For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_1733 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 1709855 - 1710505
length: 216

PSVTRTPPGRRSPGREQRREQLERRLLDATERLMRDGASFTELSVDRLAGAAGISRASFYIYFEDKGHLL
RRLASRVFGELTDGARRWWSVAGRHDPDDVRAAMTRIIATYRRHQAVLVALNEMSGYDPLTAQTYREILT
GISGQLTRVIEDGQADGSIRPRLAAATTASALTWMVERACQQNLPAQPSAYDAELADTLAEIVWGALYLK
PASGS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1733--100% (216)transcriptional regulator, TetR family protein
M. avium 104MAV_5064-2e-1229.19% (185) transcriptional regulator, TetR family protein, putative
M. avium 104MAV_3926-2e-0925.57% (176) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3885ethR6e-1029.47% (207) transcriptional regulatory repressor protein (TETR-family)
M. gilvum PYR-GCKMflv_2639-1e-7565.12% (215) TetR family transcriptional regulator
M. tuberculosis H37RvRv3855ethR6e-1029.47% (207) transcriptional regulatory repressor protein (TETR-family)
M. leprae Br4923MLBr_00064-1e-1127.36% (212) putative transcriptional regulator
M. abscessus ATCC 19977MAB_0984c-3e-1328.50% (207) TetR family transcriptional regulator
M. marinum MMMAR_3762-9e-8672.90% (214) AcrR family transcriptional regulator
M. smegmatis MC2 155MSMEG_4622-1e-8673.36% (214) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_2600-7e-1329.59% (196) PUTATIVE putative transcriptional regulator, TetR family
M. ulcerans Agy99MUL_3708-2e-8572.43% (214) AcrR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_5684-3e-1329.58% (213) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1733|M.avium_104                MPSVTRTPPG-----------RRSPGREQRREQLERRLLDATERLMRDGA
MSMEG_4622|M.smegmatis_MC2_155      MPSVTRKP---------------QANREERRERIERALLDATDRLMSDGT
MMAR_3762|M.marinum_M               MASITRNA---------------QANRRQRREQMECRLLEATERLMNNGA
MUL_3708|M.ulcerans_Agy99           MASITRNA---------------QANRRQRREQMECRLLEATERLMNNGA
Mflv_2639|M.gilvum_PYR-GCK          MPSVTRKA---------------QATRQERREQIERRLLEATDRLMADGA
Mb3885|M.bovis_AF2122/97            MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLED-R
Rv3855|M.tuberculosis_H37Rv         MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLED-R
MLBr_00064|M.leprae_Br4923          MINSTAGQTS---------QSRSRRSTRPSGDDRELAILATAEQLLED-R
Mvan_5684|M.vanbaalenii_PYR-1       MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLAD-R
MAB_0984c|M.abscessus_ATCC_199      MTKPAT---------------RGRKTTRPSGDERIQAILATAEELLGK-R
TH_2600|M.thermoresistible__bu      MSKPRVRN--------------RYSSGPTRGEQRRERLLQALEDLLAS-R
                                    * .                            :     :* : : *: .  

MAV_1733|M.avium_104                SFTELSVDRLAGAAGISRASFYIYFEDKGHLLRRLASRVFGELTDGARRW
MSMEG_4622|M.smegmatis_MC2_155      SFTELSVDRLATEAGISRASFYIYFEDKGHLLRRLAAQVFDDLAHEAQQW
MMAR_3762|M.marinum_M               SFTELSVDRLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHW
MUL_3708|M.ulcerans_Agy99           SFTELSVDRLATEAGISRASFYIYFDDKGHLLRRLAGQVFDDLATGAQHW
Mflv_2639|M.gilvum_PYR-GCK          SITELSVDRLASEAGISRASFYIYFEDKGHLLRRLASQVFGDLADAAQRW
Mb3885|M.bovis_AF2122/97            PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
Rv3855|M.tuberculosis_H37Rv         PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
MLBr_00064|M.leprae_Br4923          PLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETL
Mvan_5684|M.vanbaalenii_PYR-1       SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
MAB_0984c|M.abscessus_ATCC_199      PLADVSVDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASI
TH_2600|M.thermoresistible__bu      PFAAIEVGDIARAAGLSRSAFYFYFPSKAAAVGAMLGDVFGEISDVLDKW
                                    .:: :.*. :*  **:**.:**:** .*   :  :   :. .        

MAV_1733|M.avium_104                WSVAGRHDPDD--VRAAMTRIIATYRRHQAVLVALNEMSGYDPLTAQTYR
MSMEG_4622|M.smegmatis_MC2_155      WGVAGRRNPGD--VHTAMSGIIASYRRHQPVLVALNEMSAYDPLVAQTYR
MMAR_3762|M.marinum_M               WDVAWRHDPDD--VRAAMRAIIARYRRHQPILIALNEMAGYDPQTAQTYR
MUL_3708|M.ulcerans_Agy99           WDVAWRHDPDD--VRAAMCAIIARYRRHQPILIALNEMAGYEPQTAQTYR
Mflv_2639|M.gilvum_PYR-GCK          WSVASRLDPED--VRVAMAAIIAAYRQHQPVLVALNEMAPYDPAVAETYR
Mb3885|M.bovis_AF2122/97            AENPADTDRENM-WRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWS
Rv3855|M.tuberculosis_H37Rv         AENPADTDRENM-WRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWS
MLBr_00064|M.leprae_Br4923          IKN-RDNKRGNK-WRTGINVFFETFGSHKAVTCAGQVTRDN-TEVRKLWS
Mvan_5684|M.vanbaalenii_PYR-1       IAE-RSSDRRTI-WRRGINVFFETFGAHRAVCATTVGVKSTNSEARELWS
MAB_0984c|M.abscessus_ATCC_199      DPA-AMTSPAQY-WRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRWS
TH_2600|M.thermoresistible__bu      TELGDSVAARRREVYDSFERVVAIWRQHAPLMAAMFDAASTDAEVRAMFE
                                                     :   .  :  * .:  :              : 

MAV_1733|M.avium_104                EILTGISGQLTRVIEDGQADGSIRPRLAAATTASALTWMVERACQQNLPA
MSMEG_4622|M.smegmatis_MC2_155      DLLTGISAQLARVIDEGQADGSIRAQLPAETTASTLTWMVERTCHQNLPS
MMAR_3762|M.marinum_M               DILTAISARLARVIEDGQADGSIRPELSATTTANALTWMVERTCHQNLPS
MUL_3708|M.ulcerans_Agy99           DILTAISARLARVIEDGQADGSIRPELSATTTANALTWMVERTCHQNLPS
Mflv_2639|M.gilvum_PYR-GCK          DLIAEISTRFEAVIVEGQKAGTIRPQLPPDITAHTLVLMVERTCQQNLPS
Mb3885|M.bovis_AF2122/97            TFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAG
Rv3855|M.tuberculosis_H37Rv         TFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAG
MLBr_00064|M.leprae_Br4923          TFMQKWISYTAAVIDAERKRGVAPDTLPATELATALNLMNERALFASFTA
Mvan_5684|M.vanbaalenii_PYR-1       RSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTATFTG
MAB_0984c|M.abscessus_ATCC_199      EVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFTG
TH_2600|M.thermoresistible__bu      GHIDSFVDGSAARIRHERAVGEAPDGPDPEALARVLVGMNVKALERDMRA
                                                 *   :  *       .   : .*  :        : .

MAV_1733|M.avium_104                -QPSAY-DAELADTLAEIVWGALYLKPASGS-
MSMEG_4622|M.smegmatis_MC2_155      -RPASY-DAELADTLTEIVWGALYLRPASTDR
MMAR_3762|M.marinum_M               -RPPEF-DAELADTLSEIVWGALYLTSTSLR-
MUL_3708|M.ulcerans_Agy99           -RPPEF-DAELADTLSEIVWGALYLTSTSLR-
Mflv_2639|M.gilvum_PYR-GCK          -RPTSF-DTELADVLTEIVWGSLYLTNPAG--
Mb3885|M.bovis_AF2122/97            EQPSVP-EARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv         EQPSVP-EARVLDTLVHIWVTSIYGENR----
MLBr_00064|M.leprae_Br4923          EQPHVP-ESRVLDTLVHIWVSSIYNEIR----
Mvan_5684|M.vanbaalenii_PYR-1       HQPAIP-DDRVLDNLVHIWTTSIYGKTD----
MAB_0984c|M.abscessus_ATCC_199      QQPAVD-DGKVVDTLLHVWLNAIYGGVCANS-
TH_2600|M.thermoresistible__bu      ITSGAPADADLPRVLAFVWGRVLYDA------
                                      .    :  :   *  :    :*