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MEGCRVLQLGQIDRTDDKPPYRQIASMLREAISSSRFPPGERLPSEAELIEHFGVARMTVRQAMQELRSD GLVISQHGRGVFVRPTPPIRRLASDRFARQHRAEGKAAFSVEAEKSGYSPQVDNIAVSREKPNSFIAEQL RISADDDIVVRSRRYLANGRPVETAVSYIPAAFAEGTRIEQVDTGPGGIYARLEEHGHVLARFTEEVAAR MPTPEERRQLELDSGVPVLTVLRTAYDTNDVAVEVCDTVKVASAYLLEYEFPAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4842 | - | - | 100% (264) | regulatory protein |
| M. marinum M | MMAR_2560 | - | 4e-15 | 27.04% (233) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0304 | - | 1e-13 | 30.26% (228) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 4e-16 | 29.44% (231) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2603 | - | 5e-20 | 26.61% (248) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 4e-16 | 29.44% (231) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4644c | - | 2e-11 | 31.75% (126) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0738 | - | 2e-16 | 28.69% (237) | mercuric reductase/transcriptional regulator, fusion |
| M. smegmatis MC2 155 | MSMEG_4659 | - | 4e-22 | 27.02% (248) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3932 | - | 7e-16 | 28.94% (235) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_0525 | - | 1e-119 | 79.55% (264) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | 2e-22 | 30.80% (237) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4842|M.marinum_M -----MEGCRVLQLGQIDRTDDKPPYRQIASMLREAISSSRFPPGERLPS
MUL_0525|M.ulcerans_Agy99 -----MEGSQVLQLGQIDRADDKPPYRQIASMLRGAIISGELEAGGRLPS
Mb0816c|M.bovis_AF2122/97 ---MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPS
Rv0792c|M.tuberculosis_H37Rv ---MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPS
MAV_0738|M.avium_104 ---MVPDQLDLDAADLRISRGSVPASTQLAEALKAAIVKQRLPRGARLPT
Mflv_2603|M.gilvum_PYR-GCK --------MP--LTVELDRSSPVPLYYQLAQAIEAAIRDGELAPGDRFEN
MSMEG_4659|M.smegmatis_MC2_155 --------MTPTLSVELDRSSPVPLYFQVAQVFEKAILDGQLKPGDRFEN
Mvan_2288|M.vanbaalenii_PYR-1 MRVLTVDAAPLAARPDLVGSSDLPAHARIAQWLEALIASGDLIPGDKLPP
TH_3932|M.thermoresistible__bu ----MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIER-ARPGDRLPS
MAB_4644c|M.abscessus_ATCC_199 ---------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKLPG
. :::. : : . * ::
MMAR_4842|M.marinum_M EAELIEHFGVARMTVRQAMQELRSDGLVISQHG--RGVFVRPTPPIRRLA
MUL_0525|M.ulcerans_Agy99 EAELIEYFGVARMTVRQAVQELRTEGLVISEHG--RGVFVRPAPPIRWLA
Mb0816c|M.bovis_AF2122/97 ERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPV------
Rv0792c|M.tuberculosis_H37Rv ERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPV------
MAV_0738|M.avium_104 ERELVDRTRVSRVTVRAAVGLLERQGWLVRRQG--LGTFVANPV------
Mflv_2603|M.gilvum_PYR-GCK ELALAKRLTLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQNP-------
MSMEG_4659|M.smegmatis_MC2_155 ELALASRLNLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQTP-------
Mvan_2288|M.vanbaalenii_PYR-1 EVEIATSLGVSRMTLRQALSAVEAKGLIDRRRGRFGGNFVAAPR------
TH_3932|M.thermoresistible__bu EAELSGQFGVNRLTVRRALHELAQRGIIETVHG--RGSFVARQP------
MAB_4644c|M.abscessus_ATCC_199 EVALCEEFGVSRATVREAIRDLKTKGLVSTRQG--AGVFVTSDR------
* : : * * * *: : * : :* .*
MMAR_4842|M.marinum_M SDRFARQHRAEGKAAFSVEAEKSGYSPQVDNIAVSREKPNSFIAEQLRIS
MUL_0525|M.ulcerans_Agy99 SDRFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLRLT
Mb0816c|M.bovis_AF2122/97 -----EQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV
Rv0792c|M.tuberculosis_H37Rv -----EQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV
MAV_0738|M.avium_104 -----KQELGPGVRTITEVLAASGITPNVDVLSHRVEDAPQRIAETLHLT
Mflv_2603|M.gilvum_PYR-GCK ------VHRRVELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLA
MSMEG_4659|M.smegmatis_MC2_155 ------VHRPVELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIE
Mvan_2288|M.vanbaalenii_PYR-1 -----FEFDHASLPGFTEQMRRFEVEAGAQVLMATTGRPDAEVSRALGLR
TH_3932|M.thermoresistible__bu ---VRYRLSATRDASFTRGMRELGHPVRIEVLGAETTRCRRLRTELHTAG
MAB_4644c|M.abscessus_ATCC_199 -----PLGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIR
:
MMAR_4842|M.marinum_M ADDDIVVRSRRYLANGRPVETAVSYIPAAFAEGTRIEQVDTG--PGGIYA
MUL_0525|M.ulcerans_Agy99 ADDEVVVRSRRYLADGKPVETATSYIPVAFAQGTKIEQTDTG--PGGIYA
Mb0816c|M.bovis_AF2122/97 ---EVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSA--DTET--
Rv0792c|M.tuberculosis_H37Rv ---EVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSA--DTET--
MAV_0738|M.avium_104 ---KVLCVHRRFRDGEQPLALMIAYLPPGLGEAVEPLLKSAT--DTQTGR
Mflv_2603|M.gilvum_PYR-GCK EGREVASIQRLRCANGEPLALMTNHLPADIAP-DAEELGNIG--LYQA--
MSMEG_4659|M.smegmatis_MC2_155 PGSEIAYMRRLRSSNGQPLALMTNYLPAALAP-DEDELARSG--LYQS--
Mvan_2288|M.vanbaalenii_PYR-1 RTDQVHRILRARTANGEPIVLEEAYLPAAVFPGMLSKNLQAS--LYAL--
TH_3932|M.thermoresistible__bu ---EVLTTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSGSTSLFD----
MAB_4644c|M.abscessus_ATCC_199 ---RALVARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLD--------
:
MMAR_4842|M.marinum_M R--------LEEHGHVLARFTEEVAARMPTPEERRQLELDSGVPVLTVLR
MUL_0525|M.ulcerans_Agy99 R--------FEEAGHTLARFNEEVGARMPTPEERRALQLPPGAPVLTVVR
Mb0816c|M.bovis_AF2122/97 ----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDR
Rv0792c|M.tuberculosis_H37Rv ----TYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDR
MAV_0738|M.avium_104 AMESTYTMWERRLDTPIARASYEIHAAGASVEVAGALNLPLGSPVLVLER
Mflv_2603|M.gilvum_PYR-GCK ---------LRARGVHIRLARQRIGARSATRAEAHLLDEKPNAPLLTMAR
MSMEG_4659|M.smegmatis_MC2_155 ---------LRARGVHIRLARQRIGAKAADREEARLLDEKPKAPLLVMER
Mvan_2288|M.vanbaalenii_PYR-1 ---------MRGYGHAPCAADERIEATSATPEQARVLGVEPSCPLLLVVR
TH_3932|M.thermoresistible__bu -------FLWQTFGVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRG
MAB_4644c|M.abscessus_ATCC_199 ----------ELFDSFSVRMREAMLALLAGSAERP---HDQEHHQWLFDA
. . . * . .
MMAR_4842|M.marinum_M TAYDTNDVAVEVCDTVKVASAYLLEYEFPAR---------------
MUL_0525|M.ulcerans_Agy99 TAYDTKDVAVEVCDTVKVASAYLLEYDFSAR---------------
Mb0816c|M.bovis_AF2122/97 TSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
Rv0792c|M.tuberculosis_H37Rv TSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA
MAV_0738|M.avium_104 TSYGHDDTPLEVVEFHYRPERYRFSVTLPRTVPGPGAGIVERSG--
Mflv_2603|M.gilvum_PYR-GCK TAFDDSGAAVEFGNHCYRASRYYFDTTLVDR---------------
MSMEG_4659|M.smegmatis_MC2_155 TAFDDSGRIVEYGSHAYRASRYYFDTTLVDR---------------
Mvan_2288|M.vanbaalenii_PYR-1 TSFADNGVAVEFSRDYHRSDRTTIRIQSRADPVRQGY---------
TH_3932|M.thermoresistible__bu LNVDQHGAPVAVVRHRFRGDRVELTVDLA-----------------
MAB_4644c|M.abscessus_ATCC_199 IVDGSTRRAVELATDQLQHVRMR-----------------------
: