For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_3931 (-)

annotation: putative regulatory protein, LuxR
coordinates: 1903992 - 1906025
length: 678

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3931--100% (678)putative regulatory protein, LuxR
M. thermoresistible (build 8)TH_3225-2e-2127.73% (649) PUTATIVE regulatory protein, LuxR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0393-3e-0823.79% (412) LuxR/UHPA family transcriptional regulator
M. gilvum PYR-GCKMflv_1156-1e-11542.58% (620) regulatory protein, LuxR
M. tuberculosis H37RvRv0386-3e-0823.79% (412) LuxR/UHPA family transcriptional regulator
M. leprae Br4923MLBr_02341-3e-0727.86% (140) putative regulatory protein
M. abscessus ATCC 19977MAB_3361-7e-1325.00% (600) LuxR family transcriptional regulator
M. marinum MMMAR_1324-2e-1324.51% (710) hypothetical protein MMAR_1324
M. avium 104-----
M. smegmatis MC2 155MSMEG_3290-2e-2128.99% (583) regulatory protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_5653-1e-11242.78% (582) regulatory protein, LuxR

CLUSTAL 2.0.9 multiple sequence alignment


Mb0393|M.bovis_AF2122/97            MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv         MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Mflv_1156|M.gilvum_PYR-GCK          ------------------------------MKAVDDFLAGLQQLQPAGLL
Mvan_5653|M.vanbaalenii_PYR-1       ---------------MMSGVGGGYGLTAASAAAVDDFLESARR-HPAGML
TH_3931|M.thermoresistible__bu      --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997      -------------------------------------------------M
MSMEG_3290|M.smegmatis_MC2_155      -------MVQVSGVSRDDGPVAGLIGRRDECAVLDQLVDAVAGGASRALM
MMAR_1324|M.marinum_M               ----------------MDLGGCRLIERVDELAALESFVN--GGTADGCLA
MLBr_02341|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
Rv0386|M.tuberculosis_H37Rv         GVRPVEQGEGDSFVLAFACASDAVAAALDLQRARLAPIRLRIGVHTGEVA
Mflv_1156|M.gilvum_PYR-GCK          IEGEAGIGKTTMLAGVVDAARQAGFRVLSAHGDQSGSGLAHAAIADLFAG
Mvan_5653|M.vanbaalenii_PYR-1       IEGDAGIGKTTMWNTVVQRAAEAGFVVLTARAGQAESGLAHAAVADLLSA
TH_3931|M.thermoresistible__bu      --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997      LRGQAGVGKTALLR--YVLGKASGQLIAQASGIQSEMELAFAGLQQFCAP
MSMEG_3290|M.smegmatis_MC2_155      IRGEAGVGKTALLD--YAAARAAELQIARIVGIQSEMELAFAGIHQLCLP
MMAR_1324|M.marinum_M               LRGDSGVGKSMLVQALSERAAVPGRRVLRCSGVEAEAAFVLAGLSQLVYP
MLBr_02341|M.leprae_Br4923          -----------MTTALVCVACGAELRSIAKFCDECGSPVVEAETPAEYKQ
                                                                                      

Mb0393|M.bovis_AF2122/97            LRDEGNYAGPTINRTARLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDL
Rv0386|M.tuberculosis_H37Rv         LRDEGNYAGPTINRTARLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDL
Mflv_1156|M.gilvum_PYR-GCK          VQTDILDGLPELQRRAADGVLRRG---DGTGGPTDERVIAAALLGAVHGS
Mvan_5653|M.vanbaalenii_PYR-1       VDPEIVDALPDMQRLAAGRVQLRD---HAGGRPADERATAAALLSAVHAA
TH_3931|M.thermoresistible__bu      --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997      LTKYSG-AIPDPQREALTIAFG-----TRSGPPPDRFLIGLAVLSLLAAA
MSMEG_3290|M.smegmatis_MC2_155      LLPRLG-HLPVPQRDALEVALG-----MATGSSPDRFLVGLAVLNLLADA
MMAR_1324|M.marinum_M               LREFIAQLGADDQR-TLAAVLG-----AVPDRVPTVTALTFALLNLLALA
MLBr_02341|M.leprae_Br4923          VT---------------------------------VLFADVVGSMDIAAA
                                                                                      

Mb0393|M.bovis_AF2122/97            GTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGR
Rv0386|M.tuberculosis_H37Rv         GTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGR
Mflv_1156|M.gilvum_PYR-GCK          ATRTPVLVAVDDVQWLDPSSVAVLAFVARRVKG-RVGFVVAERP----GV
Mvan_5653|M.vanbaalenii_PYR-1       GARAPVLIAIDDVQWLDASSRAVLAFAARRLKG-AVGVVATERT----GQ
TH_3931|M.thermoresistible__bu      --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997      AEHQPVLCVIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRD----GT
MSMEG_3290|M.smegmatis_MC2_155      AADRPLLCLVDDEQWLDRSSAQVLAFVARRLGSESVGMIFAARE----PS
MMAR_1324|M.marinum_M               SEVTPLLVVIDDAHWFDDVSARVIAMAGRRLDGAAVRFLAACRN------
MLBr_02341|M.leprae_Br4923          VGLERLREIMTELVSRAAGVIERYGGTVDKFTGDGIMAIFGAPT------
                                                                                      

Mb0393|M.bovis_AF2122/97            GAQITEVHRLVTDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGRAWFVDL
Rv0386|M.tuberculosis_H37Rv         GAQITEVHRLVTDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGRAWFVDL
Mflv_1156|M.gilvum_PYR-GCK          GPGLPAATWLQVGTGALTRLPVAPMSLGALHTMLSSRLGRRFSRPQIVRI
Mvan_5653|M.vanbaalenii_PYR-1       QSQERAASWLQVGTGGLARVQVAPMSLGALHSMLSDRLGRRFSRPAIVRI
TH_3931|M.thermoresistible__bu      --------------------------------VLLARLGRTFPRAVMVQI
MAB_3361|M.abscessus_ATCC_1997      DS----------ELAGLPELTVHGLRAADAGTLLDSVIPGLLDERVRDRI
MSMEG_3290|M.smegmatis_MC2_155      D-----------AAAGVPALVVRGLRGADARALLDSALSAPLDPRVRDQI
MMAR_1324|M.marinum_M               ------EVPNALADGGWPQMVLAPLGPEQAERFLD-QLDVDLPHSARVGV
MLBr_02341|M.leprae_Br4923          -----------ALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRV
                                                                     *   :           :

Mb0393|M.bovis_AF2122/97            APITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHL
Rv0386|M.tuberculosis_H37Rv         APITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHL
Mflv_1156|M.gilvum_PYR-GCK          AEVSGGNPLYALELARVADGAGSRPGQRLP------ESLSELVRLRVDGL
Mvan_5653|M.vanbaalenii_PYR-1       AEASGGNPLYALELARVMDGDMLRPGVRLP------STLAEVVGLRVDKL
TH_3931|M.thermoresistible__bu      HHISGGNPFYALELARAMDDG--SPLVRLP------SSLTELVRARIGRI
MAB_3361|M.abscessus_ATCC_1997      VAETQGNPLALLELPRDMTAEELAGGFGWPDGGRLAGQIEQTFLRRVQQL
MSMEG_3290|M.smegmatis_MC2_155      LAETDGNPLALLELPRTLTRDALAGVFGLPGGSGVAADIEHAFGVRIGEL
MMAR_1324|M.marinum_M               LEQAAGNPLALAELSRCALENSWAPDAPLP----LTQRLVAIFGDRLNKL
MLBr_02341|M.leprae_Br4923          GLNS-GQVIVGEIGSSALGYTAVGVQVGMA------QRMESVAPPGVVML
                                       :  : .                    .                   :

Mb0393|M.bovis_AF2122/97            LDATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSDEAVEM
Rv0386|M.tuberculosis_H37Rv         LDATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSDEAVEM
Mflv_1156|M.gilvum_PYR-GCK          AEDVRDVLLVAASAT-----SPTVDLLAKAVGVTPAAVTGLVEAAEVEGI
Mvan_5653|M.vanbaalenii_PYR-1       DDDVRDVLLVAASVT-----QPTVDLLAQTLAVRAEQVTALLESAEVEGV
TH_3931|M.thermoresistible__bu      GADARNVLLAAACSA-----APTVESVARAVGVDEPRVVRLLSDAVDRDI
MAB_3361|M.abscessus_ATCC_1997      PAHTQTLLLAAATDP-----LGDVTLLARAAQQLG--IPMHAIAPAEAAD
MSMEG_3290|M.smegmatis_MC2_155      PEPTRDLLLIAAAEP-----TGDAPLVWRAAARLG--IGSDAAAPAVEAE
MMAR_1324|M.marinum_M               DESVKAQLLRGALDG-------AATGGVASAPPRTRYVMQGVDAAIEHGV
MLBr_02341|M.leprae_Br4923          SESTARLVEQTAVLG------APQTVRIKGAEDAVPARRLLRVAEPRQPT
                                       .   :   .                                      

Mb0393|M.bovis_AF2122/97            FCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELAAARLRSMTLDE
Rv0386|M.tuberculosis_H37Rv         FCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELAAARLRSMTLDE
Mflv_1156|M.gilvum_PYR-GCK          VVIDGNRIRFTHPVLAN-------------GIYAGADPQRRREVHRRLAD
Mvan_5653|M.vanbaalenii_PYR-1       IAIEGNRVRFTHPLLAS-------------GIYDSAAPARRREFHRRLAD
TH_3931|M.thermoresistible__bu      IRMDGHRICFSHPLLAR-------------GVYDDATATRRRAMHRRLAE
MAB_3361|M.abscessus_ATCC_1997      LVELSTRVRFRHPLVRS-------------AVYISANPLERRRIHGVLAG
MSMEG_3290|M.smegmatis_MC2_155      LASFDTRVTFQHPLVRS-------------VVYRAAALDDRRRAHRALAA
MMAR_1324|M.marinum_M               LVVDRGELVFRHPLVRA-------------AVIQTSTAGQRRHAYAQLAD
MLBr_02341|M.leprae_Br4923          WFSESTLVGREWELATL-----------------AAMLDRSIGGRGSVVG
                                           :     :                                 :  

Mb0393|M.bovis_AF2122/97            IIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAV
Rv0386|M.tuberculosis_H37Rv         IIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAV
Mflv_1156|M.gilvum_PYR-GCK          LKT-----------------------------------DPELRARHLALA
Mvan_5653|M.vanbaalenii_PYR-1       IQT-----------------------------------QPELRARHLALA
TH_3931|M.thermoresistible__bu      IVD-----------------------------------EPELQARHLAIA
MAB_3361|M.abscessus_ATCC_1997      ATDPG--------------------------------ADPDRRAWHRAHA
MSMEG_3290|M.smegmatis_MC2_155      ATDAE--------------------------------VDPDRRAWHLAHA
MMAR_1324|M.marinum_M               LYP----------------------------------DDVVRRAAYLAHA
MLBr_02341|M.leprae_Br4923          LVG----------------------------------PAGIGKTRLVAEA
                                                                                     .

Mb0393|M.bovis_AF2122/97            FVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLVMADDNSGRTCYRL
Rv0386|M.tuberculosis_H37Rv         FVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLVMADDNSGRTCYRL
Mflv_1156|M.gilvum_PYR-GCK          STVADETTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVSR---RI
Mvan_5653|M.vanbaalenii_PYR-1       ATVADDATLATLDAAADSARARGAPAAAAELVELAIRLGGDRVSR---RI
TH_3931|M.thermoresistible__bu      VGWADPQVLACLDRAAEAARLRGAPSTAAELIDMAIGLGGDSPER---RL
MAB_3361|M.abscessus_ATCC_1997      AAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPAARGRRAL
MSMEG_3290|M.smegmatis_MC2_155      AAGPDAAAAAELESSAARARSRGGACAAAAFLERATALTVDPVLRNDRAL
MMAR_1324|M.marinum_M               TVDPDPAVVDTLAAAAELTIRRGDACQAIELLRRAGELSDRPRRREQLLA
MLBr_02341|M.leprae_Br4923          VQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAVAQISGLDDRSARARV
                                                   .              ::     :            

Mb0393|M.bovis_AF2122/97            CETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPSDYSHCLD-
Rv0386|M.tuberculosis_H37Rv         CETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPSDYSHCLD-
Mflv_1156|M.gilvum_PYR-GCK          RAAEHHVVAGDMRRAATLLEQALVDLRPGVLCAIALNLLAGVRMVEDDY-
Mvan_5653|M.vanbaalenii_PYR-1       RAAEHHYVAGDMPRAAELLDQVTGDLRPGVLRAIALNLRAGVRIFEDDY-
TH_3931|M.thermoresistible__bu      MSARNHVDAGDGDSARAILKRSSAEMT-GAPRAQVLRLLGGLEILYGSY-
MAB_3361|M.abscessus_ATCC_1997      AAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAESRVG
MSMEG_3290|M.smegmatis_MC2_155      AAAAAKAEAGAFESAQDLLAMVEATSLSDLQQAQVDVLRARLAFVTSHG-
MMAR_1324|M.marinum_M               SAAFVALQAAQLDEAERLLADAGLGGGASASALLISSFISLYRYGDVTA-
MLBr_02341|M.leprae_Br4923          REQIPDADTQDLLLLDDLLGIADPAVELPRLDPDARRRRLTALINVAQL-
                                                     :                                

Mb0393|M.bovis_AF2122/97            ----QAETEIDNLRAAFVWNRENSDTEGALALASSLLRVWMTRGRIQEGR
Rv0386|M.tuberculosis_H37Rv         ----QAETEIDNLRAAFVWNRENSDTEGALALASSLLRVWMTRGRIQEGR
Mflv_1156|M.gilvum_PYR-GCK          -------IRAVELLERARAD-ADNDAVLVTTLLSLGFCLGMTGSFTAQLA
Mvan_5653|M.vanbaalenii_PYR-1       -------AGAVVLLERACADAADNDEVRVSSLVALAFAQGMVGAFEDQFA
TH_3931|M.thermoresistible__bu      -------LDAADALRRALTDATDDAVLRARILTLLAFVEFNTGRRAAAAA
MAB_3361|M.abscessus_ATCC_1997      AFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRG
MSMEG_3290|M.smegmatis_MC2_155      -------SDAPPLLLKAARRLGGIDPDRARAVYLDAMLAAMFAGRLATGA
MMAR_1324|M.marinum_M               ---------THRRLVERLQSADDLDGETLTRMVNLLLAVSMFAADPALWQ
MLBr_02341|M.leprae_Br4923          ---------ALSRPAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVT
                                                                        .             

Mb0393|M.bovis_AF2122/97            AWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAAGMEQAQQALV
Rv0386|M.tuberculosis_H37Rv         AWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAAGMEQAQQALV
Mflv_1156|M.gilvum_PYR-GCK          TVREAVAVAERAGV---PALTSRALAMWVHVSFQAGNGLDSAALLRAVDL
Mvan_5653|M.vanbaalenii_PYR-1       SALRAVAVAERAGV---PALTSQALTTWVYVRLQAGGGLDGPALRRAVEL
TH_3931|M.thermoresistible__bu      DADEAVECATRAGD---RGVLSQALAMRTLVTCLLGRGFDPAALHRALEL
MAB_3361|M.abscessus_ATCC_1997      GAVEVAEPARLAPAGAQPARPSDLLLDGLARRITHGAAASAQTLGEALTL
MSMEG_3290|M.smegmatis_MC2_155      NLVEVAAAARSAPERSGAAEVSDLLLDWLTAHYGRGYVAARSALGDVLSA
MMAR_1324|M.marinum_M               ITDGLVDSLADRLG--------ELSVIYRDAWADAARRGRTVTQRLKEQL
MLBr_02341|M.leprae_Br4923          YRPEYHGALRHVVG------------AQIIAVAPLSDVETSTLVAELLGL
                                                                                      

Mb0393|M.bovis_AF2122/97            IAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWR
Rv0386|M.tuberculosis_H37Rv         IAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWR
Mflv_1156|M.gilvum_PYR-GCK          EDPEDNTPIPFRASAARG-LSLALTGRLAEADGQLAAVAQRSAQRGAEQD
Mvan_5653|M.vanbaalenii_PYR-1       EGADGDTPIPFRASAMQG-LALAVTGQLEDADRQLAEIAQRCLHRGAEHD
TH_3931|M.thermoresistible__bu      EEPGSGDLGITRTSGLHA-MLLAYTGRFDAAVEVMRAVARHCRDRGEGLD
MAB_3361|M.abscessus_ATCC_1997      IRCEADRPANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVG
MSMEG_3290|M.smegmatis_MC2_155      FDGEADDLP-LNRMLLAS-----TAAHYAWDDVRLDVFTAHHVERARATG
MMAR_1324|M.marinum_M               DRLAELEPWDVMRVALAG----YYVDLIDDFRSVLVPLADREIEGGAATI
MLBr_02341|M.leprae_Br4923          DQSVTQIGELITERAAGN---PFFAQEITRELAERGVLTGERGRYACSTD
                                                            .                         

Mb0393|M.bovis_AF2122/97            LAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCLGY
Rv0386|M.tuberculosis_H37Rv         LAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCLGY
Mflv_1156|M.gilvum_PYR-GCK          VMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMV---------I
Mvan_5653|M.vanbaalenii_PYR-1       LMAVTGYRTLIAIWRGRFDDAGRLAADLLERARQVGGSMA---------L
TH_3931|M.thermoresistible__bu      LTYIALHRVLVELWRGEVRAAATIAEEAIESAAVLDGDLPR-------GV
MAB_3361|M.abscessus_ATCC_1997      ALSLLPAALIYRAGMHVHAGELDAAAELVQEADAISAATGH-------AP
MSMEG_3290|M.smegmatis_MC2_155      ALSEVPIALNSRAIALLFFGDLDGAADAVDEIQAADDATGA-------LL
MMAR_1324|M.marinum_M               ALATLALVTAYQLASGQWAEAVDTSQRGVALCSQHHYELFG-------YQ
MLBr_02341|M.leprae_Br4923          VAEVCVPATLQATIAARIDRLSPPAKQLLVAAAVIGFRFGS---------
                                                            :                         

Mb0393|M.bovis_AF2122/97            AQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSA
Rv0386|M.tuberculosis_H37Rv         AQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSA
Mflv_1156|M.gilvum_PYR-GCK          AFSICAAVAAYRGREDQAR--DQAAGALAQGGDYVALTVWASATLAFLEV
Mvan_5653|M.vanbaalenii_PYR-1       AMSICAAAAAYRGEETQAR--EFARQALEQGAGHVPLTAWARATLAFLEV
TH_3931|M.thermoresistible__bu      VLLLRQALATYAGRVDDARGDGARAAAIFARSGSAILTTLTTSLTGFLEL
MAB_3361|M.abscessus_ATCC_1997      IRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNN
MSMEG_3290|M.smegmatis_MC2_155      APYAEVGLAAMRGDLARTASLVDATVAAVTARGEGNGLTVAWWAEAVLHN
MMAR_1324|M.marinum_M               LRGYLGVISACRGDVVRARELAAQVRVWAEPRRVGFLTGAVAQIAILCSF
MLBr_02341|M.leprae_Br4923          DLLASLGIDLSVDELIDANLVDQVRFTAPVEYAFRHPLIRTVAYESQLKS
                                                     .                                

Mb0393|M.bovis_AF2122/97            ARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNL
Rv0386|M.tuberculosis_H37Rv         ARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNL
Mflv_1156|M.gilvum_PYR-GCK          SRGNYEQALEAAEP-------------LVDLYR-DFPGTELMSACFMPDA
Mvan_5653|M.vanbaalenii_PYR-1       SLGEHHRAVEAAEP-------------LMALYR-PFSGTEVITGSFLPDA
TH_3931|M.thermoresistible__bu      SVGDHVAAIATLRP-------------LLPILGPDLEGTEIITAGFLPDL
MAB_3361|M.abscessus_ATCC_1997      SLGRYELAFMAAR------------------RACEH-EDLGLYSWCLIEL
MSMEG_3290|M.smegmatis_MC2_155      GFGSARKALEAAS------------------RAAAFPPELASANWALIEL
MMAR_1324|M.marinum_M               AEGDYESAYLQATAIT---------------APGEFPPFALHATRTLFDL
MLBr_02341|M.leprae_Br4923          DRARLHRRLAAAIE-----------------------------ARAPHSV
                                      .                                             . 

Mb0393|M.bovis_AF2122/97            SLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALAT
Rv0386|M.tuberculosis_H37Rv         SLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALAT
Mflv_1156|M.gilvum_PYR-GCK          IESLIAVGRLDEAEPLIAAFERNGAELDRPWQ-----------LAIGNRC
Mvan_5653|M.vanbaalenii_PYR-1       AEALIALGRHDDAEQMVGALERNGAALDRPWM-----------LAVGNRC
TH_3931|M.thermoresistible__bu      VEAQVLMGLLDDAEPLVQALTRNGRRLDRPWM-----------LAVAARC
MAB_3361|M.abscessus_ATCC_1997      IEAAVRCGEHDTAVKAFGQLEERALAAQSDWS-----------QGMVARS
MSMEG_3290|M.smegmatis_MC2_155      VEAATRCGAVETAAEAAADLAELTTSSGTDWA-----------LGLAARA
MMAR_1324|M.marinum_M               VEAAVHTDRLNEARRHVRAAKRLQFADAPPRL------------AIATGA
MLBr_02341|M.leprae_Br4923          DQHAVLIAEHLEAAGDLHAAYGWHMR------------------AAAWAT
                                                *                               .     

Mb0393|M.bovis_AF2122/97            RARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGLASDAGT
Rv0386|M.tuberculosis_H37Rv         RARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGLASDAGT
Mflv_1156|M.gilvum_PYR-GCK          RAMLLSATGDLDGALAAAERAMAEHARLPMPFERARSALTLGEVLRRLRR
Mvan_5653|M.vanbaalenii_PYR-1       RALLLVAQGDLDGALGAVERAMAEHDRLPMPFERARTQLVMGEVLRRLRR
TH_3931|M.thermoresistible__bu      RAMMLAARGDLAGAVAAVX---XXGRRRSGPGAAAR----HRGAVRRRRR
MAB_3361|M.abscessus_ATCC_1997      RALITVGHDAEPHYREAIQRLTNTRIS----AHLARAHLIYGEWLRRCNR
MSMEG_3290|M.smegmatis_MC2_155      RALVSGPAESERWYLESIERLENTRAR----AELARSRLVYGEWLRRERR
MMAR_1324|M.marinum_M               AEALCASDERAP---ALFEKVLGHPAVASFPFEHARIRLAYGMRLRRLRR
MLBr_02341|M.leprae_Br4923          NQDVRAARVSWEHATKIADALTAEDPHRAAMCIAPRTRLCGIAWRGRFNS
                                       :                              .               

Mb0393|M.bovis_AF2122/97            HHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEKDFAAAW
Rv0386|M.tuberculosis_H37Rv         HHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEKDFDAAW
Mflv_1156|M.gilvum_PYR-GCK          RDAAA-AVRDALAQFEELGVPLWVARARIALSGLAV--------------
Mvan_5653|M.vanbaalenii_PYR-1       RDAAEQIVREALRQFDGLGSPVWADRARKILARVNG--------------
TH_3931|M.thermoresistible__bu      PDRRG-------------------ARAGRPAGGTQP--------------
MAB_3361|M.abscessus_ATCC_1997      RSDARTELTAAHGSFVNMGTAAFAERAERELRATGAKVRK----------
MSMEG_3290|M.smegmatis_MC2_155      RTAARSELRTAHEMFSAMGMSAFAARAQRELAAAGDRIRET---------
MMAR_1324|M.marinum_M               YRNARVVLRAAAEIFAGLGAEPWTQRARNELRAAGTAVR-----------
MLBr_02341|M.leprae_Br4923          S-------------------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            AEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVGEGLANK
Rv0386|M.tuberculosis_H37Rv         AEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVGEGLANK
Mflv_1156|M.gilvum_PYR-GCK          -----------------------SGSAVGSELTDSERRIAELAASGMSNR
Mvan_5653|M.vanbaalenii_PYR-1       -----------------------SGRSGSVVLTDSELRIAEHVASGMSNK
TH_3931|M.thermoresistible__bu      -----------------------VGLLVRTVPRRT-ARHGRIPAPGRXRG
MAB_3361|M.abscessus_ATCC_1997      -----------------------RSASSEKALTAQEAQIARMAGQGLTNQ
MSMEG_3290|M.smegmatis_MC2_155      -----------------------VIAAVDHRLTAQEAHIARLARDGLSNP
MMAR_1324|M.marinum_M               ----------------------HSAAVGPAPLTAQERLVAELAAKGLSNK
MLBr_02341|M.leprae_Br4923          ---------------------------------------SGFDEVRQLCN
                                                                                      

Mb0393|M.bovis_AF2122/97            DIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT------
Rv0386|M.tuberculosis_H37Rv         DIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT------
Mflv_1156|M.gilvum_PYR-GCK          DVAETLFVSVKTIETNLSRVYRKLGIRSRAQLGRMLR---------
Mvan_5653|M.vanbaalenii_PYR-1       EVADALYVSVKTVETNLTRVYRKLGIRSRAQLGTQLAQLREA----
TH_3931|M.thermoresistible__bu      DRADRAPGSQRGGRAGPADRTRGAVADAAGR---------------
MAB_3361|M.abscessus_ATCC_1997      EIAAQLFISSHTVEWHLRKVFAKRGITSRRQLR------SGR----
MSMEG_3290|M.smegmatis_MC2_155      EIGARLFISARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR----
MMAR_1324|M.marinum_M               EIAARLCLSPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI
MLBr_02341|M.leprae_Br4923          ATGDKAPLAVATVGPAIDHVYQDRLH--------------------
                                      .     :