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APVTFVGRSGDLDELIRRTAATVSDGSAVVTVRGAPGIGKTALLRQVAATVPNSRWATAVPWESTVDGAV LSQLSPEPGAEQLARALAGDDPTLLVVDDAQHADSASLQALSTLIRHHRSLPVLLVLVTDGHPLPVPGLD GDELVMTGLDVREVAALASARGHVLPALMVDRLTRHTAGHPGHVRALLDELPAQTWSRLDAPLPAPREVV AQVERELAAAGDGGRALAFALAVLGEEATLSEAVLLAGIDDPLAAVAAATGAGLVRTGDPLEPRLRDPLA AAAVLDVCGVQATADAHRRAADVVTDPVARLRHRVAATPVPDEALADEVDALARSSGADGEWSRAAVLFR DAARLTAAPLLRDERLTRSVDALVAAGDCVGAAAMVPTVENLRETPLRNATLAYLAILRGRATEAEVRLR RAWDIVHIDRDTDTAAFIAQRHVLHALVHCQGEELVAWADRALALAERDSPAGIEAAAIRGLGLLASGQP RRAAAEYDDLHERVRHGAQAQRVVMGRGWVQLMRDDVEGARSSLESAVAAAGLGGSTRITLWSHAWLART QFSLGEWDAALASVAHGRRLAETSGIVLVTPLLEWTAGQIAALRGDWETAHAAAHAAAGGGEYAMMRIPA LLVRAQIAEAQADYATVRRVLEPLTTLAPGTSLQAGVLAVGRRPGQRDGAHR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1352 | - | - | 100% (683) | tetratricopeptide TPR_4 |
| M. gilvum PYR-GCK | Mflv_4504 | - | 2e-14 | 27.86% (359) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_1156 | - | 4e-14 | 24.39% (619) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1236c | - | 1e-09 | 27.22% (540) | hypothetical protein Mb1236c |
| M. tuberculosis H37Rv | Rv1204c | - | 1e-09 | 27.22% (540) | hypothetical protein Rv1204c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3361 | - | 8e-20 | 28.21% (560) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 4e-16 | 27.80% (428) | transcriptional regulatory protein |
| M. avium 104 | MAV_1348 | - | 3e-11 | 26.10% (659) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_1901 | - | 0.0 | 59.00% (683) | DNA-binding HTH domain-containing protein |
| M. thermoresistible (build 8) | TH_3225 | - | 2e-15 | 25.31% (569) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2033 | smc | 4e-06 | 25.51% (396) | chromosome partition protein Smc |
| M. vanbaalenii PYR-1 | Mvan_3871 | - | 7e-23 | 28.08% (463) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1236c|M.bovis_AF2122/97 -----MRVWKHV-----------EAAVDSPDRCGVVLVGPHGVGKTLLAQ
Rv1204c|M.tuberculosis_H37Rv -----MRVWKHV-----------EAAVDSPDRCGVVLVGPHGVGKTLLAQ
MAV_1348|M.avium_104 -----MPIRWNVPRQATAAERLDAALADTAAAAGAVVLGPDGIGKSTLAR
Mflv_1352|M.gilvum_PYR-GCK ----MAPVTFVGRSGDLDELIRRTAATVSDGSAVVTVRGAPGIGKTALLR
MSMEG_1901|M.smegmatis_MC2_155 --------MLCGRDRELSELGEHVAAAEHT-ARLVVLTGEPGIGKTALLR
MAB_3361|M.abscessus_ATCC_1997 -----------------------------------MLRGQAGVGKTALLR
TH_3225|M.thermoresistible__bu MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGKTALLG
MMAR_0085|M.marinum_M ----MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDAGIGKTTLLT
Mvan_3871|M.vanbaalenii_PYR-1 --------MLLGRESEQQRIAELVAGARLGQSGVLVVRGEAGIGKTALLE
MUL_2033|M.ulcerans_Agy99 --------MYLKSLTLKGFKSFAAPTTLRFEPGITAVVGPNGSGKSNVVD
: * * **: :
Mb1236c|M.bovis_AF2122/97 LAAEQVMSEDGRSGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPA
Rv1204c|M.tuberculosis_H37Rv LAAEQVMSEDGRSGRARWVVGTAPGRAIPFGAFRHLISLPASGADIGRPA
MAV_1348|M.avium_104 VAAERFAAAHPGT-RVRWVTGTPTERAVPFGAFSHLVRI----AEIGKPA
Mflv_1352|M.gilvum_PYR-GCK QVAATVPN--SRWATAVPWESTVDG-----AVLSQLS-------PEPGAE
MSMEG_1901|M.smegmatis_MC2_155 DLTQRHG---AWWALGASWETDLPG-----GVLAQLMQDDVPDDPLDGAA
MAB_3361|M.abscessus_ATCC_1997 YVLGKASG--QLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDPQRE
TH_3225|M.thermoresistible__bu QLLGDAAG--MRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSPQRD
MMAR_0085|M.marinum_M DLVDNAPD--LRVLRVRGAEMEMELTYSGVQQLCGPLMSLIGQLPEPQLD
Mvan_3871|M.vanbaalenii_PYR-1 DTAAHLGD--MTLVRASGTEAESTLEFSGLHQLLRPALHLIDRLPAPQCD
MUL_2033|M.ulcerans_Agy99 ALAWVMGEQGAKTLRGGKMEDVIFAGTSLRAPLGRAEVTVTIDNSDNALP
:
Mb1236c|M.bovis_AF2122/97 ALLRAARS-----------------------------------------S
Rv1204c|M.tuberculosis_H37Rv ALLRAARS-----------------------------------------S
MAV_1348|M.avium_104 ALLRAARA-----------------------------------------S
Mflv_1352|M.gilvum_PYR-GCK QLARALAG------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 HLVDHVRA------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ALTIAFGTRSGPPPD----------------------RFLIGLAVLSLLA
TH_3225|M.thermoresistible__bu VLNVAFGRGAGPAPG----------------------RFLVGLAVLNLLA
MMAR_0085|M.marinum_M ALEIALGRKRGRAPD----------------------RLLLGLAVLTLVG
Mvan_3871|M.vanbaalenii_PYR-1 ALAVALLMRDGPAPE----------------------RFAVGAATLSLLS
MUL_2033|M.ulcerans_Agy99 IEYTEVSITRRMFRDGASEYEINGSSCRLMDVQELLSDSGIGREMHVIVG
Mb1236c|M.bovis_AF2122/97 LTGDAGDLLLVVDDAHNLDPLSATLVYQLARAG-AARLVVTVASEAEPPD
Rv1204c|M.tuberculosis_H37Rv LTGDAGDLLLVVDDAHNLDPLSATLVYQLARAG-AARLVVTVASEAEPPD
MAV_1348|M.avium_104 LG-DAG-LLLVVDDAHQLDVLSATLVYQLARAG-AARLIVTARADG-APD
Mflv_1352|M.gilvum_PYR-GCK ----DDPTLLVVDDAQHADSASLQALSTLIRHHRSLPVLLVLVTDG-HPL
MSMEG_1901|M.smegmatis_MC2_155 ----AGVRLLLVDDAHHADVESLQALSTLVRHQRDLPVLVVLATQSVDAL
MAB_3361|M.abscessus_ATCC_1997 AAAEHQPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRDGTDS
TH_3225|M.thermoresistible__bu AAGADQPLLCVIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRDDIHE
MMAR_0085|M.marinum_M EASRASPILCVVDDAQWVDSASVQALAFVARRIHVDPVAMVFATRDRGPD
Mvan_3871|M.vanbaalenii_PYR-1 RYAEDSALLVLVDDAHLLDSPSADALTFVARRLLADPIAMVISTRPEPHA
MUL_2033|M.ulcerans_Agy99 QGKLDEILQSRPEDRRAFIEEAAGVLKHRKRKEKALRKLDAMSANLARLT
:* : : : *
Mb1236c|M.bovis_AF2122/97 AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG
Rv1204c|M.tuberculosis_H37Rv AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG
MAV_1348|M.avium_104 AIAALWDDGLLTRIDVEAPDAPTS--------------------------
Mflv_1352|M.gilvum_PYR-GCK PVPGLD----GDELVMTGLDVREVAALASARG-HVLPALMVDRLTRHTAG
MSMEG_1901|M.smegmatis_MC2_155 PIPLAA----DDVVELTGLPVAAVVELARLRG-ITIHPTLADRLTRHAGG
MAB_3361|M.abscessus_ATCC_1997 ELAG------LPELTVHGLRAADAGTLLDSVIPGLLDERVRDRIVAETQG
TH_3225|M.thermoresistible__bu ALVG------VPALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRG
MMAR_0085|M.marinum_M ALTG------HCELSLQGLEDHDARLVLSTAIPGRLNDSVAETVLAEANG
Mvan_3871|M.vanbaalenii_PYR-1 AFTATD----LPVLDLGGLDLAAASELISRSAPNPTTAEDAEHLHRVTLG
MUL_2033|M.ulcerans_Agy99 DLTTELRR-QLKPLGRQAEVARRAQTIQADLRDARLRLAADDVVSRRAER
. :
Mb1236c|M.bovis_AF2122/97 NPLYLRHLIDGGGLEHVDGRWRCRDEDRRPLSGVIDEYLCALPEPARAVV
Rv1204c|M.tuberculosis_H37Rv NPLYLRHLIDGGGLEHVDGRWRCRDEDRRPLSGVIDEYLCALPEPARAVV
MAV_1348|M.avium_104 -------------------------------PGEIDAFLAELTPPARAVL
Mflv_1352|M.gilvum_PYR-GCK HPGHVRALLDELPAQTWSR----LDAPLPAPREVVAQVERELAAAGDGGR
MSMEG_1901|M.smegmatis_MC2_155 NPRDVLALFDEVPASAWAR----LDSSLPAPRHVVERVATQLDSCGPAGR
MAB_3361|M.abscessus_ATCC_1997 NPLALLELPRDMTAEELAGGFG-WPDGGRLAGQIEQTFLRRVQQLPAHTQ
TH_3225|M.thermoresistible__bu NPLALLEVPRTYAVGELAGGFV-SPGAGSAPSRIEENYVHRIRALPAQTR
MMAR_0085|M.marinum_M NPLALLELHNALIRGELAGGYG-LANATRTETQIERTFVSRLRALPSETK
Mvan_3871|M.vanbaalenii_PYR-1 SPLALVELSRDIERVRDSP----PVLPVPVSDAVAQAFGRRITALPDSTR
MUL_2033|M.ulcerans_Agy99 EAIFEAEATMRREHDEAAARLTVAAEELAAHEATLAELTSRAESVQHTWF
Mb1236c|M.bovis_AF2122/97 DYLAIAEPLART---------------------DLVALVGGEQLDTLG--
Rv1204c|M.tuberculosis_H37Rv DYLAIAEPLART---------------------DLVALVGGEQLDTLG--
MAV_1348|M.avium_104 EYLAVAEPLSVT---------------------DLNALAGDGAVAEAQ--
Mflv_1352|M.gilvum_PYR-GCK ALAFALAVLG-----------------------EEATLSEAVLLAGID--
MSMEG_1901|M.smegmatis_MC2_155 ALVQALAVLGAAGGGD------------ATDATDTVTLAEAADLAGLSGP
MAB_3361|M.abscessus_ATCC_1997 TLLLAAATDPLG---------------------DVTLLARAAQQLGIP--
TH_3225|M.thermoresistible__bu RLLLIAAAEPIG---------------------DSALFLRAAALMGIA--
MMAR_0085|M.marinum_M TFLLVAAAESTA---------------------RPEWLWAAAHRLGIG--
Mvan_3871|M.vanbaalenii_PYR-1 -LALLLAVVADG---------------------DLGLASRAAAEMGTS--
MUL_2033|M.ulcerans_Agy99 GLSALAERVGTTVRIANERAQHLDVEPVTNSDTDPDALDAEAEQVAIAEQ
Mb1236c|M.bovis_AF2122/97 -----QAEAAGAVRVGPDSDTSEIFVGHPLYADRARAVLTAEHAHALRVS
Rv1204c|M.tuberculosis_H37Rv -----QAEAAGAVRVGPDSDTSEIFVGHPLYADRARAVLTAEHAHALRVS
MAV_1348|M.avium_104 -----RWGAAETRMRGGTSDDPVVYTAHPLFAERVRAALDPDDARQRRTE
Mflv_1352|M.gilvum_PYR-GCK -DPLAAVAAATGAGLVRTGDPLEPRLRDPLAAAAVLDVCGVQATADAHRR
MSMEG_1901|M.smegmatis_MC2_155 SEPLAALDEAVDAGLVTHVVHFEPRLTDGLTGPAVLTLLGARATAEAHRR
MAB_3361|M.abscessus_ATCC_1997 ---MHAIAPAEAADLVELST--RVRFRHPLVRSAVYISANPLERRRIHGV
TH_3225|M.thermoresistible__bu ---VDALAPAEAARVIQFGP--RMRFFHPLMRSAAYRAADPRDRRAVHRA
MMAR_0085|M.marinum_M ---PEAAAPAEAAGLIAAQG--SVRFRHPLIRAAVYHSSSAAERRRVHAA
Mvan_3871|M.vanbaalenii_PYR-1 ---LAPIVEAESIELMRINAG-RVDFRHPLVRSAVYAAADAQTRRDVHRA
MUL_2033|M.ulcerans_Agy99 QLLVELAEARDRLDAARAELADREHRAAEADRAHLAAVRAEADRREGLAR
Mb1236c|M.bovis_AF2122/97 LVAQLAK--HPSDHVSDQLRLSSLAIDVPASATPAAVTDAATAAGQALRL
Rv1204c|M.tuberculosis_H37Rv LVAQLAK--HPSDHVSDQLRLSSLAIDVPASATPAAVTDAATAAGQALRL
MAV_1348|M.avium_104 LVTVLAR--HPSDRLSDRLRLVSLALDSDAPPRAADVVDAAR---QALRL
Mflv_1352|M.gilvum_PYR-GCK AADVVT---DPVARLRHRVAATPVPDEALADEVDALARSSGADGEWSRAA
MSMEG_1901|M.smegmatis_MC2_155 AAEVIT---DPRRRLRHRVAAAAAPDEALAGEVDALARASGADGAWALAA
MAB_3361|M.abscessus_ATCC_1997 LAGATDPGADPDRRAWHRAHAAAGTDEAIAWELEQSAGRAQAKGGVLAAA
TH_3225|M.thermoresistible__bu LAEATDPGADPDRRAWHAANGVTGTDDAVAAELEKSAARAQQRGGIAATA
MMAR_0085|M.marinum_M LAASIAGPDDDDHRVWHRAHAAEAPDAQTADDLERSAERARARGGLSAAA
Mvan_3871|M.vanbaalenii_PYR-1 VAAAMP-AAAHTRRVWHLSEAVVGPDDAVADDLVDLAEKATARGAHGVAA
MUL_2033|M.ulcerans_Agy99 LAGQVETMRARVESIDDSVARLSERIEHAAARAQQTRAEFETVQARVGEL
. . *
Mb1236c|M.bovis_AF2122/97 GDVRLAERLARAALDRSDALAARLPLAYALGWQGRGREADAVLAAVNPAE
Rv1204c|M.tuberculosis_H37Rv GDVRLAERLARAALDRSDALAARLPLAYALGWQGRGREADAVLAAVNPAE
MAV_1348|M.avium_104 GDLALGERLARAALRRSGGLAARLALAHALGWQGRGREADALLAEVDSTG
Mflv_1352|M.gilvum_PYR-GCK VLFRDAARLTAAPLLRDERLTRSVDALVAAGDCVGAAAMVPTVENLRETP
MSMEG_1901|M.smegmatis_MC2_155 TLFHDASRLTSDPLLRDERLTRSVDALVAAGDCGAAAQLIPVVESLRETP
MAB_3361|M.abscessus_ATCC_1997 AFLQRATELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDP
TH_3225|M.thermoresistible__bu TFLERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSA
MMAR_0085|M.marinum_M SFLEHATKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAAADDE
Mvan_3871|M.vanbaalenii_PYR-1 NALTRSAELTNDDVLRCARLIRAGEAAWFAGHLTRARGLIDDAEAIAAGP
MUL_2033|M.ulcerans_Agy99 DQGEVGLDEQHERTVAALRLAEQRLAELQVAERDAERQVASLRARIGALS
. .
Mb1236c|M.bovis_AF2122/97 LTETELMAW------------------------AIPRAANRFWMLNEPER
Rv1204c|M.tuberculosis_H37Rv LTETELMAW------------------------AIPRAANRFWMLNEPER
MAV_1348|M.avium_104 LTEAALMDW------------------------ALLRAANQFWMLSEPER
Mflv_1352|M.gilvum_PYR-GCK LRNATLAYLAILRGR-------------ATEAEVRLRRAWDIVHIDRDTD
MSMEG_1901|M.smegmatis_MC2_155 LRNAVLAYLAILRGR-------------ATEAEVRLRRAWDIVNAERDPE
MAB_3361|M.abscessus_ATCC_1997 LARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNLA
TH_3225|M.thermoresistible__bu LEWARAVHLRAQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPAA
MMAR_0085|M.marinum_M LIAARCELIRAKIAFAASRG--------SDAPPLLLAAAQRMQRLDPSES
Mvan_3871|M.vanbaalenii_PYR-1 DTLTQISALRGHIALRSGSLR--------DAHDLLVDAAARTDAAEADAT
MUL_2033|M.ulcerans_Agy99 VGLDRKDGAAWLARNHSDAGLFGSVAQLVKVRSGYEAAVAAVLGSAAEAL
.
Mb1236c|M.bovis_AF2122/97 ATAFLQTTRS----------------------------------------
Rv1204c|M.tuberculosis_H37Rv ATAFLQTTRS----------------------------------------
MAV_1348|M.avium_104 ATAFLRTVRN----------------------------------------
Mflv_1352|M.gilvum_PYR-GCK TAAFIAQRHVLHALVHCQGE------------------ELVAWADRALAL
MSMEG_1901|M.smegmatis_MC2_155 TAALIAQRYVLHSLVRGRGT------------------ELVRWADTALRL
MAB_3361|M.abscessus_ATCC_1997 RETYLDAVGAAMYGGRLCP----------------RGGAVEVAEPARLAP
TH_3225|M.thermoresistible__bu RESYLEAFAALMYAGRLAP----------------SGALLEAADAVQAAF
MMAR_0085|M.marinum_M RKAYLGAVLASILVGRMATDQ--------------HNSSPSVAKAASNAP
Mvan_3871|M.vanbaalenii_PYR-1 VGLLADAVTACFYMCDTAAG------------------LALADRIEVLLP
MUL_2033|M.ulcerans_Agy99 AADSFGAARSAVTALKQADGGRAALVLGDWPDAHDHRAAGGLPSGTLWAL
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 --------------------------------------------------
Mflv_1352|M.gilvum_PYR-GCK AERDSPAGIEAAAIRGLGLLASGQPRRAAAEYDDLHERVRHGAQAQRVVM
MSMEG_1901|M.smegmatis_MC2_155 ADRESPTAVESAAVRGLGLAAAGRAEQATAAYDELAERITHGAQAQRVTL
MAB_3361|M.abscessus_ATCC_1997 AGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEAD-RPANT
TH_3225|M.thermoresistible__bu ARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEV
MMAR_0085|M.marinum_M AAPHP-PRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERDIGVAEP
Mvan_3871|M.vanbaalenii_PYR-1 ACRTGSARTRGQLAIGVARVIAG---------GDGMRWLRIAVETLNNEP
MUL_2033|M.ulcerans_Agy99 DLIEVPSRLRPAMTAMLSGVVVVNDLSEALDLVQAQPQLRAVTLDGDLVG
Mb1236c|M.bovis_AF2122/97 -------------------------------RVTEPTARSTLD------A
Rv1204c|M.tuberculosis_H37Rv -------------------------------RVTEPTARSTLD------A
MAV_1348|M.avium_104 -------------------------------RVADPGPRTTLD------A
Mflv_1352|M.gilvum_PYR-GCK GRGWVQLMR----------DDVEGARSSLESAVAAAGLGGSTR------I
MSMEG_1901|M.smegmatis_MC2_155 GRGWLQLIR----------DDVDGARSNLESAIATANLGGSSR------I
MAB_3361|M.abscessus_ATCC_1997 S-WMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVGALS------L
TH_3225|M.thermoresistible__bu VHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDAGALA------G
MMAR_0085|M.marinum_M G-WHDLTARVCLD-----LFDQDAYNFLAARQVEDLRAAGALT------M
Mvan_3871|M.vanbaalenii_PYR-1 SVLDDPRRPDWSIVGALFLRETAAGRDLMQRVVQDRRKRTAIG------A
MUL_2033|M.ulcerans_Agy99 AGWVSGGSDRKPSTLEITSEIDKARRELAAAEVRVAELGAALSGALTDQT
: :
Mb1236c|M.bovis_AF2122/97 LAATFAMNS------GNLPRAITLATEVLSGPAADDMAVAWAASAAALSS
Rv1204c|M.tuberculosis_H37Rv LAATFAMNS------GNLPRAITLATEVLSGPAADDMAVAWAASAAALSS
MAV_1348|M.avium_104 LSATFAMNT------GNVGHAVKVAGEVLGSPAADDQAVAWAGSAAALCA
Mflv_1352|M.gilvum_PYR-GCK TLWSHAWLARTQFSLGEWDAALASVAHGRRLAETSGIVLVTPLLEWTAGQ
MSMEG_1901|M.smegmatis_MC2_155 TLWAMAWLARAHFVSGDWDAALATVVSGRDLAASSGITITTPLLEWIAAQ
MAB_3361|M.abscessus_ATCC_1997 LPAALIYRAGMHVHAGELDAAAELVQEADAISAATGH-APIRYHSLILAA
TH_3225|M.thermoresistible__bu LPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHRLIIAA
MMAR_0085|M.marinum_M LPVALVTFAGVCVSAGNFGQADALLDESAAIIAATGA-PPRPAIKTYLAA
Mvan_3871|M.vanbaalenii_PYR-1 LPNLLFHTARDDATTDNWQSALASYTESVALARETSQSTDLAASLAGLAW
MUL_2033|M.ulcerans_Agy99 ARQDAAEQALAALNESDTAISAMYEQLGRIGQDARGAEEEWTRLLRQREE
: .: : .
Mb1236c|M.bovis_AF2122/97 ARMGRFGDVDRLAERASAAEHPGLLRFTVGLAQITSLLLAGDVAPAQELA
Rv1204c|M.tuberculosis_H37Rv ARMGRFGDVDRLAERASAAEHPGLLRFTVGLAQITSLLLAGDVAPAQELA
MAV_1348|M.avium_104 ARQGRFDDVEPLARRALAAEHPGLLRFTIGLAQTTTLLLAGRLEQARELA
Mflv_1352|M.gilvum_PYR-GCK IAALRGDWETAHAAAHAAAGG-GEYAMMRIPALLVRAQIAEAQADYATVR
MSMEG_1901|M.smegmatis_MC2_155 ISALRGDWETAHAAVQAADRVTQDYEMMRIPTILARAQVAEAEADYPKVR
MAB_3361|M.abscessus_ATCC_1997 WRGSEPTAIRLIDEAMRDGAARGEGRLLGA-MGYAAGVLNNSLGRYELAF
TH_3225|M.thermoresistible__bu WRGDAVEAARLIEAAAADGEARGEGRLMGL-TGYAAALLYNGIGRYREAL
MMAR_0085|M.marinum_M YRGQEQICREGVQQTVDSAASRGEGYDVSV-AMYAAAILHNGLGQYQEAF
Mvan_3871|M.vanbaalenii_PYR-1 LQARMGRFAECRVNAAEARQLARRHHITFA-HLWAQFALGDSALAEGNAG
MUL_2033|M.ulcerans_Agy99 LEVGRTQTLEEVLELESRLRNAQESQHVQAAEPVDRQEIAAAAESARAIE
:
Mb1236c|M.bovis_AF2122/97 KRFTDFA-------------------------------------------
Rv1204c|M.tuberculosis_H37Rv KRFTDFA-------------------------------------------
MAV_1348|M.avium_104 QQFTDFAELQQPGRAIG---------EVLVAHVLLTEGEFASAAALLGPA
Mflv_1352|M.gilvum_PYR-GCK RVLEPLTTLAP---GTSLQAG-------VLA-------------------
MSMEG_1901|M.smegmatis_MC2_155 RVLEPLAALAARAPGTVLTEPGYWPWPDVLANALVIDGALDEADEFLRPH
MAB_3361|M.abscessus_ATCC_1997 MAARRACEHEDLGLYS-------WCLIELIEAAVRCG----EHDTAVKAF
TH_3225|M.thermoresistible__bu AAARTTCEYEDLGFYS-------WCLHELVEAAARVG----ETDTAHRAL
MMAR_0085|M.marinum_M NAAASGARYDDVGMCG-------YLLGELIEAAVRCK----EHNAATEAL
Mvan_3871|M.vanbaalenii_PYR-1 EAIVHYQGMESLLTDNRFRDVDLAPGPELAEAHMRHG----DAAAAHEVA
MUL_2033|M.ulcerans_Agy99 VEARLTVRTAEERANALRGRADSLRRVAAAEREARVRAELARAVRLRSAA
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 AATLERTGYSWGPLSLTLLATALAQLGDTAATAKALSRAETRHGTKS--A
Mflv_1352|M.gilvum_PYR-GCK --VGRRPGQRDGAHR-----------------------------------
MSMEG_1901|M.smegmatis_MC2_155 EEVARERGHRSAMARLGYARGRLLGARGELSAARARFEESLALLDGLPLR
MAB_3361|M.abscessus_ATCC_1997 GQLEERALAAQSDWSQGMVARSRALIT-VGHDAEPHYREAIQRLTNTRIS
TH_3225|M.thermoresistible__bu GDIEERAGASGTPWGLGALAGARALLA-DGDEADRLFREALDHLSRSRVV
MMAR_0085|M.marinum_M GRLLKRTKASGTPTALGIGASATALVS-DGSIADAAYREAITHLRRSPVA
Mvan_3871|M.vanbaalenii_PYR-1 VGYLGRAQEKSQPWALARAHRAMALTAGEPGVCEAHFSEALRLHELNPDR
MUL_2033|M.ulcerans_Agy99 VAAAVAESGRLLAWRLNRVVDAASQLRDELAAERQQRSAAMSAVREETSS
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 LFAPELGVARAHRLALMRDAHGAVAAARDAARMAERGGQRA---------
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 YDRARVNFAYGQTLRRAGKRRDADAVIATARDLYLSLGAHT---------
MAB_3361|M.abscessus_ATCC_1997 AHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAA---------
TH_3225|M.thermoresistible__bu VHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQG---------
MMAR_0085|M.marinum_M VHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAG---------
Mvan_3871|M.vanbaalenii_PYR-1 FEAARTRLAFGSSLRRIKKRVAARPHLRAALEDFERLGARP---------
MUL_2033|M.ulcerans_Agy99 LSARVATLTDSLHRDEVANAQAALRIEQVEQMVLEQFGMAPSDLVAEYGP
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 --------VAARVWHEAVRLGDTRAAEPLARLCDEIDCAAARIALAHARA
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 --------YVARCDRELKAG-GLHQLRGSR-DSVELTPQEDAVTALVAQG
MAB_3361|M.abscessus_ATCC_1997 --------FAERAERELRATGAKVRKRSAS-SEKALTAQEAQIARMAGQG
TH_3225|M.thermoresistible__bu --------FAERSRRELIAVGEKVRRQPLT-SGDELTAQEAQIAGLAADG
MMAR_0085|M.marinum_M --------FAERARRELSATGEAVYVQPTG-ITVDLTTQESHIARLARDG
Mvan_3871|M.vanbaalenii_PYR-1 --------WADAAADELEATGERARRGGTE-YSALLTSQELRIAQMLGRG
MUL_2033|M.ulcerans_Agy99 DVALPPTELEMAEFEQARERGEQVVAPAPMPFDRATQQRRAKRAERELTE
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 LAAGDEAALLAVSEELTSIGMRAAAADAAAQARRGAAAQPLR--------
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 LSNREVAAELYVSPKTVQYHLTRVYAKLGVRSRAELAALRR---------
MAB_3361|M.abscessus_ATCC_1997 LTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR----------
TH_3225|M.thermoresistible__bu LTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW----
MMAR_0085|M.marinum_M YTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRELRAILMESP------
Mvan_3871|M.vanbaalenii_PYR-1 ATTKEAAAALFLSPKTVEYHLRNVYHKLAISSRSELKAVVQDRADG----
MUL_2033|M.ulcerans_Agy99 LGRVNPLALEEFAALEERYNFLSTQLEDVKAARKDLLDVVADVDARILQV
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 --------------------------------------------------
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mvan_3871|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2033|M.ulcerans_Agy99 FSDAFVDVEREFQIVFSSLFPGGEGRLRLTAPEDMLTTGIEVEARPPGKK
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 --------------------------------------------------
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mvan_3871|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2033|M.ulcerans_Agy99 VSRLSLLSGGEKALTAVAILVAIFRARPSPFYIMDEVEAALDDTNLRRLI
Mb1236c|M.bovis_AF2122/97 --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1348|M.avium_104 --------------------------------------------------
Mflv_1352|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1901|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3225|M.thermoresistible__bu --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mvan_3871|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2033|M.ulcerans_Agy99 GLFEMLRDRSQLIIITHQKPTMEVADALYGVTMQGDGITAVISQRIRGQQ
Mb1236c|M.bovis_AF2122/97 ---------
Rv1204c|M.tuberculosis_H37Rv ---------
MAV_1348|M.avium_104 ---------
Mflv_1352|M.gilvum_PYR-GCK ---------
MSMEG_1901|M.smegmatis_MC2_155 ---------
MAB_3361|M.abscessus_ATCC_1997 ---------
TH_3225|M.thermoresistible__bu ---------
MMAR_0085|M.marinum_M ---------
Mvan_3871|M.vanbaalenii_PYR-1 ---------
MUL_2033|M.ulcerans_Agy99 VDRLVANSS