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QTGQNRGRWSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCRHAGLTERYFYESFADREHFVRA VYDDVCTRAMATLTSAQTPREAVEQFVELMVDDPVRGRVLLLAPAVEPALTRSGAEWMPNFIELLQRKLS RIVDPVLQKLVATSLIGALTGLFTAYLNGRLGATRKQFIDYCVNMLLSTAATYAPHRERGESEHSIPAGP HN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0825c | - | - | 100% (213) | hypothetical protein Rv0825c |
| M. tuberculosis H37Rv | Rv0275c | - | 1e-15 | 32.63% (190) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 4e-06 | 34.51% (113) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0848c | - | 1e-121 | 100.00% (213) | hypothetical protein Mb0848c |
| M. gilvum PYR-GCK | Mflv_1669 | - | 1e-75 | 69.95% (193) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02677 | - | 9e-05 | 30.36% (112) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0756c | - | 9e-54 | 56.48% (193) | hypothetical protein MAB_0756c |
| M. marinum M | MMAR_4855 | - | 1e-99 | 81.69% (213) | hypothetical protein MMAR_4855 |
| M. avium 104 | MAV_0773 | - | 7e-86 | 81.77% (192) | hypothetical protein MAV_0773 |
| M. smegmatis MC2 155 | MSMEG_5768 | - | 1e-81 | 76.29% (194) | hypothetical protein MSMEG_5768 |
| M. thermoresistible (build 8) | TH_1575 | - | 1e-77 | 76.92% (182) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0446 | - | 1e-100 | 82.16% (213) | hypothetical protein MUL_0446 |
| M. vanbaalenii PYR-1 | Mvan_5084 | - | 8e-76 | 69.43% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0825c|M.tuberculosis_H37Rv MQTGQNRGR-WSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCR
Mb0848c|M.bovis_AF2122/97 MQTGQNRGR-WSGVPLESRHALRRDNLVAAGVQLLGGAGGPALTVRAVCR
MAV_0773|M.avium_104 -------------MPLESRLALRRDNLINAGVQLLGGSGGPALTVRAVCR
MMAR_4855|M.marinum_M MQAGQRRGR-WTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCR
MUL_0446|M.ulcerans_Agy99 MQAGQRRGR-WTGVPLEDRHAVRRDTLIAAGVQLLGEEAGPALTVRAVCR
MSMEG_5768|M.smegmatis_MC2_155 MPSGQRRGR-WSGVPLRERTALRRDELIAAGVKLLGAADGPALTVRAVCR
TH_1575|M.thermoresistible__bu -------------VPLSDRQTLRREELIAAGVKLLGHREGPALTVRAVCR
Mflv_1669|M.gilvum_PYR-GCK MPSGQRRGR-WSGVPLQDRQALRRDELITAGIGLLGSSGGPNLTVRAVCK
Mvan_5084|M.vanbaalenii_PYR-1 MPSGQRRGR-WSGVPLQDRQALRRDELITAGISLLGSPGGPHLTVRAVCK
MAB_0756c|M.abscessus_ATCC_199 MANGQAQRRSWAGVSPAERADERRRELMAAGVRLLGLRPRPAVTVRAVCR
MLBr_02677|M.leprae_Br4923 -MESQRRTQ-------EERSTATRDALTLARHRLWRLRGYAEVGTPEIAK
.* * * * * . : . :.:
Rv0825c|M.tuberculosis_H37Rv HAGLTERYFYESFADREHFVRAVYDDVCTRAMATLT----------SAQT
Mb0848c|M.bovis_AF2122/97 HAGLTERYFYESFADREHFVRAVYDDVCTRAMATLT----------SAQT
MAV_0773|M.avium_104 KAALTERYFYESFTDRDEFVRAVYDDVCTRAMNTLT----------SATT
MMAR_4855|M.marinum_M QAALTERYFYESFSDRDHFVRAVYDDVCTRAMATLM----------SANT
MUL_0446|M.ulcerans_Agy99 QAALTERYFYESFSDRDHFVRAVYDDVCTRAMATLM----------SANT
MSMEG_5768|M.smegmatis_MC2_155 EAGLTERYFYECFNDRDGFVRAVYDDVCATAMSALT----------AADT
TH_1575|M.thermoresistible__bu EAGLTERYFYESFADRDEFVRAVYDDVCARAMSTLM----------TADT
Mflv_1669|M.gilvum_PYR-GCK AAGLTERYFYESFTDRDEYVAAVYDDVCTAAMATLR----------ESES
Mvan_5084|M.vanbaalenii_PYR-1 AAGLTERYFYESFTDRDEYVAAVYDNVCTAAMSTLM----------KSDS
MAB_0756c|M.abscessus_ATCC_199 SAGMTERYFYEHFSDRDTFVRAVYDHVGFRAIEALS----------GVRS
MLBr_02677|M.leprae_Br4923 EADTTRGAVYHQFTDKAALFRDVVETVEQDAMAQIASVVASSGAKTPVDA
* *. .*. * *: . * : * *: : :
Rv0825c|M.tuberculosis_H37Rv PREAVEQFVELMVDDPVRGRVLLLAPAVE-----PALTRSGAEWMPNFIE
Mb0848c|M.bovis_AF2122/97 PREAVEQFVELMVDDPVRGRVLLLAPAVE-----PALTRSGAEWMPNFIE
MAV_0773|M.avium_104 PREAVERFVELMVDDPVRGRVLLLAPAVE-----PVLTRSGAEWMPNFID
MMAR_4855|M.marinum_M PRDAVERFVALMVDDPVRGRVLLLAPAVE-----PVLTRSGADWMPNFID
MUL_0446|M.ulcerans_Agy99 PRDAVERFVALMVDDPVRGRVLLLAPAVE-----PVLTRSGADWMPNFID
MSMEG_5768|M.smegmatis_MC2_155 PRKAVEQFVSLMVDDPTRGRVLLLAPESE-----PVLTRSGAEWMPNFID
TH_1575|M.thermoresistible__bu PRDAVERFVALMVDDPVRGRVLLLAPEVE-----PVLTRSGAKWMPNFID
Mflv_1669|M.gilvum_PYR-GCK MRDAVERFVALMIDDPARGRVLLLAPEAE-----PVLARSGARWMPNFIE
Mvan_5084|M.vanbaalenii_PYR-1 MRDAVERFVALMIDDPARGRVLLLAPEVE-----PVLARSGARWMPNFID
MAB_0756c|M.abscessus_ATCC_199 AYEGVDAFARLMVDEPTMGRVLLIAPTFE-----PTLSESGYDWLPRFVA
MLBr_02677|M.leprae_Br4923 IRAKVDAWLEGLADPQVRQLILLYAPSVLGWAAFRDVAQHYSLGMTEQQL
*: : : * . :** ** ::. :..
Rv0825c|M.tuberculosis_H37Rv LLQRKLSR-IVDPVLQKLVATSLIGALTGLFTAYLNGRLGATRKQ-----
Mb0848c|M.bovis_AF2122/97 LLQRKLSR-IVDPVLQKLVATSLIGALTGLFTAYLNGRLGATRKQ-----
MAV_0773|M.avium_104 LLQRKLSR-IGDAVLQKMIATSLVGGLSSLFTAYLHGQLGATRKQ-----
MMAR_4855|M.marinum_M LLQRKLSQ-IADPVLQKLVATSLIGALTGLFTAYLNGQLGATRQQ-----
MUL_0446|M.ulcerans_Agy99 LLQRKLSQ-IADPVLQKLVATSLIGALTGLFTAYLNGQLGATRQQ-----
MSMEG_5768|M.smegmatis_MC2_155 LLQRKLTR-IADPVRQAMVATSLIGALTALFTAYLNDRLPATREQ-----
TH_1575|M.thermoresistible__bu LLQRKLTR-ITDPALQAMVATGLIGALTALFTAYLDGRLAATREQ-----
Mflv_1669|M.gilvum_PYR-GCK LLQHNLTR-ITDTTTQAMVATGLIGALTALFTAYLDGRLEATREQ-----
Mvan_5084|M.vanbaalenii_PYR-1 LLQRNLTQ-ISDPTTQAMVATGLIGALTALFTAYLDGRLGATRER-----
MAB_0756c|M.abscessus_ATCC_199 LLQGKLSTNLADEVQQQLVATSLVGALTSLFTAYLNEELNVDRQR-----
MLBr_02677|M.leprae_Br4923 LSEASRARQLAQPLDHVLIGKLYESAMAIRRHHRLPEASPARNQTGAAPT
* : . : : : : ::.. ..:: * . .:
Rv0825c|M.tuberculosis_H37Rv FIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN---------
Mb0848c|M.bovis_AF2122/97 FIDYCVNMLLSTAATYAPHRERGESEHSIPAGPHN---------
MAV_0773|M.avium_104 FIDYCTNMLYITAAPYVSAGELGKSQ------------------
MMAR_4855|M.marinum_M FIDYCVDLLLGTAAAYAPHRDRGEAERPVAARQHD---------
MUL_0446|M.ulcerans_Agy99 FIDYCVDLLLGTAAAYAPHRDRGEAEHPVAARQHD---------
MSMEG_5768|M.smegmatis_MC2_155 FIDFCVDMLLGRVGSF----------------------------
TH_1575|M.thermoresistible__bu FIDYCVGILLNPVASY----------------------------
Mflv_1669|M.gilvum_PYR-GCK FIDHCAELLLSRAVT-----------------------------
Mvan_5084|M.vanbaalenii_PYR-1 FIDHCAELLLSRAVT-----------------------------
MAB_0756c|M.abscessus_ATCC_199 FVDYCVQILLQGANASVTPRPTSPSPQQPS--------------
MLBr_02677|M.leprae_Br4923 HREHVARPSCEALTRHIRHRSTRTRSHRGKRGELLPRAATSSLL
. :. .