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M. thermoresistible (build 8) TH_4115 (-)

annotation: -
coordinates: 3978957 - 3979670
length: 238

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4115--100% (238)-
M. thermoresistible (build 8)TH_4408-1e-2131.67% (221) PUTATIVE regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_2873-2e-2132.88% (219) PUTATIVE regulatory protein GntR, HTH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3086c-2e-1027.73% (220) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_2114-3e-1630.14% (219) GntR domain-containing protein
M. tuberculosis H37RvRv3060c-2e-1027.73% (220) GntR family transcriptional regulator
M. leprae Br4923MLBr_01188-2e-0533.71% (89) hypothetical protein MLBr_01188
M. abscessus ATCC 19977MAB_4644c-2e-1733.94% (218) GntR family transcriptional regulator
M. marinum MMMAR_3975-7e-1833.33% (231) FadR family transcriptional regulator
M. avium 104MAV_2560-4e-2131.67% (221) regulatory protein GntR, HTH
M. smegmatis MC2 155MSMEG_0124-3e-1933.94% (221) transcriptional regulator, GntR family protein
M. ulcerans Agy99MUL_3832-2e-1833.77% (231) FadR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0952-2e-1630.77% (221) GntR domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAB_4644c|M.abscessus_ATCC_199      ----------------MHPRLSSQS-LAEQVANILAAQIGDGRWSTGAKL
Mvan_0952|M.vanbaalenii_PYR-1       ----------------MPLSTARRTGLVDQVIEQLRRAVAGGEWRVGERI
Mb3086c|M.bovis_AF2122/97           --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Rv3060c|M.tuberculosis_H37Rv        --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Mflv_2114|M.gilvum_PYR-GCK          MARSTPLAPMIGPDAVASRTAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MAV_2560|M.avium_104                ----------------MEVTSLREPKMADRVATVLRRMFIRGEITEGTML
MMAR_3975|M.marinum_M               --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99           --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MLBr_01188|M.leprae_Br4923          -------------------------------------------------M
TH_4115|M.thermoresistible__bu      -----------------------VQSSYIQVADQLRDLILRGDLAVGQKL
MSMEG_0124|M.smegmatis_MC2_155      ----------------------MSTSLAQRVVAGLKDKIFAGDLPPGHKL
                                                                                     :

MAB_4644c|M.abscessus_ATCC_199      PGEVALCEEFGVSRATVREAIRDLKTKGLVSTRQG--AGVFVTSDRP---
Mvan_0952|M.vanbaalenii_PYR-1       PNETVLVESLGVGRNTVREAVRALAHAGILEVRQG--DGTYVRATSE---
Mb3086c|M.bovis_AF2122/97           GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv        GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Mflv_2114|M.gilvum_PYR-GCK          PNEAELMAHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MAV_2560|M.avium_104                PPESELMERFGVSRPTLREAFRVLESESLIQVQRGVRGGARVTRPRRETL
MMAR_3975|M.marinum_M               PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99           PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MLBr_01188|M.leprae_Br4923          PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSA
TH_4115|M.thermoresistible__bu      PSEAEMAPLLGVSRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSERL
MSMEG_0124|M.smegmatis_MC2_155      PSEAELIDEFGVSRTVVREAVTRLRAEGLIETFQG-RGSFVLAVPEPTAF
                                      :  :   : *.   .***.  :    :    :*   .  :        

MAB_4644c|M.abscessus_ATCC_199      ------LGQWDRVLAAAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIR
Mvan_0952|M.vanbaalenii_PYR-1       ------VSGALRRLCGAELREVLQVRRALEVEGARLAAAHCTPADIAEMR
Mb3086c|M.bovis_AF2122/97           T----RAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPG-----
Rv3060c|M.tuberculosis_H37Rv        T----RAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPG-----
Mflv_2114|M.gilvum_PYR-GCK          A----RPAGLLLELSGATIADLLTAKSAIEPMAARLLAE--SGSAAAFDE
MAV_2560|M.avium_104                A----RYAGLILEYEGVTVKDVYDARVTLEVPMVEQLAK--DRNPKVIAE
MMAR_3975|M.marinum_M               A----YMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPE
MUL_3832|M.ulcerans_Agy99           A----YMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPE
MLBr_01188|M.leprae_Br4923          A----YMLGLLLQSKSIALADLGAALQELEPACAALAAQ-----------
TH_4115|M.thermoresistible__bu      EGMFNTSFSMLALTNQVDARSFLQAMRALEGPAAALAAAARGGDQ----V
MSMEG_0124|M.smegmatis_MC2_155      T------IESAAIRTQRDVLDMVDFRLGVECEAAALAAARIDARG----R
                                                         .      :*   .   *            

MAB_4644c|M.abscessus_ATCC_199      RALVARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMR
Mvan_0952|M.vanbaalenii_PYR-1       TLLARRDECAATDDTDAFARTDAEFHLAVVRGSGNRTLTELYR----GLI
Mb3086c|M.bovis_AF2122/97           IERLRAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTK
Rv3060c|M.tuberculosis_H37Rv        IERLRAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTK
Mflv_2114|M.gilvum_PYR-GCK          LEQLLEELVADSHQSPRLAEATGAFHLRVVQLSGNATLSIVAGMLHEITV
MAV_2560|M.avium_104                LEQIVERESQLNPGSEAVDQLT-DFHAAIARLSGNSTLQIVSDMLHHIIE
MMAR_3975|M.marinum_M               LKRVNEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWT
MUL_3832|M.ulcerans_Agy99           LKRVNEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWT
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      EELKRTAAMVDPADQEAAMQQSADFHSAILRASGNKLLEAMGRPVSAVAR
MSMEG_0124|M.smegmatis_MC2_155      DAVRTALDEFVGAAPEDAVEADFRFHRTIAEVSGNRFYLDLLNSLGPMMI
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      EAMLALLAGSAE---------RPHDQEHHQWLFDAIVDGSTRRAVELATD
Mvan_0952|M.vanbaalenii_PYR-1       EVVTASVATTRH---------VPVEMVDHGVLVDQIAAGDAEQAARTAGE
Mb3086c|M.bovis_AF2122/97           RYVQKSGTQSAG----EAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSER
Rv3060c|M.tuberculosis_H37Rv        RYVQKSGTQSAG----EAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSER
Mflv_2114|M.gilvum_PYR-GCK          RHTAFVFNERRP----VSKADYETLLRSYRRLLQFLRSRDADGAEAHWRR
MAV_2560|M.avium_104                KANRSLQPTKGT----RAEQAVRRSAKTHRMVLDMIKEGDAEKAGELWKR
MMAR_3975|M.marinum_M               SHEQQWADESAARGTYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIAGR
MUL_3832|M.ulcerans_Agy99           SHEQQWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGR
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      SKFRRTVPGLEF---------WERNQRAHQELLKAILAGDENLAYELATR
MSMEG_0124|M.smegmatis_MC2_155      MLPRTRLGDAHS---ITDAAHAERVRREHDQVAAAVAAGDPDLARAAMRL
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      QLQHVRMR------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1       LLDRILAGVDSADSC-----------------------------------
Mb3086c|M.bovis_AF2122/97           HVEAVAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAA
Rv3060c|M.tuberculosis_H37Rv        HVEAVAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAA
Mflv_2114|M.gilvum_PYR-GCK          HLDKTRELLLAGLESVPVRDVMG---------------------------
MAV_2560|M.avium_104                HLQKAEEFVLTGAELSTVVDLLE---------------------------
MMAR_3975|M.marinum_M               HLADTQTYVLSGRAEQRIYALSPQALSRPRDMRRP---------------
MUL_3832|M.ulcerans_Agy99           HLADTQTYVLSGRAEQRIYALSPQALSRPRDMRRP---------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      HIDEDLSPYYLPPEEADRDGAGA---------------------------
MSMEG_0124|M.smegmatis_MC2_155      HLGNTRRRLAGDR-------------------------------------
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           TIGDDIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMR
Rv3060c|M.tuberculosis_H37Rv        TIGDDIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMR
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0124|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           RGPGGGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKV
Rv3060c|M.tuberculosis_H37Rv        RGPGGGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKV
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0124|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           VKRRSEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTM
Rv3060c|M.tuberculosis_H37Rv        VKRRSEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTM
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0124|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
Mvan_0952|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           LDLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSL
Rv3060c|M.tuberculosis_H37Rv        LDLFLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSL
Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
MAV_2560|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
TH_4115|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0124|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAB_4644c|M.abscessus_ATCC_199      -----------------
Mvan_0952|M.vanbaalenii_PYR-1       -----------------
Mb3086c|M.bovis_AF2122/97           ARCRTRRHLDAAASWWL
Rv3060c|M.tuberculosis_H37Rv        ARCRTRRHLDAAASWWL
Mflv_2114|M.gilvum_PYR-GCK          -----------------
MAV_2560|M.avium_104                -----------------
MMAR_3975|M.marinum_M               -----------------
MUL_3832|M.ulcerans_Agy99           -----------------
MLBr_01188|M.leprae_Br4923          -----------------
TH_4115|M.thermoresistible__bu      -----------------
MSMEG_0124|M.smegmatis_MC2_155      -----------------