For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VRVLTVDAAPLAARPDLVGSSDLPAHARIAQWLEALIASGDLIPGDKLPPEVEIATSLGVSRMTLRQALS AVEAKGLIDRRRGRFGGNFVAAPRFEFDHASLPGFTEQMRRFEVEAGAQVLMATTGRPDAEVSRALGLRR TDQVHRILRARTANGEPIVLEEAYLPAAVFPGMLSKNLQASLYALMRGYGHAPCAADERIEATSATPEQA RVLGVEPSCPLLLVVRTSFADNGVAVEFSRDYHRSDRTTIRIQSRADPVRQGY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | - | 100% (263) | UbiC transcription regulator-associated domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | 2e-35 | 39.25% (214) | UbiC transcription regulator-associated domain-containing |
| M. vanbaalenii PYR-1 | Mvan_4015 | - | 2e-30 | 36.91% (233) | UbiC transcription regulator-associated domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 2e-20 | 32.13% (249) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1234 | - | 1e-37 | 40.85% (213) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 2e-20 | 32.13% (249) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 8e-26 | 33.62% (229) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4842 | - | 2e-22 | 30.80% (237) | regulatory protein |
| M. avium 104 | MAV_1744 | - | 6e-17 | 30.56% (216) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0268 | - | 2e-36 | 39.91% (213) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_4115 | - | 3e-12 | 34.39% (189) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0525 | - | 3e-23 | 31.47% (232) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1234|M.gilvum_PYR-GCK ---------MVEPIWRRRGGPVPTQTEDLRRRIVADINAGK--PGTKLGS
MSMEG_0268|M.smegmatis_MC2_155 ---------------------MPVQSEELRRRLVADINAGT--PGAKLGS
MAB_0953|M.abscessus_ATCC_1997 ---------MEE-------SEGGPVAEDVRRRILSMLAQGTLHPGSRLGS
Mvan_2288|M.vanbaalenii_PYR-1 MRVLTVDAAPLAARPDLVGSSDLPAHARIAQWLEALIASGDLIPGDKLPP
Mb0816c|M.bovis_AF2122/97 ---MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPS
Rv0792c|M.tuberculosis_H37Rv ---MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPS
MMAR_4842|M.marinum_M --MEGCRVLQLGQIDRTDDK---PPYRQIASMLREAISSSRFPPGERLPS
MUL_0525|M.ulcerans_Agy99 --MEGSQVLQLGQIDRADDK---PPYRQIASMLRGAIISGELEAGGRLPS
MAV_1744|M.avium_104 ------MQQRSDKAGPVTAAAGVPLHRQLFLVLHDEIDRGVIAPGEALPT
TH_4115|M.thermoresistible__bu ---------------------VQSSYIQVADQLRDLILRGDLAVGQKLPS
: : : * * .
Mflv_1234|M.gilvum_PYR-GCK ERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRSGGIFISHA-------
MSMEG_0268|M.smegmatis_MC2_155 ERDLAEKYGTSRSSLRQVLAALEEAGLVHRVIGRSGGIFISHG-------
MAB_0953|M.abscessus_ATCC_1997 EREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRAD-------
Mvan_2288|M.vanbaalenii_PYR-1 EVEIATSLGVSRMTLRQALSAVEAKGLIDRRRGRFGGNFVAAP-------
Mb0816c|M.bovis_AF2122/97 ERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGL--GTFVADP-------
Rv0792c|M.tuberculosis_H37Rv ERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGL--GTFVADP-------
MMAR_4842|M.marinum_M EAELIEHFGVARMTVRQAMQELRSDGLVISQHGR--GVFVRPTPPIRRLA
MUL_0525|M.ulcerans_Agy99 EAELIEYFGVARMTVRQAVQELRTEGLVISEHGR--GVFVRPAPPIRWLA
MAV_1744|M.avium_104 EQTLCDQFGVSRITVRRALADLAAQGYIERRQGV--GSFVRQH-------
TH_4115|M.thermoresistible__bu EAEMAPLLGVSRSTIREALRILTTEHLIETRRGIQGGAFVAVP-------
* : :* ::* .: : : * * *:
Mflv_1234|M.gilvum_PYR-GCK ----QVQRSLTDVVGVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGIA
MSMEG_0268|M.smegmatis_MC2_155 ----QVERNLSDVVGVPAFLANQGYVAGTRILSTRITTPDQTTRTALRLG
MAB_0953|M.abscessus_ATCC_1997 ----VVQRNVAELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIA
Mvan_2288|M.vanbaalenii_PYR-1 ----RFEFDHASLPGFTEQMRRFEVEAGAQVLMATTGRPDAEVSRALGLR
Mb0816c|M.bovis_AF2122/97 ----VEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL-
Rv0792c|M.tuberculosis_H37Rv ----VEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL-
MMAR_4842|M.marinum_M SDRFARQHRAEGKAAFSVEAEKSGYSPQVDNIAVSREKPNSFIAEQLRIS
MUL_0525|M.ulcerans_Agy99 SDRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLRLT
MAV_1744|M.avium_104 -----DPADVPTGRSYLQGLRQTQFETEAEVVELGVRSAPRAVAEALGRS
TH_4115|M.thermoresistible__bu -----DSERLEGMFNTSFSMLALTNQVDARSFLQAMRALEGPAAALAAAA
. .
Mflv_1234|M.gilvum_PYR-GCK ADDFVIEIQRLRLADGSPISLELAQFPAEAFPGLLEQQLGGS----LYEI
MSMEG_0268|M.smegmatis_MC2_155 PGEYVVEIQRVRLADGSPISLEQAQFPAEKFPGLLEQQLGGS----LYEV
MAB_0953|M.abscessus_ATCC_1997 EGAEVFDVRRLRYADGVPLSVDTAYFPAELVPDLLEQPLGGS----LYEL
Mvan_2288|M.vanbaalenii_PYR-1 RTDQVHRILRARTANGEPIVLEEAYLPAAVFPGMLSKNLQAS----LYAL
Mb0816c|M.bovis_AF2122/97 --VEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAM
Rv0792c|M.tuberculosis_H37Rv --VEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAM
MMAR_4842|M.marinum_M ADDDIVVRSRRYLANGRPVETAVSYIPAAFAEGTR-IEQVDTGPGGIYAR
MUL_0525|M.ulcerans_Agy99 ADDEVVVRSRRYLADGKPVETATSYIPVAFAQGTK-IEQTDTGPGGIYAR
MAV_1744|M.avium_104 GELLHIVRVRRQRRTREPLMVTDAWLPPELAPVLTERALRRAP---LYEL
TH_4115|M.thermoresistible__bu RGGDQVEELKRTAAMVDPADQEAAMQQSADFHSAILRASGNK-------L
: * :
Mflv_1234|M.gilvum_PYR-GCK LESEYGLVTARADERIEAVNATPEEANLLGIKPRSALLLITRIAYDQHDT
MSMEG_0268|M.smegmatis_MC2_155 LESQYGLVPGRADERIEAVNATSNEATLLGIKPKAALLLITRVTFDQTGT
MAB_0953|M.abscessus_ATCC_1997 CQVRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGR
Mvan_2288|M.vanbaalenii_PYR-1 MRG-YGHAPCAADERIEATSATPEQARVLGVEPSCPLLLVVRTSFADNGV
Mb0816c|M.bovis_AF2122/97 WERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGK
Rv0792c|M.tuberculosis_H37Rv WERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGK
MMAR_4842|M.marinum_M LEEHG-HVLARFTEEVAARMPTPEERRQLELDSGVPVLTVLRTAYDTNDV
MUL_0525|M.ulcerans_Agy99 FEEAG-HTLARFNEEVGARMPTPEERRALQLPPGAPVLTVVRTAYDTKDV
MAV_1744|M.avium_104 LSANG-VAVDRVRHEITAEIAGPRNAQLLDVPIGAALLRVNRLVYVGDRP
TH_4115|M.thermoresistible__bu LEAMGRPVSAVARSKFRRTVPG---LEFWERNQRAHQELLKAILAGDENL
. . :
Mflv_1234|M.gilvum_PYR-GCK PCEFSRDLFRGDRTRL------AVTAQGRGVGASPSVAAASVALHGPLAK
MSMEG_0268|M.smegmatis_MC2_155 PYEFSRDLFRGDRTAL------AVTAKGRGIAAASNSGTDNRTASVTLHR
MAB_0953|M.abscessus_ATCC_1997 PFEFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDD
Mvan_2288|M.vanbaalenii_PYR-1 AVEFSRDYHRSDRTTIR-------------IQSRADPVRQGY--------
Mb0816c|M.bovis_AF2122/97 PLEVVVFHHRPERYQFS-----------VTLPRTLPGSGAGIIEKRDFA-
Rv0792c|M.tuberculosis_H37Rv PLEVVVFHHRPERYQFS-----------VTLPRTLPGSGAGIIEKRDFA-
MMAR_4842|M.marinum_M AVEVCDTVKVASAYLLE-----------YEFPAR----------------
MUL_0525|M.ulcerans_Agy99 AVEVCDTVKVASAYLLE-----------YDFSAR----------------
MAV_1744|M.avium_104 HHHVSALLSPSRSRVLLS------------QSADDMETGDGLRIAHDVGG
TH_4115|M.thermoresistible__bu AYELATRHIDEDLSPYYLP------------PEEADRDGAGA--------
..
Mflv_1234|M.gilvum_PYR-GCK APSA
MSMEG_0268|M.smegmatis_MC2_155 QVG-
MAB_0953|M.abscessus_ATCC_1997 TLLA
Mvan_2288|M.vanbaalenii_PYR-1 ----
Mb0816c|M.bovis_AF2122/97 ----
Rv0792c|M.tuberculosis_H37Rv ----
MMAR_4842|M.marinum_M ----
MUL_0525|M.ulcerans_Agy99 ----
MAV_1744|M.avium_104 PRG-
TH_4115|M.thermoresistible__bu ----