For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERELIDRSGLSRVTVRAAVGMLQ RQGWLVRRQGLGTFVADPVEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVEVLCIR RRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRIAQATHEIHAAGASPDVADAL GLAVGSPVLVVDRTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | - | 100% (269) | GntR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb0505 | - | 4e-06 | 34.38% (64) | GntR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb0601 | - | 3e-05 | 36.99% (73) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2603 | - | 2e-20 | 32.20% (236) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 1e-151 | 100.00% (269) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 7e-18 | 29.72% (249) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 4e-93 | 65.91% (264) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 1e-106 | 71.91% (267) | mercuric reductase/transcriptional regulator, fusion |
| M. smegmatis MC2 155 | MSMEG_4659 | - | 1e-21 | 31.78% (236) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_4188 | - | 1e-20 | 32.51% (243) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 2e-93 | 65.53% (264) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4015 | - | 6e-22 | 33.05% (236) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL
Rv0792c|M.tuberculosis_H37Rv MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL
MAV_0738|M.avium_104 MVPDQ----LDLDAADLRISRGS-VPASTQLAEALKAAIVKQRLPRGARL
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGS-VPASVQLAELLRTQILERALSPGSRL
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGS-VPASVQLAELLRTQILERALSPGSRL
Mflv_2603|M.gilvum_PYR-GCK ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRF
Mvan_4015|M.vanbaalenii_PYR-1 ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRGGELAPGDRF
MSMEG_4659|M.smegmatis_MC2_155 ----------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRF
MAB_0953|M.abscessus_ATCC_1997 ------------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRL
TH_4188|M.thermoresistible__bu ---------------------VRPRPAYQVLRDRLRDDIAAGRYRDGTRL
* : : : * *:
Mb0816c|M.bovis_AF2122/97 PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL
Rv0792c|M.tuberculosis_H37Rv PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL
MAV_0738|M.avium_104 PTERELVDRTRVSRVTVRAAVGLLERQGWLVRRQGLG--TFVANPVKQEL
MMAR_2560|M.marinum_M PTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLG--TFVAEPVKQDL
MUL_3201|M.ulcerans_Agy99 PTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLG--TFVAEPVEQDL
Mflv_2603|M.gilvum_PYR-GCK ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR
Mvan_4015|M.vanbaalenii_PYR-1 ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR
MSMEG_4659|M.smegmatis_MC2_155 ENELALASRLNLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQTPVHRP
MAB_0953|M.abscessus_ATCC_1997 GSEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRN
TH_4188|M.thermoresistible__bu PTESELMAQYGVSRQTVRRAFQDLVAEGSVYRVPGRG-------TYAADR
.* : : :** *.* *. * * : * * *
Mb0816c|M.bovis_AF2122/97 SCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIR
Rv0792c|M.tuberculosis_H37Rv SCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIR
MAV_0738|M.avium_104 GPGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHLT---KVLCVH
MMAR_2560|M.marinum_M ESGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRS---EVLRIQ
MUL_3201|M.ulcerans_Agy99 ESGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRS---EVLRIQ
Mflv_2603|M.gilvum_PYR-GCK -VELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLAEGREVASIQ
Mvan_4015|M.vanbaalenii_PYR-1 -VELTSLFDDLARAGQEPTTRLLEYHVGPPDEDVARELNLAEGRDVASIR
MSMEG_4659|M.smegmatis_MC2_155 -VELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIEPGSEIAYMR
MAB_0953|M.abscessus_ATCC_1997 VAELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVR
TH_4188|M.thermoresistible__bu YLRQFGSIEDLMALSDDTTMEVRSGLRRRVDVDAASRLRLDDDVVHTVVF
* . . : * :
Mb0816c|M.bovis_AF2122/97 RRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET------TYAMWE
Rv0792c|M.tuberculosis_H37Rv RRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET------TYAMWE
MAV_0738|M.avium_104 RRFRDGEQPLALMIAYLPPGLG-EAVEPLLKSATDTQTGRAMESTYTMWE
MMAR_2560|M.marinum_M RRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATAT------TYTMWE
MUL_3201|M.ulcerans_Agy99 RRYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTAT------TYTMWE
Mflv_2603|M.gilvum_PYR-GCK RLRCANGEPLALMTNHLPADIAPDAEELGNIGLYQALR------------
Mvan_4015|M.vanbaalenii_PYR-1 RLRCANGEPLALMTNYLPAEIAPDAEELESNGLYQSLR------------
MSMEG_4659|M.smegmatis_MC2_155 RLRSSNGQPLALMTNYLPAALAPDEDELARSGLYQSLR------------
MAB_0953|M.abscessus_ATCC_1997 RLRYADGVPLSVDTAYFPAELVPDLLEQPLGGSLYELC-----------Q
TH_4188|M.thermoresistible__bu RRLHAG-APFVSTVVHLPDRAAHHLHGCAELRTGAVST----HTVIGLLE
* . *: ::*
Mb0816c|M.bovis_AF2122/97 RRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPL
Rv0792c|M.tuberculosis_H37Rv RRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPL
MAV_0738|M.avium_104 RRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLERTSYGHDDTPL
MMAR_2560|M.marinum_M QRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPL
MUL_3201|M.ulcerans_Agy99 QRLGVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPL
Mflv_2603|M.gilvum_PYR-GCK -ARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMARTAFDDSGAAV
Mvan_4015|M.vanbaalenii_PYR-1 -ARGVHIRLARQRIGARSATRAEASLLDEKPNAPLLTMARTAFDDSGAAV
MSMEG_4659|M.smegmatis_MC2_155 -ARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVMERTAFDDSGRIV
MAB_0953|M.abscessus_ATCC_1997 VRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPF
TH_4188|M.thermoresistible__bu PHLEEPIDQAAQSITVAPADDDTADAVGVEPGHPMLRIDRLYSDRTGRPV
: : . * * :. *:* : * . .
Mb0816c|M.bovis_AF2122/97 EVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA--------------
Rv0792c|M.tuberculosis_H37Rv EVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA--------------
MAV_0738|M.avium_104 EVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG----------------
MMAR_2560|M.marinum_M EVVLFHHRPERYEFCVTLPRTMPGQRAGMTER------------------
MUL_3201|M.ulcerans_Agy99 EVVLFHHRPERYEFCVTLPRTMPGQRAGMTER------------------
Mflv_2603|M.gilvum_PYR-GCK EFGNHCYRASRYYFDTTLVDR-----------------------------
Mvan_4015|M.vanbaalenii_PYR-1 EFGNHCYRASRYYFDTTLVDR-----------------------------
MSMEG_4659|M.smegmatis_MC2_155 EYGSHAYRASRYYFDTTLVDR-----------------------------
MAB_0953|M.abscessus_ATCC_1997 EFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDDTL
TH_4188|M.thermoresistible__bu ELSVSHFLPEQYTYRVTLRRE-----------------------------
* . ..: .*:
Mb0816c|M.bovis_AF2122/97 --
Rv0792c|M.tuberculosis_H37Rv --
MAV_0738|M.avium_104 --
MMAR_2560|M.marinum_M --
MUL_3201|M.ulcerans_Agy99 --
Mflv_2603|M.gilvum_PYR-GCK --
Mvan_4015|M.vanbaalenii_PYR-1 --
MSMEG_4659|M.smegmatis_MC2_155 --
MAB_0953|M.abscessus_ATCC_1997 LA
TH_4188|M.thermoresistible__bu --