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DRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSELVPTGTVTLLLADIEGATHLP GSQLDTTAIAKLDRTLTELVREHRGVCPVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHT GEVSSPDEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGTYRLDDLPRPERVVQ LCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVDEVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVAS AVADGYPDGVWYVNLAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHLLDGCA ALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHGEAIELFTDRAREARPELEITADNLALVTEIC HRLDGIPLAIELAASRVRALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFR RLAVFPSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLLETVRQYALEKLRESG DADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWR ARGRLQEGLAWFAAALADHDAHPAGADPGLYARALADRALIDAVAGITDRLDDAQKALAIARDIEDPALL ARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLA DEIGDAFLSRSCRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDTEAAA AAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRFFGASAAAIINDPTSSAQISCARG DLNAAHRLADGAASITRGVHRARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLAS VMADAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAWAEGTALSIDEAIA YAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLA QQAARRGESERGPSRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2488c | - | - | 100% (1137) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (LUXR-FAMILY) |
| M. tuberculosis H37Rv | Rv0386 | - | 0.0 | 56.53% (1088) | LuxR/UHPA family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1358 | - | 0.0 | 51.97% (1093) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2515c | - | 0.0 | 100.00% (1137) | LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4504 | - | 4e-12 | 25.30% (502) | regulatory protein, LuxR |
| M. leprae Br4923 | MLBr_01753 | - | 0.0 | 50.73% (1092) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3361 | - | 8e-12 | 26.05% (453) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0123 | - | 0.0 | 54.16% (1117) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_2362 | - | 8e-17 | 24.57% (981) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0545 | - | 5e-21 | 40.70% (172) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3225 | - | 2e-13 | 26.01% (546) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2743 | - | 1e-109 | 42.09% (613) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 0.0 | 72.67% (1083) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Mvan_5928|M.vanbaalenii_PYR-1 -----------------------------------------------MSE
MMAR_0123|M.marinum_M ------------------------MLASMSEIDPRAEAPLVDWSDVDMGE
MLBr_01753|M.leprae_Br4923 ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 -----------------------------------------------MTE
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu ---------------------------------------MSSRDGDVVLH
Mflv_4504|M.gilvum_PYR-GCK ----------------------------------MRAALPAAMMNAMSDA
MAV_2362|M.avium_104 --------------------------------------------------
Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRG--
Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRG--
Mvan_5928|M.vanbaalenii_PYR-1 LVPTGTVTLLLADVQGSTQLWETQPETMTAAVAQLDRTLTDLVSDHDG--
MMAR_0123|M.marinum_M LLPTGTVTLLLADVEGSTRLWQNQPEPMTAAVAHLDSVLATTVATHHG--
MLBr_01753|M.leprae_Br4923 LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGG--
MUL_2743|M.ulcerans_Agy99 ------MTFLFTDVEGSTRLWESDPDRMRAALAAHDAVLTRTIQTHRG--
MSMEG_0545|M.smegmatis_MC2_155 KLSTGTKTLLMARVDRAEELWQTELDQTIAAIPWLRASMAHLIALNDG--
MAB_3361|M.abscessus_ATCC_1997 ------------------------MLRGQAGVGKTALLRYVLGKASGQ--
TH_3225|M.thermoresistible__bu GRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGKTALLGQLLGDAAGM--
Mflv_4504|M.gilvum_PYR-GCK SPQAADDPQVAGFLCTATSAPTGLIIEGDAGIGKTTLWLSLLQTARMRGF
MAV_2362|M.avium_104 --MGREAELRRSLAALSNAEFHGVALVGDAGVGKSTLARMLAKTVESA--
.:
Rv2488c|M.tuberculosis_H37Rv VCPVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSS
Mb2515c|M.bovis_AF2122/97 VCPVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSS
Mvan_5928|M.vanbaalenii_PYR-1 VRPVEQGEGDSFVVAFTRASDAVACALALQRAPLAPIRLRIGVHTGEVRL
MMAR_0123|M.marinum_M VRPVEQGEGDSFVVAFASAREAIACALDLQRSPLGPIRLRIGVHTGDIQL
MLBr_01753|M.leprae_Br4923 VQQVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQI
MUL_2743|M.ulcerans_Agy99 WLFKHTGDG--VCAAFASPRSAVDAAVDAQRALELPVR--MGLATGEAEP
MSMEG_0545|M.smegmatis_MC2_155 TLQR--DASDSFVAAFDRASDAVMCALDLQLAPLEPFALCIGVHAVEHTD
MAB_3361|M.abscessus_ATCC_1997 LIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDPQREALTIAFGTRSG
TH_3225|M.thermoresistible__bu RCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSPQRDVLNVAFGRGAG
Mflv_4504|M.gilvum_PYR-GCK QVLTARVGQAESVMAFAALADLLGAVSDEHFAALPPLQRLALDRVLLRAG
MAV_2362|M.avium_104 ------GRTVRFALGTQTGSAVPLGAFSHAVSLMAVNEPAVMLAAAHNTL
Rv2488c|M.tuberculosis_H37Rv PDEG---NCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLN
Mb2515c|M.bovis_AF2122/97 PDEG---NCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLN
Mvan_5928|M.vanbaalenii_PYR-1 RDEG---NYVGPTINRTARLRELAHGGQTVLSGTTSDLVADLLPDGGWLS
MMAR_0123|M.marinum_M RDPNDPTNYIGPTINRTARIRELAHGGQTVISGATQLLVVDQLPDGAWLA
MLBr_01753|M.leprae_Br4923 SNDD--VNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLV
MUL_2743|M.ulcerans_Agy99 HDAD----YFGAVLNRAARVMATGHGGQILLTDSTANLIS-----GVDLL
MSMEG_0545|M.smegmatis_MC2_155 SADS----------DGAARLRDIARGGQTLISAAAAALVSARMPAHAALT
MAB_3361|M.abscessus_ATCC_1997 PPPD-----RFLIGLAVLSLLAAAAEHQPVLCVIDDAQWLDR----VSLQ
TH_3225|M.thermoresistible__bu PAPG-----RFLVGLAVLNLLAAAGADQPLLCVIDDAQWLDR----VSLQ
Mflv_4504|M.gilvum_PYR-GCK ADGP--ATDQRVVAAGFVSLLHILAADAPVLIAIDDVQWLDAS--SRTAI
MAV_2362|M.avium_104 SQDK----NLVVVVDDAQLLDPLSATLVNQLAAWRSARLIVTIRSGEPVL
: :
Rv2488c|M.tuberculosis_H37Rv DLGTYRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLV
Mb2515c|M.bovis_AF2122/97 DLGTYRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLV
Mvan_5928|M.vanbaalenii_PYR-1 DLGTHRLRDLPRPERVVQLCHADLSNEFPPLRAREEIGVQRLPAQLTSFV
MMAR_0123|M.marinum_M DLGLHPLRDLPRPERVMQLCHSGLQNDFPPLRTTKSIAVHRMPARLTRFV
MLBr_01753|M.leprae_Br4923 DLGSHLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFV
MUL_2743|M.ulcerans_Agy99 DLGSRRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGN-LRPALTSFV
MSMEG_0545|M.smegmatis_MC2_155 -----PLRDRVRHEPVYQLNHPGLR-------------------------
MAB_3361|M.abscessus_ATCC_1997 TLAFVTRRLGSEPVAMLFAVRDGTDSELAGLPELTVHG-------LRAAD
TH_3225|M.thermoresistible__bu TLGFVARRLMAEPVAMVFALRDDIHEALVGVPALAVPG-------LADAD
Mflv_4504|M.gilvum_PYR-GCK EFAVRRLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPPMDAGR
MAV_2362|M.avium_104 DAVTALLKERLLLTVHVDPFTREQTELLAG-------------TVLGGPV
Rv2488c|M.tuberculosis_H37Rv GRVDEVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWY
Mb2515c|M.bovis_AF2122/97 GRVDEVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWY
Mvan_5928|M.vanbaalenii_PYR-1 GRVDDMAQVRGLMDANRLVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWY
MMAR_0123|M.marinum_M GRIAQMADVRSLLADNRLVTLTGAGGAGKTRLAVEIAASAVDEFGDGLWY
MLBr_01753|M.leprae_Br4923 GRAAQIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSY
MUL_2743|M.ulcerans_Agy99 ARAAEIGQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADEFPDGVWL
MSMEG_0545|M.smegmatis_MC2_155 ---TEADEVP-HLPYGRVVR------------------------------
MAB_3361|M.abscessus_ATCC_1997 AGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEELAGGFGW
TH_3225|M.thermoresistible__bu ARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTYAVGELAGGFVS
Mflv_4504|M.gilvum_PYR-GCK LHALISHRLGRTLTRPVVLRIAEMSGGNPFYALELAHTHVNSGDSPPAAE
MAV_2362|M.avium_104 DPWVVDELLQRSSGNPLLLRGFLTAGRDTGALFRTAEGWQLRGPLRGDRE
.
Rv2488c|M.tuberculosis_H37Rv VNLAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNC
Mb2515c|M.bovis_AF2122/97 VNLAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNC
Mvan_5928|M.vanbaalenii_PYR-1 VDLAPITDPALVAITVARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNC
MMAR_0123|M.marinum_M VDLAPVSHAEAVPVTVARALGLSDQPGRSTVDALARFIGEHQVLVVLDNC
MLBr_01753|M.leprae_Br4923 FDLAPDTDHDIFPITVL--------------DNLRRCIGDRRMLMVLDNC
MUL_2743|M.ulcerans_Agy99 FELAAVSDPAAVPDAVAAVLGITQQAGKTVTQSVATALERRVRLLVFDNC
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 PDGGRLAG----------------QIEQTFLRRVQQLPAHTQTLLLAAAT
TH_3225|M.thermoresistible__bu PGAGSAPS----------------RIEENYVHRIRALPAQTRRLLLIAAA
Mflv_4504|M.gilvum_PYR-GCK PPLPATLADVVR-----------------RRVGLLDDATRTLLLGVACVA
MAV_2362|M.avium_104 LHDALEYR-------------------LQSLSSEEREVVEILATAGLLNW
Rv2488c|M.tuberculosis_H37Rv EHLLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG---
Mb2515c|M.bovis_AF2122/97 EHLLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG---
Mvan_5928|M.vanbaalenii_PYR-1 EHLLDACATLIDALLGACPALAMLATSREPIAVAGEQTWRVPPLALDD--
MMAR_0123|M.marinum_M EHLLDATAALLLELTGRCPAVRLLATSREPLGVPGEVTFLVPSLSVT---
MLBr_01753|M.leprae_Br4923 EYLLDVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPAD--
MUL_2743|M.ulcerans_Agy99 EHVRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGV
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 DPLGDVTLLARAAQQLGIPMHAIAPAEAADLVELSTRVRFRHPLVRS---
TH_3225|M.thermoresistible__bu EPIGDSALFLRAAALMGIAVDALAPAEAARVIQFGPRMRFFHPLMRS---
Mflv_4504|M.gilvum_PYR-GCK DPTVELLARAHGASTDEITAGLERAEAAGIVVLEGNRVRFTHPLLAGG--
MAV_2362|M.avium_104 DILRDICDAEAVAALERRGLIRLVTDGSHAVAQLTHPMLGEAATRHAG--
Rv2488c|M.tuberculosis_H37Rv --EAIELFTDRAREARPELEITAD-NLALVTEICHRLDGIP-LAIELAAS
Mb2515c|M.bovis_AF2122/97 --EAIELFTDRAREARPELEITAD-NLALVTEICHRLDGIP-LAIELAAS
Mvan_5928|M.vanbaalenii_PYR-1 --DAIELFTDRARRARPDFIISAD-DAAAVSEICHRLDGMP-LAIELAAA
MMAR_0123|M.marinum_M --EATELFTDRARRVRPDFAVTDD-NTTAVTEICNRLDCMP-LAIELAAA
MLBr_01753|M.leprae_Br4923 --EAVELFTERAALVQPGFSVTDG-NRQIVTEICQRLDGMP-LAIELAAA
MUL_2743|M.ulcerans_Agy99 VSAAGTLFVERAQSVAPGFAPTDAQDAAAIGEICRRLDGIP-LAIELAAS
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -AVYISANPLERRRIHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAWE
TH_3225|M.thermoresistible__bu -AAYRAADPRDRRAVHRALAEATDPGADPDRRAWHAANGVTGTDDAVAAE
Mflv_4504|M.gilvum_PYR-GCK --VYTDAGPTARRAMHRAIASVES---HPELRARHLALAASSGDDEIFAA
MAV_2362|M.avium_104 --------MVRTRQLNGKLARALQKHERTGSRHLRLPHLQS--RIRLAEF
Rv2488c|M.tuberculosis_H37Rv RVRALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPE
Mb2515c|M.bovis_AF2122/97 RVRALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPE
Mvan_5928|M.vanbaalenii_PYR-1 RVRALSLTEIVDGLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPE
MMAR_0123|M.marinum_M RVRALSIDEIRTGLHDRFRLLTGGARTVVRRQQTLRASVDWSHALLTEPE
MLBr_01753|M.leprae_Br4923 RIRTLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESE
MUL_2743|M.ulcerans_Agy99 RMASMTPIEVRDRLDHRFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAE
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LEQSAGRAQAKGGVLAAAAFLQRATELTADPAARGRRALAAAQSKYDAAA
TH_3225|M.thermoresistible__bu LEKSAARAQQRGGIAATATFLERAVVLTADPGLRGRRALAAAQAKRDAAD
Mflv_4504|M.gilvum_PYR-GCK LDQAADSARARGAPAAAAELMDLALGLGAHDPMRRLKAAENHFLAGDTAK
MAV_2362|M.avium_104 MLHSDMEPDLDVITEAARDALAMSNVQLGEELARFALDRGGGLPAALVLA
Rv2488c|M.tuberculosis_H37Rv QVLFRRLAVFPSGFDLDGAQAAAAGGDVQR-YEVVDLLSLLADKSLVVTD
Mb2515c|M.bovis_AF2122/97 QVLFRRLAVFPSGFDLDGAQAAAAGGDVQR-YEVVDLLSLLADKSLVVTD
Mvan_5928|M.vanbaalenii_PYR-1 RVLFRRLAVFAGGFDLDGAQAITVDGEVHR-YEVVDLLTLLVDKSLLIAE
MMAR_0123|M.marinum_M RVLFRRIAVFLGGFDLDAAQAVAGDSQVQR-YQVVDELALLVDKSLVIAE
MLBr_01753|M.leprae_Br4923 RALFRRLSAISGTFDLKVAYAVGHDDLEEP-DQVFDRLTMLIDKSLVIVE
MUL_2743|M.ulcerans_Agy99 KVLLERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVD
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 FDAARELLGVADMTPLDPLARARATRLRAK----IAFAESRVGAFGSVTV
TH_3225|M.thermoresistible__bu SAAAHDLLAIAERAPLSALEWARAVHLRAQ----LEFARSRAGDAGGPPV
Mflv_4504|M.gilvum_PYR-GCK AAAALGEVGSIEPPILRAMATSLLATVRMY-----DNEHRQAVDLLRSAL
MAV_2362|M.avium_104 EAVSWQGRGEEAGFVLAHAEPDGDDDWLIARWGCLRAANLFWGCGDAEAA
Rv2488c|M.tuberculosis_H37Rv DSDGRTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPS
Mb2515c|M.bovis_AF2122/97 DSDGRTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPS
Mvan_5928|M.vanbaalenii_PYR-1 NTAGRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELDAPS
MMAR_0123|M.marinum_M SGGGPTRYRLLETVRQYAQEKLAESGEVEAVRSRHVTYYKSVAKLLDAPT
MLBr_01753|M.leprae_Br4923 GRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPG
MUL_2743|M.ulcerans_Agy99 RLSGRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVW
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 SEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRGGAVEVAE
TH_3225|M.thermoresistible__bu GQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAPSGALLEAAD
Mflv_4504|M.gilvum_PYR-GCK DDAADNVPVQVQVLLRLSFALNSIGELDDAR--RYARDAVKLAEELGFPG
MAV_2362|M.avium_104 RREADTVKKRVSSEAGLHLIDALELSMAFFRGDVETTTELGPGLCESDAV
Rv2488c|M.tuberculosis_H37Rv VAG-HERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARG
Mb2515c|M.bovis_AF2122/97 VAG-HERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARG
Mvan_5928|M.vanbaalenii_PYR-1 VAG-HERRLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWRARG
MMAR_0123|M.marinum_M GTD-HERRLAQAEDELDNLRSAFGWSLETRDFDSALELATSLHPVWMTRG
MLBr_01753|M.leprae_Br4923 DID-HEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRG
MUL_2743|M.ulcerans_Agy99 DSPRQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFLVN
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 PARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEAD
TH_3225|M.thermoresistible__bu AVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELAR
Mflv_4504|M.gilvum_PYR-GCK ATSAALAWAVHVDFQCGRGLDETALARAMKLYDSTFDVPIIFR-------
MAV_2362|M.avium_104 PMATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSCGMGLHRFN----
Rv2488c|M.tuberculosis_H37Rv RLQEGLAWFAAALADHDAHPAGA---------DPGLYARALADRALIDAV
Mb2515c|M.bovis_AF2122/97 RLQEGLAWFAAALADHDAHPAGA---------DPGLYARALADRALIDAV
Mvan_5928|M.vanbaalenii_PYR-1 RLQEGQAWFDAALTDYEARPGEA---------DPAVYARALADRAFMDGH
MMAR_0123|M.marinum_M QGREGLAWLEAGLGNEAGLGNEAGLGNEDVQVSPSTLARALADKVTLLAW
MLBr_01753|M.leprae_Br4923 HMYEGLAWFDSIFEHKNIEHLVA---------PKEVLARAVANKVMLHAI
MUL_2743|M.ulcerans_Agy99 R-FEPLTWVEEAIER-----------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -RPANTS-------------------------------------------
TH_3225|M.thermoresistible__bu SRPAEVVH------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2362|M.avium_104 --------------------------------------------------
Rv2488c|M.tuberculosis_H37Rv AG-----ITDRLDDAQKALAIARDIEDPALLARALTACGGVAAYNADLAR
Mb2515c|M.bovis_AF2122/97 AG-----ITDRLDDAQKALAIARDIEDPALLARALTACGGVAAYNADLAR
Mvan_5928|M.vanbaalenii_PYR-1 VG-----ITDRLDQAQKALAMARDIDDPALLVRALTACGGLAAYNADVAR
MMAR_0123|M.marinum_M TG-----SMAGFDDAERALTIARELADPALLIRALVARGVITAYDADVAR
MLBr_01753|M.leprae_Br4923 LASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVAR
MUL_2743|M.ulcerans_Agy99 -----------------------AVDHPKLAFLHVLASQCYTTGRVQEAI
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------WMEQAFPIALESATHEVWDDDMWH
TH_3225|M.thermoresistible__bu --------------------------WLVPAFPVLQESAGHELWDENLVD
Mflv_4504|M.gilvum_PYR-GCK -------------------------------APFVHALAMSWTGRLEQAH
MAV_2362|M.avium_104 -------------------------------IGISEIIAATDAGDDRAAE
Rv2488c|M.tuberculosis_H37Rv PWLAEAVGLARAVGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSL
Mb2515c|M.bovis_AF2122/97 PWLAEAVGLARAVGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSL
Mvan_5928|M.vanbaalenii_PYR-1 PLLAEAVDLARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEAREL
MMAR_0123|M.marinum_M PYFDEAAQLARELGDSWRLSQILSLQTRAAMAAG-DPIALEAAGEEGLRI
MLBr_01753|M.leprae_Br4923 PYFAEAVELARTQGDKWTLSQIRLWG-VVGFCVSGDPVALRAAAEAADDL
MUL_2743|M.ulcerans_Agy99 RYADEAARLLAT--DRYEVPFGIEGWPSGACTSSGHPEQSVELCRTQLAL
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 HLATRAVHIAREVGALSLLPAALIYRAGMHVHAGELDAAAELVQEADAIS
TH_3225|M.thermoresistible__bu ALSEAVVRQARDAGALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESIT
Mflv_4504|M.gilvum_PYR-GCK QELTAVRGVCLERGAESDMMAIAGFLAINHLWRGQITDAEAEAAEAVERA
MAV_2362|M.avium_104 RIYKRYAAMAEGLPGAEAMVD--AMLGVVRLARGEFPAACAAFTRSISLF
Rv2488c|M.tuberculosis_H37Rv ADEIGDAFLSRSCRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSS
Mb2515c|M.bovis_AF2122/97 ADEIGDAFLSRSCRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSS
Mvan_5928|M.vanbaalenii_PYR-1 ADEMGDGFVSRICGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNG
MMAR_0123|M.marinum_M AEAIGDRTTSRECRGALGWVRAWRGDPIGALHQLGEAIAEASAAHDLLLL
MLBr_01753|M.leprae_Br4923 AQEIGDRFVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTR
MUL_2743|M.ulcerans_Agy99 GHDTHTLTLG-----CLVLALTIKGQCDEAEQLADALIESAEATRNPAAL
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AATGH-----APIRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGRLL
TH_3225|M.thermoresistible__bu AATDHR----GPVRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGRLM
Mflv_4504|M.gilvum_PYR-GCK EQLGGDDVLIIPMT-VRGAIAAYAGRVDDARADARWVLAAVRNRKASHIA
MAV_2362|M.avium_104 AKGFPSP--------WLVVVGAFQAQAEGARGDSTAAAAALWRADRAYGP
Rv2488c|M.tuberculosis_H37Rv CAGQACLAHALAHRGDTEAA-AAAQASIDTAVGLSPVLSGSACSALVFAT
Mb2515c|M.bovis_AF2122/97 CAGQACLAHALAHRGDTEAA-AAAQASIDTAVGLSPVLSGSACSALVFAT
Mvan_5928|M.vanbaalenii_PYR-1 CCGELVLAHSLAQRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVAN
MMAR_0123|M.marinum_M MISQVVQGFTYAYVGDADGACACADAVFTSSAELVGANEGLGYATAAIAC
MLBr_01753|M.leprae_Br4923 TFGLYVQTRALVHR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAA
MUL_2743|M.ulcerans_Agy99 CYALLAYGFTFRDTNPASALAAMRRG------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GAMGYAAGVLNNSLGRYELAFMAARR------------------------
TH_3225|M.thermoresistible__bu GLTGYAAALLYNGIGRYREALAAART------------------------
Mflv_4504|M.gilvum_PYR-GCK DWPGMTLCFLEESLGNHREALAALDDS-----------------------
MAV_2362|M.avium_104 HAAVFLPELELARAWERAAA------------------------------
Rv2488c|M.tuberculosis_H37Rv LAAGDVAAAEHARESATRFFGASAAAIINDPTSSAQISCARGDLNAAHRL
Mb2515c|M.bovis_AF2122/97 LAAGDVAAAEHARESATRFFGASAAAIINDPTSSAQISCARGDLNAAHRL
Mvan_5928|M.vanbaalenii_PYR-1 LAAGDVTAAEAASDSATRSFGPSEVAGIQDPNVAAQIACTRGDLDTARSL
MMAR_0123|M.marinum_M QAAGDATAAWKAYQKARELVGMDPQMAGVFP-FGALAPLVSGDLSAARRW
MLBr_01753|M.leprae_Br4923 LAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRL
MUL_2743|M.ulcerans_Agy99 -----------------------------------------------LRI
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK -----------------------------------------------FIA
MAV_2362|M.avium_104 --------------------------------------------------
Rv2488c|M.tuberculosis_H37Rv ADGAASITRGVHRARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAY
Mb2515c|M.bovis_AF2122/97 ADGAASITRGVHRARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAY
Mvan_5928|M.vanbaalenii_PYR-1 VDGAVSITRGVHRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGAR
MMAR_0123|M.marinum_M ADDVVSTSYGCYLSVALTARARVALAQGELGQADRDSHAALSCSAANGTT
MLBr_01753|M.leprae_Br4923 ADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQAS
MUL_2743|M.ulcerans_Agy99 AQDTGNRNSETHLAAVLCR---VEAKYGDPLSALDHFTLAIHNHHEAGNT
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ACEHEDLGLYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQ
TH_3225|M.thermoresistible__bu TCEYEDLGFYSWCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWGL
Mflv_4504|M.gilvum_PYR-GCK AGPPTTELMYAWHLPDAIEAMVGVGRLDDAEILTAALERNGVEHDRRWMR
MAV_2362|M.avium_104 -GDTQAATTHATQAAEIARAAGMHAAEMRTRHAAVRFGDRSQTARLERLA
Rv2488c|M.tuberculosis_H37Rv LWVPDILECLASVM----ADAGSNREAVRLFGAADAARGRMGAVRFGIYQ
Mb2515c|M.bovis_AF2122/97 LWVPDILECLASVM----ADAGSNREAVRLFGAADAARGRMGAVRFGIYQ
Mvan_5928|M.vanbaalenii_PYR-1 LEVPDTLECLARVV----GDGGSHHEAARLCGAAEAIRGRTGAVRFRIYD
MMAR_0123|M.marinum_M LGVADTLECLAELA----ATEGDRREAARLLASAEAIRHRTGEVRLKILD
MLBr_01753|M.leprae_Br4923 LGISDSMELLAELI----SQGDNHRQAGRLFGAASAQREKTGEVRFKVWD
MUL_2743|M.ulcerans_Agy99 TLISTPLAVLAAFF----DRLGRYEAAATIAGFAFHPITEASFP------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GMVARSRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGEW
TH_3225|M.thermoresistible__bu GALAGARALLADGD----EADRLFREALDHLSRSRVVVHRARVHLTYGEW
Mflv_4504|M.gilvum_PYR-GCK AVGARCRAMLLAAHGDVAAAEQMAHRAISEHDHLPMPFERARTRLLLGQL
MAV_2362|M.avium_104 RILDTPLAEAAADH-----ARGLTQRDGDLLDAAAQQFADLGALACAADA
Rv2488c|M.tuberculosis_H37Rv AGCNSSLATLRKSMGDSEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTS
Mb2515c|M.bovis_AF2122/97 AGCNSSLATLRKSMGDSEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTS
Mvan_5928|M.vanbaalenii_PYR-1 ADHETTVTTLRDALGDKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSS
MMAR_0123|M.marinum_M AHCEVVLAELRNELGEQDFAAVWGQGAVISTDEVISYVRRGRGTRRRPSS
MLBr_01753|M.leprae_Br4923 AGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTT
MUL_2743|M.ulcerans_Agy99 -ELRTTISHLRDALGDHAYESFSQSGAAMTTAAMATYAYHQIDHARTEFQ
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LRRCNRRSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRKRSAS
TH_3225|M.thermoresistible__bu LRREHRRGEARRELNEAHGMFTRMGAQGFAERSRRELIAVGEKVRRQPLT
Mflv_4504|M.gilvum_PYR-GCK QRRLRQKATAAKNLTDALHTFEQLGTPLWAQRARSELAR-------AVVA
MAV_2362|M.avium_104 AAQAAGEHARRGDRGKKFESSAWAH--ALASRYELHTPAVEAAARPLPFS
Rv2488c|M.tuberculosis_H37Rv GWGALTPTELEVALLVGEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLS
Mb2515c|M.bovis_AF2122/97 GWGALTPTELEVALLVGEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLS
Mvan_5928|M.vanbaalenii_PYR-1 GWASLTPTELDVVGLVSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLA
MMAR_0123|M.marinum_M GWGSLTPTEHDVVRLVQEGLSNKDIAARMFISPRTVQTHLTHVYTKLGLT
MLBr_01753|M.leprae_Br4923 GWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLT
MUL_2743|M.ulcerans_Agy99 AR------------------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 SEKALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGIT
TH_3225|M.thermoresistible__bu SGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGIT
Mflv_4504|M.gilvum_PYR-GCK PAEGLTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTRIYRKLGIS
MAV_2362|M.avium_104 G------RERQIVNLVAAGLSNREIADRLVISVRTVEGHLYRLFTKLGIN
Rv2488c|M.tuberculosis_H37Rv SRLQLAQQAARRGESERGPSRP----------------
Mb2515c|M.bovis_AF2122/97 SRLQLAQQAARRGESERGPSRP----------------
Mvan_5928|M.vanbaalenii_PYR-1 SRVQLAQEAARHT-------------------------
MMAR_0123|M.marinum_M SRIQLVHEVARHA-------------------------
MLBr_01753|M.leprae_Br4923 SRVQLVQEAARHN-------------------------
MUL_2743|M.ulcerans_Agy99 --------------------------------------
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------
MAB_3361|M.abscessus_ATCC_1997 SRRQLRSGR-----------------------------
TH_3225|M.thermoresistible__bu SRRQLRAAPRVTATW-----------------------
Mflv_4504|M.gilvum_PYR-GCK SRAELGRRMDQPGL------------------------
MAV_2362|M.avium_104 SREQLTLLVAREPRGRRELLGHSNPSLGDQDDVHPHAG