For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTVRGICRQAGLSARYFYESFPDKDEFIGGVFDW VVGDLATTIQAAVATVPPPEQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSGQ HAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLASLLDELSDPRLYGLRGTRAGA TAASPAQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1200 | - | - | 100% (218) | TetR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_0446 | - | 8e-17 | 31.44% (194) | hypothetical protein MUL_0446 |
| M. ulcerans Agy99 | MUL_3848 | - | 7e-05 | 30.56% (72) | putative transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 5e-81 | 71.36% (213) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0331 | - | 6e-70 | 64.36% (202) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 2e-80 | 70.89% (213) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 3e-06 | 35.19% (108) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2494c | - | 4e-48 | 46.88% (192) | putative transcriptional regulator |
| M. marinum M | MMAR_0536 | - | 1e-119 | 99.54% (218) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4882 | - | 3e-83 | 74.13% (201) | FadD27 protein |
| M. smegmatis MC2 155 | MSMEG_0612 | - | 3e-62 | 59.09% (198) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 4e-72 | 62.87% (202) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. vanbaalenii PYR-1 | Mvan_0409 | - | 2e-58 | 65.64% (163) | FadD27 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1200|M.ulcerans_Agy99 ----------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTV
MMAR_0536|M.marinum_M ----------MRPYRGVEATERLAARRSQLLESGLELLGSSDRDIAELTV
Mb0281c|M.bovis_AF2122/97 ----MTRSD--RPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
Rv0275c|M.tuberculosis_H37Rv ----MTRSD--RPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTI
MAV_4882|M.avium_104 -MVCMSQTSGARPYRGVEAAERLATRRNRLLGAGLDLLGAEQQNIAAVTV
Mflv_0331|M.gilvum_PYR-GCK MGCMA----QVRPYRGVDAPARVAERRRRLLEAGLDLLGG-QLNPPELTV
Mvan_0409|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_0801|M.thermoresistible__bu MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAELTV
MSMEG_0612|M.smegmatis_MC2_155 -------MTPVRPYRGIEAADRLAQRRGQLLAAGLDLLGD---ENAEVTV
MAB_2494c|M.abscessus_ATCC_199 -----MSSPAGRSYSGLPADERLARRRQRLLEVGLDILGTPD-GSGDLTL
MLBr_00717|M.leprae_Br4923 ---------MTTARRRLSPED----RRAELLALGAEVFGK--RPYDEVRI
:
MUL_1200|M.ulcerans_Agy99 RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVAT-VPP
MMAR_0536|M.marinum_M RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVAT-VPP
Mb0281c|M.bovis_AF2122/97 RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTA-VPA
Rv0275c|M.tuberculosis_H37Rv RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTA-VPA
MAV_4882|M.avium_104 RGVCRRAGLAARYFYESFTDKDQFVACVFDWVVAELAATTQAAVTA-VPA
Mflv_0331|M.gilvum_PYR-GCK RAICAQSGLAARYFYESFTDKDVFVGAVFDRVIADIATTTQAAVAA-APP
Mvan_0409|M.vanbaalenii_PYR-1 RAICAQSGLAARYFYESFADKDVFVGAVFDWVVADIAATTQAAVAA-APV
TH_0801|M.thermoresistible__bu RAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAA-APR
MSMEG_0612|M.smegmatis_MC2_155 RAVCQRAGLAARYFYESFGDKDAFVSEVYDWVIAEIAASTQAAVAS-VPL
MAB_2494c|M.abscessus_ATCC_199 RTVCQRSGLAQRYFYESFADKDEYAAAIFDWAIEGLAATVEAEVAA-AHP
MLBr_00717|M.leprae_Br4923 DEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNIPPPAGLTM
:. .:*:: :*. * ** : . : . : :: : .:
MUL_1200|M.ulcerans_Agy99 PEQARAGIAEIVRTIVGDARIGRLLFS-THLANPVVVRKRTESSALFAML
MMAR_0536|M.marinum_M PEQARAGIAEIVRTIVGDARIGRLLFS-THLANPVVVRKRTESSALFAML
Mb0281c|M.bovis_AF2122/97 REQTRAGMANIVRTITADARVGRLLFS-TQLANAVITRKRAESSALFAML
Rv0275c|M.tuberculosis_H37Rv REQTRAGMANIVRTITADARVGRLLFS-TQLANAVITRKRAESSALFAML
MAV_4882|M.avium_104 HEQTRAGMANIVRTITEDARVGRLLFS-TQLADPVVVRKRAESSALFAML
Mflv_0331|M.gilvum_PYR-GCK REQSRQGMANIVRAISEDARVGRLLFN-AHLDNPVVVRKRAESGALFALL
Mvan_0409|M.vanbaalenii_PYR-1 REQSRQGMANIVNTISDDIRVGRLLFN-TRLDNPVVVRKRAESGALFALL
TH_0801|M.thermoresistible__bu RDQTRAGMANIVRTVSEDPRVGRLLFS-RHLSTATVVRKRAESGALFAML
MSMEG_0612|M.smegmatis_MC2_155 AEQTTAAMTNIVRTIADDPRIGRLLFS-AKLSNEVVVRKRVEGIGFFAGL
MAB_2494c|M.abscessus_ATCC_199 RLQVRAGITSVVRAVSADRRIGQLLYS-RHQVNPVLVRRRFDATAMFVSL
MLBr_00717|M.leprae_Br4923 FEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEH
: .: : : . . : .: :.
MUL_1200|M.ulcerans_Agy99 SGQHAGDALRIPANDRIKVGAHFIVGGVAQ---TISAWIEGDVELEPGQL
MMAR_0536|M.marinum_M SGQHAGDALRIPANDRIKVGAHFIVGGVAQ---TISAWIEGDVELEPGQL
Mb0281c|M.bovis_AF2122/97 SGQHAVDTLHAPANDHVKAVAHFAVGGVGQ---TISAWLAGDVRLDPDQL
Rv0275c|M.tuberculosis_H37Rv SGQHAVDTLHAPANDHVKAVAHFAVGGVGQ---TISAWLAGDVRLDPDQL
MAV_4882|M.avium_104 SGQHVGDALRMPANDRIKAAAHFVVGGVAQ---TISAWLAGEVRLEPDQL
Mflv_0331|M.gilvum_PYR-GCK SGQHAGSALRLERNDRITSAAHFVVGGVAQ---TLSAWLAGDLTFTEAQL
Mvan_0409|M.vanbaalenii_PYR-1 SGQHAGTALQVEPNERIRAAAHFAVGGVAQ---TLSAWLAGDLAFTPEQL
TH_0801|M.thermoresistible__bu SGQHVGSTMQLPENERIKATSHFVVGGVGQ---TIGAWLAGEVRLSPEAL
MSMEG_0612|M.smegmatis_MC2_155 LGQHTVDALRLPENDQLRATAHFAVGGVTQ---TISAWLGGEVSFTPDEL
MAB_2494c|M.abscessus_ATCC_199 FAQHLHDWFRRDDQGNLPVLAHFIVGGVGQ---AVTAWLHQEVTISEDEL
MLBr_00717|M.leprae_Br4923 IMSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCRQRIMDPSTD
.: . : .: . : : : :. : : :
MUL_1200|M.ulcerans_Agy99 VDQLAS-----LLDELSDPRLYGLRGTRAGATAASPAQ------------
MMAR_0536|M.marinum_M VDQLAS-----LLDELSDPRLYGLRGTRAGATAASPAQ------------
Mb0281c|M.bovis_AF2122/97 VDQLAA-----LLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSS
Rv0275c|M.tuberculosis_H37Rv VDQLAA-----LLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSS
MAV_4882|M.avium_104 VDQLAA-----LLDELAEPALYRR--TETPAQS-----------------
Mflv_0331|M.gilvum_PYR-GCK AAQLGA-----LIDQLADPALYRD--------------------------
Mvan_0409|M.vanbaalenii_PYR-1 AGQLGA-----LLDQLADPTLYRD--------------------------
TH_0801|M.thermoresistible__bu IDQLAS-----VIDQLAKPELFRAD-------------------------
MSMEG_0612|M.smegmatis_MC2_155 VQQLRS-----LLDALANLQSRK---------------------------
MAB_2494c|M.abscessus_ATCC_199 IEQLVD-----MLLAHGPAGSGQR--------------------------
MLBr_00717|M.leprae_Br4923 ADRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ------------
:* ::
MUL_1200|M.ulcerans_Agy99 -------
MMAR_0536|M.marinum_M -------
Mb0281c|M.bovis_AF2122/97 ARPARRS
Rv0275c|M.tuberculosis_H37Rv ARPARRS
MAV_4882|M.avium_104 -------
Mflv_0331|M.gilvum_PYR-GCK -------
Mvan_0409|M.vanbaalenii_PYR-1 -------
TH_0801|M.thermoresistible__bu -------
MSMEG_0612|M.smegmatis_MC2_155 -------
MAB_2494c|M.abscessus_ATCC_199 -------
MLBr_00717|M.leprae_Br4923 -------