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MPSADVGRQTRAQILRAAMDIASVKGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEA EVVAPAMAAPPGVDRVRALMHAWVGYLERDVFPGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITAD VETAQRRGEIRADIEARQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | - | 100% (206) | hypothetical protein Mb2184c |
| M. bovis AF2122 / 97 | Mb3233 | - | 1e-05 | 27.17% (92) | TetR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb0149 | - | 1e-05 | 26.09% (161) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2447 | - | 1e-08 | 28.24% (170) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2160c | - | 7e-53 | 99.03% (103) | hypothetical protein Rv2160c |
| M. leprae Br4923 | MLBr_00815 | - | 4e-07 | 26.17% (149) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3199c | - | 5e-09 | 31.08% (148) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4739 | - | 3e-08 | 25.43% (173) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5134 | - | 2e-07 | 33.33% (93) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 5e-07 | 29.41% (153) | TetR-type regulator |
| M. thermoresistible (build 8) | TH_0256 | - | 3e-09 | 25.57% (176) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4780 | - | 7e-07 | 28.07% (171) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5917 | - | 3e-09 | 25.39% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2447|M.gilvum_PYR-GCK ------------MSAPESVGSDLETSRRPYAALFAKGEDRRQRILAVAER
TH_0256|M.thermoresistible__bu -----------------------VTQTRPYETLLAKGEDRRQRILAVAER
MMAR_4739|M.marinum_M -----------------------MPEVRPYDTLLAKGEDRKQRILGVAQR
Mb2184c|M.bovis_AF2122/97 ------------------------------MPSADVGRQTRAQILRAAMD
Rv2160c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3199c|M.abscessus_ATCC_199 --------------------------MTRAGTKGMPRAERERQILDAACQ
MSMEG_3807|M.smegmatis_MC2_155 -------------------------MTSSVKPARADATRNREALLAAAEE
MUL_4780|M.ulcerans_Agy99 ---------------------------MVADFGRPRDPRIDGAVLRATVE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAV_5134|M.avium_104 -----------------------MSHPVRATAIADTDTSTRQRILAATAE
Mvan_5917|M.vanbaalenii_PYR-1 --------------------------------MARPRAFDEAAVVEASRD
Mflv_2447|M.gilvum_PYR-GCK LLARNGWRNTSLAQIAREAGVTPAGLLHHFESKEQLLNAVLDARD-----
TH_0256|M.thermoresistible__bu LLARNGWRNTSLAQIAKEAGVSPAGLLHHFESKEALLNAVLDARD-----
MMAR_4739|M.marinum_M LLSRNGWRNTTLAQIAGEAGVTPAGLLHHFESKEQLLHAVLDARD-----
Mb2184c|M.bovis_AF2122/97 IASVKGLSGLSIGELAGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEA
Rv2160c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3199c|M.abscessus_ATCC_199 EFGRSGYVGMSLAAVAAAVGVSKPMVLAYFGSKEQLYIACVERAGATVG-
MSMEG_3807|M.smegmatis_MC2_155 EFAERGLA-ASVADIARRAGVAKGTVFRHFPTKEDLIAAIVTAHT-----
MUL_4780|M.ulcerans_Agy99 LLAETGYAGLLVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPID-----
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNN---
MAV_5134|M.avium_104 VLGRNGKTKLSLSDVATQAGVSRPTLYRWFASKEELLSAFSAYER-----
Mvan_5917|M.vanbaalenii_PYR-1 LFWDQGYAATSIDDLSAATGLGRGSFYKAFGDKHSMFVRGLELYCTEAVD
Mflv_2447|M.gilvum_PYR-GCK ----ADDDAHADRGGDLVTELARVPERFERSPELVGTFMVLLAENIAP-D
TH_0256|M.thermoresistible__bu ----ADDDAHADRSGDLIAEIARVAERFDRAPHLVGTFTVLLVENIQP-E
MMAR_4739|M.marinum_M ----LDDDAHADRLGDLIGEIAQVADRFTRAPELVGTFTVLLAENIDP-D
Mb2184c|M.bovis_AF2122/97 -EVVAPAMAAPPGVDRVRALMHAWVGYLERDVFPGGCFFAAAAADVDSQP
Rv2160c|M.tuberculosis_H37Rv -------MGRIPGTRRA-----------------GGCFFAAAAADVDSQP
MAB_3199c|M.abscessus_ATCC_199 ---DHIEAAMTAAPPTLALPRAVLQAIFQALAPRPSDWLVIWDQTLPEGS
MSMEG_3807|M.smegmatis_MC2_155 ----ATLSETARSLVDAPDPGAALLEFLTEAADQRRQHDLTFLQAASADD
MUL_4780|M.ulcerans_Agy99 --AATAVPDTGSPVDDLREMVRRTTAVLSTPAAKAAQPGLIGEMAADP--
MLBr_00815|M.leprae_Br4923 -LVSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEN-----D
MAV_5134|M.avium_104 ----QIFESGLVKATAGLKGVDKLDAVLRFIVDYQHSYSGVRMVDVEP--
Mvan_5917|M.vanbaalenii_PYR-1 GIRAELRNPDLSAYDRLVAHIRGAADSVASDTDRRGCLLAKSAAELSSTD
Mflv_2447|M.gilvum_PYR-GCK APLHDRLHKRYRDAVDIIEDIITRGQRKGLYRTDFDAASKATEILAFING
TH_0256|M.thermoresistible__bu APLHDRMLARQRAAIDIVADLIRRGQESGRYRSDFDAATKAVEIIAFVNG
MMAR_4739|M.marinum_M APLHDRLVSRQRDACEIVAEAIRRGQEAGRYRADLDPTVKAVEILAFIHG
Mb2184c|M.bovis_AF2122/97 GPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAME
Rv2160c|M.tuberculosis_H37Rv GPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELHAYAME
MAB_3199c|M.abscessus_ATCC_199 EALAAARVARTRLAALAGQGVAAVGSAATQLRDAQDIGVLTQGWMGMVGA
MSMEG_3807|M.smegmatis_MC2_155 SSVTAARDELHG----YVEQLVAAAREAGAIRADVTGTDVFLLMCTPIHV
MUL_4780|M.ulcerans_Agy99 TLHSALLVRFGEIFGHGLTTWLDNAAARGQVRADVTAPELAEAIAGIVLI
MLBr_00815|M.leprae_Br4923 NITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVD
MAV_5134|M.avium_104 ----EHTIAQFSWVIPQMREGLQR-HLPGPNAAVKAATVIRIAISHYIVR
Mvan_5917|M.vanbaalenii_PYR-1 PVVARHVKRTLDAWLRELTATISAAQADGDIPSETDAKSMASLLLAVLRG
Mflv_2447|M.gilvum_PYR-GCK --METLWLLDP---SIPLTEVFKGYAESLGRDLAL---------------
TH_0256|M.thermoresistible__bu --METSWLLDP---SIPVAEVFKGYAEMLERDFAPPNPT-----------
MMAR_4739|M.marinum_M --MEMTWLLDP---SIPLTEVFKEYAEALARDFSLPSTT-----------
Mb2184c|M.bovis_AF2122/97 --ANWALLLLD---DDGAGERARTAIDAALARVGTTQEGVES--------
Rv2160c|M.tuberculosis_H37Rv --ANWALLLLD---DDGAGERARTAIDAALARVGTTQEGVES--------
MAB_3199c|M.abscessus_ATCC_199 --MITWWIRHP---EQSAEQMAERASRLIGIIASAGISEAEAPEGGAVPR
MSMEG_3807|M.smegmatis_MC2_155 --VENLPDPSPDLWQRYLGILFDGLRPEGAHPLPQPPPRLT---------
MUL_4780|M.ulcerans_Agy99 GLLTRPGELEP----GVGDAWIDRTTTLLLKGIRKGTPQ-----------
MLBr_00815|M.leprae_Br4923 --CARYWLDTN--RPISKSDAVEGTVQFAWGGLSHVPLTRL---------
MAV_5134|M.avium_104 --------------SDDADQFLAQLRHAVGIKAPTD--------------
Mvan_5917|M.vanbaalenii_PYR-1 --MEALRKGGAS--AATIKSAAEQAIALLGVQPGTPPTPSMA--------
Mflv_2447|M.gilvum_PYR-GCK --------------------------------------------------
TH_0256|M.thermoresistible__bu --------------------------------------------------
MMAR_4739|M.marinum_M --------------------------------------------------
Mb2184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2160c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3199c|M.abscessus_ATCC_199 PGTPVRGSGSGQPLNAAFDLFGRRWAILVVWELRSGTKTLPELKAEMGDA
MSMEG_3807|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4780|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
MAV_5134|M.avium_104 --------------------------------------------------
Mvan_5917|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2447|M.gilvum_PYR-GCK --------------------------------------------------
TH_0256|M.thermoresistible__bu --------------------------------------------------
MMAR_4739|M.marinum_M --------------------------------------------------
Mb2184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2160c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3199c|M.abscessus_ATCC_199 SSSVLATRLKELTAAHIVRNQDGQYSLTTVGKGLLVALAPLHLWAKAWSA
MSMEG_3807|M.smegmatis_MC2_155 --------------------------------------------------
MUL_4780|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00815|M.leprae_Br4923 --------------------------------------------------
MAV_5134|M.avium_104 --------------------------------------------------
Mvan_5917|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2447|M.gilvum_PYR-GCK ---
TH_0256|M.thermoresistible__bu ---
MMAR_4739|M.marinum_M ---
Mb2184c|M.bovis_AF2122/97 ---
Rv2160c|M.tuberculosis_H37Rv ---
MAB_3199c|M.abscessus_ATCC_199 SVR
MSMEG_3807|M.smegmatis_MC2_155 ---
MUL_4780|M.ulcerans_Agy99 ---
MLBr_00815|M.leprae_Br4923 ---
MAV_5134|M.avium_104 ---
Mvan_5917|M.vanbaalenii_PYR-1 ---