For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSKLLPRGTVTLLLADVEGSTWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFACA SDAVAAALDLQRARLAPIRLRIGVHTGEVALRDEGNYAGPTINRTARLRDLAHGGQTVLSGVTESLVIDR LPDKAWLVDLGTHALRDLSRPERVMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRL VTDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGRAWFVDLAPITDPDLVPVTVAGALGLHDQPGRSTTDT VLRFLGGRPALVVLDNCEHLLDATAALVLALVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSDEAVEM FCYRAQRVRPDFRLTDDNSAAVTEICKRLDGLPLAIELAAARLRSMTLDEIIDGLRDRFALLTGGARTAA HRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFVDDAQAVACSGDVQRYQVLDEITLLVDKSLVMAD DNSGRTCYRLCETMRHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPSDYSHCLDQAETEIDNLRA AFVWNRENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILADENARHLEVAAAVRARALADKALLDIF VDAAAGMEQAQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQIL TFQAVDAVVAGDPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQLMRGELAAAAAQFGEVVDEAEAS QEVLHKANSLQGLAFALAYQGELSAARAAADAALEAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEA AWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGHHLAMALATRARIAVAEGKREEAE RDAHKALACAAESGAHLDLPDVLECLAGLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVT ALRDAMGEKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVGEGLANKDIATR LFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0386 | - | - | 100% (1085) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR/UHPA-FAMILY) |
| M. tuberculosis H37Rv | Rv2488c | - | 0.0 | 56.53% (1088) | LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1358 | - | 0.0 | 53.45% (1087) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0393 | - | 0.0 | 99.91% (1085) | LuxR/UHPA family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1156 | - | 2e-14 | 26.26% (514) | regulatory protein, LuxR |
| M. leprae Br4923 | MLBr_01753 | - | 0.0 | 51.56% (1088) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3361 | - | 3e-12 | 27.11% (509) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0123 | - | 0.0 | 56.34% (1097) | LuxR family transcriptional regulator |
| M. avium 104 | MAV_2364 | - | 2e-13 | 24.62% (528) | TPR repeat-containing protein |
| M. smegmatis MC2 155 | MSMEG_0545 | - | 6e-23 | 42.86% (175) | transcriptional regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3225 | - | 1e-13 | 25.78% (547) | PUTATIVE regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2743 | - | 1e-104 | 42.96% (582) | LuxR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5928 | - | 0.0 | 59.74% (1088) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0386|M.tuberculosis_H37Rv ------------------------------MSKLLPRG-TVTLLLADVEG
Mb0393|M.bovis_AF2122/97 ------------------------------MSKLLPRG-TVTLLLADVEG
MMAR_0123|M.marinum_M --MLASMSEIDPR-----AEAPLVDWSDVDMGELLPTG-TVTLLLADVEG
Mvan_5928|M.vanbaalenii_PYR-1 ------------------------------MSELVPTG-TVTLLLADVQG
MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_0545|M.smegmatis_MC2_155 ------------------------------MTEKLSTG-TKTLLMARVDR
MUL_2743|M.ulcerans_Agy99 ----------------------------------------MTFLFTDVEG
MAB_3361|M.abscessus_ATCC_1997 ----------------------------------------MLRGQAGVGK
TH_3225|M.thermoresistible__bu -----MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGK
Mflv_1156|M.gilvum_PYR-GCK ---------------------MKAVDDFLAGLQQLQPAGLLIEGEAGIGK
MAV_2364|M.avium_104 --------------------------------------MEFRRSLAALNN
:
Rv0386|M.tuberculosis_H37Rv STWLWETHPDD--MGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAF
Mb0393|M.bovis_AF2122/97 STWLWETHPDD--MGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAF
MMAR_0123|M.marinum_M STRLWQNQPEP--MTAAVAHLDSVLATTVATHHGVRPVEQGEGDSFVVAF
Mvan_5928|M.vanbaalenii_PYR-1 STQLWETQPET--MTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAF
MLBr_01753|M.leprae_Br4923 LAELSETQPDE--AADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATF
MSMEG_0545|M.smegmatis_MC2_155 AEELWQTELDQ--TIAAIPWLRASMAHLIALNDGT--LQRDASDSFVAAF
MUL_2743|M.ulcerans_Agy99 STRLWESDPDR--MRAALAAHDAVLTRTIQTHRGWLFKHTG--DGVCAAF
MAB_3361|M.abscessus_ATCC_1997 TALLRYVLGKA--SGQLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIP
TH_3225|M.thermoresistible__bu TALLGQLLGDA--AGMRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLP
Mflv_1156|M.gilvum_PYR-GCK TTMLAGVVDAARQAGFRVLSAHGDQSGSGLAHAAIADLFAGVQTDILDGL
MAV_2364|M.avium_104 GEFHGVALVGD--GGVGKSTLARMLAKTVESAGRTVRFALGTQTGWAVPL
:
Rv0386|M.tuberculosis_H37Rv -ACASDAVAAALDLQRARLAPIRLRIGVHTGEVALRDEG---NYAGPTIN
Mb0393|M.bovis_AF2122/97 -ACASDAVAAALDLQRARLAPIRLRIGVHTGEVALRDEG---NYAGPTIN
MMAR_0123|M.marinum_M -ASAREAIACALDLQRSPLGPIRLRIGVHTGDIQLRDPNDPTNYIGPTIN
Mvan_5928|M.vanbaalenii_PYR-1 -TRASDAVACALALQRAPLAPIRLRIGVHTGEVRLRDEG---NYVGPTIN
MLBr_01753|M.leprae_Br4923 -ARASDATACALDLQLAPIVPVRFRIALHTGEVQISNDD--VNNVVFMMV
MSMEG_0545|M.smegmatis_MC2_155 -DRASDAVMCALDLQLAPLEPFALCIGVHAVEHTDSADS----------D
MUL_2743|M.ulcerans_Agy99 -ASPRSAVDAAVDAQRALELPVRMGLATGEAEPHDADYFG------AVLN
MAB_3361|M.abscessus_ATCC_1997 -DPQREALTIAFGTR-SGPPPDRFLIGLAVLSLLAAAAEH-----QPVLC
TH_3225|M.thermoresistible__bu -SPQRDVLNVAFGRG-AGPAPGRFLVGLAVLNLLAAAGAD-----QPLLC
Mflv_1156|M.gilvum_PYR-GCK PELQRRAADGVLRRGDGTGGPTDERVIAAALLGAVHGSATR----TPVLV
MAV_2364|M.avium_104 GAFSRAVSLGVGHEPAIMLAAAHNTLGQDKNLVVVVDEAQ---LLDPLSA
. . . :
Rv0386|M.tuberculosis_H37Rv RTARLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPER
Mb0393|M.bovis_AF2122/97 RTARLRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPER
MMAR_0123|M.marinum_M RTARIRELAHGGQTVISGATQLLVVDQLPDGAWLADLGLHPLRDLPRPER
Mvan_5928|M.vanbaalenii_PYR-1 RTARLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPER
MLBr_01753|M.leprae_Br4923 QAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVR
MSMEG_0545|M.smegmatis_MC2_155 GAARLRDIARGGQTLISAAAAALVSARMPAHAALT-----PLRDRVRHEP
MUL_2743|M.ulcerans_Agy99 RAARVMATGHGGQILLTDSTANLISG-----VDLLDLGSRRLRDLPAPVR
MAB_3361|M.abscessus_ATCC_1997 VIDDAQWLDRVSLQTLAFVTRRLGSEPVAMLFAVRDGTDSELAGLP-ELT
TH_3225|M.thermoresistible__bu VIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRDDIHEALVGVP-ALA
Mflv_1156|M.gilvum_PYR-GCK AVDDVQWLDPSSVAVLAFVARRVKGRVGFVVAERPGVGPGLPAATWLQVG
MAV_2364|M.avium_104 TLVNQLAAGRSARLIVTIRSGEPVLDAVTALLKERLLLTVHVDPFTREQT
. : :
Rv0386|M.tuberculosis_H37Rv VMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQIT--EVHRLV
Mb0393|M.bovis_AF2122/97 VMQLCHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQIT--EVHRLV
MMAR_0123|M.marinum_M VMQLCHSGLQNDFPPLRTTKSIAVHRMPARLTRFVGRIAQMA--DVRSLL
Mvan_5928|M.vanbaalenii_PYR-1 VVQLCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMA--QVRGLM
MLBr_01753|M.leprae_Br4923 VMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIK--ELQELL
MSMEG_0545|M.smegmatis_MC2_155 VYQLNHPGLR--------TEADEVPHLP------YGRVVR----------
MUL_2743|M.ulcerans_Agy99 VFQVRAPGLRTDFPALRAPDTSPG-NLRPALTSFVARAAEIG--QVQTAL
MAB_3361|M.abscessus_ATCC_1997 VHGLRAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLE--LPRDMT
TH_3225|M.thermoresistible__bu VPGLADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLE--VPRTYA
Mflv_1156|M.gilvum_PYR-GCK TGALTRLPVAPMSLGALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALE
MAV_2364|M.avium_104 ELLAGAVLGGPVDTRLVDELFERSAGNLLLLRGFLTAGVESG-------A
Rv0386|M.tuberculosis_H37Rv TDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGR-AWFVDLAPITDPDLVP
Mb0393|M.bovis_AF2122/97 TDNRLVTLTGAGGVGKTRLAAQLAAQIAGEFGR-AWFVDLAPITDPDLVP
MMAR_0123|M.marinum_M ADNRLVTLTGAGGAGKTRLAVEIAASAVDEFGDGLWYVDLAPVSHAEAVP
Mvan_5928|M.vanbaalenii_PYR-1 DANRLVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVA
MLBr_01753|M.leprae_Br4923 TEKRLLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFP
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 QVHRLVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVP
MAB_3361|M.abscessus_ATCC_1997 AEELAGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDV
TH_3225|M.thermoresistible__bu VGELAGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGDS
Mflv_1156|M.gilvum_PYR-GCK LARVADGAGSRPGQRLPESLSELVRLRVDGLAEDVRDVLLVAASATSPTV
MAV_2364|M.avium_104 LVHTEQGWQLQGPLRGDRELHDALEYRLQSLSSEEREVVEVLATAELLEW
Rv0386|M.tuberculosis_H37Rv VTVAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLA
Mb0393|M.bovis_AF2122/97 VTVAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLA
MMAR_0123|M.marinum_M VTVARALGLSDQPGRSTVDALARFIGEHQVLVVLDNCEHLLDATAALLLE
Mvan_5928|M.vanbaalenii_PYR-1 ITVARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATLIDA
MLBr_01753|M.leprae_Br4923 ITVL--------------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTT
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 DAVAAVLGITQQAGKTVTQSVATALERRVRLLVFDNCEHVRDAAADLIEA
MAB_3361|M.abscessus_ATCC_1997 TLLAR---------------AAQQLGIPMHAIAPAEAADLVELSTRVRFR
TH_3225|M.thermoresistible__bu ALFLR---------------AAALMGIAVDALAPAEAARVIQFGPRMRFF
Mflv_1156|M.gilvum_PYR-GCK DLLAKAVG-------------VTPAAVTGLVEAAEVEGIVVIDGNRIRFT
MAV_2364|M.avium_104 EILRD--------------------ICDADAMASLERRGLIQLVTDGSHT
Rv0386|M.tuberculosis_H37Rv LVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSD----EAVEMFCYRAQ
Mb0393|M.bovis_AF2122/97 LVKACRGVRLLATCREPLRVEGEVSYRVPSLSLSD----EAVEMFCYRAQ
MMAR_0123|M.marinum_M LTGRCPAVRLLATSREPLGVPGEVTFLVPSLSVT-----EATELFTDRAR
Mvan_5928|M.vanbaalenii_PYR-1 LLGACPALAMLATSREPIAVAGEQTWRVPPLALDD----DAIELFTDRAR
MLBr_01753|M.leprae_Br4923 LLGACPSLTILATSREPIGVAGEVIWRVSMLSPAD----EAVELFTERAA
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 ILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVSAAGTLFVERAQ
MAB_3361|M.abscessus_ATCC_1997 HPLVRSAVYISANPLERRRIHGVLAGATDPGADPD-----------RRAW
TH_3225|M.thermoresistible__bu HPLMRSAAYRAADPRDRRAVHRALAEATDPGADPD-----------RRAW
Mflv_1156|M.gilvum_PYR-GCK HPVLANGIYAGADPQRRREVHRRLADLKTDPELR--------------AR
MAV_2364|M.avium_104 LVQLNHPMLGEAATRHAGVVRSRQLNGILAKTLRK------------HLR
Rv0386|M.tuberculosis_H37Rv RVRPDFRLTDDNSAAVT-EICKRLDGLPLAIELAAARLRSMTLDEIIDGL
Mb0393|M.bovis_AF2122/97 RVRPDFRLTDDNSAAVT-EICKRLDGLPLAIELAAARLRSMTLDEIIDGL
MMAR_0123|M.marinum_M RVRPDFAVTDDNTTAVT-EICNRLDCMPLAIELAAARVRALSIDEIRTGL
Mvan_5928|M.vanbaalenii_PYR-1 RARPDFIISADDAAAVS-EICHRLDGMPLAIELAAARVRALSLTEIVDGL
MLBr_01753|M.leprae_Br4923 LVQPGFSVTDGNRQIVT-EICQRLDGMPLAIELAAARIRTLSLTEIADGL
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 SVAPGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRMASMTPIEVRDRL
MAB_3361|M.abscessus_ATCC_1997 HRAHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPA--
TH_3225|M.thermoresistible__bu HAANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPG--
Mflv_1156|M.gilvum_PYR-GCK HLALASTVADETTLTTLDAAADAARARGAPAAAAELLEWAMQLGGDSVS-
MAV_2364|M.avium_104 AAGRRSQISDPRGRIQLAQFIMRSDLEPDLDVVIKAAADAMAMSNVVLG-
Rv0386|M.tuberculosis_H37Rv RDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCF
Mb0393|M.bovis_AF2122/97 RDRFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCF
MMAR_0123|M.marinum_M HDRFRLLTGGARTVVRRQQTLRASVDWSHALLTEPERVLFRRIAVFLGGF
Mvan_5928|M.vanbaalenii_PYR-1 HDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAVFAGGF
MLBr_01753|M.leprae_Br4923 DDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTF
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 DHRFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVLLERCSVFAGGF
MAB_3361|M.abscessus_ATCC_1997 ------ARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATR
TH_3225|M.thermoresistible__bu ------LRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVH
Mflv_1156|M.gilvum_PYR-GCK ----------RRIRAAEHHVVAGDMRRAATLLEQALVDLRPGVLCAIALN
MAV_2364|M.avium_104 -EQLATFAVDRGGGLAAALVLAEAVSWQ-GRGEEADSILLGADVDDADEW
Rv0386|M.tuberculosis_H37Rv FVDDAQAVACSGDVQR-YQVLDEITLLVDKSLVMADDNSGRTCYRLCETM
Mb0393|M.bovis_AF2122/97 FVDDAQAVACSGDVQR-YQVLDEITLLVDKSLVMADDNSGRTCYRLCETM
MMAR_0123|M.marinum_M DLDAAQAVAGDSQVQR-YQVVDELALLVDKSLVIAESGGGPTRYRLLETV
Mvan_5928|M.vanbaalenii_PYR-1 DLDGAQAITVDGEVHR-YEVVDLLTLLVDKSLLIAENTAGRTRYRLLETV
MLBr_01753|M.leprae_Br4923 DLKVAYAVGHDDLEEP-DQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETV
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 DLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLSGRSRFSMLETI
MAB_3361|M.abscessus_ATCC_1997 LRAKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAV
TH_3225|M.thermoresistible__bu LRAQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAF
Mflv_1156|M.gilvum_PYR-GCK LLAGVRMVED-----------DYIRAVELLERARADADNDAVLVTTLLSL
MAV_2364|M.avium_104 LIARWGCLRAANLAWGCGDAEGATRVLAEVKQRLATEGSLQLIDALDVSI
Rv0386|M.tuberculosis_H37Rv RHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPS-DYSHCLDQAET
Mb0393|M.bovis_AF2122/97 RHYALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPS-DYSHCLDQAET
MMAR_0123|M.marinum_M RQYAQEKLAESGEVEAVRSRHVTYYKSVAKLLDAPTGT-DHERRLAQAED
Mvan_5928|M.vanbaalenii_PYR-1 RQYAQEKLGESGEADTLRARHRDHYTARAAELDAPSVA-GHERRLNQTDI
MLBr_01753|M.leprae_Br4923 RQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDI-DHEQLVEQVET
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 REFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEAYTWLTA
MAB_3361|M.abscessus_ATCC_1997 G----------------AAMYGGRLCPRGGAVEVAEPARLAPAGAQP-AR
TH_3225|M.thermoresistible__bu A----------------ALMYAGRLAPSGALLEAADAVQAAFARAPEGSR
Mflv_1156|M.gilvum_PYR-GCK G------------------FCLGMTGSFTAQLATVREAVAVAERAGVPAL
MAV_2364|M.avium_104 G------------------FFRGDIARTIELGPRLCEPDVVPMATVWAAV
Rv0386|M.tuberculosis_H37Rv EIDNLRAAFVWNRENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILA
Mb0393|M.bovis_AF2122/97 EIDNLRAAFVWNRENSDTEGALALASSLLRVWMTRGRIQEGRAWFDSILA
MMAR_0123|M.marinum_M ELDNLRSAFGWSLETRDFDSALELATSLHPVWMTRGQGREGLAWLEAGLG
Mvan_5928|M.vanbaalenii_PYR-1 EMDNLRAAFAWSRENANTDHSLLLASSLHPLWRARGRLQEGQAWFDAALT
MLBr_01753|M.leprae_Br4923 ELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMYEGLAWFDSIFE
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 ELANLRLAFRWTADNNDLDDAASIATWVGFLGFLVNRFEP----------
MAB_3361|M.abscessus_ATCC_1997 PSDLLLDGLARRITHGAAASAQTLGEALTLIRCEAD-RPANTS-------
TH_3225|M.thermoresistible__bu AVDAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEVVH------
Mflv_1156|M.gilvum_PYR-GCK TSRALAMWVHVSFQAGNGLDSAALLRAVDLEDPEDNTPIPFRAS------
MAV_2364|M.avium_104 ATCGALTAVGRFSEVGRIAAAGVRATAQCRAG------------------
Rv0386|M.tuberculosis_H37Rv DEN---------ARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQ
Mb0393|M.bovis_AF2122/97 DEN---------ARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQ
MMAR_0123|M.marinum_M NEAGLGNEAGLGNEDVQVSPSTLARALADKVTLLAWTGSMAG-----FDD
Mvan_5928|M.vanbaalenii_PYR-1 -----DYEARPG----EADPAVYARALADRAFMDGHVGITDR-----LDQ
MLBr_01753|M.leprae_Br4923 HKN---------IEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQ
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 -----------------------------------------------LTW
MAB_3361|M.abscessus_ATCC_1997 -------------------------------------------------W
TH_3225|M.thermoresistible__bu -------------------------------------------------W
Mflv_1156|M.gilvum_PYR-GCK --------------------------------------------------
MAV_2364|M.avium_104 --------------------------------------------------
Rv0386|M.tuberculosis_H37Rv AQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARA
Mb0393|M.bovis_AF2122/97 AQQALVIAREVDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARA
MMAR_0123|M.marinum_M AERALTIARELADPALLIRALVARG--VITAYDADVARPYFDEAAQLARE
Mvan_5928|M.vanbaalenii_PYR-1 AQKALAMARDIDDPALLVRALTACG--GLAAYNADVARPLLAEAVDLARS
MLBr_01753|M.leprae_Br4923 AQQALTMAREIGDSAVLARALTACG--FSSGYDTEVARPYFAEAVELART
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 VEEAIERAVDHPKLAFLHVLASQCY----TTGRVQEAIRYADEAARLLAT
MAB_3361|M.abscessus_ATCC_1997 MEQAFPIALESAT---------------HEVWDDDMWHHLATRAVHIARE
TH_3225|M.thermoresistible__bu LVPAFPVLQESAG---------------HELWDENLVDALSEAVVRQARD
Mflv_1156|M.gilvum_PYR-GCK AARGLSLALTG---------------------RLAEADGQLAAVAQRSAQ
MAV_2364|M.avium_104 ----------------------------AQRFAIGLAEVMAATAAGDYPA
Rv0386|M.tuberculosis_H37Rv VDDRWRLAQILTFQAVDAVVAG-DPVAARPAAQEARELAAAIGDHSNALW
Mb0393|M.bovis_AF2122/97 VDDRWRLAQILTFQAVDAVVAG-DPVAARPAAQEARELAAAIGDHSNALW
MMAR_0123|M.marinum_M LGDSWRLSQILSLQTRAAMAAG-DPIALEAAGEEGLRIAEAIGDRTTSRE
Mvan_5928|M.vanbaalenii_PYR-1 MGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRI
MLBr_01753|M.leprae_Br4923 QGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDRFVSLQ
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 --DRYEVPFGIEGWPSGACTSSGHPEQSVELCRTQLALGHDTHTLTLG--
MAB_3361|M.abscessus_ATCC_1997 VGALSLLPAALIYRAGMHVHAG----ELDAAAELVQEADAISAATGH-AP
TH_3225|M.thermoresistible__bu AGALAGLPQALVYRAGVHLLFG----EFGLADTLLTEAESITAATDHRGP
Mflv_1156|M.gilvum_PYR-GCK RGAEQDVMAVLGYRTLVAIWRG---RYAEADAYAADTMERAEQLGGSMVI
MAV_2364|M.avium_104 AERIHKRYAALATGLPAAEAMVDAMLGVLQLTRGELQEACATLDRSISQL
Rv0386|M.tuberculosis_H37Rv CRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALA
Mb0393|M.bovis_AF2122/97 CRWCLGYAQLMRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALA
MMAR_0123|M.marinum_M CRGALGWVRAWRGDPIGALHQLGEAIAEASAAHDLLLLMISQVVQGFTYA
Mvan_5928|M.vanbaalenii_PYR-1 CGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLA
MLBr_01753|M.leprae_Br4923 CRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALV
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 ---CLVLALTIKGQCDEAEQLADALIESAEATRNPAALCYALLAYGFTFR
MAB_3361|M.abscessus_ATCC_1997 IRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGRLLGAMGYAAGVLNN
TH_3225|M.thermoresistible__bu VRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYN
Mflv_1156|M.gilvum_PYR-GCK AFSICAAVAAYRGREDQARDQAAGALAQG--GDYVALTVWASATLAFLEV
MAV_2364|M.avium_104 SQGFPLPWQLVVGALQAQAEGARGDSAAAAVALRRVEEAYGPHVAVFLPE
Rv0386|M.tuberculosis_H37Rv YQGELSAARAAADAAL-EAAELGEYFAGMGYSALTTAALAAGDVQTAQHA
Mb0393|M.bovis_AF2122/97 YQGELSAARAAADAAL-EAAELGEYFAGMGYSALTTAALAAGDVQTAQHA
MMAR_0123|M.marinum_M YVGDADGACACADAVFTSSAELVGANEGLGYATAAIACQAAGDATAAWKA
Mvan_5928|M.vanbaalenii_PYR-1 QRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAA
MLBr_01753|M.leprae_Br4923 HR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEA
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 DTNPASALAAMR--------------------------------------
MAB_3361|M.abscessus_ATCC_1997 SLGRYELAFMAA--------------------------------------
TH_3225|M.thermoresistible__bu GIGRYREALAAA--------------------------------------
Mflv_1156|M.gilvum_PYR-GCK SRGNYEQALEAAEP------------------------------------
MAV_2364|M.avium_104 LELARAWERAAAG-------------------------------------
Rv0386|M.tuberculosis_H37Rv SEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGH
Mb0393|M.bovis_AF2122/97 SEAAWRNLSLALPLSAAVQRAFNAQAALAGGDLSAARRWCDDAVQSMTGH
MMAR_0123|M.marinum_M YQKARELVGMDPQMAGVFPFGALAPLVS--GDLSAARRWADDVVSTSYGC
Mvan_5928|M.vanbaalenii_PYR-1 SDSATRSFGPS-EVAGIQDPNVAAQIACTRGDLDTARSLVDGAVSITRGV
MLBr_01753|M.leprae_Br4923 SEACRPHLGADHGLVAIH-LELMAAVALARGDVIVARRLADNSVSATTGW
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 ----------------------------------RGLRIAQDTGNRNSET
MAB_3361|M.abscessus_ATCC_1997 -------------------------------------RRACEHEDLGLYS
TH_3225|M.thermoresistible__bu -------------------------------------RTTCEYEDLGFYS
Mflv_1156|M.gilvum_PYR-GCK ----------------------------------LVDLYRDFPGTELMSA
MAV_2364|M.avium_104 ----------------------------------------DTAGAQTQAM
Rv0386|M.tuberculosis_H37Rv HLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLA
Mb0393|M.bovis_AF2122/97 HLAMALATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLA
MMAR_0123|M.marinum_M YLSVALTARARVALAQGELGQADRDSHAALSCSAANGTTLGVADTLECLA
Mvan_5928|M.vanbaalenii_PYR-1 HRASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLECLA
MLBr_01753|M.leprae_Br4923 HQMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLA
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 HLAAVLCR---VEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLAVLA
MAB_3361|M.abscessus_ATCC_1997 WCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVARSRALIT
TH_3225|M.thermoresistible__bu WCLHELVEAAARVGETDTAHRALGDIEERAGASGTPWGLGALAGARALLA
Mflv_1156|M.gilvum_PYR-GCK CFMPDAIESLIAVGRLDEAEPLIAAFERNGAELDRPWQLAIGNRCRAMLL
MAV_2364|M.avium_104 QAAQTARKAGMHLVEMRARHAALRFGDRAQAARVDELASILNSPSAQAVA
Rv0386|M.tuberculosis_H37Rv GLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMG
Mb0393|M.bovis_AF2122/97 GLASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMG
MMAR_0123|M.marinum_M ELAATEGDRREAARLLASAEAIRHRTGEVRLKILDAHCEVVLAELRNELG
Mvan_5928|M.vanbaalenii_PYR-1 RVVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRDALG
MLBr_01753|M.leprae_Br4923 ELISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMG
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 AFFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALG
MAB_3361|M.abscessus_ATCC_1997 VGHDAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCNRRSDARTELT
TH_3225|M.thermoresistible__bu DGDEADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREHRRGEARRELN
Mflv_1156|M.gilvum_PYR-GCK SATGDLDGALAAAERAMAEHARLPMPFERARSALTLGEVLRRLRRRDAAA
MAV_2364|M.avium_104 G--HARGLAQHDGDLLDAAAHRFADLGALAFAADAAAQAASEHARRGDRR
Rv0386|M.tuberculosis_H37Rv EKDFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRL
Mb0393|M.bovis_AF2122/97 EKDFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRL
MMAR_0123|M.marinum_M EQDFAAVWGQGAVISTDEVISYVRRGRGTRRRPSSGWGSLTPTEHDVVRL
Mvan_5928|M.vanbaalenii_PYR-1 DKAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGL
MLBr_01753|M.leprae_Br4923 CKDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRL
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 DHAYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR-------------
MAB_3361|M.abscessus_ATCC_1997 AAHGSFVNMGTAAFAERAERELRATGAKVRKRSASSEKALTAQEAQIARM
TH_3225|M.thermoresistible__bu EAHGMFTRMGAQGFAERSRRELIAVGEKVRRQPLTSGDELTAQEAQIAGL
Mflv_1156|M.gilvum_PYR-GCK AVRDALAQFEELGVPLWVARARIALSGLAVSGSAVG-SELTDSERRIAEL
MAV_2364|M.avium_104 KEVESSTWAHALAGQCGSRTPALDAAARPLP--------FSGRERQIVNL
Rv0386|M.tuberculosis_H37Rv VGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT--
Mb0393|M.bovis_AF2122/97 VGEGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT--
MMAR_0123|M.marinum_M VQEGLSNKDIAARMFISPRTVQTHLTHVYTKLGLTSRIQLVHEVARHA--
Mvan_5928|M.vanbaalenii_PYR-1 VSEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT--
MLBr_01753|M.leprae_Br4923 VSEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN--
MSMEG_0545|M.smegmatis_MC2_155 --------------------------------------------------
MUL_2743|M.ulcerans_Agy99 --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 AGQGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR------
TH_3225|M.thermoresistible__bu AADGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW
Mflv_1156|M.gilvum_PYR-GCK AASGMSNRDVAETLFVSVKTIETNLSRVYRKLGIRSRAQLGRMLR-----
MAV_2364|M.avium_104 VAAGLSNREIADRLVISVRTVEGHLYRLFTKLGINNRDQLIQLIRRDAS-