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M. leprae Br4923 MLBr_00815 (-)

annotation: putative TetR-family transcriptional regulator
coordinates: 963849 - 964535
length: 228

NNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASDVFVDHGYHAAGMDEIADRAGV
SKPVLYQHFSSKLELYLAVLERHMNNLVSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEND
NITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTNRPISKSDAVEG
TVQFAWGGLSHVPLTRL*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. leprae Br4923 MLBr_00815 - - 100% (228) putative TetR-family transcriptional regulator
M. leprae Br4923 MLBr_02568 - 7e-16 27.78% (198) putative TetR-family transcriptional regulator
M. leprae Br4923 MLBr_00717 - 2e-08 36.76% (68) putative TetR-family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3233 - 1e-106 82.38% (227) TetR family transcriptional regulator
M. gilvum PYR-GCK Mflv_4672 - 6e-93 76.21% (227) TetR family transcriptional regulator
M. tuberculosis H37Rv Rv3208 - 1e-106 82.38% (227) TetR family transcriptional regulator
M. abscessus ATCC 19977 MAB_3527 - 4e-81 67.10% (231) TetR family transcriptional regulator
M. marinum M MMAR_1350 - 1e-103 82.38% (227) TetR family transcriptional regulator
M. avium 104 MAV_4155 - 1e-104 81.50% (227) TetR-family protein transcriptional regulator
M. smegmatis MC2 155 MSMEG_1935 - 3e-92 75.44% (228) TetR-family protein transcriptional regulator
M. thermoresistible (build 8) TH_0452 - 1e-96 76.21% (227) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99 MUL_2529 - 1e-103 82.38% (227) TetR family transcriptional regulator
M. vanbaalenii PYR-1 Mvan_1795 - 3e-93 74.45% (227) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4672|M.gilvum_PYR-GCK          MSELAKTAPRRGGQPANGTGSS----GAARRGNRLPRDERRGQLLAAASE
Mvan_1795|M.vanbaalenii_PYR-1       MSEVARTAQRRGGQPANGASPS----GAARRGNRMPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu      MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MSMEG_1935|M.smegmatis_MC2_155      MSDLANTAERRGEKRPAG---------GNRRGNRLPRDERRGQLLIAASE
Mb3233|M.bovis_AF2122/97            MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv         MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MMAR_1350|M.marinum_M               MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
MUL_2529|M.ulcerans_Agy99           MSDLAKAAQHRAVRSADRVR-STEGATPKARGNRLPRDERRGQLLIVASD
MLBr_00815|M.leprae_Br4923          MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAV_4155|M.avium_104                MSELAKMPARRAVKSADRGRPTDGAAASNRRGNRLPRDERRGQLLVVASD
MAB_3527|M.abscessus_ATCC_1997      MRDLAKLAGRRGTVNSTVAT-QDSTQGNTRRGGRLPRDERRGQLVGSASE
                                    * ::*  . ::                   *..*:.**:**.**:  **:

Mflv_4672|M.gilvum_PYR-GCK          VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
Mvan_1795|M.vanbaalenii_PYR-1       VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu      VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MSMEG_1935|M.smegmatis_MC2_155      VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
Mb3233|M.bovis_AF2122/97            VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv         VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MMAR_1350|M.marinum_M               VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MUL_2529|M.ulcerans_Agy99           VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MLBr_00815|M.leprae_Br4923          VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MAV_4155|M.avium_104                VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKLELYLAVLARHVENLVS
MAB_3527|M.abscessus_ATCC_1997      IFVDRGYHAAGMDEIADRAGVSKPVLYQHFPSKLELYLAVLHKHADNLVS
                                    :***:***********:*************.**:******* :* ::**:

Mflv_4672|M.gilvum_PYR-GCK          GVRQALRTTTDNRQRVRAAVQAFFDFIEHDSQGYRLIFENDYVTEPQVAA
Mvan_1795|M.vanbaalenii_PYR-1       GVRQALRTTTDNRQRVRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVAA
TH_0452|M.thermoresistible__bu      GVRQALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVAA
MSMEG_1935|M.smegmatis_MC2_155      GVRQALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQVAA
Mb3233|M.bovis_AF2122/97            GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
Rv3208|M.tuberculosis_H37Rv         GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
MMAR_1350|M.marinum_M               GVQQALRTTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVAA
MUL_2529|M.ulcerans_Agy99           GVQQALRTTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVAA
MLBr_00815|M.leprae_Br4923          SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
MAV_4155|M.avium_104                GVQQALSTTKDNRRRLHAAVQAFFDFIEHDSQGYRLIFENDYVTEPEVAA
MAB_3527|M.abscessus_ATCC_1997      SVRQALRTTTDNRQRLRAAVMAFFDFVEHDSQGYRLIFENDLVGVPQVSE
                                    .*:*** **.:** *: .** *****:***.********** :  *.*: 

Mflv_4672|M.gilvum_PYR-GCK          QVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLNNE
Mvan_1795|M.vanbaalenii_PYR-1       QVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSARYWLNND
TH_0452|M.thermoresistible__bu      QVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLVAISVDCARYWLHAD
MSMEG_1935|M.smegmatis_MC2_155      QVKVATEACTDAVFDLISRDSGLEAHRARMIAVGLVAISVDSARYWLNND
Mb3233|M.bovis_AF2122/97            QVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDAD
Rv3208|M.tuberculosis_H37Rv         QVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARYWLDAD
MMAR_1350|M.marinum_M               QVRVATESCIDAVFALISADSGLDPHRARMIAVALVSMSVDCARYWLDSD
MUL_2529|M.ulcerans_Agy99           QVRVATESCIDAVFALISADSGLDPHRARMIAVALVSMSVDCARYWLDSD
MLBr_00815|M.leprae_Br4923          QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
MAV_4155|M.avium_104                QVRVATESCIDAVYALISEDSGLDPHRARMIAVGLVGISVDCARYWLDSD
MAB_3527|M.abscessus_ATCC_1997      RVEGAISACTDAVFDLVSHDSGLDPHHARMVAVGLVGISQVSARYWLDNE
                                    :*. * .:* ***: *:* ** *:.*:***:**.**.:*  .*****. :

Mflv_4672|M.gilvum_PYR-GCK          RPIDKDDAVEGTVQFIWGGLSHVPLTRS-
Mvan_1795|M.vanbaalenii_PYR-1       RPIDKDDAVEGTVQFIWGGLSHVPMTRS-
TH_0452|M.thermoresistible__bu      RPISKEDAVEGTVQFAWGGLSHVPLTRS-
MSMEG_1935|M.smegmatis_MC2_155      RPIDKDSAVEGTVQFAWGGLSHVPLTRS-
Mb3233|M.bovis_AF2122/97            KPISKSDAVEGTVQFAWGGLSHVPLTRS-
Rv3208|M.tuberculosis_H37Rv         KPISKSDAVEGTVQFAWGGLSHVPLTRS-
MMAR_1350|M.marinum_M               RPISKSDAIEGTVQFAWGGLSHVPLARS-
MUL_2529|M.ulcerans_Agy99           RPISKSDAIEGTVQFAWGGLSHVPLARS-
MLBr_00815|M.leprae_Br4923          RPISKSDAVEGTVQFAWGGLSHVPLTRL-
MAV_4155|M.avium_104                RPISKADAVEGTVAFAWGGLSHVPLTRS-
MAB_3527|M.abscessus_ATCC_1997      KPISKDDAVNATVGFAWGGLSHVPLQPHG
                                    :**.* .*::.** * ********:

species	id	gene	e-value	identity (len)	annotation
M. leprae Br4923	MLBr_00815	-	-	100% (228)	putative TetR-family transcriptional regulator
M. leprae Br4923	MLBr_02568	-	7e-16	27.78% (198)	putative TetR-family transcriptional regulator
M. leprae Br4923	MLBr_00717	-	2e-08	36.76% (68)	putative TetR-family transcriptional regulator