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VEPIWRRRGGPVPTQTEDLRRRIVADINAGKPGTKLGSERELAERYRTSRSSLRQVLAALEEAGLVDRVI GRSGGIFISHAQVQRSLTDVVGVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGIAADDFVIEIQRLRL ADGSPISLELAQFPAEAFPGLLEQQLGGSLYEILESEYGLVTARADERIEAVNATPEEANLLGIKPRSAL LLITRIAYDQHDTPCEFSRDLFRGDRTRLAVTAQGRGVGASPSVAAASVALHGPLAKAPSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1234 | - | - | 100% (272) | UbiC transcription regulator-associated domain-containing protein |
| M. gilvum PYR-GCK | Mflv_2652 | - | 3e-24 | 33.49% (215) | regulatory protein GntR, HTH |
| M. gilvum PYR-GCK | Mflv_2603 | - | 5e-19 | 32.76% (232) | UbiC transcription regulator-associated domain-containing |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0816c | - | 8e-12 | 28.03% (239) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0792c | - | 8e-12 | 28.03% (239) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0953 | - | 2e-52 | 44.27% (262) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4842 | - | 1e-15 | 30.62% (209) | regulatory protein |
| M. avium 104 | MAV_5032 | - | 4e-17 | 28.82% (229) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0268 | - | 1e-104 | 75.29% (255) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3932 | - | 1e-17 | 28.70% (216) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_0525 | - | 8e-15 | 30.29% (208) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5574 | - | 1e-128 | 92.89% (253) | UbiC transcription regulator-associated domain-containing |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0816c|M.bovis_AF2122/97 -MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSER
Rv0792c|M.tuberculosis_H37Rv -MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSER
MMAR_4842|M.marinum_M MEGCRVLQLGQIDRTDDK---PPYRQIASMLREAISSSRFPPGERLPSEA
MUL_0525|M.ulcerans_Agy99 MEGSQVLQLGQIDRADDK---PPYRQIASMLRGAIISGELEAGGRLPSEA
Mflv_1234|M.gilvum_PYR-GCK -------MVEPIWRRRGGPVPTQTEDLRRRIVADINAGK--PGTKLGSER
Mvan_5574|M.vanbaalenii_PYR-1 -------------------MPTQTEDLRRRIVSDINAGV--PGTKLGSER
MSMEG_0268|M.smegmatis_MC2_155 -------------------MPVQSEELRRRLVADINAGT--PGAKLGSER
MAB_0953|M.abscessus_ATCC_1997 --------------MEESEGGPVAEDVRRRILSMLAQGTLHPGSRLGSER
MAV_5032|M.avium_104 -------------------------MLRSQILEGAYGGLAAARPALPSES
TH_3932|M.thermoresistible__bu --MTRTATPMRSTTINRFADRPLYRQLSEVLEARLIERAR-PGDRLPSEA
: : * **
Mb0816c|M.bovis_AF2122/97 ELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGL--GTFVADP---------
Rv0792c|M.tuberculosis_H37Rv ELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGL--GTFVADP---------
MMAR_4842|M.marinum_M ELIEHFGVARMTVRQAMQELRSDGLVISQHGR--GVFVRPTPPIRRLASD
MUL_0525|M.ulcerans_Agy99 ELIEYFGVARMTVRQAVQELRTEGLVISEHGR--GVFVRPAPPIRWLASD
Mflv_1234|M.gilvum_PYR-GCK ELAERYRTSRSSLRQVLAALEEAGLVDRVIGRSGGIFISHA---------
Mvan_5574|M.vanbaalenii_PYR-1 ELAERYRTSRSSLRQVLAALEEAGLVDRVIGRAGGIFISHA---------
MSMEG_0268|M.smegmatis_MC2_155 DLAEKYGTSRSSLRQVLAALEEAGLVHRVIGRSGGIFISHG---------
MAB_0953|M.abscessus_ATCC_1997 EMAERFAVSRATVRSALVPLSRAGILERQTGRGGGTFVRAD---------
MAV_5032|M.avium_104 ALAAELGVSRNAIREALELLRGEGLITRVQGS--GTFVTGA---------
TH_3932|M.thermoresistible__bu ELSGQFGVNRLTVRRALHELAQRGIIETVHGR--GSFVARQP--------
: * ::* .: * * : * * *:
Mb0816c|M.bovis_AF2122/97 --VEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL---
Rv0792c|M.tuberculosis_H37Rv --VEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGL---
MMAR_4842|M.marinum_M RFARQHRAEGKAAFSVEAEKSGYSPQVDNIAVSREKPNSFIAEQLRISAD
MUL_0525|M.ulcerans_Agy99 RFARQHRANGKAAFTVEAERSGHTPQVDNITVSREKPDSVVAERLRLTAD
Mflv_1234|M.gilvum_PYR-GCK --QVQRSLTDVVGVPAFLASQGYVAGTRVLSTKMTAPDATTQQALGIAAD
Mvan_5574|M.vanbaalenii_PYR-1 --QVQRSLTDVVGVPAFLASQGYVAGTRVLSTKICAPDSATQQALKIGAD
MSMEG_0268|M.smegmatis_MC2_155 --QVERNLSDVVGVPAFLANQGYVAGTRILSTRITTPDQTTRTALRLGPG
MAB_0953|M.abscessus_ATCC_1997 --VVQRNVAELVGLPTRLHIGGHTSDTRVLGTSRRPATAAERAALEIAEG
MAV_5032|M.avium_104 --KLRQDLNRLKGLAESLAGHRLPVENKVLSIRESTATPFVAAKLQLPEN
TH_3932|M.thermoresistible__bu -VRYRLSATRDASFTRGMRELGHPVRIEVLGAETTRCR---RLRTELHTA
. .. : :
Mb0816c|M.bovis_AF2122/97 VEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAMWE
Rv0792c|M.tuberculosis_H37Rv VEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAMWE
MMAR_4842|M.marinum_M DDIVVRSRRYLANGRPVETAVSYIPAAFAEGTR-IEQVDTGPGGIYARLE
MUL_0525|M.ulcerans_Agy99 DEVVVRSRRYLADGKPVETATSYIPVAFAQGTK-IEQTDTGPGGIYARFE
Mflv_1234|M.gilvum_PYR-GCK DFVIEIQRLRLADGSPISLELAQFPAEAFPGLLEQQLG----GSLYEILE
Mvan_5574|M.vanbaalenii_PYR-1 DFVIEIQRLRLADGSPISLELAQFPADAFPGLLEQQLG----GSLYEILE
MSMEG_0268|M.smegmatis_MC2_155 EYVVEIQRVRLADGSPISLEQAQFPAEKFPGLLEQQLG----GSLYEVLE
MAB_0953|M.abscessus_ATCC_1997 AEVFDVRRLRYADGVPLSVDTAYFPAELVPDLLEQPLG----GSLYELCQ
MAV_5032|M.avium_104 APILFIERLRSVGGLPLSLDTTSLRIGAIRIDADLDKQ-----DVFALIE
TH_3932|M.thermoresistible__bu GEVLTTTTLRHVDGQPWSVSVTSIALDRFPGIAQQWSG---STSLFDFLW
:. ... * : : :
Mb0816c|M.bovis_AF2122/97 RRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPL
Rv0792c|M.tuberculosis_H37Rv RRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPL
MMAR_4842|M.marinum_M EHG-HVLARFTEEVAARMPTPEERRQLELDSGVPVLTVLRTAYDTNDVAV
MUL_0525|M.ulcerans_Agy99 EAG-HTLARFNEEVGARMPTPEERRALQLPPGAPVLTVVRTAYDTKDVAV
Mflv_1234|M.gilvum_PYR-GCK SEYGLVTARADERIEAVNATPEEANLLGIKPRSALLLITRIAYDQHDTPC
Mvan_5574|M.vanbaalenii_PYR-1 SQYGLVTARADERIEAVNATPEEANLLGIKAKSALLLITRITYDQHDTPC
MSMEG_0268|M.smegmatis_MC2_155 SQYGLVPGRADERIEAVNATSNEATLLGIKPKAALLLITRVTFDQTGTPY
MAB_0953|M.abscessus_ATCC_1997 VRYGLQADSSTETIEVVSANPREAEWLDVPHRRPLLAITRVTRNTDGRPF
MAV_5032|M.avium_104 QELGERLGWAEITVESVLADPNTATLLQIRTGAPLLLLHRLTHLRDGTPF
TH_3932|M.thermoresistible__bu QTFGVRMRRAYRSFSAVLADLAEAQHLGLRTGAPVLEMRGLNVDQHGAPV
. . * : .:* : . .
Mb0816c|M.bovis_AF2122/97 EVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA--------------
Rv0792c|M.tuberculosis_H37Rv EVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA--------------
MMAR_4842|M.marinum_M EVCDTVKVASAYLLEYEFPAR-----------------------------
MUL_0525|M.ulcerans_Agy99 EVCDTVKVASAYLLEYDFSAR-----------------------------
Mflv_1234|M.gilvum_PYR-GCK EFSRDLFRGDRTRL------AVTAQGRGVGASPS----VAAASVALHGPL
Mvan_5574|M.vanbaalenii_PYR-1 EFSRDLFRGDRTRL------AVTAQGRGVGVQPS----VAAASVALQSPP
MSMEG_0268|M.smegmatis_MC2_155 EFSRDLFRGDRTAL------AVTAKGRGIAAASNSGTDNRTASVTLHRQV
MAB_0953|M.abscessus_ATCC_1997 EFSYDLFRADRVRLTATMTSAVAQESRGVDGKVER----VVSRLAAHRRP
MAV_5032|M.avium_104 DLETVRYRGDRCSLVTTATREDAPPQ------------------------
TH_3932|M.thermoresistible__bu AVVRHRFRGDRVELTVDLA-------------------------------
. . :
Mb0816c|M.bovis_AF2122/97 ------
Rv0792c|M.tuberculosis_H37Rv ------
MMAR_4842|M.marinum_M ------
MUL_0525|M.ulcerans_Agy99 ------
Mflv_1234|M.gilvum_PYR-GCK AKAPSA
Mvan_5574|M.vanbaalenii_PYR-1 I-----
MSMEG_0268|M.smegmatis_MC2_155 G-----
MAB_0953|M.abscessus_ATCC_1997 DDTLLA
MAV_5032|M.avium_104 ------
TH_3932|M.thermoresistible__bu ------