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VIGGELLIGRDSELAAIRRALNGADHHRGVVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQAL PLGAFIGLLGDAMSEPLTSVRRVIETFVARQRRGRVVVGVDDAHLLDGLSALVVHQLAQSGGVRLVVTVR TGSHQPDAVTALWKDDLLTRLDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLSDQM AAGRMRRVAGVWMWDGDVAVSASLSDTVGRQLGRLTPPLALVVDTLSQCEPLPVDLLCDLASREDLVAAE AMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQDQDADMQATVRRALLTLESDL DPQPELYLESARHAMTLLDLDLADRLANAAARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGDA SDRHYWATVRAANLVWMLGRPADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAERARAALD SESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEASHMRFWFGAVYGRACRLTGRIDEF VSTARRLADSARDVPGLAYANLALLLGNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASYFALAEA HGRLGHPAQANEAIAGARSCVPPDFLFMHTGLALATGWALAAGGQLREAVATAQAAARLARDRGQPTHEL ACIQAAAQWGDAAGAVRARALADALSLPLADAIACHAEALRAGNGEALLTVAAAYRAIGDAAAAADAAAQ ASAAFVEGQQHQRGRYAAALAGELAEECGGLCTPALRTPAGLKLSGRQRDVIELAVAGLSNRQIAERLVM SVRTVEGHIYRACQRVGAQSRDELATIIRSRPAGRES
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0578 | - | - | 100% (877) | transcriptional regulator, LuxR family protein |
M. avium 104 | MAV_2362 | - | 4e-97 | 32.17% (886) | TPR repeat-containing protein |
M. avium 104 | MAV_2364 | - | 6e-95 | 31.03% (867) | TPR repeat-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1236c | - | 2e-54 | 31.96% (560) | hypothetical protein Mb1236c |
M. gilvum PYR-GCK | Mflv_4479 | - | 1e-101 | 33.06% (844) | regulatory protein, LuxR |
M. tuberculosis H37Rv | Rv1204c | - | 2e-54 | 31.96% (560) | hypothetical protein Rv1204c |
M. leprae Br4923 | MLBr_01753 | - | 9e-08 | 25.79% (411) | putative transcriptional regulator |
M. abscessus ATCC 19977 | MAB_3907c | - | 1e-109 | 33.18% (871) | LuxR transcriptional regulator |
M. marinum M | MMAR_4234 | - | 4e-37 | 28.60% (542) | hypothetical protein MMAR_4234 |
M. smegmatis MC2 155 | MSMEG_4205 | - | 1e-109 | 33.79% (867) | putative transcriptional regulator |
M. thermoresistible (build 8) | TH_4413 | - | 1e-83 | 35.45% (646) | PUTATIVE putative response regulator receiver protein |
M. ulcerans Agy99 | MUL_0955 | - | 1e-37 | 28.78% (542) | hypothetical protein MUL_0955 |
M. vanbaalenii PYR-1 | Mvan_0244 | - | 1e-138 | 37.54% (871) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M -------------------------------------------------- MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK -------------------------------------------------- MAB_3907c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4205|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0578|M.avium_104 -------------------------------------------------- Mvan_0244|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M -------------------------------------------------- MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK -------------------------------------------------- MAB_3907c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_4205|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0578|M.avium_104 -------------------------------------------------- Mvan_0244|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M -------------------------------------------MPIRWNV MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK ------------------------------------------------MT MAB_3907c|M.abscessus_ATCC_199 -------------MTTTTGTIDGRGQAPRLSPAKVHPDLHSYPMARSWQL MSMEG_4205|M.smegmatis_MC2_155 -------------------------------------------MSRQWQL MAV_0578|M.avium_104 -------------------------------------------MIGGELL Mvan_0244|M.vanbaalenii_PYR-1 -------------------------------------------MASAWPL TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL Mb1236c|M.bovis_AF2122/97 ---MRVWKHVEAAVDSPDRCGVVLVG-PHGVGKTLLAQLAAEQVMSEDGR Rv1204c|M.tuberculosis_H37Rv ---MRVWKHVEAAVDSPDRCGVVLVG-PHGVGKTLLAQLAAEQVMSEDGR MMAR_4234|M.marinum_M PQHAAALEQLDVALSDLARPGAVILG-PDGVGKSTLARLAAEHFAQRHP- MUL_0955|M.ulcerans_Agy99 ------MEQLDVALSDLARPGAVILG-PDGVGKSTLARLAAEHFAQRHP- Mflv_4479|M.gilvum_PYR-GCK AGLGLARTQVESAIVAS-RLRAVLVG-AAGVGKTSMARKLARDYARKHP- MAB_3907c|M.abscessus_ATCC_199 LDRQTEFGAVRSAMADDSTCGAVLVG-AAGVGKTTLARAVTKSLD----- MSMEG_4205|M.smegmatis_MC2_155 LDRPDEIDAIRSALESTDTCGVVLVG-AAGVGKTTLARTVTSALT----- MAV_0578|M.avium_104 IGRDSELAAIRRALNGADHHRGVVIAGAAGVGKTWLARAALRRAG---AS Mvan_0244|M.vanbaalenii_PYR-1 IGRRHELALTHAAIAESG---AVVLTGAAGVGKSRVAREVLERS-----Q TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC Mb1236c|M.bovis_AF2122/97 SGRARWVVGTAPGRAIPFG---------------------------AFRH Rv1204c|M.tuberculosis_H37Rv SGRARWVVGTAPGRAIPFG---------------------------AFRH MMAR_4234|M.marinum_M ATVIRWVTGTPTERTVPFG---------------------------AFSH MUL_0955|M.ulcerans_Agy99 ATVIRWVTGTPTERAVPLG---------------------------AFSH Mflv_4479|M.gilvum_PYR-GCK RLTSHWVSATASARDIPFA---------------------------AFSH MAB_3907c|M.abscessus_ATCC_199 -ADVRWVACTESSRSIPLG---------------------------VFAH MSMEG_4205|M.smegmatis_MC2_155 -NKVHWTACTESSRSIPLG---------------------------AFAH MAV_0578|M.avium_104 GEQIKWIVGTQSAQALPLG---------------------------AFIG Mvan_0244|M.vanbaalenii_PYR-1 YRIARWIAATQTGRSVPLG---------------------------ALAQ TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT Mb1236c|M.bovis_AF2122/97 LISLPAS-------------------------GADIGRPAALLRAARSSL Rv1204c|M.tuberculosis_H37Rv LISLPAS-------------------------GADIGRPAALLRAARSSL MMAR_4234|M.marinum_M LVEI-----------------------------AELGKPAALLRAARASL MUL_0955|M.ulcerans_Agy99 LVEI-----------------------------AELGKPAALLRAARASL Mflv_4479|M.gilvum_PYR-GCK LIDV-----------------------------SGGEEPTTLLRAARESL MAB_3907c|M.abscessus_ATCC_199 WIQAS-----------------------------GSRDPTALIAAARESI MSMEG_4205|M.smegmatis_MC2_155 WVGAT-----------------------------ASRDPIALLASARESL MAV_0578|M.avium_104 LLGDA------------------------------MSEPLTSVRRVIETF Mvan_0244|M.vanbaalenii_PYR-1 FAGDC------------------------------GPDPLRRVQEVIDAL TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPITVLDNL Mb1236c|M.bovis_AF2122/97 TG--DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD Rv1204c|M.tuberculosis_H37Rv TG--DAGDLLLVVDDAHNLDPLSATLVYQLARAGAARLVVTVASEAEPPD MMAR_4234|M.marinum_M GRKVRQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E MUL_0955|M.ulcerans_Agy99 GRKVRQGELLLIVDDAHDLDILSATLVYQLALAGAARMIVTARAEVAP-E Mflv_4479|M.gilvum_PYR-GCK RS---AHGLLLVVDDAHHLDTLSATLVHQLAVTDNAHIMLTVREGEPVPD MAB_3907c|M.abscessus_ATCC_199 VS---TANPIIGIDDAHLLDDLSATLLHQIAVDHVGHVVATVRSGEPVPD MSMEG_4205|M.smegmatis_MC2_155 VA---DGDVVVGVDDAHLLDQLSATLLHQFAVDHAGHVVATVRNGEPVPD MAV_0578|M.avium_104 VARQRRGRVVVGVDDAHLLDGLSALVVHQLAQSGGVRLVVTVRTGSHQPD Mvan_0244|M.vanbaalenii_PYR-1 IGDEPPMTVLVCVDDAHLLDEQSAFVVSQLVERRIAPVLMTIRDGEAVPD TH_4413|M.thermoresistible__bu ---------------------------------------VVRRSGG---- MLBr_01753|M.leprae_Br4923 RRCIGDRRMLMVLDNCEYLLDVCANVMTTLLG-ACPSLTILATSREPIGV Mb1236c|M.bovis_AF2122/97 AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG Rv1204c|M.tuberculosis_H37Rv AIAALWSDDLLTRVAIEPLDRAQTAAFVESALDATLDVADADELFRRSLG MMAR_4234|M.marinum_M AIAALWTDNLLDRIDVAPPD------------------------------ MUL_0955|M.ulcerans_Agy99 AIAALCTDNLLDRIDVAPPD------------------------------ Mflv_4479|M.gilvum_PYR-GCK AVTALWKDSILSRHDIAPFDRRESGLLLEQILGGTVEDVSTVRMFEISQG MAB_3907c|M.abscessus_ATCC_199 AVTALWKDNYLQRFELDPLTQRQSIALVEKVLGGPLEGLSADVMWRSSRG MSMEG_4205|M.smegmatis_MC2_155 AVTSLWKDGYLQRFELQPFSKQQSIALIETVLGGTLEGLSADVMWESSGG MAV_0578|M.avium_104 AVTALWKDDLLTRLDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGG Mvan_0244|M.vanbaalenii_PYR-1 AIASLCADGRRPRIDIAPLTAGDVTALLESVLDGPLESASVQRFWSYTRG TH_4413|M.thermoresistible__bu -------------------------------------------------- MLBr_01753|M.leprae_Br4923 AGEVIWRVSMLSPADEAVELFTERAALVQPGFSVTDGNRQIVTEICQRLD Mb1236c|M.bovis_AF2122/97 NPLYLRHLIDGGG----LEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE Rv1204c|M.tuberculosis_H37Rv NPLYLRHLIDGGG----LEHVDGRWRCRDEDRRP--LSGVIDEYLCALPE MMAR_4234|M.marinum_M ----------------------------GKTKQS--EPADVDEFIAELPA MUL_0955|M.ulcerans_Agy99 ----------------------------GQTKQS--EPADVDEFIAELPA Mflv_4479|M.gilvum_PYR-GCK NPLYLRHLVDAALGTGSLRQVEGVWQLRGEMTLSPQLTTLIDAHLTNLPE MAB_3907c|M.abscessus_ATCC_199 NPLFLRHLVEGSMQAGSLTEVNGVWQLRGDAVVPSGLDTLIGDRLEHVDD MSMEG_4205|M.smegmatis_MC2_155 NPLFLRNMVEGAVDAGTLTEVNGVWQFRGPTVIPSGLAELLDDRLAHAGE MAV_0578|M.avium_104 NTLFLRQLLSDQMAAGRMRRVAGVWMWDGDVAVSASLSDTVGRQLGRLTP Mvan_0244|M.vanbaalenii_PYR-1 NALHLRQLIADEVAAGRLAQRSGVWIWDGAPRLSPSLVELIGSSIGRLAE TH_4413|M.thermoresistible__bu ---------------------------------APGLIALIEERIGLLAE MLBr_01753|M.leprae_Br4923 GMPLAIELAAARIRTLSLTEIADG--LDDRFRLLTGGARTAVRRQQTLRA Mb1236c|M.bovis_AF2122/97 PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPDSDTS Rv1204c|M.tuberculosis_H37Rv PARAVVDYLAIAEPLARTDLVALVGGEQLDTLGQAEAAGAVRVGPDSDTS MMAR_4234|M.marinum_M PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEPDEPA MUL_0955|M.ulcerans_Agy99 PARAVLDYLTVEEPLSLADLTVLAGEGAVQQAVELGAAETRVRGEPDEPA Mflv_4479|M.gilvum_PYR-GCK PVRSVLEFLAIDDPLSVDDLAALTG---IDAVDAAETCGVVTITDRAGAL MAB_3907c|M.abscessus_ATCC_199 TVFSALKVLSMCEPLDIDTLCEIASDEAVDAAEIADLIRVERD---GVRT MSMEG_4205|M.smegmatis_MC2_155 DVMNALKLLSLCEPLDIDAFAELAGEEAVDSAEMRGLIRIVTDA--GGTL MAV_0578|M.avium_104 PLALVVDTLSQCEPLPVDLLCDLAS---REDLVAAEAMGLVTVERTPRAL Mvan_0244|M.vanbaalenii_PYR-1 SVIDVIDVLAVCDPVELTVLHGLAG---ASELGAAAEHGLVAVDQVAG-- TH_4413|M.thermoresistible__bu PVGDVVDILAVGEPVDLGLLTRLTD---PAAVEEADVRGLIAIEDGDR-A MLBr_01753|M.leprae_Br4923 SMDWSYALLTESERALFRRLSAISGTFDLKVAYAVGHDDLEEPDQVFDRL *: : : : . Mb1236c|M.bovis_AF2122/97 EIFVGHPLYADRARAV-LTAEHAHALRVSLVAQLAKHPSDH-VSDQLRLS Rv1204c|M.tuberculosis_H37Rv EIFVGHPLYADRARAV-LTAEHAHALRVSLVAQLAKHPSDH-VSDQLRLS MMAR_4234|M.marinum_M VVYTAHPLFAKRARVA-LGDDGARQRRTELVTLLSQHPNEH-LSDRLRLA MUL_0955|M.ulcerans_Agy99 VVYTAHPLFAKRARVA-LGDDGARQRRTELVTLLSQHPNEH-LSDRLRLA Mflv_4479|M.gilvum_PYR-GCK YAHPFHPIYTERVRSS-LGLLAMRRLRKLLAGRMSVRAPGN-LSTRLRMA MAB_3907c|M.abscessus_ATCC_199 VVRFSHPMFGEAVRRR-VGTASGRRLRGKLVRVLRDRDLGT-ASNRIRLA MSMEG_4205|M.smegmatis_MC2_155 TARFAHPLFAEVVRRR-VGTASARKLRGRIAKILRDRDLST-AASRIRLA MAV_0578|M.avium_104 MARLAHPLFGELRRAG-AGEMYLSTIRGRLATRLAQDQDAD-MQATVRRA Mvan_0244|M.vanbaalenii_PYR-1 LVHLAHPLFGEVRRDQ-AGTARLRNLRRQVADAIGMLPSQS-PVQLVRRG TH_4413|M.thermoresistible__bu LVRLAHPLYGEVRRRR-AAVTRLRRLRGLVADELAQAADADDLAQVVRRT MLBr_01753|M.leprae_Br4923 TMLIDKSLVIVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDH :.: * * : * Mb1236c|M.bovis_AF2122/97 SLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALDRSDALAA Rv1204c|M.tuberculosis_H37Rv SLAIDVPASATPAAVTDAATAAGQALRLGDVRLAERLARAALDRSDALAA MMAR_4234|M.marinum_M SLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALDRSGGLQA MUL_0955|M.ulcerans_Agy99 SLALDTDALQP---VDDVVESAEQALRLGDLTLAERLAQAALDRSGGLQA Mflv_4479|M.gilvum_PYR-GCK ALAMGTDEPPS---ADELVGLSWEAMRLGDLALGERLARAALDQADGLAA MAB_3907c|M.abscessus_ATCC_199 RLSIDCDEPVD---VDLLVTAAKDAVYLSNLPLGEELARAAVDGGGGLQA MSMEG_4205|M.smegmatis_MC2_155 QLCIESDRGAD---VDLLITAAKDAVFLSNLPLGEQLARAAFDHGGGLPA MAV_0578|M.avium_104 LLTLESDLDPQ---PELYLESARHAMTLLDLDLADRLANAAARAGAPGAA Mvan_0244|M.vanbaalenii_PYR-1 VLAMDADGNRD---PELLRSAAEAALQLLDLDLAVQLSRCAVQAGGGRAA TH_4413|M.thermoresistible__bu TLLLDSDRRPD---VDLFVRAARGAARIGDLPLAERLSGAAVRAGATVEA MLBr_01753|M.leprae_Br4923 YMALGALLDTPG-DIDHEQLVEQVETELDNLRSAFAWSRETGDIAGALQL : : : :: . : : . Mb1236c|M.bovis_AF2122/97 RLPLAYALGWQGRGRE----ADAVLAAVNPAELT-ETELMAWAIPRAANR Rv1204c|M.tuberculosis_H37Rv RLPLAYALGWQGRGRE----ADAVLAAVNPAELT-ETELMAWAIPRAANR MMAR_4234|M.marinum_M RLVLGQALAWRGRGRE----AGQVLTAVDPGQLS-EAELMAWAVPQAANQ MUL_0955|M.ulcerans_Agy99 RLVLGQALAWRGRGRE----AGQVLTAVDPGQLS-EAELMAWAVPQAANQ Mflv_4479|M.gilvum_PYR-GCK RLPLAHSLSWQGRGRD----ADDVLNPVDPDTLT-QWDLMAWTLPKAANR MAB_3907c|M.abscessus_ATCC_199 AAMLSRSLLWQGRPEQ----AEEILAAFDPDDLD-ELSLVLWGIPRISIA MSMEG_4205|M.smegmatis_MC2_155 ATLLSRALLWQGHPAQ----ADNILARFPPDHMD-EMELVQWGIPRLSIL MAV_0578|M.avium_104 GVR-AMNLVLLGRGEQ----AEEALRAITDGADGDASDRHYWATVRAANL Mvan_0244|M.vanbaalenii_PYR-1 QLTHALALGMVGGGSG----CDDMLAALMATAEG--GELAQIALMRAAIL TH_4413|M.thermoresistible__bu AIVHARALTWLGRGDQ----AETVLAAIDVADHT------RLAFMRASNM MLBr_01753|M.leprae_Br4923 ASSLQPIWFGRGHMYEGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVML * : . Mb1236c|M.bovis_AF2122/97 FWMLNE-PERATAFLQTTRSRVTEPTARSTLDALAATFAMN------SGN Rv1204c|M.tuberculosis_H37Rv FWMLNE-PERATAFLQTTRSRVTEPTARSTLDALAATFAMN------SGN MMAR_4234|M.marinum_M FWMLGE-PERATAFLQTTRNRVTDLTARTTLDALTATFAMN------SGN MUL_0955|M.ulcerans_Agy99 FWMLGE-PERATAFLQTTRNRVTDLTARTTLDALTATFAMN------SGN Mflv_4479|M.gilvum_PYR-GCK FWMLSE-SEEAVEYLRQMRARITERGALHTIDALAATFAMN------AGD MAB_3907c|M.abscessus_ATCC_199 FWSMGE-NERAHELLALLHERVRHHILKPVVDATDAAIALH------ENR MSMEG_4205|M.smegmatis_MC2_155 FWSMGD-VPLAHQVLGELNSRVTHPILQLIIDATEAGMAVH------ENR MAV_0578|M.avium_104 VWMLGR-PADAALVLDGLAARPETPAQAAARCAVQACLDAV------AAR Mvan_0244|M.vanbaalenii_PYR-1 TWNMGK-PHTAEAVLDSASEAAAGCGLAPSCDALRASIWAQ------LGR TH_4413|M.thermoresistible__bu LWALSD-PEGAKRLIG-QAAAGMPADQRAHLDAFCAVHAAA------MGQ MLBr_01753|M.leprae_Br4923 HAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTE : . : . Mb1236c|M.bovis_AF2122/97 LPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGR---FGDVDRLAE Rv1204c|M.tuberculosis_H37Rv LPRAITLATEVLSGPAADDMAVAWAASAAALSSARMGR---FGDVDRLAE MMAR_4234|M.marinum_M VPRAITLATEVLAEPSADDTAIAWAASAAALASARMGR---FADVPQLAQ MUL_0955|M.ulcerans_Agy99 VPRAITLATEVLAEPSADDTAIAWAASAAALASARMGR---FADVPQLAQ Mflv_4479|M.gilvum_PYR-GCK PAEAVTVAKGILAADDAQDLAVAWASAAATLSSARMGR---FAEVDGLAQ MAB_3907c|M.abscessus_ATCC_199 FDEGLARAHAVLSDPVAPKQAVEFAAFGVGLTLPVAGRGHEFEPIAQRCR MSMEG_4205|M.smegmatis_MC2_155 ITEGLAIAERVLDHPECPRQATDFAAFACGLAMPVAGRGEAFLPIASRCR MAV_0578|M.avium_104 CQLAAERARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQAL Mvan_0244|M.vanbaalenii_PYR-1 PQAAVELAGTALAGNAVQPLAAMFGIWALVIGHGDLGDVDHLREAAARGY TH_4413|M.thermoresistible__bu PDEVFRHAG-AVVVDELPGIIGAETAWALTLAAGEAGRTAEAVAAADTGY MLBr_01753|M.leprae_Br4923 VARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAAD : : * Mb1236c|M.bovis_AF2122/97 RASAAEHPG-LLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA------ Rv1204c|M.tuberculosis_H37Rv RASAAEHPG-LLRFTVGLAQITSLLLAGDVAPAQELAKRFTDFA------ MMAR_4234|M.marinum_M RASEAEHPG-LLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFAEL-QQP MUL_0955|M.ulcerans_Agy99 RASEAEHPG-LLRFTVGLAQITTLLMAGEVAQAQELAQRFTDFAEL-QQP Mflv_4479|M.gilvum_PYR-GCK RGLDAAHPG-LLRFTLGLGQTLALIMNADVASAEHLARHYLSFSEF-QQP MAB_3907c|M.abscessus_ATCC_199 DDKKRTTDG-LIAAMVRYCDVLALTYTGQLDLAEERVAEYTKFSSAGQFL MSMEG_4205|M.smegmatis_MC2_155 -AQRKTTDG-MIRIMVFYGEVLALAYTGQFDLARQRAEEYAEFSSAGQFA MAV_0578|M.avium_104 RRATTSFEASHMRFWFGAVYGRACRLTGRIDEFVSTARRLADSARDVPGL Mvan_0244|M.vanbaalenii_PYR-1 DLALSAPEASQLRFSLGLMEIVGLRLAGALESARSVAARLRGQSQDVD-V TH_4413|M.thermoresistible__bu RLTARFSDAAYTRFTLTDAHVTALILAGRIAAAVDTATVLDRQVGDLPGG MLBr_01753|M.leprae_Br4923 DLAQEIGDR-FVSLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDT . . Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M GRAIGEVLLAHVLIVKGEFGAAAAMLEPAAA----ELERTG-YSWGPLSL MUL_0955|M.ulcerans_Agy99 GRAIGEVLLAHVLIVKGEFGTAAAMVEPAAA----ELERTG-YSWGPLSL Mflv_4479|M.gilvum_PYR-GCK GRAIGEVLLGHTLLASGRFGDAVTLLRQAAA----ALTYTG-YSWGPLAL MAB_3907c|M.abscessus_ATCC_199 AWAIARIMAGVVATQRGLFREAIEAFEQALA----AQRADRPLPWQLPAR MSMEG_4205|M.smegmatis_MC2_155 GWAIAKIMAGAAAMHSGRFRDAISAIEQALA----ALNAEISLPWQLPGR MAV_0578|M.avium_104 AYANLALLLGNAELARGAAAEAARLVQEALA-GAQIHEVT--SGLRPASY Mvan_0244|M.vanbaalenii_PYR-1 SHAVTAMLTGLSELCCGDLISAQRWFRESLARAAKFPDLS--VSVCELSG TH_4413|M.thermoresistible__bu TALLARGVAGRAALAAGRLDDAVAWLRDVVSVLFSADTAGGFYGFGYRYQ MLBr_01753|M.leprae_Br4923 VTRTFGLYVQTRALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVF Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M MLLAT-AIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKATV MUL_0955|M.ulcerans_Agy99 MLLAT-AIAQQGNIAETAKALRRAETRHGTKSALFAPELSLARAWAKATV Mflv_4479|M.gilvum_PYR-GCK TGLAQ-ALGQQGRAADASAVLTRAEASHGMRSALYAPDLALARAWTLAAA MAB_3907c|M.abscessus_ATCC_199 LLLAR-AYAALGRAVDGERVLDEAREHSGPHVAIHMPQMMLAKAWLVAAR MSMEG_4205|M.smegmatis_MC2_155 LLLAR-AYAAVGEVIEAERVLDDAMEHSGAFMALHEPQRTLAKACVAAAK MAV_0578|M.avium_104 FALAE-AHGRLGHPAQANEAIAGARSCVPPDFLFMHTGLALATGWALAAG Mvan_0244|M.vanbaalenii_PYR-1 LWLTT-ALAMSGNRAAAQDVYDQTLKTFDGEIVLWQSEARLAQAWLHAAN TH_4413|M.thermoresistible__bu HPYAT-ALAVLGHTAAAATALATLDEREFPSWRYLDHERTIALAWLRAAQ MLBr_01753|M.leprae_Br4923 AALAMGDVAAAVEASEACRPHLGADHGLVAIHLELMAAVALARGDVIVAR Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M RDQAGALFDTR----EAARAAERGKQSAVALCVWHDAVRLGDTRALAPVT MUL_0955|M.ulcerans_Agy99 RDQAGALFDTR----EAARAAERGKQSAVALCVWHDAVRLGDTRALAPVT Mflv_4479|M.gilvum_PYR-GCK RDLRGAVASAR----DAVHAAVQSGQDAVALRALQDCARLGDTHGLATAV MAB_3907c|M.abscessus_ATCC_199 GSDRGAVDAAR----RAADAAHSAGQYALEAEALHHAARFGDRTVGRRIE MSMEG_4205|M.smegmatis_MC2_155 GAHRSAIDIAR----SAADLARSSEQHAVEAEALHHCARFGDRTVARRLQ MAV_0578|M.avium_104 GQLREAVATAQ----AAARLARDRGQPTHELACIQAAAQWGDAAGAVRAR Mvan_0244|M.vanbaalenii_PYR-1 GSTSLAVAFAI----DAARAARKHGRPAREVVCLQAATQFGSTSSADRLR TH_4413|M.thermoresistible__bu GAVSTSIQRLR----AEAESARTAGRFAVELLCLQTAVQFGDRTCGPRLH MLBr_01753|M.leprae_Br4923 RLADNSVSATTGWHQMAALTTRARIAMAQGEPELARADIHAALACGADIQ Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M RLAAEIDCKVGNIVVRHARALADNDAGALASVADELAAIGMHAAAADAAA MUL_0955|M.ulcerans_Agy99 RLAAEIDCKVGNIVVRHARALANNDAGALASVADELAAIGMHAAAADAAA Mflv_4479|M.gilvum_PYR-GCK RLSDRIGCVTGPLCVAHLRALAAGDGAALDAVSADLETAGLPAAAADAAA MAB_3907c|M.abscessus_ATCC_199 SLCTRVHGPLTGLYARHALAVAHSDITGLEAVSADFEAAGLLLSAADAAA MSMEG_4205|M.smegmatis_MC2_155 GLVDRVDGPLARLYAQHAAAVAAADPVALDAVSSAFEQAGLMLSAADAAA MAV_0578|M.avium_104 ALADALSLPLADAIACHAEALRAGNGEALLTVAAAYRAIGDAAAAADAAA Mvan_0244|M.vanbaalenii_PYR-1 ELSSAVRGPRADAAYAHARALRKADGHGLLAAVGRYEAFGDRVAAVDAAA TH_4413|M.thermoresistible__bu QLEDRVDGPRVAVAARFADALHTGDGSGLRSIADEFEDMGDMVAAADAAA MLBr_01753|M.leprae_Br4923 ASLGISDSMELLAELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAG Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M QAERAGGR------------------------------------------ MUL_0955|M.ulcerans_Agy99 QAERAGGR------------------------------------------ Mflv_4479|M.gilvum_PYR-GCK QATFAHQRRGDRAGEVASRSRASRLSQVCGAPATPALEQVLNPMP----- MAB_3907c|M.abscessus_ATCC_199 QAVALRMRAGDRGKGSDAAARVLRMADRCGGVVTPAILAAAKPLP----- MSMEG_4205|M.smegmatis_MC2_155 QAVLLHDKAGHRRQSTESAAHALQLAGRCGGAATPAIRAAARPLP----- MAV_0578|M.avium_104 QASAAFVEGQQHQRGRYAAALAGELAEECGGLCTPALR-TPAGLK----- Mvan_0244|M.vanbaalenii_PYR-1 QAAVVLDKRGQREASIAAAATARRLATESGADTVTFRS-MRCSAV----- TH_4413|M.thermoresistible__bu HAAIAHRRRGLRGSALACSAHAQGLAERCGGAHTPALRRAAEDLP----- MLBr_01753|M.leprae_Br4923 YESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGW Mb1236c|M.bovis_AF2122/97 -------------------------------------------------- Rv1204c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_4234|M.marinum_M -------------------------------------------------- MUL_0955|M.ulcerans_Agy99 -------------------------------------------------- Mflv_4479|M.gilvum_PYR-GCK --LTGREREVAVMVSQGLTNKAIAQRLSVSVRTVEGHVYRACMKFGVPDR MAB_3907c|M.abscessus_ATCC_199 --ISSREREIAVLIGEGLSDKDIATRLQLSVRTVEGHIYRARMKLDADDR MSMEG_4205|M.smegmatis_MC2_155 --VTAREREVAALVAQGLLNREIAERLTVSVRTVEGHIYRACIKLGVADR MAV_0578|M.avium_104 --LSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSR Mvan_0244|M.vanbaalenii_PYR-1 --LTRRQREVIALAASGLSNREIADRLVTSVRTVESHFLRACRNTGTNTR TH_4413|M.thermoresistible__bu --LTDREREIVLLLGAGLTNREIADTLTLSVRTVENHIYKSMLKTGTSSR MLBr_01753|M.leprae_Br4923 ESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSR Mb1236c|M.bovis_AF2122/97 --------------------------- Rv1204c|M.tuberculosis_H37Rv --------------------------- MMAR_4234|M.marinum_M --------------------------- MUL_0955|M.ulcerans_Agy99 --------------------------- Mflv_4479|M.gilvum_PYR-GCK AALASTVGGMHGREGTA---------- MAB_3907c|M.abscessus_ATCC_199 EEFAKIVGSDLKPPEAS---------- MSMEG_4205|M.smegmatis_MC2_155 DELARMIWTDLTPLEADPR-------- MAV_0578|M.avium_104 DELATIIRSRPAGRES----------- Mvan_0244|M.vanbaalenii_PYR-1 DELIAFLLGDDRAPS------------ TH_4413|M.thermoresistible__bu DELAALLPRSPRPSDPRRAPRSPRRID MLBr_01753|M.leprae_Br4923 VQLVQEAARHN----------------