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M. avium 104 MAV_0578 (-)

annotation: transcriptional regulator, LuxR family protein
coordinates: 559452 - 562085
length: 877

VIGGELLIGRDSELAAIRRALNGADHHRGVVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQAL
PLGAFIGLLGDAMSEPLTSVRRVIETFVARQRRGRVVVGVDDAHLLDGLSALVVHQLAQSGGVRLVVTVR
TGSHQPDAVTALWKDDLLTRLDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLSDQM
AAGRMRRVAGVWMWDGDVAVSASLSDTVGRQLGRLTPPLALVVDTLSQCEPLPVDLLCDLASREDLVAAE
AMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQDADMQATVRRALLTLESDL
DPQPELYLESARHAMTLLDLDLADRLANAAARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGDA
SDRHYWATVRAANLVWMLGRPADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAERARAALD
SESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEASHMRFWFGAVYGRACRLTGRIDEF
VSTARRLADSARDVPGLAYANLALLLGNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASYFALAEA
HGRLGHPAQANEAIAGARSCVPPDFLFMHTGLALATGWALAAGGQLREAVATAQAAARLARDRGQPTHEL
ACIQAAAQWGDAAGAVRARALADALSLPLADAIACHAEALRAGNGEALLTVAAAYRAIGDAAAAADAAAQ
ASAAFVEGQQHQRGRYAAALAGELAEECGGLCTPALRTPAGLKLSGRQRDVIELAVAGLSNRQIAERLVM
SVRTVEGHIYRACQRVGAQSRDELATIIRSRPAGRES
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_0578--100% (877)transcriptional regulator, LuxR family protein
M. avium 104MAV_2362-4e-9732.17% (886) TPR repeat-containing protein
M. avium 104MAV_2364-6e-9531.03% (867) TPR repeat-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1236c-2e-5431.96% (560) hypothetical protein Mb1236c
M. gilvum PYR-GCKMflv_4479-1e-10133.06% (844) regulatory protein, LuxR
M. tuberculosis H37RvRv1204c-2e-5431.96% (560) hypothetical protein Rv1204c
M. leprae Br4923MLBr_01753-9e-0825.79% (411) putative transcriptional regulator
M. abscessus ATCC 19977MAB_3907c-1e-10933.18% (871) LuxR transcriptional regulator
M. marinum MMMAR_4234-4e-3728.60% (542) hypothetical protein MMAR_4234
M. smegmatis MC2 155MSMEG_4205-1e-10933.79% (867) putative transcriptional regulator
M. thermoresistible (build 8)TH_4413-1e-8335.45% (646) PUTATIVE putative response regulator receiver protein
M. ulcerans Agy99MUL_0955-1e-3728.78% (542) hypothetical protein MUL_0955
M. vanbaalenii PYR-1Mvan_0244-1e-13837.54% (871) response regulator receiver protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               --------------------------------------------------
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4205|M.smegmatis_MC2_155      --------------------------------------------------
MAV_0578|M.avium_104                --------------------------------------------------
Mvan_0244|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               --------------------------------------------------
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_3907c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_4205|M.smegmatis_MC2_155      --------------------------------------------------
MAV_0578|M.avium_104                --------------------------------------------------
Mvan_0244|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               -------------------------------------------MPIRWNV
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          ------------------------------------------------MT
MAB_3907c|M.abscessus_ATCC_199      -------------MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPMARSWQL
MSMEG_4205|M.smegmatis_MC2_155      -------------------------------------------MSRQWQL
MAV_0578|M.avium_104                -------------------------------------------MIGGELL
Mvan_0244|M.vanbaalenii_PYR-1       -------------------------------------------MASAWPL
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
                                                                                      

Mb1236c|M.bovis_AF2122/97           ---MRVWKHVEAAVDSPDRCGVVLVG-PHGVGKTLLAQLAAEQVMSEDGR
Rv1204c|M.tuberculosis_H37Rv        ---MRVWKHVEAAVDSPDRCGVVLVG-PHGVGKTLLAQLAAEQVMSEDGR
MMAR_4234|M.marinum_M               PQHAAALEQLDVALSDLARPGAVILG-PDGVGKSTLARLAAEHFAQRHP-
MUL_0955|M.ulcerans_Agy99           ------MEQLDVALSDLARPGAVILG-PDGVGKSTLARLAAEHFAQRHP-
Mflv_4479|M.gilvum_PYR-GCK          AGLGLARTQVESAIVAS-RLRAVLVG-AAGVGKTSMARKLARDYARKHP-
MAB_3907c|M.abscessus_ATCC_199      LDRQTEFGAVRSAMADDSTCGAVLVG-AAGVGKTTLARAVTKSLD-----
MSMEG_4205|M.smegmatis_MC2_155      LDRPDEIDAIRSALESTDTCGVVLVG-AAGVGKTTLARTVTSALT-----
MAV_0578|M.avium_104                IGRDSELAAIRRALNGADHHRGVVIAGAAGVGKTWLARAALRRAG---AS
Mvan_0244|M.vanbaalenii_PYR-1       IGRRHELALTHAAIAESG---AVVLTGAAGVGKSRVAREVLERS-----Q
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
                                                                                      

Mb1236c|M.bovis_AF2122/97           SGRARWVVGTAPGRAIPFG---------------------------AFRH
Rv1204c|M.tuberculosis_H37Rv        SGRARWVVGTAPGRAIPFG---------------------------AFRH
MMAR_4234|M.marinum_M               ATVIRWVTGTPTERTVPFG---------------------------AFSH
MUL_0955|M.ulcerans_Agy99           ATVIRWVTGTPTERAVPLG---------------------------AFSH
Mflv_4479|M.gilvum_PYR-GCK          RLTSHWVSATASARDIPFA---------------------------AFSH
MAB_3907c|M.abscessus_ATCC_199      -ADVRWVACTESSRSIPLG---------------------------VFAH
MSMEG_4205|M.smegmatis_MC2_155      -NKVHWTACTESSRSIPLG---------------------------AFAH
MAV_0578|M.avium_104                GEQIKWIVGTQSAQALPLG---------------------------AFIG
Mvan_0244|M.vanbaalenii_PYR-1       YRIARWIAATQTGRSVPLG---------------------------ALAQ
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
                                                                                      

Mb1236c|M.bovis_AF2122/97           LISLPAS-------------------------GADIGRPAALLRAARSSL
Rv1204c|M.tuberculosis_H37Rv        LISLPAS-------------------------GADIGRPAALLRAARSSL
MMAR_4234|M.marinum_M               LVEI-----------------------------AELGKPAALLRAARASL
MUL_0955|M.ulcerans_Agy99           LVEI-----------------------------AELGKPAALLRAARASL
Mflv_4479|M.gilvum_PYR-GCK          LIDV-----------------------------SGGEEPTTLLRAARESL
MAB_3907c|M.abscessus_ATCC_199      WIQAS-----------------------------GSRDPTALIAAARESI
MSMEG_4205|M.smegmatis_MC2_155      WVGAT-----------------------------ASRDPIALLASARESL
MAV_0578|M.avium_104                LLGDA------------------------------MSEPLTSVRRVIETF
Mvan_0244|M.vanbaalenii_PYR-1       FAGDC------------------------------GPDPLRRVQEVIDAL
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL
                                                                                      

Mb1236c|M.bovis_AF2122/97           TG--DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD
Rv1204c|M.tuberculosis_H37Rv        TG--DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD
MMAR_4234|M.marinum_M               GRKVRQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E
MUL_0955|M.ulcerans_Agy99           GRKVRQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E
Mflv_4479|M.gilvum_PYR-GCK          RS---AHGLLLVVDDAHHLDTLSATLVHQLAVTDNAHIMLTVREGEPVPD
MAB_3907c|M.abscessus_ATCC_199      VS---TANPIIGIDDAHLLDDLSATLLHQIAVDHVGHVVATVRSGEPVPD
MSMEG_4205|M.smegmatis_MC2_155      VA---DGDVVVGVDDAHLLDQLSATLLHQFAVDHAGHVVATVRNGEPVPD
MAV_0578|M.avium_104                VARQRRGRVVVGVDDAHLLDGLSALVVHQLAQSGGVRLVVTVRTGSHQPD
Mvan_0244|M.vanbaalenii_PYR-1       IGDEPPMTVLVCVDDAHLLDEQSAFVVSQLVERRIAPVLMTIRDGEAVPD
TH_4413|M.thermoresistible__bu      ---------------------------------------VVRRSGG----
MLBr_01753|M.leprae_Br4923          RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLG-ACPSLTILATSREPIGV
                                                                                      

Mb1236c|M.bovis_AF2122/97           AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG
Rv1204c|M.tuberculosis_H37Rv        AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG
MMAR_4234|M.marinum_M               AIAALWTDNLLDRIDVAPPD------------------------------
MUL_0955|M.ulcerans_Agy99           AIAALCTDNLLDRIDVAPPD------------------------------
Mflv_4479|M.gilvum_PYR-GCK          AVTALWKDSILSRHDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQG
MAB_3907c|M.abscessus_ATCC_199      AVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRG
MSMEG_4205|M.smegmatis_MC2_155      AVTSLWKDGYLQRFELQPFSKQQSIALIETVLGGTLEGLSADVMWESSGG
MAV_0578|M.avium_104                AVTALWKDDLLTRLDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGG
Mvan_0244|M.vanbaalenii_PYR-1       AIASLCADGRRPRIDIAPLTAGDVTALLESVLDGPLESASVQRFWSYTRG
TH_4413|M.thermoresistible__bu      --------------------------------------------------
MLBr_01753|M.leprae_Br4923          AGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD
                                                                                      

Mb1236c|M.bovis_AF2122/97           NPLYLRHLIDGGG----LEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE
Rv1204c|M.tuberculosis_H37Rv        NPLYLRHLIDGGG----LEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE
MMAR_4234|M.marinum_M               ----------------------------GKTKQS--EPADVDEFIAELPA
MUL_0955|M.ulcerans_Agy99           ----------------------------GQTKQS--EPADVDEFIAELPA
Mflv_4479|M.gilvum_PYR-GCK          NPLYLRHLVDAALGTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLPE
MAB_3907c|M.abscessus_ATCC_199      NPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDD
MSMEG_4205|M.smegmatis_MC2_155      NPLFLRNMVEGAVDAGTLTEVNGVWQFRGPTVIPSGLAELLDDRLAHAGE
MAV_0578|M.avium_104                NTLFLRQLLSDQMAAGRMRRVAGVWMWDGDVAVSASLSDTVGRQLGRLTP
Mvan_0244|M.vanbaalenii_PYR-1       NALHLRQLIADEVAAGRLAQRSGVWIWDGAPRLSPSLVELIGSSIGRLAE
TH_4413|M.thermoresistible__bu      ---------------------------------APGLIALIEERIGLLAE
MLBr_01753|M.leprae_Br4923          GMPLAIELAAARIRTLSLTEIADG--LDDRFRLLTGGARTAVRRQQTLRA
                                                                                      

Mb1236c|M.bovis_AF2122/97           PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPDSDTS
Rv1204c|M.tuberculosis_H37Rv        PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPDSDTS
MMAR_4234|M.marinum_M               PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEPDEPA
MUL_0955|M.ulcerans_Agy99           PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEPDEPA
Mflv_4479|M.gilvum_PYR-GCK          PVRSVLEFLAIDDPLSVDDLAALTG---IDAVDAAETCGVVTITDRAGAL
MAB_3907c|M.abscessus_ATCC_199      TVFSALKVLSMCEPLDIDTLCEIASDEAVDAAEIADLIRVERD---GVRT
MSMEG_4205|M.smegmatis_MC2_155      DVMNALKLLSLCEPLDIDAFAELAGEEAVDSAEMRGLIRIVTDA--GGTL
MAV_0578|M.avium_104                PLALVVDTLSQCEPLPVDLLCDLAS---REDLVAAEAMGLVTVERTPRAL
Mvan_0244|M.vanbaalenii_PYR-1       SVIDVIDVLAVCDPVELTVLHGLAG---ASELGAAAEHGLVAVDQVAG--
TH_4413|M.thermoresistible__bu      PVGDVVDILAVGEPVDLGLLTRLTD---PAAVEEADVRGLIAIEDGDR-A
MLBr_01753|M.leprae_Br4923          SMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRL
                                            *:  :      :  : .                         

Mb1236c|M.bovis_AF2122/97           EIFVGHPLYADRARAV-LTAEHAHALRVSLVAQLAKHPSDH-VSDQLRLS
Rv1204c|M.tuberculosis_H37Rv        EIFVGHPLYADRARAV-LTAEHAHALRVSLVAQLAKHPSDH-VSDQLRLS
MMAR_4234|M.marinum_M               VVYTAHPLFAKRARVA-LGDDGARQRRTELVTLLSQHPNEH-LSDRLRLA
MUL_0955|M.ulcerans_Agy99           VVYTAHPLFAKRARVA-LGDDGARQRRTELVTLLSQHPNEH-LSDRLRLA
Mflv_4479|M.gilvum_PYR-GCK          YAHPFHPIYTERVRSS-LGLLAMRRLRKLLAGRMSVRAPGN-LSTRLRMA
MAB_3907c|M.abscessus_ATCC_199      VVRFSHPMFGEAVRRR-VGTASGRRLRGKLVRVLRDRDLGT-ASNRIRLA
MSMEG_4205|M.smegmatis_MC2_155      TARFAHPLFAEVVRRR-VGTASARKLRGRIAKILRDRDLST-AASRIRLA
MAV_0578|M.avium_104                MARLAHPLFGELRRAG-AGEMYLSTIRGRLATRLAQDQDAD-MQATVRRA
Mvan_0244|M.vanbaalenii_PYR-1       LVHLAHPLFGEVRRDQ-AGTARLRNLRRQVADAIGMLPSQS-PVQLVRRG
TH_4413|M.thermoresistible__bu      LVRLAHPLYGEVRRRR-AAVTRLRRLRGLVADELAQAADADDLAQVVRRT
MLBr_01753|M.leprae_Br4923          TMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDH
                                         :.:     *            *      :             *  

Mb1236c|M.bovis_AF2122/97           SLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALDRSDALAA
Rv1204c|M.tuberculosis_H37Rv        SLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALDRSDALAA
MMAR_4234|M.marinum_M               SLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALDRSGGLQA
MUL_0955|M.ulcerans_Agy99           SLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALDRSGGLQA
Mflv_4479|M.gilvum_PYR-GCK          ALAMGTDEPPS---ADELVGLSWEAMRLGDLALGERLARAALDQADGLAA
MAB_3907c|M.abscessus_ATCC_199      RLSIDCDEPVD---VDLLVTAAKDAVYLSNLPLGEELARAAVDGGGGLQA
MSMEG_4205|M.smegmatis_MC2_155      QLCIESDRGAD---VDLLITAAKDAVFLSNLPLGEQLARAAFDHGGGLPA
MAV_0578|M.avium_104                LLTLESDLDPQ---PELYLESARHAMTLLDLDLADRLANAAARAGAPGAA
Mvan_0244|M.vanbaalenii_PYR-1       VLAMDADGNRD---PELLRSAAEAALQLLDLDLAVQLSRCAVQAGGGRAA
TH_4413|M.thermoresistible__bu      TLLLDSDRRPD---VDLFVRAARGAARIGDLPLAERLSGAAVRAGATVEA
MLBr_01753|M.leprae_Br4923          YMALGALLDTPG-DIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQL
                                     : :                       : ::  .   :  :   .     

Mb1236c|M.bovis_AF2122/97           RLPLAYALGWQGRGRE----ADAVLAAVNPAELT-ETELMAWAIPRAANR
Rv1204c|M.tuberculosis_H37Rv        RLPLAYALGWQGRGRE----ADAVLAAVNPAELT-ETELMAWAIPRAANR
MMAR_4234|M.marinum_M               RLVLGQALAWRGRGRE----AGQVLTAVDPGQLS-EAELMAWAVPQAANQ
MUL_0955|M.ulcerans_Agy99           RLVLGQALAWRGRGRE----AGQVLTAVDPGQLS-EAELMAWAVPQAANQ
Mflv_4479|M.gilvum_PYR-GCK          RLPLAHSLSWQGRGRD----ADDVLNPVDPDTLT-QWDLMAWTLPKAANR
MAB_3907c|M.abscessus_ATCC_199      AAMLSRSLLWQGRPEQ----AEEILAAFDPDDLD-ELSLVLWGIPRISIA
MSMEG_4205|M.smegmatis_MC2_155      ATLLSRALLWQGHPAQ----ADNILARFPPDHMD-EMELVQWGIPRLSIL
MAV_0578|M.avium_104                GVR-AMNLVLLGRGEQ----AEEALRAITDGADGDASDRHYWATVRAANL
Mvan_0244|M.vanbaalenii_PYR-1       QLTHALALGMVGGGSG----CDDMLAALMATAEG--GELAQIALMRAAIL
TH_4413|M.thermoresistible__bu      AIVHARALTWLGRGDQ----AETVLAAIDVADHT------RLAFMRASNM
MLBr_01753|M.leprae_Br4923          ASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVML
                                               *            :                    .    

Mb1236c|M.bovis_AF2122/97           FWMLNE-PERATAFLQTTRSRVTEPTARSTLDALAATFAMN------SGN
Rv1204c|M.tuberculosis_H37Rv        FWMLNE-PERATAFLQTTRSRVTEPTARSTLDALAATFAMN------SGN
MMAR_4234|M.marinum_M               FWMLGE-PERATAFLQTTRNRVTDLTARTTLDALTATFAMN------SGN
MUL_0955|M.ulcerans_Agy99           FWMLGE-PERATAFLQTTRNRVTDLTARTTLDALTATFAMN------SGN
Mflv_4479|M.gilvum_PYR-GCK          FWMLSE-SEEAVEYLRQMRARITERGALHTIDALAATFAMN------AGD
MAB_3907c|M.abscessus_ATCC_199      FWSMGE-NERAHELLALLHERVRHHILKPVVDATDAAIALH------ENR
MSMEG_4205|M.smegmatis_MC2_155      FWSMGD-VPLAHQVLGELNSRVTHPILQLIIDATEAGMAVH------ENR
MAV_0578|M.avium_104                VWMLGR-PADAALVLDGLAARPETPAQAAARCAVQACLDAV------AAR
Mvan_0244|M.vanbaalenii_PYR-1       TWNMGK-PHTAEAVLDSASEAAAGCGLAPSCDALRASIWAQ------LGR
TH_4413|M.thermoresistible__bu      LWALSD-PEGAKRLIG-QAAAGMPADQRAHLDAFCAVHAAA------MGQ
MLBr_01753|M.leprae_Br4923          HAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTE
                                       :      .   :                 .                 

Mb1236c|M.bovis_AF2122/97           LPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGR---FGDVDRLAE
Rv1204c|M.tuberculosis_H37Rv        LPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGR---FGDVDRLAE
MMAR_4234|M.marinum_M               VPRAITLATEVLAEPSADDTAIAWAASAAALASARMGR---FADVPQLAQ
MUL_0955|M.ulcerans_Agy99           VPRAITLATEVLAEPSADDTAIAWAASAAALASARMGR---FADVPQLAQ
Mflv_4479|M.gilvum_PYR-GCK          PAEAVTVAKGILAADDAQDLAVAWASAAATLSSARMGR---FAEVDGLAQ
MAB_3907c|M.abscessus_ATCC_199      FDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFEPIAQRCR
MSMEG_4205|M.smegmatis_MC2_155      ITEGLAIAERVLDHPECPRQATDFAAFACGLAMPVAGRGEAFLPIASRCR
MAV_0578|M.avium_104                CQLAAERARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQAL
Mvan_0244|M.vanbaalenii_PYR-1       PQAAVELAGTALAGNAVQPLAAMFGIWALVIGHGDLGDVDHLREAAARGY
TH_4413|M.thermoresistible__bu      PDEVFRHAG-AVVVDELPGIIGAETAWALTLAAGEAGRTAEAVAAADTGY
MLBr_01753|M.leprae_Br4923          VARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAAD
                                               :                  :     *             

Mb1236c|M.bovis_AF2122/97           RASAAEHPG-LLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA------
Rv1204c|M.tuberculosis_H37Rv        RASAAEHPG-LLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA------
MMAR_4234|M.marinum_M               RASEAEHPG-LLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFAEL-QQP
MUL_0955|M.ulcerans_Agy99           RASEAEHPG-LLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFAEL-QQP
Mflv_4479|M.gilvum_PYR-GCK          RGLDAAHPG-LLRFTLGLGQTLALIMNADVASAEHLARHYLSFSEF-QQP
MAB_3907c|M.abscessus_ATCC_199      DDKKRTTDG-LIAAMVRYCDVLALTYTGQLDLAEERVAEYTKFSSAGQFL
MSMEG_4205|M.smegmatis_MC2_155      -AQRKTTDG-MIRIMVFYGEVLALAYTGQFDLARQRAEEYAEFSSAGQFA
MAV_0578|M.avium_104                RRATTSFEASHMRFWFGAVYGRACRLTGRIDEFVSTARRLADSARDVPGL
Mvan_0244|M.vanbaalenii_PYR-1       DLALSAPEASQLRFSLGLMEIVGLRLAGALESARSVAARLRGQSQDVD-V
TH_4413|M.thermoresistible__bu      RLTARFSDAAYTRFTLTDAHVTALILAGRIAAAVDTATVLDRQVGDLPGG
MLBr_01753|M.leprae_Br4923          DLAQEIGDR-FVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDT
                                                               . .                    

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               GRAIGEVLLAHVLIVKGEFGAAAAMLEPAAA----ELERTG-YSWGPLSL
MUL_0955|M.ulcerans_Agy99           GRAIGEVLLAHVLIVKGEFGTAAAMVEPAAA----ELERTG-YSWGPLSL
Mflv_4479|M.gilvum_PYR-GCK          GRAIGEVLLGHTLLASGRFGDAVTLLRQAAA----ALTYTG-YSWGPLAL
MAB_3907c|M.abscessus_ATCC_199      AWAIARIMAGVVATQRGLFREAIEAFEQALA----AQRADRPLPWQLPAR
MSMEG_4205|M.smegmatis_MC2_155      GWAIAKIMAGAAAMHSGRFRDAISAIEQALA----ALNAEISLPWQLPGR
MAV_0578|M.avium_104                AYANLALLLGNAELARGAAAEAARLVQEALA-GAQIHEVT--SGLRPASY
Mvan_0244|M.vanbaalenii_PYR-1       SHAVTAMLTGLSELCCGDLISAQRWFRESLARAAKFPDLS--VSVCELSG
TH_4413|M.thermoresistible__bu      TALLARGVAGRAALAAGRLDDAVAWLRDVVSVLFSADTAGGFYGFGYRYQ
MLBr_01753|M.leprae_Br4923          VTRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVF
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               MLLAT-AIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKATV
MUL_0955|M.ulcerans_Agy99           MLLAT-AIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKATV
Mflv_4479|M.gilvum_PYR-GCK          TGLAQ-ALGQQGRAADASAVLTRAEASHGMRSALYAPDLALARAWTLAAA
MAB_3907c|M.abscessus_ATCC_199      LLLAR-AYAALGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLVAAR
MSMEG_4205|M.smegmatis_MC2_155      LLLAR-AYAAVGEVIEAERVLDDAMEHSGAFMALHEPQRTLAKACVAAAK
MAV_0578|M.avium_104                FALAE-AHGRLGHPAQANEAIAGARSCVPPDFLFMHTGLALATGWALAAG
Mvan_0244|M.vanbaalenii_PYR-1       LWLTT-ALAMSGNRAAAQDVYDQTLKTFDGEIVLWQSEARLAQAWLHAAN
TH_4413|M.thermoresistible__bu      HPYAT-ALAVLGHTAAAATALATLDEREFPSWRYLDHERTIALAWLRAAQ
MLBr_01753|M.leprae_Br4923          AALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVAR
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               RDQAGALFDTR----EAARAAERGKQSAVALCVWHDAVRLGDTRALAPVT
MUL_0955|M.ulcerans_Agy99           RDQAGALFDTR----EAARAAERGKQSAVALCVWHDAVRLGDTRALAPVT
Mflv_4479|M.gilvum_PYR-GCK          RDLRGAVASAR----DAVHAAVQSGQDAVALRALQDCARLGDTHGLATAV
MAB_3907c|M.abscessus_ATCC_199      GSDRGAVDAAR----RAADAAHSAGQYALEAEALHHAARFGDRTVGRRIE
MSMEG_4205|M.smegmatis_MC2_155      GAHRSAIDIAR----SAADLARSSEQHAVEAEALHHCARFGDRTVARRLQ
MAV_0578|M.avium_104                GQLREAVATAQ----AAARLARDRGQPTHELACIQAAAQWGDAAGAVRAR
Mvan_0244|M.vanbaalenii_PYR-1       GSTSLAVAFAI----DAARAARKHGRPAREVVCLQAATQFGSTSSADRLR
TH_4413|M.thermoresistible__bu      GAVSTSIQRLR----AEAESARTAGRFAVELLCLQTAVQFGDRTCGPRLH
MLBr_01753|M.leprae_Br4923          RLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQ
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               RLAAEIDCKVGNIVVRHARALADNDAGALASVADELAAIGMHAAAADAAA
MUL_0955|M.ulcerans_Agy99           RLAAEIDCKVGNIVVRHARALANNDAGALASVADELAAIGMHAAAADAAA
Mflv_4479|M.gilvum_PYR-GCK          RLSDRIGCVTGPLCVAHLRALAAGDGAALDAVSADLETAGLPAAAADAAA
MAB_3907c|M.abscessus_ATCC_199      SLCTRVHGPLTGLYARHALAVAHSDITGLEAVSADFEAAGLLLSAADAAA
MSMEG_4205|M.smegmatis_MC2_155      GLVDRVDGPLARLYAQHAAAVAAADPVALDAVSSAFEQAGLMLSAADAAA
MAV_0578|M.avium_104                ALADALSLPLADAIACHAEALRAGNGEALLTVAAAYRAIGDAAAAADAAA
Mvan_0244|M.vanbaalenii_PYR-1       ELSSAVRGPRADAAYAHARALRKADGHGLLAAVGRYEAFGDRVAAVDAAA
TH_4413|M.thermoresistible__bu      QLEDRVDGPRVAVAARFADALHTGDGSGLRSIADEFEDMGDMVAAADAAA
MLBr_01753|M.leprae_Br4923          ASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAG
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               QAERAGGR------------------------------------------
MUL_0955|M.ulcerans_Agy99           QAERAGGR------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          QATFAHQRRGDRAGEVASRSRASRLSQVCGAPATPALEQVLNPMP-----
MAB_3907c|M.abscessus_ATCC_199      QAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKPLP-----
MSMEG_4205|M.smegmatis_MC2_155      QAVLLHDKAGHRRQSTESAAHALQLAGRCGGAATPAIRAAARPLP-----
MAV_0578|M.avium_104                QASAAFVEGQQHQRGRYAAALAGELAEECGGLCTPALR-TPAGLK-----
Mvan_0244|M.vanbaalenii_PYR-1       QAAVVLDKRGQREASIAAAATARRLATESGADTVTFRS-MRCSAV-----
TH_4413|M.thermoresistible__bu      HAAIAHRRRGLRGSALACSAHAQGLAERCGGAHTPALRRAAEDLP-----
MLBr_01753|M.leprae_Br4923          YESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGW
                                                                                      

Mb1236c|M.bovis_AF2122/97           --------------------------------------------------
Rv1204c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_4234|M.marinum_M               --------------------------------------------------
MUL_0955|M.ulcerans_Agy99           --------------------------------------------------
Mflv_4479|M.gilvum_PYR-GCK          --LTGREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRACMKFGVPDR
MAB_3907c|M.abscessus_ATCC_199      --ISSREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDR
MSMEG_4205|M.smegmatis_MC2_155      --VTAREREVAALVAQGLLNREIAERLTVSVRTVEGHIYRACIKLGVADR
MAV_0578|M.avium_104                --LSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSR
Mvan_0244|M.vanbaalenii_PYR-1       --LTRRQREVIALAASGLSNREIADRLVTSVRTVESHFLRACRNTGTNTR
TH_4413|M.thermoresistible__bu      --LTDREREIVLLLGAGLTNREIADTLTLSVRTVENHIYKSMLKTGTSSR
MLBr_01753|M.leprae_Br4923          ESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSR
                                                                                      

Mb1236c|M.bovis_AF2122/97           ---------------------------
Rv1204c|M.tuberculosis_H37Rv        ---------------------------
MMAR_4234|M.marinum_M               ---------------------------
MUL_0955|M.ulcerans_Agy99           ---------------------------
Mflv_4479|M.gilvum_PYR-GCK          AALASTVGGMHGREGTA----------
MAB_3907c|M.abscessus_ATCC_199      EEFAKIVGSDLKPPEAS----------
MSMEG_4205|M.smegmatis_MC2_155      DELARMIWTDLTPLEADPR--------
MAV_0578|M.avium_104                DELATIIRSRPAGRES-----------
Mvan_0244|M.vanbaalenii_PYR-1       DELIAFLLGDDRAPS------------
TH_4413|M.thermoresistible__bu      DELAALLPRSPRPSDPRRAPRSPRRID
MLBr_01753|M.leprae_Br4923          VQLVQEAARHN----------------