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GSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAIAAAAGVARGTFYFHFPTKEHV LVELERAEELAIVAKLRDPTADSTDLVSVLSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEH PLAEFVIETIAQAQRADRVAPDADAGELGVIFLTGLFALLATGATTPDARTALLNGFVTTVVHGMEAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4864 | - | - | 100% (209) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_3785 | - | 2e-07 | 31.68% (101) | putative regulatory protein |
| M. ulcerans Agy99 | MUL_4775 | - | 4e-07 | 30.06% (173) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 4e-07 | 28.31% (166) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1774 | - | 1e-43 | 43.88% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 4e-07 | 28.31% (166) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01070 | - | 3e-05 | 29.53% (149) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3565 | - | 7e-08 | 29.51% (183) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 1e-108 | 96.17% (209) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4190 | - | 9e-57 | 62.98% (181) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 8e-39 | 46.03% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1661 | - | 6e-43 | 46.00% (200) | transcriptional regulator, TetR family protein |
| M. vanbaalenii PYR-1 | Mvan_4973 | - | 1e-42 | 43.37% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4864|M.ulcerans_Agy99 ----MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGAD
MMAR_0249|M.marinum_M ----MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGAD
MAV_4190|M.avium_104 --------------------------------MFDAALAEISQRGLAAAD
Mflv_1774|M.gilvum_PYR-GCK ------------MTPQIKQSARELRRLQTRERILGAAIAEFQASGMAGAD
Mvan_4973|M.vanbaalenii_PYR-1 -----------MMAPQVRQTARELRRLQTRERILGAAIAEFQASGMAGAD
MSMEG_6604|M.smegmatis_MC2_155 ------------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADAD
TH_1661|M.thermoresistible__bu ------------MARAEKPSAREAKRLQTRERLLGAAIAEFKRTGMAEAD
Mb0068c|M.bovis_AF2122/97 ------------MAPTDRRVRADAARN--RARVLEVAYQTFAADGLS-VP
Rv0067c|M.tuberculosis_H37Rv ------------MAPTDRRVRADAARN--RARVLEVAYQTFAADGLS-VP
MAB_3565|M.abscessus_ATCC_1997 ----------MANRQTVQGVRTGGRSARVREAILDAAFGELIDRGYAELT
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFS
:: .* : .
MUL_4864|M.ulcerans_Agy99 VAAIAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADS-T
MMAR_0249|M.marinum_M VAAIAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADP-T
MAV_4190|M.avium_104 VSAIVADAGVARGTFYFHFPTKEHVLVEVERAEETRIVSELGGATG----
Mflv_1774|M.gilvum_PYR-GCK VGAIVSAAGVAHGTFFFHFPSKEHVLLELERREEARMATEFVRYLRRS-H
Mvan_4973|M.vanbaalenii_PYR-1 IGAIVSAAGVAHGTFFFHFPSKEHVLLELERREESRMATEFARYLDKK-H
MSMEG_6604|M.smegmatis_MC2_155 VGTIVAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQFAQFVKKP-H
TH_1661|M.thermoresistible__bu VRAIVAAAGVAHGTFFFHFPTKEHVLLELERREEERIARQFSRFLETE-H
Mb0068c|M.bovis_AF2122/97 VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSK-H
Rv0067c|M.tuberculosis_H37Rv VDEIARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSK-H
MAB_3565|M.abscessus_ATCC_1997 MEAVASRAGVNKTTIYRRWPTLEDLLVEALTTWSLEAIP-IPETGSIE-S
MLBr_01070|M.leprae_Br4923 VDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEALAEQLPA
: :. **: *.: :*: : ::
MUL_4864|M.ulcerans_Agy99 DLVSVLSSLAHQVVAVERR-LGPLVFRDMLGLHFAPTRPVEDQLGEHPLA
MMAR_0249|M.marinum_M DLVSVLSSLVHQVVAVERR-LGPVVFRDMLGLHFAPTRPVEDQLGEHPLA
MAV_4190|M.avium_104 DLAAVLNQLVQHVLSAEKR-LGPAVFRDMLGLHFCSTRPVEDELAQHPLG
Mflv_1774|M.gilvum_PYR-GCK DLTAALTKVVGLIAGLEQR-LGPVLFRELLALHFSPTRPSDDDWSDHPVI
Mvan_4973|M.vanbaalenii_PYR-1 DLASALAKVVELISALERR-FGPLLFKELLALHFSPTRPSTDEWSDHPVI
MSMEG_6604|M.smegmatis_MC2_155 DLEAALREIVRLVIGLERR-LGDLLFKDFLALHFSQTRPRVDEGMEHPVI
TH_1661|M.thermoresistible__bu DLVGTLKEAVRLVLDIEDR-LGPVLFKDFLALHFSPTRPPAEEGQDHPLI
Mb0068c|M.bovis_AF2122/97 PGDALFAFLRSMVLQWGATDRGLVEALAGVGIEISSAAP----EAEADFL
Rv0067c|M.tuberculosis_H37Rv PGDALFAFLRSMVLQWGATDRGLVEALAGVGIEISSAAP----EAEADFL
MAB_3565|M.abscessus_ATCC_1997 DLLSTGRELAAVLNDGVGR--QVAALVLTAGLRSAPLREATRRYFDHQVL
MLBr_01070|M.leprae_Br4923 DPAAVWRSAITAFFEVCGT-HRAVAVAGAAAKATSPEVRRLWSTVMQQWI
. . . .
MUL_4864|M.ulcerans_Agy99 EFVIETIAQAQRADRVAPDADAGELGVIFLTGLFALLATGATTPD---AR
MMAR_0249|M.marinum_M EFVIETIARAQRANRVPPDADAGELGVIFLTGLFALLATGATTPD---AR
MAV_4190|M.avium_104 QFLVGVIGRAQDAGQVASDVDAAELATFFLTGLFALLATGAHDG------
Mflv_1774|M.gilvum_PYR-GCK VSLVREIERARGDGEVHPEVDAFFSAAFFLLGVYGVLTT-VTSSD---TR
Mvan_4973|M.vanbaalenii_PYR-1 VSLVGAIERARGDGEIHPEVDAFYSAAFFLLGIYGVLTT-VARGD---IR
MSMEG_6604|M.smegmatis_MC2_155 ARVTEEIEAARQRGDVAADVNPVNSAVFFLLGFYALLVT-TNDWP---TR
TH_1661|M.thermoresistible__bu VSVAEEIERAQRAGEVDAEVNPWNSAVFFLLGLYALLTT-THAWP---NR
Mb0068c|M.bovis_AF2122/97 DLLTDLLRAAQRAGTVRPDVDVLEVKT-LLVGCQAMQSY----------N
Rv0067c|M.tuberculosis_H37Rv DLLTDLLRAAQRAGTVRPDVDVLEVKT-LLVGCQAMQSY----------N
MAB_3565|M.abscessus_ATCC_1997 R-AAPVVRQAIDRGELPADCDVDMLLTTFRAPLFYRTIT--TGDP---ID
MLBr_01070|M.leprae_Br4923 DYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPD
: . . :
MUL_4864|M.ulcerans_Agy99 TALLNGFVTTVVHGMEAR----
MMAR_0249|M.marinum_M TALLNRFVTTVVHGMEAR----
MAV_4190|M.avium_104 -ALLSHYVTTIVKGMEKR----
Mflv_1774|M.gilvum_PYR-GCK DAMLANLITTARRGLESR----
Mvan_4973|M.vanbaalenii_PYR-1 DAMLANLITTARRGLETR----
MSMEG_6604|M.smegmatis_MC2_155 DEVLDDYVRRTLRSMRP-----
TH_1661|M.thermoresistible__bu AGMVDDFVANTLRSLRPRLTRR
Mb0068c|M.bovis_AF2122/97 AELAAKVTDVALDGLRANRK--
Rv0067c|M.tuberculosis_H37Rv AELAAKVTDVALDGLRANRK--
MAB_3565|M.abscessus_ATCC_1997 DALIIHATQITLTAARAGLLSA
MLBr_01070|M.leprae_Br4923 KKVIDTLVHIWLASIYGS----
: .