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VGREAELRRSLAALSNAEFHGVALVGDAGVGKSTLARMLAKTVESAGRTVRFALGTQTGSAVPLGAFSHA VSLMAVNEPAVMLAAAHNTLSQDKNLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVTIRSGEPVLDAVT ALLKERLLLTVHVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSGNPLLLRGFLTAGRDTGALFRTAE GWQLRGPLRGDRELHDALEYRLQSLSSEEREVVEILATAGLLNWDILRDICDAEAVAALERRGLIRLVTD GSHAVAQLTHPMLGEAATRHAGMVRTRQLNGKLARALQKHERTGSRHLRLPHLQSRIRLAEFMLHSDMEP DLDVITEAARDALAMSNVQLGEELARFALDRGGGLPAALVLAEAVSWQGRGEEAGFVLAHAEPDGDDDWL IARWGCLRAANLFWGCGDAEAARREADTVKKRVSSEAGLHLIDALELSMAFFRGDVETTTELGPGLCESD AVPMATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSCGMGLHRFNIGISEIIAATDAGDDRAAERIY KRYAAMAEGLPGAEAMVDAMLGVVRLARGEFPAACAAFTRSISLFAKGFPSPWLVVVGAFQAQAEGARGD STAAAAALWRADRAYGPHAAVFLPELELARAWERAAAGDTQAATTHATQAAEIARAAGMHAAEMRTRHAA VRFGDRSQTARLERLARILDTPLAEAAADHARGLTQRDGDLLDAAAQQFADLGALACAADAAAQAAGEHA RRGDRGKKFESSAWAHALASRYELHTPAVEAAARPLPFSGRERQIVNLVAAGLSNREIADRLVISVRTVE GHLYRLFTKLGINSREQLTLLVAREPRGRRELLGHSNPSLGDQDDVHPHAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2362 | - | - | 100% (891) | TPR repeat-containing protein |
| M. avium 104 | MAV_2364 | - | 0.0 | 75.35% (860) | TPR repeat-containing protein |
| M. avium 104 | MAV_0578 | - | 4e-97 | 32.17% (886) | transcriptional regulator, LuxR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1236c | - | 2e-69 | 34.68% (571) | hypothetical protein Mb1236c |
| M. gilvum PYR-GCK | Mflv_4479 | - | 1e-127 | 35.27% (845) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv1204c | - | 2e-69 | 34.68% (571) | hypothetical protein Rv1204c |
| M. leprae Br4923 | MLBr_01753 | - | 9e-14 | 22.68% (957) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3907c | - | 1e-135 | 35.71% (868) | LuxR transcriptional regulator |
| M. marinum M | MMAR_4234 | - | 2e-61 | 33.68% (484) | hypothetical protein MMAR_4234 |
| M. smegmatis MC2 155 | MSMEG_2120 | - | 0.0 | 47.92% (866) | TPR repeat-containing protein |
| M. thermoresistible (build 8) | TH_4663 | - | 1e-80 | 33.44% (649) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_0955 | - | 5e-61 | 33.33% (483) | hypothetical protein MUL_0955 |
| M. vanbaalenii PYR-1 | Mvan_0243 | - | 0.0 | 51.95% (872) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2362|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
TH_4663|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 -------------------------------------------MTEKWTE
MAV_2362|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 -------------------MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPM
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
TH_4663|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_2120|M.smegmatis_MC2_155 MSGWPFVGRDDELREAAEALRDSS--RGVVLAGPSGVGKTALARALAGQL
Mvan_0243|M.vanbaalenii_PYR-1 LPDWPLVGRARELGRAIDALRPGSGFRGVVFVGEPGSGKTTLARAIAATL
MAV_2362|M.avium_104 ------MGREAELRRSLAALSNAE-FHGVALVGDAGVGKSTLARMLAKTV
MAB_3907c|M.abscessus_ATCC_199 ARSWQLLDRQTEFGAVRSAMADDS-TCGAVLVGAAGVGKTTLARAVTKSL
MMAR_4234|M.marinum_M MPIRWNVPQHAAALEQLDVALSDLARPGAVILGPDGVGKSTLARLAAEHF
MUL_0955|M.ulcerans_Agy99 -------------MEQLDVALSDLARPGAVILGPDGVGKSTLARLAAEHF
Mb1236c|M.bovis_AF2122/97 ----------MRVWKHVEAAVDSPDRCGVVLVGPHGVGKTLLAQLAAEQV
Rv1204c|M.tuberculosis_H37Rv ----------MRVWKHVEAAVDSPDRCGVVLVGPHGVGKTLLAQLAAEQV
Mflv_4479|M.gilvum_PYR-GCK ------MTAGLGLARTQVESAIVASRLRAVLVGAAGVGKTSMARKLARDY
TH_4663|M.thermoresistible__bu -----------------------------VLVGPAGAGKTELARTVLQHR
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
. . . .: :
MSMEG_2120|M.smegmatis_MC2_155 ETEGY----TIRYVLGTETGQAVPFGAFHHTLELS----DAHEPTVMLAA
Mvan_0243|M.vanbaalenii_PYR-1 RSEGV----TTRFVLGTDTGQAVPLGAFHRTLSIE----DPHEPAVMLAA
MAV_2362|M.avium_104 ESAGR----TVRFALGTQTGSAVPLGAFSHAVSLM----AVNEPAVMLAA
MAB_3907c|M.abscessus_ATCC_199 DAD-------VRWVACTESSRSIPLGVFAHWIQAS----GSRDPTALIAA
MMAR_4234|M.marinum_M AQRHP--ATVIRWVTGTPTERTVPFGAFSHLVEI----AELGKPAALLRA
MUL_0955|M.ulcerans_Agy99 AQRHP--ATVIRWVTGTPTERAVPLGAFSHLVEI----AELGKPAALLRA
Mb1236c|M.bovis_AF2122/97 MSEDGR-SGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPAALLRA
Rv1204c|M.tuberculosis_H37Rv MSEDGR-SGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPAALLRA
Mflv_4479|M.gilvum_PYR-GCK ARKHP--RLTSHWVSATASARDIPFAAFSHLIDV----SGGEEPTTLLRA
TH_4663|M.thermoresistible__bu RREQP--HTVLHWVAGTASASRIPFGAFSHLVET----GGGGEPATVLRT
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSH-LLRDLARPVRVMQL
:* .: : *. ::
MSMEG_2120|M.smegmatis_MC2_155 AHHTLSA-------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 AHRALAR-------------------------------------------
MAV_2362|M.avium_104 AHNTLSQ-------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 ARESIVS-------------------------------------------
MMAR_4234|M.marinum_M ARASLGRKV-----------------------------------------
MUL_0955|M.ulcerans_Agy99 ARASLGRKV-----------------------------------------
Mb1236c|M.bovis_AF2122/97 ARSSLTG-------------------------------------------
Rv1204c|M.tuberculosis_H37Rv ARSSLTG-------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK ARESLR--------------------------------------------
TH_4663|M.thermoresistible__bu ARESLCGPVLRD--------------------------------------
MLBr_01753|M.leprae_Br4923 CHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLL
.: :
MSMEG_2120|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0243|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_2362|M.avium_104 --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK --------------------------------------------------
TH_4663|M.thermoresistible__bu --------------------------------------------------
MLBr_01753|M.leprae_Br4923 TLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDN
MSMEG_2120|M.smegmatis_MC2_155 ------DPNVLIVVDDAQYLDPLSALLVQQLAVHGSIKLIVTMRSGATTS
Mvan_0243|M.vanbaalenii_PYR-1 ------EHNLVLAIDDAHLLDPLSALLVQQAATSDTARLIVTIRSGEVVP
MAV_2362|M.avium_104 ------DKNLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVTIRSGEPVL
MAB_3907c|M.abscessus_ATCC_199 ------TANPIIGIDDAHLLDDLSATLLHQIAVDHVGHVVATVRSGEPVP
MMAR_4234|M.marinum_M -----RQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-
MUL_0955|M.ulcerans_Agy99 -----RQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-
Mb1236c|M.bovis_AF2122/97 -----DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPP
Rv1204c|M.tuberculosis_H37Rv -----DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPP
Mflv_4479|M.gilvum_PYR-GCK -----SAHGLLLVVDDAHHLDTLSATLVHQLAVTDNAHIMLTVREGEPVP
TH_4663|M.thermoresistible__bu ----RTRTGLLLIVDDAHHLDTLSATLVHQVAVSTPASLLLTVRDGEPVP
MLBr_01753|M.leprae_Br4923 LRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPS-LTILATSREPIG
:: :*:.. * :.* :: :
MSMEG_2120|M.smegmatis_MC2_155 DAVTALWKEHLLVRLDVEPFSRAQTAEVASTVLGGEVDEHAVAELHRYSS
Mvan_0243|M.vanbaalenii_PYR-1 DAVTALWKEQLLMRVDLNAFDRTQTQELVDAVLDGEVDSSVVDRLHDLAG
MAV_2362|M.avium_104 DAVTALLKERLLLTVHVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSS
MAB_3907c|M.abscessus_ATCC_199 DAVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSR
MMAR_4234|M.marinum_M EAIAALWTDNLLDRIDVAPPD-----------------------------
MUL_0955|M.ulcerans_Agy99 EAIAALCTDNLLDRIDVAPPD-----------------------------
Mb1236c|M.bovis_AF2122/97 DAIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSL
Rv1204c|M.tuberculosis_H37Rv DAIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSL
Mflv_4479|M.gilvum_PYR-GCK DAVTALWKDSILSRHDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQ
TH_4663|M.thermoresistible__bu DAITALWKDDLLARIDIEPFSQAECERLLADALGGRVESASAERLYAISE
MLBr_01753|M.leprae_Br4923 VAGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRL
* .: *
MSMEG_2120|M.smegmatis_MC2_155 GSPMFLRGVLTAAMGDGVLVQAHGRWRLRGNLRPSPDLYELIASRVETLS
Mvan_0243|M.vanbaalenii_PYR-1 GSPLVLRGLIGAAREDGVLVRQGGRWRLHGRLRVGTDVHELVQTQLAGLT
MAV_2362|M.avium_104 GNPLLLRGFLTAGRDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLS
MAB_3907c|M.abscessus_ATCC_199 GNPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVD
MMAR_4234|M.marinum_M -----------------------------GKTKQS--EPADVDEFIAELP
MUL_0955|M.ulcerans_Agy99 -----------------------------GQTKQS--EPADVDEFIAELP
Mb1236c|M.bovis_AF2122/97 GNPLYLRHLID----GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALP
Rv1204c|M.tuberculosis_H37Rv GNPLYLRHLID----GGGLEHVDGRWRCRDEDRRP--LSGVIDEYLCALP
Mflv_4479|M.gilvum_PYR-GCK GNPLYLRHLVDAALGTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLP
TH_4663|M.thermoresistible__bu GNPLYLRHLVTGTVASGALREVEGIWQLRGEVALTPQLSTLIDQHLSALP
MLBr_01753|M.leprae_Br4923 DGMPLAIELAAARIRTLSLTEIADG--LDDRFRLLTGGARTAVRRQQTLR
. :
MSMEG_2120|M.smegmatis_MC2_155 AEELDVAEVVATADMLDWHVLLAICG---PDAVARAERRGAIQVTSAGSH
Mvan_0243|M.vanbaalenii_PYR-1 EGEFEVVEIVSAAEVLDWNVLRALCD---AEAIARTEHRGVIEFVDDGSH
MAV_2362|M.avium_104 SEEREVVEILATAGLLNWDILRDICD---AEAVAALERRGLIRLVTDGSH
MAB_3907c|M.abscessus_ATCC_199 DTVFSALKVLSMCEPLDIDTLCEIAS---DEAVDAAEIADLIRVERDGVR
MMAR_4234|M.marinum_M APARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEPDEP
MUL_0955|M.ulcerans_Agy99 APARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEPDEP
Mb1236c|M.bovis_AF2122/97 EPARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPDSDT
Rv1204c|M.tuberculosis_H37Rv EPARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPDSDT
Mflv_4479|M.gilvum_PYR-GCK EPVRSVLEFLAIDDPLSVDDLAALTG---IDAVDAAETCGVVTITDRAGA
TH_4663|M.thermoresistible__bu DQIRTVLAYLAIEEPLTVADLSDLVS---PEAVEAAEAAGAVTVDERGAD
MLBr_01753|M.leprae_Br4923 ASMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDR
:: * : . .
MSMEG_2120|M.smegmatis_MC2_155 AVVQPGHPIIGEVVRSRCPVSRTRQINTLVAEHLSAQLRVATDAS---AV
Mvan_0243|M.vanbaalenii_PYR-1 TLVRAGHPILGEVVRQRGGVARTRQLNTMLAQSISDFLGTDATHPYSVGA
MAV_2362|M.avium_104 AVAQLTHPMLGEAATRHAGMVRTRQLNGKLARALQKHERTGSRHLR--LP
MAB_3907c|M.abscessus_ATCC_199 TVVRFSHPMFGEAVRRRVGTASGRRLRGKLVRVLRDRD----------LG
MMAR_4234|M.marinum_M AVVYTAHPLFAKRARVALGDDGARQRRTELVTLLSQHP----------NE
MUL_0955|M.ulcerans_Agy99 AVVYTAHPLFAKRARVALGDDGARQRRTELVTLLSQHP----------NE
Mb1236c|M.bovis_AF2122/97 SEIFVGHPLYADRARAVLTAEHAHALRVSLVAQLAKHP----------SD
Rv1204c|M.tuberculosis_H37Rv SEIFVGHPLYADRARAVLTAEHAHALRVSLVAQLAKHP----------SD
Mflv_4479|M.gilvum_PYR-GCK LYAHPFHPIYTERVRSSLGLLAMRRLRKLLAGRMSVRA----------PG
TH_4663|M.thermoresistible__bu LIVHPAHPLYTETVRAGLGRLTRRSLRTALVARWSRRP----------PD
MLBr_01753|M.leprae_Br4923 LTMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNE--------VD
:.: .
MSMEG_2120|M.smegmatis_MC2_155 DVRTRIQLARFMTRAESPPD---TDLVTEAAASAVTMSDLVLGEQLARFA
Mvan_0243|M.vanbaalenii_PYR-1 DVRSRIQLARFMTCSDAEPD---LELITAAAADAVTMSNLVLAEQLARFA
MAV_2362|M.avium_104 HLQSRIRLAEFMLHSDMEPD---LDVITEAARDALAMSNVQLGEELARFA
MAB_3907c|M.abscessus_ATCC_199 TASNRIRLARLSIDCDEPVD---VDLLVTAAKDAVYLSNLPLGEELARAA
MMAR_4234|M.marinum_M HLSDRLRLASLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAA
MUL_0955|M.ulcerans_Agy99 HLSDRLRLASLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAA
Mb1236c|M.bovis_AF2122/97 HVSDQLRLSSLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAA
Rv1204c|M.tuberculosis_H37Rv HVSDQLRLSSLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAA
Mflv_4479|M.gilvum_PYR-GCK NLSTRLRMAALAMGTDEPPS---ADELVGLSWEAMRLGDLALGERLARAA
TH_4663|M.thermoresistible__bu NVSDRLRLAALAVNSQTPPP---ATDLIATSWEAMQLGDLLLGEQLARGA
MLBr_01753|M.leprae_Br4923 LVLARHRDHYMALGALLDTPG-DIDHEQLVEQVETELDNLRSAFAWSRET
: : : :.:: . :: :
MSMEG_2120|M.smegmatis_MC2_155 VEHGAGVNAALVLADAISWQGRGDEADALLARYPPDG------EDDLTVT
Mvan_0243|M.vanbaalenii_PYR-1 FDRGGGLPSAIALADAISWQGRGQEAEAILAAFDPDG------ADALMTV
MAV_2362|M.avium_104 LDRGGGLPAALVLAEAVSWQGRGEEAGFVLAHAEPDG------DDDWLIA
MAB_3907c|M.abscessus_ATCC_199 VDGGGGLQAAAMLSRSLLWQGRPEQAEEILAAFDPDD------LDELSLV
MMAR_4234|M.marinum_M LDRSGGLQARLVLGQALAWRGRGREAGQVLTAVDPGQ------LSEAELM
MUL_0955|M.ulcerans_Agy99 LDRSGGLQARLVLGQALAWRGRGREAGQVLTAVDPGQ------LSEAELM
Mb1236c|M.bovis_AF2122/97 LDRSDALAARLPLAYALGWQGRGREADAVLAAVNPAE------LTETELM
Rv1204c|M.tuberculosis_H37Rv LDRSDALAARLPLAYALGWQGRGREADAVLAAVNPAE------LTETELM
Mflv_4479|M.gilvum_PYR-GCK LDQADGLAARLPLAHSLSWQGRGRDADDVLNPVDPDT------LTQWDLM
TH_4663|M.thermoresistible__bu LGQSDTLAARLPLAHALAWQGRGREADDVLAAVDPDR------LTEFDIM
MLBr_01753|M.leprae_Br4923 GDIAGALQLASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLA
. : * :*: :. :
MSMEG_2120|M.smegmatis_MC2_155 RWGCQRAANLFFVCGRPEPAWEVLAKTRDAVGSGKLTGLVTAMEVAFTYF
Mvan_0243|M.vanbaalenii_PYR-1 RWGCLRGANLFFGCGHSDGAWAALATVRERVASEDLLSLVTAMEVSLAFF
MAV_2362|M.avium_104 RWGCLRAANLFWGCGDAEAARREADTVKKRVSSEAGLHLIDALELSMAFF
MAB_3907c|M.abscessus_ATCC_199 LWGIPRISIAFWSMGENERAHELLALLHERVRHHILKPVVDATDAAIALH
MMAR_4234|M.marinum_M AWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTATFAMN
MUL_0955|M.ulcerans_Agy99 AWAVPQAANQFWMLGEPERATAFLQTTRNRVTDLTARTTLDALTATFAMN
Mb1236c|M.bovis_AF2122/97 AWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAATFAMN
Rv1204c|M.tuberculosis_H37Rv AWAIPRAANRFWMLNEPERATAFLQTTRSRVTEPTARSTLDALAATFAMN
Mflv_4479|M.gilvum_PYR-GCK AWTLPKAANRFWMLSESEEAVEYLRQMRARITERGALHTIDALAATFAMN
TH_4663|M.thermoresistible__bu AWTLPKAANQFWMLSESAEAIALLDRMRTRLHQPAAVTAFDALAATFAMN
MLBr_01753|M.leprae_Br4923 RAVANKVMLHAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTAC
: . . : : . :::
MSMEG_2120|M.smegmatis_MC2_155 ------SADMAGAAAAGSAALATEMMP-AATVWVALATAGALAKSGRFSE
Mvan_0243|M.vanbaalenii_PYR-1 ------SGDVPVAVRLGQAALATERMP-MATVWAAMATAGALSLSGRLDE
MAV_2362|M.avium_104 ------RGDVETTTELGPGLCESDAVP-MATTWAAVPTCAALAATGRYSE
MAB_3907c|M.abscessus_ATCC_199 ------ENRFDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHE
MMAR_4234|M.marinum_M ------SGNVPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFAD
MUL_0955|M.ulcerans_Agy99 ------SGNVPRAITLATEVLAEPSADDTAIAWAASAAALASARMGRFAD
Mb1236c|M.bovis_AF2122/97 ------SGNLPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGD
Rv1204c|M.tuberculosis_H37Rv ------SGNLPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGRFGD
Mflv_4479|M.gilvum_PYR-GCK ------AGDPAEAVTVAKGILAADDAQDLAVAWASAAATLSSARMGRFAE
TH_4663|M.thermoresistible__bu ------AGQPRTALELAGRVLQTPESQDLAVAWAAATATLSSARMARFDE
MLBr_01753|M.leprae_Br4923 GFSSGYDTEVARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVA
: .
MSMEG_2120|M.smegmatis_MC2_155 VAAVVRTGEHAASRCESGPHRYSLPLAEVLAGTLAGEFDDAQRACDRYAA
Mvan_0243|M.vanbaalenii_PYR-1 VRPIARQGLQAARYCESGPQHYTIGLAEVLAYTASGDMDAADHACERYSA
MAV_2362|M.avium_104 VGRIADIGVRAAMSCGMGLHRFNIGISEIIAATDAGDDRAAERIYKRYAA
MAB_3907c|M.abscessus_ATCC_199 FEPIAQRCRDDKKRTTDGLIAAMVRYCDVLALTYTGQLDLAEERVAEYTK
MMAR_4234|M.marinum_M VPQLAQRASEAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTD
MUL_0955|M.ulcerans_Agy99 VPQLAQRASEAEH---PGLLRFTVGLAQITTLLMAGEVAQAQELAQRFTD
Mb1236c|M.bovis_AF2122/97 VDRLAERASAAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTD
Rv1204c|M.tuberculosis_H37Rv VDRLAERASAAEH---PGLLRFTVGLAQITSLLLAGDVAPAQELAKRFTD
Mflv_4479|M.gilvum_PYR-GCK VDGLAQRGLDAAH---PGLLRFTLGLGQTLALIMNADVASAEHLARHYLS
TH_4663|M.thermoresistible__bu VETHAARGLAAQH---PGLLRFTIGLGQITRLILAGXLTRADFLAHHYLS
MLBr_01753|M.leprae_Br4923 LRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVA
. . . * .
MSMEG_2120|M.smegmatis_MC2_155 ASSD-IPQADVMVTALAGRMKLARGQLEDACEQLQAAVWSMAAKLPPGWP
Mvan_0243|M.vanbaalenii_PYR-1 MTCG-VPQAEAIVNALVGRVNFARGLLAAACDALSTSLWTMSESLPSGWV
MAV_2362|M.avium_104 MAEG-LPGAEAMVDAMLGVVRLARGEFPAACAAFTRSISLFAKGFPSPWL
MAB_3907c|M.abscessus_ATCC_199 FSSAGQFLAWAIARIMAGVVATQRGLFREAIEAFEQALAAQRADRPLPWQ
MMAR_4234|M.marinum_M FAEL-QQPGRAIGEVLLAHVLIVKGEFGAAAAMLEPAAAELERTG-YSWG
MUL_0955|M.ulcerans_Agy99 FAEL-QQPGRAIGEVLLAHVLIVKGEFGTAAAMVEPAAAELERTG-YSWG
Mb1236c|M.bovis_AF2122/97 FA------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv FA------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK FSEF-QQPGRAIGEVLLGHTLLASGRFGDAVTLLRQAAAALTYTG-YSWG
TH_4663|M.thermoresistible__bu FCEF-QQPGRAIGEVLLAHILIARGDLPTATTLLRQAAAALSSTG-YSWG
MLBr_01753|M.leprae_Br4923 GAEAAHDTVTRTFGLYVQTRALVHRDVSAALVTAG-LVVEAAAELSGVYQ
MSMEG_2120|M.smegmatis_MC2_155 MLVASWLAQAEGARGNAEAAAVALTKAEAEVGPQVEVFAPELELARAWRA
Mvan_0243|M.vanbaalenii_PYR-1 MLVAAWLAQAEAARGNADGAAAALARAEDANGPQVAVFVPELELARSWHR
MAV_2362|M.avium_104 VVVGAFQAQAEGARGDSTAAAAALWRADRAYGPHAAVFLPELELARAWER
MAB_3907c|M.abscessus_ATCC_199 LPARLLLARAYAALGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLV
MMAR_4234|M.marinum_M PLSLMLLATAIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAK
MUL_0955|M.ulcerans_Agy99 PLSLMLLATAIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAK
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK PLALTGLAQALGQQGRAADASAVLTRAEASHGMRSALYAPDLALARAWTL
TH_4663|M.thermoresistible__bu PLALMQLTQVLGARGDADGASEALRRAEHSHGTRSELYAPELALX-XXXW
MLBr_01753|M.leprae_Br4923 GIGYAAMVFAALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVAL
MSMEG_2120|M.smegmatis_MC2_155 AA-------------AGETSRAQHHAVLAAQNAHAAGMTAVELTALHTST
Mvan_0243|M.vanbaalenii_PYR-1 AC-------------VGQTTTARDHALRAAQTARVKGMWAVEMCALHTAV
MAV_2362|M.avium_104 AA-------------AGDTQAATTHATQAAEIARAAGMHAAEMRTRHAAV
MAB_3907c|M.abscessus_ATCC_199 AA-------------RGSDRGAVDAARRAADAAHSAGQYALEAEALHHAA
MMAR_4234|M.marinum_M AT-------------VRDQAGALFDTREAARAAERGKQSAVALCVWHDAV
MUL_0955|M.ulcerans_Agy99 AT-------------VRDQAGALFDTREAARAAERGKQSAVALCVWHDAV
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK AA-------------ARDLRGAVASARDAVHAAVQSGQDAVALRALQDCA
TH_4663|M.thermoresistible__bu RG-------------LRDESGHLAAYRITVDDRLP-----ETLADLWD--
MLBr_01753|M.leprae_Br4923 ARGDVIVARRLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHA
MSMEG_2120|M.smegmatis_MC2_155 RFGDRTVDARIQQLPTELDCPLGEAIALHSSGLAGHDGNRLVTAADRFER
Mvan_0243|M.vanbaalenii_PYR-1 RFGDRSQSARLRQCAAQLDSPLAEAIAAHGIGLSDHDGDRLDAAADMFDR
MAV_2362|M.avium_104 RFGDRSQTARLERLARILDTPLAEAAADHARGLTQRDGDLLDAAAQQFAD
MAB_3907c|M.abscessus_ATCC_199 RFGDRTVGRRIESLCTRVHGPLTGLYARHALAVAHSDITGLEAVSADFEA
MMAR_4234|M.marinum_M RLGDTRALAPVTRLAAEIDCKVGNIVVRHARALADNDAGALASVADELAA
MUL_0955|M.ulcerans_Agy99 RLGDTRALAPVTRLAAEIDCKVGNIVVRHARALANNDAGALASVADELAA
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK RLGDTHGLATAVRLSDRIGCVTGPLCVAHLRALAAGDGAALDAVSADLET
TH_4663|M.thermoresistible__bu --GSAAEVWTAIEFS---GTTAHPMITAG----------------CALRS
MLBr_01753|M.leprae_Br4923 ALACGADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGE
MSMEG_2120|M.smegmatis_MC2_155 IGAMVLAGDAAAHASREFGRRGERGNELEASTRAHWLASRC-GAVTPALR
Mvan_0243|M.vanbaalenii_PYR-1 LGAAAMAADASAHAAREHARAGARVKELEATTRAHWLAGRN-CVRTPAVT
MAV_2362|M.avium_104 LGALACAADAAAQAAGEHARRGDRGKKFESSAWAHALASRY-ELHTPAVE
MAB_3907c|M.abscessus_ATCC_199 AGLLLSAADAAAQAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAIL
MMAR_4234|M.marinum_M IGMHAAAADAAAQAERAGGR------------------------------
MUL_0955|M.ulcerans_Agy99 IGMHAAAADAAAQAERAGGR------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK AGLPAAAADAAAQATFAHQRRGDRAGEVASRSRASRLSQVCGAPATPALE
TH_4663|M.thermoresistible__bu EKKPEAAGPLPALTPQRGLHR--PALEALAPTSGRRLPG-----------
MLBr_01753|M.leprae_Br4923 VRFKVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRG
MSMEG_2120|M.smegmatis_MC2_155 CAADPLP----LTPREWEIANLVSSGLSNRQVADRLCLSVRTVDGHLYRM
Mvan_0243|M.vanbaalenii_PYR-1 AIEDPLP----ITDREREIAVLVGESLTNREIAERLGVSVRTIDGHLYRI
MAV_2362|M.avium_104 AAARPLP----FSGRERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRL
MAB_3907c|M.abscessus_ATCC_199 AAAKPLP----ISSREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRA
MMAR_4234|M.marinum_M --------------------------------------------------
MUL_0955|M.ulcerans_Agy99 --------------------------------------------------
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK QVLNPMP----LTGREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRA
TH_4663|M.thermoresistible__bu ---EPVP----LPDGLLDSLFWPVRGVRSTARQRRTARQVETES------
MLBr_01753|M.leprae_Br4923 NRKRPTTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRI
MSMEG_2120|M.smegmatis_MC2_155 FAKLGVADRDQLAKLIRFRPAT-----------------------
Mvan_0243|M.vanbaalenii_PYR-1 FAKLSIEDREQLARLFRIRPAT-----------------------
MAV_2362|M.avium_104 FTKLGINSREQLTLLVAREPRGRRELLGHSNPSLGDQDDVHPHAG
MAB_3907c|M.abscessus_ATCC_199 RMKLDADDREEFAKIVGSDLKPPEAS-------------------
MMAR_4234|M.marinum_M ---------------------------------------------
MUL_0955|M.ulcerans_Agy99 ---------------------------------------------
Mb1236c|M.bovis_AF2122/97 ---------------------------------------------
Rv1204c|M.tuberculosis_H37Rv ---------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK CMKFGVPDRAALASTVGGMHGREGTA-------------------
TH_4663|M.thermoresistible__bu ------VDTAPVSRT------------------------------
MLBr_01753|M.leprae_Br4923 YSKLGLTSRVQLVQEAARHN-------------------------