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SAEERHRNRRTRLIEAATELIGTRGVAAATVTAVCAESGVTSRYFYQHFSGRDALLRAVYQQLYATFQEV IVDAIPDAGEPPEVLAYAPIRRLVSMIDNDPRLGRILFVESATEPLLRELRSELMAGFTDLVLREARLHL DIADSAVGVAHLASTLGVGGLFEVLRRRLDGELEFTTDELVQHCAGFLGSLGNYVLLQNTDQSATTEARP HR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0313 | - | - | 100% (213) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5084 | - | 5e-19 | 30.85% (188) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1244 | - | 9e-19 | 32.40% (179) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0848c | - | 4e-19 | 30.65% (186) | hypothetical protein Mb0848c |
| M. gilvum PYR-GCK | Mflv_4630 | - | 1e-106 | 91.94% (211) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0825c | - | 4e-19 | 30.65% (186) | hypothetical protein Rv0825c |
| M. leprae Br4923 | MLBr_00949 | - | 4e-05 | 34.62% (52) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_2068c | - | 6e-63 | 63.49% (189) | putative transcriptional regulator |
| M. marinum M | MMAR_3144 | - | 9e-68 | 62.14% (206) | AcrR family transcriptional regulator |
| M. avium 104 | MAV_3986 | - | 2e-21 | 34.24% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5768 | - | 3e-20 | 34.38% (192) | hypothetical protein MSMEG_5768 |
| M. thermoresistible (build 8) | TH_1575 | - | 4e-21 | 32.97% (185) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0446 | - | 9e-21 | 32.26% (186) | hypothetical protein MUL_0446 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0313|M.vanbaalenii_PYR-1 ------------MSAEERHRNRRTRLIEAATELIGTRGVAAATVTAVCAE
Mflv_4630|M.gilvum_PYR-GCK ------------MSAEERHRNRRTRLIEAAMELIGTHGVAAATVTAVCAE
MAB_2068c|M.abscessus_ATCC_199 ---------------------------------MGTHGATACTVTAVCAK
MMAR_3144|M.marinum_M ---MSPARVYGGLSATQRDAQRRALLIDAAVALMGKQGAAACTVTAVCTE
MSMEG_5768|M.smegmatis_MC2_155 MPSGQRRGRWSGVPLRERTALRRDELIAAGVKLLGAADGPALTVRAVCRE
TH_1575|M.thermoresistible__bu ------------VPLSDRQTLRREELIAAGVKLLGHREGPALTVRAVCRE
Mb0848c|M.bovis_AF2122/97 MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRH
Rv0825c|M.tuberculosis_H37Rv MQTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRH
MUL_0446|M.ulcerans_Agy99 MQAGQRRGRWTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCRQ
MAV_3986|M.avium_104 ---MSSPSRWAGVPLKDRRAERRALLVEAAYRLFGSEGEAAVSVRSVCRE
MLBr_00949|M.leprae_Br4923 ------MTTSARTHRWAKTGAIQRRILDAAIEVFATRSFTTATMTDAMTG
:. .: :: .
Mvan_0313|M.vanbaalenii_PYR-1 SGVTSRYFYQHFSGRDALLRAVYQQLYATFQEVIVDAIPDAGEPPEVLAY
Mflv_4630|M.gilvum_PYR-GCK SGVTSRYFYQHFPDRDALLRAVYQQLYATFQEVIVDAIPDAGAPPEVLAY
MAB_2068c|M.abscessus_ATCC_199 SGVTSRYFYQQFRDRDALLRAVFAKISATFQAVITSAIPDDTVAPQELAY
MMAR_3144|M.marinum_M SGVTSRYFYQQFRDRDALLRAMFTKISTTFQAVITKAIPDDTVAPQELAY
MSMEG_5768|M.smegmatis_MC2_155 AGLTERYFYECFNDRDGFVRAVYDDVCATAMSALTAADTPR---------
TH_1575|M.thermoresistible__bu AGLTERYFYESFADRDEFVRAVYDDVCARAMSTLMTADTPR---------
Mb0848c|M.bovis_AF2122/97 AGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPR---------
Rv0825c|M.tuberculosis_H37Rv AGLTERYFYESFADREHFVRAVYDDVCTRAMATLTSAQTPR---------
MUL_0446|M.ulcerans_Agy99 AALTERYFYESFSDRDHFVRAVYDDVCTRAMATLMSANTPR---------
MAV_3986|M.avium_104 CGLNTRYFYESFRDTDDLLGAVYDRVSEQLEEVIAAAIEQAGDSLRARTR
MLBr_00949|M.leprae_Br4923 SGAIIGSIYHHFGGKRKLFLAIFEQMGRQRRPPHRRGDATS---------
.. :*. * . :. *:: : .
Mvan_0313|M.vanbaalenii_PYR-1 APIRRLVSMIDNDPRLGRILFVESATEPLLRELRSELMAGFTDLVLREAR
Mflv_4630|M.gilvum_PYR-GCK APIRGLVSMINNDPRLGRILFVESATEPLLRELRSDMMTGFTDLVLREAR
MAB_2068c|M.abscessus_ATCC_199 APIKALVQLIENDPRMARILFVESGAESLLRQLRSELMTDFAELVLREAR
MMAR_3144|M.marinum_M APIKALVQMIENDPSMARILFVESGAEPLLRQLRSELMSEFAELVLREAR
MSMEG_5768|M.smegmatis_MC2_155 KAVEQFVSLMVDDPTRGRVLLLAPESEPVLTRSGAEWMPNFIDLLQRKLT
TH_1575|M.thermoresistible__bu DAVERFVALMVDDPVRGRVLLLAPEVEPVLTRSGAKWMPNFIDLLQRKLT
Mb0848c|M.bovis_AF2122/97 EAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLS
Rv0825c|M.tuberculosis_H37Rv EAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLS
MUL_0446|M.ulcerans_Agy99 DAVERFVALMVDDPVRGRVLLLAPAVEPVLTRSGADWMPNFIDLLQRKLS
MAV_3986|M.avium_104 AGIAAVLGFSSADPRRGRVLFTDARTNPVLAARRRATQDMLRQGVLSEGW
MLBr_00949|M.leprae_Br4923 -------GPIRPSGDRSAAGIRSPRTGPTSRRCG----------------
. . : . .
Mvan_0313|M.vanbaalenii_PYR-1 LHLDIADSAVGVAHLASTLGVGGLFEVLRRRLDGELEFTTDELVQHCAG-
Mflv_4630|M.gilvum_PYR-GCK LHLDIADSAVGVAHLASTLGVGGLFEVLRRWLDGELEFTTDELVQHCAG-
MAB_2068c|M.abscessus_ATCC_199 LHLDIPSDVLQVADLAATYGVGGLFEILRRWIDGQLNLSTEMLIEHCAG-
MMAR_3144|M.marinum_M LHLDIPSEVIQVADLAATYGVGGLFEILRRWIDGQLNLSTEVLIEHCAG-
MSMEG_5768|M.smegmatis_MC2_155 RIADP-----VRQAMVATSLIGALTALFTAYLNDRLPATREQFIDFCVDM
TH_1575|M.thermoresistible__bu RITDP-----ALQAMVATGLIGALTALFTAYLDGRLAATREQFIDYCVGI
Mb0848c|M.bovis_AF2122/97 RIVDP-----VLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNM
Rv0825c|M.tuberculosis_H37Rv RIVDP-----VLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNM
MUL_0446|M.ulcerans_Agy99 QIADP-----VLQKLVATSLIGALTGLFTAYLNGQLGATRQQFIDYCVDL
MAV_3986|M.avium_104 RLNPRSDP--VAAEVAAAMYTGAMAELAQQWLAGHLGGDLDAVVDYASKL
MLBr_00949|M.leprae_Br4923 -------------------KTGTRPGCCRP--ETHLQASRSPVATA----
* .* . .
Mvan_0313|M.vanbaalenii_PYR-1 FLGSLGNYVLLQNTDQSATTEARPHR-------
Mflv_4630|M.gilvum_PYR-GCK FLGSLGSYVLLQNAVESATTKAKPQS-------
MAB_2068c|M.abscessus_ATCC_199 FLGILGLYTLGQAPDQAAPPLAKAEETR-----
MMAR_3144|M.marinum_M FLGSLGLYTLGQKPDPAASHIQVDINSPAGHNR
MSMEG_5768|M.smegmatis_MC2_155 LLGRVGSF-------------------------
TH_1575|M.thermoresistible__bu LLNPVASY-------------------------
Mb0848c|M.bovis_AF2122/97 LLSTAATYAPHRERGESEHSIPAGPHN------
Rv0825c|M.tuberculosis_H37Rv LLSTAATYAPHRERGESEHSIPAGPHN------
MUL_0446|M.ulcerans_Agy99 LLGTAAAYAPHRDRGEAEHPVAARQHD------
MAV_3986|M.avium_104 VLR------------------------------
MLBr_00949|M.leprae_Br4923 ---------------------------------