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MARPRAFDEAVVLSAARDEFRSHGYAATSVDSLAAATGLNRSSLYGSFGDKHRLFLRALDGYCEATLHDV REVLRERGVSARQRLINHVHAIVNGIVADTDRRGCMMSRSSAELAGADPDVSGIVERSLEAWRRELADCI AEAQLEGAVAGDGSPQALATVMLSLMQGFEALGKGGVGSAELRAAESAALALLFGAGTDPKP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0630 | - | - | 100% (202) | transcriptional regulatory protein |
| M. marinum M | MMAR_4335 | - | 9e-06 | 26.88% (160) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1268 | - | 1e-05 | 28.69% (122) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 3e-05 | 27.95% (161) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0944 | - | 5e-48 | 47.15% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 3e-05 | 27.95% (161) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-06 | 32.95% (88) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1881c | - | 1e-09 | 26.63% (184) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1140 | - | 6e-08 | 25.95% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1509 | - | 9e-16 | 28.36% (201) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3775 | - | 2e-10 | 28.34% (187) | PUTATIVE TetR-family protein transcriptional regulator |
| M. ulcerans Agy99 | MUL_2620 | - | 1e-05 | 28.69% (122) | hypothetical protein MUL_2620 |
| M. vanbaalenii PYR-1 | Mvan_5917 | - | 4e-50 | 46.31% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0944|M.gilvum_PYR-GCK ---------------------------MAR-----PRTFDEDEVIEAGRD
Mvan_5917|M.vanbaalenii_PYR-1 ---------------------------MAR-----PRAFDEAAVVEASRD
MMAR_0630|M.marinum_M ---------------------------MAR-----PRAFDEAVVLSAARD
Mb0244|M.bovis_AF2122/97 ---------------------------MAGGTKRLPRAVREQQMLDAAVQ
Rv0238|M.tuberculosis_H37Rv ---------------------------MAGGTKRLPRAVREQQMLDAAVQ
MSMEG_1509|M.smegmatis_MC2_155 ---------------------------MAR-----HKEFDPDVALDTAMR
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_3775|M.thermoresistible__bu ----------------------------------MAETDDKNRVLATATT
MAB_1881c|M.abscessus_ATCC_199 --------------MLSGMVGKSSPPSAAKLPATAHGRRTRAAIIDAAAQ
MAV_1140|M.avium_104 ---------------------------MTTHSTDGRADATRQQILRAASH
MUL_2620|M.ulcerans_Agy99 -----------------MERKRQRNTTRVREAGAASRAQTRHLLLTAAAE
: ..
Mflv_0944|M.gilvum_PYR-GCK LFWSQGYAATSIDDLSAATGLGRGSLYKAFGDKHSMFLRGLE----QYCT
Mvan_5917|M.vanbaalenii_PYR-1 LFWDQGYAATSIDDLSAATGLGRGSFYKAFGDKHSMFVRGLE----LYCT
MMAR_0630|M.marinum_M EFRSHGYAATSVDSLAAATGLNRSSLYGSFGDKHRLFLRALD----GYCE
Mb0244|M.bovis_AF2122/97 MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN----REMS
Rv0238|M.tuberculosis_H37Rv MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLN----REMS
MSMEG_1509|M.smegmatis_MC2_155 VFWRSGYAHTSTEDLVTELGIARASLYGTYGSKRGLYLAALD----RYLT
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLE----RHMN
TH_3775|M.thermoresistible__bu LFNERGVQAVGMDAIRDAAGISLKRLYSCFRSKADLVAAVLE----QRDA
MAB_1881c|M.abscessus_ATCC_199 MMYQKGVAATSLDDILAASSTGKSQLYHYFKDRSELVKAVVE----RQTE
MAV_1140|M.avium_104 QFARRPYHDVGLDDILAEAELTKGAMYFHFKSKHALAVAIIE----SQTA
MUL_2620|M.ulcerans_Agy99 EFARVGYVASTVSRIAEGAGVTVQTLYLAWGSKRALLRGYLESTLAPDAA
: . : :* : .: : ::
Mflv_0944|M.gilvum_PYR-GCK EAIAGIRAELRDQDLSAYDRLVAHVRGRAADVVSDNDLRGCLLAKSAAEL
Mvan_5917|M.vanbaalenii_PYR-1 EAVDGIRAELRNPDLSAYDRLVAHIRGAADSVASDTDRRGCLLAKSAAEL
MMAR_0630|M.marinum_M ATLHDVREVLRERGVSARQRLINHVHAIVNGIVADTDRRGCMMSRSSAEL
Mb0244|M.bovis_AF2122/97 RFIDALRSSIN-FDQSPKDLLRNTIVSFLRYIDAN---------RASWIV
Rv0238|M.tuberculosis_H37Rv RFIDALRSSIN-FDQSPKDLLRNTIVSFLRYIDAN---------RASWIV
MSMEG_1509|M.smegmatis_MC2_155 GGGD--PAQLVASAASGLDAVRALLESAARQPDQGLP-PGCFSVNATVEH
MLBr_00815|M.leprae_Br4923 NLVSSVQQALR-TTTNNRQRLHAAVQAFFDFIEHD--------GQGYRLI
TH_3775|M.thermoresistible__bu DVRRAMTEYVQSRAADPRDRILAVFDFLAHWFAES-DFRGCMFINTIGEL
MAB_1881c|M.abscessus_ATCC_199 LVLAAQPTLTQIDSMDGVEQWAQAILANHDVPGGP---FGCPLGSMAAEL
MAV_1140|M.avium_104 SGAVAVQDLLTRGLSGLETLIDFSYLIAVKDIKTD-------LVRSGLNL
MUL_2620|M.ulcerans_Agy99 PSGQHFAAQLQPDSPAGTLAQVSALVCDAARRSAIAWRAYRDGSGVDSAI
Mflv_0944|M.gilvum_PYR-GCK SSTDPEVARHVKRTLDAWLRELTATISAAQADGDIPS----STEAKALAA
Mvan_5917|M.vanbaalenii_PYR-1 SSTDPVVARHVKRTLDAWLRELTATISAAQADGDIPS----ETDAKSMAS
MMAR_0630|M.marinum_M AGADPDVSGIVERSLEAWRRELADCIAEAQLEGAVAG----DGSPQALAT
Mb0244|M.bovis_AF2122/97 MYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGP----LTDAEIEMM
Rv0238|M.tuberculosis_H37Rv MYTQATSSQAFAHTVREGREQIVQLVAELVRAGTRGP----LTDAEIEMM
MSMEG_1509|M.smegmatis_MC2_155 GDTDPEIGARLERNRERMETVFRDALLRARAEGDLDTRLCDDSEISSTAT
MLBr_00815|M.leprae_Br4923 FENDNITEPRVAAQVRVATESCIDAVFALISADSRLD----PHRARMVAV
TH_3775|M.thermoresistible__bu GGTSTDVRRIARLHKTAVRDYLADLVAAAELP----------SELAEQLA
MAB_1881c|M.abscessus_ATCC_199 K-NDPAYQPALAAAFGQWQSLLADGLIRMQDRGHLDP----HEDPQRLAA
MAV_1140|M.avium_104 MESVGLSDGLQEKLFDRWIKALARVAEQAKGEGDINE----HCDPQDIGR
MUL_2620|M.ulcerans_Agy99 AAEWHQIQMLRRETMRALLVTIPDDALRLPRQDAVDTAWAITSPASQPAS
Mflv_0944|M.gilvum_PYR-GCK LILAVLRGMEALR--KGGAS-AATVKATAEQLVAML--------------
Mvan_5917|M.vanbaalenii_PYR-1 LLLAVLRGMEALR--KGGAS-AATIKSAAEQAIALLGVQPGTPPTPSMA-
MMAR_0630|M.marinum_M VMLSLMQGFEALG--KGGVG-SAELRAAESAALALL-FGAGTDPKP----
Mb0244|M.bovis_AF2122/97 AVALVGAGEAVAT--RLGIG-DTDVDEAAEMMINLFWLGLKGAPVDRLET
Rv0238|M.tuberculosis_H37Rv AVALVGAGEAVAT--RLGIG-DTDVDEAAEMMINLFWLGLKGAPVDRLET
MSMEG_1509|M.smegmatis_MC2_155 LLTTVLNGLQVLS--RAGADQRGRIARTVESALAGLRAR-----------
MLBr_00815|M.leprae_Br4923 GLVGISVDCARYW--LDTNR-PISKSDAVEGTVQFAWGGLSHVPLTRL--
TH_3775|M.thermoresistible__bu ILADGAIVAATIW--GDGTDAAAAARRAAATLISAS--------------
MAB_1881c|M.abscessus_ATCC_199 AVLATLQGGMLMG--RATMD-ITVLRDSLEMALDSIRRALRD--------
MAV_1140|M.avium_104 LMVSLHMGLRKTSNLDDPERFLRDLEKCWSLLLTGILQPDRTEYFQQFLR
MUL_2620|M.ulcerans_Agy99 QPATRSWLPTAGSPCSALKPGSPPPCKTPSCAIRRAAGEPRRAAPPRRLV
:
Mflv_0944|M.gilvum_PYR-GCK -----------------
Mvan_5917|M.vanbaalenii_PYR-1 -----------------
MMAR_0630|M.marinum_M -----------------
Mb0244|M.bovis_AF2122/97 GH---------------
Rv0238|M.tuberculosis_H37Rv GH---------------
MSMEG_1509|M.smegmatis_MC2_155 -----------------
MLBr_00815|M.leprae_Br4923 -----------------
TH_3775|M.thermoresistible__bu -----------------
MAB_1881c|M.abscessus_ATCC_199 -----------------
MAV_1140|M.avium_104 RRAALAINTSATDDDES
MUL_2620|M.ulcerans_Agy99 NRAEQRPILMSHLTA--