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SGASERSIDDPHVAGFLATARSQPAGLVIEGEAGIGKTTLWLTVRQRAGDLGFRVLTARAGQAESVMAFA ALADLLDDVGDEVFAQLPGLQRLALDRVLLRAGGDGPPTDQRVVAAAFVSVLQALAGESPVLIAIDDAQW LDSSSRAAIEFAVRRLRGPFGVLVTERCAPGEGATAGWLKLDRPDALERVYVRPMTTGQLHSLISERLGR TLARPSILRIAEISGGNPFFALELALALSDGQGSGEPPLPATLADVVRHRIGRLDEQTRSVLLSIACVAD ATVELLARAHDVTAEEVTERLERVESTGIITVEGNRVRFTHPLLASGVYTDAGPTARRAMHRTMGALESQ PELKARHLALASASGDDEIFTALDQAADSARARGAPAAAAELMDLAIGLGADDPLRRMKSAENHFLAGDT AKAAAALGRIDTIEPPVLRALAASLLATVRMYENEHTEAVELLRGALDDGAGNVPILVQVLLRLSFALNS IGDLDDAARYVRDAVKLAEELGVPGIISAALAWSVHVNIQCGRGLDEESLRRAMELYDSTLDVPIIFRAP FVHALVMSWTGRLEQAHRELTAMRAVCVERGAESDMMAIAGFLAINHLWRGQIAEAEAEASEAVERAEQL GGDDVLIIPMTVRGTLAAYAGRVEDARADARWVLDAVKNRQTSHIADWPGMTLCFLEESLRNHREALQAL DAKFLDPKQMRSTELMYAWHLPDVIEAMVGVGRLDEAESLTGALEQNGIEHDRHWMKAVGMRCRAMLLAA RGDVIAAEQTAHRAMAEHDRLPMPFERARTQLLLGQLQRRLRQKNTAATNLNEALRTFEEMGTPLWVRRA RAELARAVVAPAEGLSQLTPSEQRVAEMAASGATNKDIASAMFISAKTVEHNLTKIYRKLGISSRAELGR RMDRAGEP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1863 | - | - | 100% (919) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5653 | - | 0.0 | 48.48% (922) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5449 | - | 2e-58 | 28.32% (925) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0914c | - | 3e-15 | 22.70% (489) | LuxR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4504 | - | 0.0 | 77.50% (920) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0890c | - | 5e-15 | 22.70% (489) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01753 | - | 8e-10 | 44.83% (58) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3361 | - | 2e-54 | 27.85% (937) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 6e-52 | 26.84% (935) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 3e-18 | 24.83% (596) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_6828 | - | 8e-63 | 29.38% (953) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3931 | - | 1e-105 | 41.19% (573) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 8e-19 | 27.13% (564) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1863|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --------------------------------------------------
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
Mvan_1863|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --------------------------------------------------
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
Mvan_1863|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4504|M.gilvum_PYR-GCK --------------------------------------------------
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M --------------------------------------------------
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDVNNVVFMMVQAAGL
MSMEG_6828|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
Mvan_1863|M.vanbaalenii_PYR-1 --------------------------------------------MSGASE
Mflv_4504|M.gilvum_PYR-GCK --------------------------------MRAALPAAMMNAMSDASP
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M -----------------------------------------MPTVTLVGR
Mb0914c|M.bovis_AF2122/97 --------------------------------------------------
Rv0890c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01753|M.leprae_Br4923 LDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQLC
MSMEG_6828|M.smegmatis_MC2_155 -----------------------------------------------MVG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ------------------------------------------MIGGELLI
Mvan_1863|M.vanbaalenii_PYR-1 RSIDDPHVAGFLATARSQPAGLVIEGEAGIGKTTLWLTVRQRAGDLGFRV
Mflv_4504|M.gilvum_PYR-GCK QAADDPQVAGFLCTATSAPTGLIIEGDAGIGKTTLWLSLLQTARMRGFQV
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ----------------------MLRGQAGVGKTALLRYVLGKAS--GQLI
MMAR_0085|M.marinum_M HREQQQLQQLLDAARRGESGVLVLRGDAGIGKTTLLTDLVDNAP--DLRV
Mb0914c|M.bovis_AF2122/97 --------------------------------------MRALLAQNRLVT
Rv0890c|M.tuberculosis_H37Rv --------------------------------------MRALLAQNRLVT
MLBr_01753|M.leprae_Br4923 HRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKRLLT
MSMEG_6828|M.smegmatis_MC2_155 RSEELAAVTDVLADISTGGAALVIDGDPGIGKSTLLAAASDWAVANGYAR
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 GRDSELAAIRRALNGADHHRGVVIAGAAGVGKTWLARAALRRAGASGEQI
Mvan_1863|M.vanbaalenii_PYR-1 LTARAGQAESVMAFAALADLLDDVGDEVFAQLPGLQRLALDRVLLRAGGD
Mflv_4504|M.gilvum_PYR-GCK LTARVGQAESVMAFAALADLLGAVSDEHFAALPPLQRLALDRVLLRAGAD
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AQASGIQSEMELAFAGLQQFCAPL-TKYSGAIPDPQREALTIAFGTR--S
MMAR_0085|M.marinum_M LRVRGAEMEMELTYSGVQQLCGPL-MSLIGQLPEPQLDALEIALGRK--R
Mb0914c|M.bovis_AF2122/97 LCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATAARAV
Rv0890c|M.tuberculosis_H37Rv LCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATAARAV
MLBr_01753|M.leprae_Br4923 LVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT-----
MSMEG_6828|M.smegmatis_MC2_155 LGCSGLQSQMEIGYAGLHELLHPLLAQVDALPPR-QRAALMTAFGLE--D
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 KWIVGTQSAQALPLGAFIGLLGDAMSEPLTSVRR----------------
Mvan_1863|M.vanbaalenii_PYR-1 GPPTD---------QRVVAAAFVSVLQALAGESPVLIAIDDAQWLDSSSR
Mflv_4504|M.gilvum_PYR-GCK GPATD---------QRVVAAGFVSLLHILAADAPVLIAIDDVQWLDASSR
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GPPPD---------RFLIGLAVLSLLAAAAEHQPVLCVIDDAQWLDRVSL
MMAR_0085|M.marinum_M GRAPD---------RLLLGLAVLTLVGEASRASPILCVVDDAQWVDSASV
Mb0914c|M.bovis_AF2122/97 GLPDQPGRSTMDSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPE
Rv0890c|M.tuberculosis_H37Rv GLPDQPGRSTMDSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPE
MLBr_01753|M.leprae_Br4923 ---------VLDNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLLGACPS
MSMEG_6828|M.smegmatis_MC2_155 GPPPD---------RMLIGLSVLGLLEEAAGNRRLFLVIDDAQWLDPSSV
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ---------------------VIETFVARQRRGRVVVGVDDAHLLDGLSA
Mvan_1863|M.vanbaalenii_PYR-1 AAIEFAVRRLRGPFGVLVTERCAPGEGATAGWLKLDRPDALERVYVRPMT
Mflv_4504|M.gilvum_PYR-GCK TAIEFAVRRLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPPMD
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 QTLAFVTRRLGSEPVAMLFAVRDGTDSELAGLPELTVHG---------LR
MMAR_0085|M.marinum_M QALAFVARRIHVDPVAMVFATRDRGPDALTGHCELSLQG---------LE
Mb0914c|M.bovis_AF2122/97 LTILATSREPIGMAGEITWRVPSMSITDEAVELFADRASRVQPG----FT
Rv0890c|M.tuberculosis_H37Rv LTILATSREPIGMAGEITWRVPSMSITDEAVELFADRASRVQPG----FT
MLBr_01753|M.leprae_Br4923 LTILATSREPIGVAGEVIWRVSMLSPADEAVELFTERAALVQPG----FS
MSMEG_6828|M.smegmatis_MC2_155 DVLNFVARRLSNAPLMMLCSTRTTLDGFSVQFDGLPRLTMG------PLE
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LVVHQLAQSGGVRLVVTVRTGSHQPDAVTALWKDDLLTRLDLEP----LS
Mvan_1863|M.vanbaalenii_PYR-1 TGQLHSLISERLGR-----TLARPSILRIAEISGGNPFFALELALALSDG
Mflv_4504|M.gilvum_PYR-GCK AGRLHALISHRLGR-----TLTRPVVLRIAEMSGGNPFYALELAHTHVNS
TH_3931|M.thermoresistible__bu ------VLLARLGR-----TFPRAVMVQIHHISGGNPFYALELARAMDDG
MAB_3361|M.abscessus_ATCC_1997 AADAGTLLDSVIPG-----LLDERVRDRIVAETQGNPLALLELPRDMTAE
MMAR_0085|M.marinum_M DHDARLVLSTAIPG-----RLNDSVAETVLAEANGNPLALLELHNALIRG
Mb0914c|M.bovis_AF2122/97 IANHNAAAVGEICR-----RLDGIPLAIEFAAARVRSMSPLEIADGLDDC
Rv0890c|M.tuberculosis_H37Rv IANHNAAAVGEICR-----RLDGIPLAIEFAAARVRSMSPLEIADGLDDC
MLBr_01753|M.leprae_Br4923 VTDGNRQIVTEICQ-----RLDGMPLAIELAAARIRTLSLTEIADGLDDR
MSMEG_6828|M.smegmatis_MC2_155 PADAAELLALTLRDPERSDRVDEVARQRILEQANGNPMAVIELTIALIES
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 AAATREVIESTLGG-----PVDARCAARFRRLTGGNTLFLRQLLSDQMAA
Mvan_1863|M.vanbaalenii_PYR-1 ----QGS------GEPPLPATLADVVRHRIGRLDEQTRSVLLSIACVADA
Mflv_4504|M.gilvum_PYR-GCK ----GDSP---PAAEPPLPATLADVVRRRVGLLDDATRTLLLGVACVADP
TH_3931|M.thermoresistible__bu ----SPL--------VRLPSSLTELVRARIGRIGADARNVLLAAACSAAP
MAB_3361|M.abscessus_ATCC_1997 ----ELAGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLG
MMAR_0085|M.marinum_M ----ELAGGYGLANATRTETQIERTFVSRLRALPSETKTFLLVAAAESTA
Mb0914c|M.bovis_AF2122/97 ----FRLLAGGVRGAVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGG
Rv0890c|M.tuberculosis_H37Rv ----FRLLAGGVRGAVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGG
MLBr_01753|M.leprae_Br4923 ----FRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGT
MSMEG_6828|M.smegmatis_MC2_155 ----GDGAPIFAGEPLPTTRRVERAFLTQLGPLSDESRLLLLLIATGN-G
MUL_2555|M.ulcerans_Agy99 ---------------------MPALSANLVASIDRHPERITLRCDDLQSV
MAV_0578|M.avium_104 GRMRRVAGVWMWDGDVAVSASLSDTVGRQLGRLTPPLALVVDTLSQCEPL
: : .
Mvan_1863|M.vanbaalenii_PYR-1 TVELLARAHDVTAEEVTERLERVESTGIITVEGNRVRFTHPLLASGVYTD
Mflv_4504|M.gilvum_PYR-GCK TVELLARAHGASTDEITAGLERAEAAGIVVLEGNRVRFTHPLLAGGVYTD
TH_3931|M.thermoresistible__bu TVESVARAVGVDEPRVVRLLSDAVDRDIIRMDGHRICFSHPLLARGVYDD
MAB_3361|M.abscessus_ATCC_1997 DVTLLARAAQQLG-IPMHAIAPAEAADLVELST-RVRFRHPLVRSAVYIS
MMAR_0085|M.marinum_M RPEWLWAAAHRLG-IGPEAAAPAEAAGLIAAQG-SVRFRHPLIRAAVYHS
Mb0914c|M.bovis_AF2122/97 FDLAAVRAVAAGS----DLDPFSVLDQLTLLVDKSLVVADDCQGRTRYRL
Rv0890c|M.tuberculosis_H37Rv FDLAAVRAVAAGS----DLDPFSVLDQLTLLVDKSLVVADDCQGRTRYRL
MLBr_01753|M.leprae_Br4923 FDLKVAYAVGHDD----LEEPDQVFDRLTMLIDKSLVIVEGRQGGSRYRL
MSMEG_6828|M.smegmatis_MC2_155 LLSEIDWAADHLGFSLTEHLGSLEESGLITVAGGRIQIRHPLIRSTVYGA
MUL_2555|M.ulcerans_Agy99 FAELGAGPGDRVAALPGDRTRRRVCGPACELSGGRFRPSARPQSCPGLTE
MAV_0578|M.avium_104 PVDLLCDLASREDLVAAEAMG--LVTVERTPRALMARLAHPLFGELRRAG
Mvan_1863|M.vanbaalenii_PYR-1 AGPTARRAMHRTMGALES---QPELKARHLALASASGDDEIFTALDQAAD
Mflv_4504|M.gilvum_PYR-GCK AGPTARRAMHRAIASVES---HPELRARHLALAASSGDDEIFAALDQAAD
TH_3931|M.thermoresistible__bu ATATRRRAMHRRLAEIVD---EPELQARHLAIAVGWADPQVLACLDRAAE
MAB_3361|M.abscessus_ATCC_1997 ANPLERRRIHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAWELEQSAG
MMAR_0085|M.marinum_M SSAAERRRVHAALAASIAGPDDDDHRVWHRAHAAEAPDAQTADDLERSAE
Mb0914c|M.bovis_AF2122/97 LETVRRYALEKLGDSGEAD-VHARHRDYYTALAASLNTPADNDHQRLVAR
Rv0890c|M.tuberculosis_H37Rv LETVRRYALEKLGDSGEAD-VHARHRDYYTALAASLNTPADNDHQRLVAR
MLBr_01753|M.leprae_Br4923 LETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDIDHEQLVEQ
MSMEG_6828|M.smegmatis_MC2_155 AALASRAAVHRALAAAAT---DPARAAWHRAEAAFGPNEEVAADLERVAD
MUL_2555|M.ulcerans_Agy99 AASPGR-------------------------------SRGPLHLARCAAE
MAV_0578|M.avium_104 AGEMYLSTIRGRLATRLAQ--DQDADMQATVRRALLTLESDLDPQPELYL
Mvan_1863|M.vanbaalenii_PYR-1 SARARGAPAAAAELMDLAIGLGADDPLR---RMKSAENHFLAGDTAKAAA
Mflv_4504|M.gilvum_PYR-GCK SARARGAPAAAAELMDLALGLGAHDPMR---RLKAAENHFLAGDTAKAAA
TH_3931|M.thermoresistible__bu AARLRGAPSTAAELIDMAIGLGGDSPER---RLMSARNHVDAGDGDSARA
MAB_3361|M.abscessus_ATCC_1997 RAQAKGGVLAAAAFLQRATELTADPAARGRRALAAAQSKYDAAAFDAARE
MMAR_0085|M.marinum_M RARARGGLSAAASFLEHATKLTPDPFVRASRALDAAMTSLEAGMPDSATR
Mb0914c|M.bovis_AF2122/97 AETEIDNLRAAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNS
Rv0890c|M.tuberculosis_H37Rv AETEIDNLRAAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNS
MLBr_01753|M.leprae_Br4923 VETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDS
MSMEG_6828|M.smegmatis_MC2_155 RARVRGAGAEAAAALRRAAALTDDPQERLRRMTVAAEVARSSGLIAESVR
MUL_2555|M.ulcerans_Agy99 LTIRRGDACQAIELLRRAGELSDRPRRREQLLASAAFVALQAAQLDEAER
MAV_0578|M.avium_104 ESARHAMTLLDLDLADRLANAAARAGAPGAAGVRAMNLVLLGRGEQAEEA
Mvan_1863|M.vanbaalenii_PYR-1 ALGRIDTIEPPVLRALAASLLATVRMYENEHT----------------EA
Mflv_4504|M.gilvum_PYR-GCK ALGEVGSIEPPILRAMATSLLATVRMYDNEHR----------------QA
TH_3931|M.thermoresistible__bu ILKRSSAEMTGAPRAQVLRLLGGLEILYGSYL----------------DA
MAB_3361|M.abscessus_ATCC_1997 LLGVADMTPLDPLARARATRLRAKIAFAESRVGAFGSVTVSEAAIGLVEA
MMAR_0085|M.marinum_M LVASAAAAADDELIAARCELIRAKIAFAASRG--------SDAPPLLLAA
Mb0914c|M.bovis_AF2122/97 ILEDQRFHRLAVSTAVRARALADKAMLSTWLAT------------SPVGA
Rv0890c|M.tuberculosis_H37Rv ILEDQRFHRLAVSTAVRARALADKAMLSTWLAT------------SPVGA
MLBr_01753|M.leprae_Br4923 IFEHKNIEHLVAPKEVLARAVANKVMLHAILAS------------SPPDG
MSMEG_6828|M.smegmatis_MC2_155 ILREAEPLIREHESETPLAITRFVLNATAATPG---------------QS
MUL_2555|M.ulcerans_Agy99 LLADAGLGGGASASALLISSFISLYRYGDVTAT-----------------
MAV_0578|M.avium_104 LRAITDGADGDASDRHYWATVRAANLVWMLGRP-----------------
Mvan_1863|M.vanbaalenii_PYR-1 VELLRGALDDGAGNVPILVQVLLRLS--FALNSIGDLDDAAR-YVRDAVK
Mflv_4504|M.gilvum_PYR-GCK VDLLRSALDDAADNVPVQVQVLLRLS--FALNSIGELDDARR-YARDAVK
TH_3931|M.thermoresistible__bu ADALRRALTDATDDAVLRARILTLLA--FVEFNTGRRAAAAA-DADEAVE
MAB_3361|M.abscessus_ATCC_1997 ARCLENLDDNLARETYLDAVGAAMYGGRLCP--RGGAVEVAE-PARLAPA
MMAR_0085|M.marinum_M AQRMQRLDPSESRKAYLGAVLASILVGRMATDQHNSSPSVAK-AASNAPA
Mb0914c|M.bovis_AF2122/97 TDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATD
Rv0890c|M.tuberculosis_H37Rv TDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATD
MLBr_01753|M.leprae_Br4923 SDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVE
MSMEG_6828|M.smegmatis_MC2_155 ADELLALSRKIADDDPGRRQLLWAAAIECRMHGLPEHS-----RRDVVAE
MUL_2555|M.ulcerans_Agy99 --HRRLVERLQSADDLDGETLTRMVNLLLAVSMFAADPALWQITDGLVDS
MAV_0578|M.avium_104 -ADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAERARAALD
: .
Mvan_1863|M.vanbaalenii_PYR-1 LAEELGVPGIISAALAWSVHVNIQCGRG-LDEESLRRAMELYDSTLDVPI
Mflv_4504|M.gilvum_PYR-GCK LAEELGFPGATSAALAWAVHVDFQCGRG-LDETALARAMKLYDSTFDVPI
TH_3931|M.thermoresistible__bu CATRAGDRGVLSQALAMRTLVTCLLGRG-FDPAALHRALELEEPGSGDLG
MAB_3361|M.abscessus_ATCC_1997 GAQPARPSDLLLDGLARRITHGAAASAQ-TLGEALTLIRCEADR-PANTS
MMAR_0085|M.marinum_M APHPPRALDVLLDGLVIRLTEGYVAAAP-RLRSAIREYLRERDIGVAEPG
Mb0914c|M.bovis_AF2122/97 LARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFV
Rv0890c|M.tuberculosis_H37Rv LARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFV
MLBr_01753|M.leprae_Br4923 LARTQGDKWTLSQIRLWGVVGFCVSGDPVALRAAAEAADDLAQEIGDRFV
MSMEG_6828|M.smegmatis_MC2_155 IGRLDDDPHDPLTAIALALADDTGKGAG-----LRARLPQLVDTVGDSPL
MUL_2555|M.ulcerans_Agy99 LADRLGELSVIYRDAWADAARRGR--------TVTQRLKEQLDRLAELEP
MAV_0578|M.avium_104 SESLP-DFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEASHM
Mvan_1863|M.vanbaalenii_PYR-1 IFRAPFVHALVMSWTGRLEQAHRELTAMRAVCVERGAESDMMAIAGFLAI
Mflv_4504|M.gilvum_PYR-GCK IFRAPFVHALAMSWTGRLEQAHQELTAVRGVCLERGAESDMMAIAGFLAI
TH_3931|M.thermoresistible__bu ITRTSGLHAMLLAYTGRFDAAVEVMRAVARHCRDRGEGLDLTYIALHRVL
MAB_3361|M.abscessus_ATCC_1997 WMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVG--ALSLLPAALI
MMAR_0085|M.marinum_M WHDLTARVCLD-----LFDQDAYNFLAARQVEDLRAAG--ALTMLPVALV
Mb0914c|M.bovis_AF2122/97 SRHCSLWLSLAQMWAGNLTEALELSREITAEAEASNDVPTKVLGLYTQAQ
Rv0890c|M.tuberculosis_H37Rv SRHCSLWLSLAQMWAGNLTEALELSREITAEAEASNDVPTKVLGLYTQAQ
MLBr_01753|M.leprae_Br4923 SLQCRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTR
MSMEG_6828|M.smegmatis_MC2_155 LMLS---LAFAAEAVTDRAGALKCWTHVQNQARNCGSLAEECEGLRGAAN
MUL_2555|M.ulcerans_Agy99 WDVMR--VALAGYYVDLIDDFRSVLVPLADREIEGGAATIALATLALVAA
MAV_0578|M.avium_104 RFWFGAVYGRACRLTGRIDEFVSTARRLADSAR-DVPGLAYANLALLLGN
Mvan_1863|M.vanbaalenii_PYR-1 NHLWRGQIAEAEAEASEAVERAEQLGGDDVLIIPMTVRGTLAAYAGRVED
Mflv_4504|M.gilvum_PYR-GCK NHLWRGQITDAEAEAAEAVERAEQLGGDDVLIIPMTVRGAIAAYAGRVDD
TH_3931|M.thermoresistible__bu VELWRGEVRAAATIAEEAIESAAVLDGDLPRGVVLLLRQALATYAGRVDD
MAB_3361|M.abscessus_ATCC_1997 YRAGMHVHAGELDAAAELVQEADAISAATGHAPIRYHSLILAAWRGSEPT
MMAR_0085|M.marinum_M TFAGVCVSAGNFGQADALLDESAAIIAATGAPPRPAIKTYLAAYRGQEQI
Mb0914c|M.bovis_AF2122/97 VLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAAL
Rv0890c|M.tuberculosis_H37Rv VLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAAL
MLBr_01753|M.leprae_Br4923 ALVHRDVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAV
MSMEG_6828|M.smegmatis_MC2_155 ILLTEGHVEAAAMSAQTALHMAESMNIAMTAGSAAAILARALVWQGQGER
MUL_2555|M.ulcerans_Agy99 YQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRGYLGVISACRGDVVR
MAV_0578|M.avium_104 AELARGAAAEAARLVQEALAGAQIHEVTSGLRPASYFALAEAHGRLGHPA
Mvan_1863|M.vanbaalenii_PYR-1 ARADARWVLDAVKNRQTSHIADWPGMTLCFLEESLRNHREALQALDAKF-
Mflv_4504|M.gilvum_PYR-GCK ARADARWVLAAVRNRKASHIADWPGMTLCFLEESLGNHREALAALDDSF-
TH_3931|M.thermoresistible__bu ARGDGARAAAIFARSGSAILTTLTTSLTGFLELSVGDHVAAIATLRPLLP
MAB_3361|M.abscessus_ATCC_1997 AIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRAC-
MMAR_0085|M.marinum_M CREGVQQTVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGA-
Mb0914c|M.bovis_AF2122/97 EASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATN-
Rv0890c|M.tuberculosis_H37Rv EASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATN-
MLBr_01753|M.leprae_Br4923 EASEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATT-
MSMEG_6828|M.smegmatis_MC2_155 ARHVLDRARHHLSPAPTILWNDDVHWAAGLAALCEADHTQALGHLTQMT-
MUL_2555|M.ulcerans_Agy99 ARELAAQVRVWAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAIT-
MAV_0578|M.avium_104 QANEAIAGARSCVPPDFLFMHTGLALATGWALAAGGQLREAVATAQAAAR
*
Mvan_1863|M.vanbaalenii_PYR-1 LDPKQMRSTELMYAWHLPDVIEAMVGVGRLDEAESLTGALEQNGIEHDRH
Mflv_4504|M.gilvum_PYR-GCK IAAG-PPTTELMYAWHLPDAIEAMVGVGRLDDAEILTAALERNGVEHDRR
TH_3931|M.thermoresistible__bu ILGPDLEGTEIITAGFLPDLVEAQVLMGLLDDAEPLVQALTRNGRRLDRP
MAB_3361|M.abscessus_ATCC_1997 -----EHEDLGLYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSD
MMAR_0085|M.marinum_M -----RYDDVGMCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTP
Mb0914c|M.bovis_AF2122/97 -------------GWHRMVALTIRARVATARGEPELARDDAHAALACGAE
Rv0890c|M.tuberculosis_H37Rv -------------GWHRMVALTIRARVATARGEPELARDDAHAALACGAE
MLBr_01753|M.leprae_Br4923 -------------GWHQMAALTTRARIAMAQGEPELARADIHAALACGAD
MSMEG_6828|M.smegmatis_MC2_155 -------LHRTSRRWAIADLAEAAAGAEKADIARPLLAEAEEQAERLGID
MUL_2555|M.ulcerans_Agy99 -APGEFPPLALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPP
MAV_0578|M.avium_104 ------------LARDRGQPTHELACIQAAAQWGDAAGAVRARALADALS
.
Mvan_1863|M.vanbaalenii_PYR-1 WMKAVGMRCRAMLL-AARGDVIAAEQTAHRAMAEHDRLPMPFERARTQLL
Mflv_4504|M.gilvum_PYR-GCK WMRAVGARCRAMLL-AAHGDVAAAEQMAHRAISEHDHLPMPFERARTRLL
TH_3931|M.thermoresistible__bu WMLAVAARCRAMML-AARGDLAGAVAAVX---XXGRRRSGPGAAARHR--
MAB_3361|M.abscessus_ATCC_1997 WSQGMVARSRALIT-VGH----DAEPHYREAIQRLTNTRISAHLARAHLI
MMAR_0085|M.marinum_M TALGIGASATALVS-DGS----IADAAYREAITHLRRSPVAVHLARTHLT
Mb0914c|M.bovis_AF2122/97 LHIYQGMPDAMELL-AGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIW
Rv0890c|M.tuberculosis_H37Rv LHIYQGMPDAMELL-AGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIW
MLBr_01753|M.leprae_Br4923 IQASLGISDSMELL-AELISQGDNHRQAGRLFGAASAQREKTGEVRFKVW
MSMEG_6828|M.smegmatis_MC2_155 SFLVHRAHALLADS-VAE-----SEDRFRAALGAAERTGAELESARTHLL
MUL_2555|M.ulcerans_Agy99 RLAIATGAAEALCA-SDE----RAPALFEKVLGHPAVASFPFEHARIRLA
MAV_0578|M.avium_104 LPLADAIACHAEALRAGNGEALLTVAAAYRAIGDAAAAADAAAQASAAFV
.
Mvan_1863|M.vanbaalenii_PYR-1 LGQLQRRLRQKNTAATNLNEALRTFEEMGTPLWVRRARAELARAVVAPAE
Mflv_4504|M.gilvum_PYR-GCK LGQLQRRLRQKATAAKNLTDALHTFEQLGTPLWAQRARSELARAVVAPAE
TH_3931|M.thermoresistible__bu -GAVRRRRRPDRRGAR-----------AGRPAGGTQPVGLLVRTVPR---
MAB_3361|M.abscessus_ATCC_1997 YGEWLRRCNRRSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRK
MMAR_0085|M.marinum_M YGEWLRRERRRSEARSQLRIAYDMFAQMGAAGFAERARRELSATGEAVYV
Mb0914c|M.bovis_AF2122/97 DAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPA
Rv0890c|M.tuberculosis_H37Rv DAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPA
MLBr_01753|M.leprae_Br4923 DAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPT
MSMEG_6828|M.smegmatis_MC2_155 YGVWLRRRRRIVDARVHLSAALTAFDRAGAVPFAERAAAELRAAGVTSAP
MUL_2555|M.ulcerans_Agy99 YGMRLRRLRRYRNARVVLRAAAEIFAGLGAEPWTQRARNELRAAGTAVRH
MAV_0578|M.avium_104 EGQQHQRGRYAAALAGELAEECG-----GLCTPALRTPAGLKLSG-----
. . .
Mvan_1863|M.vanbaalenii_PYR-1 GLS--------QLTPSEQRVAEMAASGATNKDIASAMFISAKTVEHNLTK
Mflv_4504|M.gilvum_PYR-GCK G-----------LTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTR
TH_3931|M.thermoresistible__bu ---------------RTARHGRIPAPGRXRGDRADRAPGSQR--------
MAB_3361|M.abscessus_ATCC_1997 RSASSE----KALTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRK
MMAR_0085|M.marinum_M QPTGIT----VDLTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSK
Mb0914c|M.bovis_AF2122/97 RGWG-------SLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQTHLTH
Rv0890c|M.tuberculosis_H37Rv RGWG-------SLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQTHLTH
MLBr_01753|M.leprae_Br4923 TGWE-------SLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVHTHLTR
MSMEG_6828|M.smegmatis_MC2_155 RPGTHSGADAGALTPQELQIAQMAAAGMTNREIADRIYLSHRTVAAHLYK
MUL_2555|M.ulcerans_Agy99 SAAVGP----APLTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYR
MAV_0578|M.avium_104 ---------------RQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYR
.: * : * * :
Mvan_1863|M.vanbaalenii_PYR-1 IYRKLGISSRAELGRRMDRAGEP----
Mflv_4504|M.gilvum_PYR-GCK IYRKLGISSRAELGRRMDQPGL-----
TH_3931|M.thermoresistible__bu -GGRAGPADRTR-GAVADAAGR-----
MAB_3361|M.abscessus_ATCC_1997 VFAKRGITSRRQLRSGR----------
MMAR_0085|M.marinum_M IFAKLGVTSRRELRAILMESP------
Mb0914c|M.bovis_AF2122/97 VYAKLGLASRVQLVDEAARRGSPS---
Rv0890c|M.tuberculosis_H37Rv VYAKLGLPSRVQLVDEAARRGSPS---
MLBr_01753|M.leprae_Br4923 IYSKLGLTSRVQLVQEAARHN------
MSMEG_6828|M.smegmatis_MC2_155 VFPKLGITRRNQLHAALGAPTGIA---
MUL_2555|M.ulcerans_Agy99 LFPKLGVTNRAGLHDALDAIHAAPDQI
MAV_0578|M.avium_104 ACQRVGAQSRDELATIIRSRPAGRES-
: * *