For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VQQRSDKAGPVTAAAGVPLHRQLFLVLHDEIDRGVIAPGEALPTEQTLCDQFGVSRITVRRALADLAAQG YIERRQGVGSFVRQHDPADVPTGRSYLQGLRQTQFETEAEVVELGVRSAPRAVAEALGRSGELLHIVRVR RQRRTREPLMVTDAWLPPELAPVLTERALRRAPLYELLSANGVAVDRVRHEITAEIAGPRNAQLLDVPIG AALLRVNRLVYVGDRPHHHVSALLSPSRSRVLLSQSADDMETGDGLRIAHDVGGPRG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1744 | - | - | 100% (267) | transcriptional regulator, GntR family protein |
| M. avium 104 | MAV_0738 | - | 6e-16 | 30.28% (251) | mercuric reductase/transcriptional regulator, fusion |
| M. avium 104 | MAV_3402 | - | 3e-10 | 32.29% (192) | GntR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 5e-20 | 31.11% (225) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2603 | - | 6e-14 | 30.10% (206) | UbiC transcription regulator-associated domain-containing |
| M. tuberculosis H37Rv | Rv0792c | - | 5e-20 | 31.11% (225) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 9e-15 | 33.33% (225) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2560 | - | 3e-22 | 35.02% (217) | GntR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4659 | - | 2e-17 | 32.86% (210) | GntR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3932 | - | 1e-13 | 31.73% (208) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3201 | - | 2e-22 | 34.56% (217) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2288 | - | 7e-17 | 30.56% (216) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
Rv0792c|M.tuberculosis_H37Rv MTS----VKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLP
MMAR_2560|M.marinum_M MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
MUL_3201|M.ulcerans_Agy99 MTSDEDSPRHDLADADLRVTRGSVPASVQLAELLRTQILERALSPGSRLP
Mflv_2603|M.gilvum_PYR-GCK --------MP--LTVELDRS-SPVPLYYQLAQAIEAAIRDGELAPGDRFE
MSMEG_4659|M.smegmatis_MC2_155 --------MTPTLSVELDRS-SPVPLYFQVAQVFEKAILDGQLKPGDRFE
Mvan_2288|M.vanbaalenii_PYR-1 MRVLTVDAAPLAARPDLVGS-SDLPAHARIAQWLEALIASGDLIPGDKLP
MAB_0953|M.abscessus_ATCC_1997 -----------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRLG
MAV_1744|M.avium_104 -------MQQRSDKAGPVTAAAGVPLHRQLFLVLHDEIDRGVIAPGEALP
TH_3932|M.thermoresistible__bu -----MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERAR-PGDRLP
* : : : * :
Mb0816c|M.bovis_AF2122/97 SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
Rv0792c|M.tuberculosis_H37Rv SERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQG--LGTFVADPVEQELS
MMAR_2560|M.marinum_M TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVKQDLE
MUL_3201|M.ulcerans_Agy99 TEQELIARSGVSRSTVRAAVGILEDEGWLVRRQG--LGTFVAEPVEQDLE
Mflv_2603|M.gilvum_PYR-GCK NELALAKRLTLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQNP--VHRR
MSMEG_4659|M.smegmatis_MC2_155 NELALASRLNLSRPTTRRAIQELVDKGLLVRKRG-VGTQVVQTP--VHRP
Mvan_2288|M.vanbaalenii_PYR-1 PEVEIATSLGVSRMTLRQALSAVEAKGLIDRRRGRFGGNFVAAPRFEFDH
MAB_0953|M.abscessus_ATCC_1997 SEREMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRADVVQRNV
MAV_1744|M.avium_104 TEQTLCDQFGVSRITVRRALADLAAQGYIERRQG--VGSFVRQHDPADVP
TH_3932|M.thermoresistible__bu SEAELSGQFGVNRLTVRRALHELAQRGIIETVHGRGSFVARQPVRYRLSA
* : :.* * * *: : * : *
Mb0816c|M.bovis_AF2122/97 CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIRR
Rv0792c|M.tuberculosis_H37Rv CGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLV---EVLCIRR
MMAR_2560|M.marinum_M SGVRTITEVLLSRGVTPRVEVLSHAVVAAPQSVGAALGRS---EVLRIQR
MUL_3201|M.ulcerans_Agy99 SGVRTITEVLLSRGVTPRVEVLAHAVVAAPQSVGAALGRS---EVLRIQR
Mflv_2603|M.gilvum_PYR-GCK VELTSLFDDLARAGQEPTTRLLKYHIGPPDEDVARELNLAEGREVASIQR
MSMEG_4659|M.smegmatis_MC2_155 VELTSLYDDLARAGQEPATEVLEYTRRPAQADIAERLSIEPGSEIAYMRR
Mvan_2288|M.vanbaalenii_PYR-1 ASLPGFTEQMRRFEVEAGAQVLMATTGRPDAEVSRALGLRRTDQVHRILR
MAB_0953|M.abscessus_ATCC_1997 AELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEGAEVFDVRR
MAV_1744|M.avium_104 TGR-SYLQGLRQTQFETEAEVVELGVRSAPRAVAEALGRSGELLHIVRVR
TH_3932|M.thermoresistible__bu TRDASFTRGMRELGHPVRIEVLGAETTRCRRLRTELHTAG---EVLTTTT
: ::
Mb0816c|M.bovis_AF2122/97 RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
Rv0792c|M.tuberculosis_H37Rv RIRTGDQPLALVTAYLPPGVG-PAVEPLLSGSADTETTYAMWERRLGVRI
MMAR_2560|M.marinum_M RYSESDQPLAIVTCYLPADLPHDAVEPLLSATSATATTYTMWEQRLGVRI
MUL_3201|M.ulcerans_Agy99 RYSESDQPLAIVTCYLPTDLPHDAVEPLLSATSVTATTYTMWEQRLGVRI
Mflv_2603|M.gilvum_PYR-GCK LRCANGEPLALMTNHLPADIAP-DAEELGNIG------LYQALRARGVHI
MSMEG_4659|M.smegmatis_MC2_155 LRSSNGQPLALMTNYLPAALAP-DEDELARSG------LYQSLRARGVHI
Mvan_2288|M.vanbaalenii_PYR-1 ARTANGEPIVLEEAYLPAAVFPGMLSKNLQAS------LYALMRGYGHAP
MAB_0953|M.abscessus_ATCC_1997 LRYADGVPLSVDTAYFPAELVPDLLEQPLGGS-----LYELCQVRYGLQA
MAV_1744|M.avium_104 RQRRTREPLMVTDAWLPPELAPVLTERALRRAP-----LYELLSANGVAV
TH_3932|M.thermoresistible__bu LRHVDGQPWSVSVTSIALDRFPGIAQQWSGSTS----LFDFLWQTFGVRM
* : :. . *
Mb0816c|M.bovis_AF2122/97 AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
Rv0792c|M.tuberculosis_H37Rv AQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHH
MMAR_2560|M.marinum_M SSATHEIQAAGASPEIAAALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
MUL_3201|M.ulcerans_Agy99 SSATHEVQAAGASPEIASALGLSEGAPVLVLRRTSYTDGDKPLEVVLFHH
Mflv_2603|M.gilvum_PYR-GCK RLARQRIGARSATRAEAHLLDEKPNAPLLTMARTAFDDSGAAVEFGNHCY
MSMEG_4659|M.smegmatis_MC2_155 RLARQRIGAKAADREEARLLDEKPKAPLLVMERTAFDDSGRIVEYGSHAY
Mvan_2288|M.vanbaalenii_PYR-1 CAADERIEATSATPEQARVLGVEPSCPLLLVVRTSFADNGVAVEFSRDYH
MAB_0953|M.abscessus_ATCC_1997 DSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPFEFSYDLF
MAV_1744|M.avium_104 DRVRHEITAEIAGPRNAQLLDVPIGAALLRVNRLVYVGD-RPHHHVSALL
TH_3932|M.thermoresistible__bu RRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPVAVVRHRF
. . . * * *. .:* :
Mb0816c|M.bovis_AF2122/97 RPERYQFSVTLPRTLPGSGAGIIEKRDFA----------------
Rv0792c|M.tuberculosis_H37Rv RPERYQFSVTLPRTLPGSGAGIIEKRDFA----------------
MMAR_2560|M.marinum_M RPERYEFCVTLPRTMPGQRAGMTER--------------------
MUL_3201|M.ulcerans_Agy99 RPERYEFCVTLPRTMPGQRAGMTER--------------------
Mflv_2603|M.gilvum_PYR-GCK RASRYYFDTTLVDR-------------------------------
MSMEG_4659|M.smegmatis_MC2_155 RASRYYFDTTLVDR-------------------------------
Mvan_2288|M.vanbaalenii_PYR-1 RSDRTTIRIQSRADPVRQGY-------------------------
MAB_0953|M.abscessus_ATCC_1997 RADRVRLTATMTSAVAQESRGVDGKVERVVSRLAAHRRPDDTLLA
MAV_1744|M.avium_104 SPSRSRVLLSQSADDMETGDGLRIAHDVGGPRG------------
TH_3932|M.thermoresistible__bu RGDRVELTVDLA---------------------------------
.* .