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MALHRGLTADQRREQRRQQLIEAALDVIAEGGVGGLRVRAISERARLNDRYFYESFRDCQELMLAAYDDQ FARALTGVTAVIAESPPELKLRVREILEFAIGFLDEDPRRSRLLIELQTSEALAERRHEVLGVLTQIMVG LVGDGSGADDTATLTAVTVSSGLLELAAQWYREQIDISRAQLIEFATALVVTTADITGVLERQLAPPISG DSTDDGRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2901 | - | - | 100% (218) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1244 | - | 3e-18 | 30.73% (192) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 1e-11 | 27.61% (134) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0848c | - | 3e-13 | 26.80% (194) | hypothetical protein Mb0848c |
| M. gilvum PYR-GCK | Mflv_4631 | - | 2e-20 | 32.50% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0825c | - | 3e-13 | 26.80% (194) | hypothetical protein Rv0825c |
| M. leprae Br4923 | MLBr_00815 | - | 4e-05 | 20.57% (175) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3300c | - | 8e-34 | 41.62% (197) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3142 | - | 2e-17 | 30.46% (197) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 4e-20 | 31.77% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1355 | - | 1e-19 | 31.22% (189) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4000 | - | 4e-18 | 31.47% (197) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1200 | - | 2e-14 | 27.23% (202) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2901|M.vanbaalenii_PYR-1 ------------------------MALHRGLTADQRREQRRQQLIEAALD
MAB_3300c|M.abscessus_ATCC_199 ----------------------MPSRTYGGATSGERRARRRAALLDAALD
MSMEG_1355|M.smegmatis_MC2_155 ---------------------MTTPTRWAGVPLTDRRAERRALLVDAAFR
TH_4000|M.thermoresistible__bu ---------------------MTSPTRWAGVPLTDRRAERRALLIAAAYR
MAV_3986|M.avium_104 ---------------------MSSPSRWAGVPLKDRRAERRALLVEAAYR
Mflv_4631|M.gilvum_PYR-GCK -MGADATKVLRPTVVCQDGHVRTRSKRWGGRTGAERRAERRQRLIDAATE
MMAR_3142|M.marinum_M ---------------MFD--VRSRNTRWGGRTGAERRAERRQQLIEAATE
Mb0848c|M.bovis_AF2122/97 ------------------MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQ
Rv0825c|M.tuberculosis_H37Rv ------------------MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQ
MUL_1200|M.ulcerans_Agy99 ------------------------MRPYRGVEATERLATRRSQLLESGLE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
** *: .
Mvan_2901|M.vanbaalenii_PYR-1 VIAEGGVG--GLRVRAISERARLNDRYFYESFRDCQELMLAAYDDQFARA
MAB_3300c|M.abscessus_ATCC_199 LVAGSGVK--GLTVRGVCAEARLNDRYFYESFRSTDELVLAMLDEQMLAG
MSMEG_1355|M.smegmatis_MC2_155 LFGDGGE--TALSVRSVCRECGLNTRYFYESFADTDDLIGAVYDEVSALL
TH_4000|M.thermoresistible__bu LFGEGGE--AALSVRSVCRESELNSRYFYESFADVDELLGAVYDEVSAQL
MAV_3986|M.avium_104 LFGSEGE--AAVSVRSVCRECGLNTRYFYESFRDTDDLLGAVYDRVSEQL
Mflv_4631|M.gilvum_PYR-GCK IWSESGW--AAVTMRGVCAKTGLNDRYFYEDFKTRDELLVAAWDGVRNEM
MMAR_3142|M.marinum_M IWSESGW--AAVTMRGVCARTGLNDRYFYEDFKTREDLLVAAWDGVRNDM
Mb0848c|M.bovis_AF2122/97 LLGGAGG--PALTVRAVCRHAGLTERYFYESFADREHFVRAVYDDVC---
Rv0825c|M.tuberculosis_H37Rv LLGGAGG--PALTVRAVCRHAGLTERYFYESFADREHFVRAVYDDVC---
MUL_1200|M.ulcerans_Agy99 LLGSSDRDIAELTVRGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDL
MLBr_00815|M.leprae_Br4923 VFVDHGYH--AAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNL
: . : :. . :. :*: * .: . :
Mvan_2901|M.vanbaalenii_PYR-1 LTGVTAVIAE------SPP--ELKLRVREILEFAIGFLDEDPRRSRLLIE
MAB_3300c|M.abscessus_ATCC_199 SATIIEAIAK------SSTSKDPVVRTRAAVGSGLRFLTADPRRGRLLVE
MSMEG_1355|M.smegmatis_MC2_155 AADVEAAM--------EGAGNSLRARTRAGIAAVLGFSSADPRRGRVLFT
TH_4000|M.thermoresistible__bu AAEVETAMAAAVEGAGEGAGDSLRARTRAGIVAVLGFSSADPRRGRILFT
MAV_3986|M.avium_104 EEVIAAAI--------EQAGDSLRARTRAGIAAVLGFSSADPRRGRVLFT
Mflv_4631|M.gilvum_PYR-GCK LGEVSATLA-------ERIGQPPMETIRVTIAAVVDRIAEDPGRAKILLA
MMAR_3142|M.marinum_M LGEVSALFD-------ERVDRPPIETITAAIAIVVDRIARDPGRAHILLA
Mb0848c|M.bovis_AF2122/97 ----TRAMA----------TLTSAQTPREAVEQFVELMVDDPVRGRVLLL
Rv0825c|M.tuberculosis_H37Rv ----TRAMA----------TLTSAQTPREAVEQFVELMVDDPVRGRVLLL
MUL_1200|M.ulcerans_Agy99 ATTIQAAVA----------TVPPPEQARAGIAEIVRTIVGDARIGRLLFS
MLBr_00815|M.leprae_Br4923 VSSVQQALR---------TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFE
. : . * :::.
Mvan_2901|M.vanbaalenii_PYR-1 L-QTSEALAERRHEVLGVLTQIMVG----LVGDGSGADDTATLTAVTVSS
MAB_3300c|M.abscessus_ATCC_199 S-QATEGLAARRRDLVKTLAQVMADQGRVLLPADDALDPDLDLATFTLVS
MSMEG_1355|M.smegmatis_MC2_155 D-ARANPVLAQRRAVTQDLLREAVLSEGG-RLNPGSDPVAAQVGAAMYTG
TH_4000|M.thermoresistible__bu D-ARANPVLAARRAATQDQLREAVLTEGW-RLHPKSDPVAAQVGAAMYTG
MAV_3986|M.avium_104 D-ARTNPVLAARRRATQDMLRQGVLSEGW-RLNPRSDPVAAEVAAAMYTG
Mflv_4631|M.gilvum_PYR-GCK Q-HVGSSPLQDRRAVALQEATHLVIAASEPHLRPEADETALRMDTLVAVG
MMAR_3142|M.marinum_M Q-HVGSSPLQDRRAVALQEATQLVVEASRPHLREDADETALRMDTLVAVG
Mb0848c|M.bovis_AF2122/97 A-PAVEPALTRSGAEWMPNFIELLQRKLS---RIVDP-VLQKLVATSLIG
Rv0825c|M.tuberculosis_H37Rv A-PAVEPALTRSGAEWMPNFIELLQRKLS---RIVDP-VLQKLVATSLIG
MUL_1200|M.ulcerans_Agy99 T-HLANPVVVRKRTESSALFAMLSGQHAGDALRIPAN-DRIKVGAHFIVG
MLBr_00815|M.leprae_Br4923 NDNITEPRVAAQVRVATESCIDAVFALIS--ADSRLDPHRARMVAVGLVG
. : : .
Mvan_2901|M.vanbaalenii_PYR-1 GLLELAAQWYREQIDISRAQLIEFATALVVTTADITGVLERQLAPPISGD
MAB_3300c|M.abscessus_ATCC_199 GGLDLVTTWFRGELDITRDRLEDFLVALVTR-ANIR---ADQHED--SGE
MSMEG_1355|M.smegmatis_MC2_155 AMAELAQQWLAGNLGDDLDAVVDHALRLVLGR------------------
TH_4000|M.thermoresistible__bu AMAELAQQWLAGNLGDDLDRVVDYALRLVLGR------------------
MAV_3986|M.avium_104 AMAELAQQWLAGHLGGDLDAVVDYASKLVLR-------------------
Mflv_4631|M.gilvum_PYR-GCK GFVELITAWHAGLLDVIQGEIVEHTSRLAETLAERYLVDDAGL-------
MMAR_3142|M.marinum_M GFVEVITAWHSGLLAVTEKEVVAHTSRLAETLAQRYVVSG----------
Mb0848c|M.bovis_AF2122/97 ALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIP
Rv0825c|M.tuberculosis_H37Rv ALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIP
MUL_1200|M.ulcerans_Agy99 GVAQTISAWIEGDVELEPGQLVDQLA-SLLDELSDPRLYGLRGTRAGATA
MLBr_00815|M.leprae_Br4923 ISVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL---------
:
Mvan_2901|M.vanbaalenii_PYR-1 STDDGRS
MAB_3300c|M.abscessus_ATCC_199 AAKPGN-
MSMEG_1355|M.smegmatis_MC2_155 -------
TH_4000|M.thermoresistible__bu -------
MAV_3986|M.avium_104 -------
Mflv_4631|M.gilvum_PYR-GCK -------
MMAR_3142|M.marinum_M -------
Mb0848c|M.bovis_AF2122/97 AGPHN--
Rv0825c|M.tuberculosis_H37Rv AGPHN--
MUL_1200|M.ulcerans_Agy99 ASPAQ--
MLBr_00815|M.leprae_Br4923 -------