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ETGGRGQPLHGRAAECDALRRSIADVQSAQSRVLVLRGEAGVGKTALLDFAAQHAKGFRITQVAGVESDM ELAYAGLQQLCAPLMNNLDDLPEPQRDALAVAFGLGVGQTPDRFLVGLAVLSLMAAAADEKPLLCIVDDA QWLDSVSVQTLAFVARRLLAEPVGLIFAVRDHGAPALAGLPELLVDGLSDTDARELLDSVILGRLDERVR DRVVAETRGIPLALLEVPRTIPAAELAGGFSTIAGRRSAGRVEDSFTSRVRSLPDEARQLLLLAAAEPIG DAALFVRAAAHLGVAVPALAPAESAGLIEFGTRIRFHHPLVRSAAYRAASVEDRRAAHHALAEATDAVTD PDRRAWHAANAAAGPSDAVATELEASAGRAQTRGGIAAAATFLERAAVLSADLHLRGARAVAAAQAKRDA ADLQAAYELLAIAELSPLSDLQRAQIARLRAQMEFSHSRREDSGPAQLRDAAAMLLDAARRLESLDDELA LQTHLEAIAAAMYAGHLGAPDALLTTAAAAQAAVDRLASRDDPIALLLDGVAKCLTGDVGDAAVPLRKAL TAWCSAAQHGDGAVLPWIFVGYPIVQESAVDELWDDTLMERLADAMVRYTRDAGALAILPAALSCRAGAH LLSGEFGTAGNLLDEANAIAVAIADQPLRYHRLHLAAWRGSTAETIAMIDSATAMAHRNGEGRLLAVLGY FAALLYNGAGRYEEAYAAIRPACSTKNLGFGGWSLVELIEAAVHTGRREAAEEAADRLAAQAGASGTDWG LGALAGARAMLADHDTADALFTEAIERLQRTRIAVELARTHLRYGEWLRRVNRRPDARRHLGVAFDMFTR MGAAGFAERARRELTATGEKVRKQPVSSGDELTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWHLRKV FVKLGIGSRRQLRTIEWAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0321 | - | - | 100% (930) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4053 | - | 0.0 | 49.84% (925) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1691 | - | 0.0 | 49.67% (920) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 3e-14 | 26.26% (575) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 1e-63 | 30.21% (940) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0386 | - | 8e-14 | 26.19% (569) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 3e-14 | 24.94% (437) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 54.10% (891) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 0.0 | 44.18% (919) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 1e-10 | 24.49% (972) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 60.70% (916) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 1e-30 | 28.20% (617) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_1214 | - | 0.0 | 63.71% (926) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
MSMEG_0321|M.smegmatis_MC2_155 ---METGGRGQPLHGRAA--------ECDALRRSIADVQSAQSRVLVLRG
Mvan_1214|M.vanbaalenii_PYR-1 ---MANQGRGVRLRGRRE--------ECATLRALVGAADPDSGRVLVIRG
TH_3225|M.thermoresistible__bu ---MSSRDGDVVLHGRAA--------EIATLRDVMSTARAGSSRVLVLHG
MAB_3361|M.abscessus_ATCC_1997 ----------------------------------------------MLRG
MMAR_0085|M.marinum_M -------MPTVTLVGRHR--------EQQQLQQLLDAARRGESGVLVLRG
Mflv_1156|M.gilvum_PYR-GCK ---------------------------MKAVDDFLAGLQQLQPAGLLIEG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ------MIGGELLIGRDS--------ELAAIRRALNGADHHRGVVIAG--
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
Rv0386|M.tuberculosis_H37Rv GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
MSMEG_0321|M.smegmatis_MC2_155 -----EAGVGKTALLDFAAQ-----HAKGFRITQVAGVESDM-----ELA
Mvan_1214|M.vanbaalenii_PYR-1 -----EAGVGKTALLDYVHR-----QATDFQCARVAGVESDM-----ELA
TH_3225|M.thermoresistible__bu -----EAGVGKTALLGQLLG-----DAAGMRCVQVAGVESDM-----ELA
MAB_3361|M.abscessus_ATCC_1997 -----QAGVGKTALLRYVLG-----KASGQLIAQASGIQSEM-----ELA
MMAR_0085|M.marinum_M -----DAGIGKTTLLTDLVD-----NAPDLRVLRVRGAEMEM-----ELT
Mflv_1156|M.gilvum_PYR-GCK -----EAGIGKTTMLAGVVD---AARQAGFRVLSAHGDQSGS-----GLA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 -----AAGVGKTWLARAALR---RAGASGEQIKWIVGTQSAQ-----ALP
MLBr_02341|M.leprae_Br4923 ---------MTTALVCVACG----------------------------AE
Mb0393|M.bovis_AF2122/97 LRDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKAWL
Rv0386|M.tuberculosis_H37Rv LRDEGNYAG-PTINRTARLRDLAHGGQT--VLSGVTESLVIDRLPDKAWL
MSMEG_0321|M.smegmatis_MC2_155 YAGLQQLCA-PLMNNLDDLPEPQRDALA--VAFGLGVGQTPDRFLVGLAV
Mvan_1214|M.vanbaalenii_PYR-1 FAGLHQLCA-PLLTHLDELPSPQRDALS--VAFGRGVGPAPDRFLVGLAV
TH_3225|M.thermoresistible__bu YAGLHQLCA-PLLDRLDDLPSPQRDVLN--VAFGRGAGPAPGRFLVGLAV
MAB_3361|M.abscessus_ATCC_1997 FAGLQQFCA-PLTKYSGAIPDPQREALT--IAFGTRSGPPPDRFLIGLAV
MMAR_0085|M.marinum_M YSGVQQLCG-PLMSLIGQLPEPQLDALE--IALGRKRGRAPDRLLLGLAV
Mflv_1156|M.gilvum_PYR-GCK HAAIADLFAGVQTDILDGLPELQRRAADGVLRRGDGTGGPTDERVIAAAL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LGAFIGLLG-------DAMSEPLTSVRR--------------------VI
MLBr_02341|M.leprae_Br4923 LRSIAKFCDECGSPVVEAETPAEYKQVT-------------------VLF
Mb0393|M.bovis_AF2122/97 VDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRF
Rv0386|M.tuberculosis_H37Rv VDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRF
MSMEG_0321|M.smegmatis_MC2_155 LSLMAAAADEKP-----------------LLCIVDDAQWLDSVSVQTLAF
Mvan_1214|M.vanbaalenii_PYR-1 LSLMSAAARSTP-----------------LLCVVDDAQWLDQVSVQTLGF
TH_3225|M.thermoresistible__bu LNLLAAAGADQP-----------------LLCVIDDAQWLDRVSLQTLGF
MAB_3361|M.abscessus_ATCC_1997 LSLLAAAAEHQP-----------------VLCVIDDAQWLDRVSLQTLAF
MMAR_0085|M.marinum_M LTLVGEASRASP-----------------ILCVVDDAQWVDSASVQALAF
Mflv_1156|M.gilvum_PYR-GCK LGAVHGSATRTP-----------------VLVAVDDVQWLDPSSVAVLAF
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ETFVARQRRGR------------------VVVGVDDAHLLDGLSALVVHQ
MLBr_02341|M.leprae_Br4923 ADVVG-------------------------SMDIAAAVGLERLREIMTEL
Mb0393|M.bovis_AF2122/97 VGRGAQITEVHRLVTDNRLVTLTGAGG----------VGKTRLAAQLAAQ
Rv0386|M.tuberculosis_H37Rv VGRGAQITEVHRLVTDNRLVTLTGAGG----------VGKTRLAAQLAAQ
MSMEG_0321|M.smegmatis_MC2_155 VAR-RLLAEPVGLIFAVRDHGAPALAG----------LPELLVDGLSDTD
Mvan_1214|M.vanbaalenii_PYR-1 VAR-RLLAEPVVMVFAVRDN-ADVLSG----------LPEMFVTGLPDGD
TH_3225|M.thermoresistible__bu VAR-RLMAEPVAMVFALRDDIHEALVG----------VPALAVPGLADAD
MAB_3361|M.abscessus_ATCC_1997 VTR-RLGSEPVAMLFAVRDGTDSELAG----------LPELTVHGLRAAD
MMAR_0085|M.marinum_M VAR-RIHVDPVAMVFATRDRGPDALTG----------HCELSLQGLEDHD
Mflv_1156|M.gilvum_PYR-GCK VAR--RVKGRVGFVVAERPGVGPGLPAATWLQVGTGALTRLPVAPMSLGA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LAQ----SGGVRLVVTVRTGSHQPDAVT--ALWKDDLLTRLDLEPLSAAA
MLBr_02341|M.leprae_Br4923 VSR-------AAGVIERYGGTVDKFTG----------DGIMAIFGAPTAL
Mb0393|M.bovis_AF2122/97 IAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGG
Rv0386|M.tuberculosis_H37Rv IAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGG
MSMEG_0321|M.smegmatis_MC2_155 ARELLDSVILGRLDERVRDRVVAETRGIPLALLEVPR-------------
Mvan_1214|M.vanbaalenii_PYR-1 ARKLLESVVLGRIDDRVRDRILAETRGNPLALLQVPR-------------
TH_3225|M.thermoresistible__bu ARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPR-------------
MAB_3361|M.abscessus_ATCC_1997 AGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPR-------------
MMAR_0085|M.marinum_M ARLVLSTAIPGRLNDSVAETVLAEANGNPLALLELHN-------------
Mflv_1156|M.gilvum_PYR-GCK LHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALELAR-------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 TREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLS-------------
MLBr_02341|M.leprae_Br4923 EDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVG------------
Mb0393|M.bovis_AF2122/97 RPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYR
Rv0386|M.tuberculosis_H37Rv RPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYR
MSMEG_0321|M.smegmatis_MC2_155 --------------------TIPAAELAGGFSTIAGRRSAGRVEDSFTSR
Mvan_1214|M.vanbaalenii_PYR-1 --------------------NVSAAELAGGFGYTIARPSAGHIEEGFVRR
TH_3225|M.thermoresistible__bu --------------------TYAVGELAGGFVSPGAGSAPSRIEENYVHR
MAB_3361|M.abscessus_ATCC_1997 --------------------DMTAEELAGGFGWPDGGRLAGQIEQTFLRR
MMAR_0085|M.marinum_M --------------------ALIRGELAGGYGLANATRTETQIERTFVSR
Mflv_1156|M.gilvum_PYR-GCK --------------------------VADGAGSRPGQRLPESLSELVRLR
MUL_2555|M.ulcerans_Agy99 ------------------------------------------MPALSANL
MAV_0578|M.avium_104 ----------------DQMAAGRMRRVAGVWMWDGDVAVSASLSDTVGRQ
MLBr_02341|M.leprae_Br4923 --------------------LNSGQVIVGEIGSSALGYTAVGVQVGMAQR
:
Mb0393|M.bovis_AF2122/97 VPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIE
Rv0386|M.tuberculosis_H37Rv VPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIE
MSMEG_0321|M.smegmatis_MC2_155 VRSLPDEARQLLLLAAAEPIGDAALFVR----------AAAHLGVAVPAL
Mvan_1214|M.vanbaalenii_PYR-1 IRSLPVKTRRLLLVAAAEPVGDPSLFLR----------AAEKLGIAVDEL
TH_3225|M.thermoresistible__bu IRALPAQTRRLLLIAAAEPIGDSALFLR----------AAALMGIAVDAL
MAB_3361|M.abscessus_ATCC_1997 VQQLPAHTQTLLLAAATDPLGDVTLLAR----------AAQQLGIPMHAI
MMAR_0085|M.marinum_M LRALPSETKTFLLVAAAESTARPEWLWA----------AAHRLGIGPEAA
Mflv_1156|M.gilvum_PYR-GCK VDGLAEDVRDVLLVAASATSPTVDLLAK---------AVGVTPAAVTGLV
MUL_2555|M.ulcerans_Agy99 VASIDRHPERITLRCDDLQSVFAELGAG----------------------
MAV_0578|M.avium_104 LGRLTPPLALVVDTLSQCEPLPVDLLCD---------------LASREDL
MLBr_02341|M.leprae_Br4923 MESVAPPGVVMLSESTARLVEQTAVLGAP------------------QTV
: : .
Mb0393|M.bovis_AF2122/97 LAAARLRSMTLD----EIIDGLRDRFALLTGGARTAAHRQQTLWASVDWS
Rv0386|M.tuberculosis_H37Rv LAAARLRSMTLD----EIIDGLRDRFALLTGGARTAAHRQQTLWASVDWS
MSMEG_0321|M.smegmatis_MC2_155 APAESAGLIEFG----TRIR-FHHPLVRSAAYRAASVEDRRAAHHALAEA
Mvan_1214|M.vanbaalenii_PYR-1 APAEAAEVIEFG----SRMR-FHHPLARSATYRTADLTERREVHRVLADA
TH_3225|M.thermoresistible__bu APAEAARVIQFG----PRMR-FFHPLMRSAAYRAADPRDRRAVHRALAEA
MAB_3361|M.abscessus_ATCC_1997 APAEAADLVELS----TRVR-FRHPLVRSAVYISANPLERRRIHGVLAGA
MMAR_0085|M.marinum_M APAEAAGLIAAQ----GSVR-FRHPLIRAAVYHSSSAAERRRVHAALAAS
Mflv_1156|M.gilvum_PYR-GCK EAAEVEGIVVID----GNRIRFTHPVLANGIYAGADPQRRREVHRRLADL
MUL_2555|M.ulcerans_Agy99 -PGDRVAALPGD----RTRRRVCGPACELSGGRFRPSAR-----------
MAV_0578|M.avium_104 VAAEAMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLATR
MLBr_02341|M.leprae_Br4923 RIKGAEDAVPAR------------RLLRVAEPRQPTWFSESTLVGREWEL
:
Mb0393|M.bovis_AF2122/97 YTLLTEPERTLFRRLAVFVGCFFV-DDAQAVACSGDVQRYQVLDEITLLV
Rv0386|M.tuberculosis_H37Rv YTLLTEPERTLFRRLAVFVGCFFV-DDAQAVACSGDVQRYQVLDEITLLV
MSMEG_0321|M.smegmatis_MC2_155 TDAVTDPDRRAWHAANAAAGPSDA-VATELEASAGRAQTRGGIAAAATFL
Mvan_1214|M.vanbaalenii_PYR-1 TDPELDPDRRAWHAAIAATGPDDA-VADDLEASAWRAERRGGIAAAATFL
TH_3225|M.thermoresistible__bu TDPGADPDRRAWHAANGVTGTDDA-VAAELEKSAARAQQRGGIAATATFL
MAB_3361|M.abscessus_ATCC_1997 TDPGADPDRRAWHRAHAAAGTDEA-IAWELEQSAGRAQAKGGVLAAAAFL
MMAR_0085|M.marinum_M IAGPDDDDHRVWHRAHAAEAPDAQ-TADDLERSAERARARGGLSAAASFL
Mflv_1156|M.gilvum_PYR-GCK KT---DPELRARHLALASTVADET-TLTTLDAAADAARARGAPAAAAELL
MUL_2555|M.ulcerans_Agy99 ------PQSCPGLTEAASPGRSRG-PLHLARCAAELTIRRGDACQAIELL
MAV_0578|M.avium_104 LAQDQDADMQATVRRALLTLESDLDPQPELYLESARHAMTLLDLDLADRL
MLBr_02341|M.leprae_Br4923 ATLAAMLDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVF
: .
Mb0393|M.bovis_AF2122/97 DKSLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTAL
Rv0386|M.tuberculosis_H37Rv DKSLVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTAL
MSMEG_0321|M.smegmatis_MC2_155 ERAAVLSADLHLRGARAVAAAQAKRDAADLQAAYELLAIAELS-------
Mvan_1214|M.vanbaalenii_PYR-1 EHAAILTSEPVKRGSRAIAAAQAKRDAAAPDSASELLAIADLQ-------
TH_3225|M.thermoresistible__bu ERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERA-------
MAB_3361|M.abscessus_ATCC_1997 QRATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMT-------
MMAR_0085|M.marinum_M EHATKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAA-------
Mflv_1156|M.gilvum_PYR-GCK EWAMQLGGDSVSR---RIRAAEHHVVAGDMRRAATLLEQALVD-------
MUL_2555|M.ulcerans_Agy99 RRAGELSDRPRRREQLLASAAFVALQAAQLDEAERLLADAGLG-------
MAV_0578|M.avium_104 ANAAARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGD-------
MLBr_02341|M.leprae_Br4923 CESHATDVAFDVVAQLVRAVAQISGLDDRSARARVREQIPDAD-------
: .
Mb0393|M.bovis_AF2122/97 AARVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLL
Rv0386|M.tuberculosis_H37Rv AARVDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLL
MSMEG_0321|M.smegmatis_MC2_155 -------------PLSDLQRAQIARLRAQMEFSHSRREDSGPAQLRDAAA
Mvan_1214|M.vanbaalenii_PYR-1 -------------PLSDLQRAQVARLRAQMEFSRSRGDEPGASQISQAAA
TH_3225|M.thermoresistible__bu -------------PLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAA
MAB_3361|M.abscessus_ATCC_1997 -------------PLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAI
MMAR_0085|M.marinum_M -------------ADDELIAARCELIRAKIAFAASRG--------SDAPP
Mflv_1156|M.gilvum_PYR-GCK -------------------------LRPGVLCAIALNLLAGVRMVEDDYI
MUL_2555|M.ulcerans_Agy99 --------------------------GGASASALLISSFISLYRYGDVTA
MAV_0578|M.avium_104 -----------------------ASDRHYWATVRAANLVWMLGRPADAAL
MLBr_02341|M.leprae_Br4923 ---------------------------------------TQDLLLLDDLL
.
Mb0393|M.bovis_AF2122/97 RVWMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVD
Rv0386|M.tuberculosis_H37Rv RVWMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVD
MSMEG_0321|M.smegmatis_MC2_155 MLLDAARRLES--------------LDDELALQTHLEAIAAAMYAG-HLG
Mvan_1214|M.vanbaalenii_PYR-1 QLRSAAERLET--------------LDGELSRETYLEALAAAMYASARCG
TH_3225|M.thermoresistible__bu ALLTAAQLLQD--------------VDAPAARESYLEAFAALMYAG-RLA
MAB_3361|M.abscessus_ATCC_1997 GLVEAARCLEN--------------LDDNLARETYLDAVGAAMYGG-RLC
MMAR_0085|M.marinum_M LLLAAAQRMQR--------------LDPSESRKAYLGAVLASILVGRMAT
Mflv_1156|M.gilvum_PYR-GCK RAVELLERARA----------------DADNDAVLVTTLLSLGFCLGMTG
MUL_2555|M.ulcerans_Agy99 THRRLVERLQS---------------ADDLDGETLTRMVNLLLAVSMFAA
MAV_0578|M.avium_104 VLDGLAARPET-----------------PAQAAARCAVQACLDAVAARCQ
MLBr_02341|M.leprae_Br4923 GIADPAVELPR------------------LDPDARRRRLTALINVAQLAL
Mb0393|M.bovis_AF2122/97 AAAGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAE
Rv0386|M.tuberculosis_H37Rv AAAGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAE
MSMEG_0321|M.smegmatis_MC2_155 APDALLTTAAAAQAAVDRLASRDDPIALLLDGVAKCLTGDVGDAAVPLRK
Mvan_1214|M.vanbaalenii_PYR-1 DPGLLMSTAEGARRAVSRLDTLDHPADHLLSGLATLLVGGRREGADHLRT
TH_3225|M.thermoresistible__bu PSGALLEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRV
MAB_3361|M.abscessus_ATCC_1997 PRGGAVEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGE
MMAR_0085|M.marinum_M DQHNSSPSVAKAASNAPAAPHPPRALDVLLDGLVIRLTEGYVAAAPRLRS
Mflv_1156|M.gilvum_PYR-GCK SFTAQLATVREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLR
MUL_2555|M.ulcerans_Agy99 DPALWQITDGLVDSLADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDR
MAV_0578|M.avium_104 LAAERARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRR
MLBr_02341|M.leprae_Br4923 SRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRH
:
Mb0393|M.bovis_AF2122/97 AIDLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGD
Rv0386|M.tuberculosis_H37Rv AIDLARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGD
MSMEG_0321|M.smegmatis_MC2_155 ALTAWCSAAQHGDGAVLPWIFVGYPIVQESAVDELWDDTLMERLADAMVR
Mvan_1214|M.vanbaalenii_PYR-1 ALRMWCARAGERDGQDLRWLSLAFPIVHECCAAELYDDGLTHELADVMVR
TH_3225|M.thermoresistible__bu ALTAMCELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVR
MAB_3361|M.abscessus_ATCC_1997 ALTLIRCEADR--PANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVH
MMAR_0085|M.marinum_M AIREYLR------ERDIGVAEPGWHDLTARVCLDLFDQDAYNFLAARQVE
Mflv_1156|M.gilvum_PYR-GCK AVDLEDP-------EDNTPIPFRASAARGLSLALTGRLAEADGQLAAVAQ
MUL_2555|M.ulcerans_Agy99 ----------------LAELEPWDVMRVALAGYYVDLIDDFRSVLVPLAD
MAV_0578|M.avium_104 ATTS----------FEASHMRFWFGAVYGRACRLTGRIDEFVSTARRLAD
MLBr_02341|M.leprae_Br4923 VVG-----------AQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELIT
Mb0393|M.bovis_AF2122/97 HSNALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQG
Rv0386|M.tuberculosis_H37Rv HSNALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQG
MSMEG_0321|M.smegmatis_MC2_155 YTRDAGALAILPAALSCRAGAHLLSGEFGTAGNLLDEANAIAVAIADQ-P
Mvan_1214|M.vanbaalenii_PYR-1 YARDVGALAVLPAALSYRAGIHVIAGEFNTAATLLDESDAISAAINYR-P
TH_3225|M.thermoresistible__bu QARDAGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGP
MAB_3361|M.abscessus_ATCC_1997 IAREVGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGHA-P
MMAR_0085|M.marinum_M DLRAAGALTMLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATGAP-P
Mflv_1156|M.gilvum_PYR-GCK RSAQRGAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMV
MUL_2555|M.ulcerans_Agy99 REIEGGAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELF
MAV_0578|M.avium_104 SARDVPGLAYANLALLLGN-AELARGAAAEAARLVQEALAGAQIHEVTSG
MLBr_02341|M.leprae_Br4923 ERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIA
. .
Mb0393|M.bovis_AF2122/97 LAFAL---AYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAG
Rv0386|M.tuberculosis_H37Rv LAFAL---AYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAG
MSMEG_0321|M.smegmatis_MC2_155 LRYHR---LHLAAWRGSTAETIAMIDSATAMAHRNGEGR-----------
Mvan_1214|M.vanbaalenii_PYR-1 VKYHR---LHLAAWRGVPADALALIEPATKEATAKGEGR-----------
TH_3225|M.thermoresistible__bu VRYHR---LIIAAWRGDAVEAARLIEAAAADGEARGEGR-----------
MAB_3361|M.abscessus_ATCC_1997 IRYHS---LILAAWRGSEPTAIRLIDEAMRDGAARGEGR-----------
MMAR_0085|M.marinum_M RPAIK---TYLAAYRGQEQICREGVQQTVDSAASRGEGY-----------
Mflv_1156|M.gilvum_PYR-GCK IAFSIC--AAVAAYRGREDQARDQAAGALAQGGDYVALT-----------
MUL_2555|M.ulcerans_Agy99 GYQLRGYLGVISACRGDVVRARELAAQVRVWAEPRRVGF-----------
MAV_0578|M.avium_104 LRPAS--YFALAEAHGRLGHPAQANEAIAGARSCVPPDF-----------
MLBr_02341|M.leprae_Br4923 ARIDR-----------LSPPAKQLLVAAAVIGFRFGSDL-----------
Mb0393|M.bovis_AF2122/97 DVQTAQHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDD
Rv0386|M.tuberculosis_H37Rv DVQTAQHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDD
MSMEG_0321|M.smegmatis_MC2_155 ------------------LLAVLGYFAALLYNGAGRYEEAYAAIRPACST
Mvan_1214|M.vanbaalenii_PYR-1 ------------------LLGLAGYASALLYNGLGRYQEAFQAARRTCEE
TH_3225|M.thermoresistible__bu ------------------LMGLTGYAAALLYNGIGRYREALAAARTTCEY
MAB_3361|M.abscessus_ATCC_1997 ------------------LLGAMGYAAGVLNNSLGRYELAFMAARRACEH
MMAR_0085|M.marinum_M ------------------DVSVAMYAAAILHNGLGQYQEAFNAAASGARY
Mflv_1156|M.gilvum_PYR-GCK --------------------VWASATLAFLEVSRGNYEQALEAAEPLVDL
MUL_2555|M.ulcerans_Agy99 ------------------LTGAVAQIAILCSFAEGDYESAYLQATAITAP
MAV_0578|M.avium_104 ----------------LFMHTGLALATGWALAAGGQLREAVATAQAAARL
MLBr_02341|M.leprae_Br4923 -------------------LASLGIDLSVDELIDANLVDQVRFTAPVEYA
.
Mb0393|M.bovis_AF2122/97 AVQS-----MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESG
Rv0386|M.tuberculosis_H37Rv AVQS-----MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESG
MSMEG_0321|M.smegmatis_MC2_155 KNLG-----FGGWSLVELIEAAVHTGRREAAEEAADRLAAQAGASGTDWG
Mvan_1214|M.vanbaalenii_PYR-1 VDLG-----FHGWCLVELIESAARIDELDEAASALHRLEERAADTGTEWG
TH_3225|M.thermoresistible__bu EDLG-----FYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWG
MAB_3361|M.abscessus_ATCC_1997 EDLG-----LYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWS
MMAR_0085|M.marinum_M DDVG-----MCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTA
Mflv_1156|M.gilvum_PYR-GCK YRDFPGTELMSACFMPDAIESLIAVGRLDEAEPLIAAFERNGAELDRPWQ
MUL_2555|M.ulcerans_Agy99 GEFPP-LALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRL
MAV_0578|M.avium_104 ARDR-----------GQPTHELACIQAAAQWGDAAGAVRARALADALSLP
MLBr_02341|M.leprae_Br4923 FRHP-------------LIRTVAYESQLKSDRARLHRRLAAAIEARAPHS
Mb0393|M.bovis_AF2122/97 AHLDLPDVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAI
Rv0386|M.tuberculosis_H37Rv AHLDLPDVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAI
MSMEG_0321|M.smegmatis_MC2_155 LGALAGARAMLADHD----TADALFTEAIERLQRTRIAVELARTHLRYGE
Mvan_1214|M.vanbaalenii_PYR-1 LGALAGAKALLADDE----YADALFTEAIARLDQTRVAVHAARTRLCYGE
TH_3225|M.thermoresistible__bu LGALAGARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLTYGE
MAB_3361|M.abscessus_ATCC_1997 QGMVARSRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGE
MMAR_0085|M.marinum_M LGIGASATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLTYGE
Mflv_1156|M.gilvum_PYR-GCK LAIGNRCRAMLLSATGDLDGALAAAERAMAEHARLPMPFERARSALTLGE
MUL_2555|M.ulcerans_Agy99 AIATGAAEALCASDE----RAPALFEKVLGHPAVASFPFEHARIRLAYGM
MAV_0578|M.avium_104 LADAIACHAEALRAG----NGEALLTVAAAYRAIGDAAAAADAAAQASAA
MLBr_02341|M.leprae_Br4923 VDQHAVLIAEHLEAAG--------------------------DLHAAYGW
.
Mb0393|M.bovis_AF2122/97 YRSDYVQSVTALRDAMGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRP
Rv0386|M.tuberculosis_H37Rv YRSDYVQSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRP
MSMEG_0321|M.smegmatis_MC2_155 WLRRVNR-RPDARRHLGVAFDMFTRMGAAGFAERARRELTATGEKVRKQP
Mvan_1214|M.vanbaalenii_PYR-1 WLRRRNR-RPDARTQLGDAHEMFTRFGAQAYAERARRELTAAGEKVRTQP
TH_3225|M.thermoresistible__bu WLRREHR-RGEARRELNEAHGMFTRMGAQGFAERSRRELIAVGEKVRRQP
MAB_3361|M.abscessus_ATCC_1997 WLRRCNR-RSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRKRS
MMAR_0085|M.marinum_M WLRRERR-RSEARSQLRIAYDMFAQMGAAGFAERARRELSATGEAVYVQP
Mflv_1156|M.gilvum_PYR-GCK VLRRLRR--RDAAAAVRDALAQFEELGVPLWVARARIALSGLAVSG----
MUL_2555|M.ulcerans_Agy99 RLRRLRR-YRNARVVLRAAAEIFAGLGAEPWTQRARNELRAAGTAVRHSA
MAV_0578|M.avium_104 FVEGQQH-----------------QRGRYAAALAGELAEECGGLCTPALR
MLBr_02341|M.leprae_Br4923 HMRAAAWATNQDVRAARVSWEHATKIADALTAEDPHRAAMCIAPRTRLCG
.
Mb0393|M.bovis_AF2122/97 ATGWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLG
Rv0386|M.tuberculosis_H37Rv ATGWESLTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLG
MSMEG_0321|M.smegmatis_MC2_155 VSSGDELTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWHLRKVFVKLG
Mvan_1214|M.vanbaalenii_PYR-1 DGTGGELTAQETQIARLAAEGFTNQEIGAQLFISAHTAEWHLRKVFVKLG
TH_3225|M.thermoresistible__bu LTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLG
MAB_3361|M.abscessus_ATCC_1997 ASSEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRG
MMAR_0085|M.marinum_M TGITVDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLG
Mflv_1156|M.gilvum_PYR-GCK SAVGSELTDSERRIAELAASGMSNRDVAETLFVSVKTIETNLSRVYRKLG
MUL_2555|M.ulcerans_Agy99 AVGPAPLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLG
MAV_0578|M.avium_104 TPAGLKLSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVG
MLBr_02341|M.leprae_Br4923 IAWRGRFNSS----SGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDRL
:. : . :: * : :
Mb0393|M.bovis_AF2122/97 FTSRLQLAQAAARRT------
Rv0386|M.tuberculosis_H37Rv FTSRLQLAQAAARRT------
MSMEG_0321|M.smegmatis_MC2_155 IGSRRQLRTIEWAG-------
Mvan_1214|M.vanbaalenii_PYR-1 ITSRRQLRSISWAS-------
TH_3225|M.thermoresistible__bu ITSRRQLRAAPRVTATW----
MAB_3361|M.abscessus_ATCC_1997 ITSRRQLRSGR----------
MMAR_0085|M.marinum_M VTSRRELRAILMESP------
Mflv_1156|M.gilvum_PYR-GCK IRSRAQLGRMLR---------
MUL_2555|M.ulcerans_Agy99 VTNRAGLHDALDAIHAAPDQI
MAV_0578|M.avium_104 AQSRDELATIIRSRPAGRES-
MLBr_02341|M.leprae_Br4923 H--------------------