For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MEESEGGPVAEDVRRRILSMLAQGTLHPGSRLGSEREMAERFAVSRATVRSALVPLSRAGILERQTGRGG GTFVRADVVQRNVAELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVRRLRYADGV PLSVDTAYFPAELVPDLLEQPLGGSLYELCQVRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAIT RVTRNTDGRPFEFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDDTLLA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0953 | - | - | 100% (273) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2239 | - | 7e-21 | 31.30% (230) | GntR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1498c | - | 3e-20 | 36.36% (220) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 6e-18 | 29.72% (249) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1234 | - | 2e-52 | 44.27% (262) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 6e-18 | 29.72% (249) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2560 | - | 1e-16 | 27.82% (248) | GntR family transcriptional regulator |
| M. avium 104 | MAV_3402 | - | 4e-20 | 30.08% (246) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0778 | - | 1e-103 | 73.66% (262) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_3932 | - | 9e-17 | 29.77% (215) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 1e-16 | 27.31% (249) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | 1e-50 | 45.42% (240) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MAB_0953|M.abscessus_ATCC_1997 ----------MEE-------SEGGPVAEDVRRRILSMLAQGTLHPGSRLG
MSMEG_0778|M.smegmatis_MC2_155 ----------MEE-------TSGGPVAEDVRRRILSMLAQGMLRPGSRLG
Mflv_1234|M.gilvum_PYR-GCK ----------MVEPIWRRRGGPVPTQTEDLRRRIVADINAG--KPGTKLG
Mvan_5574|M.vanbaalenii_PYR-1 ----------------------MPTQTEDLRRRIVSDINAG--VPGTKLG
TH_3932|M.thermoresistible__bu -----MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIER-ARPGDRLP
MAV_3402|M.avium_104 ------------MAHPVPIGGPRADRARRVADVLRQQIHADAYPDG--LP
: : : * *
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVEQDLE
MAB_0953|M.abscessus_ATCC_1997 SEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRNV
MSMEG_0778|M.smegmatis_MC2_155 TEREMAETFAVSRSTLRSALLPLSQAGVLERRTGRNGGTFVRADVVQRNA
Mflv_1234|M.gilvum_PYR-GCK SERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRSGGIFISHAQVQRSL
Mvan_5574|M.vanbaalenii_PYR-1 SERELAERYRTSRSSLRQVLAALEEAGLVDRVIGRAGGIFISHAQVQRSL
TH_3932|M.thermoresistible__bu SEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRGSFVARQPVRYRLSA
MAV_3402|M.avium_104 AELELAAEFSVSRNTIREALAVLKREGLIDRGPR--VGTHVAQRKYDHAL
:* *: .* ::* .: * * :
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVE---VLCIRR
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRSE---VLRIQR
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRSE---VLRIQR
MAB_0953|M.abscessus_ATCC_1997 AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVRR
MSMEG_0778|M.smegmatis_MC2_155 AELVGLPARLHSGGHTSTSRVLGTDRRPATAIEAEALEVPLGTDIFTIRR
Mflv_1234|M.gilvum_PYR-GCK TDVVGVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGIAADDFVIEIQR
Mvan_5574|M.vanbaalenii_PYR-1 TDVVGVPAFLASQGYVAGTRVLSTKICAPDSATQQALKIGADDFVIEIQR
TH_3932|M.thermoresistible__bu TRDASFTRGMRELGHPVRIEVLGAETTRCRRLRTELHTAGE---VLTTTT
MAV_3402|M.avium_104 DALLGLKETFKDLG-EVRNEVRAAMPVTAPPSVARRLRLAPGEQAVFIER
. : * * . .
Mb0816c|M.bovis_AF2122/97 RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
Rv0792c|M.tuberculosis_H37Rv RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
MMAR_2560|M.marinum_M RYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTMWEQRLGVRI
MUL_3201|M.ulcerans_Agy99 RYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTATTYTMWEQRLGVRI
MAB_0953|M.abscessus_ATCC_1997 LRYADGVPLSVDTAYFPAELVPDLLEQPLGG-----SLYELCQVRYGLQA
MSMEG_0778|M.smegmatis_MC2_155 LRFADGVPLSVDLACFVAGRMNDLLEQPLGG-----SLYELLQVRYGLTP
Mflv_1234|M.gilvum_PYR-GCK LRLADGSPISLELAQFPAEAFPGLLEQQLGG-----SLYEILESEYGLVT
Mvan_5574|M.vanbaalenii_PYR-1 LRLADGSPISLELAQFPADAFPGLLEQQLGG-----SLYEILESQYGLVT
TH_3932|M.thermoresistible__bu LRHVDGQPWSVSVTSIALDRFPGIAQQWSGS----TSLFDFLWQTFGVRM
MAV_3402|M.avium_104 LRYLGELPLSLDLTYLAPPIGRQVLEHSLETN----DVFALIEQVSGQRL
. * :: : : : : *
Mb0816c|M.bovis_AF2122/97 AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
Rv0792c|M.tuberculosis_H37Rv AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
MMAR_2560|M.marinum_M SSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
MUL_3201|M.ulcerans_Agy99 SSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
MAB_0953|M.abscessus_ATCC_1997 DSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPFEFSYDLF
MSMEG_0778|M.smegmatis_MC2_155 ATTTETIEVVSASPREAQWLDVAHRKPLLAITRVTRDDTGRPFEYAYDLF
Mflv_1234|M.gilvum_PYR-GCK ARADERIEAVNATPEEANLLGIKPRSALLLITRIAYDQHDTPCEFSRDLF
Mvan_5574|M.vanbaalenii_PYR-1 ARADERIEAVNATPEEANLLGIKAKSALLLITRITYDQHDTPCEFSRDLF
TH_3932|M.thermoresistible__bu RRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPVAVVRHRF
MAV_3402|M.avium_104 GSAALALEAIPADAHSAATLQVPDGAALLMLERLTSLADGTPVDLEYIRM
: . . * * * : .:* : . *
Mb0816c|M.bovis_AF2122/97 RPERYQFSVTLP-------RTLPGSGAGIIEKRDFA---------
Rv0792c|M.tuberculosis_H37Rv RPERYQFSVTLP-------RTLPGSGAGIIEKRDFA---------
MMAR_2560|M.marinum_M RPERYEFCVTLP-------RTMPGQRAGMTER-------------
MUL_3201|M.ulcerans_Agy99 RPERYEFCVTLP-------RTMPGQRAGMTER-------------
MAB_0953|M.abscessus_ATCC_1997 RADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDDTLLA
MSMEG_0778|M.smegmatis_MC2_155 RADRVRLTAT--------SHGTVGAVQRSVSTTA-----------
Mflv_1234|M.gilvum_PYR-GCK RGDRTRLAVTAQ------GRGVGASPSVAAASVALHGPLAKAPSA
Mvan_5574|M.vanbaalenii_PYR-1 RGDRTRLAVTAQ------GRGVGVQPSVAAASVALQSPPI-----
TH_3932|M.thermoresistible__bu RGDRVELTVDLA---------------------------------
MAV_3402|M.avium_104 RGDRITMRGNLF-------RAEPMRSNS-----------------
* :* :