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VSSAASRPAATPTRWAGVPLTDRRAERRALLVDAAFRLFGDGGEQALSVRSVSREAGLNTRYFYESFTDT DDLLGAVYDRVSAELAEVVEAAMSGAGASLPARTRAGMTAVLHFSSADPRRGRVLFTDARANPVLTQRRA ATQDLLREAVLTEGWRLHPDSDPTAAMVGAAMYTGAMAELAQQWLAGHLGDDLDAVVGYALRLVLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1244 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5084 | - | 3e-22 | 37.76% (196) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | 9e-19 | 32.40% (179) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 8e-24 | 38.34% (193) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5109 | - | 4e-90 | 86.08% (194) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 4e-23 | 37.82% (193) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-05 | 27.11% (166) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1638 | - | 4e-23 | 31.58% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3144 | - | 1e-22 | 33.51% (191) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 3e-83 | 78.17% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1355 | - | 1e-89 | 86.67% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4000 | - | 2e-85 | 79.31% (203) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1200 | - | 8e-22 | 35.00% (180) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0281c|M.bovis_AF2122/97 --------------MTRSDRPYRGVEAAERLAT------RRRQLLSAGLD
Rv0275c|M.tuberculosis_H37Rv --------------MTRSDRPYRGVEAAERLAT------RRRQSLSAGLD
MUL_1200|M.ulcerans_Agy99 ------------------MRPYRGVEATERLAT------RRSQLLESGLE
MAB_1638|M.abscessus_ATCC_1997 ------------MVTKQATGLYGGRTADERRAE------RRRRLLEAGLE
Mvan_1244|M.vanbaalenii_PYR-1 -------MSSAASRPAATPTRWAGVPLTDRRAE------RRALLVDAAFR
Mflv_5109|M.gilvum_PYR-GCK -------MSGAP-----HATRWAGVPLTDRRAE------RRALLVDAAFR
MSMEG_1355|M.smegmatis_MC2_155 -------MT--------TPTRWAGVPLTDRRAE------RRALLVDAAFR
TH_4000|M.thermoresistible__bu -------MT--------SPTRWAGVPLTDRRAE------RRALLIAAAYR
MAV_3986|M.avium_104 -------MS--------SPSRWAGVPLKDRRAE------RRALLVEAAYR
MMAR_3144|M.marinum_M ---------------MSPARVYGGLSATQRDAQ------RRALLIDAAVA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
. :: : ** : .
Mb0281c|M.bovis_AF2122/97 LLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAEL
Rv0275c|M.tuberculosis_H37Rv LLGSDQHDIAELTIRTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAEL
MUL_1200|M.ulcerans_Agy99 LLGSSDRDIAELTVRGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDL
MAB_1638|M.abscessus_ATCC_1997 VMASSG--WAATTVREICKTAGLNTRYFYECFDGLDELLVAVFDWIIEDS
Mvan_1244|M.vanbaalenii_PYR-1 LFGDGGE--QALSVRSVSREAGLNTRYFYESFTDTDDLLGAVYDRVSAEL
Mflv_5109|M.gilvum_PYR-GCK LFGDGGE--SAVSVRSVSRECGLNTRYFYESFGGTDDLLGAVYDRVSAEL
MSMEG_1355|M.smegmatis_MC2_155 LFGDGGE--TALSVRSVCRECGLNTRYFYESFADTDDLIGAVYDEVSALL
TH_4000|M.thermoresistible__bu LFGEGGE--AALSVRSVCRESELNSRYFYESFADVDELLGAVYDEVSAQL
MAV_3986|M.avium_104 LFGSEGE--AAVSVRSVCRECGLNTRYFYESFRDTDDLLGAVYDRVSEQL
MMAR_3144|M.marinum_M LMGKQGA--AACTVTAVCTESGVTSRYFYQQFRDRDALLRAMFTKISTTF
MLBr_00815|M.leprae_Br4923 VFVDHGY--HAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNL
:: . : :. . :. :*: * . : :
Mb0281c|M.bovis_AF2122/97 VATTQAAV--------TAVP--AREQTRAGMANIVRTITADARVGRLLFS
Rv0275c|M.tuberculosis_H37Rv VATTQAAV--------TAVP--AREQTRAGMANIVRTITADARVGRLLFS
MUL_1200|M.ulcerans_Agy99 ATTIQAAV--------ATVP--PPEQARAGIAEIVRTIVGDARIGRLLFS
MAB_1638|M.abscessus_ATCC_1997 IATAGSAM--------AAADKDSRSQVHAGVVGAVTALTADPRRARVIAT
Mvan_1244|M.vanbaalenii_PYR-1 AEVVEAAM--------SGAGASLPARTRAGMTAVLHFSSADPRRGRVLFT
Mflv_5109|M.gilvum_PYR-GCK SVAVADAM--------DHAEDSLRARTRAGMAAVLHFSSADPRRGRVLFT
MSMEG_1355|M.smegmatis_MC2_155 AADVEAAM--------EGAGNSLRARTRAGIAAVLGFSSADPRRGRVLFT
TH_4000|M.thermoresistible__bu AAEVETAMAAAVEGAGEGAGDSLRARTRAGIVAVLGFSSADPRRGRILFT
MAV_3986|M.avium_104 EEVIAAAI--------EQAGDSLRARTRAGIAAVLGFSSADPRRGRVLFT
MMAR_3144|M.marinum_M QAVITKAIP--------DDTVAPQELAYAPIKALVQMIENDPSMARILFV
MLBr_00815|M.leprae_Br4923 VSSVQQALR---------TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFE
*: * : . * *::
Mb0281c|M.bovis_AF2122/97 TQLANA--VITRKRAESSALFAMLSGQHA--VDTLHAPANDHVKAVAHFA
Rv0275c|M.tuberculosis_H37Rv TQLANA--VITRKRAESSALFAMLSGQHA--VDTLHAPANDHVKAVAHFA
MUL_1200|M.ulcerans_Agy99 THLANP--VVVRKRTESSALFAMLSGQHA--GDALRIPANDRIKVGAHFI
MAB_1638|M.abscessus_ATCC_1997 EAMGSQ--RLTRRRMRLTHYMALMLGAAR--AEFDPEADPNYTAVQAEAL
Mvan_1244|M.vanbaalenii_PYR-1 DARANP--VLTQRRAATQDLLREAVLTEG--WRLHPDSDPTAAMVGAAMY
Mflv_5109|M.gilvum_PYR-GCK DARSNP--VLTARRAATQDLLREAVLTEG--WRLHPDTDPVAAATGAAMY
MSMEG_1355|M.smegmatis_MC2_155 DARANP--VLAQRRAVTQDLLREAVLSEG--GRLNPGSDPVAAQVGAAMY
TH_4000|M.thermoresistible__bu DARANP--VLAARRAATQDQLREAVLTEG--WRLHPKSDPVAAQVGAAMY
MAV_3986|M.avium_104 DARTNP--VLAARRRATQDMLRQGVLSEG--WRLNPRSDPVAAEVAAAMY
MMAR_3144|M.marinum_M ESGAEP--LLRQLRSELMSEFAELVLREARLHLDIPSEVIQVADLAATYG
MLBr_00815|M.leprae_Br4923 NDNITEPRVAAQVRVATESCIDAVFALIS----ADSRLDPHRARMVAVGL
* : *
Mb0281c|M.bovis_AF2122/97 VGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAK
Rv0275c|M.tuberculosis_H37Rv VGGVGQTISAWLAGDVRLDPDQLVDQLAALLDELTDPNLSRPRVAATAAK
MUL_1200|M.ulcerans_Agy99 VGGVAQTISAWIEGDVELEPGQLVDQLASLLDELSDPRLYGLR----GTR
MAB_1638|M.abscessus_ATCC_1997 AAGVAGTVLAWLDGRLRLEREELAEYTAQFVDQAMFTPLPVHN----SVE
Mvan_1244|M.vanbaalenii_PYR-1 TGAMAELAQQWLAGHLGDDLDAVVGYALRLVLR-----------------
Mflv_5109|M.gilvum_PYR-GCK TGAMAELAQQWLSGNLGDDLDVVVDHALRLVLR-----------------
MSMEG_1355|M.smegmatis_MC2_155 TGAMAELAQQWLAGNLGDDLDAVVDHALRLVLGR----------------
TH_4000|M.thermoresistible__bu TGAMAELAQQWLAGNLGDDLDRVVDYALRLVLGR----------------
MAV_3986|M.avium_104 TGAMAELAQQWLAGHLGGDLDAVVDYASKLVLR-----------------
MMAR_3144|M.marinum_M VGGLFEILRRWIDGQLNLSTEVLIEHCAGFLGSLGLYTLGQKPDPAASHI
MLBr_00815|M.leprae_Br4923 VGISVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL-------
.. *: . :
Mb0281c|M.bovis_AF2122/97 SGANDPQPPEVAGQPPSSARPARRS
Rv0275c|M.tuberculosis_H37Rv SGANDPQPPEVAGQPPSSARPARRS
MUL_1200|M.ulcerans_Agy99 AGATAASPAQ---------------
MAB_1638|M.abscessus_ATCC_1997 H------------------------
Mvan_1244|M.vanbaalenii_PYR-1 -------------------------
Mflv_5109|M.gilvum_PYR-GCK -------------------------
MSMEG_1355|M.smegmatis_MC2_155 -------------------------
TH_4000|M.thermoresistible__bu -------------------------
MAV_3986|M.avium_104 -------------------------
MMAR_3144|M.marinum_M QVDINSPAGHNR-------------
MLBr_00815|M.leprae_Br4923 -------------------------