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MFDVRSRNTRWGGRTGAERRAERRQQLIEAATEIWSESGWAAVTMRGVCARTGLNDRYFYEDFKTREDLL VAAWDGVRNDMLGEVSALFDERVDRPPIETITAAIAIVVDRIARDPGRAHILLAQHVGSSPLQDRRAVAL QEATQLVVEASRPHLREDADETALRMDTLVAVGGFVEVITAWHSGLLAVTEKEVVAHTSRLAETLAQRYV VSG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3142 | - | - | 100% (213) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3144 | - | 1e-19 | 30.89% (191) | AcrR family transcriptional regulator |
| M. marinum M | MMAR_0536 | - | 3e-15 | 27.55% (196) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0848c | - | 6e-14 | 26.00% (200) | hypothetical protein Mb0848c |
| M. gilvum PYR-GCK | Mflv_4631 | - | 3e-96 | 81.73% (208) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0825c | - | 6e-14 | 26.00% (200) | hypothetical protein Rv0825c |
| M. leprae Br4923 | MLBr_00815 | - | 4e-06 | 21.99% (191) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2070c | - | 1e-110 | 94.26% (209) | putative transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 6e-21 | 32.65% (196) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1355 | - | 6e-21 | 32.64% (193) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4000 | - | 2e-18 | 32.50% (200) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1200 | - | 2e-15 | 27.55% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1244 | - | 6e-20 | 31.61% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3142|M.marinum_M -----------------MFDVRSRNTRWGGRTGAERRAERRQQLIEAATE
MAB_2070c|M.abscessus_ATCC_199 --------------------MRSRNKRWGGRTGAERRAERRQQLIEAATE
Mflv_4631|M.gilvum_PYR-GCK -MGADATKVLRPTVVCQDGHVRTRSKRWGGRTGAERRAERRQRLIDAATE
Mb0848c|M.bovis_AF2122/97 ------------------MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQ
Rv0825c|M.tuberculosis_H37Rv ------------------MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQ
MSMEG_1355|M.smegmatis_MC2_155 ---------------------MTTPTRWAGVPLTDRRAERRALLVDAAFR
TH_4000|M.thermoresistible__bu ---------------------MTSPTRWAGVPLTDRRAERRALLIAAAYR
Mvan_1244|M.vanbaalenii_PYR-1 -------------MSSAASRPAATPTRWAGVPLTDRRAERRALLVDAAFR
MAV_3986|M.avium_104 ---------------------MSSPSRWAGVPLKDRRAERRALLVEAAYR
MUL_1200|M.ulcerans_Agy99 ------------------------MRPYRGVEATERLATRRSQLLESGLE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
** *: .
MMAR_3142|M.marinum_M IWSESGW--AAVTMRGVCARTGLNDRYFYEDFKTREDLLVAAWDGVRNDM
MAB_2070c|M.abscessus_ATCC_199 IWSESGW--AAVTMRGVCARTSLNDRYFYEDFKTRDELLVAAWDGVRNDM
Mflv_4631|M.gilvum_PYR-GCK IWSESGW--AAVTMRGVCAKTGLNDRYFYEDFKTRDELLVAAWDGVRNEM
Mb0848c|M.bovis_AF2122/97 LLGGAGG--PALTVRAVCRHAGLTERYFYESFADREHFVRAVYDDVCTRA
Rv0825c|M.tuberculosis_H37Rv LLGGAGG--PALTVRAVCRHAGLTERYFYESFADREHFVRAVYDDVCTRA
MSMEG_1355|M.smegmatis_MC2_155 LFGDGGE--TALSVRSVCRECGLNTRYFYESFADTDDLIGAVYDEVSALL
TH_4000|M.thermoresistible__bu LFGEGGE--AALSVRSVCRESELNSRYFYESFADVDELLGAVYDEVSAQL
Mvan_1244|M.vanbaalenii_PYR-1 LFGDGGE--QALSVRSVSREAGLNTRYFYESFTDTDDLLGAVYDRVSAEL
MAV_3986|M.avium_104 LFGSEGE--AAVSVRSVCRECGLNTRYFYESFRDTDDLLGAVYDRVSEQL
MUL_1200|M.ulcerans_Agy99 LLGSSDRDIAELTVRGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDL
MLBr_00815|M.leprae_Br4923 VFVDHGY--HAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNL
: . : :. . :. :*: * .: .. :
MMAR_3142|M.marinum_M LGEVSALFDER-------VDRPPIETITAAIAIVVDRIARDPGRAHILLA
MAB_2070c|M.abscessus_ATCC_199 LGEVAALFTER-------ANRPPIETITAAIAIVVDGIARDPGRAHILLA
Mflv_4631|M.gilvum_PYR-GCK LGEVSATLAER-------IGQPPMETIRVTIAAVVDRIAEDPGRAKILLA
Mb0848c|M.bovis_AF2122/97 MATLTSAQT-----------------PREAVEQFVELMVDDPVRGRVLLL
Rv0825c|M.tuberculosis_H37Rv MATLTSAQT-----------------PREAVEQFVELMVDDPVRGRVLLL
MSMEG_1355|M.smegmatis_MC2_155 AADVEAAM--------EGAGNSLRARTRAGIAAVLGFSSADPRRGRVLFT
TH_4000|M.thermoresistible__bu AAEVETAMAAAVEGAGEGAGDSLRARTRAGIVAVLGFSSADPRRGRILFT
Mvan_1244|M.vanbaalenii_PYR-1 AEVVEAAMS--------GAGASLPARTRAGMTAVLHFSSADPRRGRVLFT
MAV_3986|M.avium_104 EEVIAAAIE--------QAGDSLRARTRAGIAAVLGFSSADPRRGRVLFT
MUL_1200|M.ulcerans_Agy99 ATTIQAAVAT----------VPPPEQARAGIAEIVRTIVGDARIGRLLFS
MLBr_00815|M.leprae_Br4923 VSSVQQALRTT---------TNNRQRLHAAVQAFFDFIEHDGQGYRLIFE
: : .. * ::::
MMAR_3142|M.marinum_M QHVGSSPLQDRRAVALQEATQLVVEASRPHLREDADETALRMDTLVAVGG
MAB_2070c|M.abscessus_ATCC_199 QHVGSSPLQDRRAVALQEATQLVVEASRPHLRHDADEMALRMDTLIAVGG
Mflv_4631|M.gilvum_PYR-GCK QHVGSSPLQDRRAVALQEATHLVIAASEPHLRPEADETALRMDTLVAVGG
Mb0848c|M.bovis_AF2122/97 APA-VEPALTRSGAEWMPNFIELLQR---KLSRIVDPVLQKLVATSLIGA
Rv0825c|M.tuberculosis_H37Rv APA-VEPALTRSGAEWMPNFIELLQR---KLSRIVDPVLQKLVATSLIGA
MSMEG_1355|M.smegmatis_MC2_155 DAR-ANPVLAQRRAVTQDLLREAVLSEGGRLNPGSDPVAAQVGAAMYTGA
TH_4000|M.thermoresistible__bu DAR-ANPVLAARRAATQDQLREAVLTEGWRLHPKSDPVAAQVGAAMYTGA
Mvan_1244|M.vanbaalenii_PYR-1 DAR-ANPVLTQRRAATQDLLREAVLTEGWRLHPDSDPTAAMVGAAMYTGA
MAV_3986|M.avium_104 DAR-TNPVLAARRRATQDMLRQGVLSEGWRLNPRSDPVAAEVAAAMYTGA
MUL_1200|M.ulcerans_Agy99 THL-ANPVVVRKRTESSALFAMLSGQHAGDALRIPANDRIKVGAHFIVGG
MLBr_00815|M.leprae_Br4923 NDNITEPRVAAQVRVATESCIDAVFALISADSR-LDPHRARMVAVGLVGI
.* : : *
MMAR_3142|M.marinum_M FVEVITAWHSGLLAVTEKEVVAHTSRLAETLAQRYVVSG-----------
MAB_2070c|M.abscessus_ATCC_199 FVEVITAWHSGLLAVTEKEVVAHTSRLAETLAQRYVVSD-----------
Mflv_4631|M.gilvum_PYR-GCK FVELITAWHAGLLDVIQGEIVEHTSRLAETLAERYLVDDAGL--------
Mb0848c|M.bovis_AF2122/97 LTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPA
Rv0825c|M.tuberculosis_H37Rv LTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPA
MSMEG_1355|M.smegmatis_MC2_155 MAELAQQWLAGNLGDDLDAVVDHALRLVLGR-------------------
TH_4000|M.thermoresistible__bu MAELAQQWLAGNLGDDLDRVVDYALRLVLGR-------------------
Mvan_1244|M.vanbaalenii_PYR-1 MAELAQQWLAGHLGDDLDAVVGYALRLVLR--------------------
MAV_3986|M.avium_104 MAELAQQWLAGHLGGDLDAVVDYASKLVLR--------------------
MUL_1200|M.ulcerans_Agy99 VAQTISAWIEGDVELEPGQLVDQLASLLDELSDP-RLYGLRGTRAGATAA
MLBr_00815|M.leprae_Br4923 SVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----------
. : : :
MMAR_3142|M.marinum_M ----
MAB_2070c|M.abscessus_ATCC_199 ----
Mflv_4631|M.gilvum_PYR-GCK ----
Mb0848c|M.bovis_AF2122/97 GPHN
Rv0825c|M.tuberculosis_H37Rv GPHN
MSMEG_1355|M.smegmatis_MC2_155 ----
TH_4000|M.thermoresistible__bu ----
Mvan_1244|M.vanbaalenii_PYR-1 ----
MAV_3986|M.avium_104 ----
MUL_1200|M.ulcerans_Agy99 SPAQ
MLBr_00815|M.leprae_Br4923 ----