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ARPRAFDEAAVVEASRDLFWDQGYAATSIDDLSAATGLGRGSFYKAFGDKHSMFVRGLELYCTEAVDGIR AELRNPDLSAYDRLVAHIRGAADSVASDTDRRGCLLAKSAAELSSTDPVVARHVKRTLDAWLRELTATIS AAQADGDIPSETDAKSMASLLLAVLRGMEALRKGGASAATIKSAAEQAIALLGVQPGTPPTPSMA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5917 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5842 | - | 5e-20 | 31.41% (191) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1617 | - | 5e-15 | 26.32% (190) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | 2e-09 | 25.39% (193) | hypothetical protein Mb2184c |
| M. gilvum PYR-GCK | Mflv_0944 | - | 2e-88 | 82.90% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 1e-05 | 25.31% (162) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_00815 | - | 2e-05 | 24.00% (125) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1881c | - | 1e-09 | 25.41% (185) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0630 | - | 5e-50 | 46.31% (203) | transcriptional regulatory protein |
| M. avium 104 | MAV_1733 | - | 7e-08 | 29.63% (162) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5597 | - | 2e-20 | 31.09% (193) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1150 | - | 1e-06 | 28.12% (160) | TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR |
| M. ulcerans Agy99 | MUL_4864 | - | 9e-07 | 30.27% (185) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5917|M.vanbaalenii_PYR-1 -------------------------------MARPRAFD-EAAVVEASRD
Mflv_0944|M.gilvum_PYR-GCK -------------------------------MARPRTFD-EDEVIEAGRD
MMAR_0630|M.marinum_M -------------------------------MARPRAFD-EAVVLSAARD
Rv3855|M.tuberculosis_H37Rv ---------------MTTSAASQASLPRGRRTARPSGDDRELAILATAEN
TH_1150|M.thermoresistible__bu ---------------MSTASPVRS---RGRRSTRPSGDDRELAILTTAEK
MSMEG_5597|M.smegmatis_MC2_155 -------------------------------MGRHREFD-VDKALDAALC
MAV_1733|M.avium_104 -----------------MPSVTRTPPGRRSPGREQRREQLERRLLDATER
MAB_1881c|M.abscessus_ATCC_199 --------------MLSGMVGKSSPPSAAKLPATAHGRRTRAAIIDAAAQ
MUL_4864|M.ulcerans_Agy99 ---------------MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVA
Mb2184c|M.bovis_AF2122/97 ------------------------------MPSADVGRQTRAQILRAAMD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
. .
Mvan_5917|M.vanbaalenii_PYR-1 LFWD-QGYAATSIDDLSAATGLGRGSFYKAFGDKHSMFVRGLELYCTEAV
Mflv_0944|M.gilvum_PYR-GCK LFWS-QGYAATSIDDLSAATGLGRGSLYKAFGDKHSMFLRGLEQYCTEAI
MMAR_0630|M.marinum_M EFRS-HGYAATSVDSLAAATGLNRSSLYGSFGDKHRLFLRALDGYCEATL
Rv3855|M.tuberculosis_H37Rv LLED-RPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQAD
TH_1150|M.thermoresistible__bu LLAE-RPLAEISVDDLAKGAGLSRPTFYFYFPSKDAVLLALVERVIAEAD
MSMEG_5597|M.smegmatis_MC2_155 VFWR-KGYEGASYSDLTQATGVERPALYSAFGNKEALFLRALDRYYERYM
MAV_1733|M.avium_104 LMRDGASFTELSVDRLAGAAGISRASFYIYFEDKGHLLRRLASRVFGELT
MAB_1881c|M.abscessus_ATCC_199 MMYQ-KGVAATSLDDILAASSTGKSQLYHYFKDRSELVKAVVERQTELVL
MUL_4864|M.ulcerans_Agy99 EIGR-RGLAGADVAAIAAAAGVARGTFYFHFPTKEHVLVELER----AEE
Mb2184c|M.bovis_AF2122/97 IASV-KGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFE
MLBr_00815|M.leprae_Br4923 VFVD-HGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLV
. : . : :: * : :
Mvan_5917|M.vanbaalenii_PYR-1 DGIRAELRNPDLSAYDRLVAHIRGAADSVASDTDRRGCLLAKSAAELSST
Mflv_0944|M.gilvum_PYR-GCK AGIRAELRDQDLSAYDRLVAHVRGRAADVVSDNDLRGCLLAKSAAELSST
MMAR_0630|M.marinum_M HDVREVLRERGVSARQRLINHVHAIVNGIVADTDRRGCMMSRSSAELAGA
Rv3855|M.tuberculosis_H37Rv MALQTLAE--NPADTD--RENMWRTGINVFFETFGSHKAVTRAGQAARAT
TH_1150|M.thermoresistible__bu QRADAALNGMDARAVD--PAGVWR-AINALFETFGAHRAVTLAGAAARTT
MSMEG_5597|M.smegmatis_MC2_155 DFIPVALEQPTSREVA--EHLLRSAADLNTRYPDHTGCLGVQGCLVGTDD
MAV_1733|M.avium_104 DGARRWWSVAGRHDPD-----DVRAAMTRIIATYRRHQAVLVALNEMSGY
MAB_1881c|M.abscessus_ATCC_199 AAQPTLTQIDSMDGVE---QWAQAILANHDVPGGPFGCPLGSMAAELKN-
MUL_4864|M.ulcerans_Agy99 LAIVAKLRDPTADSTD--LVSVLSSLAHQVVAVERRLGPLVFRDMLGLHF
Mb2184c|M.bovis_AF2122/97 AEVVAPAMAAPPGVDR-VRALMHAWVGYLERDVFPGGCFFAAAAADVDSQ
MLBr_00815|M.leprae_Br4923 SSVQQALRTTTNNRQR-----LHAAVQAFFDFIEHDGQGYRLIFENDNIT
Mvan_5917|M.vanbaalenii_PYR-1 DPVVARHVKRTLDAWLRELTATISAAQADGDIPSETDAKSMASLLLAVLR
Mflv_0944|M.gilvum_PYR-GCK DPEVARHVKRTLDAWLRELTATISAAQADGDIPSSTEAKALAALILAVLR
MMAR_0630|M.marinum_M DPDVSGIVERSLEAWRRELADCIAEAQLEGAVAGDGSPQALATVMLSLMQ
Rv3855|M.tuberculosis_H37Rv SVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNE
TH_1150|M.thermoresistible__bu NTEVDALWSRFMKKWIDYTAESIRAERERGAAPDTIPAEDLAVSLNLMNE
MSMEG_5597|M.smegmatis_MC2_155 SEPIRRALVDARASGEASLRARFEDAHATGDLPKSANPAALAAFLMTVLH
MAV_1733|M.avium_104 DPLTAQTYREILTGISGQLTRVIEDGQADGSIRPRLAAATTASALTWMVE
MAB_1881c|M.abscessus_ATCC_199 DPAYQPALAAAFGQWQSLLADGLIRMQDRGHLDPHEDPQRLAAAVLATLQ
MUL_4864|M.ulcerans_Agy99 APTRPVEDQLGEHPLAEFVIETIAQAQRADRVAPDADAGELGVIFLTGLF
Mb2184c|M.bovis_AF2122/97 PGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAM
MLBr_00815|M.leprae_Br4923 EPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCAR
. . .
Mvan_5917|M.vanbaalenii_PYR-1 GM---EALRKGGASAATIKSAAEQAIALLGVQPGTPPTPSMA--
Mflv_0944|M.gilvum_PYR-GCK GM---EALRKGGASAATVKATAEQLVAML---------------
MMAR_0630|M.marinum_M GF---EALGKGGVGSAELRAAESAALALL-FGAGTDPKP-----
Rv3855|M.tuberculosis_H37Rv RT---LFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR-----
TH_1150|M.thermoresistible__bu RT---MFAAFADEKPAVPEDRIVDTLAHIWLTSIYGTGR-----
MSMEG_5597|M.smegmatis_MC2_155 GM---AVQAKAGFSRETLDAIIDQALSSWPTPDRGSAGKATRKR
MAV_1733|M.avium_104 RA---CQQNLP-AQPSAYDAELADTLAEIVWGALYLKPASGS--
MAB_1881c|M.abscessus_ATCC_199 GG---MLMGRATMDITVLRDSLEMALDSIRRALRD---------
MUL_4864|M.ulcerans_Agy99 -----ALLATGATTPDARTALLNGFVTTVVHGMEAR--------
Mb2184c|M.bovis_AF2122/97 EANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES------
MLBr_00815|M.leprae_Br4923 YW---LDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-------