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MGSPGTSSIGRPRSFDTDEALERAMVVFWAHGYEGASLTDLTEAMGITRTSMYAAFGNKEELFRAALTRY LEGPGGYLSRALEESTAREVAEAFLRGSVRATTRPEGPAGCLVVQGSLAASDAGQPVRDALIACREEAVS RLRERFRRAVKDGDLPPGTDPGLLARYLMTVGNGIAVQAASGVARRELQRVADAALRHWPPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1617 | - | - | 100% (202) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5842 | - | 1e-41 | 46.63% (193) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5917 | - | 4e-15 | 26.32% (190) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 1e-05 | 23.24% (185) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0944 | - | 5e-17 | 27.27% (187) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 1e-05 | 23.24% (185) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 5e-05 | 30.00% (60) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0901c | - | 5e-09 | 29.89% (174) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0630 | - | 3e-13 | 27.37% (190) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 3e-09 | 30.72% (166) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5597 | - | 4e-46 | 48.44% (192) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0258 | - | 1e-07 | 28.57% (196) | transcriptional repressor, TetR family protein, putative |
| M. ulcerans Agy99 | MUL_1163 | - | 1e-06 | 22.99% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0244|M.bovis_AF2122/97 ---------------------------MAGGTKRLPRAVREQQMLDAAVQ
Rv0238|M.tuberculosis_H37Rv ---------------------------MAGGTKRLPRAVREQQMLDAAVQ
MUL_1163|M.ulcerans_Agy99 ---------------------------MAGGTKRLPRAIREQQMLDAAVQ
Mvan_1617|M.vanbaalenii_PYR-1 ------------------------MGSPGTSSIGRPRSFDTDEALERAMV
MSMEG_5597|M.smegmatis_MC2_155 --------------------------------MGRHREFDVDKALDAALC
Mflv_0944|M.gilvum_PYR-GCK --------------------------------MARPRTFDEDEVIEAGRD
MMAR_0630|M.marinum_M --------------------------------MARPRAFDEAVVLSAARD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
MAB_0901c|M.abscessus_ATCC_199 ----------------------MTTPRTRPSRQVGRPGYDLDSLLAVAVS
TH_0258|M.thermoresistible__bu -------------------VSRADGGQRRASYQRARSRETKRALVQAAMA
: .
Mb0244|M.bovis_AF2122/97 MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFID
Rv0238|M.tuberculosis_H37Rv MFSVNGYHETSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFID
MUL_1163|M.ulcerans_Agy99 MFSANGYHETSMDTIAAAAQISKPMLYLYYGSKEDLFGACLNREMSRFID
Mvan_1617|M.vanbaalenii_PYR-1 VFWAHGYEGASLTDLTEAMGITRTSMYAAFGNKEELFRAALTRYLEGPGG
MSMEG_5597|M.smegmatis_MC2_155 VFWRKGYEGASYSDLTQATGVERPALYSAFGNKEALFLRALDRYYERYMD
Mflv_0944|M.gilvum_PYR-GCK LFWSQGYAATSIDDLSAATGLGRGSLYKAFGDKHSMFLRGLEQYCTEAIA
MMAR_0630|M.marinum_M EFRSHGYAATSVDSLAAATGLNRSSLYGSFGDKHRLFLRALDGYCEATLH
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
MAB_0901c|M.abscessus_ATCC_199 VFNQRGYDGTSMEHLSTRLGISKSSIYHHVSGKEELLRLAVDRALDALFA
TH_0258|M.thermoresistible__bu LWRTNGYANTTVADICRAAGVSRALFYFYFPAKEDILFEVGLLSTQAARR
: .*: : : . : .* * :
Mb0244|M.bovis_AF2122/97 ALRSSINFD-----QSPKDLLRNTIVSFLRYIDAN-----RASWIVMYTQ
Rv0238|M.tuberculosis_H37Rv ALRSSINFD-----QSPKDLLRNTIVSFLRYIDAN-----RASWIVMYTQ
MUL_1163|M.ulcerans_Agy99 AVRADIDLS-----QSPKDLLRNAIVSFLRYIDQN-----QASWIVMYTQ
Mvan_1617|M.vanbaalenii_PYR-1 YLSRALEES--TAREVAEAFLRGSVRATTRPEGPAGCLVVQGSLAASDAG
MSMEG_5597|M.smegmatis_MC2_155 FIPVALEQP--TSREVAEHLLRSAADLNTRYPDHTGCLGVQGCLVGTDDS
Mflv_0944|M.gilvum_PYR-GCK GIRAELRDQDLSAYDRLVAHVRGRAADVVSDNDLRGCLLAKSAAELSSTD
MMAR_0630|M.marinum_M DVREVLRERGVSARQRLINHVHAIVNGIVADTDRRGCMMSRSSAELAGAD
MLBr_00815|M.leprae_Br4923 SVQQALRTT-----TNNRQRLHAAVQAFFDFIEHDG----QGYRLIFEND
MAV_1611|M.avium_104 QIAIALDRSAGDTTAAAREVSRSVLDSVRDHSDYY--VLLVEYWLRAQRD
MAB_0901c|M.abscessus_ATCC_199 ATEAPDTTTG-PAIDRLENLVKRSIQVLVQELPYVT------LLLRIRGN
TH_0258|M.thermoresistible__bu RIRSLLRGD-----YDVDSVIAAALRSLERSMARNPRELIVQTILEGYRH
Mb0244|M.bovis_AF2122/97 ATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEM-MAVALVGA
Rv0238|M.tuberculosis_H37Rv ATSSQAFAHTVREGREQIVQLVAELVRAGTRGPLTDAEIEM-MAVALVGA
MUL_1163|M.ulcerans_Agy99 AVSSQAFAQTVREGREQIVELVAGMLRAGTRSPRSDAEIDM-MAAALVGA
Mvan_1617|M.vanbaalenii_PYR-1 QPVRDALIACREEAVSRLRERFRRAVKDGDLPPGTDPGLLA-RYLMTVGN
MSMEG_5597|M.smegmatis_MC2_155 EPIRRALVDARASGEASLRARFEDAHATGDLPKSANPAALA-AFLMTVLH
Mflv_0944|M.gilvum_PYR-GCK PEVARHVKRTLDAWLRELTATISAAQADGDIPSSTEAKALA-ALILAVLR
MMAR_0630|M.marinum_M PDVSGIVERSLEAWRRELADCIAEAQLEGAVAGDGSPQALA-TVMLSLMQ
MLBr_00815|M.leprae_Br4923 NITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVA-VGLVGISV
MAV_1611|M.avium_104 PQLRERLIERRRAAADQALHIVESTDTVPGDRRLTDIAQLV-VTLNLGVA
MAB_0901c|M.abscessus_ATCC_199 TAAERRALARRREFDDIVGNLVEEACNEGSIRAGVDPALTS-RLIFGTVN
TH_0258|M.thermoresistible__bu EHRILAGEEDPATGADMFGELFTRAQQDGKLAAGIDVDHLSRVAQMLVSE
.
Mb0244|M.bovis_AF2122/97 GEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDR-LETGH---
Rv0238|M.tuberculosis_H37Rv GEAVATRLGIGDTDVDEAAEMMINLFWLGLKGAPVDR-LETGH---
MUL_1163|M.ulcerans_Agy99 GEAVANRLSAGDTDVDEAAEMMIDLLWRGLKGAPSDREIGSNFAAG
Mvan_1617|M.vanbaalenii_PYR-1 GIAVQAASGVARRELQRVADAALRHWPPA-----------------
MSMEG_5597|M.smegmatis_MC2_155 GMAVQAKAGFSRETLDAIIDQALSSWPTPDRGSAGKATRKR-----
Mflv_0944|M.gilvum_PYR-GCK GMEALRKGGASAATVKATAEQLVAML--------------------
MMAR_0630|M.marinum_M GFEALGKGGVGSAELRAAESAALALLFGAGTDPKP-----------
MLBr_00815|M.leprae_Br4923 DCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL--------
MAV_1611|M.avium_104 MEEVLRPGTINPDLLAQLITALLESIPV------------------
MAB_0901c|M.abscessus_ATCC_199 SLIEWYR-PSRTLSADEVADAVATMIFDGLRTRSGQH---------
TH_0258|M.thermoresistible__bu GVRHWAAGGFGDRSFTEVVAGDIAALIDGYNLRLRR----------