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VPTQTEDLRRRIVSDINAGVPGTKLGSERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRAGGIFISHA QVQRSLTDVVGVPAFLASQGYVAGTRVLSTKICAPDSATQQALKIGADDFVIEIQRLRLADGSPISLELA QFPADAFPGLLEQQLGGSLYEILESQYGLVTARADERIEAVNATPEEANLLGIKAKSALLLITRITYDQH DTPCEFSRDLFRGDRTRLAVTAQGRGVGVQPSVAAASVALQSPPI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | - | 100% (255) | UbiC transcription regulator-associated domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | 2e-35 | 39.25% (214) | UbiC transcription regulator-associated domain-containing |
| M. vanbaalenii PYR-1 | Mvan_3927 | - | 3e-24 | 34.33% (233) | UbiC transcription regulator-associated domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 7e-12 | 27.71% (249) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1234 | - | 1e-128 | 92.89% (253) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 8e-12 | 27.71% (249) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 9e-51 | 45.42% (240) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4842 | - | 5e-15 | 30.14% (209) | regulatory protein |
| M. avium 104 | MAV_5032 | - | 6e-18 | 28.82% (229) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0268 | - | 1e-102 | 78.06% (237) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3932 | - | 2e-17 | 28.44% (211) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 5e-14 | 27.31% (216) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
Mvan_5574|M.vanbaalenii_PYR-1 ----------------------MPTQTEDLRRRIVSDINAGV--PGTKLG
Mflv_1234|M.gilvum_PYR-GCK ----------MVEPIWRRRGGPVPTQTEDLRRRIVADINAGK--PGTKLG
MSMEG_0268|M.smegmatis_MC2_155 ----------------------MPVQSEELRRRLVADINAGT--PGAKLG
MAB_0953|M.abscessus_ATCC_1997 -----------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRLG
MAV_5032|M.avium_104 ----------------------------MLRSQILEGAYGGLAAARPALP
TH_3932|M.thermoresistible__bu ------MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERARPGDRLP
MMAR_4842|M.marinum_M ------MEGCRVLQLGQIDRTDDKPPYRQIASMLREAISSSRFPPGERLP
: *
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADP------
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADP------
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEP------
Mvan_5574|M.vanbaalenii_PYR-1 SERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRAGGIFISHA------
Mflv_1234|M.gilvum_PYR-GCK SERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRSGGIFISHA------
MSMEG_0268|M.smegmatis_MC2_155 SERDLAEKYGTSRSSLRQVLAALEEAGLVHRVIGRSGGIFISHG------
MAB_0953|M.abscessus_ATCC_1997 SEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRAD------
MAV_5032|M.avium_104 SESALAAELGVSRNAIREALELLRGEGLITRVQG--SGTFVTGA------
TH_3932|M.thermoresistible__bu SEAELSGQFGVNRLTVRRALHELAQRGIIETVHG--RGSFVARQ------
MMAR_4842|M.marinum_M SEAELIEHFGVARMTVRQAMQELRSDGLVISQHG--RGVFVRPTPPIRRL
:* : . * ::* .: * * : * * *:
Mb0816c|M.bovis_AF2122/97 -----VEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL
Rv0792c|M.tuberculosis_H37Rv -----VEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL
MUL_3201|M.ulcerans_Agy99 -----VEQDLESGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGR
Mvan_5574|M.vanbaalenii_PYR-1 -----QVQRSLTDVVGVPAFLASQGYVAGTRVLSTKICAPDSATQQALKI
Mflv_1234|M.gilvum_PYR-GCK -----QVQRSLTDVVGVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGI
MSMEG_0268|M.smegmatis_MC2_155 -----QVERNLSDVVGVPAFLANQGYVAGTRILSTRITTPDQTTRTALRL
MAB_0953|M.abscessus_ATCC_1997 -----VVQRNVAELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEI
MAV_5032|M.avium_104 -----KLRQDLNRLKGLAESLAGHRLPVENKVLSIRESTATPFVAAKLQL
TH_3932|M.thermoresistible__bu -----PVRYRLSATRDASFTRGMRELGHPVRIEVLG-AETTRCRRLRTEL
MMAR_4842|M.marinum_M ASDRFARQHRAEGKAAFSVEAEKSGYSPQVDNIAVSREKPNSFIAEQLRI
. . .
Mb0816c|M.bovis_AF2122/97 VE---VLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTY
Rv0792c|M.tuberculosis_H37Rv VE---VLCIRRRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTY
MUL_3201|M.ulcerans_Agy99 SE---VLRIQRRYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTATTY
Mvan_5574|M.vanbaalenii_PYR-1 GADDFVIEIQRLRLADGSPISLELAQFPADAFPGLLEQQLGG-----SLY
Mflv_1234|M.gilvum_PYR-GCK AADDFVIEIQRLRLADGSPISLELAQFPAEAFPGLLEQQLGG-----SLY
MSMEG_0268|M.smegmatis_MC2_155 GPGEYVVEIQRVRLADGSPISLEQAQFPAEKFPGLLEQQLGG-----SLY
MAB_0953|M.abscessus_ATCC_1997 AEGAEVFDVRRLRYADGVPLSVDTAYFPAELVPDLLEQPLGG-----SLY
MAV_5032|M.avium_104 PENAPILFIERLRSVGGLPLSLDTTSLRIGAIRIDADLDKQD------VF
TH_3932|M.thermoresistible__bu HTAGEVLTTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSGS----TSLF
MMAR_4842|M.marinum_M SADDDIVVRSRRYLANGRPVETAVSYIPAAFAEGTRIEQVDTG---PGGI
:. .. * :
Mb0816c|M.bovis_AF2122/97 AMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTND
Rv0792c|M.tuberculosis_H37Rv AMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTND
MUL_3201|M.ulcerans_Agy99 TMWEQRLGVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDG
Mvan_5574|M.vanbaalenii_PYR-1 EILESQYGLVTARADERIEAVNATPEEANLLGIKAKSALLLITRITYDQH
Mflv_1234|M.gilvum_PYR-GCK EILESEYGLVTARADERIEAVNATPEEANLLGIKPRSALLLITRIAYDQH
MSMEG_0268|M.smegmatis_MC2_155 EVLESQYGLVPGRADERIEAVNATSNEATLLGIKPKAALLLITRVTFDQT
MAB_0953|M.abscessus_ATCC_1997 ELCQVRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTD
MAV_5032|M.avium_104 ALIEQELGERLGWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRD
TH_3932|M.thermoresistible__bu DFLWQTFGVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQH
MMAR_4842|M.marinum_M YARLEEHGHVLARFTEEVAARMPTPEERRQLELDSGVPVLTVLRTAYDTN
* . . * : .:* :
Mb0816c|M.bovis_AF2122/97 GKPLEVVVFHHRPERYQF-------SVTLPRTLPGSGAG--------IIE
Rv0792c|M.tuberculosis_H37Rv GKPLEVVVFHHRPERYQF-------SVTLPRTLPGSGAG--------IIE
MUL_3201|M.ulcerans_Agy99 DKPLEVVLFHHRPERYEF-------CVTLPRTMPGQRAG--------MTE
Mvan_5574|M.vanbaalenii_PYR-1 DTPCEFSRDLFRGDRTRL------AVTAQGRGVGVQPS----VAAASVAL
Mflv_1234|M.gilvum_PYR-GCK DTPCEFSRDLFRGDRTRL------AVTAQGRGVGASPS----VAAASVAL
MSMEG_0268|M.smegmatis_MC2_155 GTPYEFSRDLFRGDRTAL------AVTAKGRGIAAASNSGTDNRTASVTL
MAB_0953|M.abscessus_ATCC_1997 GRPFEFSYDLFRADRVRLTATMTSAVAQESRGVDGKVER----VVSRLAA
MAV_5032|M.avium_104 GTPFDLETVRYRGDRCSL-------VTTATREDAPPQ-------------
TH_3932|M.thermoresistible__bu GAPVAVVRHRFRGDRVEL-------TVDLA--------------------
MMAR_4842|M.marinum_M DVAVEVCDTVKVASAYLL-------EYEFPAR------------------
. . . . :
Mb0816c|M.bovis_AF2122/97 KRDFA-----
Rv0792c|M.tuberculosis_H37Rv KRDFA-----
MUL_3201|M.ulcerans_Agy99 R---------
Mvan_5574|M.vanbaalenii_PYR-1 QSPPI-----
Mflv_1234|M.gilvum_PYR-GCK HGPLAKAPSA
MSMEG_0268|M.smegmatis_MC2_155 HRQVG-----
MAB_0953|M.abscessus_ATCC_1997 HRRPDDTLLA
MAV_5032|M.avium_104 ----------
TH_3932|M.thermoresistible__bu ----------
MMAR_4842|M.marinum_M ----------