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TSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERELIDRSGLSRVTVRAAVGMLQR QGWLVRRQGLGTFVADPVEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVEVLCIRR RIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRIAQATHEIHAAGASPDVADALG LAVGSPVLVVDRTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0792c | - | - | 100% (269) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) |
M. tuberculosis H37Rv | Rv0494 | - | 4e-06 | 34.38% (64) | GntR family transcriptional regulator |
M. tuberculosis H37Rv | Rv0586 | - | 3e-05 | 36.99% (73) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0816c | - | 1e-151 | 100.00% (269) | GntR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_2603 | - | 2e-20 | 32.20% (236) | UbiC transcription regulator-associated domain-containing |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0953 | - | 7e-18 | 29.72% (249) | GntR family transcriptional regulator |
M. marinum M | MMAR_2560 | - | 4e-93 | 65.91% (264) | GntR family transcriptional regulator |
M. avium 104 | MAV_0738 | - | 1e-106 | 71.91% (267) | mercuric reductase/transcriptional regulator, fusion |
M. smegmatis MC2 155 | MSMEG_4659 | - | 1e-21 | 31.78% (236) | GntR-family protein transcriptional regulator |
M. thermoresistible (build 8) | TH_4188 | - | 1e-20 | 32.51% (243) | PUTATIVE transcriptional regulator, GntR family |
M. ulcerans Agy99 | MUL_3201 | - | 2e-93 | 65.53% (264) | GntR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_4015 | - | 6e-22 | 33.05% (236) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment Rv0792c|M.tuberculosis_H37Rv MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL Mb0816c|M.bovis_AF2122/97 MTSVK----LDLDAADLRISRGS-VPASTQLAEALKAQIIQQRLPRGGRL MAV_0738|M.avium_104 MVPDQ----LDLDAADLRISRGS-VPASTQLAEALKAAIVKQRLPRGARL MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGS-VPASVQLAELLRTQILERALSPGSRL MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGS-VPASVQLAELLRTQILERALSPGSRL Mflv_2603|M.gilvum_PYR-GCK ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRF Mvan_4015|M.vanbaalenii_PYR-1 ----------MP--LTVELDRSSPVPLYYQLAQAIEAAIRGGELAPGDRF MSMEG_4659|M.smegmatis_MC2_155 ----------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRF MAB_0953|M.abscessus_ATCC_1997 ------------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRL TH_4188|M.thermoresistible__bu ---------------------VRPRPAYQVLRDRLRDDIAAGRYRDGTRL * : : : * *: Rv0792c|M.tuberculosis_H37Rv PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL Mb0816c|M.bovis_AF2122/97 PSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLG--TFVADPVEQEL MAV_0738|M.avium_104 PTERELVDRTRVSRVTVRAAVGLLERQGWLVRRQGLG--TFVANPVKQEL MMAR_2560|M.marinum_M PTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLG--TFVAEPVKQDL MUL_3201|M.ulcerans_Agy99 PTEQELIARSGVSRSTVRAAVGILEDEGWLVRRQGLG--TFVAEPVEQDL Mflv_2603|M.gilvum_PYR-GCK ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR Mvan_4015|M.vanbaalenii_PYR-1 ENELALAKRLTLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQNPVHRR MSMEG_4659|M.smegmatis_MC2_155 ENELALASRLNLSRPTTRRAIQELVDKGLLVRKRGVG--TQVVQTPVHRP MAB_0953|M.abscessus_ATCC_1997 GSEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRN TH_4188|M.thermoresistible__bu PTESELMAQYGVSRQTVRRAFQDLVAEGSVYRVPGRG-------TYAADR .* : : :** *.* *. * * : * * * Rv0792c|M.tuberculosis_H37Rv SCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIR Mb0816c|M.bovis_AF2122/97 SCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIR MAV_0738|M.avium_104 GPGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHLT---KVLCVH MMAR_2560|M.marinum_M ESGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRS---EVLRIQ MUL_3201|M.ulcerans_Agy99 ESGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRS---EVLRIQ Mflv_2603|M.gilvum_PYR-GCK -VELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLAEGREVASIQ Mvan_4015|M.vanbaalenii_PYR-1 -VELTSLFDDLARAGQEPTTRLLEYHVGPPDEDVARELNLAEGRDVASIR MSMEG_4659|M.smegmatis_MC2_155 -VELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIEPGSEIAYMR MAB_0953|M.abscessus_ATCC_1997 VAELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVR TH_4188|M.thermoresistible__bu YLRQFGSIEDLMALSDDTTMEVRSGLRRRVDVDAASRLRLDDDVVHTVVF * . . : * : Rv0792c|M.tuberculosis_H37Rv RRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET------TYAMWE Mb0816c|M.bovis_AF2122/97 RRIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTET------TYAMWE MAV_0738|M.avium_104 RRFRDGEQPLALMIAYLPPGLG-EAVEPLLKSATDTQTGRAMESTYTMWE MMAR_2560|M.marinum_M RRYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATAT------TYTMWE MUL_3201|M.ulcerans_Agy99 RRYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTAT------TYTMWE Mflv_2603|M.gilvum_PYR-GCK RLRCANGEPLALMTNHLPADIAPDAEELGNIGLYQALR------------ Mvan_4015|M.vanbaalenii_PYR-1 RLRCANGEPLALMTNYLPAEIAPDAEELESNGLYQSLR------------ MSMEG_4659|M.smegmatis_MC2_155 RLRSSNGQPLALMTNYLPAALAPDEDELARSGLYQSLR------------ MAB_0953|M.abscessus_ATCC_1997 RLRYADGVPLSVDTAYFPAELVPDLLEQPLGGSLYELC-----------Q TH_4188|M.thermoresistible__bu RRLHAG-APFVSTVVHLPDRAAHHLHGCAELRTGAVST----HTVIGLLE * . *: ::* Rv0792c|M.tuberculosis_H37Rv RRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPL Mb0816c|M.bovis_AF2122/97 RRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPL MAV_0738|M.avium_104 RRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLERTSYGHDDTPL MMAR_2560|M.marinum_M QRLGVRISSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPL MUL_3201|M.ulcerans_Agy99 QRLGVRISSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPL Mflv_2603|M.gilvum_PYR-GCK -ARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMARTAFDDSGAAV Mvan_4015|M.vanbaalenii_PYR-1 -ARGVHIRLARQRIGARSATRAEASLLDEKPNAPLLTMARTAFDDSGAAV MSMEG_4659|M.smegmatis_MC2_155 -ARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVMERTAFDDSGRIV MAB_0953|M.abscessus_ATCC_1997 VRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPF TH_4188|M.thermoresistible__bu PHLEEPIDQAAQSITVAPADDDTADAVGVEPGHPMLRIDRLYSDRTGRPV : : . * * :. *:* : * . . Rv0792c|M.tuberculosis_H37Rv EVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA-------------- Mb0816c|M.bovis_AF2122/97 EVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA-------------- MAV_0738|M.avium_104 EVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG---------------- MMAR_2560|M.marinum_M EVVLFHHRPERYEFCVTLPRTMPGQRAGMTER------------------ MUL_3201|M.ulcerans_Agy99 EVVLFHHRPERYEFCVTLPRTMPGQRAGMTER------------------ Mflv_2603|M.gilvum_PYR-GCK EFGNHCYRASRYYFDTTLVDR----------------------------- Mvan_4015|M.vanbaalenii_PYR-1 EFGNHCYRASRYYFDTTLVDR----------------------------- MSMEG_4659|M.smegmatis_MC2_155 EYGSHAYRASRYYFDTTLVDR----------------------------- MAB_0953|M.abscessus_ATCC_1997 EFSYDLFRADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDDTL TH_4188|M.thermoresistible__bu ELSVSHFLPEQYTYRVTLRRE----------------------------- * . ..: .*: Rv0792c|M.tuberculosis_H37Rv -- Mb0816c|M.bovis_AF2122/97 -- MAV_0738|M.avium_104 -- MMAR_2560|M.marinum_M -- MUL_3201|M.ulcerans_Agy99 -- Mflv_2603|M.gilvum_PYR-GCK -- Mvan_4015|M.vanbaalenii_PYR-1 -- MSMEG_4659|M.smegmatis_MC2_155 -- MAB_0953|M.abscessus_ATCC_1997 LA TH_4188|M.thermoresistible__bu --