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M. tuberculosis H37Rv Rv0890c (-)

annotation: PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR-FAMILY)
coordinates: 989948 - 992596
length: 882

RALLAQNRLVTLCGTGGVGKTRLAIQIASASELRDGLCFVDLAPITESGIVAATAARAVGLPDQPGRSTM
DSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPELTILATSREPIGMAGEITWRVPSMSITDEAV
ELFADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLEIADGLDDCFRLLAGGVRG
AVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVDKSLVV
ADDCQGRTRYRLLETVRRYALEKLGDSGEADVHARHRDYYTALAASLNTPADNDHQRLVARAETEIDNLR
AAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLST
WLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATDLARAIDDKWTL
CQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEALELSREITAE
AEASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAALE
ASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATNGWHRMVALTIRARVATARGEPE
LARDDAHAALACGAELHIYQGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIWDAGYQA
SVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDI
AKRLFVSPRTVQTHLTHVYAKLGLPSRVQLVDEAARRGSPS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0890c--100% (882)PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR-FAMILY)
M. tuberculosis H37RvRv1358-0.065.50% (884) transcriptional regulatory protein
M. tuberculosis H37RvRv0386-0.057.01% (884) LuxR/UHPA family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0914c-0.099.89% (882) LuxR family transcriptional regulator
M. gilvum PYR-GCKMflv_1156-6e-1625.25% (495) regulatory protein, LuxR
M. leprae Br4923MLBr_01753-0.059.89% (880) putative transcriptional regulator
M. abscessus ATCC 19977MAB_0060-2e-0943.48% (69) nitrate/nitrite response transcriptional regulatory protein
M. marinum MMMAR_0123-0.052.13% (890) LuxR family transcriptional regulator
M. avium 104MAV_0578-5e-1624.54% (925) transcriptional regulator, LuxR family protein
M. smegmatis MC2 155MSMEG_4431-8e-1725.64% (429) putative regulatory protein
M. thermoresistible (build 8)TH_3225-1e-1025.08% (630) PUTATIVE regulatory protein, LuxR
M. ulcerans Agy99MUL_2743-5e-7335.18% (597) LuxR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_5928-0.055.90% (882) regulatory protein, LuxR

CLUSTAL 2.0.9 multiple sequence alignment


Rv0890c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0914c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01753|M.leprae_Br4923          MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MMAR_0123|M.marinum_M               --MLASMSEIDPRAEAPLVDWSDVDMG------ELLPTGTVTLLLADVEG
Mvan_5928|M.vanbaalenii_PYR-1       -------------------------MS------ELVPTGTVTLLLADVQG
MUL_2743|M.ulcerans_Agy99           ----------------------------------------MTFLFTDVEG
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                --------------------------------------------------
MSMEG_4431|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3225|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0914c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01753|M.leprae_Br4923          LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MMAR_0123|M.marinum_M               STRLWQNQPEPMTAAVAHLDSVLATTVATHHGVRPVEQGEGDSFVVAFAS
Mvan_5928|M.vanbaalenii_PYR-1       STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR
MUL_2743|M.ulcerans_Agy99           STRLWESDPDRMRAALAAHDAVLTRTIQTHRGWLFKHTGDG--VCAAFAS
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                --------------------------------------------------
MSMEG_4431|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3225|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0914c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01753|M.leprae_Br4923          ASDATACALDLQLAPIVPVRFRIALHTGEVQISNDDV--NNVVFMMVQAA
MMAR_0123|M.marinum_M               AREAIACALDLQRSPLGPIRLRIGVHTGDIQLRDPNDPTNYIGPTINRTA
Mvan_5928|M.vanbaalenii_PYR-1       ASDAVACALALQRAPLAPIRLRIGVHTGEVRLRDEG---NYVGPTINRTA
MUL_2743|M.ulcerans_Agy99           PRSAVDAAVDAQRALELPVRMGLATG------EAEPHDADYFGAVLNRAA
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                --------------------------------------------------
MSMEG_4431|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3225|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0914c|M.bovis_AF2122/97           --------------------------------------------------
MLBr_01753|M.leprae_Br4923          GLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQ
MMAR_0123|M.marinum_M               RIRELAHGGQTVISGATQLLVVDQLPDGAWLADLGLHPLRDLPRPERVMQ
Mvan_5928|M.vanbaalenii_PYR-1       RLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQ
MUL_2743|M.ulcerans_Agy99           RVMATGHGGQILLTDSTANLIS-----GVDLLDLGSRRLRDLPAPVRVFQ
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                --------------------------------------------------
MSMEG_4431|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_1156|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3225|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        ----------------------------------------MRALLAQNR-
Mb0914c|M.bovis_AF2122/97           ----------------------------------------MRALLAQNR-
MLBr_01753|M.leprae_Br4923          LCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKR-
MMAR_0123|M.marinum_M               LCHSGLQNDFPPLRTTKSIAVHRMPARLTRFVGRIAQMADVRSLLADNR-
Mvan_5928|M.vanbaalenii_PYR-1       LCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANR-
MUL_2743|M.ulcerans_Agy99           VRAPGLRTDFPALRAPDTSPG-NLRPALTSFVARAAEIGQVQTALQVHR-
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                ---------------------MIGGELLIGRDSELAAIRRALNGADHHR-
MSMEG_4431|M.smegmatis_MC2_155      MNRRQDTPVGPSTDFFDVGGERLITPPIRGRADELKTAGALITAAARGRG
Mflv_1156|M.gilvum_PYR-GCK          -----MKAVDDFLAGLQQLQPAGLLIEGEAGIGKTTMLAGVVDAARQAG-
TH_3225|M.thermoresistible__bu      ------------------MSSRDGDVVLHGRAAEIATLRDVMSTARAGSS
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        -LVTLCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATA
Mb0914c|M.bovis_AF2122/97           -LVTLCGTGGVGKTRLAIQIAS--ASELRDGLCFVDLAPITESGIVAATA
MLBr_01753|M.leprae_Br4923          -LLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT-
MMAR_0123|M.marinum_M               -LVTLTGAGGAGKTRLAVEIAASAVDEFGDGLWYVDLAPVSHAEAVPVTV
Mvan_5928|M.vanbaalenii_PYR-1       -LVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAITV
MUL_2743|M.ulcerans_Agy99           -LVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDAV
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                -GVVIAGAAGVGKTWLARAALRR-AGASGEQIKWIVGTQSAQALPLGAFI
MSMEG_4431|M.smegmatis_MC2_155      GVLVIEGPPGIGKSRLLTEVLG---LADKCGVRTLFGEAFEYQQTVPFFS
Mflv_1156|M.gilvum_PYR-GCK          -FRVLSAHGDQSGSGLAHAAIADLFAGVQTDILDGLPELQRRAADGVLRR
TH_3225|M.thermoresistible__bu      RVLVLHGEAGVGKTALLGQLLGDAAGMRCVQVAGVESDMELAYAGLHQLC
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        ARAVGLPDQPGRSTMDSLRRFIGNRR-----MLMVLDNCEHLLDACAA--
Mb0914c|M.bovis_AF2122/97           ARAVGLPDQPGRSTMDSLRRFIGNRR-----MLMVLDNCEHLLDACAA--
MLBr_01753|M.leprae_Br4923          -------------VLDNLRRCIGDRR-----MLMVLDNCEYLLDVCAN--
MMAR_0123|M.marinum_M               ARALGLSDQPGRSTVDALARFIGEHQ-----VLVVLDNCEHLLDATAA--
Mvan_5928|M.vanbaalenii_PYR-1       ARALGLPDQPGRSTVDTIVRFIADRR-----MLVVLDNCEHLLDACAT--
MUL_2743|M.ulcerans_Agy99           AAVLGITQQAGKTVTQSVATALERRV-----RLLVFDNCEHVRDAAAD--
MAB_0060|M.abscessus_ATCC_1997      ------------------------------------------MQVSGE--
MAV_0578|M.avium_104                GLLGDAMSEPLTSVRRVIETFVARQRR---GRVVVGVDDAHLLDGLSA--
MSMEG_4431|M.smegmatis_MC2_155      LFMATLRADPPIGDVAALRELGGSADL---RYWVVHDLHNAIRAAAAQTP
Mflv_1156|M.gilvum_PYR-GCK          GDGTGGPTDERVIAAALLGAVHGSATR---TPVLVAVDDVQWLDPSSVAV
TH_3225|M.thermoresistible__bu      APLLDRLDDLPSPQRDVLNVAFGRGAGPAPGRFLVGLAVLNLLAAAGADQ
                                                                                  .   

Rv0890c|M.tuberculosis_H37Rv        --LVVELLGACPELTILA----TSREPIGMAGEITWRVPSMSITD-----
Mb0914c|M.bovis_AF2122/97           --LVVELLGACPELTILA----TSREPIGMAGEITWRVPSMSITD-----
MLBr_01753|M.leprae_Br4923          --VMTTLLGACPSLTILA----TSREPIGVAGEVIWRVSMLSPAD-----
MMAR_0123|M.marinum_M               --LLLELTGRCPAVRLLA----TSREPLGVPGEVTFLVPSLSVT------
Mvan_5928|M.vanbaalenii_PYR-1       --LIDALLGACPALAMLA----TSREPIAVAGEQTWRVPPLALDD-----
MUL_2743|M.ulcerans_Agy99           --LIEAILAGSTTVRILA----TSRERLEVPDEQLWSVPSLDVGGGV--V
MAB_0060|M.abscessus_ATCC_1997      --LVRVVVGDDHPLFREG----VVR-ALTASGQITVVAEAENGTG-----
MAV_0578|M.avium_104                --LVVHQLAQSGGVRLVV----TVRTGSHQPDAVTALWKDDLLTR-----
MSMEG_4431|M.smegmatis_MC2_155      LMIVLEDIHWADNATLLA----LRSLTTEIDVPVLWVFTARTGAGGQ--A
Mflv_1156|M.gilvum_PYR-GCK          LAFVARRVKGRVGFVVAE----RPGVGPGLPAATWLQVGTGALTR-----
TH_3225|M.thermoresistible__bu      PLLCVIDDAQWLDRVSLQTLGFVARRLMAEPVAMVFALRDDIHEALVGVP
                                      .                                               

Rv0890c|M.tuberculosis_H37Rv        -EAVELFADRASRVQPGFTIANH-NAAAVGEICRRLDGIPLAIEFAAARV
Mb0914c|M.bovis_AF2122/97           -EAVELFADRASRVQPGFTIANH-NAAAVGEICRRLDGIPLAIEFAAARV
MLBr_01753|M.leprae_Br4923          -EAVELFTERAALVQPGFSVTDG-NRQIVTEICQRLDGMPLAIELAAARI
MMAR_0123|M.marinum_M               -EATELFTDRARRVRPDFAVTDD-NTTAVTEICNRLDCMPLAIELAAARV
Mvan_5928|M.vanbaalenii_PYR-1       -DAIELFTDRARRARPDFIISAD-DAAAVSEICHRLDGMPLAIELAAARV
MUL_2743|M.ulcerans_Agy99           SAAGTLFVERAQSVAPGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRM
MAB_0060|M.abscessus_ATCC_1997      --ALELIREHRP------------DVALVDYRMPELDGTQVAAAVRRDEL
MAV_0578|M.avium_104                -LDLEPLSAAATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLSDQ
MSMEG_4431|M.smegmatis_MC2_155      VQETLSVLQRTDATFLRLAAMTPDAVADMVQDAVRARADTSLLSLAAKAH
Mflv_1156|M.gilvum_PYR-GCK          -LPVAPMSLGALHTMLSSRLGRRFSRPQIVRIAEVSGGNPLYALELARVA
TH_3225|M.thermoresistible__bu      ALAVPGLADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTY
                                          .                                           

Rv0890c|M.tuberculosis_H37Rv        RS---MSPLEIADGLDDCFRLLAGGVRGA-VQRQQTLRASIDWSHALLTE
Mb0914c|M.bovis_AF2122/97           RS---MSPLEIADGLDDCFRLLAGGVRGA-VQRQQTLRASIDWSHALLTE
MLBr_01753|M.leprae_Br4923          RT---LSLTEIADGLDDRFRLLTGGARTA-VRRQQTLRASMDWSYALLTE
MMAR_0123|M.marinum_M               RA---LSIDEIRTGLHDRFRLLTGGARTV-VRRQQTLRASVDWSHALLTE
Mvan_5928|M.vanbaalenii_PYR-1       RA---LSLTEIVDGLHDRFRLLTGGSRTA-VRRQQTLRASVDWSHGLLTD
MUL_2743|M.ulcerans_Agy99           AS---MTPIEVRDRLDHRFRLLVG-SRRG-LGRHQTLRHAVAWSYDHLSD
MAB_0060|M.abscessus_ATCC_1997      PTR--VLLLSAHDDAAIVYRALEEGAAGF-LSKE---------------S
MAV_0578|M.avium_104                MAAGRMRRVAGVWMWDGDVAVSASLSDTV-GRQLGRLTPPLALVVDTLSQ
MSMEG_4431|M.smegmatis_MC2_155      GNPFLISELVRGLGEEGRLGLSDGRAVASGFALPRRLGASMHQRLDLLSE
Mflv_1156|M.gilvum_PYR-GCK          DGAGSRPGQRLPESLSELVRLRVDGLAEDVRDVLLVAASATSPTVDLLAK
TH_3225|M.thermoresistible__bu      AVGELAGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGD
                                                                                     .

Rv0890c|M.tuberculosis_H37Rv        TEQILFRRLAPFVGGFDLAAVRAVAA--GSDLDPFSVLDQLTLLVDKSLV
Mb0914c|M.bovis_AF2122/97           TEQILFRRLAPFVGGFDLAAVRAVAA--GSDLDPFSVLDQLTLLVDKSLV
MLBr_01753|M.leprae_Br4923          SERALFRRLSAISGTFDLKVAYAVGH--DDLEEPDQVFDRLTMLIDKSLV
MMAR_0123|M.marinum_M               PERVLFRRIAVFLGGFDLDAAQAVAG--DSQVQRYQVVDELALLVDKSLV
Mvan_5928|M.vanbaalenii_PYR-1       PERVLFRRLAVFAGGFDLDGAQAITV--DGEVHRYEVVDLLTLLVDKSLL
MUL_2743|M.ulcerans_Agy99           AEKVLLERCSVFAGGFDLQSACAVAGS-ADTHDDYEVLDLLDALVGKSLL
MAB_0060|M.abscessus_ATCC_1997      TRTELVGAVLDCARGRDVVAASLTAG------------------------
MAV_0578|M.avium_104                CEPLPVDLLCDLASREDLVAAEAMGLV-TVERTPRALMARLAHP-----L
MSMEG_4431|M.smegmatis_MC2_155      GASEVVRVAAVLPDRFTAGLLAAMLE-----RSPTSLLSSLEEAVHADLF
Mflv_1156|M.gilvum_PYR-GCK          AVGVTPAAVTGLVEAAEVEGIVVIDG----NRIRFTHPVLANGIYAGADP
TH_3225|M.thermoresistible__bu      SALFLRAAALMGIAVDALAPAEAARVIQFGPRMRFFHPLMRSAAYRAADP
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        VADDCQGRTRYRLLETVRRYALEKLGDSGEAD-VHARHRDYYTALAASLN
Mb0914c|M.bovis_AF2122/97           VADDCQGRTRYRLLETVRRYALEKLGDSGEAD-VHARHRDYYTALAASLN
MLBr_01753|M.leprae_Br4923          IVEGRQGGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLD
MMAR_0123|M.marinum_M               IAESGGGPTRYRLLETVRQYAQEKLAESGEVEAVRSRHVTYYKSVAKLLD
Mvan_5928|M.vanbaalenii_PYR-1       IAENTAGRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELD
MUL_2743|M.ulcerans_Agy99           IVDRLSGRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVA
MAB_0060|M.abscessus_ATCC_1997      ------------LAGEIRKRAQP--------------------------A
MAV_0578|M.avium_104                FGELRRAGAGEMYLSTIRGRLATRLAQDQDADMQATVRRALLTLESDLDP
MSMEG_4431|M.smegmatis_MC2_155      IEDGEQLRFRHDLLREATRQSLPKSLRRAMERQSASVMLGMGAAPAEVAT
Mflv_1156|M.gilvum_PYR-GCK          QRRREVHRRLADLKTDPELRARHLALASTVADETTLTTLDAAADAARARG
TH_3225|M.thermoresistible__bu      RDRRAVHRALAEATDPGADPDRRAWHAANGVTGTDDAVAAELEKSAARAQ
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        TPADNDHQR-LVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWF
Mb0914c|M.bovis_AF2122/97           TPADNDHQR-LVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWF
MLBr_01753|M.leprae_Br4923          TPGDIDHEQ-LVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWF
MMAR_0123|M.marinum_M               APTGTDHER-RLAQAEDELDNLRSAFGWSLETRDFDSALELATSLHPVWM
Mvan_5928|M.vanbaalenii_PYR-1       APSVAGHER-RLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWR
MUL_2743|M.ulcerans_Agy99           AVWDSPRQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGF
MAB_0060|M.abscessus_ATCC_1997      GPSLSTRER--------------------EVLRMIAAGQTVPAIARALFL
MAV_0578|M.avium_104                QPELYLESA--RHAMTLLDLDLADRLANAAARAGAPGAAGVRAMNLVLLG
MSMEG_4431|M.smegmatis_MC2_155      QLARSAEPG-DREAIDALREAAQAVGRGDAGAAADLSRCALELSPADDAE
Mflv_1156|M.gilvum_PYR-GCK          APAAAAELLEWAMQLGGDSVSRRIRAAEHHVVAGDMRRAATLLEQALVDL
TH_3225|M.thermoresistible__bu      QRGGIAATATFLERAVVLTADPGLRGRRALAAAQAKRDAADSAAAHDLLA
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        GRAHLREGLSWFNSILE---------DQRFHRLAVSTAVRARALADKAML
Mb0914c|M.bovis_AF2122/97           GRAHLREGLSWFNSILE---------DQRFHRLAVSTAVRARALADKAML
MLBr_01753|M.leprae_Br4923          GRGHMYEGLAWFDSIFE---------HKNIEHLVAPKEVLARAVANKVML
MMAR_0123|M.marinum_M               TRGQGREGLAWLEAGLGNEAGLGNEAGLGNEDVQVSPSTLARALADKVTL
Mvan_5928|M.vanbaalenii_PYR-1       ARGRLQEGQAWFDAALT-----DYEARPG----EADPAVYARALADRAFM
MUL_2743|M.ulcerans_Agy99           LVNR-FEPLTWVEEAIE---------------------------------
MAB_0060|M.abscessus_ATCC_1997      APSTVKTHVQRLYEKLG---------------------------------
MAV_0578|M.avium_104                RGEQAEEALRAITDGADG----------------DASDRHYWATVRAANL
MSMEG_4431|M.smegmatis_MC2_155      HGSLIAETVGWLNRASRYG--------EAEELADMALADAASPEVEAEIR
Mflv_1156|M.gilvum_PYR-GCK          RPGVLCAIALNLLAGVR---------------------------------
TH_3225|M.thermoresistible__bu      IAERAPLSALEWARAVHLR------------------AQLEFARSRAGDA
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        STWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAE
Mb0914c|M.bovis_AF2122/97           STWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAE
MLBr_01753|M.leprae_Br4923          HAILASSPPDGSDLVTQAQQALTMAREIGDSAVLARALTACGFSSGYDTE
MMAR_0123|M.marinum_M               LAWTG-----SMAGFDDAERALTIARELADPALLIRALVARGVITAYDAD
Mvan_5928|M.vanbaalenii_PYR-1       DGHVG-----ITDRLDQAQKALAMARDIDDPALLVRALTACGGLAAYNAD
MUL_2743|M.ulcerans_Agy99           -------------------------RAVDHPKLAFLHVLASQCYTTGRVQ
MAB_0060|M.abscessus_ATCC_1997      ---------------------------VGDRAAAVAEAMRRGLLE-----
MAV_0578|M.avium_104                VWMLG-------RPADAALVLDGLAARPETPAQAAARCAVQACLDAVAAR
MSMEG_4431|M.smegmatis_MC2_155      LRLPTQTKHSSPQRVAESRRALRLRGISELTRARHLASLAYNLVLQDEDA
Mflv_1156|M.gilvum_PYR-GCK          --------MVEDDYIRAVELLERARADADNDAVLVTTLLSLGFCLGMTGS
TH_3225|M.thermoresistible__bu      GGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAALMYAGRLAPSGAL
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        AAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISG-DPNALRAAAEEC
Mb0914c|M.bovis_AF2122/97           AAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISG-DPNALRAAAEEC
MLBr_01753|M.leprae_Br4923          VARPYFAEAVELARTQGDKWTLSQIRLWGVVGFCVSG-DPVALRAAAEAA
MMAR_0123|M.marinum_M               VARPYFDEAAQLARELGDSWRLSQILSLQTRAAMAAG-DPIALEAAGEEG
Mvan_5928|M.vanbaalenii_PYR-1       VARPLLAEAVDLARSMGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEA
MUL_2743|M.ulcerans_Agy99           EAIRYADEAARLLAT--DRYEVPFGIEGWPSGACTSSGHPEQSVELCRTQ
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                CQLAAERARAALDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQAL
MSMEG_4431|M.smegmatis_MC2_155      QSRTAADEAAAAAASTGDPEAIIMAEVTHALLDSGEG-YAVRALRRLEQL
Mflv_1156|M.gilvum_PYR-GCK          FTAQLATVREAVAVAERAGVPALTSRALAMWVHVSFQAGNGLDSAALLRA
TH_3225|M.thermoresistible__bu      LEAADAVQAAFARAPEGSRAVDAFCQGMTQRIVGGISAAAAPLRVALTAM
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        RDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEA---LELSREITAEAEAS
Mb0914c|M.bovis_AF2122/97           RDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEA---LELSREITAEAEAS
MLBr_01753|M.leprae_Br4923          DDLAQEIGDRFVSLQCRLLLSIAQLWQGDMDGA---IVRSGEVVAGAEAA
MMAR_0123|M.marinum_M               LRIAEAIGDRTTSRECRGALGWVRAWRGDPIGA---LHQLGEAIAEASAA
Mvan_5928|M.vanbaalenii_PYR-1       RELADEMGDGFVSRICGWLLGIAHHFQGDLDAA---LALADGVVSESDVA
MUL_2743|M.ulcerans_Agy99           LALGHDTHTLTLG-----CLVLALTIKGQCDEA---EQLADALIESAEAT
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                RRATTSFEASHMRFWFGAVYGRACRLTGRIDEF---VSTARRLADSARDV
MSMEG_4431|M.smegmatis_MC2_155      RGIAYTNETALAHAYAGMFHANMLAVVGRLDDA---TNRAAEGIAQADRE
Mflv_1156|M.gilvum_PYR-GCK          VDLEDPEDNTPIPFRASAARGLSLALTGRLAEA---DGQLAAVAQRSAQR
TH_3225|M.thermoresistible__bu      CELARSRPAEVVHWLVPAFPVLQESAGHELWDENLVDALSEAVVRQARDA
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        NDVPTKVLGLYTQAQVLAYCG-ASAAHAIAGACI-AAATELGGVYQGIGY
Mb0914c|M.bovis_AF2122/97           NDVPTKVLGLYTQAQVLAYCG-ASAAHAIAGACI-AAATELGGVYQGIGY
MLBr_01753|M.leprae_Br4923          HDTVTRTFGLYVQTRALVHRD-VSAALVTAGLVV-EAAAELSGVYQGIGY
MMAR_0123|M.marinum_M               HDLLLLMISQVVQGFTYAYVGDADGACACADAVF-TSSAELVGANEGLGY
Mvan_5928|M.vanbaalenii_PYR-1       HDTLNGCCGELVLAHSLAQRGDTDAARAAAQVSL-NVAVEVSPVHAGLAH
MUL_2743|M.ulcerans_Agy99           RNPAALCYALLAYGFTFRDTN-----------------------------
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                PGLAYANLALLLGNAELARGAAAEAARLVQEALAGAQIHEVTSGLRPASY
MSMEG_4431|M.smegmatis_MC2_155      RSAMVLDNWAVYAGWVHLAAGRLSAARGAAESLPPPQASGAQELDVHRML
Mflv_1156|M.gilvum_PYR-GCK          GAEQDVMAVLGYRTLVAIWRGRYAEADAYAADTMERAEQLGGSMVIAFSI
TH_3225|M.thermoresistible__bu      GALAGLPQALVYRAGVHLLFGEFGLADTLLTEAESITAATDHRGPVRYHR
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        AAMTYAALAAGDVTAALEA-SDAARPILRAQPDQVTMH-QVLMAQLALAG
Mb0914c|M.bovis_AF2122/97           AAMTYAALAAGDVTAALEA-SDAARPILRAQPDQVTMH-QVLMAQLALAG
MLBr_01753|M.leprae_Br4923          AAMVFAALAMGDVAAAVEA-SEACRPHLGADHGLVAIH-LELMAAVALAR
MMAR_0123|M.marinum_M               ATAAIACQAAGDATAAWKA-YQKARELVGMDPQMAGVFPFGALAPLVS--
Mvan_5928|M.vanbaalenii_PYR-1       AALAVANLAAGDVTAAEAA-SDSATRSFGPS-EVAGIQDPNVAAQIACTR
MUL_2743|M.ulcerans_Agy99           PASALAAMRRGLRIAQDTG-NRNS--------------------------
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                FALAEAHGRLGHPAQANEA-IAGARSCVPPDFLFMHTG------------
MSMEG_4431|M.smegmatis_MC2_155      ILAEVAAHSDDRNLLLETA-NDAHDAHCTGPPGQRRACAYVLARAAWYRG
Mflv_1156|M.gilvum_PYR-GCK          CAAVAAYRGREDQARDQAAGALAQGGDYVALTVWASATLAFLEVSRGNYE
TH_3225|M.thermoresistible__bu      LIIAAWRGDAVEAARLIEAAAADGEARGEGRLMGLTGYAAALLYNGIGRY
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        GDAIAARQFANDAVDATNGW-HRMVALTIRARVATARGEPELARDDAHAA
Mb0914c|M.bovis_AF2122/97           GDAIAARQFANDAVDATNGW-HRMVALTIRARVATARGEPELARDDAHAA
MLBr_01753|M.leprae_Br4923          GDVIVARRLADNSVSATTGW-HQMAALTTRARIAMAQGEPELARADIHAA
MMAR_0123|M.marinum_M               GDLSAARRWADDVVSTSYGC-YLSVALTARARVALAQGELGQADRDSHAA
Mvan_5928|M.vanbaalenii_PYR-1       GDLDTARSLVDGAVSITRGV-HRASALTTRARIAIAQGDPEQAERNAHDA
MUL_2743|M.ulcerans_Agy99           ----------------------ETHLAAVLCRVEAKYGDPLSALDHFTLA
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                ----LALATGWALAAGGQLR-EAVATAQAAARLARDRGQPTHELACIQAA
MSMEG_4431|M.smegmatis_MC2_155      DIHEAARWLGDINLLGTPLFPHALVRLILAAQVASAAGDAGLRARVLQAA
Mflv_1156|M.gilvum_PYR-GCK          QALEAAEPLVDLYRDFPGTELMSACFMPDAIESLIAVGRLDEAEPLIAAF
TH_3225|M.thermoresistible__bu      REALAAARTTCEYEDLGFYS----WCLHELVEAAARVGETDTAHRALGDI
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        LACGAELHIY----QGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALR-Q
Mb0914c|M.bovis_AF2122/97           LACGAELHIY----QGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALR-Q
MLBr_01753|M.leprae_Br4923          LACGADIQAS----LGISDSMELLAELISQGDNHRQAGRLFGAASAQR-E
MMAR_0123|M.marinum_M               LSCSAANGTT----LGVADTLECLAELAATEGDRREAARLLASAEAIR-H
Mvan_5928|M.vanbaalenii_PYR-1       LSLAAGVGAR----LEVPDTLECLARVVGDGGSHHEAARLCGAAEAIR-G
MUL_2743|M.ulcerans_Agy99           IHNHHEAGNT----TLISTPLAVLAAFFDRLGRYEAAATIAGFAFHPI-T
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                AQWGDAAGAV----RARALADALSLPLADAIACHAEALRAGNGEALLT-V
MSMEG_4431|M.smegmatis_MC2_155      EVLGRERPAVPLFRAVVGYSRGILEHDADALVRAAESLRAFPRPLLYAGA
Mflv_1156|M.gilvum_PYR-GCK          ERNGAELDRP----WQLAIGNRCRAMLLSATGDLDGALAAAERAMAEHAR
TH_3225|M.thermoresistible__bu      EERAGASGTP----WGLGALAGARALLADGDEADRLFREALDHLSRSRVV
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        QTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQ
Mb0914c|M.bovis_AF2122/97           QTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQ
MLBr_01753|M.leprae_Br4923          KTGEVRFKVWDAGYESAVAVLRGAMGCKDFDSAWAEGAAMPIDDAITYAQ
MMAR_0123|M.marinum_M               RTGEVRLKILDAHCEVVLAELRNELGEQDFAAVWGQGAVISTDEVISYVR
Mvan_5928|M.vanbaalenii_PYR-1       RTGAVRFRIYDADHETTVTTLRDALGDKAFEAAWTEGSATSITEAIAYAQ
MUL_2743|M.ulcerans_Agy99           EASFP-------ELRTTISHLRDALGDHAYESFSQSGAAMTTAAMATYAY
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                AAAYRAIGDAAAAADAAAQASAAFVEGQQHQRGR---YAAALAGELAEEC
MSMEG_4431|M.smegmatis_MC2_155      AADAGAELIRAQRGTEALDQLNTAFDAYSECGATADARRVGRALRRLGAE
Mflv_1156|M.gilvum_PYR-GCK          LPMPFERARSALTLGEVLRRLRRRDAAAAVRDALAQFEELGVPLWVARAR
TH_3225|M.thermoresistible__bu      VHRARVHLTYGEWLRREHRRGEARRELNEAHGMFTRMGAQGFAERSRREL
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        RGRGERKRP--ARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQ
Mb0914c|M.bovis_AF2122/97           RGRGERKRP--ARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQ
MLBr_01753|M.leprae_Br4923          RGRGNRKRP--TTGWESLTPAEHNVIRLVSEGLDTKDIAARLFVSVRTVH
MMAR_0123|M.marinum_M               RGRGTRRRP--SSGWGSLTPTEHDVVRLVQEGLSNKDIAARMFISPRTVQ
Mvan_5928|M.vanbaalenii_PYR-1       RGRGERKRP--SSGWASLTPTELDVVGLVSEGLSNKDIAARLFVSPRTVQ
MUL_2743|M.ulcerans_Agy99           HQIDHARTE--FQAR-----------------------------------
MAB_0060|M.abscessus_ATCC_1997      --------------------------------------------------
MAV_0578|M.avium_104                GGLCTPALR--TPAGLKLSGRQRDVIELAVAGLSNRQIAERLVMSVRTVE
MSMEG_4431|M.smegmatis_MC2_155      RRVVATQRA--KTGWDSLTDSELTVVQLIAEGATNRAVAEHLQLSPHTVK
Mflv_1156|M.gilvum_PYR-GCK          IALSGLAVSG-SAVGSELTDSERRIAELAASGMSNRDVAETLFVSVKTIE
TH_3225|M.thermoresistible__bu      IAVGEKVRRQPLTSGDELTAQEAQIAGLAADGLTNQEIGAQLFLSVHTVE
                                                                                      

Rv0890c|M.tuberculosis_H37Rv        THLTHVYAKLGLPSRVQLVDEAARRGSPS--
Mb0914c|M.bovis_AF2122/97           THLTHVYAKLGLASRVQLVDEAARRGSPS--
MLBr_01753|M.leprae_Br4923          THLTRIYSKLGLTSRVQLVQEAARHN-----
MMAR_0123|M.marinum_M               THLTHVYTKLGLTSRIQLVHEVARHA-----
Mvan_5928|M.vanbaalenii_PYR-1       THLTHVYTKLCLASRVQLAQEAARHT-----
MUL_2743|M.ulcerans_Agy99           -------------------------------
MAB_0060|M.abscessus_ATCC_1997      -------------------------------
MAV_0578|M.avium_104                GHIYRACQRVGAQSRDELATIIRSRPAGRES
MSMEG_4431|M.smegmatis_MC2_155      THVRNAFAKLGVTSRAQLAQFIHRAD-----
Mflv_1156|M.gilvum_PYR-GCK          TNLSRVYRKLGIRSRAQLGRMLR--------
TH_3225|M.thermoresistible__bu      WHLRKVFVKLGITSRRQLRAAPRVTATW---