For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VEGSQVLQLGQIDRADDKPPYRQIASMLRGAIISGELEAGGRLPSEAELIEYFGVARMTVRQAVQELRTE GLVISEHGRGVFVRPAPPIRWLASDRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERL RLTADDEVVVRSRRYLADGKPVETATSYIPVAFAQGTKIEQTDTGPGGIYARFEEAGHTLARFNEEVGAR MPTPEERRALQLPPGAPVLTVVRTAYDTKDVAVEVCDTVKVASAYLLEYDFSAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0525 | - | - | 100% (264) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_3201 | - | 4e-17 | 32.47% (231) | GntR family transcriptional regulator |
| M. ulcerans Agy99 | MUL_4818 | - | 2e-13 | 30.00% (230) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 6e-20 | 32.90% (231) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2603 | - | 7e-23 | 29.44% (248) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 6e-20 | 32.90% (231) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 5e-11 | 44.78% (67) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4842 | - | 1e-119 | 79.55% (264) | regulatory protein |
| M. avium 104 | MAV_0738 | - | 1e-20 | 32.07% (237) | mercuric reductase/transcriptional regulator, fusion |
| M. smegmatis MC2 155 | MSMEG_4659 | - | 8e-24 | 27.42% (248) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0099 | - | 7e-16 | 30.94% (223) | transcriptional regulator, GntR family protein |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | 4e-23 | 31.47% (232) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0525|M.ulcerans_Agy99 -----MEGSQVLQLGQIDRADDKPPYRQIASMLRGAIISGELEAGGRLPS
MMAR_4842|M.marinum_M -----MEGCRVLQLGQIDRTDDKPPYRQIASMLREAISSSRFPPGERLPS
Mb0816c|M.bovis_AF2122/97 ---MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPS
Rv0792c|M.tuberculosis_H37Rv ---MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPS
MAV_0738|M.avium_104 ---MVPDQLDLDAADLRISRGSVPASTQLAEALKAAIVKQRLPRGARLPT
Mflv_2603|M.gilvum_PYR-GCK --------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRFEN
MSMEG_4659|M.smegmatis_MC2_155 --------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRFEN
Mvan_2288|M.vanbaalenii_PYR-1 MRVLTVDAAPLAARPDLVGSSDLPAHARIAQWLEALIASGDLIPGDKLPP
TH_0099|M.thermoresistible__bu ----------------MTVSPADHRYLQVARILRKEIVDGVYPVGSQLPT
MAB_4644c|M.abscessus_ATCC_199 ---------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKLPG
::* : * . * ::
MUL_0525|M.ulcerans_Agy99 EAELIEYFGVARMTVRQAVQELRTEGLVISEHG--RGVFVRPAPPIRWLA
MMAR_4842|M.marinum_M EAELIEHFGVARMTVRQAMQELRSDGLVISQHG--RGVFVRPTPPIRRLA
Mb0816c|M.bovis_AF2122/97 ERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPV------
Rv0792c|M.tuberculosis_H37Rv ERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPV------
MAV_0738|M.avium_104 ERELVDRTRVSRVTVRAAVGLLERQGWLVRRQG--LGTFVANPV------
Mflv_2603|M.gilvum_PYR-GCK ELALAKRLTLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQNP-------
MSMEG_4659|M.smegmatis_MC2_155 ELALASRLNLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQTP-------
Mvan_2288|M.vanbaalenii_PYR-1 EVEIATSLGVSRMTLRQALSAVEAKGLIDRRRGRFGGNFVAAPR------
TH_0099|M.thermoresistible__bu EHELSERFSVSRYTIREALRRLREDNLISSRPR--AGTMVVPRP------
MAB_4644c|M.abscessus_ATCC_199 EVALCEEFGVSRATVREAIRDLKTKGLVSTRQG--AGVFVTSDR------
* : ::* * * *: : .. : . .*
MUL_0525|M.ulcerans_Agy99 SDRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLRLT
MMAR_4842|M.marinum_M SDRFARQHRAEGKAAFSVEAEKSGYSPQVDNIAVSREKPNSFIAEQLRIS
Mb0816c|M.bovis_AF2122/97 -----EQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV
Rv0792c|M.tuberculosis_H37Rv -----EQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV
MAV_0738|M.avium_104 -----KQELGPGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHLT
Mflv_2603|M.gilvum_PYR-GCK ------VHRRVELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLA
MSMEG_4659|M.smegmatis_MC2_155 ------VHRPVELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIE
Mvan_2288|M.vanbaalenii_PYR-1 -----FEFDHASLPGFTEQMRRFEVEAGAQVLMATTGRPDAEVSRALGLR
TH_0099|M.thermoresistible__bu -----SSHAYAQDVMSINDLLAFATGAKFAIESVAMVTIDDELADRTGLT
MAB_4644c|M.abscessus_ATCC_199 -----------PLGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERRNRS
. :
MUL_0525|M.ulcerans_Agy99 ADDEVVVRSRRYLADGK--PVETATSYIPVAFAQGTKIEQTDTGPGGIYA
MMAR_4842|M.marinum_M ADDDIVVRSRRYLANGR--PVETAVSYIPAAFAEGTRIEQVDTGPGGIYA
Mb0816c|M.bovis_AF2122/97 ---EVLCIRRRIRTGDQ--PLALVTAYLPPGVGPAVEPLLSGSADTET--
Rv0792c|M.tuberculosis_H37Rv ---EVLCIRRRIRTGDQ--PLALVTAYLPPGVGPAVEPLLSGSADTET--
MAV_0738|M.avium_104 ---KVLCVHRRFRDGEQ--PLALMIAYLPPGLGEAVEPLLKSATDTQTGR
Mflv_2603|M.gilvum_PYR-GCK EGREVASIQRLRCANGE--PLALMTNHLPADIAP-DAEELGNIGLYQA--
MSMEG_4659|M.smegmatis_MC2_155 PGSEIAYMRRLRSSNGQ--PLALMTNYLPAALAP-DEDELARSGLYQS--
Mvan_2288|M.vanbaalenii_PYR-1 RTDQVHRILRARTANGE--PIVLEEAYLPAAVFPGMLSKNLQASLYAL--
TH_0099|M.thermoresistible__bu VDEQWLAVLGYRQADGSDTPVCRTEYYINRAFAAVGRLLPSHTGPIFP--
MAB_4644c|M.abscessus_ATCC_199 ---DVAAIRRALVARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLD--
. . :: .
MUL_0525|M.ulcerans_Agy99 R--------FEEAGHTLARFNEEVGARMPTPEERRALQLPPGAPVLTVVR
MMAR_4842|M.marinum_M R--------LEEHGHVLARFTEEVAARMPTPEERRQLELDSGVPVLTVLR
Mb0816c|M.bovis_AF2122/97 ----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDR
Rv0792c|M.tuberculosis_H37Rv ----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDR
MAV_0738|M.avium_104 AMESTYTMWERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLER
Mflv_2603|M.gilvum_PYR-GCK ---------LRARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMAR
MSMEG_4659|M.smegmatis_MC2_155 ---------LRARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVMER
Mvan_2288|M.vanbaalenii_PYR-1 ---------MRGYGHAPCAADERIEATSATPEQARVLGVEPSCPLLLVVR
TH_0099|M.thermoresistible__bu -------LIEDMFGVSIIEVHQQISAVLLGPGLADRLRDEAGSPALEMQR
MAB_4644c|M.abscessus_ATCC_199 ----------ELFDSFSVRMREAMLALLAGSAER---PHDQEHHQWLFDA
. : * .
MUL_0525|M.ulcerans_Agy99 TAYDTKDVAVEVCDTVKVASAYLLEYDFSAR---------------
MMAR_4842|M.marinum_M TAYDTNDVAVEVCDTVKVASAYLLEYEFPAR---------------
Mb0816c|M.bovis_AF2122/97 TSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv TSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
MAV_0738|M.avium_104 TSYGHDDTPLEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG--
Mflv_2603|M.gilvum_PYR-GCK TAFDDSGAAVEFGNHCYRASRYYFDTTLVDR---------------
MSMEG_4659|M.smegmatis_MC2_155 TAFDDSGRIVEYGSHAYRASRYYFDTTLVDR---------------
Mvan_2288|M.vanbaalenii_PYR-1 TSFADNGVAVEFSRDYHRSDRTTIRIQSRADPVRQGY---------
TH_0099|M.thermoresistible__bu TYKTSDGDVAQVTVNTHPASRFRHSMTMRRVKP-------------
MAB_4644c|M.abscessus_ATCC_199 IVDGSTRRAVELATDQLQHVRMR-----------------------
: