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MSGVGGGYGLTAASAAAVDDFLESARRHPAGMLIEGDAGIGKTTMWNTVVQRAAEAGFVVLTARAGQAES GLAHAAVADLLSAVDPEIVDALPDMQRLAAGRVQLRDHAGGRPADERATAAALLSAVHAAGARAPVLIAI DDVQWLDASSRAVLAFAARRLKGAVGVVATERTGQQSQERAASWLQVGTGGLARVQVAPMSLGALHSMLS DRLGRRFSRPAIVRIAEASGGNPLYALELARVMDGDMLRPGVRLPSTLAEVVGLRVDKLDDDVRDVLLVA ASVTQPTVDLLAQTLAVRAEQVTALLESAEVEGVIAIEGNRVRFTHPLLASGIYDSAAPARRREFHRRLA DIQTQPELRARHLALAATVADDATLATLDAAADSARARGAPAAAAELVELAIRLGGDRVSRRIRAAEHHY VAGDMPRAAELLDQVTGDLRPGVLRAIALNLRAGVRIFEDDYAGAVVLLERACADAADNDEVRVSSLVAL AFAQGMVGAFEDQFASALRAVAVAERAGVPALTSQALTTWVYVRLQAGGGLDGPALRRAVELEGADGDTP IPFRASAMQGLALAVTGQLEDADRQLAEIAQRCLHRGAEHDLMAVTGYRTLIAIWRGRFDDAGRLAADLL ERARQVGGSMALAMSICAAAAAYRGEETQAREFARQALEQGAGHVPLTAWARATLAFLEVSLGEHHRAVE AAEPLMALYRPFSGTEVITGSFLPDAAEALIALGRHDDAEQMVGALERNGAALDRPWMLAVGNRCRALLL VAQGDLDGALGAVERAMAEHDRLPMPFERARTQLVMGEVLRRLRRRDAAEQIVREALRQFDGLGSPVWAD RARKILARVNGSGRSGSVVLTDSELRIAEHVASGMSNKEVADALYVSVKTVETNLTRVYRKLGIRSRAQL GTQLAQLREA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5653 | - | - | 100% (921) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_1863 | - | 0.0 | 48.48% (922) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5449 | - | 3e-60 | 30.73% (947) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2515c | - | 5e-16 | 26.63% (597) | LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 0.0 | 66.74% (899) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv2488c | - | 5e-16 | 26.63% (597) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 3e-14 | 27.01% (422) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 1e-62 | 29.67% (927) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 7e-61 | 28.48% (934) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 7e-22 | 24.27% (960) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_3290 | - | 6e-63 | 29.85% (918) | regulatory protein |
| M. thermoresistible (build 8) | TH_3931 | - | 1e-112 | 42.78% (582) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 8e-21 | 26.41% (602) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Mvan_5653|M.vanbaalenii_PYR-1 ----------------------------MMSGVGGGYGLTAASAAAVDDF
Mflv_1156|M.gilvum_PYR-GCK -------------------------------------------MKAVDDF
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 --------------------MVQVSGVSRDDGPVAGLIGRRDECAVLDQL
MMAR_0085|M.marinum_M -------------------------------MPTVTLVGRHREQQQLQQL
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------MIGGELLIGRDSELAAIR
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLDTTAIAKLDRTLTELVREHRGVCPV
Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLDTTAIAKLDRTLTELVREHRGVCPV
Mvan_5653|M.vanbaalenii_PYR-1 LESARR-HPAGMLIEGDAGIGKTTMWNTVVQRAAEAGFVVLTARAGQAES
Mflv_1156|M.gilvum_PYR-GCK LAGLQQLQPAGLLIEGEAGIGKTTMLAGVVDAARQAGFRVLSAHGDQSGS
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ------------MLRGQAGVGKTALLRYVLGKASGQ--LIAQASGIQSEM
MSMEG_3290|M.smegmatis_MC2_155 VDAVAGGASRALMIRGEAGVGKTALLDYAAARAAEL--QIARIVGIQSEM
MMAR_0085|M.marinum_M LDAARRGESGVLVLRGDAGIGKTTLLTDLVDNAPDL--RVLRVRGAEMEM
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 RALNGADHHRGVVIAGAAGVGKTWLARAALRRAGASGEQIKWIVGTQSAQ
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 EQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSPDEG
Rv2488c|M.tuberculosis_H37Rv EQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSPDEG
Mvan_5653|M.vanbaalenii_PYR-1 GLAHAAVADLLSAVDPEIVDALPDMQRLAAGRVQLRDHAGGRPADERATA
Mflv_1156|M.gilvum_PYR-GCK GLAHAAIADLFAGVQTDILDGLPELQRRAADGVLRRGDGTGGPTDERVIA
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ELAFAGLQQFCAPLTKYSG-AIPDPQREALTIAFGT--RSGPPPDRFLIG
MSMEG_3290|M.smegmatis_MC2_155 ELAFAGIHQLCLPLLPRLG-HLPVPQRDALEVALGM--ATGSSPDRFLVG
MMAR_0085|M.marinum_M ELTYSGVQQLCGPLMSLIG-QLPEPQLDALEIALGR--KRGRAPDRLLLG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ALPLGAFIGLLGDAMSEPLTSVRR--------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 NCVGPTIDRTARLR-ELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGTYR
Rv2488c|M.tuberculosis_H37Rv NCVGPTIDRTARLR-ELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGTYR
Mvan_5653|M.vanbaalenii_PYR-1 AALLSAVHAAGARAPVLIAIDDVQWLDASSRAVLAFAARRLKG-AVGVVA
Mflv_1156|M.gilvum_PYR-GCK AALLGAVHGSATRTPVLVAVDDVQWLDPSSVAVLAFVARRVKG-RVGFVV
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 LAVLSLLAAAAEHQPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLF
MSMEG_3290|M.smegmatis_MC2_155 LAVLNLLADAAADRPLLCLVDDEQWLDRSSAQVLAFVARRLGSESVGMIF
MMAR_0085|M.marinum_M LAVLTLVGEASRASPILCVVDDAQWVDSASVQALAFVARRIHVDPVAMVF
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --VIETFVARQRRGRVVVGVDDAHLLDGLSALVVHQLAQ-----SGGVRL
MLBr_02341|M.leprae_Br4923 --------------------MTTALVCVACGAELRSIAKFCDECGSPVVE
Mb2515c|M.bovis_AF2122/97 LDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVDEV
Rv2488c|M.tuberculosis_H37Rv LDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVDEV
Mvan_5653|M.vanbaalenii_PYR-1 TERTGQQSQERAASWLQVGTGGLARVQVAPMSLGALHSMLSDRLGRRFSR
Mflv_1156|M.gilvum_PYR-GCK AERPGVGPGLPAATWLQVGTGALTRLPVAPMSLGALHTMLSSRLGRRFSR
TH_3931|M.thermoresistible__bu --------------------------------------VLLARLGRTFPR
MAB_3361|M.abscessus_ATCC_1997 AVRDGTDSELAGLPELTVHG----------LRAADAGTLLDSVIPGLLDE
MSMEG_3290|M.smegmatis_MC2_155 AAREPSD-AAAGVPALVVRG----------LRGADARALLDSALSAPLDP
MMAR_0085|M.marinum_M ATRDRGPDALTGHCELSLQG----------LEDHDARLVLSTAIPGRLND
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 VVTVRTGSHQPDAVTALWKDDLLTRLDLEPLSAAATREVIESTLGGPVDA
MLBr_02341|M.leprae_Br4923 AETPAEYKQVTVLFADVVGS-----------------MDIAAAVGLERLR
Mb2515c|M.bovis_AF2122/97 AQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGY----PDGVWYVN
Rv2488c|M.tuberculosis_H37Rv AQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGY----PDGVWYVN
Mvan_5653|M.vanbaalenii_PYR-1 PAIVRIAEAS----------GGNPLYALELARVMDGDM----LRPGVRLP
Mflv_1156|M.gilvum_PYR-GCK PQIVRIAEVS----------GGNPLYALELARVADGAG----SRPGQRLP
TH_3931|M.thermoresistible__bu AVMVQIHHIS----------GGNPFYALELARAMDDG------SPLVRLP
MAB_3361|M.abscessus_ATCC_1997 RVRDRIVAET----------QGNPLALLELPRDMTAEE----LAGGFGWP
MSMEG_3290|M.smegmatis_MC2_155 RVRDQILAET----------DGNPLALLELPRTLTRDA----LAGVFGLP
MMAR_0085|M.marinum_M SVAETVLAEA----------NGNPLALLELHNALIRGE----LAGGYGLA
MUL_2555|M.ulcerans_Agy99 ----------------------MPALSANLVASIDRHP----ERITLRCD
MAV_0578|M.avium_104 RCAARFRRLT----------GGNTLFLRQLLSDQMAAGRMRRVAGVWMWD
MLBr_02341|M.leprae_Br4923 EIMTELVSRA----------AGVIERYGGTVDKFTGDG----IMAIFGAP
Mb2515c|M.bovis_AF2122/97 LAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEH
Rv2488c|M.tuberculosis_H37Rv LAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEH
Mvan_5653|M.vanbaalenii_PYR-1 ------STLAEVVGLRVDKLDDDVRDVLLVAASVTQPTVDLLAQTLAVRA
Mflv_1156|M.gilvum_PYR-GCK ------ESLSELVRLRVDGLAEDVRDVLLVAASATSPTVDLLAKAVGVTP
TH_3931|M.thermoresistible__bu ------SSLTELVRARIGRIGADARNVLLAAACSAAPTVESVARAVGVDE
MAB_3361|M.abscessus_ATCC_1997 DGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTLLARAAQQLG
MSMEG_3290|M.smegmatis_MC2_155 GGSGVAADIEHAFGVRIGELPEPTRDLLLIAAAEPTGDAPLVWRAAARLG
MMAR_0085|M.marinum_M NATRTETQIERTFVSRLRALPSETKTFLLVAAAESTARPEWLWAAAHRLG
MUL_2555|M.ulcerans_Agy99 DLQSVFAELGAGPGDRVAALPGDRTRRRVCGPACELSGGRFRPSARPQSC
MAV_0578|M.avium_104 GDVAVSASLSDTVGRQLGRLTPPLALVVDTLSQCEPLPVDLLCDLASRED
MLBr_02341|M.leprae_Br4923 -----TALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSG
: :
Mb2515c|M.bovis_AF2122/97 LLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHGEAIEL
Rv2488c|M.tuberculosis_H37Rv LLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHGEAIEL
Mvan_5653|M.vanbaalenii_PYR-1 EQVTALLESAEVEGVIAIEGNRVRFTHPLLAS--GIYDSAAPARRREFHR
Mflv_1156|M.gilvum_PYR-GCK AAVTGLVEAAEVEGIVVIDGNRIRFTHPVLAN--GIYAGADPQRRREVHR
TH_3931|M.thermoresistible__bu PRVVRLLSDAVDRDIIRMDGHRICFSHPLLAR--GVYDDATATRRRAMHR
MAB_3361|M.abscessus_ATCC_1997 -IPMHAIAPAEAADLVELST-RVRFRHPLVRS--AVYISANPLERRRIHG
MSMEG_3290|M.smegmatis_MC2_155 -IGSDAAAPAVEAELASFDT-RVTFQHPLVRS--VVYRAAALDDRRRAHR
MMAR_0085|M.marinum_M -IGPEAAAPAEAAGLIAAQG-SVRFRHPLIRA--AVYHSSSAAERRRVHA
MUL_2555|M.ulcerans_Agy99 PGLTEAASPGRSRGPLHLARCAAELT----------IRRGDACQAIELLR
MAV_0578|M.avium_104 LVAAEAMGLVTVER--TPRALMARLAHPLFGE--LRRAGAGEMYLSTIRG
MLBr_02341|M.leprae_Br4923 QVIVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTA
Mb2515c|M.bovis_AF2122/97 FTDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTE
Rv2488c|M.tuberculosis_H37Rv FTDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTE
Mvan_5653|M.vanbaalenii_PYR-1 RLADIQT---QPELRARHLALAATVAD--DATLATLDAAADSARARGAPA
Mflv_1156|M.gilvum_PYR-GCK RLADLKT---DPELRARHLALASTVAD--ETTLTTLDAAADAARARGAPA
TH_3931|M.thermoresistible__bu RLAEIVD---EPELQARHLAIAVGWAD--PQVLACLDRAAEAARLRGAPS
MAB_3361|M.abscessus_ATCC_1997 VLAGATDPGADPDRRAWHRAHAAAGTD--EAIAWELEQSAGRAQAKGGVL
MSMEG_3290|M.smegmatis_MC2_155 ALAAATDAEVDPDRRAWHLAHAAAGPD--AAAAAELESSAARARSRGGAC
MMAR_0085|M.marinum_M ALAASIAGPDDDDHRVWHRAHAAEAPD--AQTADDLERSAERARARGGLS
MUL_2555|M.ulcerans_Agy99 RAGELSD----RPRRREQLLASAAFVALQAAQLDEAERLLADAGLGGGAS
MAV_0578|M.avium_104 RLATRLAQDQDADMQATVRRALLTLESDLDPQPELYLESARHAMTLLDLD
MLBr_02341|M.leprae_Br4923 VLGAPQTVRIKGAEDAVPARRLLRVAE---PRQPTWFSESTLVGREWELA
.
Mb2515c|M.bovis_AF2122/97 IVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAV
Rv2488c|M.tuberculosis_H37Rv IVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAV
Mvan_5653|M.vanbaalenii_PYR-1 AAAELVELAIRLGGD---RVSRR---------------------------
Mflv_1156|M.gilvum_PYR-GCK AAAELLEWAMQLGGD---SVSRR---------------------------
TH_3931|M.thermoresistible__bu TAAELIDMAIGLGGD---SPERR---------------------------
MAB_3361|M.abscessus_ATCC_1997 AAAAFLQRATELTADPAARGRRA---------------------------
MSMEG_3290|M.smegmatis_MC2_155 AAAAFLERATALTVDPVLRNDRA---------------------------
MMAR_0085|M.marinum_M AAASFLEHATKLTPDPFVRASRA---------------------------
MUL_2555|M.ulcerans_Agy99 ASALLISSFISLYRYGDVTATHR---------------------------
MAV_0578|M.avium_104 LADRLANAAARAGAPGAAGVRAMN--------------------------
MLBr_02341|M.leprae_Br4923 TLAAMLDRSIGGRGSVVGLVGPAG--------------------------
: .
Mb2515c|M.bovis_AF2122/97 FPSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRL
Rv2488c|M.tuberculosis_H37Rv FPSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRL
Mvan_5653|M.vanbaalenii_PYR-1 ------IRAAEHHYVAGDMP------------------------------
Mflv_1156|M.gilvum_PYR-GCK ------IRAAEHHVVAGDMR------------------------------
TH_3931|M.thermoresistible__bu ------LMSARNHVDAGDGD------------------------------
MAB_3361|M.abscessus_ATCC_1997 ------LAAAQSKYDAAAFD------------------------------
MSMEG_3290|M.smegmatis_MC2_155 ------LAAAAAKAEAGAFE------------------------------
MMAR_0085|M.marinum_M ------LDAAMTSLEAGMPD------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ----------LVLLGRGEQ-------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 LETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQ
Rv2488c|M.tuberculosis_H37Rv LETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQ
Mvan_5653|M.vanbaalenii_PYR-1 -------RAAELLDQVTGDLRPGVLRAIALNLRAGVRIFEDDY-------
Mflv_1156|M.gilvum_PYR-GCK -------RAATLLEQALVDLRPGVLCAIALNLLAGVRMVEDDY-------
TH_3931|M.thermoresistible__bu -------SARAILKRSSAEMT-GAPRAQVLRLLGGLEILYGSY-------
MAB_3361|M.abscessus_ATCC_1997 -------AARELLGVADMTPLDPLARARATRLRAKIAFAESRVGAFGSVT
MSMEG_3290|M.smegmatis_MC2_155 -------SAQDLLAMVEATSLSDLQQAQVDVLRARLAFVTSHG-------
MMAR_0085|M.marinum_M -------SATRLVASAAAAADDELIAARCELIRAKIAFAASRG-------
MUL_2555|M.ulcerans_Agy99 ---------RLVERLQSADDLDGETLTRMVNLLLAVSMFAADP-------
MAV_0578|M.avium_104 -------AEEALRAITDGADGDASDRHYWATVRAANLVWMLGR-------
MLBr_02341|M.leprae_Br4923 -------IGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFD-------
.
Mb2515c|M.bovis_AF2122/97 AELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAA
Rv2488c|M.tuberculosis_H37Rv AELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAA
Mvan_5653|M.vanbaalenii_PYR-1 -AGAVVLLERACADAADNDEVRVSSLVALAFAQGMVGAFEDQFAS-----
Mflv_1156|M.gilvum_PYR-GCK -IRAVELLERARAD-ADNDAVLVTTLLSLGFCLGMTGSFTAQLAT-----
TH_3931|M.thermoresistible__bu -LDAADALRRALTDATDDAVLRARILTLLAFVEFNTGRRAAAAAD-----
MAB_3361|M.abscessus_ATCC_1997 VSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRGG--AVE
MSMEG_3290|M.smegmatis_MC2_155 -SDAPPLLLKAARRLGGIDPDRARAVYLDAMLAAMFAGRLATGAN--LVE
MMAR_0085|M.marinum_M -SDAPPLLLAAAQRMQRLDPSESRKAYLGAVLASILVGRMATDQHNSSPS
MUL_2555|M.ulcerans_Agy99 ---ALWQITDGLVDSLADRLGELSVIYRDAWADAARRG------------
MAV_0578|M.avium_104 -PADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAER-----
MLBr_02341|M.leprae_Br4923 ---VVAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLG---
: .
Mb2515c|M.bovis_AF2122/97 ALADHDAHPAGADPGLYARALADRALIDAVAGITDRLDDAQKALAIARDI
Rv2488c|M.tuberculosis_H37Rv ALADHDAHPAGADPGLYARALADRALIDAVAGITDRLDDAQKALAIARDI
Mvan_5653|M.vanbaalenii_PYR-1 ALRAVAVAERAGVPALTSQALTTWVYVRLQAGGGLDGPALRRAVELEGAD
Mflv_1156|M.gilvum_PYR-GCK VREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLRAVDLEDPE
TH_3931|M.thermoresistible__bu ADEAVECATRAGDRGVLSQALAMRTLVTCLLGRGFDPAALHRALELEEPG
MAB_3361|M.abscessus_ATCC_1997 VAEPARLAPAGAQPARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCE
MSMEG_3290|M.smegmatis_MC2_155 VAAAARSAPERSGAAEVSDLLLDWLTAHYGRGYVAARSALGDVLSAFDGE
MMAR_0085|M.marinum_M VAKAASNAPAAPHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRE
MUL_2555|M.ulcerans_Agy99 ----RTVTQRLKEQLDRLAELEPWDVMRVALAG-----------------
MAV_0578|M.avium_104 -----ARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRR
MLBr_02341|M.leprae_Br4923 -----IADPAVELPRLDPDARRRRLTALINVAQLALSRPAVFVVED----
.
Mb2515c|M.bovis_AF2122/97 EDPALLARALTACGG--------VAAYNADLARPWLAEAVGLARAVGDKW
Rv2488c|M.tuberculosis_H37Rv EDPALLARALTACGG--------VAAYNADLARPWLAEAVGLARAVGDKW
Mvan_5653|M.vanbaalenii_PYR-1 GDTPIPFRASAMQGL------ALAVTGQLEDADRQLAEIAQRCLHRGAEH
Mflv_1156|M.gilvum_PYR-GCK DNTPIPFRASAARGL------SLALTGRLAEADGQLAAVAQRSAQRGAEQ
TH_3931|M.thermoresistible__bu SGDLGITRTSGLHAM------LLAYTGRFDAAVEVMRAVARHCRDRGEGL
MAB_3361|M.abscessus_ATCC_1997 AD-RPANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVGALS
MSMEG_3290|M.smegmatis_MC2_155 AD-DLP-LNRMLLAS-----TAAHYAWDDVRLDVFTAHHVERARATGALS
MMAR_0085|M.marinum_M RDIGVAEPGWHDLTA-----RVCLDLFDQDAYNFLAARQVEDLRAAGALT
MUL_2555|M.ulcerans_Agy99 -----------------------YYVDLIDDFRSVLVPLADREIEGGAAT
MAV_0578|M.avium_104 ATTSFEASHMRFWFG--------AVYGRACRLTGRIDEFVSTARRLADSA
MLBr_02341|M.leprae_Br4923 ------------------------VHWIDEVSDSMLADFLAVIPQTRSMA
Mb2515c|M.bovis_AF2122/97 RLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWAL
Rv2488c|M.tuberculosis_H37Rv RLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWAL
Mvan_5653|M.vanbaalenii_PYR-1 DLMAVTGYRTLIAIWR-GRFDDAGRLAADLLERARQVGGSMA--LAMSIC
Mflv_1156|M.gilvum_PYR-GCK DVMAVLGYRTLVAIWR-GRYAEADAYAADTMERAEQLGGSMV--IAFSIC
TH_3931|M.thermoresistible__bu DLTYIALHRVLVELWR-GEVRAAATIAEEAIESAAVLDGDLPRGVVLLLR
MAB_3361|M.abscessus_ATCC_1997 LLPAALIYRAGMHVHA-GELDAAAELVQEADAISAATGHAPI----RYHS
MSMEG_3290|M.smegmatis_MC2_155 EVPIALNSRAIALLFF-GDLDGAADAVDEIQAADDATGALLA----PYAE
MMAR_0085|M.marinum_M MLPVALVTFAGVCVSA-GNFGQADALLDESAAIIAATGAPPR----PAIK
MUL_2555|M.ulcerans_Agy99 IALATLALVAAYQLAS-GQWAEAVDTSQRGVALCSQHHYELFGYQLRGYL
MAV_0578|M.avium_104 RDVPGLAYANLALLLGNAELARGAAAEAARLVQEALAGAQIH--------
MLBr_02341|M.leprae_Br4923 LVTYRPEYHGALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQIGE
.
Mb2515c|M.bovis_AF2122/97 AAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDT
Rv2488c|M.tuberculosis_H37Rv AAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDT
Mvan_5653|M.vanbaalenii_PYR-1 AAAAAYRGEETQAR--EFARQALEQGAGHVPLTAWARATLAFLEVSLGEH
Mflv_1156|M.gilvum_PYR-GCK AAVAAYRGREDQAR--DQAAGALAQGGDYVALTVWASATLAFLEVSRGNY
TH_3931|M.thermoresistible__bu QALATYAGRVDDARGDGARAAAIFARSGSAILTTLTTSLTGFLELSVGDH
MAB_3361|M.abscessus_ATCC_1997 LILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLGRY
MSMEG_3290|M.smegmatis_MC2_155 VGLAAMRGDLARTASLVDATVAAVTARGEGNGLTVAWWAEAVLHNGFGSA
MMAR_0085|M.marinum_M TYLAAYRGQEQICREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQY
MUL_2555|M.ulcerans_Agy99 GVISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFAEGDY
MAV_0578|M.avium_104 EVTSGLRPASYFALAEAHGRLGHPAQANEAIAGARSCVPPDFLFMHTGLA
MLBr_02341|M.leprae_Br4923 LITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATLQA
Mb2515c|M.bovis_AF2122/97 EAAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATR
Rv2488c|M.tuberculosis_H37Rv EAAAAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATR
Mvan_5653|M.vanbaalenii_PYR-1 HRAVEAAEPLMALYR-PFSGTEVITGSFLPDAAEALIALGRHDDAEQMVG
Mflv_1156|M.gilvum_PYR-GCK EQALEAAEPLVDLYR-DFPGTELMSACFMPDAIESLIAVGRLDEAEPLIA
TH_3931|M.thermoresistible__bu VAAIATLRPLLPILGPDLEGTEIITAGFLPDLVEAQVLMGLLDDAEPLVQ
MAB_3361|M.abscessus_ATCC_1997 ELAFMAAR-----RACEH-EDLGLYSWCLIELIEAAVRCGEHDTAVKAFG
MSMEG_3290|M.smegmatis_MC2_155 RKALEAAS-----RAAAFPPELASANWALIELVEAATRCGAVETAAEAAA
MMAR_0085|M.marinum_M QEAFNAAA-----SGARY-DDVGMCGYLLGELIEAAVRCKEHNAATEALG
MUL_2555|M.ulcerans_Agy99 ESAYLQATAIT--APGEFPPLALHATRTLFDLVEAAVHTDRLNEARRHVR
MAV_0578|M.avium_104 LATGWALA------------AGGQLREAVATAQAAARLARDRGQPTHELA
MLBr_02341|M.leprae_Br4923 TIAARIDR------------LSPPAKQLLVAAAVIGFRFGSDLLASLGID
: :
Mb2515c|M.bovis_AF2122/97 FFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRG---VHRAR
Rv2488c|M.tuberculosis_H37Rv FFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRG---VHRAR
Mvan_5653|M.vanbaalenii_PYR-1 ALERNGAALDRPWMLAVGNRCRALLLVAQGDLDGALGAVERAMAEHDRLP
Mflv_1156|M.gilvum_PYR-GCK AFERNGAELDRPWQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHARLP
TH_3931|M.thermoresistible__bu ALTRNGRRLDRPWMLAVAARCRAMMLAARGDLAGAVAAVX---XXGRRRS
MAB_3361|M.abscessus_ATCC_1997 QLEERALAAQSDWSQGMVARSRALITVGHDAEPHYREAIQR----LTNTR
MSMEG_3290|M.smegmatis_MC2_155 DLAELTTSSGTDWALGLAARARALVSGPAESERWYLESIER----LENTR
MMAR_0085|M.marinum_M RLLKRTKASGTPTALGIGASATALVSDGSIADAAYREAITH----LRRSP
MUL_2555|M.ulcerans_Agy99 AAKRLQFADAPPRLAIATGAAEALCASDERAPALFEKVLGHP----AVAS
MAV_0578|M.avium_104 CIQAAAQWGDAAGAVRARALADALSLPLADAIACHAEALRAG-----NGE
MLBr_02341|M.leprae_Br4923 LSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKSDRARLHRRL
Mb2515c|M.bovis_AF2122/97 ALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMA
Rv2488c|M.tuberculosis_H37Rv ALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMA
Mvan_5653|M.vanbaalenii_PYR-1 MPFERARTQLVMGEVLRRLRRRDAAEQIVREALRQFDGLGSPVWADRARK
Mflv_1156|M.gilvum_PYR-GCK MPFERARSALTLGEVLRRLRRRDAAA-AVRDALAQFEELGVPLWVARARI
TH_3931|M.thermoresistible__bu GPGAAAR----HRGAVRRRRRPDRRG-------------------ARAGR
MAB_3361|M.abscessus_ATCC_1997 ISAHLARAHLIYGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAERAER
MSMEG_3290|M.smegmatis_MC2_155 ARAELARSRLVYGEWLRRERRRTAARSELRTAHEMFSAMGMSAFAARAQR
MMAR_0085|M.marinum_M VAVHLARTHLTYGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAERARR
MUL_2555|M.ulcerans_Agy99 FPFEHARIRLAYGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRARN
MAV_0578|M.avium_104 ALLTVAAAYRAIGDAAAAADAAAQASAAFVEGQQHQRGRYAAALAGELAE
MLBr_02341|M.leprae_Br4923 AAAIEARAPHSVDQHAVLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRA
.
Mb2515c|M.bovis_AF2122/97 DAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEF
Rv2488c|M.tuberculosis_H37Rv DAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEF
Mvan_5653|M.vanbaalenii_PYR-1 ILARVNGSGRS---------------------------------------
Mflv_1156|M.gilvum_PYR-GCK ALSGLAVSGSA---------------------------------------
TH_3931|M.thermoresistible__bu PAGGTQPVGLL---------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ELRATGAKVRK---------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 ELAAAGDRIRET--------------------------------------
MMAR_0085|M.marinum_M ELSATGEAVYV---------------------------------------
MUL_2555|M.ulcerans_Agy99 ELRAAGTAVRHS--------------------------------------
MAV_0578|M.avium_104 ECGGLCTPALR---------------------------------------
MLBr_02341|M.leprae_Br4923 ARVSWEHATKI---------------------------------------
Mb2515c|M.bovis_AF2122/97 DDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEG
Rv2488c|M.tuberculosis_H37Rv DDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEG
Mvan_5653|M.vanbaalenii_PYR-1 -------------------------------GSVVLTDSELRIAEHVASG
Mflv_1156|M.gilvum_PYR-GCK -------------------------------VGSELTDSERRIAELAASG
TH_3931|M.thermoresistible__bu -------------------------------VRTVPRRT-ARHGRIPAPG
MAB_3361|M.abscessus_ATCC_1997 ---------------------------RSASSEKALTAQEAQIARMAGQG
MSMEG_3290|M.smegmatis_MC2_155 ---------------------------VIAAVDHRLTAQEAHIARLARDG
MMAR_0085|M.marinum_M ---------------------------QPTGITVDLTTQESHIARLARDG
MUL_2555|M.ulcerans_Agy99 ----------------------------AAVGPAPLTAQERLVAELAAKG
MAV_0578|M.avium_104 -----------------------------TPAGLKLSGRQRDVIELAVAG
MLBr_02341|M.leprae_Br4923 -------------------------------ADALTAEDPHRAAMCIAPR
Mb2515c|M.bovis_AF2122/97 LSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGP
Rv2488c|M.tuberculosis_H37Rv LSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGP
Mvan_5653|M.vanbaalenii_PYR-1 MSNKEVADALYVSVKTVETNLTRVYRKLGIRSRAQLGTQLAQLREA----
Mflv_1156|M.gilvum_PYR-GCK MSNRDVAETLFVSVKTIETNLSRVYRKLGIRSRAQLGRMLR---------
TH_3931|M.thermoresistible__bu RXRGDRADRAPGSQRGGRAGPADRTRGAVADAAGR---------------
MAB_3361|M.abscessus_ATCC_1997 LTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLR------SGR----
MSMEG_3290|M.smegmatis_MC2_155 LSNPEIGARLFISARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR----
MMAR_0085|M.marinum_M YTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRELRAILMESP------
MUL_2555|M.ulcerans_Agy99 LSNKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI
MAV_0578|M.avium_104 LSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDELATIIRSRPAGRES-
MLBr_02341|M.leprae_Br4923 TRLCGIAWRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDR
. .
Mb2515c|M.bovis_AF2122/97 SRP
Rv2488c|M.tuberculosis_H37Rv SRP
Mvan_5653|M.vanbaalenii_PYR-1 ---
Mflv_1156|M.gilvum_PYR-GCK ---
TH_3931|M.thermoresistible__bu ---
MAB_3361|M.abscessus_ATCC_1997 ---
MSMEG_3290|M.smegmatis_MC2_155 ---
MMAR_0085|M.marinum_M ---
MUL_2555|M.ulcerans_Agy99 ---
MAV_0578|M.avium_104 ---
MLBr_02341|M.leprae_Br4923 LH-