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DEQMTQRGERHLIGRATERGALRQVCADLRSGSGRALVLRGEPGVGKTALLDWLFDEQTGSAGVQVVRVR GVASDMDLTYAALQQVCAPLLDHLKRLPDLQQQALTVAFGRGPGPQPDRFLVGLAVVELMAAAAAAKPVL CIVDDAQWVDDASLQALVFVARRLPDAPLALLFGVRCGTALPGLPELAVGRLNDCEAGELFDALLPGPID PRVRDRIVGETRGNPRALHALPATFAAAEVAGGFTNPRMRLALTNPGVTSEFPEPTRRLLLVAAAEPTGD PLLLARAADILGIGLRALAPAETAGLVEMGARVWFREPYLRTVIYRTARLDERRTVHRALAQATDATLDP ARRAWHAANAANGPDETVATQLQEAVVSARDTGGVVAAAAFWERATALTADPARRAARALAAAEAKYVAG EHSTSLDLLGIAEAGPLGAAQRALATRLRLLLDDGPASALLDVAHGLGALDTRAACEVHRDALAAAISAG RSGEAHILKEAAESARSATARDEAGDLLLDALATRIACGPSAIGPLRRALSVSPASLWPTVPMLLEAAVA DCWDDDAWHTASTALLQDVRHSGALALLPEALAFRAGLHLQCGEFSSAAELLAEASDRGAHAAMLAAWRG DVAETTRLTEGLGAGRAVGVAGHAVAVLNNGLGHYEQAFAAAQQACEYEDLGFHGGTLVELIEAGTRCGQ RDSATEALYLLEERTTQAGTAWAAAALAGGRALLSSGRRADGLHRESIEHYERTRLTVQAARARLRYGEW LRRANRRPDAVRELTAAHEVFVRIGAQAFAERARRELVAAGPTARRVPGRSGEQLTAQETQVAGLAARGL TNQEIAAQLFISPHTVEWHLRKVFVKLGITSRRQLRTHGPRTTGFQGSAFEVERRA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1691 | - | - | 100% (897) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 0.0 | 49.67% (920) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3290 | - | e-177 | 45.51% (903) | regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 3e-15 | 26.52% (577) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4504 | - | 5e-54 | 29.49% (919) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0386 | - | 1e-14 | 26.34% (577) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 6e-10 | 26.02% (465) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 0.0 | 48.43% (890) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 1e-156 | 40.18% (911) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 3e-14 | 24.84% (946) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3225 | - | 0.0 | 49.84% (933) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 3e-30 | 27.19% (526) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | 0.0 | 49.08% (925) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
TH_3225|M.thermoresistible__bu -------------MSSRD-----GDVVLHGRAAEIATLRDVMSTARAGSS
Mvan_5002|M.vanbaalenii_PYR-1 ---------MDTRLDTRHPAGHRARPPLRGRGHECRELQNLIAAVRTGAS
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_1691|M.smegmatis_MC2_155 ---------MDEQMTQRG------ERHLIGRATERGALRQVCADLRSGSG
MMAR_0085|M.marinum_M ----------------------MPTVTLVGRHREQQQLQQLLDAARRGES
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK -------------MRAALPAAMMNAMSDASPQAADDPQVAGFLCTATSAP
MAV_0578|M.avium_104 ---------------------MIGGELLIGRDSELAAIRRALN--GADHH
MLBr_02341|M.leprae_Br4923 -------------------------------------MTTALVCVACGAE
Mb0393|M.bovis_AF2122/97 GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
Rv0386|M.tuberculosis_H37Rv GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
TH_3225|M.thermoresistible__bu RVLVLHGEAGVGKTALLGQLLGDAAG---MRCVQVAGVESDM-----ELA
Mvan_5002|M.vanbaalenii_PYR-1 RSLVLRGEAGIGKTALLDHVVAQAEG---FRTTYVAGVESDM-----ELA
MAB_3361|M.abscessus_ATCC_1997 ---MLRGQAGVGKTALLRYVLGKASG---QLIAQASGIQSEM-----ELA
MSMEG_1691|M.smegmatis_MC2_155 RALVLRGEPGVGKTALLDWLFDEQTGSAGVQVVRVRGVASDM-----DLT
MMAR_0085|M.marinum_M GVLVLRGDAGIGKTTLLTDLVDNAPD---LRVLRVRGAEMEM-----ELT
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK TGLIIEGDAGIGKTTLWLSLLQTARMRG-FQVLTARVGQAES-----VMA
MAV_0578|M.avium_104 RGVVIAGAAGVGKTWLARAALRRAGASG-EQIKWIVGTQSAQ-----ALP
MLBr_02341|M.leprae_Br4923 LRSIAKFCDECGSPVVEAETPAEYKQVT--------------------VL
Mb0393|M.bovis_AF2122/97 LRDEGNYAGPT-INRTARLRDLAHGGQTVLSGVT--ESLVIDRLPDKAWL
Rv0386|M.tuberculosis_H37Rv LRDEGNYAGPT-INRTARLRDLAHGGQTVLSGVT--ESLVIDRLPDKAWL
TH_3225|M.thermoresistible__bu YAGLHQLCAPL-LDRLDDLPSPQRDVLNVAFGRG--AGPAPGRFLVGLAV
Mvan_5002|M.vanbaalenii_PYR-1 FAGLHQLCAPL-LTHLDELPDPQRDALTVAFGQG--AGATPDRFLVGLAV
MAB_3361|M.abscessus_ATCC_1997 FAGLQQFCAPL-TKYSGAIPDPQREALTIAFGTR--SGPPPDRFLIGLAV
MSMEG_1691|M.smegmatis_MC2_155 YAALQQVCAPL-LDHLKRLPDLQQQALTVAFGRG--PGPQPDRFLVGLAV
MMAR_0085|M.marinum_M YSGVQQLCGPL-MSLIGQLPEPQLDALEIALGRK--RGRAPDRLLLGLAV
MUL_2555|M.ulcerans_Agy99 -----------------------MPALSANLVAS--IDRHPERITLRCDD
Mflv_4504|M.gilvum_PYR-GCK FAALADLLGAVSDEHFAALPPLQRLALDRVLLRAGADGPATDQRVVAAGF
MAV_0578|M.avium_104 LGAFIGLLGDAMSEPLTSVRRVIETFVARQRRGRVVVGVDDAHLLDGLSA
MLBr_02341|M.leprae_Br4923 FADVVGSMDIAAAVGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIM
. :
Mb0393|M.bovis_AF2122/97 VDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRF
Rv0386|M.tuberculosis_H37Rv VDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRF
TH_3225|M.thermoresistible__bu LNLLAAAGADQP-----------------LLCVIDDAQWLDRVSLQTLGF
Mvan_5002|M.vanbaalenii_PYR-1 LSLMAAASTGGP-----------------LLCVIDDAQWLDQVSVQTLAF
MAB_3361|M.abscessus_ATCC_1997 LSLLAAAAEHQP-----------------VLCVIDDAQWLDRVSLQTLAF
MSMEG_1691|M.smegmatis_MC2_155 VELMAAAAAAKP-----------------VLCIVDDAQWVDDASLQALVF
MMAR_0085|M.marinum_M LTLVGEASRASP-----------------ILCVVDDAQWVDSASVQALAF
MUL_2555|M.ulcerans_Agy99 LQSVFAELGAGP--------------------------------------
Mflv_4504|M.gilvum_PYR-GCK VSLLHILAADAP-----------------VLIAIDDVQWLDASSRTAIEF
MAV_0578|M.avium_104 LVVHQLAQSGGVR------------------------------------L
MLBr_02341|M.leprae_Br4923 AIFGAPT-------------------------------------------
Mb0393|M.bovis_AF2122/97 VGRGAQITEVHRLVTDNRLVTLTGA--------GGVGKTRLAAQLAAQIA
Rv0386|M.tuberculosis_H37Rv VGRGAQITEVHRLVTDNRLVTLTGA--------GGVGKTRLAAQLAAQIA
TH_3225|M.thermoresistible__bu VAR-RLMAEPVAMVFALRDDIHEAL--------VGVPALAVPGLADADAR
Mvan_5002|M.vanbaalenii_PYR-1 VAR-RLLAEPIAMVFAARDTGAEAL--------SGLPELAVPGLSDGEAR
MAB_3361|M.abscessus_ATCC_1997 VTR-RLGSEPVAMLFAVRDGTDSEL--------AGLPELTVHGLRAADAG
MSMEG_1691|M.smegmatis_MC2_155 VAR-RLPDAPLALLFGVRCG--TAL--------PGLPELAVGRLNDCEAG
MMAR_0085|M.marinum_M VAR-RIHVDPVAMVFATRDRGPDAL--------TGHCELSLQGLEDHDAR
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK AVRRLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPPMDAGRLH
MAV_0578|M.avium_104 VVTVRTGSHQPDAVTALWKDDLLTR-------------LDLEPLSAAATR
MLBr_02341|M.leprae_Br4923 ------------------------------------------ALEDHALR
Mb0393|M.bovis_AF2122/97 GEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGGRP
Rv0386|M.tuberculosis_H37Rv GEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGGRP
TH_3225|M.thermoresistible__bu TLLEHMFPGAIDANVRDRLVAESRGNPLALLEVP----RTYAVGELAGGF
Mvan_5002|M.vanbaalenii_PYR-1 DLLDSVVVGRLDDRVRDRIIAETRGNPLALLDLP----HNHVGTELPGSA
MAB_3361|M.abscessus_ATCC_1997 TLLDSVIPGLLDERVRDRIVAETQGNPLALLELP----RDMTAEELAGGF
MSMEG_1691|M.smegmatis_MC2_155 ELFDALLPGPIDPRVRDRIVGETRGNPRALHALP----ATFAAAEVAGGF
MMAR_0085|M.marinum_M LVLSTAIPGRLNDSVAETVLAEANGNPLALLELH----NALIRGELAGGY
MUL_2555|M.ulcerans_Agy99 ---GDRVAALPGDRTRRRVCG--------------------PACELSGG-
Mflv_4504|M.gilvum_PYR-GCK ALISHRLGRTLTRPVVLRIAEMSGGNPFYALELA-------HTHVNSGDS
MAV_0578|M.avium_104 EVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLSDQMAAGRMRRVAGVW
MLBr_02341|M.leprae_Br4923 ACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLN-------SGQVIVGEI
. *
Mb0393|M.bovis_AF2122/97 ALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVP
Rv0386|M.tuberculosis_H37Rv ALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVP
TH_3225|M.thermoresistible__bu VSPGAGSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGDSALFLRAAA
Mvan_5002|M.vanbaalenii_PYR-1 ATPGSRPLARRLEQSYARRIKALPPQTQLLLLAAAAEPVGDAAVLIRAAA
MAB_3361|M.abscessus_ATCC_1997 GWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTLLARAAQ
MSMEG_1691|M.smegmatis_MC2_155 TNP-----RMRLALTNPGVTSEFPEPTRRLLLVAAAEPTGDPLLLARAAD
MMAR_0085|M.marinum_M GLANATRTETQIERTFVSRLRALPSETKTFLLVAAAESTARPEWLWAAAH
MUL_2555|M.ulcerans_Agy99 ----------------RFRPSARPQSCPGLTEAASPGRSRGPLHLARCAA
Mflv_4504|M.gilvum_PYR-GCK PPAAEPPLPATLADVVRRRVGLLDDATRTLLLGVACVADPTVELLARAHG
MAV_0578|M.avium_104 MWDGDVAVSASLSDTVGRQLGRLTPPLALVVDTLSQCEPLPVDLLCDLAS
MLBr_02341|M.leprae_Br4923 GSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVLGAPQT
.
Mb0393|M.bovis_AF2122/97 SLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELA
Rv0386|M.tuberculosis_H37Rv SLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELA
TH_3225|M.thermoresistible__bu LMGIAVDALAP----------------AEAARVIQFGPRMR---------
Mvan_5002|M.vanbaalenii_PYR-1 QLGIAVDMLTP----------------AEAAGVIELGTRVR---------
MAB_3361|M.abscessus_ATCC_1997 QLGIPMHAIAP----------------AEAADLVELSTRVR---------
MSMEG_1691|M.smegmatis_MC2_155 ILGIGLRALAP----------------AETAGLVEMGARVW---------
MMAR_0085|M.marinum_M RLGIGPEAAAP----------------AEAAGLIAAQGSVR---------
MUL_2555|M.ulcerans_Agy99 ELTIRRGDACQ---------------------------------------
Mflv_4504|M.gilvum_PYR-GCK ASTDEITAGLER---------------AEAAGIVVLEGNRVR--------
MAV_0578|M.avium_104 REDLVAAEAMG----------------LVTVERTPRALMAR---------
MLBr_02341|M.leprae_Br4923 VRIKGAEDAVP---------------------------------------
Mb0393|M.bovis_AF2122/97 AARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTE
Rv0386|M.tuberculosis_H37Rv AARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTE
TH_3225|M.thermoresistible__bu ---------------FFHPLMRSAAYRAADPRDRRAVHRALAEATDPGAD
Mvan_5002|M.vanbaalenii_PYR-1 ---------------FRHPLVRSAAYQAADLADRRTVHRALAEATDSATD
MAB_3361|M.abscessus_ATCC_1997 ---------------FRHPLVRSAVYISANPLERRRIHGVLAGATDPGAD
MSMEG_1691|M.smegmatis_MC2_155 ---------------FREPYLRTVIYRTARLDERRTVHRALAQATDATLD
MMAR_0085|M.marinum_M ---------------FRHPLIRAAVYHSSSAAERRRVHAALAASIAGPDD
MUL_2555|M.ulcerans_Agy99 ----------------AIELLRRAGELSDRPRRREQLLASAAFVALQAAQ
Mflv_4504|M.gilvum_PYR-GCK ---------------FTHPLLAGGVYTDAGPTARRAMHRAIASVES---H
MAV_0578|M.avium_104 ---------------LAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQD
MLBr_02341|M.leprae_Br4923 ----------------ARRLLRVAEPRQPTWFSESTLVGREWELATLAAM
:
Mb0393|M.bovis_AF2122/97 PERTLFRR--LAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLV
Rv0386|M.tuberculosis_H37Rv PERTLFRR--LAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLV
TH_3225|M.thermoresistible__bu PDRRAWHA--ANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVV
Mvan_5002|M.vanbaalenii_PYR-1 PDRRAWHA--ANAATGPDDAVAAELEASAARAQARGGVAAAAAFLERAAA
MAB_3361|M.abscessus_ATCC_1997 PDRRAWHR--AHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATE
MSMEG_1691|M.smegmatis_MC2_155 PARRAWHA--ANAANGPDETVATQLQEAVVSARDTGGVVAAAAFWERATA
MMAR_0085|M.marinum_M DDHRVWHR--AHAAEAPDAQTADDLERSAERARARGGLSAAASFLEHATK
MUL_2555|M.ulcerans_Agy99 LDEAERLL--ADAGLGGGASASALLISSFISLYRYGDVTATHRRLVERLQ
Mflv_4504|M.gilvum_PYR-GCK PELRARHL--ALAASSGDDEIFAALDQAADSARARGAPAAAAELMDLALG
MAV_0578|M.avium_104 ADMQATVRR-ALLTLESDLDPQPELYLESARHAMTLLDLDLADRLANAAA
MLBr_02341|M.leprae_Br4923 LDRSIGGRGSVVGLVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHAT
Mb0393|M.bovis_AF2122/97 MADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVD
Rv0386|M.tuberculosis_H37Rv MADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVD
TH_3225|M.thermoresistible__bu LTADPGLRGRRALAAAQAKRDAADSAAA--------------------HD
Mvan_5002|M.vanbaalenii_PYR-1 LTSDPALRGARALAAAQAKRDAAAPAEA--------------------QE
MAB_3361|M.abscessus_ATCC_1997 LTADPAARGRRALAAAQSKYDAAAFDAA--------------------RE
MSMEG_1691|M.smegmatis_MC2_155 LTADPARRAARALAAAEAKYVAGEHSTS--------------------LD
MMAR_0085|M.marinum_M LTPDPFVRASRALDAAMTSLEAGMPDSA--------------------TR
MUL_2555|M.ulcerans_Agy99 SADDLDGETLTRMVNLLLAVSMFAADPA----------------------
Mflv_4504|M.gilvum_PYR-GCK LGAHDPMRRLKAAENHFLAGDTAKAAAA--------------------LG
MAV_0578|M.avium_104 RAGAPGAAGVRAMNLVLLGRGEQAEEALR------------------AIT
MLBr_02341|M.leprae_Br4923 DVAFDVVAQLVRAVAQISGLDDRSARAR----------------------
Mb0393|M.bovis_AF2122/97 NPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRVWMT
Rv0386|M.tuberculosis_H37Rv NPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRVWMT
TH_3225|M.thermoresistible__bu LLAIAERAPLSALEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAALLTA
Mvan_5002|M.vanbaalenii_PYR-1 LLSTAELGRLSELQQAQAARLRAQMEFTRRRGGDTGARPLDETASQLLTA
MAB_3361|M.abscessus_ATCC_1997 LLGVADMTPLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEA
MSMEG_1691|M.smegmatis_MC2_155 LLGIAEAGPLGAAQRALATRLRLLLD--------------DGPASALLDV
MMAR_0085|M.marinum_M LVASAAAAADDELIAARCELIRAKIAFAASRG--------SDAPPLLLAA
MUL_2555|M.ulcerans_Agy99 ---------LWQITDGLVDSLADRLG------------------------
Mflv_4504|M.gilvum_PYR-GCK EVGSIEPPILRAMATSLLATVRMYDN---------------EHRQAVDLL
MAV_0578|M.avium_104 DGADGDASDRHYWATVRAANLVWMLG------------RPADAALVLDGL
MLBr_02341|M.leprae_Br4923 -----VREQIPDADTQDLLLLDDLLG--------------------IADP
:
Mb0393|M.bovis_AF2122/97 RGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAAGM
Rv0386|M.tuberculosis_H37Rv RGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAAGM
TH_3225|M.thermoresistible__bu AQLLQD----VDAPAARESYLEAFAALMYAGRLA-----------PSGAL
Mvan_5002|M.vanbaalenii_PYR-1 AASFEQ----LDGYVSREAYLEALAAAMFAGRLG-----------DPGAV
MAB_3361|M.abscessus_ATCC_1997 ARCLEN----LDDNLARETYLDAVGAAMYGGRLC-----------PRGGA
MSMEG_1691|M.smegmatis_MC2_155 AHGLGA----LDTRAACEVHRDALAAAISAGRSG-----------EAHIL
MMAR_0085|M.marinum_M AQRMQR----LDPSESRKAYLGAVLASILVGRMATD---------QHNSS
MUL_2555|M.ulcerans_Agy99 --------------ELSVIYRDAWADAARRGRTVT---------------
Mflv_4504|M.gilvum_PYR-GCK RSALDD------AADNVPVQVQVLLRLSFALNSIG----------ELDDA
MAV_0578|M.avium_104 AARPET-----PAQAAARCAVQACLDAVAARCQLA------------AER
MLBr_02341|M.leprae_Br4923 AVELPR-----LDPDARRRRLTALINVAQLALSRP--------------A
Mb0393|M.bovis_AF2122/97 EQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLA
Rv0386|M.tuberculosis_H37Rv EQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLA
TH_3225|M.thermoresistible__bu LEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAM
Mvan_5002|M.vanbaalenii_PYR-1 PRIAAAASAALDRLPESARPVDALLRGIVARITGGVSAGAAPLRLAMDLM
MAB_3361|M.abscessus_ATCC_1997 VEVAEPARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLI
MSMEG_1691|M.smegmatis_MC2_155 KEAAESARSATARDEA----GDLLLDALATRIACGPSAIG-PLRRALSVS
MMAR_0085|M.marinum_M PSVAKAASNAPAAPHP-PRALDVLLDGLVIRLTEGYVAAAPRLRSAIREY
MUL_2555|M.ulcerans_Agy99 QRLKEQLDR-----------------------------------------
Mflv_4504|M.gilvum_PYR-GCK RRYARDAVKLAEELGFPGATSAALAWAVHVDFQCGRGLDETALARAMKLY
MAV_0578|M.avium_104 ARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSF
MLBr_02341|M.leprae_Br4923 VFVVEDVHWIDEVSDS----------------------------------
Mb0393|M.bovis_AF2122/97 RAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNAL
Rv0386|M.tuberculosis_H37Rv RAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNAL
TH_3225|M.thermoresistible__bu CELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDA
Mvan_5002|M.vanbaalenii_PYR-1 QEQARNNDHRVARWMVPAFPIMQETAALELWDETVVHHLASVVVRRARDA
MAB_3361|M.abscessus_ATCC_1997 RCEADRPAN--TSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREV
MSMEG_1691|M.smegmatis_MC2_155 -----------PASLWPTVPMLLEAAVADCWDDDAWHTASTALLQDVRHS
MMAR_0085|M.marinum_M LRERD------IGVAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAA
MUL_2555|M.ulcerans_Agy99 -----------LAELEPWDVMRVALAGYYVDLIDDFRSVLVPLADREIEG
Mflv_4504|M.gilvum_PYR-GCK DSTFD-------VPIIFRAPFVHALAMSWTGRLEQAHQELTAVRGVCLER
MAV_0578|M.avium_104 EAS----------HMRFWFGAVYGRACRLTGRIDEFVSTARRLADSARDV
MLBr_02341|M.leprae_Br4923 ------------MLADFLAVIPQTRSMALVTYRPEYHGALRHVVGAQIIA
Mb0393|M.bovis_AF2122/97 WCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQG---LA
Rv0386|M.tuberculosis_H37Rv WCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQG---LA
TH_3225|M.thermoresistible__bu GALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGP---VR
Mvan_5002|M.vanbaalenii_PYR-1 GALEALPQVLAYRAGAHLLAGELSSAATLLEEAASITAATNNYTP---VR
MAB_3361|M.abscessus_ATCC_1997 GALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATG-HAP---IR
MSMEG_1691|M.smegmatis_MC2_155 GALALLPEALAFRAGLHLQCGEFSSAAELLAEASDR-------------G
MMAR_0085|M.marinum_M GALTMLPVALVTFAGVCVSAGNFGQADALLDESAAIIAATG-APP---RP
MUL_2555|M.ulcerans_Agy99 GAATIALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLR
Mflv_4504|M.gilvum_PYR-GCK GAESDMMAIAGFLAINHLWRGQITDAEAEAAEAVERAEQLGGDDVLIIPM
MAV_0578|M.avium_104 PGLAYANLALLLGN-AELARGAAAEAARLVQEALAGAQIHEVTSG--LRP
MLBr_02341|M.leprae_Br4923 VAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQEITR--EL
Mb0393|M.bovis_AF2122/97 FALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTA
Rv0386|M.tuberculosis_H37Rv FALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTA
TH_3225|M.thermoresistible__bu YHRLIIAAWRGDAVEAARLIEAAAADGEARGEGR----------------
Mvan_5002|M.vanbaalenii_PYR-1 YQTLTLAAWRGEPADAEAVIEAAIADANARGEGR----------------
MAB_3361|M.abscessus_ATCC_1997 YHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGR----------------
MSMEG_1691|M.smegmatis_MC2_155 AHAAMLAAWRGDVAETTRLTEG-------LGAGR----------------
MMAR_0085|M.marinum_M AIKTYLAAYRGQEQICREGVQQTVDSAASRGEGY----------------
MUL_2555|M.ulcerans_Agy99 GYLGVISACRGDVVRARELAAQVRVWAEPRRVGF----------------
Mflv_4504|M.gilvum_PYR-GCK TVRGAIAAYAGRVDDARADARWVLAAVRNRKASH----------------
MAV_0578|M.avium_104 ASYFALAEAHGRLGHPAQANEAIAGARSCVPPDF----------------
MLBr_02341|M.leprae_Br4923 AERGVLTGERGRYACSTDVAEVCVP-------------------------
.
Mb0393|M.bovis_AF2122/97 QHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQS-
Rv0386|M.tuberculosis_H37Rv QHASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQS-
TH_3225|M.thermoresistible__bu -------------LMGLTGYAAALLYNGIGRYREALAAARTTCEYEDLG-
Mvan_5002|M.vanbaalenii_PYR-1 -------------VLGAADYAFAVLYNGLGRYQEACSAARRACEYEDLG-
MAB_3361|M.abscessus_ATCC_1997 -------------LLGAMGYAAGVLNNSLGRYELAFMAARRACEHEDLG-
MSMEG_1691|M.smegmatis_MC2_155 -------------AVGVAGHAVAVLNNGLGHYEQAFAAAQQACEYEDLG-
MMAR_0085|M.marinum_M -------------DVSVAMYAAAILHNGLGQYQEAFNAAASGARYDDVG-
MUL_2555|M.ulcerans_Agy99 -------------LTGAVAQIAILCSFAEGDYESAYLQATAITAPGEFPP
Mflv_4504|M.gilvum_PYR-GCK -------------IADWPGMTLCFLEESLGNHREALAALDDSFIAAGPPT
MAV_0578|M.avium_104 -----------LFMHTGLALATGWALAAGGQLREAVATAQAAARLARDR-
MLBr_02341|M.leprae_Br4923 ------------------ATLQATIAARIDRLSPPAKQLLVAAAVIGFR-
Mb0393|M.bovis_AF2122/97 ---MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLP
Rv0386|M.tuberculosis_H37Rv ---MTGHHLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLP
TH_3225|M.thermoresistible__bu ---FYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWGLGALAG
Mvan_5002|M.vanbaalenii_PYR-1 ---VHSWVLAELVEAADHCGDTALAVSALERLQERTADTGTDWGLGTLAG
MAB_3361|M.abscessus_ATCC_1997 ---LYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVAR
MSMEG_1691|M.smegmatis_MC2_155 ---FHGGTLVELIEAGTRCGQRDSATEALYLLEERTTQAGTAWAAAALAG
MMAR_0085|M.marinum_M ---MCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALGIGAS
MUL_2555|M.ulcerans_Agy99 LALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRLAIATGA
Mflv_4504|M.gilvum_PYR-GCK TELMYAWHLPDAIEAMVGVGRLDDAEILTAALERNGVEHDRRWMRAVGAR
MAV_0578|M.avium_104 ---GQPTHELACIQAAAQWG------DAAGAVRARALADALSLPLADAIA
MLBr_02341|M.leprae_Br4923 ----FGSDLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVA
:
Mb0393|M.bovis_AF2122/97 DVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYV
Rv0386|M.tuberculosis_H37Rv DVLECLAGL----ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYV
TH_3225|M.thermoresistible__bu ARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREH
Mvan_5002|M.vanbaalenii_PYR-1 AQALVADDD----HAEALFEESIDRLARTRVAVHLARAHLRYGEWLRRAL
MAB_3361|M.abscessus_ATCC_1997 SRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCN
MSMEG_1691|M.smegmatis_MC2_155 GRALLSSGR----RADGLHRESIEHYERTRLTVQAARARLRYGEWLRRAN
MMAR_0085|M.marinum_M ATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLTYGEWLRRER
MUL_2555|M.ulcerans_Agy99 AEALCASDE----RAPALFEKVLGHPAVASFPFEHARIRLAYGMRLRRLR
Mflv_4504|M.gilvum_PYR-GCK CRAMLLAAHGDVAAAEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLR
MAV_0578|M.avium_104 CHAEALRAG----NGEALLTVAAAYRAIGDAAAAADAAAQASAAFVEG-Q
MLBr_02341|M.leprae_Br4923 YESQLKSDR-------ARLHRRLAAAIEARAPHSVDQHAVLIAEHLEAAG
.
Mb0393|M.bovis_AF2122/97 QSVTALRDAMGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWES
Rv0386|M.tuberculosis_H37Rv QSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWES
TH_3225|M.thermoresistible__bu RRGEARRELNEAHGMFTRMGA-QGFAERSRRELIAVGEKVRRQPLTSGDE
Mvan_5002|M.vanbaalenii_PYR-1 RRNDAREQLTLASGMFTRFGA-AAFAERTRRELIATGEKARRQPVTSGAQ
MAB_3361|M.abscessus_ATCC_1997 RRSDARTELTAAHGSFVNMGT-AAFAERAERELRATGAKVRKRSASSEKA
MSMEG_1691|M.smegmatis_MC2_155 RRPDAVRELTAAHEVFVRIGA-QAFAERARRELVAAGPTARRVPGRSGEQ
MMAR_0085|M.marinum_M RRSEARSQLRIAYDMFAQMGA-AGFAERARRELSATGEAVYVQPTGITVD
MUL_2555|M.ulcerans_Agy99 RYRNARVVLRAAAEIFAGLGA-EPWTQRARNELRAAGTAVRHSAAVGPAP
Mflv_4504|M.gilvum_PYR-GCK QKATAAKNLTDALHTFEQLGT-PLWAQRARSELARAVVAP-------AEG
MAV_0578|M.avium_104 QHQRGRYAAALAGELAEECGGLCTPALRTP----------------AGLK
MLBr_02341|M.leprae_Br4923 DLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALTAEDP--HRAAM
.
Mb0393|M.bovis_AF2122/97 LTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQ
Rv0386|M.tuberculosis_H37Rv LTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQ
TH_3225|M.thermoresistible__bu LTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQ
Mvan_5002|M.vanbaalenii_PYR-1 LTAQESQIARLAGDGLTNQEIGAQLFISTHTVDWHLRKVFVKLGITSRRQ
MAB_3361|M.abscessus_ATCC_1997 LTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQ
MSMEG_1691|M.smegmatis_MC2_155 LTAQETQVAGLAARGLTNQEIAAQLFISPHTVEWHLRKVFVKLGITSRRQ
MMAR_0085|M.marinum_M LTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRE
MUL_2555|M.ulcerans_Agy99 LTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAG
Mflv_4504|M.gilvum_PYR-GCK LTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTRIYRKLGISSRAE
MAV_0578|M.avium_104 LSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDE
MLBr_02341|M.leprae_Br4923 CIAPRTRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDH
. : :. * * . . . .. .
Mb0393|M.bovis_AF2122/97 LAQAAARRT-------------
Rv0386|M.tuberculosis_H37Rv LAQAAARRT-------------
TH_3225|M.thermoresistible__bu LRAAPRVTATW-----------
Mvan_5002|M.vanbaalenii_PYR-1 LRSASWAS--------------
MAB_3361|M.abscessus_ATCC_1997 LRSGR-----------------
MSMEG_1691|M.smegmatis_MC2_155 LRTHGPRTTGFQGSAFEVERRA
MMAR_0085|M.marinum_M LRAILMESP-------------
MUL_2555|M.ulcerans_Agy99 LHDALDAIHAAPDQI-------
Mflv_4504|M.gilvum_PYR-GCK LGRRMDQPGL------------
MAV_0578|M.avium_104 LATIIRSRPAGRES--------
MLBr_02341|M.leprae_Br4923 VYQDRLH---------------
: