For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LSGMVGKSSPPSAAKLPATAHGRRTRAAIIDAAAQMMYQKGVAATSLDDILAASSTGKSQLYHYFKDRSE LVKAVVERQTELVLAAQPTLTQIDSMDGVEQWAQAILANHDVPGGPFGCPLGSMAAELKNDPAYQPALAA AFGQWQSLLADGLIRMQDRGHLDPHEDPQRLAAAVLATLQGGMLMGRATMDITVLRDSLEMALDSIRRAL RD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1881c | - | - | 100% (213) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3312 | - | 3e-30 | 35.75% (207) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1494 | - | 1e-10 | 27.55% (196) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0202 | - | 5e-10 | 26.60% (203) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0944 | - | 3e-09 | 27.33% (161) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0196 | - | 6e-10 | 26.60% (203) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0630 | - | 2e-09 | 26.63% (184) | transcriptional regulatory protein |
| M. avium 104 | MAV_0149 | - | 2e-12 | 29.69% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5206 | - | 2e-26 | 35.75% (193) | regulatory protein |
| M. thermoresistible (build 8) | TH_3160 | - | 2e-08 | 25.14% (179) | PUTATIVE putative regulatory protein, TetR |
| M. ulcerans Agy99 | MUL_2793 | - | 4e-09 | 26.95% (167) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4594 | - | 1e-25 | 35.42% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5206|M.smegmatis_MC2_155 -----------MDQQVQKLTPKGAATRRRIIEGAAAEIHSRGVADTTLDD
Mvan_4594|M.vanbaalenii_PYR-1 -----------MDSQVHKLTVKGRATRDRIVEGAAAEIRERGVAATTLDD
MAB_1881c|M.abscessus_ATCC_199 MLSGMVGKSSPPSAAKLPATAHGRRTRAAIIDAAAQMMYQKGVAATSLDD
Mb0202|M.bovis_AF2122/97 ----------------------MQGPRERMVVSAALLIRERGAHATAISD
Rv0196|M.tuberculosis_H37Rv ----------------------MQGPRERMVVSAALLIRERGAHATAISD
TH_3160|M.thermoresistible__bu -----------MGVEVTRRRDPQSGPRAAMLRSAVALMRRQGVAATSFAD
MUL_2793|M.ulcerans_Agy99 -----------------------MTARERLIESAIELLRRNGVAGTGLAD
MAV_0149|M.avium_104 ---------------------MATATRERFLTAATGLFRRQGYSGTGLKQ
Mflv_0944|M.gilvum_PYR-GCK ------------------MARPRTFDEDEVIEAGRDLFWSQGYAATSIDD
MMAR_0630|M.marinum_M ------------------MARPRAFDEAVVLSAARDEFRSHGYAATSVDS
. .: .. : .* * . .
MSMEG_5206|M.smegmatis_MC2_155 IRARTGTSKSQLFHYFPGGKDQLMLAVAEHEAQQVLADQQPYLGDLTS-W
Mvan_4594|M.vanbaalenii_PYR-1 IRARTQTSKSQLFHYFPDGKDQLLLAVAEHEAHMVLEDQQPHLGELTS-W
MAB_1881c|M.abscessus_ATCC_199 ILAASSTGKSQLYHYFKD-RSELVKAVVERQTELVLAAQ-PTLTQIDS-M
Mb0202|M.bovis_AF2122/97 VLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEGGL
Rv0196|M.tuberculosis_H37Rv VLQHSGAPRGSAYHYFPGGRTQLLCEAVDYAG----EHVAAMINEAEGGL
TH_3160|M.thermoresistible__bu VLADSGAPRGSIYHHFPAGKAQLIEEATRTAAAQLTERVARVLDEAADLP
MUL_2793|M.ulcerans_Agy99 LLEHSGTARRSVYVNFPGGKSELMTEATRTAG---RLMDSTLASIAAGGG
MAV_0149|M.avium_104 IVAESRAPLGSLYHFFPGGKQDLAVQAIAHTAERYRELLDRVFAKSTDIG
Mflv_0944|M.gilvum_PYR-GCK LSAATGLGRGSLYKAFGDKHSMFLRGLEQYCTEAIAGIRAELRDQDLSAY
MMAR_0630|M.marinum_M LAAATGLNRSSLYGSFGDKHRLFLRALDGYCEATLHDVREVLRERGVSAR
: : . : * : : .
MSMEG_5206|M.smegmatis_MC2_155 TSWQRWRDAVVDRYRRQGQ--HCPLSTLMSELGR-----STPGAQAVSRA
Mvan_4594|M.vanbaalenii_PYR-1 AAWRRWRDAVVDRYRRQGQ--HCPLAVLMSEIGR-----TTPGAEAVSAA
MAB_1881c|M.abscessus_ATCC_199 DGVEQWAQAILANHDVPGGPFGCPLGSMAAELK------NDPAYQPALAA
Mb0202|M.bovis_AF2122/97 ELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAA
Rv0196|M.tuberculosis_H37Rv ELLDALIDKYRQQLLSTDFRAGCPIAAVSVEAGDEQDRERMAPVIARAAA
TH_3160|M.thermoresistible__bu TALRELVGVWRDGLEAGDYAVGCPIVAAALGT------ERAARDVA--GV
MUL_2793|M.ulcerans_Agy99 QPLVAFADSWKQTLRASDYAAGCPIVAAALGRTE----SPSAADVA--GE
MAV_0149|M.avium_104 QATVTWFNWAARALQETDYADGCPIGTVACEVAS-----SNEALRQATQA
Mflv_0944|M.gilvum_PYR-GCK DRLVAHVRGRAADVVSDNDLRGCLLAKSAAELSS-----TDPEVARHVKR
MMAR_0630|M.marinum_M QRLINHVHAIVNGIVADTDRRGCMMSRSSAELAG-----ADPDVSGIVER
* :
MSMEG_5206|M.smegmatis_MC2_155 LLRQWHDEITTGIRHMQGHGEITADLDAERMAAALLAGIQGGVNVMLVTG
Mvan_4594|M.vanbaalenii_PYR-1 LVTKWHGEIATGIRDMQAQGKIADRVDADRTAAALLAGIQGGVGIMLSTG
MAB_1881c|M.abscessus_ATCC_199 AFGQWQSLLADGLIRMQDRGHLDPHEDPQRLAAAVLATLQGGMLMGRATM
Mb0202|M.bovis_AF2122/97 VFDRWSDLTAQRFIADG-----IPPDRAHELAVLATSTLEGAILLARVRR
Rv0196|M.tuberculosis_H37Rv VFDRWSDLTAQRFIADG-----IPPDRAHELAVLATSTLEGAILLARVRR
TH_3160|M.thermoresistible__bu AFADLTGLISDKLVSDG-----MARRRANSVAVLILTAMEGALVLAQARR
MUL_2793|M.ulcerans_Agy99 VFGAWQTVLAGRFRAQG-----VGDDTAESLATTVVAAVEGAVILCLAAR
MAV_0149|M.avium_104 VLASWQSRVAAELIGAG-----VPTAQARRLATFAVASLEGAILLARAHR
Mflv_0944|M.gilvum_PYR-GCK TLDAWLRELTATISAAQADGDIPSSTEAKALAALILAVLRGMEALRKGGA
MMAR_0630|M.marinum_M SLEAWRRELADCIAEAQLEGAVAGDGSPQALATVMLSLMQGFEALGKGGV
. : : . *. : :.* :
MSMEG_5206|M.smegmatis_MC2_155 DLTYLEAALDSGIAALQRG------
Mvan_4594|M.vanbaalenii_PYR-1 DLGFLEAALDVGIAALRD-------
MAB_1881c|M.abscessus_ATCC_199 DITVLRDSLEMALDSIRRALRD---
Mb0202|M.bovis_AF2122/97 DLTPLDLVHRQLRNLLLAELPERSR
Rv0196|M.tuberculosis_H37Rv DLTPLDLVHRQLRNLLLAELPERSR
TH_3160|M.thermoresistible__bu DPAALDAVVDELT-LLCSGSAD---
MUL_2793|M.ulcerans_Agy99 STDPLDRTVPMLQQLIAQHTSRPSG
MAV_0149|M.avium_104 STRPLRETGRVVADTLRAATDRG--
Mflv_0944|M.gilvum_PYR-GCK SAATVKATAEQLVAML---------
MMAR_0630|M.marinum_M GSAELRAAESAALALLFGAGTDPKP
. : :