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LCGRDRELSELGEHVAAAEHTARLVVLTGEPGIGKTALLRDLTQRHGAWWALGASWETDLPGGVLAQLMQ DDVPDDPLDGAAHLVDHVRAAGVRLLLVDDAHHADVESLQALSTLVRHQRDLPVLVVLATQSVDALPIPL AADDVVELTGLPVAAVVELARLRGITIHPTLADRLTRHAGGNPRDVLALFDEVPASAWARLDSSLPAPRH VVERVATQLDSCGPAGRALVQALAVLGAAGGGDATDATDTVTLAEAADLAGLSGPSEPLAALDEAVDAGL VTHVVHFEPRLTDGLTGPAVLTLLGARATAEAHRRAAEVITDPRRRLRHRVAAAAAPDEALAGEVDALAR ASGADGAWALAATLFHDASRLTSDPLLRDERLTRSVDALVAAGDCGAAAQLIPVVESLRETPLRNAVLAY LAILRGRATEAEVRLRRAWDIVNAERDPETAALIAQRYVLHSLVRGRGTELVRWADTALRLADRESPTAV ESAAVRGLGLAAAGRAEQATAAYDELAERITHGAQAQRVTLGRGWLQLIRDDVDGARSNLESAIATANLG GSSRITLWAMAWLARAHFVSGDWDAALATVVSGRDLAASSGITITTPLLEWIAAQISALRGDWETAHAAV QAADRVTQDYEMMRIPTILARAQVAEAEADYPKVRRVLEPLAALAARAPGTVLTEPGYWPWPDVLANALV IDGALDEADEFLRPHEEVARERGHRSAMARLGYARGRLLGARGELSAARARFEESLALLDGLPLRYDRAR VNFAYGQTLRRAGKRRDADAVIATARDLYLSLGAHTYVARCDRELKAGGLHQLRGSRDSVELTPQEDAVT ALVAQGLSNREVAAELYVSPKTVQYHLTRVYAKLGVRSRAELAALRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1901 | - | - | 100% (888) | DNA-binding HTH domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1691 | - | 4e-45 | 27.87% (951) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 7e-43 | 27.02% (966) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2515c | - | 9e-17 | 25.83% (960) | LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1352 | - | 0.0 | 59.00% (683) | tetratricopeptide TPR_4 |
| M. tuberculosis H37Rv | Rv2488c | - | 9e-17 | 25.83% (960) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01753 | - | 5e-14 | 24.39% (488) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3361 | - | 5e-42 | 27.05% (928) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 1e-35 | 25.21% (944) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 1e-18 | 26.29% (947) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3225 | - | 2e-42 | 26.82% (988) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 2e-26 | 30.62% (418) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_5653 | - | 7e-45 | 26.81% (966) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1901|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
MLBr_01753|M.leprae_Br4923 ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD
Mvan_5653|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 ------------------MLCGRDRE-----LSELGEHVAAAEHT-ARLV
Mflv_1352|M.gilvum_PYR-GCK --------------MAPVTFVGRSGD-----LDELIRRTAATVSDGSAVV
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu ----------MSSRDGDVVLHGRAAE-----IATLRDVMSTARAGSSRVL
MMAR_0085|M.marinum_M --------------MPTVTLVGRHRE-----QQQLQQLLDAARRGESGVL
Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
MLBr_01753|M.leprae_Br4923 LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ
Mvan_5653|M.vanbaalenii_PYR-1 ------------MMSGVGGGYGLTAAS-----AAAVDDFLESARRHPAGM
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 -------------MIGGELLIGRDSE-------LAAIRRALNGADHHRGV
MSMEG_1901|M.smegmatis_MC2_155 VLTGEPGIGKTALLRDLTQRHG-AWWALGAS---WETDLPG-----GVLA
Mflv_1352|M.gilvum_PYR-GCK TVRGAPGIGKTALLRQVAATVPNSRWATAVP---WESTVDG-----AVLS
MAB_3361|M.abscessus_ATCC_1997 MLRGQAGVGKTALLRYVLGKASGQLIAQASG---IQSEMELAFAGLQQFC
TH_3225|M.thermoresistible__bu VLHGEAGVGKTALLGQLLGDAAGMRCVQVAG---VESDMELAYAGLHQLC
MMAR_0085|M.marinum_M VLRGDAGIGKTTLLTDLVDNAPDLRVLRVRG---AEMEMELTYSGVQQLC
Mb2515c|M.bovis_AF2122/97 PVEQGEGDSFLVAFARASDAVACALGLQRAP---LAPIRLRIGMHTGEVS
Rv2488c|M.tuberculosis_H37Rv PVEQGEGDSFLVAFARASDAVACALGLQRAP---LAPIRLRIGMHTGEVS
MLBr_01753|M.leprae_Br4923 QVVQGVRGNFLATFARASDATACALDLQLAP---IVPVRFRIALHTGEVQ
Mvan_5653|M.vanbaalenii_PYR-1 LIEGDAGIGKTTMWNTVVQRAAEAGFVVLTARAGQAESGLAHAAVADLLS
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 VIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQALPLGAFIGLLG
MSMEG_1901|M.smegmatis_MC2_155 QLMQDDVPDDPLDGAAHL--VDHVRA------------------------
Mflv_1352|M.gilvum_PYR-GCK QLS-------PEPGAEQL--ARALAG------------------------
MAB_3361|M.abscessus_ATCC_1997 APLTKYSGAIPDPQREAL--TIAFGTRSGPPPDRFLIGLAVLSLLAAAAE
TH_3225|M.thermoresistible__bu APLLDRLDDLPSPQRDVL--NVAFGRGAGPAPGRFLVGLAVLNLLAAAGA
MMAR_0085|M.marinum_M GPLMSLIGQLPEPQLDAL--EIALGRKRGRAPDRLLLGLAVLTLVGEASR
Mb2515c|M.bovis_AF2122/97 SP-DEGNCVGPTIDRTAR--LRELAHGGQTVLSGTTSDLVADLLPKDAWL
Rv2488c|M.tuberculosis_H37Rv SP-DEGNCVGPTIDRTAR--LRELAHGGQTVLSGTTSDLVADLLPKDAWL
MLBr_01753|M.leprae_Br4923 ISNDDVNNVVFMMVQAAG--LLDLACGGQTVLSSITGDLVVDGLPADTWL
Mvan_5653|M.vanbaalenii_PYR-1 AVDPEIVDALPDMQRLAAGRVQLRDHAGGRPADERATAAALLSAVHAAGA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 DAMSEPLTSVRRVIETFV----------------------------ARQR
MSMEG_1901|M.smegmatis_MC2_155 AGVRLLLVDDAHHADVESLQALSTLVRHQRDLPVLVVLATQSVDALPIPL
Mflv_1352|M.gilvum_PYR-GCK DDPTLLVVDDAQHADSASLQALSTLIRHHRSLPVLLVLVTDG-HPLPVPG
MAB_3361|M.abscessus_ATCC_1997 HQPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRD--GTDSEL
TH_3225|M.thermoresistible__bu DQPLLCVIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRD--DIHEAL
MMAR_0085|M.marinum_M ASPILCVVDDAQWVDSASVQALAFVARRIHVDPVAMVFATRD--RGPDAL
Mb2515c|M.bovis_AF2122/97 NDLGTYRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRL
Rv2488c|M.tuberculosis_H37Rv NDLGTYRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRL
MLBr_01753|M.leprae_Br4923 VDLGSHLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTF
Mvan_5653|M.vanbaalenii_PYR-1 RAPVLIAIDDVQWLDASSRAVLAFAARRLKG-AVGVVATERTGQQSQERA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 RGRVVVGVDDAHLLDGLSALVVHQLAQSGGVRLVVTVRTGSHQPDAVTAL
MSMEG_1901|M.smegmatis_MC2_155 AAD---DVVELTGLPVAAVVELARLRG-ITIHPT----------------
Mflv_1352|M.gilvum_PYR-GCK LDG---DELVMTGLDVREVAALASARG-HVLPAL----------------
MAB_3361|M.abscessus_ATCC_1997 AGL---PELTVHGLRAADAGTLLDSVIPGLLDER----------------
TH_3225|M.thermoresistible__bu VGV---PALAVPGLADADARTLLEHMFPGAIDAN----------------
MMAR_0085|M.marinum_M TGH---CELSLQGLEDHDARLVLSTAIPGRLNDS----------------
Mb2515c|M.bovis_AF2122/97 VGR---VDEVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPD
Rv2488c|M.tuberculosis_H37Rv VGR---VDEVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPD
MLBr_01753|M.leprae_Br4923 VGR---AAQIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSG
Mvan_5653|M.vanbaalenii_PYR-1 ASW---LQVGTGGLARVQVAPMSLGALHSMLSDRLG--------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 WKDDLLTRLDLEPLSAAATREVIESTLGGPVDAR----------------
MSMEG_1901|M.smegmatis_MC2_155 -----------------------------------------LADRLTRHA
Mflv_1352|M.gilvum_PYR-GCK -----------------------------------------MVDRLTRHT
MAB_3361|M.abscessus_ATCC_1997 -----------------------------------------VRDRIVAET
TH_3225|M.thermoresistible__bu -----------------------------------------VRDRLVAES
MMAR_0085|M.marinum_M -----------------------------------------VAETVLAEA
Mb2515c|M.bovis_AF2122/97 GVWYVNLAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVV
Rv2488c|M.tuberculosis_H37Rv GVWYVNLAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVV
MLBr_01753|M.leprae_Br4923 ELSYFDLAPDTDHDIFPIT--------------VLDNLRRCIGDRRMLMV
Mvan_5653|M.vanbaalenii_PYR-1 -----------------------------------RRFSRPAIVRIAEAS
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 -----------------------------------------CAARFRRLT
MSMEG_1901|M.smegmatis_MC2_155 GGNPRDVLALFDEVPASAWAR-------LDSSLPAPRHVVERVATQLDSC
Mflv_1352|M.gilvum_PYR-GCK AGHPGHVRALLDELPAQTWSR-------LDAPLPAPREVVAQVERELAAA
MAB_3361|M.abscessus_ATCC_1997 QGNPLALLELPRDMTAEELAGG----FGWPDGGRLAGQIEQTFLRRVQQL
TH_3225|M.thermoresistible__bu RGNPLALLEVPRTYAVGELAGG----FVSPGAGSAPSRIEENYVHRIRAL
MMAR_0085|M.marinum_M NGNPLALLELHNALIRGELAGG----YGLANATRTETQIERTFVSRLRAL
Mb2515c|M.bovis_AF2122/97 LDNCEHLLDGCAALIVALLGACPA--LRVLATSREPIAVAGEQIWRVPPL
Rv2488c|M.tuberculosis_H37Rv LDNCEHLLDGCAALIVALLGACPA--LRVLATSREPIAVAGEQIWRVPPL
MLBr_01753|M.leprae_Br4923 LDNCEYLLDVCANVMTTLLGACPS--LTILATSREPIGVAGEVIWRVSML
Mvan_5653|M.vanbaalenii_PYR-1 GGNPLYALELARVMDGDMLRPG----------VRLPSTLAEVVGLRVDKL
MUL_2555|M.ulcerans_Agy99 -------------------------------MPALSANLVASIDRHPERI
MAV_0578|M.avium_104 GGNTLFLRQLLSDQMAAGRMRRVAGVWMWDGDVAVSASLSDTVGRQLGRL
: .
MSMEG_1901|M.smegmatis_MC2_155 GPAGRALVQALAVLGAAGGGDATDATDTVTLAEAADL---AGLSGPSEPL
Mflv_1352|M.gilvum_PYR-GCK GDGGRALAFALAVLG-----------EEATLSEAVLL---AGID---DPL
MAB_3361|M.abscessus_ATCC_1997 PAHTQTLLLAAATDPLG---------DVTLLARAAQQ---LGIP-----M
TH_3225|M.thermoresistible__bu PAQTRRLLLIAAAEPIG---------DSALFLRAAAL---MGIA-----V
MMAR_0085|M.marinum_M PSETKTFLLVAAAESTA---------RPEWLWAAAHR---LGIG-----P
Mb2515c|M.bovis_AF2122/97 G-HGEAIELFTDRAREA---------RPELEITADNL---ALVTEICHRL
Rv2488c|M.tuberculosis_H37Rv G-HGEAIELFTDRAREA---------RPELEITADNL---ALVTEICHRL
MLBr_01753|M.leprae_Br4923 SPADEAVELFTERAALV---------QPGFSVTDGNR---QIVTEICQRL
Mvan_5653|M.vanbaalenii_PYR-1 DDDVRDVLLVAASVTQP---------TVDLLAQTLAVRAEQ--------V
MUL_2555|M.ulcerans_Agy99 TLRCDDLQSVFAELGAG---------------------------------
MAV_0578|M.avium_104 TPPLALVVDTLSQCEPLP---------VDLLCDLASR----------EDL
.
MSMEG_1901|M.smegmatis_MC2_155 AALDEAVDAGLVTHVVHFEPRLTDGLTGPAVLTLLGARATAEAHRRAAEV
Mflv_1352|M.gilvum_PYR-GCK AAVAAATGAGLVRTGDPLEPRLRDPLAAAAVLDVCGVQATADAHRRAADV
MAB_3361|M.abscessus_ATCC_1997 HAIAPAEAADLVELST--RVRFRHPLVRSAVYISANPLERRRIHGVLAGA
TH_3225|M.thermoresistible__bu DALAPAEAARVIQFGP--RMRFFHPLMRSAAYRAADPRDRRAVHRALAEA
MMAR_0085|M.marinum_M EAAAPAEAAGLIAAQG--SVRFRHPLIRAAVYHSSSAAERRRVHAALAAS
Mb2515c|M.bovis_AF2122/97 DGIPLAIELAASRVRALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRAS
Rv2488c|M.tuberculosis_H37Rv DGIPLAIELAASRVRALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRAS
MLBr_01753|M.leprae_Br4923 DGMPLAIELAAARIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRAS
Mvan_5653|M.vanbaalenii_PYR-1 TALLESAEVEGVIAIEGNRVRFTHPLLASGIYDSAAPARRREFHRRLADI
MUL_2555|M.ulcerans_Agy99 --------------------------PGDRVAALPGDRTRRRVCGPACEL
MAV_0578|M.avium_104 VAAEAMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLATR
MSMEG_1901|M.smegmatis_MC2_155 IT-------DPRRRLRHRVAAAAAPDEALAGEVDALARASGADGAWALAA
Mflv_1352|M.gilvum_PYR-GCK VT-------DPVARLRHRVAATPVPDEALADEVDALARSSGADGEWSRAA
MAB_3361|M.abscessus_ATCC_1997 TDP----GADPDRRAWHRAHAAAGTDEAIAWELEQSAGRAQAKGGVLAAA
TH_3225|M.thermoresistible__bu TDP----GADPDRRAWHAANGVTGTDDAVAAELEKSAARAQQRGGIAATA
MMAR_0085|M.marinum_M IAG----PDDDDHRVWHRAHAAEAPDAQTADDLERSAERARARGGLSAAA
Mb2515c|M.bovis_AF2122/97 VDWSHALLTGPEQVLFRRLAVFPSGFDLDGAQAAAAGGDVQRYEVVDLLS
Rv2488c|M.tuberculosis_H37Rv VDWSHALLTGPEQVLFRRLAVFPSGFDLDGAQAAAAGGDVQRYEVVDLLS
MLBr_01753|M.leprae_Br4923 MDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRLT
Mvan_5653|M.vanbaalenii_PYR-1 QT-------QPELRARHLALAATVADDATLATLDAAADSARARGAPAAAA
MUL_2555|M.ulcerans_Agy99 SGGRFRPSARPQSCPGLTEAASPGRSRGPLHLARCAAELTIRRGDACQAI
MAV_0578|M.avium_104 LAQ------DQDADMQATVRRALLTLESDLDPQPELYLESARHAMTLLDL
MSMEG_1901|M.smegmatis_MC2_155 TLFHDASRLTSDPLLRDERLTRSVDALVAAGDCGAAAQLIPVVESLRETP
Mflv_1352|M.gilvum_PYR-GCK VLFRDAARLTAAPLLRDERLTRSVDALVAAGDCVGAAAMVPTVENLRETP
MAB_3361|M.abscessus_ATCC_1997 AFLQRATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDP
TH_3225|M.thermoresistible__bu TFLERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSA
MMAR_0085|M.marinum_M SFLEHATKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAAADDE
Mb2515c|M.bovis_AF2122/97 LLADKSLVVTDDSDGRTRYRLLETVRQYALEKLRESGDADAVRARHRDHY
Rv2488c|M.tuberculosis_H37Rv LLADKSLVVTDDSDGRTRYRLLETVRQYALEKLRESGDADAVRARHRDHY
MLBr_01753|M.leprae_Br4923 MLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHY
Mvan_5653|M.vanbaalenii_PYR-1 ELVELAIRLGGD---RVSRRIRAAEHHYVAGDMPRAAELLDQVTGDLRPG
MUL_2555|M.ulcerans_Agy99 ELLRRAGELSDRPRRREQLLASAAFVALQAAQLDEAERLLADAGLGGGAS
MAV_0578|M.avium_104 DLADRLANAAARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGDA
:
MSMEG_1901|M.smegmatis_MC2_155 LRNAVLAYLAILR-----GRATEAEVRLRRAWDIVNAERDPETAALIAQR
Mflv_1352|M.gilvum_PYR-GCK LRNATLAYLAILR-----GRATEAEVRLRRAWDIVHIDRDTDTAAFIAQR
MAB_3361|M.abscessus_ATCC_1997 LARARATRLR-----------AKIAFAESRVGAFGSVTVSEAAIGLVEAA
TH_3225|M.thermoresistible__bu LEWARAVHLR-----------AQLEFARSRAGDAGGPPVGQTAAALLTAA
MMAR_0085|M.marinum_M LIAARCELIR-----------AKIAFAASRG--------SDAPPLLLAAA
Mb2515c|M.bovis_AF2122/97 AAVAAGLDAPSVAGHERRLNQAELEIDNLRAAFAFSRENGDTGHALLLAS
Rv2488c|M.tuberculosis_H37Rv AAVAAGLDAPSVAGHERRLNQAELEIDNLRAAFAFSRENGDTGHALLLAS
MLBr_01753|M.leprae_Br4923 MALGALLDTPGDIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQLAS
Mvan_5653|M.vanbaalenii_PYR-1 VLRAIALNLR---------------------AGVRIFEDDYAGAVVLLER
MUL_2555|M.ulcerans_Agy99 ASALLISSFIS---------------------LYRYGDVTATHRRLVERL
MAV_0578|M.avium_104 SDRHYWATVRAAN------------------LVWMLGRPADAALVLDGLA
.
MSMEG_1901|M.smegmatis_MC2_155 YVLHSLVRGRGTELVRWADTALRLADRESP----TAVESAAVRGLGLAAA
Mflv_1352|M.gilvum_PYR-GCK HVLHALVHCQGEELVAWADRALALAERDSP----AGIEAAAIRGLGLLAS
MAB_3361|M.abscessus_ATCC_1997 RCLENLDDNLARETYLDAVGAAMYGGRLCP--RGGAVEVAEPARLAPAGA
TH_3225|M.thermoresistible__bu QLLQDVDAPAARESYLEAFAALMYAGRLAP--SGALLEAADAVQAAFARA
MMAR_0085|M.marinum_M QRMQRLDPSESRKAYLGAVLASILVGRMATDQHNSSPSVAKAASNAPAAP
Mb2515c|M.bovis_AF2122/97 CLQPLWRARGRLQEGLAWFAAALADHDAHPAGADPGLYARALADRALIDA
Rv2488c|M.tuberculosis_H37Rv CLQPLWRARGRLQEGLAWFAAALADHDAHPAGADPGLYARALADRALIDA
MLBr_01753|M.leprae_Br4923 SLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHA
Mvan_5653|M.vanbaalenii_PYR-1 ACADAADNDEVRVSSLVALAFAQGMVGAFEDQFASALRAVAVAERAGVPA
MUL_2555|M.ulcerans_Agy99 QSADDLDGETLTRMVNLLLAVSMFAADPALWQITDGLVDSLADRLGELSV
MAV_0578|M.avium_104 ARPETPAQAAARCAVQACLDAVAARCQLAAERARAALDSESLPDFHAMMA
MSMEG_1901|M.smegmatis_MC2_155 GR----AEQATAAYDELAERITHGAQAQRVTLGRGWLQLIRDDVDGARSN
Mflv_1352|M.gilvum_PYR-GCK GQ----PRRAAAEYDDLHERVRHGAQAQRVVMGRGWVQLMRDDVEGARSS
MAB_3361|M.abscessus_ATCC_1997 QP----ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEAD-RPANT
TH_3225|M.thermoresistible__bu PEG---SRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEV
MMAR_0085|M.marinum_M HP----PRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERDIGVAEP
Mb2515c|M.bovis_AF2122/97 VAG-----ITDRLDDAQKALAIARDIEDPALLARALTACGGVAAYNADLA
Rv2488c|M.tuberculosis_H37Rv VAG-----ITDRLDDAQKALAIARDIEDPALLARALTACGGVAAYNADLA
MLBr_01753|M.leprae_Br4923 ILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVA
Mvan_5653|M.vanbaalenii_PYR-1 LTS-------QALTTWVYVRLQAGGGLDGPALRRAVELEGADGDTPIPFR
MUL_2555|M.ulcerans_Agy99 IYR--------------------DAWADAARRGRTVTQRLKEQLDRLAEL
MAV_0578|M.avium_104 SLA-------------LIMAMGALGQVDDLTAVAEQALRRATTSFEASHM
MSMEG_1901|M.smegmatis_MC2_155 LESAIATANLGGS-------------SRITLWAMAWLARAHFVSGDWDAA
Mflv_1352|M.gilvum_PYR-GCK LESAVAAAGLGGS-------------TRITLWSHAWLARTQFSLGEWDAA
MAB_3361|M.abscessus_ATCC_1997 S-WMEQAFPIALESA-----THEVWDDDMWHHLATRAVHIAREVGALSLL
TH_3225|M.thermoresistible__bu VHWLVPAFPVLQESA-----GHELWDENLVDALSEAVVRQARDAGALAGL
MMAR_0085|M.marinum_M G-WHDLTARVCLD----------LFDQDAYNFLAARQVEDLRAAGALTML
Mb2515c|M.bovis_AF2122/97 RPWLAEAVGLARAVGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARS
Rv2488c|M.tuberculosis_H37Rv RPWLAEAVGLARAVGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARS
MLBr_01753|M.leprae_Br4923 RPYFAEAVELARTQGDKWTLSQIRLWG-VVGFCVSGDPVALRAAAEAADD
Mvan_5653|M.vanbaalenii_PYR-1 ASAMQGLALAVTG------------QLEDADRQLAEIAQRCLHRGAEHDL
MUL_2555|M.ulcerans_Agy99 EPWDVMRVALAGYYVD---------LIDDFRSVLVPLADREIEGGAATIA
MAV_0578|M.avium_104 RFWFGAVYGRACRLTG---------RIDEFVSTARRLADSARDVPGLAYA
MSMEG_1901|M.smegmatis_MC2_155 LATVVSGRDLAASSGITITTPLLEW------------IAAQISALRGD-W
Mflv_1352|M.gilvum_PYR-GCK LASVAHGRRLAETSGIVLVTPLLEW------------TAGQIAALRGD-W
MAB_3361|M.abscessus_ATCC_1997 PAALIYRAGMHVHAGELDAAAELVQ------------EADAISAATGH-A
TH_3225|M.thermoresistible__bu PQALVYRAGVHLLFGEFGLADTLLT------------EAESITAATDHRG
MMAR_0085|M.marinum_M PVALVTFAGVCVSAGNFGQADALLD------------ESAAIIAATGA-P
Mb2515c|M.bovis_AF2122/97 LADEIGDAFLSRSCRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVS
Rv2488c|M.tuberculosis_H37Rv LADEIGDAFLSRSCRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVS
MLBr_01753|M.leprae_Br4923 LAQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVT
Mvan_5653|M.vanbaalenii_PYR-1 MAVTGYRTLIAIWRGRFDDAGRLAAD-----------LLERARQVGGSMA
MUL_2555|M.ulcerans_Agy99 LATLALVAAYQLASGQWAEAVDTSQR---------GVALCSQHHYELFGY
MAV_0578|M.avium_104 NLALLLGN-AELARGAAAEAARLVQEA---------LAGAQIHEVTSGLR
MSMEG_1901|M.smegmatis_MC2_155 ETAHAAVQAADRVTQDYEMMRIPTILARAQVAEAEADYPKVRRVLEPLAA
Mflv_1352|M.gilvum_PYR-GCK ETAHAAAHAAAGG-GEYAMMRIPALLVRAQIAEAQADYATVRRVLEPLTT
MAB_3361|M.abscessus_ATCC_1997 PIRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLN
TH_3225|M.thermoresistible__bu PVRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLY
MMAR_0085|M.marinum_M PRPAIKTYLAAYRGQEQICREGVQQTVDSAASRGEGYDVSVAMYAAAILH
Mb2515c|M.bovis_AF2122/97 SCAGQACLAHALAHRGDTEAAAAAQASIDTAVGLSPVLSGSACSALVFAT
Rv2488c|M.tuberculosis_H37Rv SCAGQACLAHALAHRGDTEAAAAAQASIDTAVGLSPVLSGSACSALVFAT
MLBr_01753|M.leprae_Br4923 RTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAA
Mvan_5653|M.vanbaalenii_PYR-1 LAMSICAAAAAYRGEETQAREFARQALEQGAGHVP--LTAWARATLAFLE
MUL_2555|M.ulcerans_Agy99 QLRGYLGVISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCS
MAV_0578|M.avium_104 PASYFALAEAHGRLGHPAQANEAIAGARSCVPPDFLFMHTGLALATGWAL
MSMEG_1901|M.smegmatis_MC2_155 LAARAPGTVLTEPGYWPWPD-----VLANALVIDGALDEADEFLRPHEEV
Mflv_1352|M.gilvum_PYR-GCK LAP---GTSLQAG------------VLA---------------------V
MAB_3361|M.abscessus_ATCC_1997 NSLGRYELAFMAARRACEHE-----DLGLYSWCLIELIEAAVRCGEHDTA
TH_3225|M.thermoresistible__bu NGIGRYREALAAARTTCEYE-----DLGFYSWCLHELVEAAARVGETDTA
MMAR_0085|M.marinum_M NGLGQYQEAFNAAASGARYD-----DVGMCGYLLGELIEAAVRCKEHNAA
Mb2515c|M.bovis_AF2122/97 LAAGDVAAAEHARESATRFF-----GASAAAIINDPTSSAQISCARGDLN
Rv2488c|M.tuberculosis_H37Rv LAAGDVAAAEHARESATRFF-----GASAAAIINDPTSSAQISCARGDLN
MLBr_01753|M.leprae_Br4923 LAMGDVAAAVEASEACRPHL-----GADHGLVAIHLELMAAVALARGDVI
Mvan_5653|M.vanbaalenii_PYR-1 VSLGEHHRAVEAAEPLMALYRPFSGTEVITGSFLPDAAEALIALGRHDDA
MUL_2555|M.ulcerans_Agy99 FAEGDYESAYLQATAITAPG-EFPPLALHATRTLFDLVEAAVHTDRLNEA
MAV_0578|M.avium_104 AAGGQLREAVATAQAAARLAR---------DRGQPTHELACIQAAAQWGD
.
MSMEG_1901|M.smegmatis_MC2_155 ARERG---HRSAMARLGYARGRLLGARGELS-------AARARFEESLAL
Mflv_1352|M.gilvum_PYR-GCK GRRPG---QRDGAHR-----------------------------------
MAB_3361|M.abscessus_ATCC_1997 VKAFGQLEERALAAQSDWSQGMVARSRALITVG----HDAEPHYREAIQR
TH_3225|M.thermoresistible__bu HRALGDIEERAGASGTPWGLGALAGARALLADG----DEADRLFREALDH
MMAR_0085|M.marinum_M TEALGRLLKRTKASGTPTALGIGASATALVSDG----SIADAAYREAITH
Mb2515c|M.bovis_AF2122/97 AAHRLADGAASITRGVHRARALTTRCRIEIAQGD--RHRAERDAHDALGV
Rv2488c|M.tuberculosis_H37Rv AAHRLADGAASITRGVHRARALTTRCRIEIAQGD--RHRAERDAHDALGV
MLBr_01753|M.leprae_Br4923 VARRLADNSVSATTGWHQMAALTTRARIAMAQGE--PELARADIHAALAC
Mvan_5653|M.vanbaalenii_PYR-1 EQMVGALERNGAALDRPWMLAVGNRCRALLLVAQGDLDGALGAVERAMAE
MUL_2555|M.ulcerans_Agy99 RRHVRAAKRLQFADAPPRLAIATGAAEALCASDE----RAPALFEKVLGH
MAV_0578|M.avium_104 AAGAVRARALADALSLPLADAIACHAEALRAGNG----EALLTVAAAYRA
MSMEG_1901|M.smegmatis_MC2_155 LDGLPLRYDRARVNFAYGQTLRRAGKRRDADAVIATARDLYLSLGAHTYV
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LTNTRISAHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFA
TH_3225|M.thermoresistible__bu LSRSRVVVHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFA
MMAR_0085|M.marinum_M LRRSPVAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFA
Mb2515c|M.bovis_AF2122/97 AASIGAYLWVPDILECLASVMADAGSNREAVRLFGAADAARGRMGAVRFG
Rv2488c|M.tuberculosis_H37Rv AASIGAYLWVPDILECLASVMADAGSNREAVRLFGAADAARGRMGAVRFG
MLBr_01753|M.leprae_Br4923 GADIQASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFK
Mvan_5653|M.vanbaalenii_PYR-1 HDRLPMPFERARTQLVMGEVLRRLRRRDAAEQIVREALRQFDGLGSPVWA
MUL_2555|M.ulcerans_Agy99 PAVASFPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWT
MAV_0578|M.avium_104 IGDAAAAADAAAQASAAFVEGQQHQRGRYAAALAGELAEECGGLCTPALR
MSMEG_1901|M.smegmatis_MC2_155 ARCD---------------------------------RELKAG-GLHQLR
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ERAE---------------------------------RELRATGAKVRKR
TH_3225|M.thermoresistible__bu ERSR---------------------------------RELIAVGEKVRRQ
MMAR_0085|M.marinum_M ERAR---------------------------------RELSATGEAVYVQ
Mb2515c|M.bovis_AF2122/97 IYQAGCNSSLATLRKSMGDSEFDDAWAEGTALSIDEAIAYAQRGRGARKR
Rv2488c|M.tuberculosis_H37Rv IYQAGCNSSLATLRKSMGDSEFDDAWAEGTALSIDEAIAYAQRGRGARKR
MLBr_01753|M.leprae_Br4923 VWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKR
Mvan_5653|M.vanbaalenii_PYR-1 DRAR-------------------------------------KILARVNGS
MUL_2555|M.ulcerans_Agy99 QRAR---------------------------------NELRAAGTAVRHS
MAV_0578|M.avium_104 TPAG----------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 GSRDSVELTPQEDAVTALVAQGLSNREVAAELYVSPKTVQYHLTRVYAKL
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 SASSEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKR
TH_3225|M.thermoresistible__bu PLTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKL
MMAR_0085|M.marinum_M PTGITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKL
Mb2515c|M.bovis_AF2122/97 PTSGWGALTPTELEVALLVGEGLSNKEIGVRLFISPRTVHSHLTHVYTKL
Rv2488c|M.tuberculosis_H37Rv PTSGWGALTPTELEVALLVGEGLSNKEIGVRLFISPRTVHSHLTHVYTKL
MLBr_01753|M.leprae_Br4923 PTTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKL
Mvan_5653|M.vanbaalenii_PYR-1 GRSGSVVLTDSELRIAEHVASGMSNKEVADALYVSVKTVETNLTRVYRKL
MUL_2555|M.ulcerans_Agy99 AAVGPAPLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKL
MAV_0578|M.avium_104 -----LKLSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRV
MSMEG_1901|M.smegmatis_MC2_155 GVRSRAELAALRR------------
Mflv_1352|M.gilvum_PYR-GCK -------------------------
MAB_3361|M.abscessus_ATCC_1997 GITSRRQLRSGR-------------
TH_3225|M.thermoresistible__bu GITSRRQLRAAPRVTATW-------
MMAR_0085|M.marinum_M GVTSRRELRAILMESP---------
Mb2515c|M.bovis_AF2122/97 GLSSRLQLAQQAARRGESERGPSRP
Rv2488c|M.tuberculosis_H37Rv GLSSRLQLAQQAARRGESERGPSRP
MLBr_01753|M.leprae_Br4923 GLTSRVQLVQEAARHN---------
Mvan_5653|M.vanbaalenii_PYR-1 GIRSRAQLGTQLAQLREA-------
MUL_2555|M.ulcerans_Agy99 GVTNRAGLHDALDAIHAAPDQI---
MAV_0578|M.avium_104 GAQSRDELATIIRSRPAGRES----