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PVQSEELRRRLVADINAGTPGAKLGSERDLAEKYGTSRSSLRQVLAALEEAGLVHRVIGRSGGIFISHGQ VERNLSDVVGVPAFLANQGYVAGTRILSTRITTPDQTTRTALRLGPGEYVVEIQRVRLADGSPISLEQAQ FPAEKFPGLLEQQLGGSLYEVLESQYGLVPGRADERIEAVNATSNEATLLGIKPKAALLLITRVTFDQTG TPYEFSRDLFRGDRTALAVTAKGRGIAAASNSGTDNRTASVTLHRQVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0268 | - | - | 100% (259) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_0778 | - | 2e-47 | 42.67% (232) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1227 | - | 2e-22 | 29.91% (234) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 2e-09 | 28.24% (216) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1234 | - | 1e-104 | 75.29% (255) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 2e-09 | 28.24% (216) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 5e-50 | 42.00% (250) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 5e-12 | 26.50% (234) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5032 | - | 1e-21 | 31.00% (229) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3932 | - | 3e-18 | 31.88% (229) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 1e-11 | 26.38% (235) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | 1e-102 | 78.06% (237) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
Mflv_1234|M.gilvum_PYR-GCK ----------MVEPIWRRRGGPVPTQTEDLRRRIVADINAGK--PGTKLG
Mvan_5574|M.vanbaalenii_PYR-1 ----------------------MPTQTEDLRRRIVSDINAGV--PGTKLG
MSMEG_0268|M.smegmatis_MC2_155 ----------------------MPVQSEELRRRLVADINAGT--PGAKLG
MAB_0953|M.abscessus_ATCC_1997 -----------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRLG
MAV_5032|M.avium_104 ----------------------------MLRSQILEGAYGGLAAARPALP
TH_3932|M.thermoresistible__bu ------MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERARPGDRLP
: *
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVEQDLE
Mflv_1234|M.gilvum_PYR-GCK SERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRSGGIFISHAQVQRSL
Mvan_5574|M.vanbaalenii_PYR-1 SERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRAGGIFISHAQVQRSL
MSMEG_0268|M.smegmatis_MC2_155 SERDLAEKYGTSRSSLRQVLAALEEAGLVHRVIGRSGGIFISHGQVERNL
MAB_0953|M.abscessus_ATCC_1997 SEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRNV
MAV_5032|M.avium_104 SESALAAELGVSRNAIREALELLRGEGLITRVQG--SGTFVTGAKLRQDL
TH_3932|M.thermoresistible__bu SEAELSGQFGVNRLTVRRALHELAQRGIIETVHG--RGSFVARQPVRYRL
:* : . .* ::* .: * * : * * *: .
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRSE---VLRIQR
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRSE---VLRIQR
Mflv_1234|M.gilvum_PYR-GCK TDVVGVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGIAADDFVIEIQR
Mvan_5574|M.vanbaalenii_PYR-1 TDVVGVPAFLASQGYVAGTRVLSTKICAPDSATQQALKIGADDFVIEIQR
MSMEG_0268|M.smegmatis_MC2_155 SDVVGVPAFLANQGYVAGTRILSTRITTPDQTTRTALRLGPGEYVVEIQR
MAB_0953|M.abscessus_ATCC_1997 AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVRR
MAV_5032|M.avium_104 NRLKGLAESLAGHRLPVENKVLSIRESTATPFVAAKLQLPENAPILFIER
TH_3932|M.thermoresistible__bu SATRDASFTRGMRELGHPVRIEVLG-AETTRCRRLRTELHTAGEVLTTTT
. : . :.
Mb0816c|M.bovis_AF2122/97 RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
Rv0792c|M.tuberculosis_H37Rv RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
MMAR_2560|M.marinum_M RYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTMWEQRLGVRI
MUL_3201|M.ulcerans_Agy99 RYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTATTYTMWEQRLGVRI
Mflv_1234|M.gilvum_PYR-GCK LRLADGSPISLELAQFPAEAFPGLLEQQLGG-----SLYEILESEYGLVT
Mvan_5574|M.vanbaalenii_PYR-1 LRLADGSPISLELAQFPADAFPGLLEQQLGG-----SLYEILESQYGLVT
MSMEG_0268|M.smegmatis_MC2_155 VRLADGSPISLEQAQFPAEKFPGLLEQQLGG-----SLYEVLESQYGLVP
MAB_0953|M.abscessus_ATCC_1997 LRYADGVPLSVDTAYFPAELVPDLLEQPLGG-----SLYELCQVRYGLQA
MAV_5032|M.avium_104 LRSVGGLPLSLDTTSLRIGAIRIDADLDKQD------VFALIEQELGERL
TH_3932|M.thermoresistible__bu LRHVDGQPWSVSVTSIALDRFPGIAQQWSGS----TSLFDFLWQTFGVRM
.. * :: : : : . *
Mb0816c|M.bovis_AF2122/97 AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
Rv0792c|M.tuberculosis_H37Rv AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
MMAR_2560|M.marinum_M SSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
MUL_3201|M.ulcerans_Agy99 SSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
Mflv_1234|M.gilvum_PYR-GCK ARADERIEAVNATPEEANLLGIKPRSALLLITRIAYDQHDTPCEFSRDLF
Mvan_5574|M.vanbaalenii_PYR-1 ARADERIEAVNATPEEANLLGIKAKSALLLITRITYDQHDTPCEFSRDLF
MSMEG_0268|M.smegmatis_MC2_155 GRADERIEAVNATSNEATLLGIKPKAALLLITRVTFDQTGTPYEFSRDLF
MAB_0953|M.abscessus_ATCC_1997 DSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPFEFSYDLF
MAV_5032|M.avium_104 GWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRDGTPFDLETVRY
TH_3932|M.thermoresistible__bu RRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPVAVVRHRF
: . . * * * : .:* : . * . .
Mb0816c|M.bovis_AF2122/97 RPERYQFSVTLPRTLPGSGAGIIEKRDFA--------------------
Rv0792c|M.tuberculosis_H37Rv RPERYQFSVTLPRTLPGSGAGIIEKRDFA--------------------
MMAR_2560|M.marinum_M RPERYEFCVTLPRTMPGQRAGMTER------------------------
MUL_3201|M.ulcerans_Agy99 RPERYEFCVTLPRTMPGQRAGMTER------------------------
Mflv_1234|M.gilvum_PYR-GCK RGDRTRL------AVTAQGRGVGASPS----VAAASVALHGPLAKAPSA
Mvan_5574|M.vanbaalenii_PYR-1 RGDRTRL------AVTAQGRGVGVQPS----VAAASVALQSPPI-----
MSMEG_0268|M.smegmatis_MC2_155 RGDRTAL------AVTAKGRGIAAASNSGTDNRTASVTLHRQVG-----
MAB_0953|M.abscessus_ATCC_1997 RADRVRLTATMTSAVAQESRGVDGKVER----VVSRLAAHRRPDDTLLA
MAV_5032|M.avium_104 RGDRCSL------VTTATREDAPPQ------------------------
TH_3932|M.thermoresistible__bu RGDRVELTVDLA-------------------------------------
* :* :