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RALLAQNRLVTLCGTGGVGKTRLAIQIASASELRDGLCFVDLAPITESGIVAATAARAVGLPDQPGRSTM DSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPELTILATSREPIGMAGEITWRVPSMSITDEAV ELFADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLEIADGLDDCFRLLAGGVRG AVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVDKSLVV ADDCQGRTRYRLLETVRRYALEKLGDSGEADVHARHRDYYTALAASLNTPADNDHQRLVARAETEIDNLR AAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLST WLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATDLARAIDDKWTL CQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEALELSREITAE AEASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAALE ASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATNGWHRMVALTIRARVATARGEPE LARDDAHAALACGAELHIYQGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIWDAGYQA SVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDI AKRLFVSPRTVQTHLTHVYAKLGLPSRVQLVDEAARRGSPS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv0890c | - | - | 100% (882) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR-FAMILY) |
M. tuberculosis H37Rv | Rv1358 | - | 0.0 | 65.50% (884) | transcriptional regulatory protein |
M. tuberculosis H37Rv | Rv0386 | - | 0.0 | 57.01% (884) | LuxR/UHPA family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0914c | - | 0.0 | 99.89% (882) | LuxR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_1156 | - | 6e-16 | 25.25% (495) | regulatory protein, LuxR |
M. leprae Br4923 | MLBr_01753 | - | 0.0 | 59.89% (880) | putative transcriptional regulator |
M. abscessus ATCC 19977 | MAB_0060 | - | 2e-09 | 43.48% (69) | nitrate/nitrite response transcriptional regulatory protein |
M. marinum M | MMAR_0123 | - | 0.0 | 52.13% (890) | LuxR family transcriptional regulator |
M. avium 104 | MAV_0578 | - | 5e-16 | 24.54% (925) | transcriptional regulator, LuxR family protein |
M. smegmatis MC2 155 | MSMEG_4431 | - | 8e-17 | 25.64% (429) | putative regulatory protein |
M. thermoresistible (build 8) | TH_3225 | - | 1e-10 | 25.08% (630) | PUTATIVE regulatory protein, LuxR |
M. ulcerans Agy99 | MUL_2743 | - | 5e-73 | 35.18% (597) | LuxR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_5928 | - | 0.0 | 55.90% (882) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment Rv0890c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0914c|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG MMAR_0123|M.marinum_M --MLASMSEIDPRAEAPLVDWSDVDMG------ELLPTGTVTLLLADVEG Mvan_5928|M.vanbaalenii_PYR-1 -------------------------MS------ELVPTGTVTLLLADVQG MUL_2743|M.ulcerans_Agy99 ----------------------------------------MTFLFTDVEG MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 -------------------------------------------------- MSMEG_4431|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1156|M.gilvum_PYR-GCK -------------------------------------------------- TH_3225|M.thermoresistible__bu -------------------------------------------------- Rv0890c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0914c|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR MMAR_0123|M.marinum_M STRLWQNQPEPMTAAVAHLDSVLATTVATHHGVRPVEQGEGDSFVVAFAS Mvan_5928|M.vanbaalenii_PYR-1 STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR MUL_2743|M.ulcerans_Agy99 STRLWESDPDRMRAALAAHDAVLTRTIQTHRGWLFKHTGDG--VCAAFAS MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 -------------------------------------------------- MSMEG_4431|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1156|M.gilvum_PYR-GCK -------------------------------------------------- TH_3225|M.thermoresistible__bu -------------------------------------------------- Rv0890c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0914c|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDV--NNVVFMMVQAA MMAR_0123|M.marinum_M AREAIACALDLQRSPLGPIRLRIGVHTGDIQLRDPNDPTNYIGPTINRTA Mvan_5928|M.vanbaalenii_PYR-1 ASDAVACALALQRAPLAPIRLRIGVHTGEVRLRDEG---NYVGPTINRTA MUL_2743|M.ulcerans_Agy99 PRSAVDAAVDAQRALELPVRMGLATG------EAEPHDADYFGAVLNRAA MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 -------------------------------------------------- MSMEG_4431|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1156|M.gilvum_PYR-GCK -------------------------------------------------- TH_3225|M.thermoresistible__bu -------------------------------------------------- Rv0890c|M.tuberculosis_H37Rv -------------------------------------------------- Mb0914c|M.bovis_AF2122/97 -------------------------------------------------- MLBr_01753|M.leprae_Br4923 GLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQ MMAR_0123|M.marinum_M RIRELAHGGQTVISGATQLLVVDQLPDGAWLADLGLHPLRDLPRPERVMQ Mvan_5928|M.vanbaalenii_PYR-1 RLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQ MUL_2743|M.ulcerans_Agy99 RVMATGHGGQILLTDSTANLIS-----GVDLLDLGSRRLRDLPAPVRVFQ MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 -------------------------------------------------- MSMEG_4431|M.smegmatis_MC2_155 -------------------------------------------------- Mflv_1156|M.gilvum_PYR-GCK -------------------------------------------------- TH_3225|M.thermoresistible__bu -------------------------------------------------- Rv0890c|M.tuberculosis_H37Rv ----------------------------------------MRALLAQNR- Mb0914c|M.bovis_AF2122/97 ----------------------------------------MRALLAQNR- MLBr_01753|M.leprae_Br4923 LCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKR- MMAR_0123|M.marinum_M LCHSGLQNDFPPLRTTKSIAVHRMPARLTRFVGRIAQMADVRSLLADNR- Mvan_5928|M.vanbaalenii_PYR-1 LCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANR- MUL_2743|M.ulcerans_Agy99 VRAPGLRTDFPALRAPDTSPG-NLRPALTSFVARAAEIGQVQTALQVHR- MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 ---------------------MIGGELLIGRDSELAAIRRALNGADHHR- MSMEG_4431|M.smegmatis_MC2_155 MNRRQDTPVGPSTDFFDVGGERLITPPIRGRADELKTAGALITAAARGRG Mflv_1156|M.gilvum_PYR-GCK -----MKAVDDFLAGLQQLQPAGLLIEGEAGIGKTTMLAGVVDAARQAG- TH_3225|M.thermoresistible__bu ------------------MSSRDGDVVLHGRAAEIATLRDVMSTARAGSS Rv0890c|M.tuberculosis_H37Rv -LVTLCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATA Mb0914c|M.bovis_AF2122/97 -LVTLCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATA MLBr_01753|M.leprae_Br4923 -LLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT- MMAR_0123|M.marinum_M -LVTLTGAGGAGKTRLAVEIAASAVDEFGDGLWYVDLAPVSHAEAVPVTV Mvan_5928|M.vanbaalenii_PYR-1 -LVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAITV MUL_2743|M.ulcerans_Agy99 -LVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDAV MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 -GVVIAGAAGVGKTWLARAALRR-AGASGEQIKWIVGTQSAQALPLGAFI MSMEG_4431|M.smegmatis_MC2_155 GVLVIEGPPGIGKSRLLTEVLG---LADKCGVRTLFGEAFEYQQTVPFFS Mflv_1156|M.gilvum_PYR-GCK -FRVLSAHGDQSGSGLAHAAIADLFAGVQTDILDGLPELQRRAADGVLRR TH_3225|M.thermoresistible__bu RVLVLHGEAGVGKTALLGQLLGDAAGMRCVQVAGVESDMELAYAGLHQLC Rv0890c|M.tuberculosis_H37Rv ARAVGLPDQPGRSTMDSLRRFIGNRR-----MLMVLDNCEHLLDACAA-- Mb0914c|M.bovis_AF2122/97 ARAVGLPDQPGRSTMDSLRRFIGNRR-----MLMVLDNCEHLLDACAA-- MLBr_01753|M.leprae_Br4923 -------------VLDNLRRCIGDRR-----MLMVLDNCEYLLDVCAN-- MMAR_0123|M.marinum_M ARALGLSDQPGRSTVDALARFIGEHQ-----VLVVLDNCEHLLDATAA-- Mvan_5928|M.vanbaalenii_PYR-1 ARALGLPDQPGRSTVDTIVRFIADRR-----MLVVLDNCEHLLDACAT-- MUL_2743|M.ulcerans_Agy99 AAVLGITQQAGKTVTQSVATALERRV-----RLLVFDNCEHVRDAAAD-- MAB_0060|M.abscessus_ATCC_1997 ------------------------------------------MQVSGE-- MAV_0578|M.avium_104 GLLGDAMSEPLTSVRRVIETFVARQRR---GRVVVGVDDAHLLDGLSA-- MSMEG_4431|M.smegmatis_MC2_155 LFMATLRADPPIGDVAALRELGGSADL---RYWVVHDLHNAIRAAAAQTP Mflv_1156|M.gilvum_PYR-GCK GDGTGGPTDERVIAAALLGAVHGSATR---TPVLVAVDDVQWLDPSSVAV TH_3225|M.thermoresistible__bu APLLDRLDDLPSPQRDVLNVAFGRGAGPAPGRFLVGLAVLNLLAAAGADQ . Rv0890c|M.tuberculosis_H37Rv --LVVELLGACPELTILA----TSREPIGMAGEITWRVPSMSITD----- Mb0914c|M.bovis_AF2122/97 --LVVELLGACPELTILA----TSREPIGMAGEITWRVPSMSITD----- MLBr_01753|M.leprae_Br4923 --VMTTLLGACPSLTILA----TSREPIGVAGEVIWRVSMLSPAD----- MMAR_0123|M.marinum_M --LLLELTGRCPAVRLLA----TSREPLGVPGEVTFLVPSLSVT------ Mvan_5928|M.vanbaalenii_PYR-1 --LIDALLGACPALAMLA----TSREPIAVAGEQTWRVPPLALDD----- MUL_2743|M.ulcerans_Agy99 --LIEAILAGSTTVRILA----TSRERLEVPDEQLWSVPSLDVGGGV--V MAB_0060|M.abscessus_ATCC_1997 --LVRVVVGDDHPLFREG----VVR-ALTASGQITVVAEAENGTG----- MAV_0578|M.avium_104 --LVVHQLAQSGGVRLVV----TVRTGSHQPDAVTALWKDDLLTR----- MSMEG_4431|M.smegmatis_MC2_155 LMIVLEDIHWADNATLLA----LRSLTTEIDVPVLWVFTARTGAGGQ--A Mflv_1156|M.gilvum_PYR-GCK LAFVARRVKGRVGFVVAE----RPGVGPGLPAATWLQVGTGALTR----- TH_3225|M.thermoresistible__bu PLLCVIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRDDIHEALVGVP . Rv0890c|M.tuberculosis_H37Rv -EAVELFADRASRVQPGFTIANH-NAAAVGEICRRLDGIPLAIEFAAARV Mb0914c|M.bovis_AF2122/97 -EAVELFADRASRVQPGFTIANH-NAAAVGEICRRLDGIPLAIEFAAARV MLBr_01753|M.leprae_Br4923 -EAVELFTERAALVQPGFSVTDG-NRQIVTEICQRLDGMPLAIELAAARI MMAR_0123|M.marinum_M -EATELFTDRARRVRPDFAVTDD-NTTAVTEICNRLDCMPLAIELAAARV Mvan_5928|M.vanbaalenii_PYR-1 -DAIELFTDRARRARPDFIISAD-DAAAVSEICHRLDGMPLAIELAAARV MUL_2743|M.ulcerans_Agy99 SAAGTLFVERAQSVAPGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRM MAB_0060|M.abscessus_ATCC_1997 --ALELIREHRP------------DVALVDYRMPELDGTQVAAAVRRDEL MAV_0578|M.avium_104 -LDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLSDQ MSMEG_4431|M.smegmatis_MC2_155 VQETLSVLQRTDATFLRLAAMTPDAVADMVQDAVRARADTSLLSLAAKAH Mflv_1156|M.gilvum_PYR-GCK -LPVAPMSLGALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALELARVA TH_3225|M.thermoresistible__bu ALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTY . Rv0890c|M.tuberculosis_H37Rv RS---MSPLEIADGLDDCFRLLAGGVRGA-VQRQQTLRASIDWSHALLTE Mb0914c|M.bovis_AF2122/97 RS---MSPLEIADGLDDCFRLLAGGVRGA-VQRQQTLRASIDWSHALLTE MLBr_01753|M.leprae_Br4923 RT---LSLTEIADGLDDRFRLLTGGARTA-VRRQQTLRASMDWSYALLTE MMAR_0123|M.marinum_M RA---LSIDEIRTGLHDRFRLLTGGARTV-VRRQQTLRASVDWSHALLTE Mvan_5928|M.vanbaalenii_PYR-1 RA---LSLTEIVDGLHDRFRLLTGGSRTA-VRRQQTLRASVDWSHGLLTD MUL_2743|M.ulcerans_Agy99 AS---MTPIEVRDRLDHRFRLLVG-SRRG-LGRHQTLRHAVAWSYDHLSD MAB_0060|M.abscessus_ATCC_1997 PTR--VLLLSAHDDAAIVYRALEEGAAGF-LSKE---------------S MAV_0578|M.avium_104 MAAGRMRRVAGVWMWDGDVAVSASLSDTV-GRQLGRLTPPLALVVDTLSQ MSMEG_4431|M.smegmatis_MC2_155 GNPFLISELVRGLGEEGRLGLSDGRAVASGFALPRRLGASMHQRLDLLSE Mflv_1156|M.gilvum_PYR-GCK DGAGSRPGQRLPESLSELVRLRVDGLAEDVRDVLLVAASATSPTVDLLAK TH_3225|M.thermoresistible__bu AVGELAGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGD . Rv0890c|M.tuberculosis_H37Rv TEQILFRRLAPFVGGFDLAAVRAVAA--GSDLDPFSVLDQLTLLVDKSLV Mb0914c|M.bovis_AF2122/97 TEQILFRRLAPFVGGFDLAAVRAVAA--GSDLDPFSVLDQLTLLVDKSLV MLBr_01753|M.leprae_Br4923 SERALFRRLSAISGTFDLKVAYAVGH--DDLEEPDQVFDRLTMLIDKSLV MMAR_0123|M.marinum_M PERVLFRRIAVFLGGFDLDAAQAVAG--DSQVQRYQVVDELALLVDKSLV Mvan_5928|M.vanbaalenii_PYR-1 PERVLFRRLAVFAGGFDLDGAQAITV--DGEVHRYEVVDLLTLLVDKSLL MUL_2743|M.ulcerans_Agy99 AEKVLLERCSVFAGGFDLQSACAVAGS-ADTHDDYEVLDLLDALVGKSLL MAB_0060|M.abscessus_ATCC_1997 TRTELVGAVLDCARGRDVVAASLTAG------------------------ MAV_0578|M.avium_104 CEPLPVDLLCDLASREDLVAAEAMGLV-TVERTPRALMARLAHP-----L MSMEG_4431|M.smegmatis_MC2_155 GASEVVRVAAVLPDRFTAGLLAAMLE-----RSPTSLLSSLEEAVHADLF Mflv_1156|M.gilvum_PYR-GCK AVGVTPAAVTGLVEAAEVEGIVVIDG----NRIRFTHPVLANGIYAGADP TH_3225|M.thermoresistible__bu SALFLRAAALMGIAVDALAPAEAARVIQFGPRMRFFHPLMRSAAYRAADP Rv0890c|M.tuberculosis_H37Rv VADDCQGRTRYRLLETVRRYALEKLGDSGEAD-VHARHRDYYTALAASLN Mb0914c|M.bovis_AF2122/97 VADDCQGRTRYRLLETVRRYALEKLGDSGEAD-VHARHRDYYTALAASLN MLBr_01753|M.leprae_Br4923 IVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLD MMAR_0123|M.marinum_M IAESGGGPTRYRLLETVRQYAQEKLAESGEVEAVRSRHVTYYKSVAKLLD Mvan_5928|M.vanbaalenii_PYR-1 IAENTAGRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELD MUL_2743|M.ulcerans_Agy99 IVDRLSGRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVA MAB_0060|M.abscessus_ATCC_1997 ------------LAGEIRKRAQP--------------------------A MAV_0578|M.avium_104 FGELRRAGAGEMYLSTIRGRLATRLAQDQDADMQATVRRALLTLESDLDP MSMEG_4431|M.smegmatis_MC2_155 IEDGEQLRFRHDLLREATRQSLPKSLRRAMERQSASVMLGMGAAPAEVAT Mflv_1156|M.gilvum_PYR-GCK QRRREVHRRLADLKTDPELRARHLALASTVADETTLTTLDAAADAARARG TH_3225|M.thermoresistible__bu RDRRAVHRALAEATDPGADPDRRAWHAANGVTGTDDAVAAELEKSAARAQ Rv0890c|M.tuberculosis_H37Rv TPADNDHQR-LVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWF Mb0914c|M.bovis_AF2122/97 TPADNDHQR-LVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWF MLBr_01753|M.leprae_Br4923 TPGDIDHEQ-LVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWF MMAR_0123|M.marinum_M APTGTDHER-RLAQAEDELDNLRSAFGWSLETRDFDSALELATSLHPVWM Mvan_5928|M.vanbaalenii_PYR-1 APSVAGHER-RLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWR MUL_2743|M.ulcerans_Agy99 AVWDSPRQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGF MAB_0060|M.abscessus_ATCC_1997 GPSLSTRER--------------------EVLRMIAAGQTVPAIARALFL MAV_0578|M.avium_104 QPELYLESA--RHAMTLLDLDLADRLANAAARAGAPGAAGVRAMNLVLLG MSMEG_4431|M.smegmatis_MC2_155 QLARSAEPG-DREAIDALREAAQAVGRGDAGAAADLSRCALELSPADDAE Mflv_1156|M.gilvum_PYR-GCK APAAAAELLEWAMQLGGDSVSRRIRAAEHHVVAGDMRRAATLLEQALVDL TH_3225|M.thermoresistible__bu QRGGIAATATFLERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLA Rv0890c|M.tuberculosis_H37Rv GRAHLREGLSWFNSILE---------DQRFHRLAVSTAVRARALADKAML Mb0914c|M.bovis_AF2122/97 GRAHLREGLSWFNSILE---------DQRFHRLAVSTAVRARALADKAML MLBr_01753|M.leprae_Br4923 GRGHMYEGLAWFDSIFE---------HKNIEHLVAPKEVLARAVANKVML MMAR_0123|M.marinum_M TRGQGREGLAWLEAGLGNEAGLGNEAGLGNEDVQVSPSTLARALADKVTL Mvan_5928|M.vanbaalenii_PYR-1 ARGRLQEGQAWFDAALT-----DYEARPG----EADPAVYARALADRAFM MUL_2743|M.ulcerans_Agy99 LVNR-FEPLTWVEEAIE--------------------------------- MAB_0060|M.abscessus_ATCC_1997 APSTVKTHVQRLYEKLG--------------------------------- MAV_0578|M.avium_104 RGEQAEEALRAITDGADG----------------DASDRHYWATVRAANL MSMEG_4431|M.smegmatis_MC2_155 HGSLIAETVGWLNRASRYG--------EAEELADMALADAASPEVEAEIR Mflv_1156|M.gilvum_PYR-GCK RPGVLCAIALNLLAGVR--------------------------------- TH_3225|M.thermoresistible__bu IAERAPLSALEWARAVHLR------------------AQLEFARSRAGDA Rv0890c|M.tuberculosis_H37Rv STWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAE Mb0914c|M.bovis_AF2122/97 STWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAE MLBr_01753|M.leprae_Br4923 HAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTE MMAR_0123|M.marinum_M LAWTG-----SMAGFDDAERALTIARELADPALLIRALVARGVITAYDAD Mvan_5928|M.vanbaalenii_PYR-1 DGHVG-----ITDRLDQAQKALAMARDIDDPALLVRALTACGGLAAYNAD MUL_2743|M.ulcerans_Agy99 -------------------------RAVDHPKLAFLHVLASQCYTTGRVQ MAB_0060|M.abscessus_ATCC_1997 ---------------------------VGDRAAAVAEAMRRGLLE----- MAV_0578|M.avium_104 VWMLG-------RPADAALVLDGLAARPETPAQAAARCAVQACLDAVAAR MSMEG_4431|M.smegmatis_MC2_155 LRLPTQTKHSSPQRVAESRRALRLRGISELTRARHLASLAYNLVLQDEDA Mflv_1156|M.gilvum_PYR-GCK --------MVEDDYIRAVELLERARADADNDAVLVTTLLSLGFCLGMTGS TH_3225|M.thermoresistible__bu GGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAPSGAL Rv0890c|M.tuberculosis_H37Rv AAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISG-DPNALRAAAEEC Mb0914c|M.bovis_AF2122/97 AAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISG-DPNALRAAAEEC MLBr_01753|M.leprae_Br4923 VARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAA MMAR_0123|M.marinum_M VARPYFDEAAQLARELGDSWRLSQILSLQTRAAMAAG-DPIALEAAGEEG Mvan_5928|M.vanbaalenii_PYR-1 VARPLLAEAVDLARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEA MUL_2743|M.ulcerans_Agy99 EAIRYADEAARLLAT--DRYEVPFGIEGWPSGACTSSGHPEQSVELCRTQ MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 CQLAAERARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQAL MSMEG_4431|M.smegmatis_MC2_155 QSRTAADEAAAAAASTGDPEAIIMAEVTHALLDSGEG-YAVRALRRLEQL Mflv_1156|M.gilvum_PYR-GCK FTAQLATVREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLRA TH_3225|M.thermoresistible__bu LEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAM Rv0890c|M.tuberculosis_H37Rv RDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEA---LELSREITAEAEAS Mb0914c|M.bovis_AF2122/97 RDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEA---LELSREITAEAEAS MLBr_01753|M.leprae_Br4923 DDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGA---IVRSGEVVAGAEAA MMAR_0123|M.marinum_M LRIAEAIGDRTTSRECRGALGWVRAWRGDPIGA---LHQLGEAIAEASAA Mvan_5928|M.vanbaalenii_PYR-1 RELADEMGDGFVSRICGWLLGIAHHFQGDLDAA---LALADGVVSESDVA MUL_2743|M.ulcerans_Agy99 LALGHDTHTLTLG-----CLVLALTIKGQCDEA---EQLADALIESAEAT MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 RRATTSFEASHMRFWFGAVYGRACRLTGRIDEF---VSTARRLADSARDV MSMEG_4431|M.smegmatis_MC2_155 RGIAYTNETALAHAYAGMFHANMLAVVGRLDDA---TNRAAEGIAQADRE Mflv_1156|M.gilvum_PYR-GCK VDLEDPEDNTPIPFRASAARGLSLALTGRLAEA---DGQLAAVAQRSAQR TH_3225|M.thermoresistible__bu CELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDA Rv0890c|M.tuberculosis_H37Rv NDVPTKVLGLYTQAQVLAYCG-ASAAHAIAGACI-AAATELGGVYQGIGY Mb0914c|M.bovis_AF2122/97 NDVPTKVLGLYTQAQVLAYCG-ASAAHAIAGACI-AAATELGGVYQGIGY MLBr_01753|M.leprae_Br4923 HDTVTRTFGLYVQTRALVHRD-VSAALVTAGLVV-EAAAELSGVYQGIGY MMAR_0123|M.marinum_M HDLLLLMISQVVQGFTYAYVGDADGACACADAVF-TSSAELVGANEGLGY Mvan_5928|M.vanbaalenii_PYR-1 HDTLNGCCGELVLAHSLAQRGDTDAARAAAQVSL-NVAVEVSPVHAGLAH MUL_2743|M.ulcerans_Agy99 RNPAALCYALLAYGFTFRDTN----------------------------- MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 PGLAYANLALLLGNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASY MSMEG_4431|M.smegmatis_MC2_155 RSAMVLDNWAVYAGWVHLAAGRLSAARGAAESLPPPQASGAQELDVHRML Mflv_1156|M.gilvum_PYR-GCK GAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMVIAFSI TH_3225|M.thermoresistible__bu GALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHR Rv0890c|M.tuberculosis_H37Rv AAMTYAALAAGDVTAALEA-SDAARPILRAQPDQVTMH-QVLMAQLALAG Mb0914c|M.bovis_AF2122/97 AAMTYAALAAGDVTAALEA-SDAARPILRAQPDQVTMH-QVLMAQLALAG MLBr_01753|M.leprae_Br4923 AAMVFAALAMGDVAAAVEA-SEACRPHLGADHGLVAIH-LELMAAVALAR MMAR_0123|M.marinum_M ATAAIACQAAGDATAAWKA-YQKARELVGMDPQMAGVFPFGALAPLVS-- Mvan_5928|M.vanbaalenii_PYR-1 AALAVANLAAGDVTAAEAA-SDSATRSFGPS-EVAGIQDPNVAAQIACTR MUL_2743|M.ulcerans_Agy99 PASALAAMRRGLRIAQDTG-NRNS-------------------------- MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 FALAEAHGRLGHPAQANEA-IAGARSCVPPDFLFMHTG------------ MSMEG_4431|M.smegmatis_MC2_155 ILAEVAAHSDDRNLLLETA-NDAHDAHCTGPPGQRRACAYVLARAAWYRG Mflv_1156|M.gilvum_PYR-GCK CAAVAAYRGREDQARDQAAGALAQGGDYVALTVWASATLAFLEVSRGNYE TH_3225|M.thermoresistible__bu LIIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNGIGRY Rv0890c|M.tuberculosis_H37Rv GDAIAARQFANDAVDATNGW-HRMVALTIRARVATARGEPELARDDAHAA Mb0914c|M.bovis_AF2122/97 GDAIAARQFANDAVDATNGW-HRMVALTIRARVATARGEPELARDDAHAA MLBr_01753|M.leprae_Br4923 GDVIVARRLADNSVSATTGW-HQMAALTTRARIAMAQGEPELARADIHAA MMAR_0123|M.marinum_M GDLSAARRWADDVVSTSYGC-YLSVALTARARVALAQGELGQADRDSHAA Mvan_5928|M.vanbaalenii_PYR-1 GDLDTARSLVDGAVSITRGV-HRASALTTRARIAIAQGDPEQAERNAHDA MUL_2743|M.ulcerans_Agy99 ----------------------ETHLAAVLCRVEAKYGDPLSALDHFTLA MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 ----LALATGWALAAGGQLR-EAVATAQAAARLARDRGQPTHELACIQAA MSMEG_4431|M.smegmatis_MC2_155 DIHEAARWLGDINLLGTPLFPHALVRLILAAQVASAAGDAGLRARVLQAA Mflv_1156|M.gilvum_PYR-GCK QALEAAEPLVDLYRDFPGTELMSACFMPDAIESLIAVGRLDEAEPLIAAF TH_3225|M.thermoresistible__bu REALAAARTTCEYEDLGFYS----WCLHELVEAAARVGETDTAHRALGDI Rv0890c|M.tuberculosis_H37Rv LACGAELHIY----QGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALR-Q Mb0914c|M.bovis_AF2122/97 LACGAELHIY----QGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALR-Q MLBr_01753|M.leprae_Br4923 LACGADIQAS----LGISDSMELLAELISQGDNHRQAGRLFGAASAQR-E MMAR_0123|M.marinum_M LSCSAANGTT----LGVADTLECLAELAATEGDRREAARLLASAEAIR-H Mvan_5928|M.vanbaalenii_PYR-1 LSLAAGVGAR----LEVPDTLECLARVVGDGGSHHEAARLCGAAEAIR-G MUL_2743|M.ulcerans_Agy99 IHNHHEAGNT----TLISTPLAVLAAFFDRLGRYEAAATIAGFAFHPI-T MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 AQWGDAAGAV----RARALADALSLPLADAIACHAEALRAGNGEALLT-V MSMEG_4431|M.smegmatis_MC2_155 EVLGRERPAVPLFRAVVGYSRGILEHDADALVRAAESLRAFPRPLLYAGA Mflv_1156|M.gilvum_PYR-GCK ERNGAELDRP----WQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHAR TH_3225|M.thermoresistible__bu EERAGASGTP----WGLGALAGARALLADGDEADRLFREALDHLSRSRVV Rv0890c|M.tuberculosis_H37Rv QTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQ Mb0914c|M.bovis_AF2122/97 QTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQ MLBr_01753|M.leprae_Br4923 KTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQ MMAR_0123|M.marinum_M RTGEVRLKILDAHCEVVLAELRNELGEQDFAAVWGQGAVISTDEVISYVR Mvan_5928|M.vanbaalenii_PYR-1 RTGAVRFRIYDADHETTVTTLRDALGDKAFEAAWTEGSATSITEAIAYAQ MUL_2743|M.ulcerans_Agy99 EASFP-------ELRTTISHLRDALGDHAYESFSQSGAAMTTAAMATYAY MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 AAAYRAIGDAAAAADAAAQASAAFVEGQQHQRGR---YAAALAGELAEEC MSMEG_4431|M.smegmatis_MC2_155 AADAGAELIRAQRGTEALDQLNTAFDAYSECGATADARRVGRALRRLGAE Mflv_1156|M.gilvum_PYR-GCK LPMPFERARSALTLGEVLRRLRRRDAAAAVRDALAQFEELGVPLWVARAR TH_3225|M.thermoresistible__bu VHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAERSRREL Rv0890c|M.tuberculosis_H37Rv RGRGERKRP--ARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQ Mb0914c|M.bovis_AF2122/97 RGRGERKRP--ARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQ MLBr_01753|M.leprae_Br4923 RGRGNRKRP--TTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVH MMAR_0123|M.marinum_M RGRGTRRRP--SSGWGSLTPTEHDVVRLVQEGLSNKDIAARMFISPRTVQ Mvan_5928|M.vanbaalenii_PYR-1 RGRGERKRP--SSGWASLTPTELDVVGLVSEGLSNKDIAARLFVSPRTVQ MUL_2743|M.ulcerans_Agy99 HQIDHARTE--FQAR----------------------------------- MAB_0060|M.abscessus_ATCC_1997 -------------------------------------------------- MAV_0578|M.avium_104 GGLCTPALR--TPAGLKLSGRQRDVIELAVAGLSNRQIAERLVMSVRTVE MSMEG_4431|M.smegmatis_MC2_155 RRVVATQRA--KTGWDSLTDSELTVVQLIAEGATNRAVAEHLQLSPHTVK Mflv_1156|M.gilvum_PYR-GCK IALSGLAVSG-SAVGSELTDSERRIAELAASGMSNRDVAETLFVSVKTIE TH_3225|M.thermoresistible__bu IAVGEKVRRQPLTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVE Rv0890c|M.tuberculosis_H37Rv THLTHVYAKLGLPSRVQLVDEAARRGSPS-- Mb0914c|M.bovis_AF2122/97 THLTHVYAKLGLASRVQLVDEAARRGSPS-- MLBr_01753|M.leprae_Br4923 THLTRIYSKLGLTSRVQLVQEAARHN----- MMAR_0123|M.marinum_M THLTHVYTKLGLTSRIQLVHEVARHA----- Mvan_5928|M.vanbaalenii_PYR-1 THLTHVYTKLCLASRVQLAQEAARHT----- MUL_2743|M.ulcerans_Agy99 ------------------------------- MAB_0060|M.abscessus_ATCC_1997 ------------------------------- MAV_0578|M.avium_104 GHIYRACQRVGAQSRDELATIIRSRPAGRES MSMEG_4431|M.smegmatis_MC2_155 THVRNAFAKLGVTSRAQLAQFIHRAD----- Mflv_1156|M.gilvum_PYR-GCK TNLSRVYRKLGIRSRAQLGRMLR-------- TH_3225|M.thermoresistible__bu WHLRKVFVKLGITSRRQLRAAPRVTATW---