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M. thermoresistible (build 8) TH_4000 (-)

annotation: transcriptional regulator, TetR family
coordinates: 3642736 - 3643359
length: 208

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4000--100% (208)transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_1575-7e-2133.16% (196) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_0801fadD272e-2032.85% (207) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0848c-2e-2233.00% (200) hypothetical protein Mb0848c
M. gilvum PYR-GCKMflv_5109-3e-8277.11% (201) TetR family transcriptional regulator
M. tuberculosis H37RvRv0825c-2e-2233.00% (200) hypothetical protein Rv0825c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3300c-6e-2437.25% (204) TetR family transcriptional regulator
M. marinum MMMAR_4855-1e-2435.32% (201) hypothetical protein MMAR_4855
M. avium 104MAV_3986-3e-8477.56% (205) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_1355-2e-9182.61% (207) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_0446-8e-2535.32% (201) hypothetical protein MUL_0446
M. vanbaalenii PYR-1Mvan_1244-3e-8579.31% (203) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


TH_4000|M.thermoresistible__bu      MT--------SPTRWAGVPLTDRRAERRALLIAAAYRLFGEGGEAALSVR
MSMEG_1355|M.smegmatis_MC2_155      MT--------TPTRWAGVPLTDRRAERRALLVDAAFRLFGDGGETALSVR
Mflv_5109|M.gilvum_PYR-GCK          MSGAP-----HATRWAGVPLTDRRAERRALLVDAAFRLFGDGGESAVSVR
Mvan_1244|M.vanbaalenii_PYR-1       MSSAASRPAATPTRWAGVPLTDRRAERRALLVDAAFRLFGDGGEQALSVR
MAV_3986|M.avium_104                MS--------SPSRWAGVPLKDRRAERRALLVEAAYRLFGSEGEAAVSVR
MAB_3300c|M.abscessus_ATCC_199      ---------MPSRTYGGATSGERRARRRAALLDAALDLVAGSGVKGLTVR
Mb0848c|M.bovis_AF2122/97           MQTGQ-----NRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVR
Rv0825c|M.tuberculosis_H37Rv        MQTGQ-----NRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVR
MMAR_4855|M.marinum_M               MQAGQ-----RRGRWTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVR
MUL_0446|M.ulcerans_Agy99           MQAGQ-----RRGRWTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVR
                                                  : *..  .*:* **  *: *.  *..  .  .::**

TH_4000|M.thermoresistible__bu      SVCRESELNSRYFYESFADVDELLGAVYDEVSAQLAAEVETAMAAAVEGA
MSMEG_1355|M.smegmatis_MC2_155      SVCRECGLNTRYFYESFADTDDLIGAVYDEVSALLAADVEAAM-------
Mflv_5109|M.gilvum_PYR-GCK          SVSRECGLNTRYFYESFGGTDDLLGAVYDRVSAELSVAVADAM-------
Mvan_1244|M.vanbaalenii_PYR-1       SVSREAGLNTRYFYESFTDTDDLLGAVYDRVSAELAEVVEAAM-------
MAV_3986|M.avium_104                SVCRECGLNTRYFYESFRDTDDLLGAVYDRVSEQLEEVIAAAI-------
MAB_3300c|M.abscessus_ATCC_199      GVCAEARLNDRYFYESFRSTDELVLAMLDEQMLAGSATIIEAIAK-----
Mb0848c|M.bovis_AF2122/97           AVCRHAGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQ-------
Rv0825c|M.tuberculosis_H37Rv        AVCRHAGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQ-------
MMAR_4855|M.marinum_M               AVCRQAALTERYFYESFSDRDHFVRAVYDDVCTRAMATLMSAN-------
MUL_0446|M.ulcerans_Agy99           AVCRQAALTERYFYESFSDRDHFVRAVYDDVCTRAMATLMSAN-------
                                    .*. .. *. ******* . :.:: *: *         :  *        

TH_4000|M.thermoresistible__bu      GEGAGDSLRARTRAGIVAVLGFSSADPRRGRILFTDARANPVLAARRAAT
MSMEG_1355|M.smegmatis_MC2_155      -EGAGNSLRARTRAGIAAVLGFSSADPRRGRVLFTDARANPVLAQRRAVT
Mflv_5109|M.gilvum_PYR-GCK          -DHAEDSLRARTRAGMAAVLHFSSADPRRGRVLFTDARSNPVLTARRAAT
Mvan_1244|M.vanbaalenii_PYR-1       -SGAGASLPARTRAGMTAVLHFSSADPRRGRVLFTDARANPVLTQRRAAT
MAV_3986|M.avium_104                -EQAGDSLRARTRAGIAAVLGFSSADPRRGRVLFTDARTNPVLAARRRAT
MAB_3300c|M.abscessus_ATCC_199      -SSTSKDPVVRTRAAVGSGLRFLTADPRRGR-LLVESQATEGLAARRRDL
Mb0848c|M.bovis_AF2122/97           ----------TPREAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEW
Rv0825c|M.tuberculosis_H37Rv        ----------TPREAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEW
MMAR_4855|M.marinum_M               ----------TPRDAVERFVALMVDDPVRGRVLLLAPAVEPVLTRSGADW
MUL_0446|M.ulcerans_Agy99           ----------TPRDAVERFVALMVDDPVRGRVLLLAPAVEPVLTRSGADW
                                               .* .:   : :   ** *** *:  .     *:      

TH_4000|M.thermoresistible__bu      QDQLREAVLTEGWRLHPKSDPVAAQVGAAMYTGAMA--ELAQQWLAGNLG
MSMEG_1355|M.smegmatis_MC2_155      QDLLREAVLSEGGRLNPGSDPVAAQVGAAMYTGAMA--ELAQQWLAGNLG
Mflv_5109|M.gilvum_PYR-GCK          QDLLREAVLTEGWRLHPDTDPVAAATGAAMYTGAMA--ELAQQWLSGNLG
Mvan_1244|M.vanbaalenii_PYR-1       QDLLREAVLTEGWRLHPDSDPTAAMVGAAMYTGAMA--ELAQQWLAGHLG
MAV_3986|M.avium_104                QDMLRQGVLSEGWRLNPRSDPVAAEVAAAMYTGAMA--ELAQQWLAGHLG
MAB_3300c|M.abscessus_ATCC_199      VKTLAQVMADQGRVLLPADDALDPDLDLATFTLVSGGLDLVTTWFRGELD
Mb0848c|M.bovis_AF2122/97           MPNFIELLQR---KLSRIVDPVLQKLVATSLIGALT--GLFTAYLNGRLG
Rv0825c|M.tuberculosis_H37Rv        MPNFIELLQR---KLSRIVDPVLQKLVATSLIGALT--GLFTAYLNGRLG
MMAR_4855|M.marinum_M               MPNFIDLLQR---KLSQIADPVLQKLVATSLIGALT--GLFTAYLNGQLG
MUL_0446|M.ulcerans_Agy99           MPNFIDLLQR---KLSQIADPVLQKLVATSLIGALT--GLFTAYLNGQLG
                                       : : :      *    *.       :    .     *   :: *.*.

TH_4000|M.thermoresistible__bu      DDLDRVVDYALRLVLGR-----------------------
MSMEG_1355|M.smegmatis_MC2_155      DDLDAVVDHALRLVLGR-----------------------
Mflv_5109|M.gilvum_PYR-GCK          DDLDVVVDHALRLVLR------------------------
Mvan_1244|M.vanbaalenii_PYR-1       DDLDAVVGYALRLVLR------------------------
MAV_3986|M.avium_104                GDLDAVVDYASKLVLR------------------------
MAB_3300c|M.abscessus_ATCC_199      ITRDRLEDFLVALVTRANIRADQHEDSGEAAKPGN-----
Mb0848c|M.bovis_AF2122/97           ATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN
Rv0825c|M.tuberculosis_H37Rv        ATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN
MMAR_4855|M.marinum_M               ATRQQFIDYCVDLLLGTAAAYAPHRDRGEAERPVAARQHD
MUL_0446|M.ulcerans_Agy99           ATRQQFIDYCVDLLLGTAAAYAPHRDRGEAEHPVAARQHD
                                       . . ..   ::