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 5e-24 | 32.34% (337) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0890c | - | 3e-09 | 28.48% (330) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01753 | - | 6e-09 | 25.06% (435) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3361 | - | 1e-26 | 27.17% (611) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_1324 | - | 0.0 | 99.63% (540) | hypothetical protein MMAR_1324 |
| M. avium 104 | MAV_2364 | - | 1e-11 | 58.18% (55) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_6828 | - | 2e-31 | 28.98% (559) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 6e-30 | 33.02% (324) | PUTATIVE regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 5e-33 | 28.67% (558) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1324|M.marinum_M --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mvan_5002|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1324|M.marinum_M --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mvan_5002|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1324|M.marinum_M --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mvan_5002|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1324|M.marinum_M --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mvan_5002|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 -----------------------------------------------MPA
MMAR_1324|M.marinum_M ----------------MDLGGCRLIERVDELAALESFVNGG--TADGCLA
TH_3225|M.thermoresistible__bu ---------MSSRD-----GDVVLHGRAAEIATLRDVMSTARAGSSRVLV
Mvan_5002|M.vanbaalenii_PYR-1 -----MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRTGASRSLV
MAB_3361|M.abscessus_ATCC_1997 -------------------------------------------------M
Mb0914c|M.bovis_AF2122/97 --------------------------------------MRALLAQNRLVT
Rv0890c|M.tuberculosis_H37Rv --------------------------------------MRALLAQNRLVT
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
MSMEG_6828|M.smegmatis_MC2_155 -----------------------MVGRSEELAAVTD-VLADISTGGAALV
Mflv_1156|M.gilvum_PYR-GCK ------------------------------MKAVDDFLAGLQQLQPAGLL
MAV_2364|M.avium_104 -------------------------------MEFRRSLAALNNGEFHGVA
MUL_2555|M.ulcerans_Agy99 LSAN-------LVASIDR---HPERITLRC--------------------
MMAR_1324|M.marinum_M LRGDSGVGKSMLVQALSERAAVPGRRVLRCSGVEAEAAFVLAGLSQLVY-
TH_3225|M.thermoresistible__bu LHGEAGVGKTALLGQLLG--DAAGMRCVQVAGVESDMELAYAGLHQLCA-
Mvan_5002|M.vanbaalenii_PYR-1 LRGEAGIGKTALLDHVVA--QAEGFRTTYVAGVESDMELAFAGLHQLCA-
MAB_3361|M.abscessus_ATCC_1997 LRGQAGVGKTALLRYVLG--KASGQLIAQASGIQSEMELAFAGLQQFCA-
Mb0914c|M.bovis_AF2122/97 LCGTGGVGKTRLAIQIAS--------ASELRDGLCFVDLAPITESGIVA-
Rv0890c|M.tuberculosis_H37Rv LCGTGGVGKTRLAIQIAS--------ASELRDGLCFVDLAPITESGIVA-
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVAR------VADEFSGELSYFDLAPDTDHDIFP-
MSMEG_6828|M.smegmatis_MC2_155 IDGDPGIGKSTLLAAASDWAVANGYARLGCSGLQSQMEIGYAGLHELLH-
Mflv_1156|M.gilvum_PYR-GCK IEGEAGIGKTTMLAGVVDAARQAGFRVLSAHGDQSGSGLAHAAIADLFAG
MAV_2364|M.avium_104 LVGDGGVGKSTLARMLAKTVESAGRTVRFALGTQTGWAVPLGAFSRAVS-
: . :
MUL_2555|M.ulcerans_Agy99 -----------DDLQSVFAELG--AGPG----------------------
MMAR_1324|M.marinum_M PLREFIAQLGADDQRTLAAVLG--AVPDRVPTVTALTFALLNLLALASEV
TH_3225|M.thermoresistible__bu PLLDRLDDLPSPQRDVLNVAFG--RGAGPAPGRFLVGLAVLNLLAAAGAD
Mvan_5002|M.vanbaalenii_PYR-1 PLLTHLDELPDPQRDALTVAFG--QGAGATPDRFLVGLAVLSLMAAASTG
MAB_3361|M.abscessus_ATCC_1997 PLTKYSGAIPDPQREALTIAFG--TRSGPPPDRFLIGLAVLSLLAAAAEH
Mb0914c|M.bovis_AF2122/97 ATAARAVGLPDQPGRSTMDSLR--RFIGNRRMLMVLDNCEHLLDACAALV
Rv0890c|M.tuberculosis_H37Rv ATAARAVGLPDQPGRSTMDSLR--RFIGNRRMLMVLDNCEHLLDACAALV
MLBr_01753|M.leprae_Br4923 IT--------------VLDNLR--RCIGDRRMLMVLDNCEYLLDVCANVM
MSMEG_6828|M.smegmatis_MC2_155 PLLAQVDALPPRQRAALMTAFG--LEDGPPPDRMLIGLSVLGLLEEAAGN
Mflv_1156|M.gilvum_PYR-GCK VQTDILDGLPELQRRAADGVLRRGDGTGGPTDERVIAAALLGAVHGSATR
MAV_2364|M.avium_104 ---LGVGHEPAIMLAAAHNTLG--------------------------QD
:
MUL_2555|M.ulcerans_Agy99 -----------------DRVAALPGDRTR---------------------
MMAR_1324|M.marinum_M TPLLVVIDDAHWFDDVSARVIAMAGRRLDGAAVRFLAACRNEVPNALADG
TH_3225|M.thermoresistible__bu QPLLCVIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRDDIHEALVG-
Mvan_5002|M.vanbaalenii_PYR-1 GPLLCVIDDAQWLDQVSVQTLAFVARRLLAEPIAMVFAARDTGAEALSG-
MAB_3361|M.abscessus_ATCC_1997 QPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRDGTDSELAG-
Mb0914c|M.bovis_AF2122/97 VELLGACPELTILAT-SREPIGMAGEITWRVPSMSITDEAVELFADRAS-
Rv0890c|M.tuberculosis_H37Rv VELLGACPELTILAT-SREPIGMAGEITWRVPSMSITDEAVELFADRAS-
MLBr_01753|M.leprae_Br4923 TTLLGACPSLTILAT-SREPIGVAGEVIWRVSMLSPADEAVELFTERAA-
MSMEG_6828|M.smegmatis_MC2_155 RRLFLVIDDAQWLDPSSVDVLNFVARRLSNAPLMMLCSTRTTLDGFSVQF
Mflv_1156|M.gilvum_PYR-GCK TPVLVAVDDVQWLDPSSVAVLAFVARRVKGRVGFVVAERPGVGPGLPAAT
MAV_2364|M.avium_104 KNLVVVVDEAQLLDPLSATLVNQLAAGRSARLIVTIRSGEPVLDAVTALL
MUL_2555|M.ulcerans_Agy99 ------------------------------------------------RR
MMAR_1324|M.marinum_M G-------WPQMVLAPLGPEQAERFLDQLDV------DLPHSARVGVLEQ
TH_3225|M.thermoresistible__bu --------VPALAVPGLADADARTLLEHMFPG-----AIDANVRDRLVAE
Mvan_5002|M.vanbaalenii_PYR-1 --------LPELAVPGLSDGEARDLLDSVVVG-----RLDDRVRDRIIAE
MAB_3361|M.abscessus_ATCC_1997 --------LPELTVHGLRAADAGTLLDSVIPG-----LLDERVRDRIVAE
Mb0914c|M.bovis_AF2122/97 -----------RVQPGFTIANHNAAAVGEICR-----RLDGIPLAIEFAA
Rv0890c|M.tuberculosis_H37Rv -----------RVQPGFTIANHNAAAVGEICR-----RLDGIPLAIEFAA
MLBr_01753|M.leprae_Br4923 -----------LVQPGFSVTDGNRQIVTEICQ-----RLDGMPLAIELAA
MSMEG_6828|M.smegmatis_MC2_155 DG------LPRLTMGPLEPADAAELLALTLRDPERSDRVDEVARQRILEQ
Mflv_1156|M.gilvum_PYR-GCK WLQVGTGALTRLPVAPMSLGALHTMLSSRLGR-----RFSRPQIVRIAEV
MAV_2364|M.avium_104 KER----LLLTVHVDPFTREQTELLAGAVLGG-----PVDTRLVDELFER
MUL_2555|M.ulcerans_Agy99 VCG------------PAC----ELSG----------------------GR
MMAR_1324|M.marinum_M AAGNPLALAEL----SRC----ALENSWAPDAPLPLTQRLVAIFGDRLNK
TH_3225|M.thermoresistible__bu SRGNPLALLEVPRTYAVG----ELAGGFVSPGAGSAPSRIEENYVHRIRA
Mvan_5002|M.vanbaalenii_PYR-1 TRGNPLALLDLPHNHVGT----ELPGSAATPGSRPLARRLEQSYARRIKA
MAB_3361|M.abscessus_ATCC_1997 TQGNPLALLELPRDMTAE----ELAGGFGWPDGGRLAGQIEQTFLRRVQQ
Mb0914c|M.bovis_AF2122/97 ARVRSMSPLEIADG-LDD----CFRLLAGGVRGAVQRQQTLRASIDWSHA
Rv0890c|M.tuberculosis_H37Rv ARVRSMSPLEIADG-LDD----CFRLLAGGVRGAVQRQQTLRASIDWSHA
MLBr_01753|M.leprae_Br4923 ARIRTLSLTEIADG-LDD----RFRLLTGGARTAVRRQQTLRASMDWSYA
MSMEG_6828|M.smegmatis_MC2_155 ANGNPMAVIELTIALIES----GDGAPIFAGEPLPTTRRVERAFLTQLGP
Mflv_1156|M.gilvum_PYR-GCK SGGNPLYALELAR----------VADGAGSRPGQRLPESLSELVRLRVDG
MAV_2364|M.avium_104 SAGNLLLLRGFLTAGVESGALVHTEQGWQLQGPLRGDRELHDALEYRLQS
MUL_2555|M.ulcerans_Agy99 FRPSARPQSCPGLT--EAASPG-------RSR------------GPLHLA
MMAR_1324|M.marinum_M LDESVKAQLLRGAL--DGAATGGVASAPPRTRYVMQGVDAAIEHGVLVVD
TH_3225|M.thermoresistible__bu LPAQTRRLLLIAAA--EPIGDSALFLRAAALMGIAVDALAPAEAARVIQF
Mvan_5002|M.vanbaalenii_PYR-1 LPPQTQLLLLAAAA--EPVGDAAVLIRAAAQLGIAVDMLTPAEAAGVIEL
MAB_3361|M.abscessus_ATCC_1997 LPAHTQTLLLAAAT--DPLGDVTLLARAAQQLGIPMHAIAPAEAADLVEL
Mb0914c|M.bovis_AF2122/97 LLTETEQILFRRLA--PFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVD
Rv0890c|M.tuberculosis_H37Rv LLTETEQILFRRLA--PFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVD
MLBr_01753|M.leprae_Br4923 LLTESERALFRRLS--AISGTFDLKVAYAVGHDDLEEPDQVFDRLTMLID
MSMEG_6828|M.smegmatis_MC2_155 LSDESRLLLLLIATG-NGLLSEIDWAADHLGFSLTEHLGSLEESGLITVA
Mflv_1156|M.gilvum_PYR-GCK LAEDVRDVLLVAASATSPTVDLLAKAVGVTPAAVTGLVEAAEVEGIVVID
MAV_2364|M.avium_104 LSSEEREVVEVLAT--AELLEWEILRDICDADAMASLERRGLIQLVTDGS
: .
MUL_2555|M.ulcerans_Agy99 R-------------------------------------------------
MMAR_1324|M.marinum_M RGELVFRHPLVRAAVIQTSTAGQRRHAYAQLADLYP--DDVVRRAAYLAH
TH_3225|M.thermoresistible__bu GPRMRFFHPLMRSAAYRAADPRDRRAVHRALAEATDPGADPDRRAWHAAN
Mvan_5002|M.vanbaalenii_PYR-1 GTRVRFRHPLVRSAAYQAADLADRRTVHRALAEATDSATDPDRRAWHAAN
MAB_3361|M.abscessus_ATCC_1997 STRVRFRHPLVRSAVYISANPLERRRIHGVLAGATDPGADPDRRAWHRAH
Mb0914c|M.bovis_AF2122/97 KS-LVVADDCQGRTRYRLLETVRRYALEKLGDSGEAD-VHARHRDYYTAL
Rv0890c|M.tuberculosis_H37Rv KS-LVVADDCQGRTRYRLLETVRRYALEKLGDSGEAD-VHARHRDYYTAL
MLBr_01753|M.leprae_Br4923 KS-LVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMAL
MSMEG_6828|M.smegmatis_MC2_155 GGRIQIRHPLIRSTVYGAAALASRAAVHRALAAAAT---DPARAAWHRAE
Mflv_1156|M.gilvum_PYR-GCK GNRIRFTHPVLANGIYAGADPQRRREVHRRLADLKT---DPELRARHLAL
MAV_2364|M.avium_104 HTLVQLNHPMLGEAATRHAGVVRSRQLNG---------------------
MUL_2555|M.ulcerans_Agy99 --------------CAAELTIRRGDACQAIELLRRAGELSDRPRRREQLL
MMAR_1324|M.marinum_M ATVDPDPAVVDTLAAAAELTIRRGDACQAIELLRRAGELSDRPRRREQLL
TH_3225|M.thermoresistible__bu GVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPGLRGRRA
Mvan_5002|M.vanbaalenii_PYR-1 AATGPDDAVAAELEASAARAQARGGVAAAAAFLERAAALTSDPALRGARA
MAB_3361|M.abscessus_ATCC_1997 AAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPAARGRRA
Mb0914c|M.bovis_AF2122/97 AASLNTPADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLASSLQ
Rv0890c|M.tuberculosis_H37Rv AASLNTPADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLASSLQ
MLBr_01753|M.leprae_Br4923 GALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQ
MSMEG_6828|M.smegmatis_MC2_155 AAFGPNEEVAADLERVADRARVRGAGAEAAAALRRAAALTDDPQERLRRM
Mflv_1156|M.gilvum_PYR-GCK ASTVADETTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVSR---R
MAV_2364|M.avium_104 -----------ILAKTLRKHLRAAGRRSQISDPRGRIQLAQFIMRSDLEP
. :
MUL_2555|M.ulcerans_Agy99 ASAAFVALQAAQLDEAERLLADAGLG-----GGASASALLISSFISLYRY
MMAR_1324|M.marinum_M ASAAFVALQAAQLDEAERLLADAGLG-----GGASASALLISSFISLYRY
TH_3225|M.thermoresistible__bu LAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLRAQLEFARSRA
Mvan_5002|M.vanbaalenii_PYR-1 LAAAQAKRDAAAPAEAQELLSTAELGRLSELQQAQAARLRAQMEFTRRRG
MAB_3361|M.abscessus_ATCC_1997 LAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAESRV
Mb0914c|M.bovis_AF2122/97 PIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLA
Rv0890c|M.tuberculosis_H37Rv PIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLA
MLBr_01753|M.leprae_Br4923 PIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAILA
MSMEG_6828|M.smegmatis_MC2_155 TVAAEVARSSGLIAESVRILREAEPLIREHESETPLAITRFVLNATAATP
Mflv_1156|M.gilvum_PYR-GCK IRAAEHHVVAGDMRRAATLLEQALVDLRPGVLCAIALNLLAGVRMVEDDY
MAV_2364|M.avium_104 DLDVVIKAAADAMAMSNVVLGEQLATFAVDRGGGLAAALVLAEAVSWQGR
::
MUL_2555|M.ulcerans_Agy99 G-----DVTATHRRLVERLQSADDLDGETLTRMVNLLLAVSMFAADPALW
MMAR_1324|M.marinum_M G-----DVTATHRRLVERLQSADDLDGETLTRMVNLLLAVSMFAADPALW
TH_3225|M.thermoresistible__bu GDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAPS
Mvan_5002|M.vanbaalenii_PYR-1 GDTGARPLDETASQLLTAAASFEQLDGYVSREAYLEALAAAMFAGRLGDP
MAB_3361|M.abscessus_ATCC_1997 GAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPR
Mb0914c|M.bovis_AF2122/97 T-----SPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAE
Rv0890c|M.tuberculosis_H37Rv T-----SPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAE
MLBr_01753|M.leprae_Br4923 S-----SPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTE
MSMEG_6828|M.smegmatis_MC2_155 G--------QSADELLALSRKIADDDPGRRQLLWAAAIECRMHGLPEHSR
Mflv_1156|M.gilvum_PYR-GCK IR---------AVELLERARADADNDAVLVTTLLSLGFCLGMTGSFTAQL
MAV_2364|M.avium_104 G-------EEADSILLGADVDDADEWLIARWGCLRAANLAWGCGDAEGAT
: .
MUL_2555|M.ulcerans_Agy99 QITDGLVDSLADRLG-------ELSVIYRDAWADAARRGRTVTQRLKEQL
MMAR_1324|M.marinum_M QITDGLVDSLADRLG-------ELSVIYRDAWADAARRGRTVTQRLKEQL
TH_3225|M.thermoresistible__bu GALLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVAL
Mvan_5002|M.vanbaalenii_PYR-1 GAVPRIAAAASAALDRLPESARPVDALLRGIVARITGGVSAGAAPLRLAM
MAB_3361|M.abscessus_ATCC_1997 GGAVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEAL
Mb0914c|M.bovis_AF2122/97 AAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECR
Rv0890c|M.tuberculosis_H37Rv AAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECR
MLBr_01753|M.leprae_Br4923 VARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAAD
MSMEG_6828|M.smegmatis_MC2_155 RDVVAEIGRLDDDPHDP----------LTAIALALADDTGKGAGLRARLP
Mflv_1156|M.gilvum_PYR-GCK ATVREAVAVAERAGVP----ALTSRALAMWVHVSFQAGNGLDSAALLRAV
MAV_2364|M.avium_104 RVLAEVKQRLATEGS---------LQLIDALDVSIGFFRGDIARTIELGP
MUL_2555|M.ulcerans_Agy99 DRLAELEP--------WDVMRVALAGYYVDLIDDFRSVLVPLADREIEGG
MMAR_1324|M.marinum_M DRLAELEP--------WDVMRVALAGYYVDLIDDFRSVLVPLADREIEGG
TH_3225|M.thermoresistible__bu TAMCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQA
Mvan_5002|M.vanbaalenii_PYR-1 DLMQEQARNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRA
MAB_3361|M.abscessus_ATCC_1997 TLIRCEADRPAN--TSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIA
Mb0914c|M.bovis_AF2122/97 DLADTIGDR-------FVSRHCSLWLSLAQMWAGNLTEALELSREITAEA
Rv0890c|M.tuberculosis_H37Rv DLADTIGDR-------FVSRHCSLWLSLAQMWAGNLTEALELSREITAEA
MLBr_01753|M.leprae_Br4923 DLAQEIGDR-------FVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGA
MSMEG_6828|M.smegmatis_MC2_155 QLVDTVGDSP------LLMLSLAFAAEAVTDRAGALKCWTHVQNQARNCG
Mflv_1156|M.gilvum_PYR-GCK DLEDPEDNTP-------IPFRASAARGLSLALTGRLAEADGQLAAVAQRS
MAV_2364|M.avium_104 RLCEPDVVP-------MATVWAAVATCGALTAVGRFSEVGRIAAAGVRAT
MUL_2555|M.ulcerans_Agy99 AATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRG
MMAR_1324|M.marinum_M AATIALATLALVTAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRG
TH_3225|M.thermoresistible__bu RDAGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVR
Mvan_5002|M.vanbaalenii_PYR-1 RDAGALEALPQVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYTPVR
MAB_3361|M.abscessus_ATCC_1997 REVGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATG-HAPIR
Mb0914c|M.bovis_AF2122/97 EASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIG
Rv0890c|M.tuberculosis_H37Rv EASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIG
MLBr_01753|M.leprae_Br4923 EAAHDTVTRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIG
MSMEG_6828|M.smegmatis_MC2_155 SLAEECEGLRGAANILLTEGHVEAAAMSAQTALHMAESMNIAMTAGSAAA
Mflv_1156|M.gilvum_PYR-GCK AQRGAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMVIA
MAV_2364|M.avium_104 AQCRAGAQRFAIGLAEVMAATAAGDYPAAERIHKRYAALATGLPAAEAMV
MUL_2555|M.ulcerans_Agy99 YLG--VISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFA
MMAR_1324|M.marinum_M YLG--VISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFA
TH_3225|M.thermoresistible__bu YHRL-IIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNG
Mvan_5002|M.vanbaalenii_PYR-1 YQTL-TLAAWRGEPADAEAVIEAAIADANARGEGRVLGAADYAFAVLYNG
MAB_3361|M.abscessus_ATCC_1997 YHSL-ILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNS
Mb0914c|M.bovis_AF2122/97 YAAM-TYAALAAGDVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAG
Rv0890c|M.tuberculosis_H37Rv YAAM-TYAALAAGDVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAG
MLBr_01753|M.leprae_Br4923 YAAM-VFAALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALAR
MSMEG_6828|M.smegmatis_MC2_155 ILA--RALVWQGQGERARHVLDRARHHLSPAPTILWNDDVHWAAGLAALC
Mflv_1156|M.gilvum_PYR-GCK FSIC-AAVAAYRGREDQARDQAAGALAQGGDYVALTVWASATLAFLEVSR
MAV_2364|M.avium_104 DAMLGVLQLTRGELQEACATLDRSISQLSQGFPLPWQLVVGALQAQAEGA
MUL_2555|M.ulcerans_Agy99 EGDYESAYLQATAITAPGEFPPLALHATRTLFDLVEAAVHTDRLNEARRH
MMAR_1324|M.marinum_M EGDYESAYLQATAITAPGEFPPFALHATRTLFDLVEAAVHTDRLNEARRH
TH_3225|M.thermoresistible__bu IGRYREALAAARTTCEYEDLG----FYSWCLHELVEAAARVGETDTAHRA
Mvan_5002|M.vanbaalenii_PYR-1 LGRYQEACSAARRACEYEDLG----VHSWVLAELVEAADHCGDTALAVSA
MAB_3361|M.abscessus_ATCC_1997 LGRYELAFMAARRACEHEDLG----LYSWCLIELIEAAVRCGEHDTAVKA
Mb0914c|M.bovis_AF2122/97 GDAIAARQFANDAVDATNGWH-----RMVALTIRARVATARGEPELARDD
Rv0890c|M.tuberculosis_H37Rv GDAIAARQFANDAVDATNGWH-----RMVALTIRARVATARGEPELARDD
MLBr_01753|M.leprae_Br4923 GDVIVARRLADNSVSATTGWH-----QMAALTTRARIAMAQGEPELARAD
MSMEG_6828|M.smegmatis_MC2_155 EADHTQALGHLTQMTLHRTSR------RWAIADLAEAAAGAEKADIARPL
Mflv_1156|M.gilvum_PYR-GCK GNYEQALEAAEPLVDLYRDFPGTELMSACFMPDAIESLIAVGRLDEAEPL
MAV_2364|M.avium_104 RGDSAAAAVALRRVEEAYGPHVAVFLPELELARAWERAAAGDTAGAQTQA
: .
MUL_2555|M.ulcerans_Agy99 VRAAKRLQFADAPPRLAIA----TGAAEALCASDERAPALFEKVLGHPAV
MMAR_1324|M.marinum_M VRAAKRLQFADAPPRLAIA----TGAAEALCASDERAPALFEKVLGHPAV
TH_3225|M.thermoresistible__bu LGDIEERAGASGTPWGLGA----LAGARALLADGDEADRLFREALDHLSR
Mvan_5002|M.vanbaalenii_PYR-1 LERLQERTADTGTDWGLGT----LAGAQALVADDDHAEALFEESIDRLAR
MAB_3361|M.abscessus_ATCC_1997 FGQLEERALAAQSDWSQGM----VARSRALITVGHDAEPHYREAIQRLTN
Mb0914c|M.bovis_AF2122/97 AHAALACGAELHIYQGMPD----AMELLAGLAGEVGSHSEGVRLLGAAAA
Rv0890c|M.tuberculosis_H37Rv AHAALACGAELHIYQGMPD----AMELLAGLAGEVGSHSEGVRLLGAAAA
MLBr_01753|M.leprae_Br4923 IHAALACGADIQASLGISD----SMELLAELISQGDNHRQAGRLFGAASA
MSMEG_6828|M.smegmatis_MC2_155 LAEAEEQAERLGIDSFLVH----RAHALLADSVAE-SEDRFRAALGAAER
Mflv_1156|M.gilvum_PYR-GCK IAAFERNGAELDRPWQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHAR
MAV_2364|M.avium_104 MQAAQTARKAGMHLVEMRAR---HAALRFGDRAQAARVDELASILNSPSA
:
MUL_2555|M.ulcerans_Agy99 ASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRA
MMAR_1324|M.marinum_M ASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRA
TH_3225|M.thermoresistible__bu SRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAERS
Mvan_5002|M.vanbaalenii_PYR-1 TRVAVHLARAHLRYGEWLRRALRRNDAREQLTLASGMFTRFGAAAFAERT
MAB_3361|M.abscessus_ATCC_1997 TRISAHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAERA
Mb0914c|M.bovis_AF2122/97 LRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDR---AWAEGAALSTDE
Rv0890c|M.tuberculosis_H37Rv LRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDR---AWAEGAALSTDE
MLBr_01753|M.leprae_Br4923 QREKTGEVRFKVWDAGYESAVAVLRGAMGCKDFDS---AWAEGAAMPIDD
MSMEG_6828|M.smegmatis_MC2_155 TGAELESARTHLLYGVWLRRRRRIVDARVHLSAALTAFDRAGAVPFAERA
Mflv_1156|M.gilvum_PYR-GCK LPMPFERARSALTLGEVLRRLRR-RDAAAAVRDALAQFEELGVPLWVARA
MAV_2364|M.avium_104 QAVAGHARGLAQHDGDLLDAAAHRFADLGALAFAADAAAQAASEHARRGD
.
MUL_2555|M.ulcerans_Agy99 RN--------ELRAAGTAVRHSAAVGP----APLTAQERLVAELAAKGLS
MMAR_1324|M.marinum_M RN--------ELRAAGTAVRHSAAVGP----APLTAQERLVAELAAKGLS
TH_3225|M.thermoresistible__bu RR--------ELIAVGEKVRRQPLTSG----DELTAQEAQIAGLAADGLT
Mvan_5002|M.vanbaalenii_PYR-1 RR--------ELIATGEKARRQPVTSG----AQLTAQESQIARLAGDGLT
MAB_3361|M.abscessus_ATCC_1997 ER--------ELRATGAKVRKRSASSE----KALTAQEAQIARMAGQGLT
Mb0914c|M.bovis_AF2122/97 AI--------AYAQRGRGERKRPARGW----GSLTPTERDVVRLVSEGLS
Rv0890c|M.tuberculosis_H37Rv AI--------AYAQRGRGERKRPARGW----GSLTPTERDVVRLVSEGLS
MLBr_01753|M.leprae_Br4923 AI--------TYAQRGRGNRKRPTTGW----ESLTPAEHNVIRLVSEGLD
MSMEG_6828|M.smegmatis_MC2_155 AA--------ELRAAGVTSAPRPGTHSGADAGALTPQELQIAQMAAAGMT
Mflv_1156|M.gilvum_PYR-GCK RI--------ALSGLAVSG---SAVGS-----ELTDSERRIAELAASGMS
MAV_2364|M.avium_104 RRKEVESSTWAHALAGQCGSRTPALDAAARPLPFSGRERQIVNLVAAGLS
. . :: * : :.. *:
MUL_2555|M.ulcerans_Agy99 NKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI
MMAR_1324|M.marinum_M NKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI
TH_3225|M.thermoresistible__bu NQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW----
Mvan_5002|M.vanbaalenii_PYR-1 NQEIGAQLFISTHTVDWHLRKVFVKLGITSRRQLRSASWAS-------
MAB_3361|M.abscessus_ATCC_1997 NQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR----------
Mb0914c|M.bovis_AF2122/97 NKDIAKRLFVSPRTVQTHLTHVYAKLGLASRVQLVDEAARRGSPS---
Rv0890c|M.tuberculosis_H37Rv NKDIAKRLFVSPRTVQTHLTHVYAKLGLPSRVQLVDEAARRGSPS---
MLBr_01753|M.leprae_Br4923 TKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN------
MSMEG_6828|M.smegmatis_MC2_155 NREIADRIYLSHRTVAAHLYKVFPKLGITRRNQLHAALGAPTGIA---
Mflv_1156|M.gilvum_PYR-GCK NRDVAETLFVSVKTIETNLSRVYRKLGIRSRAQLGRMLR---------
MAV_2364|M.avium_104 NREIADRLVISVRTVEGHLYRLFTKLGINNRDQLIQLIRRDAS-----
.:::. : :* :*: :* ::: * *: * *