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MLLGRESEQQRIAELVAGARLGQSGVLVVRGEAGIGKTALLEDTAAHLGDMTLVRASGTEAESTLEFSGL HQLLRPALHLIDRLPAPQCDALAVALLMRDGPAPERFAVGAATLSLLSRYAEDSALLVLVDDAHLLDSPS ADALTFVARRLLADPIAMVISTRPEPHAAFTATDLPVLDLGGLDLAAASELISRSAPNPTTAEDAEHLHR VTLGSPLALVELSRDIERVRDSPPVLPVPVSDAVAQAFGRRITALPDSTRLALLLAVVADGDLGLASRAA AEMGTSLAPIVEAESIELMRINAGRVDFRHPLVRSAVYAAADAQTRRDVHRAVAAAMPAAAHTRRVWHLS EAVVGPDDAVADDLVDLAEKATARGAHGVAANALTRSAELTNDDVLRCARLIRAGEAAWFAGHLTRARGL IDDAEAIAAGPDTLTQISALRGHIALRSGSLRDAHDLLVDAAARTDAAEADATVGLLADAVTACFYMCDT AAGLALADRIEVLLPACRTGSARTRGQLAIGVARVIAGGDGMRWLRIAVETLNNEPSVLDDPRRPDWSIV GALFLRETAAGRDLMQRVVQDRRKRTAIGALPNLLFHTARDDATTDNWQSALASYTESVALARETSQSTD LAASLAGLAWLQARMGRFAECRVNAAEARQLARRHHITFAHLWAQFALGDSALAEGNAGEAIVHYQGMES LLTDNRFRDVDLAPGPELAEAHMRHGDAAAAHEVAVGYLGRAQEKSQPWALARAHRAMALTAGEPGVCEA HFSEALRLHELNPDRFEAARTRLAFGSSLRRIKKRVAARPHLRAALEDFERLGARPWADAAADELEATGE RARRGGTEYSALLTSQELRIAQMLGRGATTKEAAAALFLSPKTVEYHLRNVYHKLAISSRSELKAVVQDR ADG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3871 | - | - | 100% (913) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_5002 | - | e-102 | 34.15% (937) | regulatory protein, LuxR |
| M. vanbaalenii PYR-1 | Mvan_1214 | - | 9e-93 | 31.30% (949) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 3e-13 | 27.13% (527) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4504 | - | 3e-59 | 28.91% (941) | regulatory protein, LuxR |
| M. tuberculosis H37Rv | Rv0386 | - | 5e-13 | 27.03% (529) | LuxR/UHPA family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 2e-10 | 23.74% (438) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 3e-90 | 31.60% (921) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 3e-95 | 31.97% (926) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 2e-16 | 24.71% (963) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0321 | - | 1e-103 | 33.40% (937) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3225 | - | 2e-94 | 32.56% (943) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 1e-22 | 27.07% (569) | hypothetical protein MUL_2555 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0393|M.bovis_AF2122/97 MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
Rv0386|M.tuberculosis_H37Rv MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHD
MSMEG_0321|M.smegmatis_MC2_155 ------------------METGGRGQPLHGRAAECDALRRSIADVQSAQS
TH_3225|M.thermoresistible__bu ------------------MSSRDGDVVLHGRAAEIATLRDVMSTARAGSS
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0085|M.marinum_M ----------------------MPTVTLVGRHREQQQLQQLLDAARRGES
Mvan_3871|M.vanbaalenii_PYR-1 --------------------------MLLGRESEQQRIAELVAGARLGQS
Mflv_4504|M.gilvum_PYR-GCK ------------MRAALPAAMMNAMSDASPQAADDPQVAGFLCTATSAPT
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ---------------------MIGGELLIGRDSELAAIRRALN--GADHH
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 GVRPVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGE
Rv0386|M.tuberculosis_H37Rv GVRPVEQGEGDSFVLAFACASDAVAAA--LDLQRARLAPIRLRIGVHTGE
MSMEG_0321|M.smegmatis_MC2_155 RVLVLRGEAG---VGKTALLDFAAQHA--KGFRITQVAGVESDM-----E
TH_3225|M.thermoresistible__bu RVLVLHGEAG---VGKTALLGQLLGDA--AGMRCVQVAGVESDM-----E
MAB_3361|M.abscessus_ATCC_1997 ---MLRGQAG---VGKTALLRYVLGKA--SGQLIAQASGIQSEM-----E
MMAR_0085|M.marinum_M GVLVLRGDAG---IGKTTLLTDLVDNA--PDLRVLRVRGAEMEM-----E
Mvan_3871|M.vanbaalenii_PYR-1 GVLVVRGEAG---IGKTALLEDTAAHL--GDMTLVRASGTEAES-----T
Mflv_4504|M.gilvum_PYR-GCK G-LIIEGDAG---IGKTTLWLSLLQTARMRGFQVLTARVGQAES-----V
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 RGVVIAGAAG---VGKTWLARAALRRAGASGEQIKWIVGTQSAQ-----A
MLBr_02341|M.leprae_Br4923 ----------------------------MTTALVCVACGAELRS------
Mb0393|M.bovis_AF2122/97 VALRDEGNYAGPTINR-TARLRDLAHGGQTVLSGVT--ESLVIDRLPDKA
Rv0386|M.tuberculosis_H37Rv VALRDEGNYAGPTINR-TARLRDLAHGGQTVLSGVT--ESLVIDRLPDKA
MSMEG_0321|M.smegmatis_MC2_155 LAYAGLQQLCAPLMNN-LDDLPEPQRDALAVAFGLG--VGQTPDRFLVGL
TH_3225|M.thermoresistible__bu LAYAGLHQLCAPLLDR-LDDLPSPQRDVLNVAFGRG--AGPAPGRFLVGL
MAB_3361|M.abscessus_ATCC_1997 LAFAGLQQFCAPLTKY-SGAIPDPQREALTIAFGTR--SGPPPDRFLIGL
MMAR_0085|M.marinum_M LTYSGVQQLCGPLMSL-IGQLPEPQLDALEIALGRK--RGRAPDRLLLGL
Mvan_3871|M.vanbaalenii_PYR-1 LEFSGLHQLLRPALHL-IDRLPAPQCDALAVALLMR--DGPAPERFAVGA
Mflv_4504|M.gilvum_PYR-GCK MAFAALADLLGAVSDEHFAALPPLQRLALDRVLLRAGADGPATDQRVVAA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LPLGAFIGLLGDAMSEPLTSVRRVIETFVARQRRGR--------------
MLBr_02341|M.leprae_Br4923 --IAKFCDECGSPVVEAETPAEYKQVTVLFADVVGS--------------
Mb0393|M.bovis_AF2122/97 WLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLT
Rv0386|M.tuberculosis_H37Rv WLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLT
MSMEG_0321|M.smegmatis_MC2_155 AVLSLMAAAADEKP-----------------LLCIVDDAQWLDSVSVQTL
TH_3225|M.thermoresistible__bu AVLNLLAAAGADQP-----------------LLCVIDDAQWLDRVSLQTL
MAB_3361|M.abscessus_ATCC_1997 AVLSLLAAAAEHQP-----------------VLCVIDDAQWLDRVSLQTL
MMAR_0085|M.marinum_M AVLTLVGEASRASP-----------------ILCVVDDAQWVDSASVQAL
Mvan_3871|M.vanbaalenii_PYR-1 ATLSLLSRYAEDSA-----------------LLVLVDDAHLLDSPSADAL
Mflv_4504|M.gilvum_PYR-GCK GFVSLLHILAADAP-----------------VLIAIDDVQWLDASSRTAI
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 -------------------------------VVVGVDDAHLLDGLSALVV
MLBr_02341|M.leprae_Br4923 ---------------------------------MDIAAAVGLERLREIMT
Mb0393|M.bovis_AF2122/97 RFVGRGAQITEVHRLVTDNRLVTLTGAGG---------VGKTRLAAQLAA
Rv0386|M.tuberculosis_H37Rv RFVGRGAQITEVHRLVTDNRLVTLTGAGG---------VGKTRLAAQLAA
MSMEG_0321|M.smegmatis_MC2_155 AFVAR-RLLAEPVGLIFAVRDHGAPALAG---------LPELLVDGLSDT
TH_3225|M.thermoresistible__bu GFVAR-RLMAEPVAMVFALRDDIHEALVG---------VPALAVPGLADA
MAB_3361|M.abscessus_ATCC_1997 AFVTR-RLGSEPVAMLFAVRDGTDSELAG---------LPELTVHGLRAA
MMAR_0085|M.marinum_M AFVAR-RIHVDPVAMVFATRDRGPDALTG---------HCELSLQGLEDH
Mvan_3871|M.vanbaalenii_PYR-1 TFVAR-RLLADPIAMVISTRPEPHAAFTATD-------LPVLDLGGLDLA
Mflv_4504|M.gilvum_PYR-GCK EFAVR-RLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPPMDAG
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 HQLAQSGGVRLVVTVRTGSHQPDAVTALWKD-----DLLTRLDLEPLSAA
MLBr_02341|M.leprae_Br4923 ELVSRAAGVIERYGGTVDKFTGDGIMAIFG------------APTALEDH
Mb0393|M.bovis_AF2122/97 QIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLG
Rv0386|M.tuberculosis_H37Rv QIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDTVLRFLG
MSMEG_0321|M.smegmatis_MC2_155 DARELLDSVILGRLDERVRDRVVAETRGIPLALLEVPR------------
TH_3225|M.thermoresistible__bu DARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPR------------
MAB_3361|M.abscessus_ATCC_1997 DAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPR------------
MMAR_0085|M.marinum_M DARLVLSTAIPGRLNDSVAETVLAEANGNPLALLELHN------------
Mvan_3871|M.vanbaalenii_PYR-1 AASELISRSAPNPTTAEDAEHLHRVTLGSPLALVELSR------------
Mflv_4504|M.gilvum_PYR-GCK RLHALISHRLGRTLTRPVVLRIAEMSGGNPFYALELAH------------
MUL_2555|M.ulcerans_Agy99 ----------MPALSANLVASIDRHPERITLRCDDLQS------------
MAV_0578|M.avium_104 ATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLS------------
MLBr_02341|M.leprae_Br4923 ALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNS------------
.
Mb0393|M.bovis_AF2122/97 GRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSY
Rv0386|M.tuberculosis_H37Rv GRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSY
MSMEG_0321|M.smegmatis_MC2_155 ---------------------TIPAAELAGGFSTIAGRRSAGRVEDSFTS
TH_3225|M.thermoresistible__bu ---------------------TYAVGELAGGFVSPGAGSAPSRIEENYVH
MAB_3361|M.abscessus_ATCC_1997 ---------------------DMTAEELAGGFGWPDGGRLAGQIEQTFLR
MMAR_0085|M.marinum_M ---------------------ALIRGELAGGYGLANATRTETQIERTFVS
Mvan_3871|M.vanbaalenii_PYR-1 ------------------------DIERVRDSPPVLPVPVSDAVAQAFGR
Mflv_4504|M.gilvum_PYR-GCK ------------------------THVNSGDSPPAAEPPLPATLADVVRR
MUL_2555|M.ulcerans_Agy99 ---------------------------VFAELGAGPGDRVAALPGDRTRR
MAV_0578|M.avium_104 -----------------DQMAAGRMRRVAGVWMWDGDVAVSASLSDTVGR
MLBr_02341|M.leprae_Br4923 ------------------------GQVIVGEIGSSALGYTAVGVQVGMAQ
Mb0393|M.bovis_AF2122/97 RVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAI
Rv0386|M.tuberculosis_H37Rv RVPSLSLSDEAVEMFCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAI
MSMEG_0321|M.smegmatis_MC2_155 RVRSLPDEARQLLLLAAAEPIGDAALFVR----------AAAHLGVAVPA
TH_3225|M.thermoresistible__bu RIRALPAQTRRLLLIAAAEPIGDSALFLR----------AAALMGIAVDA
MAB_3361|M.abscessus_ATCC_1997 RVQQLPAHTQTLLLAAATDPLGDVTLLAR----------AAQQLGIPMHA
MMAR_0085|M.marinum_M RLRALPSETKTFLLVAAAESTARPEWLWA----------AAHRLGIGPEA
Mvan_3871|M.vanbaalenii_PYR-1 RITALPDSTRLALLLAVVADG-DLGLASR----------AAAEMGTSLAP
Mflv_4504|M.gilvum_PYR-GCK RVGLLDDATRTLLLGVACVADPTVELLAR---------AHGASTDEITAG
MUL_2555|M.ulcerans_Agy99 RVCGPACELSGGRFRPSARPQSCPGLTEA------------ASPGRSRGP
MAV_0578|M.avium_104 QLGRLTPPLALVVDTLSQCEPLPVDLLCD-----------LASREDLVAA
MLBr_02341|M.leprae_Br4923 RMESVAPPGVVMLSESTARLVEQTAVLGAP---------QTVRIKGAEDA
::
Mb0393|M.bovis_AF2122/97 ELAAARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTL
Rv0386|M.tuberculosis_H37Rv ELAAARLRSMTLDEIIDGLRDRFALLTGGARTAAHRQQTLWASVDWSYTL
MSMEG_0321|M.smegmatis_MC2_155 LAPAESAGLIEFGTRIR-FHHPLVRSAAYRAASVEDRRAAHHALAEATDA
TH_3225|M.thermoresistible__bu LAPAEAARVIQFGPRMR-FFHPLMRSAAYRAADPRDRRAVHRALAEATDP
MAB_3361|M.abscessus_ATCC_1997 IAPAEAADLVELSTRVR-FRHPLVRSAVYISANPLERRRIHGVLAGATDP
MMAR_0085|M.marinum_M AAPAEAAGLIAAQGSVR-FRHPLIRAAVYHSSSAAERRRVHAALAASIAG
Mvan_3871|M.vanbaalenii_PYR-1 IVEAESIELMRINAGRVDFRHPLVRSAVYAAADAQTRRDVHRAVAAAMPA
Mflv_4504|M.gilvum_PYR-GCK LERAEAAGIVVLEGNRVRFTHPLLAGGVYTDAGPTARRAMHRAIASVES-
MUL_2555|M.ulcerans_Agy99 LHLARCAAELTIRRGDACQAIELLRRAGELSDRPRRREQLLASAAFVALQ
MAV_0578|M.avium_104 EAMGLVTVERTPRALMARLAHPLFGELRRAGAGEMYLSTIRGRLATRLAQ
MLBr_02341|M.leprae_Br4923 VPARRLLRVAEPRQPTWFSESTLVGREWELATLAAMLDRSIGGRGSVVGL
:
Mb0393|M.bovis_AF2122/97 LTEPERTLFR-RLAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKS
Rv0386|M.tuberculosis_H37Rv LTEPERTLFR-RLAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKS
MSMEG_0321|M.smegmatis_MC2_155 VTDPDRRAWH-AANAAAGPSDAVATELEASAGRAQTRGGIAAAATFLERA
TH_3225|M.thermoresistible__bu GADPDRRAWH-AANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERA
MAB_3361|M.abscessus_ATCC_1997 GADPDRRAWH-RAHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRA
MMAR_0085|M.marinum_M PDDDDHRVWH-RAHAAEAPDAQTADDLERSAERARARGGLSAAASFLEHA
Mvan_3871|M.vanbaalenii_PYR-1 AAHT-RRVWH-LSEAVVGPDDAVADDLVDLAEKATARGAHGVAANALTRS
Mflv_4504|M.gilvum_PYR-GCK --HPELRARH-LALAASSGDDEIFAALDQAADSARARGAPAAAAELMDLA
MUL_2555|M.ulcerans_Agy99 AAQLDEAERL-LADAGLGGGASASALLISSFISLYRYG--DVTATHRRLV
MAV_0578|M.avium_104 DQDADMQATVRRALLTLESDLDPQPELYLESARHAMTLLDLDLADRLANA
MLBr_02341|M.leprae_Br4923 VGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDVVAQLVRAV
:
Mb0393|M.bovis_AF2122/97 LVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAAR
Rv0386|M.tuberculosis_H37Rv LVMADDNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAAR
MSMEG_0321|M.smegmatis_MC2_155 AVLSADLHLRGARAVAAAQAKRDAADLQAAYELLAIAELSPLSDLQRAQ-
TH_3225|M.thermoresistible__bu VVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWAR-
MAB_3361|M.abscessus_ATCC_1997 TELTADPAARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDPLARAR-
MMAR_0085|M.marinum_M TKLTPDPFVRASRALDAAMTSLEAGMPDSATRLVASAAAAADDELIAAR-
Mvan_3871|M.vanbaalenii_PYR-1 AELTNDDVLRCARLIRAGEAAWFAGHLTRARGLIDDAEAIAAGPDTLTQ-
Mflv_4504|M.gilvum_PYR-GCK LGLGAHDPMR---RLKAAENHFLAGDTAKAAAALGEVGSIEPPILRAMA-
MUL_2555|M.ulcerans_Agy99 ERLQSADDLDGETLTRMVNLLLAVSMFAADPALWQITDGLVDSLADRLG-
MAV_0578|M.avium_104 AARAGAPGAAGVRAMNLVLLGRGEQAEEALRAITDGADGDASDRHYWAT-
MLBr_02341|M.leprae_Br4923 AQISGLDDRSARARVREQIPDADTQDLLLLDDLLGIADPAVELPRLDPD-
Mb0393|M.bovis_AF2122/97 VDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRVW
Rv0386|M.tuberculosis_H37Rv VDNPGPSDYSHCLDQAETEIDNLRAAFVWNRENSDTEGALALASSLLRVW
MSMEG_0321|M.smegmatis_MC2_155 -------------------IARLRAQMEFSHSRREDSGPAQLRDAAAMLL
TH_3225|M.thermoresistible__bu -------------------AVHLRAQLEFARSRAGDAGGPPVGQTAAALL
MAB_3361|M.abscessus_ATCC_1997 -------------------ATRLRAKIAFAESRVGAFGSVTVSEAAIGLV
MMAR_0085|M.marinum_M -------------------CELIRAKIAFAASRG--------SDAPPLLL
Mvan_3871|M.vanbaalenii_PYR-1 -------------------ISALRGHIALR--------SGSLRDAHDLLV
Mflv_4504|M.gilvum_PYR-GCK --------------------TSLLATVRMYDN--------EHRQAVDLLR
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ---------------------VRAANLVWMLGRP--------ADAALVLD
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb0393|M.bovis_AF2122/97 MTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAA
Rv0386|M.tuberculosis_H37Rv MTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIFVDAAA
MSMEG_0321|M.smegmatis_MC2_155 DAARRLES----LDDELALQ--THLEAIAAAMYAGHLGA--PDALLTTAA
TH_3225|M.thermoresistible__bu TAAQLLQD----VDAPAARE--SYLEAFAALMYAGRLAP--SGALLEAAD
MAB_3361|M.abscessus_ATCC_1997 EAARCLEN----LDDNLARE--TYLDAVGAAMYGGRLCP--RGGAVEVAE
MMAR_0085|M.marinum_M AAAQRMQR----LDPSESRK--AYLGAVLASILVGRMATDQHNSSPSVAK
Mvan_3871|M.vanbaalenii_PYR-1 DAAARTDA-------------------AEADATVGLLADAVTACFYMCDT
Mflv_4504|M.gilvum_PYR-GCK SALDDAADN-------------------VPVQVQVLLRLSFALNSIGELD
MUL_2555|M.ulcerans_Agy99 -----------------------------------ELSVIYRDAWADAAR
MAV_0578|M.avium_104 GLAARPETP-----------------AQAAARCAVQACLDAVAARCQLAA
MLBr_02341|M.leprae_Br4923 -------------------------------ARRRRLTALINVAQLALSR
Mb0393|M.bovis_AF2122/97 GMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAID
Rv0386|M.tuberculosis_H37Rv GMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAID
MSMEG_0321|M.smegmatis_MC2_155 AAQAAVDRLASRDDPIALLLDGVAKCLTGDVGDAAVPLRKALTAWCSAAQ
TH_3225|M.thermoresistible__bu AVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELAR
MAB_3361|M.abscessus_ATCC_1997 PARLAPAGAQP-ARPSDLLLDGLARRITHGAAASAQTLGEALTLIRCEAD
MMAR_0085|M.marinum_M AASNAPAAPHP-PRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLRERD
Mvan_3871|M.vanbaalenii_PYR-1 AAGLALADRIEVLLPACRTGSARTRGQLAIGVARVIAGGDGMRWLRIAVE
Mflv_4504|M.gilvum_PYR-GCK DARRYARDAVKLAEELGFPGATSAALAWAVHVDFQCGRGLDETALARAMK
MUL_2555|M.ulcerans_Agy99 RGRTVTQRLKEQLDRLAELEPWDVMR------------------------
MAV_0578|M.avium_104 ERARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATT
MLBr_02341|M.leprae_Br4923 PAVFVVEDVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHG------
Mb0393|M.bovis_AF2122/97 LARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSN
Rv0386|M.tuberculosis_H37Rv LARAVDDRWRLAQILTFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSN
MSMEG_0321|M.smegmatis_MC2_155 HGDGAVLPWIFVGYPIVQESAVDELWDDTLMERLADAMVRYTRDAGALAI
TH_3225|M.thermoresistible__bu SRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDAGALAG
MAB_3361|M.abscessus_ATCC_1997 R--PANTSWMEQAFPIALESATHEVWDDDMWHHLATRAVHIAREVGALSL
MMAR_0085|M.marinum_M IG------VAEPGWHDLTARVCLDLFDQDAYNFLAARQVEDLRAAGALTM
Mvan_3871|M.vanbaalenii_PYR-1 TLNNEPSVLDDPRRPDWSIVGALFLRETAAGRDLMQRVVQDRRKRTAIGA
Mflv_4504|M.gilvum_PYR-GCK LYDSTFDVPIIFRAPFVHALAMSWTGRLEQAHQELTAVRGVCLERGAESD
MUL_2555|M.ulcerans_Agy99 -----------------VALAGYYVDLIDDFRSVLVPLADREIEGGAATI
MAV_0578|M.avium_104 SFEAS---HMRFWFGAVYGRACRLTGRIDEFVSTARRLADSARDVPGLAY
MLBr_02341|M.leprae_Br4923 ------------ALRHVVGAQIIAVAPLSDVETSTLVAELLGLDQSVTQI
Mb0393|M.bovis_AF2122/97 ALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAF
Rv0386|M.tuberculosis_H37Rv ALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAF
MSMEG_0321|M.smegmatis_MC2_155 LPAALSCRAGAHLLSGEFGTAGNLLDEANAIAVAIADQ-PLRYHRL---H
TH_3225|M.thermoresistible__bu LPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHRL---I
MAB_3361|M.abscessus_ATCC_1997 LPAALIYRAGMHVHAGELDAAAELVQEADAISAATGHA-PIRYHSL---I
MMAR_0085|M.marinum_M LPVALVTFAGVCVSAGNFGQADALLDESAAIIAATGAP-PRPAIKT---Y
Mvan_3871|M.vanbaalenii_PYR-1 LPNLLFHTARDDATTDNWQSALASYTESVALARETSQSTDLAASLAGLAW
Mflv_4504|M.gilvum_PYR-GCK MMAIAGFLAINHLWRGQITDAEAEAAEAVERAEQLGGDDVLIIPMTVRGA
MUL_2555|M.ulcerans_Agy99 ALATLALVAAYQLASGQWAEAVDTSQRGVALCSQHHYELFGYQLRGYLGV
MAV_0578|M.avium_104 ANLALLLGNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASYFALAE
MLBr_02341|M.leprae_Br4923 GELITERAAGNPFFAQEITRELAERGVLTGERGRYACSTDVAEVCVPATL
Mb0393|M.bovis_AF2122/97 ALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQ
Rv0386|M.tuberculosis_H37Rv ALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQ
MSMEG_0321|M.smegmatis_MC2_155 LAAWRGSTAETIAMIDSATAMAHR--------------------------
TH_3225|M.thermoresistible__bu IAAWRGDAVEAARLIEAAAADGEA--------------------------
MAB_3361|M.abscessus_ATCC_1997 LAAWRGSEPTAIRLIDEAMRDGAA--------------------------
MMAR_0085|M.marinum_M LAAYRGQEQICREGVQQTVDSAAS--------------------------
Mvan_3871|M.vanbaalenii_PYR-1 LQARMGRFAECRVNAAEARQLARR--------------------------
Mflv_4504|M.gilvum_PYR-GCK IAAYAGRVDDARADARWVLAAVRN--------------------------
MUL_2555|M.ulcerans_Agy99 ISACRGDVVRARELAAQVRVWAEP--------------------------
MAV_0578|M.avium_104 AHGRLGHPAQANEAIAGARSCVPP--------------------------
MLBr_02341|M.leprae_Br4923 QATIAARIDRLSPPAKQLLVAAAV--------------------------
.
Mb0393|M.bovis_AF2122/97 HASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQS--
Rv0386|M.tuberculosis_H37Rv HASEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQS--
MSMEG_0321|M.smegmatis_MC2_155 -------NGEGRLLAVLGYFAALLYNGAGRYEEAYAAIRPACSTKNLG--
TH_3225|M.thermoresistible__bu -------RGEGRLMGLTGYAAALLYNGIGRYREALAAARTTCEYEDLG--
MAB_3361|M.abscessus_ATCC_1997 -------RGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACEHEDLG--
MMAR_0085|M.marinum_M -------RGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGARYDDVG--
Mvan_3871|M.vanbaalenii_PYR-1 ----HHITFAHLWAQFALGDSALAEGNAGEAIVHYQGMESLLTDNRFR--
Mflv_4504|M.gilvum_PYR-GCK -------RKASHIADWPGMTLCFLEESLGNHREALAALDDSFIAAGPPTT
MUL_2555|M.ulcerans_Agy99 -------RRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITAPGEFPP-
MAV_0578|M.avium_104 --------DFLFMHTGLALATGWALAAGGQLREAVATAQAAARLARDR--
MLBr_02341|M.leprae_Br4923 -------------IGFRFGSDLLASLGIDLSVDELIDANLVDQVRFTAP-
Mb0393|M.bovis_AF2122/97 --MTGHHLA-MALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLP
Rv0386|M.tuberculosis_H37Rv --MTGHHLA-MALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLP
MSMEG_0321|M.smegmatis_MC2_155 --FGGWSLV-ELIEAAVHTGRREAAEEAADRLAAQAGASGTDWGLGALAG
TH_3225|M.thermoresistible__bu --FYSWCLH-ELVEAAARVGETDTAHRALGDIEERAGASGTPWGLGALAG
MAB_3361|M.abscessus_ATCC_1997 --LYSWCLI-ELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVAR
MMAR_0085|M.marinum_M --MCGYLLG-ELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALGIGAS
Mvan_3871|M.vanbaalenii_PYR-1 --DVDLAPGPELAEAHMRHGDAAAAHEVAVGYLGRAQEKSQPWALARAHR
Mflv_4504|M.gilvum_PYR-GCK ELMYAWHLP-DAIEAMVGVGRLDDAEILTAALERNGVEHDRRWMRAVGAR
MUL_2555|M.ulcerans_Agy99 LALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRLAIATGA
MAV_0578|M.avium_104 ---GQPTHELACIQAAAQWGDAAGAVRARALADALSLPLADAIACHAEAL
MLBr_02341|M.leprae_Br4923 ---VEYAFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVDQHAV
:
Mb0393|M.bovis_AF2122/97 DVLECL----AGLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYV
Rv0386|M.tuberculosis_H37Rv DVLECL----AGLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYV
MSMEG_0321|M.smegmatis_MC2_155 ARAMLA----DHDTADALFTEAIERLQRTRIAVELARTHLRYGEWLRRVN
TH_3225|M.thermoresistible__bu ARALLA----DGDEADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREH
MAB_3361|M.abscessus_ATCC_1997 SRALIT----VGHDAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCN
MMAR_0085|M.marinum_M ATALVS----DGSIADAAYREAITHLRRSPVAVHLARTHLTYGEWLRRER
Mvan_3871|M.vanbaalenii_PYR-1 AMALTAG---EPGVCEAHFSEALRLHELNPDRFEAARTRLAFGSSLRRIK
Mflv_4504|M.gilvum_PYR-GCK CRAMLLAAHGDVAAAEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLR
MUL_2555|M.ulcerans_Agy99 AEALCAS----DERAPALFEKVLGHPAVASFPFEHARIRLAYGMRLRRLR
MAV_0578|M.avium_104 RAGNGE-----ALLTVAAAYRAIGDAAAAADAAAQASAAFVEGQQHQRGR
MLBr_02341|M.leprae_Br4923 LIAEHL-------EAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATK
.
Mb0393|M.bovis_AF2122/97 QSVTALRDAMGEKDFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWES
Rv0386|M.tuberculosis_H37Rv QSVTALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWES
MSMEG_0321|M.smegmatis_MC2_155 RRPDARRHLGVAFDMFTRMGA-AGFAERARRELTATGEKVRKQPVSSGDE
TH_3225|M.thermoresistible__bu RRGEARRELNEAHGMFTRMGA-QGFAERSRRELIAVGEKVRRQPLTSGDE
MAB_3361|M.abscessus_ATCC_1997 RRSDARTELTAAHGSFVNMGT-AAFAERAERELRATGAKVRKRSASSEKA
MMAR_0085|M.marinum_M RRSEARSQLRIAYDMFAQMGA-AGFAERARRELSATGEAVYVQPTGITVD
Mvan_3871|M.vanbaalenii_PYR-1 KRVAARPHLRAALEDFERLGA-RPWADAAADELEATGERARRGGTEYSAL
Mflv_4504|M.gilvum_PYR-GCK QKATAAKNLTDALHTFEQLGT-PLWAQRARSELAR-------AVVAPAEG
MUL_2555|M.ulcerans_Agy99 RYRNARVVLRAAAEIFAGLGA-EPWTQRARNELRAAGTAVRHSAAVGPAP
MAV_0578|M.avium_104 YAAALAGELAEECGGLCTPAL----------------------RTPAGLK
MLBr_02341|M.leprae_Br4923 IADALTAEDPHRAAMCIAPRT-----------------------RLCGIA
Mb0393|M.bovis_AF2122/97 LTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQ
Rv0386|M.tuberculosis_H37Rv LTPTEIDVVRLVGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQ
MSMEG_0321|M.smegmatis_MC2_155 LTAQEAQIARLAADGLTNQEIGSQLFISTHTVEWHLRKVFVKLGIGSRRQ
TH_3225|M.thermoresistible__bu LTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQ
MAB_3361|M.abscessus_ATCC_1997 LTAQEAQIARMAGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQ
MMAR_0085|M.marinum_M LTTQESHIARLARDGYTNAEIAGLLFISARTVEWHLSKIFAKLGVTSRRE
Mvan_3871|M.vanbaalenii_PYR-1 LTSQELRIAQMLGRGATTKEAAAALFLSPKTVEYHLRNVYHKLAISSRSE
Mflv_4504|M.gilvum_PYR-GCK LTPSEQKVAEMAAAGATNKDIAAAMFISSKTVEHNLTRIYRKLGISSRAE
MUL_2555|M.ulcerans_Agy99 LTAQERLVAELAAKGLSNKEIAARLCLSPRTVGAHLYRLFPKLGVTNRAG
MAV_0578|M.avium_104 LSGRQRDVIELAVAGLSNRQIAERLVMSVRTVEGHIYRACQRVGAQSRDE
MLBr_02341|M.leprae_Br4923 WRGRFNSSSGFDEVRQLCNATGDKAPLAVATVGPAIDHVYQDRLH-----
: . :: ** : .
Mb0393|M.bovis_AF2122/97 LAQAAARRT------
Rv0386|M.tuberculosis_H37Rv LAQAAARRT------
MSMEG_0321|M.smegmatis_MC2_155 LRTIEWAG-------
TH_3225|M.thermoresistible__bu LRAAPRVTATW----
MAB_3361|M.abscessus_ATCC_1997 LRSGR----------
MMAR_0085|M.marinum_M LRAILMESP------
Mvan_3871|M.vanbaalenii_PYR-1 LKAVVQDRADG----
Mflv_4504|M.gilvum_PYR-GCK LGRRMDQPGL-----
MUL_2555|M.ulcerans_Agy99 LHDALDAIHAAPDQI
MAV_0578|M.avium_104 LATIIRSRPAGRES-
MLBr_02341|M.leprae_Br4923 ---------------