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AVGRPREFDPESVEQEAMQLFWERGFDGVSISDITAATGVNRRSIYAEFGSKEKLFERATLRYLAGPGGY LTEALTQPTARAVAEAMVHGAADTVSGDPHGCLTVGNAPGLSELRESTVQRIAERFDAAVADGELPAVDT MVLARWIAAVCQGLAVQARSGAGRAELHAVADLALAGWPKPPHPAVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5842 | - | - | 100% (188) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1617 | - | 1e-41 | 46.63% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5917 | - | 4e-20 | 31.41% (191) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0710c | - | 7e-06 | 37.04% (54) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0944 | - | 1e-18 | 33.68% (193) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0691c | - | 7e-06 | 37.04% (54) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0835c | - | 2e-08 | 46.05% (76) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0630 | - | 5e-13 | 29.38% (194) | transcriptional regulatory protein |
| M. avium 104 | MAV_4481 | - | 9e-07 | 38.89% (54) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2030 | - | 2e-31 | 40.31% (191) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2855 | - | 3e-06 | 25.31% (162) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1500 | - | 4e-07 | 35.80% (81) | transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0710c|M.bovis_AF2122/97 ----------------------------MPHESRVGRRRSTTPHHISDVA
Rv0691c|M.tuberculosis_H37Rv ----------------------------MPHESRVGRRRSTTPHHISDVA
MAV_4481|M.avium_104 ----------------------------MPQQ-RVGRRRSTTPHHITDVA
Mvan_5842|M.vanbaalenii_PYR-1 --------------------------------MAVGRPREFDPESVEQEA
MSMEG_2030|M.smegmatis_MC2_155 ------------------------------MATVRGRPRSFDRDAALDKA
Mflv_0944|M.gilvum_PYR-GCK ----------------------------------MARPRTFDEDEVIEAG
MMAR_0630|M.marinum_M ----------------------------------MARPRAFDEAVVLSAA
TH_2855|M.thermoresistible__bu LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPR-IRPEEIVSAA
MUL_1500|M.ulcerans_Agy99 --------------------------------MHLATDDRTARARIRDEA
MAB_0835c|M.abscessus_ATCC_199 --------------------------MTDTSAETTILTEDSTDQRLLNAA
. .
Mb0710c|M.bovis_AF2122/97 IELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQL
Rv0691c|M.tuberculosis_H37Rv IELFAAHGFTDVSVDDIARAAGIARRTLFRYYASKNAIPWGDFSTHLAQL
MAV_4481|M.avium_104 IDLFTARGFAEVSVDDVAAAAGISRRTLFRYYASKNAIPWGDFDTHLARL
Mvan_5842|M.vanbaalenii_PYR-1 MQLFWERGFDGVSISDITAATGVNRRSIYAEFGSKEKLFERATLRYLAGP
MSMEG_2030|M.smegmatis_MC2_155 IRLFWERGFEATSTRDLSSALGIGMPSIYAAFGDKRQLFAEAVEVYDARY
Mflv_0944|M.gilvum_PYR-GCK RDLFWSQGYAATSIDDLSAATGLGRGSLYKAFGDKHSMFLRGLEQYCTEA
MMAR_0630|M.marinum_M RDEFRSHGYAATSVDSLAAATGLNRSSLYGSFGDKHRLFLRALDGYCEAT
TH_2855|M.thermoresistible__bu AEFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICLTVTKEP
MUL_1500|M.ulcerans_Agy99 LRLFAERGPDAVTMRDIATAAGVSPALLIRHYGSKDGLIEAVDNHVIAIF
MAB_0835c|M.abscessus_ATCC_199 ERLFAERGVDAVSLRAIMAAAGTNVASVHYHFGSKERLIEALLDRYLDQI
* .* . : * * : :..* :
Mb0710c|M.bovis_AF2122/97 Q------GLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQ
Rv0691c|M.tuberculosis_H37Rv Q------GLLDNIDSRIQLRDALRAALLAFNTFDESETIRHRKRMRVILQ
MAV_4481|M.avium_104 R------ELLDNVESRVPLGDALRTALLAFNTFDESETARHRQRMRVILQ
Mvan_5842|M.vanbaalenii_PYR-1 G------GYLTEALTQ--PTARAVAEAMVHGAAD--TVSGDPHGCLTVGN
MSMEG_2030|M.smegmatis_MC2_155 G------GFIDAALDQE-PTARAAVARILAQAPGRYTRRGLPSGCLIISG
Mflv_0944|M.gilvum_PYR-GCK I------AGIRAELRDQDLSAYDRLVAHVRGRAADVVSDNDLRGCLLAKS
MMAR_0630|M.marinum_M L------HDVREVLRERGVSARQRLINHVHAIVNGIVADTDRRGCMMSRS
TH_2855|M.thermoresistible__bu -------NELNLPLLDAAGTPAERLSALIRAHLEHLIRRR----VEHLVA
MUL_1500|M.ulcerans_Agy99 E------VLLTEATRETEAVGLG--QAAVGGLLDGLATHLPPDSAVPAYL
MAB_0835c|M.abscessus_ATCC_199 EKRRFALLDVAETARTLRAIAEAIVTPLSEIAEEGSTAWLSTLGKLLISG
:
Mb0710c|M.bovis_AF2122/97 TPELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQ--TVAWTMLGVAL
Rv0691c|M.tuberculosis_H37Rv TPELQAYSMTMYAGWREVIAKFVARRSGGKTTDFMPQ--TVAWTMLGVAL
MAV_4481|M.avium_104 TAELQAYSMTMYAGWREVIAGFVARRCECKTTDLAPQ--TVAWMMLGVAL
Mvan_5842|M.vanbaalenii_PYR-1 APG-----------LSELRESTVQRIAERFDAAVADG--ELPA-VDTMVL
MSMEG_2030|M.smegmatis_MC2_155 DDGSA--DETVGAALRRIREKKTQTVADKIRADIAAG--ELPADTDALAL
Mflv_0944|M.gilvum_PYR-GCK AAELSSTDPEVARHVKRTLDAWLRELTATISAAQADG--DIPSSTEAKAL
MMAR_0630|M.marinum_M SAELAGADPDVSGIVERSLEAWRRELADCIAEAQLEG--AVAGDGSPQAL
TH_2855|M.thermoresistible__bu LHDINSLTPEHRAIIDDLRRYYQRRVRDVIVAGVRSGEFDVPDPKLAALL
MUL_1500|M.ulcerans_Agy99 SRMLISGGTAGPGLFARLFRLSQDTLNAMAAAGTASPGADPAVRAAFLLV
MAB_0835c|M.abscessus_ATCC_199 HPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFG-VTHAVTLTCVVL
. :
Mb0710c|M.bovis_AF2122/97 SAYEHWLRDE--SVSLTEALGAAFDVVGAGLDRLNQ----------
Rv0691c|M.tuberculosis_H37Rv SAYEHWLRDE--SVSLTEALGAAFDVVGAGLDRLNQ----------
MAV_4481|M.avium_104 SAYEHWLGDE--SVPLPVALGNAFDVVGAGLNGLDR----------
Mvan_5842|M.vanbaalenii_PYR-1 ARWIAAVCQG--LAVQARSGAGRAELHAVADLALAGWPKPPHPAVV
MSMEG_2030|M.smegmatis_MC2_155 AQFVMSTLSG--IAQAARDGIPRARLDQVAAIALRAWPQR------
Mflv_0944|M.gilvum_PYR-GCK AALILAVLRG--MEALRKGGASAATVKATAEQLVAML---------
MMAR_0630|M.marinum_M ATVMLSLMQG--FEALGKGGVGSAELRAAESAALALLFGAGTDPKP
TH_2855|M.thermoresistible__bu ILDALNGVSG--WFHPDRGHSLPDVIAAYTEMIVERVLRARIS---
MUL_1500|M.ulcerans_Agy99 NDLAVLTLRPRLIEVLGVDPLTDAGMRRWAGEVFAVYRDGLVSD--
MAB_0835c|M.abscessus_ATCC_199 GDIAHTNRLMSLSGTYLDDGQMNAQLIDMVTAILAGPPDES-----
: .